Toxic Or Hazardous Substance List
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Zinc Fluoride Product Stewardship Summary February 2011
Zinc Fluoride Product Stewardship Summary February 2011 ZnF2 Chemical Name: Zinc Fluoride Chemical Category (if applicable): Metal Halide Synonyms: Zinc difluoride; ZnF2 CAS Number: 7783-49-5 CAS Name: Zinc fluoride EC (EINECS) Number: 232-001-9 Document Number: GPS0041 V1.0 Zinc fluoride (ZnF2) is used in the manufacture of metals, in fluxes, chemical synthesis, and in the manufacture of special glasses.. Exposure can occur at either a ZnF2 manufacturing facility or at other manufacturing, packaging or storage facilities that handle ZnF2. Persons involved in maintenance, sampling and testing activities, or in the loading and unloading of ZnF2 packages are at risk of exposure, but worker exposure can be controlled with the use of proper general mechanical ventilation and personal protective equipment. Workplace exposure limits for fluoride ion have been established for use in worksite safety programs. When ZnF2 is a component of consumer products, users should follow manufacturer’s use and/or label instructions. ZnF2 dusts released to the atmosphere and deposited in soil or surface water in the vicinity of production sites have negligible impact on the environment. Please see the MSDS for additional information. ZnF2 s a nonflammable solid that is stable under normal conditions. Contact of ZnF2 with water or extended skin contact under moist conditions can produce hydrofluoric acid (HF), a very dangerous acid. Breathing ZnF2 dust can irritate the nose, throat, and lungs. Short-term exposure to high concentrations of ZnF2 may cause nausea, vomiting, loss of appetite and weakness. Long-term exposure to ZnF2 may cause deposits of fluorides in bones and teeth, a condition called fluorosis, which may result in pain, disability and discoloration or mottling of teeth. -
Evaluation of Antibacterial and Cytocompatible Properties Of
Dental Materials Journal 2020; : – Evaluation of antibacterial and cytocompatible properties of multiple-ion releasing zinc-fluoride glass nanoparticles Erika NISHIDA1, Hirofumi MIYAJI1, Kanako SHITOMI1, Tsutomu SUGAYA1 and Tsukasa AKASAKA2 1 Department of Periodontology and Endodontology, Faculty of Dental Medicine, Hokkaido University, N13 W 7, Kita-ku, Sapporo, Hokkaido 060- 8586, Japan 2 Department of Biomedical Materials and Engineering, Faculty of Dental Medicine, Hokkaido University, N13 W 7, Kita-ku, Sapporo, Hokkaido 060- 8586, Japan Corresponding author, Hirofumi MIYAJI; E-mail: [email protected] Zinc-fluoride glass nanoparticles (Zinc-F) release several ions, such as fluoride, zinc and calcium ions, through acid-base reactions. The aim of this study was to evaluate the antibacterial and cytotoxic properties of Zinc-F. Antibacterial tests showed that a Zinc-F eluting solution significantly reduced the turbidity and colony-forming units ofStreptococcus mutans and Actinomyces naeslundii, compared to that of calcium-fluoroaluminosilicate glass nanoparticles without zinc ions. In live/dead staining, Zinc-F eluate significantly decreased green-stained bacterial cells, indicating live cells, compared with the control (no application). Human dentin coated with Zinc-F showed suppressed S. mutans and A. naeslundii biofilm formation. Additionally, Zinc-F eluate showed low cytotoxic effects in osteoblastic and fibroblastic cells. Therefore, our findings suggested that Zinc-F exhibits antibacterial and biocompatible properties through multiple-ion release. Keywords: Actinomyces naeslundii, Biocompatibility, Dentin, Streptococcus mutans, Zinc-fluoride glass nanoparticles calcium and silicon and a phosphoric acid solution. It is INTRODUCTION assumed that Zinc-F aggregates on the dentin surface to Root caries has become a major problem in elderly close dentinal tubules and release zinc, fluoride, calcium people with exposed tooth roots caused by aging or and silicon ions through acid-base reactions, such as periodontal disease. -
Refrigerant Safety Refrigerant History
