DOCSLIB.ORG

Frontiers in Biosciences

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Frontiers in Biosciences Proceedings of Telangana Academy of Sciences TAS Special Issue Vol.2, Issue 1, 2020 Frontiers in Biosciences Guest Editor Prof. Bir Bahadur Emeritus Professor of Botany Kakatiya University, TS., India TAS Telangana Academy of Sciences Executive Council - 2018-2020 Editorial Board Prof. K. Narasimha Reddy President Editor of Publications (Former V.C., M. G Univ., Nalgonda) Dr. S. M. Reddy H.No: 12-13-1126/B-305 Prof. P. VenugopalReddy Vice-President Kalakriti Tarnaka - 500 017, (Dept. of Physics, OU, Hyderabad) [email protected]., Prof.Ch. SanjeevaReddy Vice-President Dr. G.V. Madhava Sharma (Dept. of Chemistry, K.U. Warangal) Chief Scientist, CSIR-IICT, Hyderabad-500 007 [email protected] Dr. S. Chandra Sekhar Hon. Secretary (Director, CSIR-IICT, Hyderabad) Dr.G. Bhanuprakash Reddy Scientist-F, NIN, Hyderabad - 500007 Dr. Y. Purushotham Hon. Treasurer [email protected] (C-MET, Hyderabad) Dr. M. Sujatha Prof. S.M. Reddy Editor of Publications Pr. Scientist, Oil seeds Research, (Dept. of Botany, K.U. Warangal) Hyderabad - 5000030 [email protected] Executive Council Prof D. Prasada Rao Chairman, Indo-US Super Specialty Hospital, Prof. G. Bagyanarayana Hyderabad [email protected] (Former VC, Palamuru University) Dr. G. Bhanuprakash Reddy Prof. V. Malla Reddy H.No.-1-9-30(C-77), National Institute of Nutrition (NIN), Hyderabad Ravindranagar Colony, Road No - 1, Hyderabad - 500 007 Dr. V. Chakravarthi [email protected] (University of Hyderabad, Hyderabad) Dr. G. Madhusudhana Reddy Dr. G. Madhusudhana Reddy Scientist G, DMRL, Hyderabad-500 058 (Outstanding Scientist & Director, DMRL, Hyderabad) gmreddy [email protected] Dr. G. Sundararajan Dr. G Parthasarathy (IIT-Madras, Hyderabad) Chief Scientist, NGRI, Hyderabad - 500 007 [email protected] Dr. G. Parthasarathy (NGRI, Hyderabad) Prof. M. Ghanashyam Krishna School of Physics, UOH, Hyderabad - 500 046 Dr. K. Jeevan Rao [email protected] (PJTSAU, Hyderabad) Prof Bir Bahadur Prof. K. Janardhan Reddy The Odyssey 4a, 10-2-289/46, (Dept. of Botany, OU, Hyderabad) Shanthinagar, Masab Tank, Hyderabad - 500 028 [email protected] Dr.R.B.N. Prasad Ex-Officio Members Chief Scientist, IIct Hyderabad - 500007 [email protected] Dr. Ch. Mohan Rao (Former Director, CSIR-CCMB, Hyderabad) Dr. B. Sri Padmavati Professor, Principal Secretary School of Mathematic & Statistics, University of (Higher Education Dept. Govt. of Telangana) Hydebad, Gachinowli, Hyderabad - 500046. Email: [email protected] Telangana Academy of Sciences Regional Coordinators Hyderabad & Ranga Reddy Karimnagar & Adilabad Nizamabad & Medak Prof. K. Janardhan Reddy Prof. M.Vithal Dr. Y. Purushotham H.No.11-14- 234/B3, Road No.11, Dept. of Chemistry, Scientist 'D' C- MET, Hyderabad-051 Haripriya Colony, Saroornagar, Hyderabad-500 035. Osmania University, Hyderabad-500 007 [email protected] [email protected] [email protected] Warangal & Khammam Nalgonda & Mahboobnagar Prof. S. M. Reddy Dr. G. Bhanuprakash Reddy H.No: 12-13-1126/B-305 Kalakruti, Tarnaka - 500017, Scientist-F, NIN, Hyderabad - 500007 [email protected] geereddy @yahoo.com FOREWORD The Telangana Academy of Sciences has been engaged in the Science popularization activities including Publications, Journals, Special Issues on different occasions. The recent publication activities include “Diabesity: The Unacknowledged Indian Knowledge”, “Jivanayanam lo Rasayanalu“ and“21st Century Noble Awards in Chemistry”. As a part of its continued efforts in this direction, the Proceedings of the Telangana Academy of Sciences entitled '' Frontiers in Biosciences " has been brought out . This Proceedings covers diverse topics in frontline areas of Biosciences like Virus Resistant Transgenics; RNA interference