FILE copy ecor U . 5. D EPA RTM EN T OF Augus t 23, 1966 N ATIONAL INSTITUTES OF HEALTH H EALTH. E DUCATION. ANO W ELF ARE Vol. XVIII, No. 17 PUBLIC HEAL TH SERVIC E Suggestion System NIDR Reorganized Change Seeks to To Spur Attack Speed New Ideas On Dental Ills A more effective attack on the The DREW Suggestion System Nation's dental ills, which each is now being administered inde­ year cost Americans $2.5 billion, pendently of the I ncentive Awards was announced recently by Dr. System under new procedures out­ William H. Stewart, Surgeon Gen­ lined in the HEW General Admin­ eral of the Public Health Service. istration Manual (Chapter 8-90; This is the aim, he said, of the PHS Supplement Chapter 8-00). recent reorganization of the grant­ According to W. K. Holl, Chief supported research and educationi,I of the Management Policy Branch, programs of the National Institute OA:\l, who was recently named of Dental Research. Suggestion Coordinator for NIH, Dr. Stewart fur ther noted thnt the reason for the DHE\V change­ the reorganization will help to b,>t­ over is to stimulate employe inter­ ter define ar·cas of needed resear~h est and participation in the Sug­ and spur studies on these problems. gestion System, especially among A patient unde rgoes hea rt cathete rization in the Surgical Wing of the CC . It will also help identify those re­ members of the professional staff, Guided by fluoroscopy on TV screen, the doctor threods o cothe ter into heart search contributions which have and to eliminate delays between chambers ta diag nose de fects. The new automatic heort-trocking system helps the receipt of suggestions and ac­ cardiologists study heart problems.- Photo by Sam Silverman. tion upon them. Dy Tony Anastasi COs Eligible An automatic "heart-tracking" system that may prove to be a useful It is pointed out that for the tool for analysis of the motions of t:he heart and other internal organs first time PHS commissioned of­ has been developed by biomedical engineers in the Division of Research ficers are eligible to participate in Services. the Suggestion System along with The system, which uses a tele­ all other full-time and part-time vision video signal from the X-ray Mr. Barrett, who will be a soph­ employes of NIH. The only excep­ fluoroscope to track and record omore next fall at the Massachu­ setts Institute of Technology, is tions are persons serving in a con­ heart motion, was developed by Dr. Krcshove r Dr. Driscoll sultant capacity. William Schuette, Bob Gibbons, studying elect rical engineering and working at NIH during the sum­ To implement the speed-up in Homer Chalifoux and Mike Bar­ promise for application in the com­ mer months. processing suggestions, it is being rett, all of the DRS Biomedical munity and hasten the availability proposed that authority to approve Engineering and Instrumentation Used in Heart Study of their benefits. (Sec SUGGESTION, Pouo 7) Branch. The instrument is used to sup­ The development of scientific port 1,esearch being performed by manpower resources and the con­ Dr. Allen Simon of the Clinical duct and application of resea1ch Study Underway on Gout-Like Syndrome Center Diagnostic Radiology De- arc combined in four major pro­ 'lopartmcnt. gram areas covering: 1) denLal That Causes Retardation in Male Infants "With this new system, cardi­ caries and bard tissue studies , ologists arc able to study t he mo­ 2) periodontal disease and soft t1s- A field study team of medical investigators from the general clinical tions of the beating heart and ana­ research center at the University of Miami recently began tracing vic­ lyze the measurements by playing tims of a strange, gout-like syndrome that causes seve1,e mental retarda­ back the TV tape," said Mr. tion and cerebral palsy in male in­ in the blood. Schuette. fants, the Public Health Service Prior to development of this new announced recently. H igh ulic acid levels in adults produce a different disease called system, radiologists had no con- Team Visits 2 States gout, a painful arth1·itic condition (See BIOMEDICAL, Paue $ ) The team, composed of pedjatri­ caused by the accumulation of cians, social workers and nurses, urate crystals around the joints. traveled for a week through Ala­ Abnorma lities Caused BULLETIN bama and Florida to examine mem­ Dr. Likins Dr. Malone bers of several families in whom In infants, elevated uric acisearch ·Information, for the information of employee~ of the and over the past four years have taken their toll not only in the short­ National Institutes of Henlth, principal research center of the Public ening of human tempers but in the weakening of trees and other plants Health Service, U.S. Department of Health, Education, and Welfare, and on the NIH reservation. circulated by request to all news media and interested members of the Sueh a lengthy period of heat and drought has seldom been experienced medical- nnd science-related fields. The NIH Remrd content is reprinl­ in Washington, What the final ef­ able without permission and its pictures are available on request. fects rm the tn!ls will he cannot the immediate effects of lack of be predicted with any degree of NIB Record Office...... Bldg. 31, Rm. 4813. Phone: 49-62125 moisture but also the resultant certainty. weakening of the trees, he said, Editor ...... E. Kenneth Stabler The large trees are being hard­ making them easy prey to insects Staff Correspondents est hit because their roots al'e deep and disease. r.P.orgia11a Brimijoin, NCI; Tony Anastasi, DRS; Bowen Hosford, CC; and much moisture is necessary to Nor is the damage entirely due Mary Anne Gates, NIAMD; Marie Norris, NTDR; Ed Long, NIMH; penetrate the soil deeply enough t.o t-0 the lack of rain. Man has com­ Robert SchreihHr, NINDB: :Martha Mader, NIAID; Faye Peterson, DDS; reach them, according- to Milford pounded the problem by excavating Wanda Warddell, NIGMS; Beverly Warran, DRFR; Dick Turlington, D. Myers, Chief of tlie Grounds the land for construction of uew D~q.; Gary Goldsmith, NHI; Francel! Mills, OAM; Dan Rogers, NICHD; Maintenance and Landscaping Sec­ buildings, thus damaging many of tion of the Division of Research T~NIH Record rt>scnes the right to rnal,e corrections, changes or the feeder roots closer to the sur­ Se-i-vices. f ace and lowering local water d.,Jrtiun• in suhmitted copy in conformity with the policy of the paper The damage is due not only to and the Department of Health, Education. and Welfare. tables. Dr. Cosmldes Speaks at Leaves A~e S.:orched Dr. Delashmutt Is Reassigned The loss of these roots has lim­ NEWS/rom Toxicology Conference ited the ability of plants to main­ Snrg. Gen. Willi>im H. Stewart fa.in the water supply that keeps hus nnnounccd the appointment of Dr. George J. Cosmides, coor­ the leaf temperature down, there­ Dr. Robert E. DeLashmutt to the dinator of Pharmacology-Toxicol­ hy ie>.1.11sing the le.aves to sco1·ch. PERSONNEL Office of the Surgeon General. In ogy programs for the National In­ What little rain we have had Pr.rt f! of i! parts -a continua­ his new pc,sL, Dr. DHLaKhmutt will ~titul-e of General l\Iedical Sciences, has saturafod the sudac1c> b11t has tion of reminder~ crmcerniug po­ bo Spcciul Assistant to Deputy emphasized the need for compre­ not been sufficient to roach the litical activity that appeared in Surg-. Gen. Leo J. Gehrig. hensive training and increased deep root system. the Aug·. 