Refrigerant Safety The risks associated with the use of refrigerants in refrigeration and airconditioning equipment can include toxicity, flammability, asphyxiation, and physical hazards. Although refrigerants can pose one or more of these risks, system design, engineering controls, and other techniques mitigate this risk for the use of refrigerant in various types of equipment. Refrigerant History Nearly all of the historically used refrigerants were flammable, toxic, or both. Some were also highly reactive, resulting in accidents (e. g., leak, explosion) due to equipment failure, poor maintenance, or human error. The task of finding a nonflammable refrigerant with good stability was given to Thomas Midgley in 1926. With his associates Albert Leon Henne and Robert Reed McNary, Dr. Midgley observed that the refrigerants then in use comprised relatively few chemical elements, many of which were clustered in an intersecting row and column of the periodic table of elements. The element at the intersection was fluorine, known to be toxic by itself. Midgley and his collaborators felt, however, that compounds containing fluorine could be both nontoxic and nonflammable. The attention of Midgley and his associates was drawn to organic fluorides by an error in the literature that showed the boiling point for tetrafluoromethane (carbon tetrafluoride) to be high compared to those for other fluorinated compounds. The correct boiling temperature later was found to be much lower. Nevertheless, the incorrect value was in the range sought and led to evaluation of organic fluorides as candidates. The shorthand convention, later introduced to simplify identification of the organic fluorides for a systematic search, is used today as the numbering system for refrigerants. -
ZINC SILICOFLUORIDE CAS Number
Common Name: ZINC SILICOFLUORIDE CAS Number: 16871-71-9 RTK Substance number: 2043 DOT Number: UN 2855 Date: December 2001 ------------------------------------------------------------------------- ----------------------------------------------------------------------- HAZARD SUMMARY * Zinc Silicofluoride can affect you when breathed in and * If you think you are experiencing any work-related health by passing through your skin. problems, see a doctor trained to recognize occupational * Contact can irritate the skin and eyes. Prolonged contact diseases. Take this Fact Sheet with you. can cause skin rash and ulcers, and damage to the eyes. * Breathing Zinc Silicofluoride can irritate the nose, throat WORKPLACE EXPOSURE LIMITS and lungs causing coughing, wheezing and/or shortness of The following exposure limits are for Fluoride: (measured as breath. Fluorine): * Very high exposure can cause Fluoride poisoning with stomach pain, weakness, convulsions, collapse and death. OSHA: The legal airborne permissible exposure limit * Repeated high exposure can cause deposits of Fluorides in (PEL) is 2.5 mg/m3 averaged over an 8-hour the bones and teeth, a condition called “Fluorosis.” This workshift. may cause pain, disability and mottling of the teeth. * The above health effects do NOT occur at the level of NIOSH: The recommended airborne exposure limit is Fluoride used in water for preventing cavities in teeth. 2.5 mg/m3 averaged over a 10-hour workshift. * CONSULT THE NEW JERSEY DEPARTMENT OF HEALTH AND SENIOR SERVICES HAZARDOUS ACGIH: The recommended airborne exposure limit is SUBSTANCE FACT SHEET ON FLUORINE. 2.5 mg/m3 averaged over an 8-hour workshift. IDENTIFICATION * The above exposure limits are for air levels only. When Zinc Silicofluoride is a white, sand-like powder. -
United States Patent Office Patented June 25, 1963
3,095,356 United States Patent Office Patented June 25, 1963 1. 2 3,095,356 of fluoride uptake by the teeth. Soluble fluorides are DENTIFRICE COMPRISING INSOLUBLE SODIUM found to be taken up to a greater extent when these metal METAPHOSPHATE AND A CADMUM, TN, saits are also present with the fluoride. The proportion ZINC, MANGANESE OR IRON COMPOUND TO of the fluorides, such as aluminum, tin, or sodium fluoride INHIBIT CALCUM ON SEQUESTERNG employed in the practice of the present invention is in the Henry V. Moss, Clayton, Mo, assignor to Monsanto range of 0.05 to 1% by weight of the dentifrice composi Chemical Company, St. Louis, Mo., a corporation of tion. However, the total proportion of metal compounds Delaware w of the group of cadmium, tin, zinc, manganese, alumi No Drawing. Filed Feb. 20, 1956, Ser. No. 566,353 num and iron which are present in the dentifrice is within 11 Claims. (CI. 167-93) 10 the broader range of 0.05 to 50 weight percent. This invention relates to polishing compositions suitable According to one of the present theories as to the for use as a dentifrice