as a novel tool for Engineering fungal resistance in crop plants, to name a few,with authors drawn from different institutes and universities of repute. I hope this Proceedings will serve as a pace setter for detailed investigations in Biosciences and be beneficial for the budding researchers in the field. I appreciate efforts made by Prof. BirBahadur, Guest Editor, for bringing out such an informative Proceedings. I thank the Executive Council and the Editor of Publications for their sincere efforts in bringing outthis Proceedings . S. Chandrasekhar Hon. Secretary, TAS From the Guest Editor It gives me pleasure to bring out this Special Issue of the Proceedings of Telangana Academy of Sciences. (Biological Sciences), which includes articles by eminent and senior Botanists as well as a promising young botanist. This issue contains an array of topics of current interest that hopefully will appeal to researchers in the field of Biology &in particular to botany and allied subjects. I take this opportunity to thank all the contributing authors for sharing their knowledge with others. I thank all the reviewers for sparing their precious time for valuable constructive comments and suggestions. Prof. Bir Bahadur Guest Editor From The Editor of Publications Telangana Academy of Sciences (TAS) which has a glorious past of about sixty years, has been active by undertaking a variety of scientific publications of high standard. It also publisheda quarterly journal covering different vital areas of life sciences, chemical, physical ,engineering, earth sciences and mathematics. On the occasion of its Golden Jubilee it has undertaken special Proceedings in different disciplines by inviting articles from eminent scientists in the respective fields. The academy also started a quarterly Newsletter highlighting the activities of the Academy, scientific accomplishments of Fellows and scientific information of special importance. Inspite of a vast community of scientists and significant contributions, technological advancement of public utility could not be made. Further, younger generation of science need to be encouraged and motivated towards scientific developments taking place around the world. The Academy is making sincere efforts to harvest scientific knowledge of illustrious Fellows of the Academy and create a congenial atmosphere for the scientific pursuits. The Academy is also organizing seminars to activate younger generation and involve scientific discussions and attract the young minds to innovations. In this direction, the Academy also initiatedonline publications to reach many more people. The Proceedings in Life Sciences is one such initiative. Prof. Bir Bahadur was requested to be a Guest Editor who could motivate many eminent persons in different areas of Life Sciences. He has taken a keen interest in shaping the Proceedings, The Academy acknowledges the efforts made by Prof. Bir Bahadur S.M. Reddy Editor of Publications, TAS Frontiers in Biosciences Contents 1). RNA interference as a novel tool for Engineering fungal resistance in crop plants M.V. Rajam and Sambhavana Chauhan 1 2). A Review on Virus Resistant Transgenic M. Sujatha, Singareddy Vasavi, N. Srinivasan and Sankaranen Chander Rao 16 3). Natural Food Colours: To Make food more colourful and healthier P. Giridhar and S. Sravan Kumar 45 4). Establishment of phytocoenoses on coal mine over burden of Pranahita-Godavari basin, Telangana M.N.V. Prasad and Sateesh Suthari 54 5). Probiotics – Potential Health Benefactors – A Review S. Ram Reddy, G. Renuka, P. Pallavi and S.M. Reddy 70 6). Ecofriendly Plant Growth Promoting Rhizobacteria for Crop Improvement C. Manoharachary and D. Nagaraju 93 7). Cancer Stem cells: Bench to bedside Geeta K Vemuganti, M. Radhika, Revula VL Narayana and Varsha Prabhu 113 8). Lactate, mitochondria and cancer cell V. Lakshmipathi and Ch. Padmavati 135 9). Evolving Genome Technology and Human Health Y. R. Ahuja and Jehan Zeenath 147 10). Crispr/Cas9 – A Versatile Tool for Genome Engineering S. Ram Reddy, P. Pavan Kumar, N. Kishore, V. Praveen Kumar and Bir Bahadur. 