Visionamerica of Birmingham

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VisionAmerica of Birmingham EYE HEALTH PARTNERS OF ALABAMA AND TENNESSEE TRENTON CLEGHERN, OD, FAAO Our Mission Provide the highest quality of medical and surgical eye care available while advocating the cooperative efforts of optometry and ophthalmology through clinical care, education and research. Multi-specialty medical and surgical eye Care No Primary Care Services Medical eye care Cataract and refractive surgery Cornea surgery Retina Oculoplastics Medical and surgical management of glaucoma Neuro-ophthalmology Pediatrics and strabismus Genetic eye disease and electrophysiological testing VisionAmerica of Birmingham Paul Batson, OD Regional Executive Director Jill Helton, OD Assistant Center Director Trenton Cleghern, OD Consultative Optometrist Rod Nowakowski, OD, PhD Genetic Eye Disease and Electrodiagnostics Donald McCurdy, MD Cataract Surgeon Jeff Fuller, MD Retinal Specialist Irene Ludwig, MD Pediatric and Strabismus Surgeon Matthew Albright, MD Cataract and Cornea Surgeon Dale Brown, MD Retina Specialist Kristin Madonia, MD Neuro-ophthalmologist and Oculoplastics Michael Eddins, MD Cataract Surgeon Anterior Segment/General Medical Eye Care Topical/Clear Cornea Cataract Surgery Same Day Cataract Surgery Toric and Presbyopic IOL’s YAG Capsulotomy Laser Trabeculoplasty Laser Peripheral Iridotomy Pterygium Surgery Uveitis Glaucoma Management Cornea Corneal Ulcers Superficial Keratectomy Intacs for Keratoconus Corneal Transplants Descemet Stripping Endothelial Keratoplasty (DSAEK) Oculoplastics Blepharoplasty Ptosis repair Forehead lift Botox Entropian/Ectropian Tumor biopsy/excision Orbital Surgery: ◦ Decompression ◦ Orbital Fractures ◦ Tumors Pediatrics and Strabismus Pediatric Consults Strabismus Surgery ◦ Multiple Muscle Procedures ◦ Repair of Stretched Muscle Scars Refractive Conventional and Custom Treatments All Laser LASIK PRK Intacs Clear Lens Extraction: ◦ Traditional Monofocal IOL ◦ Presbyopic IOL’s Glaucoma Medical glaucoma care SLT/MLT Peripheral Iridotomy MIGS Vitreoretinal Services Focal Laser Pan Retinal Photocaoagulation Intravitreal Injections Laser Treatment of retinal tears/holes Vitrectomy Retinal Detachment Repair Macular Surgery: Macular Pucker, Macular Hole Neuro-Ophthalmology Papilledema Optic Neuritis Optic Atrophy Acute onset Strabismus Neuro-retinitis Genetics Eye Clinic Achromatopsia Albinism — Oculocutaneous Albinism — Ocular Aniridia Autosomal Dominant Optic Atrophy Best Disease Choroideremia Juvenile X-Linked Retinoschisis Leber Hereditary Optic Neuropathy Retinitis Pigmentosa Stargardt Juvenile Macular Dystrophy Diagnostic Technology Extern Experience Examining and managing your own patients Observation and examination with our subspecialties Surgery Observation ◦ In office ◦ Hospital / ASC Increasing your knowledge and performing diagnostic tests If interested, must interview with Dr. Paul Batson. VisionAmerica Thank You for the invitation! Trenton Cleghern, OD, FAAO Paul Batson, OD [email protected] [email protected].