9 issue of the NJ/I With the PHS since HJ49, Dr, manpower in toxicology in an ad­ DHL,rnhmutt ~erved most rHcently d rn~s "t the 1D66 Gordon Research The steps that have been taken Record: to alleviate this situation bv the in the Service's Division of Hos­ Conference on Toxicology and 11, The Civil Service Commissicm Grounds Maintenance and Land­ p;tals w herH hE wa~ A ssi~tant Safety Evalu atitms in Meriden, has cun$istently expre5sed the view scaping Section are many and Chief for the past ~·ear. N.H., Aug. 8-1~. · that it believes all citizens should varied, Mr. Myers explained. Tn disc11ssing "Training in Toxi­ be encouraged to register and to Weather-proofing sprays have vote, and that no impediment cology," Dr. Cosmides stre~sed that List of Latest Arrivals future training should devebp be-en applied to, slow the water loss shouhl be permitted which would through the leaves. In AUgust of hamper an individual from partici­ Of Visiting Scientists toxicologists who would provide a rational basis for the. safe. and 19()/i, new •S)lrinkler lines were com­ pating in registration activities pleted to accommodate some areas and voting, 8/1,-Dr. lwao Hirono, Japan, effective use of drugs and other Laboratory of Experimental Path­ ehemical~ while minimizing their that were othei-wise hard to, reach. 12. A Federal employe may be ology, Sponsor: Dr. G. Laqucur, risks. Soil Revitalized excu~ed for a reasonable time to NIAMD, Bldg. 4, Rm. 326. Pointing to the present crucial ,,ote or to register to vote. If in The soil has been seeded, fort-i­ 8/1-Dr. Fuminori Sakai, Japan, manpower shortages in toxicohJ2.'Y, doubt nl,out what is considered lized, partially limed, and aerified Laboratory of Kirlney and Electro­ Dr. Cosmides said that, at current "reasonable," check with your I/D to loosen it and form a reservoir lyte Metabolism. Sponsor: Dr. R. rates, during the next live yearn Personnel Office. to lmld what water there is and to Berliner, NHI, Bldg. 10, Rm. institutions will produce only 13 provide a mulch that will slow · 13. A Ff'dHral employe may ac­ 7N214. toxicologists a year with doctoral down Hvaporation. · cept an appointment as a registrar 8/8-Dr. Ro~ita Tan Li, Taiwan, degrees. HH a,lM.A. pastoral training course offered at degree from Brown University. the Clinical Center. Participants In 1951 Dr. Cassedy accepted an in the 11-week course were Palmer appointment with the U.S. Infor­ Hartl, of St. Louis, Mo.; Norman mation Agency, and served as Ex­ Griffith, Victoria, Tex.; Elijah ecutive Director of Binational Cul­ White, Leesburg, Va., and Buddy tural Centers in Haiti and Burma Dugan, Shreveport, La. until 1955. At that time he re­ The four are second-year stu­ turned to Brown University, re­ dents at Virginia Theological Sem­ ceiving his Ph.D. degree in 1960. inary, Alexandria. Mr. Hartl com­ After a year of teaching history mented that the course had im­ at Williams College, he rejoined pressed on them the need for pa­ the USIA, and until 1962 served tients to be restored spiritually as as Executive Director of the Pak­ well as physically. istan-American Cultural Center in The Clinical Center is accredited In o postorol training session ot the Clinical Center ore (I to r) Palmer Hortl, Karachi. by the Council for Clinical Train­ Norman Griffith, Elijah White, Buddy Dugon ond CC Choploin Robe rt Bruce ing, Inc., as a pastoral training Robey. Standing is Choploin LeRoy G. Kerney, Chief of the CC's Deportment NIH Positions Listed center. of Spiritual Ministry. Dr. Cassedy came to NIH in 1960 as a Science Administrator, Vidifilm Process Yields Three Different Kinds of Recordings Simultaneously and in 1963 was promoted to the position of Executive Secretary of In a joint effort with the Na­ era! types of visual records at once. techniques is made possible by the History of the Life Sciences tional Naval Medical Center, the According to Dr. Malcolm S. mounting a television camera and Study Section. Since 1965 he has Ferguson, Chief of MAPB, a video­ a motion picture camera side-by­ also served as Executive Secretary Medical Arts and Photography tape is made that can be played side on the same tripod, Dr. Fergu­ of the DRG Advisory Committee Branch of the Division of Research back immediately. Concurrently, a son explained. on Scientific Publications. Services recently made use of a regular motion picture film is pro­ The result of both cameras using Dr. Cassedy has published sev­ system of motion picture produc­ duced, as well as a kinescope which the same optics and working to­ eral articles dealing with his field tion known as Vidifilm. may be used as a rough-cut, work­ gether is the simultaneous produc­ of study and is author of the book, This system, used to cover two print for a motion picture. tion of a videotape, a motion pic­ Charles V. Chapin and the Public N IH film projects, produces sev- This combination of recording ture and a kinescope. Health Movement. Page 4 August 23, 1966 THE NIH RECORD Dr. Murray A. Diamond, Dr. Mary Reid, a Leading Authority on New Blood Platelet Study Asst. Surgeon General, Guinea Pigs, Pursues Research at 81 Yields Coagulation Data Will Retire on Sept. 1 By Mary Anne Gates Science may be a step closer to Dr. Mary E. Reid looks too sweet and grandmother ly to be perhaps the understanding the coagulation Asst. Surg. Gen. Murray A. Dia­ world's leading authority on guinea pig nutrition, but she is._ And, at 81, process thanks to a recent study mond will retire Sept. 1 from the she's still productive in the field of research she chose back m 1920. of blood platelets. U.S. Public Health Service. Dr. Reid retired officially from the Laboratory of Nutrition and En­ Following release from active docrinology, National