164 11). Helicase-primase interactions in eubacteria : diverse sequences and unified structures Dhakaram Pangeni Sharma, Samudrala Gourinath 195 The Special Issue of The Proceedings of Telangana Academy of Sciences, Frontiers in Biosciences Vol. 02, No.01, 2020, 1-15 RNA INTERFERENCE AS A NOVEL TOOL FOR ENGINEERING FUNGAL RESISTANCE IN CROP PLANTS Sambhavana Chauhan and Manchikatla Venkat Rajam* Department of Genetics, University of Delhi South Campus, Benito Juarez Marg, New Delhi 110021 ABSTRACT The phytopathogenic fungi such as Alternaria, Phytopthora, Magnaporthae, Fusarium, and others cause immense loss of crop productivity. Therefore, plant disease management is very important to control the yield losses in various crop plants, and the preventive measures include the use of agro-chemicals, biological agents and transgenic crops. Although, transgenic technology is a promising one for more than a decade for developing fungal resistant plants, but so far no transgenic crop has been commercialized. Hence, there is an urgent need for novel alternative methods for the control of pathogens and RNA interference (RNAi) is one such method (siRNA, miRNA and artificial miRNA based approaches). More recently, genome editing tool based on CRISPR-Cas9 system has also proven to be a potent alternative for disease control. RNAi-mediated disease control involves the silencing of a vital gene of the target fungal pathogen through host induced gene silencing (HIGS) by expression of dsRNA specific to fungal target gene. This short review covers the basic biology of RNA silencing and the developments in RNAi-mediated control of plant fungal pathogens. CORRESPONDING AUTHOR:
Load more

Recommended publications
  • A Compilation and Analysis of Food Plants Utilization of Sri Lankan Butterfly Larvae (Papilionoidea)
    MAJOR ARTICLE TAPROBANICA, ISSN 1800–427X. August, 2014. Vol. 06, No. 02: pp. 110–131, pls. 12, 13. © Research Center for Climate Change, University of Indonesia, Depok, Indonesia & Taprobanica Private Limited, Homagama, Sri Lanka http://www.sljol.info/index.php/tapro A COMPILATION AND ANALYSIS OF FOOD PLANTS UTILIZATION OF SRI LANKAN BUTTERFLY LARVAE (PAPILIONOIDEA) Section Editors: Jeffrey Miller & James L. Reveal Submitted: 08 Dec. 2013, Accepted: 15 Mar. 2014 H. D. Jayasinghe1,2, S. S. Rajapaksha1, C. de Alwis1 1Butterfly Conservation Society of Sri Lanka, 762/A, Yatihena, Malwana, Sri Lanka 2 E-mail: [email protected] Abstract Larval food plants (LFPs) of Sri Lankan butterflies are poorly documented in the historical literature and there is a great need to identify LFPs in conservation perspectives. Therefore, the current study was designed and carried out during the past decade. A list of LFPs for 207 butterfly species (Super family Papilionoidea) of Sri Lanka is presented based on local studies and includes 785 plant-butterfly combinations and 480 plant species. Many of these combinations are reported for the first time in Sri Lanka. The impact of introducing new plants on the dynamics of abundance and distribution of butterflies, the possibility of butterflies being pests on crops, and observations of LFPs of rare butterfly species, are discussed. This information is crucial for the conservation management of the butterfly fauna in Sri Lanka. Key words: conservation, crops, larval food plants (LFPs), pests, plant-butterfly combination. Introduction Butterflies go through complete metamorphosis 1949). As all herbivorous insects show some and have two stages of food consumtion.