base and particularly to those com molecular aggregation of phosphate salts, the insoluble positions which contain the insoluble form of sodium sodium metaphosphate containing the usual impurities, metaphosphate as an ingredient thereof. may exist as a chain-type of molecular structure, and also An object of the present invention is the provision of 5 in the form of relatively short-chain polyphosphates. Ac an improved identifice. - cording to this theory, the presently employed metal com The use of the so-called insoluble form of sodium pounds control the sequestering action of polyphosphates, metaphosphate in finely divided form has been proposed thereby controlling the type of molecular structures pre as a dentifrice. -
Material Safety Data Sheet Zinc Fluoride MSDS# 04642
Material Safety Data Sheet Zinc fluoride MSDS# 04642 Section 1 - Chemical Product and Company Identification MSDS Name: Zinc fluoride Catalog AC194920000, AC194920250, AC194922500, AC363910000, AC363910250, AC363912500 Numbers: AC363912500 Synonyms: Zinc difluoride. Acros Organics BVBA Company Identification: Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Acros Organics Company Identification: (USA) One Reagent Lane Fair Lawn, NJ 07410 For information in the US, call: 800-ACROS-01 For information in Europe, call: +32 14 57 52 11 Emergency Number, Europe: +32 14 57 52 99 Emergency Number US: 201-796-7100 CHEMTREC Phone Number, US: 800-424-9300 CHEMTREC Phone Number, Europe: 703-527-3887 Section 2 - Composition, Information on Ingredients ---------------------------------------- CAS#: 7783-49-5 Chemical Name: Zinc fluoride %: >98 EINECS#: 232-001-9 ---------------------------------------- Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - Hazards Identification EMERGENCY OVERVIEW Warning! Causes eye, skin, and respiratory tract irritation. Target Organs: Respiratory system, skeletal structures, eyes, skin. Potential Health Effects Eye: Causes eye irritation. May cause eye burns. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic inhalation and ingestion may cause chronic fluoride poisoning (fluorosis) characterized by weight loss, Chronic: weakness, anemia, brittle bones, and stiff joints. Section 4 - First Aid Measures Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get Eyes: medical aid. Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated Skin: clothing and shoes. -
123. Antimony
1998:11 The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals 123. Antimony John Erik Berg Knut Skyberg Nordic Council of Ministers arbete och hälsa vetenskaplig skriftserie ISBN 91–7045–471–x ISSN 0346–7821 http://www.niwl.se/ah/ah.htm National Institute for Working Life National Institute for Working Life The National Institute for Working Life is Sweden's center for research and development on labour market, working life and work environment. Diffusion of infor- mation, training and teaching, local development and international collaboration are other important issues for the Institute. The R&D competence will be found in the following areas: Labour market and labour legislation, work organization and production technology, psychosocial working conditions, occupational medicine, allergy, effects on the nervous system, ergonomics, work environment technology and musculoskeletal disorders, chemical hazards and toxicology. A total of about 470 people work at the Institute, around 370 with research and development. The Institute’s staff includes 32 professors and in total 122 persons with a postdoctoral degree. The National Institute for Working Life has a large international collaboration in R&D, including a number of projects within the EC Framework Programme for Research and Technology Development. ARBETE OCH HÄLSA Redaktör: Anders Kjellberg Redaktionskommitté: Anders Colmsjö och Ewa Wigaeus Hjelm © Arbetslivsinstitutet & författarna 1998 Arbetslivsinstitutet, 171 84 Solna, Sverige ISBN 91–7045–471–X ISSN 0346-7821 Tryckt hos CM Gruppen Preface The Nordic Council is an intergovernmental collaborative body for the five countries, Denmark, Finland, Iceland, Norway and Sweden. One of the committees, the Nordic Senior Executive Committee for Occupational Environmental Matters, initiated a project in order to produce criteria documents to be used by the regulatory authorities in the Nordic countries as a scientific basis for the setting of national occupational exposure limits. -