I nstitute of While it is well known t hat hu­ duty, he will become Executive Di­ Arthritis and Metabolic Diseases, man blood platelets contain rich rector of Touro In­ eleven years ago. But she stayed as firmary in New Or­ stores of a lipid substance which a "guest worker,'' continuing her can markedly accel01·ate blood clot­ leans, La. laboratory research with guinea As A s s i s t a n t pigs until just a year ago. ting, this substance has neve1· been Surgeon General in Now she spends two six-hour localized within the platelet and the Commissioned days a week at NIH, compiling the the mechanism by which it is made Corps, Dr. Diamond data she obtained in earlier studies. available to coagulation has not served in a var iety The latest of her more than 50 been known. of assignments in publications, an article on "Methi­ The present study shows that h i s distinguished onine and Cystine Requirements of during an early stage of clot de­ 30-year career. Young Guinea Pigs," appears in a During the 1962- Dr. Diamond velopment in human platelet-rich recent issue of the J ournal of Nu­ plasma, platelet granules give rise 66 period, he was top health man­ trition. power officer of the PHS-the ma­ to pa1ticles resembling lipid mi­ jor health agency of the U.S. Gov­ Pioneered ot NIH celles. These are ejected through ernment. Dr. Reid joined the staff of the the pl,atelet membrane into the Dr. Mory E. Reid, authority on guinea surrounding plasma pr ior to plate­ For his outstanding work, Dr. old National Instit ute of Health pig nutrition, holds one of the oni­ Diamond was the first Commis­ 30 years ago when it was located let aggregation. These findings ma ls being used in NIAMD nutrition strongly suggest that such par­ sioned Officer to receive two of the in Washington on a five-acre tract studies. Dr. Reid retired 11 years ogo Service's honor awards, the Com­ at 25th and E Sts., N.W. ticles are the active lipid s ubstance ot the oge of 70, but still continues cont1·ibuted by platelets to coagu­ mendation Medal and the Meritor­ She had previously conducted re­ her work ot NIH.-Photo by Tom Joy. ious Service Medal. search on plant nutrition with the lation. U.S. Depa1tment of Agriculture of plant nutrition, Dr. Reid was Background Given Investigation Described and, prior to that, had taught high perhaps the first to show the im­ Multiple samples of human A psychiatrist as well as ad­ school biology and college botany. portance of light in the synthesis platelet-rich plasma were fixed in ministrator, Dr. Diamond's other Aftel' earning a Ph.D. in plant of ascorbic acid in the plant. osmic acid or gluteraldehyde-osmic activities included academic and nutrition from the University of She found that the vitamin C clinical teaching of medical stu­ Wisconsin in 1923, Dr. Reid re­ acid, and platelet ultrastructure content o.f green leafy vegetables was studied by electron microseopic dents in psychiatry. He was also ceived a postdoctoral fellowship to growing in the field is highest Assoc. Prof. of Clinical Psy­ work ,vith Dr. L. B. Mendel at techniques. Anticoagulant was after several hours exposure to the added to similarly prepared con­ chiatry at the University of Yale Universit y. There she obtain­ sun, suggesting that afternoon or Kentucky, lectured on public serv­ ed experience with problems in ani­ trol platelet samples. The investi­ evening is the optimal time for gators also examined lipids ex­ ice broadcasts on Narcotic Addic­ mal nutrition that was to be of harvesting. tion, and led seminars at Indiana U. great value when she began her tracted from platelets and human Dr. Reid's cunent un dertaking work with guinea pigs at N IH . brain and processed in a manner A highly respected professional, is a book on ascorbic acid and min­ known to supply lipid acceleratory his organization memberships in­ Develops Diet eral nutrition which will represent activity to in vit-ro coagulation. clude American Medical Associa­ the culmination of her studies over One of Dr. Reid's main accom­ Only platelets fixed in gluteral­ tion, American Psychiatry Associa­ the last 35 years. plishments has been the develop­ dehyde-osmic acid solution under­ tion, American College of Physi­ ment of a purified diet for guinea cians, American Association for went transformation into lamellar pigs. Since their natural diet con­ particles with the configuration of the Advancement of Science, sists of alfalfa and whole grains, Dr. Hemphill Transfers American Public Health Associa­ lipid micelles. These were released the purified diet is made up of corn To BSS in Los Angeles through the platelet cell membrane tion, American Hospital Associa­ starch, cane sugar, purified soy tion, Alpha Omega Alpha, and the prior to platelet aggregation; sub­ bean protein or casein, corn oil, Dr. Fay M. Hemphill, Scientific sequently the platelet membrane Board of Directors of the National salts and vitamins. The elimination and Technical Information Officer Health Council. re-formed rapidly. Such particles of appropriate items from this diet of the National Cancer Institute Dr. Diamond and his wife, the produces clear-cut deficiencies. were essentially identical in size since 1963, recently transferred to and configuration to the micelles former Irene Roth of Flushing, Using the plll'ified diet, Dr. Reid the Bureau of State Services, Office N.Y., have two sons. Stephen, 23, formed by extracted platelet and elucidated the vitamin requirements of Pesticides, where he will serve brain lipids in vitro. is presently interning at the of the guinea pig and determined as Senior Coordinating Epidemiol­ USPHS Hospital in San Francisco; the animal's requirements for a ogist , stationed in Los Angeles. Study Not Conc lusive and Richard, 20, is a junior at number of essential •amino acids. Dr. Hemphill's new assignment The investigators were unable to Loyola School of Dentistry, New Success Explained will be to help evaluate long-term prove conclusively that platelet Orleans, La. effects on the human popula tion of One of Dr. Reid's associates at­ micelles are active in coagu1ation. tributes her unparalleled success in chemical contaminants in the en­ Nevertheless, the origin of lipid Dr. Robert Stubblefie ld Named developing information about gui­ vironment. micelles from platelet granules, To Natl. Mental Health Council nea pig nutrition to her ability to A native of Texas, Dr. Hemphill their release from platelets early "understand the psyche" of this received the B.S. and M.Ed. degrees in clot development, and t heir Appointment