    [Show full text]
  • Characterization of Some Common Members of the Family Malvaceae S.S
    Indian Journal of Plant Sciences ISSN: 2319–3824(Online) An Open Access, Online International Journal Available at http://www.cibtech.org/jps.htm 2014 Vol. 3 (3) July-September, pp.79-86/Naskar and Mandal Research Article CHARACTERIZATION OF SOME COMMON MEMBERS OF THE FAMILY MALVACEAE S.S. ON THE BASIS OF MORPHOLOGY OF SELECTIVE ATTRIBUTES: EPICALYX, STAMINAL TUBE, STIGMATIC HEAD AND TRICHOME *Saikat Naskar and Rabindranath Mandal Department of Botany, Barasat Govt. College, Barasat, Kolkata- 700124, West Bengal, India *Author for Correspondence: [email protected] ABSTRACT Epicalyx, staminal tube, stigma and trichome morphological characters have been used to characterize some common members of Malvaceae s.s. These characters have been analyzed following a recent molecular phylogenetic classification of Malvaceae s.s. Stigmatic character is effective for segregation of the tribe Gossypieae from other tribes. But precise distinction of other two studied tribes, viz. Hibisceae and Malveae on the basis of this character proved to be insufficient. Absence of epicalyx in Malachra has indicated an independent evolutionary event within Hibisceae. Distinct H-shaped trichome of Malvastrum has pointed out its isolated position within Malveae. Staminal tube morphological similarities of Abutilon and Sida have suggested their closeness. A key to the genera has been provided for identification purpose. Keywords: Malvaceae s.s., Epicalyx, Staminal Tube, Stigma, Trichome INTRODUCTION Epicalyx and monadelphous stamens are considered as key characters of the family Malvaceae s.s. Epicalyx was recognized as an important character for taxonomic value by several authors (Fryxell, 1988; Esteves, 2000) since its presence or absence was employed to determine phylogenetic interpretation within the tribes of Malvaceae s.s.
    [Show full text]
  • Apch 2017 Delegates' Abstract
    APCH 2017 DELEGATES’ ABSTRACT Topic: Basic Science: Genetics, genomics, proteomics and metabolomics Abstract No: 3630 A PILOT GENOME WIDE ASSOCIATION STUDY (GWAS) IN MULTI ETHNIC POPULATION OF MALAYSIA Ms Syahirah Kaja Mohideen*1 ; Prof Datuk Dr A Rahman A Jamal1 ; Prof Dr Nor Azmi Kamaruddin1 ; Prof Dr Norlela Sukor1 ; Ms Elena Aisha Azizan1 1MEDICINE/ UNIVERSITI KEBANGSAAN MALAYSIA (UKM)/ Malaysia Objective Primary aldosteronism (PA) occurs due to the presence of aldosterone-producing lesions commonly located in the adrenal gland which can thus be cured by an adrenalectomy. Studies on surgically removed tissues found somatic mutations in five genes (KCNJ5, ATP1A1, ATP2B3, CACNA1D, and CTNNB1) can cause the excess aldosterone production. Most of these studies were performed in Caucasian patients. The aim of our study is to understand the genetic background which may promote somatic mutation in these genes and to investigate the frequency and distribution of these somatic mutations in the multiethnic Asian population in Malaysia. Method To characterize the genetic background of PA, a pilot genome wide association study (GWAS) was performed using the Human Infinium OmniExpressExome-8 v1.4 BeadChip containing 960,919 markers to compare gDNA of PA patients with healthy controls. The Association Workflow in Partek® Genomics SuiteTM was used for quality control and association analysis was performed using the Chi-square Test and reported as an odds ratio (OR). On tumour DNA, targeted sequencing of hotspots for the five causal genes were performed. Discussion From the pilot GWAS, two SNPs in chromosome 2 were identified to be associated with PA (OR=11.03, P-value=7.1x10-10, and OR=1.61, P-value=4.0x10-9,).