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Genetic Defects of CHM and Visual Acuity Outcome in 24 Choroideremia
www.nature.com/scientificreports OPEN Genetic defects of CHM and visual acuity outcome in 24 choroideremia patients from 16 Japanese families Takaaki Hayashi1,2*, Shuhei Kameya3, Kei Mizobuchi2, Daiki Kubota3, Sachiko Kikuchi3, Kazutoshi Yoshitake4, Atsushi Mizota5, Akira Murakami6, Takeshi Iwata4 & Tadashi Nakano2 Choroideremia (CHM) is an incurable progressive chorioretinal dystrophy. Little is known about the natural disease course of visual acuity in the Japanese population. We aimed to investigate the genetic spectrum of the CHM gene and visual acuity outcomes in 24 CHM patients from 16 Japanese families. We measured decimal best-corrected visual acuity (BCVA) at presentation and follow-up, converted to logMAR units for statistical analysis. Sanger and/or whole-exome sequencing were performed to identify pathogenic CHM variants/deletions. The median age at presentation was 37.0 years (range, 5–76 years). The mean follow-up interval was 8.2 years. BCVA of the better-seeing eye at presentation was signifcantly worsened with increasing age (r = 0.515, p < 0.01), with a high rate of BCVA decline in patients > 40 years old. A Kaplan–Meier survival curve suggested that a BCVA of Snellen equivalent 20/40 at follow-up remains until the ffties. Fourteen pathogenic variants, 6 of which were novel [c.49 + 5G > A, c.116 + 5G > A, p.(Gly176Glu, Glu177Ter), p.Tyr531Ter, an exon 2 deletion, and a 5.0-Mb deletion], were identifed in 15 families. No variant was found in one family only. Our BCVA outcome data are useful for predicting visual prognosis and determining the timing of intervention in Japanese patients with CHM variants.
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Plastics-Roadmap
Oculoplastics Roadmap Idea for New Intern Curriculum Interns should spend at least 1 Friday afternoon in VA Oculoplastics OR; Friday PM is already protected time. Interns should practice 100 simple interrupted stitches and surgeon’s knots in the Wet Lab before PGY2. Lectures (2 hour interactive sessions) Basic Principles of Plastic Surgery and Oculoplastics (Year A = Year B) Trauma Management (Year A: Orbit trauma. Year B: Eyelid trauma.) Eyelid malpositions and dystopias (Year A: Entropion, Ectropion, Ptosis. Year B: spasm, dystonias) Eyelid Lesions: benign and malignant (Year A = Year B) Lacrimal Disorders (Year A: Pediatric. Year B: Adult.) Orbital Disorders (Year A: Acquired. Year B: Congenital.) Core Topics (to be discussed on rotation) Thyroid eye disease management Ptosis evaluation and recommendations Ectropion/entropion management Orbital fracture management Orbit imaging modalities Home Study Topics Orbit anatomy Congenital malformations Surgical steps and instruments Clinical Skills (to be learned on rotation) External photography Lid and orbit measurements Chalazion and lid lesion excisions Punctal plug placement Local anesthetic injection of lids (important for call!) Schirmer Testing, Jones Testing NLD probing/irrigation Canthotomy/cantholysis (in the OR) Directed Reading (residents will read BCSC and article abstracts at home) BCSC Henderson et al. Photographic standards for facial plastic surgery. Arch Facial Plast Surg. 2005. Strazar et al. Minimizing the pain of local anesthesia injection. Plastic and Reconstructive Surgery. 2013. Simon et al. External levator advancement vs Müller’s muscle–conjunctival resection for correction of upper eyelid involutional ptosis. American Journal of Ophthalmology. 2005. Harris and Perez. Anchored flaps in post-Mohs reconstruction of the lower eyelid, cheek, and lateral canthus.
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Online Ophthalmology Curriculum
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Treatment Potential for LCA5-Associated Leber Congenital Amaurosis
Retina Treatment Potential for LCA5-Associated Leber Congenital Amaurosis Katherine E. Uyhazi,1,2 Puya Aravand,1 Brent A. Bell,1 Zhangyong Wei,1 Lanfranco Leo,1 Leona W. Serrano,2 Denise J. Pearson,1,2 Ivan Shpylchak,1 Jennifer Pham,1 Vidyullatha Vasireddy,1 Jean Bennett,1 and Tomas S. Aleman1,2 1Center for Advanced Retinal and Ocular Therapeutics (CAROT) and F.M. Kirby Center for Molecular Ophthalmology, University of Pennsylvania, Philadelphia, PA, USA 2Scheie Eye Institute at The Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, PA, USA Correspondence: Tomas S. Aleman, PURPOSE. To determine the therapeutic window for gene augmentation for Leber congen- Perelman Center for Advanced ital amaurosis (LCA) associated with mutations in LCA5. Medicine, University of Pennsylvania, 3400 Civic Center METHODS. Five patients (ages 6–31) with LCA and biallelic LCA5 mutations underwent Blvd, Philadelphia, PA 19104, USA; an ophthalmic examination including optical coherence tomography (SD-OCT), full-field [email protected]. stimulus testing (FST), and pupillometry. The time course of photoreceptor degeneration in the Lca5gt/gt mouse model and the efficacy of subretinal gene augmentation therapy Received: November 19, 2019 with AAV8-hLCA5 delivered at postnatal day 5 (P5) (early, n = 11 eyes), P15 (mid, n = 14), Accepted: March 16, 2020 = Published: May 19, 2020 and P30 (late, n 13) were assessed using SD-OCT, histologic study, electroretinography (ERG), and pupillometry. Comparisons were made with the human disease. Citation: Uyhazi KE, Aravand P, Bell BA, et al. Treatment potential for RESULTS. Patients with LCA5-LCA showed a maculopathy with detectable outer nuclear LCA5-associated Leber congenital layer (ONL) in the pericentral retina and at least 4 log units of dark-adapted sensitivity amaurosis.