of Dr. Robert L. animal. "She gave personal, con­ from the University of Texas, and s~uctural similarity to micelles of Stubblefield to the National Ad­ stant attention to their habits,'' he the M.S. and Ph.D. degrees in epi­ other lipids active in accelerating visory Mental Health Council was said, "and devised special feeding demiology from the University of coagulation suggest that platelet announced recently by Dr. W illiam and caging techniques." Michigan. micelles are the active platelet lipid H. Stewart, Surgeon General of the As a result, she was the first to After serving in a number of substances made available in Public Health Service. succeed in taking animals at three public health positions he joined coagulation. Dr. Stubblefield is Professor and days of age from their mothers to the faculty of the University of Results of t his study by NIAMD Chairman of the Department of put them on the purified diet, thus Michigan where he a ttained the grantee Dr. W. Krivit and a ssoci­ P sychiatry, Southwestern Medical permitting a greater opportunity rank of professor. ate Dr. J. G. Whjte of the Univer­ School of the University of Texas. to produce marked deficiency ef. In 1959 he came to NIH as As­ sity of Minnesota, supported in His term begins Oct. 1, 1966, and ects. sistant Chief of the Division of part by a NIAID grant, appeared runs t hrough Sept. 30, 1970. Also quite successful in the area Research Grants. in t he publication, Blood. THE NIH RECORD August 23, 1966 Page 5 REORGANIZATION Graduate Program Holds New Clinical Nursing Experts at the CC (Conti·1tued from Page 1) Registration Sept. 9-16 1 It, Too' ical, applied and epidemiologic re­ Sixty-seven courses are being of­ Can Have Their Cake and Eat search directly concerned with the fered by the Graduate Program at By Bowen Hosford major oral diseases, according to NIH in the Fall 1966 semester in Dr. Seymour J. Kreshover, Director "Chief" or "Indian"- which is it more satisfying to be? Does one con­ the following departments: tribute more to NIH by doing work or by planning it and sup-ervising of the Dental Institute. Similarly, Behavioral and Social Sciences, each area will encompass training others who do it? Biochemistry, Chemistry, Genetics, These questions are lively ones among medical professionals, includ­ grants, fellowships and career de­ Mathematics, Statistics, Physics, velopment awards. ing, of course, nurses. More than Medicine and Physiology, Micro­ a year ago, the Nursing Depa-1t­ a different nursing service. She A small expert committee of biology and Immunology, Lan­ ment staff of the Clinical Center may be requested by any head advisers will be appointed for each guages and General Studies. Reg­ considered the problem in a series nurse or staff nurse to work out a area, and special ad hoc consultant istration will be held Sept. 9 of evaluation meetings. problem. groups will be called on as neces­ through 16, except Sunday, from According to Louise C. Ander­ Most of her time is spent in di­ sary. 10 a.m. to 4 p.m. Classes begin the son, Nursing De­ week of Sept. 19. rect care of patients, particularly Dr. Driscoll to Direct partment Chief, in difficult situations. She plans The programs will function un­ Catalogs a1·e available in offices t:iey recognized her own routine and sets her own der the broad direction of Dr. Ed­ of the Graduate Program in Bldg. this paradox: a schedule. ward J . Driscoll, Associate Director 31, Rm. 3B06, Ext. 66371. Admis­ nurse who is pro­ moted to super­ If patient-care needs permit, she for Extramural Programs of NIDR. sion to the courses is open to the can spend the day in the library, public, provided the students meet visor usually re­ learning more about a disease and Robert C. Likins, D.D.S., will the prerequisites stated in the cat­ ceives more pay, serve as Chief of the area of Dental but she gives up the nul'Sing requirements it poses. alog. She has access to any CC depart­ Caries and Hard Tissues. This pro­ Textbooks for the courses are the satisfaction of gram will encampass st udies of d i r e c t nursing ment if she needs assistance. available in the Foundation Book­ An important proviso is this: the formation, calcification, com­ store Bldg. 31, Rm. 3B05, and may Mrs. Anderson care--which is her position and fine structure of dental basic reason for being in nul'Sing. she must communicate with all be p~rchased at the time of regis­ other nurses. She not only com­ tration. Another consideration was the shoitage of nurses that troubles municates what she learns about Additional books in the sciences hospitals t hroughout the country. new situations; she passes on to are also stocked and may be pur­ The CC administration had al­ others her basic skiJls. chased 9 to 4 daily. The bookstore ready taken many steps.. And here another paradox has will order any book upon request, For example, some duties have become evident: when the Nursing if the purchaser will call Ext. been delegated ·to nursing assist­ Department leaders lost these su­ 66371. ants and to Red Cross hospital pervisors, they did not lose the volunteers. supet-v:isory contribution that the Still, it was bothersome to see nurses had made. Manual Standardizes The difference is that commupi­ Dr. Nelson Dr. Hisooko some of the CC's specially skilled Cleaning Procedures nurses diverted to administrative cation is now lateral rather than vertical. hard tissues as well as work di­ duties. The Clinical Center's Department Chief or Indian? By some al­ rected at the causes, treatment and Could nursing leaders afford to of Environmental Sanitation re­ chemy, the Clinical Nursing Ex­ prevention of tooth decay. lose some of their supervisors by cently published a revised and ex­ 1·eturning them to direct patient perts, at one and the same time, Dental caries was found to be are both. panded Cleaning P rocedure Man­ care? Could t;hey afford to pay the number one health problem ual. among children in Operation Head practitioners as much as super­ The manual, first published in visors? Would supervisors be hap­ Start, and it affects more than 95 1965, is a feature in the depart­ Dr. Neurath Named to Council percent of the total population. py if they lost their titles? ment's training program. It stand­ Those are the "Indian-Chief" Dr. Hans Neurath, Professor and Assignments Listed ardizes cleaning procedures that questions, in different language. Chairman of t he Depar tment of Thomas E. Malone, Ph.D., will have been demonstrated to be effi­ Today, as a result of the discus­ Biochemistry at the