    [Show full text]
  • Evolutionary Consequences of Dioecy in Angiosperms: the Effects of Breeding System on Speciation and Extinction Rates
    EVOLUTIONARY CONSEQUENCES OF DIOECY IN ANGIOSPERMS: THE EFFECTS OF BREEDING SYSTEM ON SPECIATION AND EXTINCTION RATES by JANA C. HEILBUTH B.Sc, Simon Fraser University, 1996 A THESIS SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY in THE FACULTY OF GRADUATE STUDIES (Department of Zoology) We accept this thesis as conforming to the required standard THE UNIVERSITY OF BRITISH COLUMBIA July 2001 © Jana Heilbuth, 2001 Wednesday, April 25, 2001 UBC Special Collections - Thesis Authorisation Form Page: 1 In presenting this thesis in partial fulfilment of the requirements for an advanced degree at the University of British Columbia, I agree that the Library shall make it freely available for reference and study. I further agree that permission for extensive copying of this thesis for scholarly purposes may be granted by the head of my department or by his or her representatives. It is understood that copying or publication of this thesis for financial gain shall not be allowed without my written permission. The University of British Columbia Vancouver, Canada http://www.library.ubc.ca/spcoll/thesauth.html ABSTRACT Dioecy, the breeding system with male and female function on separate individuals, may affect the ability of a lineage to avoid extinction or speciate. Dioecy is a rare breeding system among the angiosperms (approximately 6% of all flowering plants) while hermaphroditism (having male and female function present within each flower) is predominant. Dioecious angiosperms may be rare because the transitions to dioecy have been recent or because dioecious angiosperms experience decreased diversification rates (speciation minus extinction) compared to plants with other breeding systems.
    [Show full text]
  • Downloaded from Brill.Com10/07/2021 08:53:11AM Via Free Access 130 IAWA Journal, Vol
    IAWA Journal, Vol. 27 (2), 2006: 129–136 WOOD ANATOMY OF CRAIGIA (MALVALES) FROM SOUTHEASTERN YUNNAN, CHINA Steven R. Manchester1, Zhiduan Chen2 and Zhekun Zhou3 SUMMARY Wood anatomy of Craigia W.W. Sm. & W.E. Evans (Malvaceae s.l.), a tree endemic to China and Vietnam, is described in order to provide new characters for assessing its affinities relative to other malvalean genera. Craigia has very low-density wood, with abundant diffuse-in-aggre- gate axial parenchyma and tile cells of the Pterospermum type in the multiseriate rays. Although Craigia is distinct from Tilia by the pres- ence of tile cells, they share the feature of helically thickened vessels – supportive of the sister group status suggested for these two genera by other morphological characters and preliminary molecular data. Although Craigia is well represented in the fossil record based on fruits, we were unable to locate fossil woods corresponding in anatomy to that of the extant genus. Key words: Craigia, Tilia, Malvaceae, wood anatomy, tile cells. INTRODUCTION The genus Craigia is endemic to eastern Asia today, with two species in southern China, one of which also extends into northern Vietnam and southeastern Tibet. The genus was initially placed in Sterculiaceae (Smith & Evans 1921; Hsue 1975), then Tiliaceae (Ren 1989; Ying et al. 1993), and more recently in the broadly circumscribed Malvaceae s.l. (including Sterculiaceae, Tiliaceae, and Bombacaceae) (Judd & Manchester 1997; Alverson et al. 1999; Kubitzki & Bayer 2003). Similarities in pollen morphology and staminodes (Judd & Manchester 1997), and chloroplast gene sequence data (Alverson et al. 1999) have suggested a sister relationship to Tilia.
    [Show full text]
  • The One Hundred Tree Species Prioritized for Planting in the Tropics and Subtropics As Indicated by Database Mining
    The one hundred tree species prioritized for planting in the tropics and subtropics as indicated by database mining Roeland Kindt, Ian K Dawson, Jens-Peter B Lillesø, Alice Muchugi, Fabio Pedercini, James M Roshetko, Meine van Noordwijk, Lars Graudal, Ramni Jamnadass The one hundred tree species prioritized for planting in the tropics and subtropics as indicated by database mining Roeland Kindt, Ian K Dawson, Jens-Peter B Lillesø, Alice Muchugi, Fabio Pedercini, James M Roshetko, Meine van Noordwijk, Lars Graudal, Ramni Jamnadass LIMITED CIRCULATION Correct citation: Kindt R, Dawson IK, Lillesø J-PB, Muchugi A, Pedercini F, Roshetko JM, van Noordwijk M, Graudal L, Jamnadass R. 2021. The one hundred tree species prioritized for planting in the tropics and subtropics as indicated by database mining. Working Paper No. 312. World Agroforestry, Nairobi, Kenya. DOI http://dx.doi.org/10.5716/WP21001.PDF The titles of the Working Paper Series are intended to disseminate provisional results of agroforestry research and practices and to stimulate feedback from the scientific community. Other World Agroforestry publication series include Technical Manuals, Occasional Papers and the Trees for Change Series. Published by World Agroforestry (ICRAF) PO Box 30677, GPO 00100 Nairobi, Kenya Tel: +254(0)20 7224000, via USA +1 650 833 6645 Fax: +254(0)20 7224001, via USA +1 650 833 6646 Email: [email protected] Website: www.worldagroforestry.org © World Agroforestry 2021 Working Paper No. 312 The views expressed in this publication are those of the authors and not necessarily those of World Agroforestry. Articles appearing in this publication series may be quoted or reproduced without charge, provided the source is acknowledged.