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Oculoplastics/Orbit 2017-2019
Academy MOC Essentials® Practicing Ophthalmologists Curriculum 2017–2019 Oculoplastics and Orbit *** Oculoplastics/Orbit 2 © AAO 2017-2019 Practicing Ophthalmologists Curriculum Disclaimer and Limitation of Liability As a service to its members and American Board of Ophthalmology (ABO) diplomates, the American Academy of Ophthalmology has developed the Practicing Ophthalmologists Curriculum (POC) as a tool for members to prepare for the Maintenance of Certification (MOC) -related examinations. The Academy provides this material for educational purposes only. The POC should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed at obtaining the best results. The physician must make the ultimate judgment about the propriety of the care of a particular patient in light of all the circumstances presented by that patient. The Academy specifically disclaims any and all liability for injury or other damages of any kind, from negligence or otherwise, for any and all claims that may arise out of the use of any information contained herein. References to certain drugs, instruments, and other products in the POC are made for illustrative purposes only and are not intended to constitute an endorsement of such. Such material may include information on applications that are not considered community standard, that reflect indications not included in approved FDA labeling, or that are approved for use only in restricted research settings. The FDA has stated that it is the responsibility of the physician to determine the FDA status of each drug or device he or she wishes to use, and to use them with appropriate patient consent in compliance with applicable law.
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University of Rochester Flaum Eye Institute
University of Rochester Flaum Eye Institute State-of-the-art eye care… it’s available right here in Rochester. No one should live with vision that is less than what it can be. People who have trouble seeing often accept their condition, not knowing that treatment is available — from the simplest of medications and visual tools to state-of-the-art surgical procedures. Now you can easily refer them to the help they need — all at the Flaum Eye Institute at the University of Rochester. See the dierence we can make in your patients’ quality of life. Refer them today to 585-273-EYES. University of Rochester Flaum Eye Institute A world-class team of ophthalmologists, sub- specialists, and researchers, the faculty practice is committed to developing and applying advanced technologies for the preservation, enhancement, and restoration of vision. Working through a unique partnership of academic medicine, private industry, and the community, we are here to serve you and your patients. One phone number for all faculty practice appoint- ments and new centralized systems make the highest quality eye care more accessible than ever before. Working together, our physicians provide a full range of treatment options for the most common to the most complex vision problems. Glaucoma Cataract Macular Degeneration Diabetic Retinopathy Orbital Diseases Low Vision Dry Eye Syndrome Refractive Surgery Optic Neuropathies Corneal Disease Oculoplastics Motility Disorders Comprehensive Eye Care All-important routine eye exams and a wide range of procedures are oered through the Comprehensive Eye Care service. Consultative, diagnostic, and treatment services are all provided for patients with conditions or symptoms common to cataracts, dry eye, glaucoma, and corneal surface disorders.