United States Patent Office Patented Sept
2,904,588 United States Patent Office Patented Sept. 15, 1959 - 2 m Three grams of the product prepared as described above was placed in a polyethylene bottle and 6 g. of water 2,904,588 was added. After the initial exothermic reaction had FLUOROPHOSPHORANES AND THEIR subsided and the solution had cooled, a white crystalline PREPARATION solid separated. This solid was recrystallized twice from water. After drying, the product melted at 159 to 161 William C. Smith, Wilmington, Del, assignor to E. I. du C. The melting point of benzenephosphonic acid is 159 Pont de Nemours and Company, Wilmington, Del., a to 161° C., and this is the product expected from the com corporation of Delaware plete hydrolysis of phenyltetrafluorophosphorane. No Drawing. Application March 26, 1956 O Nuclear magnetic resonance examination of the phenyl Serial No. 573,659 tetrafluorophosphorane showed it to have four equiv alent fluorine atoms bound to phosphorus, which indi 15 Claims. (C. 260-543) cated a square pyramidal structure. This invention relates to new compositions of matter 5 EXAMPLE II and to their preparation. Example I was repeated, using a charge consisting Organic fluorine compounds have attained considerable of 53.7 g (0.3 mole) of phenylphosphonous dichloride importance in recent years and simple and economic in the reaction flask and 65.1 g (0.3 mole) of antimony methods for their preparation are greatly desired. pentafluoride in the dropping funnel. The antimony This invention has as an object the preparation of new 20 pentafluoride was added to the phenylphosphonous di fluorophosphoranes. A further object is the provision of chloride at such a rate that the temperature of the reac a new process for their preparation. -
Itetall IC BROMIDES AS CATALYSTS in THE
QUANTITATIVE COMPARISON OF ;itETALL IC BROMIDES AS CATALYSTS IN THE FRIED.liL-CRAFTS KETONE SYNTHESIS i QUANTITATIVE COMPARISON OF MET ALLIC BROMIDES AS CATAL YSTS IN THE FRIEDEL-CRAFTS KETONE SYNTHESIS By Peter Taketoshi M,, ori Bachelor of .Arts Park College Parkville, Missouri 1945 Submitted to the Department of Chemistry Oklahoma Agricultural and Mechanical College In partial fulfillment of the r equirement for t he Degree of Master of Science 194'~ ii \ APPROVED BY: Chairman, Thesis Committee Head of the Department ~he~ ( ~uate~~ School 2174~10 iii ACKNOWLEDGEMENT The author wis hes to express his s i neere gr atitude to Dr . O. C. Dermer under whose guidance t his work has been accomplished . He also wi s hes to express hi s a ppreciation to the Chemi stry Department for t he s uppl y of chemicals used. iv TABLE OF CONTENTS "P age Introduction • • l Historical • • • • 2 Experimental • • • • 5 Procadure • • • • • • • • 9 Table of results . • • • • • • • 12 Discussion of results • .. • • • • • • 15 Summary • • • • • • • • 22 Bibliography • • • • • • • • • • 23 Biography • • • • • • • • • • • 25 1 I NTRODCCT ION T~lis is a continuation of the s t udy of catalystf for the Friedel Crafts ketone synt hesis star ted by Wilson ( .38 ), a nd continued by Suguj. tan (34), Johnson (17), and Billme ier (4). Ma ny metallic chlorides have been used in t his reacti on, but metallic bromides, as cat alyst s, have been rather neelected . It is the purpose of this work to study the ef fectiveness of some of the metallic bromides by following essentially the experimental pro cedure of Billmeier (4). 2 HISTORICAL In 1877, the French chemist Friedel and his American colleague Crafts (12) discovered the f amous Friedel-Crafts reaction, which now has s uch great industrial a pplication (7 , 13, 18, 35). -
High Refractive Index Immersion Liquid for Super-Resolution 3D Imaging Using Sapphire-Based Anail Optics
High refractive index immersion liquid for super-resolution 3D imaging using sapphire-based aNAIL optics Junaid M. Laskar1, P. Shravan Kumar2, Stephan Herminghaus1, Karen E. Daniels3, Matthias Schr¨oter1;4 1Max Planck Institute for Dynamics and Self-Organization (MPIDS), 37077 G¨ottingen,Germany 2Dept. of Physics, IIT Guwahati, Guwahati, Assam, India 3Dept. of Physics, NC State University, Raleigh, NC, USA 4Institute for Multiscale Simulation, Friedrich-Alexander-Universit¨atErlangen-N¨urnberg, Erlangen, Germany (Dated: April 21, 2016) Optically-transparent immersion liquids with refractive index (n ∼ 1:77) to match sapphire-based aplanatic numerical aperture increasing