    [Show full text]
  • Cytotaxonomy of Malvaceae III. Meiotic Studies of Hibiscus, Abelmoschus , Azanza, Thespesia, Malachra, Urena and Pavonia
    Cytologia 47: 109-116, 1982 Cytotaxonomy of Malvaceae III. Meiotic studies of Hibiscus, Abelmoschus , Azanza, Thespesia, Malachra, Urena and Pavonia Aparna Dasgupta and R. P. Bhatt1 Department of Pharmacy , S. V. Govt. Polytechnic., Bhopal, India Received January 22, 1980 Family Malvaceae includes many familier plants of cultivation notably cotton . Cytological work on economically important plants of this family has received greater attention, though work has also been done on a few wild species by some workers like Youngman (1927), Davie (1933), Skovsted (1935, 1941), Bates (1967), Bates and Blanchard (1970), Hazra and Sharma (1971), Kachecheba (1972), Bhatt and Dasgupta (1976). However, detailed meiotic study has not been done on many genera and species of the family which is necessary to know the type of ploidy and the basic numbers of chromosomes from which the evolution might have progressed . The present investigation includes 15 species belonging to the tribe Hibisceae and Ureneae of the family Malvaceae. The species of the tribe Ureneae are simple polyploids of seven (Skovsted 1935) which has also been noticed in the present work. However, different chromosome numbers have been reported in the tribe Hibisceae. This vast range of chromosome numbers in the tribe especially necessiated the study of chromosome numbers and the ploidy level. This investigation also aimed at understanding the basic chromosome numbers from which the evolution is supposed to have progressed and the evaluation of systematic position of different taxa as understood at present. Out of 15 species studied meiotic study has been done for the first time in Hibis cus vitifolius, H. hirtus, H.
    [Show full text]
  • In Silico Structure-Function, Specificity and Stability Studies of N-Terminal Nucleophile Hydrolase Enzymes
    IN SILICO STRUCTURE-FUNCTION, SPECIFICITY AND STABILITY STUDIES OF N-TERMINAL NUCLEOPHILE HYDROLASE ENZYMES THESIS SUBMITTED TO SAVITRIBAI PHULE PUNE UNIVERSITY FOR THE DEGREE OF DOCTOR OF PHILOSOPHY IN BIOTECHNOLOGY BY PRIYABRATA PANIGRAHI RESEARCH GUIDE Dr. C.G. SURESH DIVISION OF BIOCHEMICAL SCIENCES CSIR-NATIONAL CHEMICAL LABORATORY DR HOMI BHABHA ROAD, PUNE 411008 MAHARASHTRA, INDIA JUNE 2015 DECLARATION BY THE CANDIDATE I hereby declare that the thesis entitled “In silico structure-function, specificity and stability studies of N-terminal nucleophile hydrolase enzymes” submitted by me for the degree of Doctor of Philosophy is the record of work carried out by me during the period from July 2011 to June 2015 under the guidance of Dr. C.G. Suresh, Chief Scientist and has not formed the basis for the award of any degree, diploma, associateship, fellowship, titles in this or any other University or other institution of higher learning. I further declare that the material obtained from other sources has been duly acknowledged in the thesis. Priyabrata Panigrahi Division of Biochemical Sciences CSIR-National Chemical Laboratory Pune - 411 008 June 2015 Acknowledgement This thesis is the end of my journey towards obtaining Ph.D. It would not have been possible to accomplish this without the help, support and encouragement from many people including my well wishers, my friends and colleagues. I would like to express my thanks to everyone who have made this thesis possible and gave me an unforgettable experience. First and foremost, I would like to thank beloved BapDada and Brahmakumaris World Spiritual University for giving me inner strength and willpower to pursue this journey and also their staunch support during tough times.