University of administer the Periodontal Disease cient. A separate section gives sions, seven CC nurses, formerly Washington, has been appointed to and Soft Tissue Study area. Perio­ equipment specifications and main­ "supervisors," are completing their the National Advisory General dontal disease, the chief cause of tenance instructions. first year as "Clinical Nursing Ex­ Medical Sciences Council, the Pub­ tooth loss after 35, affects an esti­ Complimentary copies are being perts." This is a new, unique title. lic Health Service announced re­ mated 67 million American adults. distributed to Federal health offices. Each expert nurse is assigned to cently. In addition to studies of normal and diseased periodontal tissues, methods and materials for pros­ this program will include investiga­ thetic, implant, restorative and pre­ tions of oral cancer, saliva and the ventive dentistry will be concen­ salivar y glands, oral microorgan­ trated in this program area. In­ isms and oral ulcerations such as cluded in this category will be ap­ canker sores. propriate field trials to assess the benefits to population groups of K. Kenneth Hisaoka, Ph.D., will promising laboratory leads. direct the Oro-Facial Growth and Development Program, which will "While these four categories will serve to sharpen the focus of our be concerned primarily with stud­ ies in clf'J't lip and palate and support , as well as emphasize the orthodontics. breadth of responsibility in the dental and relevant sciences," Dr. One out of every 750 children Kreshover said, "they are by no is born with a cleft lip or palate. means all inclusive. Meritorious Disciplines such as surgery, psy­ grant applications that do not chology, sociology and speech ther­ clearly fall within these areas will apy will be included as well as the continue to be encouraged and sup­ basic sciences related to etiology ported. and treatment. "An essential additional consid­ Robert J. Nelson, D.D.S., is in eration is that this new structure charge of Biomaterials and Special will have a built-in flexibility that From le ft: Evelyn Bridges of the Clinical Cente r's Neurology Nursing Se rvice, Projects. Investigations in the de­ will permit the development of new Deportment of Nursing, helps Mory Ann Kavanagh, o ne w employe, apply velopment and use of improved program areas as needs arise." o head dressing.-Ph oto by Je rry Hecht. P age 6 August 23, 1966 THE NIH RECORD RETARDATION DRG Has Documents of 'Everybody Gets Into the Act' at CC's (Continmd from Pa.oe 1) Research Grants Index tionalized by the age of puberty. For Administrative Use Festive 4th Annual Patients' Carnival A mysterious urge toward self­ Everybody got into the act at the Clinical Center's Fomth Annual destruction drives the affected chil­ Companion documents to the Patients' Carnival here Aug. 10 and made it the biggest and best ever. dren to intense self-biting of their fifth edition of Research Grants The carnival was held in the wooded area adjoining the Apartment mouth area and fingers. Unless Index, FY 1965, published recently Building. they are restrained, the children by the Public Health Service, are Surrounded by all the trappings available for administrative use A real sideshow featured K. M. continue to bite any part of their of the midway, Dr. Robert M. Far­ and !!he Barnns, a rock and roll body within reach. only from the Research Documen­ rier, CC Associate Director, cut a combo; Peggy Holt's Hawaiian By contacting families that are tation Section, Statistics & Analy­ red, white and blue ribbon at 7 p.m. Dance Group, and an impromptu known to have an afflicted relative, sis Branch of the Division of Re­ to begin the festivities. performance a la Jimmy Durante t;he field study team hopes to learn search Grants. These documents For several hours hoSJ)ital rou­ by one of the clowns. are: more about the causes and symp­ tine for about 230 patients and The game booths offered turtle toms of the unusual disease. The Statistical Summary of the races featuring four hard-back con­ Research Grants Index, a 365-page Headed by Dr. William L . Ny­ testants named Ringo, P aul, John booklet that provides a concise re­ and George. There were bean-bag han, one of two men who discov­ capitulation of the contents of the ered the syndrome in 1963, the throws, ring tosses, a pop-gun Index's Vol. I. Subject headings shooting gallery and a wheel of team is taking blood and urine are arranged as they are in the samples to determine the levels of fortru1e. Index in alphabetical sequence. The Gypsies were available to ana­ uric acid present in suspect family frequency with which each term is members. lyze handwriting, and helium-filled used in indexing PHS projects is balloons carried patients' postcard Transmitted by Females tabulated according to the Inst i­ messages into outer space. Genetic data that the team dis­ tute or Division which supported covers will help show how the dis­ the project. Prizes to Be Given ease is transmitted through the Vol. II Summarizes Sender of the card that is mailed female line to the male children. back from the most distant "plan­ The Statistical Data on Sources et" ,vill receive a prize, and the After the team finis'hed its field of Publications Cited in the Re­ study Aug. 15, Dr. Nyhan had person who returns the w inning search Grants Index, a 140-page card will also receive a prize. hoped to make arrangements for booklet that summarizes grantee the children and relatives to enter Taking a im from his mother's arms, Arnold Sperling, Chief of the bibliographic data contained in the Clinical Center's Patient-Activities the general clinical research center Index's Vol. II. Sources of articles Mark Sinner, 3 , whose brothe r is a at Miami for further study and CC patient, tries to douse a candle Section, said the show couldn't have published as a result of PHS re­ gone on without the assistance he treatment. search grant support, and a fre­ from 5 paces. In background Hanne ke Mays, a United Presbyte rian volunteer had from generous NIH staff mem­ General clinical research centers quency list of journals in which bers and community groups. PHS grantees are published ap­ from Bethesda, chec ks results of the are particularly well adapted for watery barrage. Mark and his ,mothe r, The Plant Engineering Branch, the clinical study of various dis­ pear in this document. DRS, supplied the men who built eases. Each ce.nter has its own re­ In addition, the booklet lists sep­ Mrs. William Sinner, are from the Bronx, H.Y. and painted the booths, made the