P2RX2 Antibody Cat

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P2RX2 Antibody Cat. No.: 28-261 P2RX2 Antibody Antibody used in WB on Human Jurkat 0.6 ug/ml. Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human P2RX2. TESTED APPLICATIONS: ELISA, IHC, WB P2RX2 antibody can be used for detection of P2RX2 by ELISA at 1:312500. P2RX2 antibody APPLICATIONS: can be used for detection of P2RX2 by western blot at 0.6 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate PREDICTED MOLECULAR 42 kDa, 44 kDa, 49 kDa, 52 kDa, 55 kDa, 45 kDa WEIGHT: October 2, 2021 1 https://www.prosci-inc.com/p2rx2-antibody-28-261.html Properties PURIFICATION: Antibody is purified by protein A chromatography method. CLONALITY: Polyclonal CONJUGATE: Unconjugated PHYSICAL STATE: Liquid Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose. CONCENTRATION: batch dependent For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: P2RX2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. Additional Info OFFICIAL SYMBOL: P2RX2 ALTERNATE NAMES: P2RX2, P2X2, DFNA41 ACCESSION NO.: NP_777361 PROTEIN GI NO.: 28416921 GENE ID: 22953 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand- gated ion channel. Binding to ATP mediates synaptic transmission between neurons and BACKGROUND: from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene. REFERENCES: 1) Barrera, N.P., et al., (2005) J. Biol. Chem. 280 (11), 10759-10765. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. October 2, 2021 2 https://www.prosci-inc.com/p2rx2-antibody-28-261.html.

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Cells Δγ Lineage Choice and Shapes Peripheral Purinergic P2X7
Purinergic P2X7 Receptor Drives T Cell Lineage Choice and Shapes Peripheral δγ Cells This information is current as Michela Frascoli, Jessica Marcandalli, Ursula Schenk and of October 2, 2021. Fabio Grassi J Immunol 2012; 189:174-180; Prepublished online 30 May 2012; doi: 10.4049/jimmunol.1101582 http://www.jimmunol.org/content/189/1/174 Downloaded from Supplementary http://www.jimmunol.org/content/suppl/2012/05/30/jimmunol.110158 Material 2.DC1 http://www.jimmunol.org/ References This article cites 31 articles, 15 of which you can access for free at: http://www.jimmunol.org/content/189/1/174.full#ref-list-1 Why The JI? Submit online. • Rapid Reviews! 30 days* from submission to initial decision • No Triage! Every submission reviewed by practicing scientists by guest on October 2, 2021 • Fast Publication! 4 weeks from acceptance to publication *average Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 2012 by The American Association of Immunologists, Inc. All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. The Journal of Immunology Purinergic P2X7 Receptor Drives T Cell Lineage Choice and Shapes Peripheral gd Cells Michela Frascoli,* Jessica Marcandalli,* Ursula Schenk,*,1 and Fabio Grassi*,† TCR signal strength instructs ab versus gd lineage decision in immature T cells.
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JNEUROSCI.1426-20.2020.Full.Pdf
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netic ho s & P A f u o l d i a o n l r o g u y o Gonzalez, J phonet Audiol 2018, 4:1 J Journal of Phonetics & Audiology DOI: 10.4172/2471-9455.1000136 ISSN: 2471-9455 Mini Review Open Access The Role of Purinergic P2X and P2Y Receptors in Hearing Loss Gonzalez-Gonzalez S * CILcare, Parc Scientifique Agropolis, Montpellier, France *Corresponding Author: Dr Sergio Gonzalez-Gonzalez, CILcare, Parc Scientifique Agropolis, Montpellier, France, E-mail: [email protected] Received date: December 06 2017; Accepted date: December 30, 2017; Published date: January 10, 2018 Copyright: ©2017 Gonzalez SG. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Hearing loss is the most common form of sensorineural impairment, affecting 5.3% of the worldwide human population. Whereas 1 in 500 children is born with hearing disorders, sudden or progressive forms of hearing loss can appear at adult age. However, the physiological and molecular mechanisms involved in this pathological process remain unclear. Interestingly, an increasing number of studies have demonstrated that purinergic receptors could play a key role on hearing disorders and auditory pathway dysfunctions. This mini review summarizes the current data suggesting a key role of purinergic signaling in cochlear hair cell functions and their involvement in progressive hearing loss. Taken together, these studies provide new knowledge in the biochemical and physiological mechanism of purinergic receptors in cochlear cell functions and open the door for the development of new drugs candidates involved in hearing loss treatment.
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