    [Show full text]
  • Evaluation of the Long-Term Effects of Urena Lobata Root Extracts on Blood Glucose and Hepatic Function of Normal Rabbits
    Journal of Toxicology and Environmental Health Sciences Vol. 3(8) pp. 204-213, August 2011 Available online at http://www.academicjournals.org/JTEHS ISSN 2006-9820 ©2011 Academic Journals Full Length Research Paper Evaluation of the long-term effects of Urena lobata root extracts on blood glucose and hepatic function of normal rabbits Akhere A. OMONKHUA1* and Iyere O. ONOAGBE2 1Department of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Ondo State, Nigeria. 2Department of Biochemistry, University of Benin, Benin City, Nigeria. Accepted 30 June, 2011 Urena lobata is one of the medicinal plants used to treat diabetes in Nigeria. Its hypoglycaemic and anti- diabetic activities have been demonstrated. This study was designed to evaluate the long term effects of daily oral administration of aqueous extracts of U. lobata roots in normal rabbits. Parameters such as body weight, blood glucose and liver function tests were monitored at specific intervals in the serum for 24 weeks, and in the tissue. U. lobata significantly (P<0.05) reduced the body weight and fasting blood sugar of treated rabbits. Indicators of cholestasis, alkaline phosphatase and -glutamyl transferase, as well as serum direct bilirubin concentration, were initially significantly (P<0.05) increased, these parameters returned to the levels of control before the 10th week of monitoring and tissue enzymes were not depleted, suggesting that the initial toxic response was not sustained. Markers of hepatocyte injury; alanine transaminase and aspartate transaminase, were initially slightly elevated but subsequently returned to control levels. U. lobata root had no significant effects on serum total proteins, albumin and globulins. Regulation of dose and frequency of consumption of U.
    [Show full text]
  • Leguminosae (Fabaceae) in Tribal Medicines
    ISSN 2278- 4136 ZDB-Number: 2668735-5 IC Journal No: 8192 Volume 2 Issue 1 Online Available at www.phytojournal.com Journal of Pharmacognosy and Phytochemistry Leguminosae (Fabaceae) in Tribal Medicines Meghendra Sharma1 and Ashwani Kumar2* 1. Department of Science and Technology, Govt of Rajasthan, SATcom office, IGPRS Campus, JLN Marg, Jaipur 302004, India [Email: [email protected]] 2. Department of Botany, University of Rajasthan, Jaipur 302004, India According to Sushruta, no plant in this world is useless. A large number of crude drugs used in Ayurvedic system employ plants of family Fabaceae. The family Fabaceae popularly known as legumes, is the third largest order of seed-plants containing about 600 genera with 12,000 speices. All the three subfamilies of Fabaceae have been given the status of family and hence they will be treated here as distinct families. Details of medicinal plants of these families and their uses are presented here. Keyword: Fabaceae, Acacia, Tribal medicine, Ethnobotany 1. Introduction between and near the tropics and are more Some ethnobotanical work in India was done in abundant in the old than in the New World. The botanical survey of India. The scope, importance family includes the greatest number of Legumes, and methodology of this field have been out lined comparising 400 genera with about 7000 species. by various workers such as Jain (1965), Mitra and It is an extremely important family and its Jain (1991) Kumar (2000) Maheshwari and Singh members yield nutritious food, fiber, shelter, (1984). The ethanobotanical studied were carried valuable medicines and also virulent poisons out in different parts of India by various workers (Datta and Mukherji, 1952).