search· bed.s, staff, laboratory and arate journal-frequency tabulations signs and installed the lighting. supporting facilities to provide the for each PHS/NIH Institute or their guests was replaced by NIH transportation staff added best possible environme.nt for the Division. brightly colored banners, music, their services, and the Grounds rigid control and precise testing Requests for copies may be made games, prizes a.11d 1'0freshments. Maintenance crew trimmed trees essential to clinical research. by calling the Resear<:h Documen­ As each person entered the car­ and sprayed insecticides around t he The Miami center is one of 88 tation Section, Ext. 67543. nival grounds he registered at a carnival grounds. general clinical research centers booth and received a book of tick­ The D.C. Shriners provided all now in operation t;hroughout the ets. Once inside, these tickets could the clowns, except 9-foot-on-stilts country. The centers are funded Two Physiologists Named be used for a tremendous variety Red Tannen w'ho is a member of by the Division of Research Fa­ NIH Grants Associates of games of chance and ski! I. the R& W Hamsters. cilities and Resources of the Na­ tional Institutes of Health and are Dr. Wilford L. Nusser, Professor Volunteers Help generally affiliated with a medical of Physiology and Chairman of the The CC adult and junior Red school. Physiology Department at the Col­ Cross H ospital Volunteers helped lege of Osteopat hic Medicine and to man booths and provided escort Early Diagnosis Possible Surgery, Des Moines, Iowa, has services for wheel chait- patients. "All of the children were born been appointed a Grants Associate Also attending booths were mem­ normal and developed abnormali­ here. bers of the United Presbyterian ties in later life," Dr. Nyhan said. Dr. Nusser received the Ph.D. Youth Council of Bethesda, CC "We know from the repo1ts on two degree from Iowa State College in Normal Volunteer Patients, CC newborns that a diagnosis can be 1958. personnel and admission staffs and made on a basis of high uric acid Dr. Kenneth Surrey, Assistant friends. CC librarians ran "Book levels during the first few hours Plant Physiologist of the Argonne Nook on the Ginza," and refresh­ after bilth. National Laboratory, Argonne, Ill., ments were serv'!d by the CC Nu­ "If we can detect the abnormality since mid-1957, has also joined the trition Department. early, we hope to eliminate brain Grants Associates program for a In addition to the people who damage completely by using drug year of specialized training as volunteered their services, there therapy to control these levels scientist administrator. Not quite sure she should have let were other donations. The Toledo from the first days of life through Dr. Surrey, an alumnus of the he r balloon go, Yvonne O'Bryan, 5 , of Scale Company loaned a 225-pound to the time when fue brain can no University of Punjab, Lahore, re­ scale to the weight-guessing booth, Okloma, Ky., sends a message off and the National Zoological Park longer be damaged. ceived the Ph.D. degree from the into space. Her mothe r, Mrs. Chorles "We are now carrying on studies University of Missouri in 1957. provided the racing tuitles. O'Bryan offe rs a word af c omfort Because everybody got into the on patients from all parts of the while Greg Parsons, 3, and his mother, United States," Dr. Nyhan con­ act, this carnival went the way all drome and is not observed in other Mrs. H. Roy C. Parsons of Buffalo, carnivals should-successfully. tinued. "We are particularly in­ childhood diseases," DI'. Nyhan ex­ W.Va. (left) look on. Both children terested in information on, or re­ plained. "Parents who observe such are CC patie nts. Be hind the counte r fenal of, patients with symptoms behavior in their childl'en should Bob Kohler of Bethesda, o United Despite popular belief to the of this syndrome. seek medical advice as soon as pos­ Presbyterian Youth Council volunteer, contrary, poisonous snakebites are "Self-destructive behavior is an sible since drug therapy is most concentrates on getting the message more dangerous in older people essential diagnostic clue since this effective during the earliest stages right for his "ba llooning mai l serv· than in children, according to a is a prime symptom of the syn- of the disease." ice."-Phatos by Tom Joy. recent NIH study.-U.S. Medicine. THE NIH RECORD August 23, 1966 Page 7

Dr. Philip Elected Head Blood Bank Report Updated NIH Scientists Are Participating in the Of Tick Disease Panel The Clinical Center Blood 11th Pacific Science Congress in Tokyo Dr. Cornelius B. Philip, entomol­ Bank reports that 181 units ogist of the National Institute of of blood were received from A number of NIH scientists are participating in the 11th Pacific Allergy and Infectious Diseases, NIH donors in July. During Science Congress in Tokyo, Japan. The series of symposia which opened has been elected Chairman of the the same period CC patients yesterday will continue through Sept. 10. Food and Agrfoulture Organiza­ received 1,680 units of blood. Dr. Cornelius B. Philip, entomologist at the National Institute of ti:m's Expert Panel One NIH staff member, Vic­ Allergy and Infectious Diseases' on Tick-Borne Dis­ tor M. Held, Division of Re­ Rocky Mountain Laboratory, Ham­ ing papers this week at symposia eases of Livestock. search Grants, joined the "gal­ ilton, Mont., will be chairman of a on filariasis and on soil-trans­ He succeeds Dr. lon-donor club." symposium on tsutsugamushi dis­ mitted helminths. Harry Hoogstraal ease (scrub typhus) to be held Two other NIAID scientists, of the Naval Medi­ Sept. 4-7 at the University of Nii­ Drs. Leon Rosen, Head of the P a­ sored by F AO and the Interna­ gata Medical School. He is also to cal Research Unit tional Office of Epizootics, with cific Research Section, Laboratory (NAM R U-3) in present a paper on rickettsial of Infectious Diseases, and Paul P. headquarters in Paris. disease. Cairo, United Arab Six panel members and four of­ Weinstein, Laboratory of Parasitic Republic, f01· a 4- Dr. J. Allen Scott, Assistant Diseases, are among the United ficial observers attended the meet­ Chief of the Parasitology and Med­ year term as chair- ing to review progress and States members of the panel on Dr. Philip ical Entomology Branch, NIAID parasitology and are also attending man. problems in t he field, including extramural programs, is present- symposia of the Congress. Dr. Philip is a member of the resistance of ticks to insecticides, NIAID scientists attending Con­ tick control with ixodicides, toxi­ scientific staff of the NIAID's gress symposia as observers are Rocky Mountain Laboratory at cological problems in ixodicides, SUGGESTION Ors. Karl M. J ohnson of the Mid­ and the inter-relationships of ticks, Hamilton, Mont., where the panel (Co>ttiwued fro"' Pago 1) dle America Research Unit, Canal held its third quadrennial meeting domestic animals and human and Zone, Isthmus of Panama, and Aug. 8-15. The meeting was spon- animal diseases. cash awards up to and including $500 for adopted suggestions that Lawrence R. Ash of the Pacific benefit their organizations be dele­ Researcfu Section, Laboratory of Ways DRMP May Bridge Gap Between gated to Institute Directors, Divi­ Infectious Diseases. sion Chiefs and the Executive· Offi­ Papers Presented Science and Service Discussed at Forum cer of NIH. Dr. Jacques May of the Office of For awards up to and including foternational Research's Nutrition Will the increased emphasis by Public Health Service on meeting the $100, further delegations within Section is presenting a paper on problems of medical service divert essential support from the Nation's Institutes and Divisions may be "Child Malnutrition" today at a biomedical research efforts? made to Branch Chiefs or their symposium on Population Growth This was one of the questions discussed at an Extramural Forum, equivalents. and Nutrition. Aug. 9, in the Westwood Bldg. Authority to a p p r o v e cash Dr. Woot-Tsuen Wu Leung, also Approximately 100 extramural Regional Medical Programs," he awards of $501 to $1,000 for of OIR's Nutrition Section, will added. adopted suggestions benefiting NIH present a paper on "Preparation staff members heard Karl Yordy, "This program is dependent upon will remain with the NIH Director. Assistant Chief, Division of Re­ of a Food Composition Table for continued vigorous support of re­ Coordinotors Administer the Far East" on Aug. 25 at a sym­ gional Medical Programs, give re­ search. Its essential purpose is to posium on Malnutrition and Food­ assurances that DRMP is an addi­ explore ways of bridging the gap While 0. L. Grabiner will ad­ minister the overall N[ H Employe Born Disease in the Pacific Area. t.ive, not a competitive, p1·ogram. between science and service. At a symposium to be held on the Suggestion Program, new proced­ Problems Anticipated "It may, in fact, lead to a great­ afternoons of Aug. 23-26 on Popu­ ures call also for I/D Suggestion Mr. Yordy pointed out that the er recognition of the benefits of re­ lation P1·oblems in the Pacific, Dr. search by community hospitals, for Coordinators and for Subordinate main reason for the passage of William J . McGanity of Galveston, example, and to an increase in the Suggestion Coordinators who will Tex., a consultant to the OIR Nu­ Public Law 8!>-239-the Heart Dis­ be responsible for administration ease, Cancer, and Stroke Amend­ applications for research grants." trition Section, will present a pa­ The forum gave extramural staff of the system within their respec­ per on "T ying Together t he Popu­ ments of 1965-is the anticipation tive organizational components. that future increases of knowledge an opportunity to ask questions lation Control and Nutritional De­ about the relatively new DRMP Since the Employe Suggestion mand with Special Emphasis on and techniques through medical re­ System is oriented toward manage­ search will make actual use of grant activities, composition of the the Asian and Far Eastern." regions which have received grants, ment improvement and cost reduc­ these advances more of a problem. and anticipated goals for the par­ tion, care is being taken to appoint Dr. Kominz Atte nds "The growth of great cCTiters of ticipating medical centers, clinical as Suggestion Coordinators those Dr. David R. Kominz, Chief of research and teaching, reflecting research centers, hospitals and who are organizationally in a posi­ the OIR Pacific Office, will also at­ in large measure the impact of NIH other groups comprising the re­ tion to give maximum support to tend the Congress. exttamural programs, underlies gional medical programs. line management in the considera­ Representing the Division of tion, adoption and installation of Biologics Standards at ~e Pacific worthwhile suggestions. Congress will be Dt·. Leon J acobs, All employes are urged to sub­ Assistant Director of DBS who mit suggestions, and are reminded will present a paper on the "Trans­ of the cumulative value of rela­ mission of Toxoplasma egondii." tively simple ideas which result in Dr. John C. Feeley, Chlef of the only moderate savings. Bacterial Vaccines Section, Labora­ tory of Bacterial Products, DBS, Success Forecast will present a paper on "Labora­ It is felt that the Suggestion tory Evaluation of Cholera Vac­ System will be a success because cines," which he co-authored with of many modest cash awards Dr. Margaret Pittm.an, Chief of throughout the year, plus a few the LPB, and Charles 0. Roberts, large cash awards. also of LPB. To give further impetus to the Dr. Yoshio Sato, Chief of the Employe Suggestion System, all Section on Steroids, Laboratory of awards, regardless of size, will be Chemistry, National Institute of Participants in the Extramural Forum at the Westwood Building Aug. 9 hear publicized in the NIH R ec01·d. Arthritis and Metabolic Diseases, Assistant Chief Karl Yordy of DRMP discuss "Regional Medical Programs: Suggestions should be submitted will also pat-ticipate in the Science Implications far Science Support." At Mr. Yordy's right is Dr. Gilbe rt Woodside, on HEW F orm 170 to the Sug­ Congress and present a paper en­ Assistant Scientific Directar for Extramural Programs, NICHD, who chaired the gestion Coordinator for an em­ titled "St:eroidal Alkaloids of So­ forum. The extramural forums ere sponsored by the Committee on Staff ploye's area or through his super­ lanum Congestisflorum and Their Training, Extramural Programs, NIH.