lens (aNAIL) are necessary for achieving deep 3D imaging with high spatial resolution. We report that antimony tribromide (SbBr3) salt dissolved in liquid diiodomethane (CH2I2) provides a new high refractive index immersion liquid for optics applications. The refractive index is tunable from n = 1:74 (pure) to n = 1:873 (saturated), by adjusting either salt concentration or temperature; this allows it to match (or even exceed) the refractive index of sapphire. Importantly, the solution gives excellent light transmittance in the ultraviolet to near- infrared range, an improvement over commercially-available immersion liquids. This refractive index matched immersion liquid formulation has enabled us to develop a sapphire-based aNAIL objective that has both high numerical aperture (NA = 1:17) and long working distance (WD = 12 mm). This opens up new possibilities for deep 3D imaging with high spatial resolution. Copyright 2016 Optical Society of America. One print (phenyldi-iodoarsine (C6H5AsI2) with n = 1:85 and se- or electronic copy may be made for personal use only. lenium monobromide (Se2Br2) with n = 2:1 [10]), di- Systematic reproduction and distribution, duplication iodomethane has the key advantage of being commer- of any material in this paper for a fee or for commercial cially available. -
List of Lists
United States Office of Solid Waste EPA 550-B-10-001 Environmental Protection and Emergency Response May 2010 Agency www.epa.gov/emergencies LIST OF LISTS Consolidated List of Chemicals Subject to the Emergency Planning and Community Right- To-Know Act (EPCRA), Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) and Section 112(r) of the Clean Air Act • EPCRA Section 302 Extremely Hazardous Substances • CERCLA Hazardous Substances • EPCRA Section 313 Toxic Chemicals • CAA 112(r) Regulated Chemicals For Accidental Release Prevention Office of Emergency Management This page intentionally left blank. TABLE OF CONTENTS Page Introduction................................................................................................................................................ i List of Lists – Conslidated List of Chemicals (by CAS #) Subject to the Emergency Planning and Community Right-to-Know Act (EPCRA), Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) and Section 112(r) of the Clean Air Act ................................................. 1 Appendix A: Alphabetical Listing of Consolidated List ..................................................................... A-1 Appendix B: Radionuclides Listed Under CERCLA .......................................................................... B-1 Appendix C: RCRA Waste Streams and Unlisted Hazardous Wastes................................................ C-1 This page intentionally left blank. LIST OF LISTS Consolidated List of Chemicals -
Chemical Names and CAS Numbers Final
Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number C3H8O 1‐propanol C4H7BrO2 2‐bromobutyric acid 80‐58‐0 GeH3COOH 2‐germaacetic acid C4H10 2‐methylpropane 75‐28‐5 C3H8O 2‐propanol 67‐63‐0 C6H10O3 4‐acetylbutyric acid 448671 C4H7BrO2 4‐bromobutyric acid 2623‐87‐2 CH3CHO acetaldehyde CH3CONH2 acetamide C8H9NO2 acetaminophen 103‐90‐2 − C2H3O2 acetate ion − CH3COO acetate ion C2H4O2 acetic acid 64‐19‐7 CH3COOH acetic acid (CH3)2CO acetone CH3COCl acetyl chloride C2H2 acetylene 74‐86‐2 HCCH acetylene C9H8O4 acetylsalicylic acid 50‐78‐2 H2C(CH)CN acrylonitrile C3H7NO2 Ala C3H7NO2 alanine 56‐41‐7 NaAlSi3O3 albite AlSb aluminium antimonide 25152‐52‐7 AlAs aluminium arsenide 22831‐42‐1 AlBO2 aluminium borate 61279‐70‐7 AlBO aluminium boron oxide 12041‐48‐4 AlBr3 aluminium bromide 7727‐15‐3 AlBr3•6H2O aluminium bromide hexahydrate 2149397 AlCl4Cs aluminium caesium tetrachloride 17992‐03‐9 AlCl3 aluminium chloride (anhydrous) 7446‐70‐0 AlCl3•6H2O aluminium chloride hexahydrate 7784‐13‐6 AlClO aluminium chloride oxide 13596‐11‐7 AlB2 aluminium diboride 12041‐50‐8 AlF2 aluminium difluoride 13569‐23‐8 AlF2O aluminium difluoride oxide 38344‐66‐0 AlB12 aluminium dodecaboride 12041‐54‐2 Al2F6 aluminium fluoride 17949‐86‐9 AlF3 aluminium fluoride 7784‐18‐1 Al(CHO2)3 aluminium formate 7360‐53‐4 1 of 75 Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number Al(OH)3 aluminium hydroxide 21645‐51‐2 Al2I6 aluminium iodide 18898‐35‐6 AlI3 aluminium iodide 7784‐23‐8 AlBr aluminium monobromide 22359‐97‐3 AlCl aluminium monochloride