    [Show full text]
  • Journalofthreatenedtaxa
    OPEN ACCESS The Journal of Threatened Taxa fs dedfcated to bufldfng evfdence for conservafon globally by publfshfng peer-revfewed arfcles onlfne every month at a reasonably rapfd rate at www.threatenedtaxa.org . All arfcles publfshed fn JoTT are regfstered under Creafve Commons Atrfbufon 4.0 Internafonal Lfcense unless otherwfse menfoned. JoTT allows unrestrfcted use of arfcles fn any medfum, reproducfon, and dfstrfbufon by provfdfng adequate credft to the authors and the source of publfcafon. Journal of Threatened Taxa Bufldfng evfdence for conservafon globally www.threatenedtaxa.org ISSN 0974-7907 (Onlfne) | ISSN 0974-7893 (Prfnt) Artfcle Florfstfc dfversfty of Bhfmashankar Wfldlffe Sanctuary, northern Western Ghats, Maharashtra, Indfa Savfta Sanjaykumar Rahangdale & Sanjaykumar Ramlal Rahangdale 26 August 2017 | Vol. 9| No. 8 | Pp. 10493–10527 10.11609/jot. 3074 .9. 8. 10493-10527 For Focus, Scope, Afms, Polfcfes and Gufdelfnes vfsft htp://threatenedtaxa.org/About_JoTT For Arfcle Submfssfon Gufdelfnes vfsft htp://threatenedtaxa.org/Submfssfon_Gufdelfnes For Polfcfes agafnst Scfenffc Mfsconduct vfsft htp://threatenedtaxa.org/JoTT_Polfcy_agafnst_Scfenffc_Mfsconduct For reprfnts contact <[email protected]> Publfsher/Host Partner Threatened Taxa Journal of Threatened Taxa | www.threatenedtaxa.org | 26 August 2017 | 9(8): 10493–10527 Article Floristic diversity of Bhimashankar Wildlife Sanctuary, northern Western Ghats, Maharashtra, India Savita Sanjaykumar Rahangdale 1 & Sanjaykumar Ramlal Rahangdale2 ISSN 0974-7907 (Online) ISSN 0974-7893 (Print) 1 Department of Botany, B.J. Arts, Commerce & Science College, Ale, Pune District, Maharashtra 412411, India 2 Department of Botany, A.W. Arts, Science & Commerce College, Otur, Pune District, Maharashtra 412409, India OPEN ACCESS 1 [email protected], 2 [email protected] (corresponding author) Abstract: Bhimashankar Wildlife Sanctuary (BWS) is located on the crestline of the northern Western Ghats in Pune and Thane districts in Maharashtra State.
    [Show full text]
  • Aisys CS² User's Reference Manual Software Revision 10.X User Responsibility
    Aisys CS² User's Reference Manual Software Revision 10.X User responsibility Datex-Ohmeda, Inc. a General Electric Company, doing business as GE Healthcare. This product will perform in conformity with the description thereof contained in this User’s Reference manual and accompanying labels and/or inserts, when assembled, operated, maintained, and repaired in accordance with the instruction provided. This Product must be checked periodically. A defective Product should not be used. Parts that are broken, missing, plainly worn, distorted, or contaminated should be replaced immediately. Should repair or replacement become necessary, Datex-Ohmeda recommends that a telephonic or written request for service advice be made to the nearest Datex- Ohmeda Customer Service Center. This Product or any of its parts should not be repaired other than in accordance with written instructions provided by Datex-Ohmeda and by Datex-Ohmeda trained personnel. The Product must not be altered without the prior written approval of Datex-Ohmeda. The user of this Product shall have the sole responsibility for any malfunction which results from improper use, faulty maintenance, improper repair, damage, or alteration by anyone other than Datex-Ohmeda. CAUTION U.S. Federal law restricts this device to sale by or on the order of a licensed medical practitioner.Outside the U.S.A., check the local laws for any restriction that may apply. Table of Contents 1 Introduction Intended use .....................................1-2 Indications for use ..............................1-2 General information .............................1-2 Serial numbers .................................1-4 Trademarks ...................................1-5 Symbols used in the manual or on the equipment ........1-6 Symbols used on the equipment ...................1-6 Symbols used on the user interface ................1-9 Typeface conventions used .......................
    [Show full text]