-Phota by Tom Joy. visor. Biogenetic Significance." Page 8 August 23, 1966 THE NIH RECORD NIAMD Will Staff the Dr. Vincent P. Collins Is First Research Unit in A PHS Indian Hospital Principal Consultant on First research unit to be in­ Radiology for NIGMS corporated into a Public Health Service Indian hospital of the De­ Dr. Vincent P. Collins, Chair­ partment of Health, Education, and man of the Depar tment of Radiol­ Welfare, will be a 25-bed unit de­ ogy at Baylor University, Houston, signed and staffed by the National Tex., was recently named _principal Institute of Arthritis and Metabolic consultant in radiology for the Diseases in the proposed new Phoe­ National Institute nix Medical Center in Arizona, ac­ of General Medical cording to an announcement made Sciences. recently by Dr. E. S. Rabeau, Chief Dr. Frederick L. of the PHS Division of Indian Stone, Director of Health. NJGMS, said that The 200-bed center, says Dr. Ra­ Dr. Collins will s p e n d one year beau, will be a referral facility SUMMER LAB ASSISTANTS-Nine high school science stude nts are spe nding providing diagnostic services and with the Institute 8 weeks af the ir summe r vacation os research assistant$ in the Rocky Moun­ to provide advice specialized treatment for 10 peri­ tain Laboratory, Hamilton, Mont., a facility of the National Institute of pheral hospitals and 7 health cen­ and assistance in Alle rgy and Infectious Diseases. Chose n from a number of candidates and developing its radi­ Pr. Collins ters in Arizona and Nevada, and supported during the 8 weeks by the Montana Division, American Cancer 25 satellite clinics in Arizona, Ne­ ological research and research Society, the youngste rs help out in various laboratories to gain firsthand training programs. vada, California and Utah that knowledge of biome dical research a nd caree r opportunities in the field. From serve Indian tribes of those States. Dr. Collins will help define, in­ left: Dr. H. G. Stoenne r, RML Director, Lawre nce Shorthill of Livingston, sofar as feasible, national goals Decision to place a research unit Moira Davis of Butte, Pame la Burgett of Scobey, Kathleen McCaslin of Butte, in the Phoen1x hospital results for a general radiology program Mitzi Kolar of Geyser, Janice Bartle of Billings, Julie Follansbee of Eure ka, and will serve as liaison in this from recent studies showing that Stephen Larson of Chinook and Gayle Muenchow of Libby. Pima Indians of the nearby Gila field between NIGMS, the Office of River Reservation have the hlghest the NIH Director and other insti­ rate of diabetes of any population tutes here. on record. For the past 14 years, Dr. Col­ lins has been an associate of D1·. History of Med. Society Michael E . DeBakey, internation­ ally known surgeon at Baylor. At Plans Meeting at NLM present, Dr. Collins holds concur­ Thursday, Sept. 22, at 8 p.m. in rent appointments as Radiologist­ the Billings auditorium of the Na­ in"Chief at Ben Taub Hospital and tional Library of Medicine, the Senior Attending Radiologist at Washington Society for the History Methodist Hospital in Houston. of Medicine will hold its first meet­ He also is Chief Consultant in Radiology at the Veterans Hospital ing of the current year. The two talks on the program and a radiological consultant at are: "Some British Origins of St. Luke's and Texas Children's American Medical Ethics" by Dr. Hospitals in Houston. Chester Burns, Fellow, Institute of Dr. Collins holds degrees in both medicine and law. He received his the History of Medicine, Johns M.D. from the University of Toron­ Hopkins School of Medicine, and "First American Medical Societies" to in 1937 and his LL.B. from the University of Houston in 1964. by Dr. J ohn B. Blake, Chief, Medi­ cal History Branch, NLM. He has published 55 papers on A pleasant aspect of summer at the Clinical Center is that it brings back medical research in various medi­ An affiliate of the American As­ Junior Red Cross Volunteers. About 35, nearly all girls, are now se rving. They sociation for the History of Medi­ cal and scientific journals and is ore particularly we lcomed by children patients who participate in occupationa l a member of 26 honorary and pro­ cine, the Society was formed in thera py in the CC's Rehabilitation Department. He re, admiring a sewing ma­ fessional societies. 1961 and holds meetings bi-monthly chine that really works far delighted little girl patients, o re (I to r) Susan except during June, July and Au­ Linn, Dia ne Coston, and Lindo Heogen.-Photo by Ed Hubba rd. gust. Annual dues for membership Appalachia Health Ctr. are $2. Gets 1st Federal Grant Dr. Osborne Is in Charge All Over 40 Offered Exam by D.C. Health Dept. The first Federal grant to help The D.C. Department of Public indicates that you should see your pay the cost of personnel who staff Of Alien Medical Exams Health offers free health examina­ doctor, a Jetter to this effect will community mental health centers Appointment of Dr. Arthur S. tions to anyone age 40 or over , be sent to you. Your doctor or clinic was announced recently by J ohn W. Osborne as Chief of the Foreign without restrictions as to income or will receive a report of your tests. Gardner, Secretary of DHEW. The Operations Branch of the Division place of residence. The tests made An appointment to schedule an $191,055 grant was awarded to the of Foreign Quarantine, U.S. Public are for common diseases which fre­ examination may be made by call­ Appalachia Communit y H e a I t h Health Service, was announced re­ quently occur after age 40. ing DI 7-1834, Ext. 27. The exam­ Center, Inc., Elkins, W.Va. cently by Dr. Louis Jacobs, Chief The examination takes only 30 inations are made at The South­ With the assistance of the Fed­ of the Division. minutes and includes the following west Health Center, Delaware Ave. eral staffing aid, authorized by Con­ Dr. Osborne has been medical tests: and I St., S.W., and/or The Mobile gress last year in an amendment officer in charge of the London Of­ An EKG (electrocardiogram) for Health Unit, Seventh St. and to the Community Mental Health fice of the Service's Division of heart disease, a glaucoma test (for Massachusetts Ave., N.W. Centers Act, the new mental health Foreign Quarantine. eye disease), a chest X-ray for tu­ NIH employes and staff members center will bring a range of psy­ In his new position, Dr. Osborne berculosis or other chest diseases, who have not had these tests re­ chiatric services to an 8-county de­ will be responsible for the alien eyesight and hearing tests, blood cently are encouraged to avail pressed area of 130,000 residents. medical examination program of tests for diabetes, anemia and other themselves of the opportunity to These include inpatient and out­ the Division at 35 medical exam­ diseases, and height and weight obtain this free service. Adminis­ patient care, emergency services, ination facilities in Europe, Asia, check. trative leave not to exceed t wo partial hospitalization, and consul­ Canada, Mexico, South America You will be notified by letter if hours may be granted for t his tation and education for community and the Caribbean area. all the tests are normal. If a test purpose. agencies and professionals.