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Gene Therapy for Inherited Retinal Diseases
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ED Ophthalmology Guidelines
Ophthalmology Guidelines for Family Physicians & the Emergency Department Revised March 2018 Department of Ophthalmology Introduction 1 Referral Guidelines 2 Referral Categories 3 Driving to Ophthalmology Appointments 3 Patients Known to Ophthalmology 4 Contacting Ophthalmology 5 Contacting Winnipeg Ophthalmologists 5 On Call Ophthalmologist in Brandon 7 Contact Details for Retina Specialists 7 Management Guidelines 8 Chemical Injuries 8 Visual Phenomena 10 The Chronic Red Eye 11 The Acute Red Eye 12 Ocular & Peri-Ocular Pain 16 Blurred Vision & Loss of Vision 17 Orbital & Peri-Orbital Swelling 19 Eyelid and Lacrimal Pathology 20 Diplopia 21 Pupils 22 Trauma 23 Speciﬁc Paediatric Ophthalmic Presentations 29 Appendices 30 Triage Guidelines 30 Minimal Standards of Documentation 30 Visual Requirements for Driving 31 Eye Patches and Eye Shields 32 Ophthalmology Guidelines, revised March 2018 Department of Ophthalmology Use of Eye Drops and Eye Ointments 33 Everting the Upper Eyelid 34 Analgesia for Painful Eyes 35 Slit Lamp Basics 36 Using a Tonopen 39 Using an iCare Tonometer 41 Image Gallery 42 Ophthalmology Guidelines, revised March 2018 Department of Ophthalmology Introduction This document has been compiled by the Department of Ophthalmology to assist emergency physicians and family doctors in the management of patients presenting with ophthalmic complaints. It is not intended to be a comprehensive text on ophthalmic emergencies, but rather provide reasonable guidelines for acute management and referral. The ﬁrst sections give advice on how and when to refer patients, how to deal with patients who have perviously been seen by an ophthalmologist, and contact details for the ophthalmologists who take call. The latter half details common presentations, recommendations for management in the Emergency Department and how urgently they should be referred.
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Pathophysiology and Gene Therapy of the Optic Neuropathy in Wolfram Syndrome Jolanta Jagodzinska
Pathophysiology and gene therapy of the optic neuropathy in Wolfram Syndrome Jolanta Jagodzinska To cite this version: Jolanta Jagodzinska. Pathophysiology and gene therapy of the optic neuropathy in Wolfram Syndrome. Human health and pathology. Université Montpellier, 2016. English. NNT : 2016MONTT057. tel-02000983 HAL Id: tel-02000983 https://tel.archives-ouvertes.fr/tel-02000983 Submitted on 1 Feb 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. ! Délivré par l’Université de Montpellier Préparée au sein de l’école doctorale Sciences Chimiques et Biologiques pour la Santé et de l’unité de recherche INSERM U1051 Institut des Neurosciences de Montpellier Spécialité : Neurosciences Présentée par Jolanta JAGODZINSKA Pathophysiology and gene therapy of the optic neuropathy in Wolfram Syndrome Soutenue le 22/12/2016 devant le jury composé de Timothy BARRETT, Pr, University of Birmingham Président Sulev KOKS, Pr, University of Tartu Rapporteur Marisol CORRAL-DEBRINSKI, DR2 CNRS, UPMC Paris 06 Examinateur Benjamin DELPRAT, CR1 INSERM, INM, Montpellier Examinateur Agathe ROUBERTIE, PH, CHRU Montpellier Examinateur Cécile DELETTRE-CRIBAILLET, CR1 INSERM, INM, Montpellier Directeur de thèse Christian HAMEL, Pr, PU-PH, CHRU Montpellier Co-directeur de thèse ACKNOWLEDGEMENTS I would like to express deep gratitude to my research supervisor, Dr Cécile Delettre-Cribaillet for her constant advice, trust, motivation, kindness and patience.
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Characterizing the Natural History of Visual Function in Choroideremia Using Microperimetry and Multimodal Retinal Imaging
Europe PMC Funders Group Author Manuscript Invest Ophthalmol Vis Sci. Author manuscript; available in PMC 2018 March 14. Published in final edited form as: Invest Ophthalmol Vis Sci. 2017 October 01; 58(12): 5575–5583. doi:10.1167/iovs.17-22486. Europe PMC Funders Author Manuscripts Characterizing the Natural History of Visual Function in Choroideremia Using Microperimetry and Multimodal Retinal Imaging Jasleen K. Jolly1,2, Kanmin Xue1,2, Thomas L. Edwards1,2, Markus Groppe1, and Robert E. MacLaren1,2 1Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; Oxford Biomedical Research Centre 2Oxford Eye Hospital, John Radcliffe Hospital, Oxford, United Kingdom Abstract Purpose—Centripetal retinal degeneration in choroideremia (CHM) leads to early visual field restriction and late central vision loss. The latter marks an acute decline in quality of life but visual prognostication remains challenging. We investigated visual function in CHM by correlating best- corrected visual acuity (BCVA), microperimetry and multimodal imaging. Methods—Fifty-six consecutive CHM patients attending Oxford Eye Hospital were examined with BCVA, 10–2 microperimetry, optical coherence tomography, and fundus autofluorescence (AF). Microperimetry was repeated in 21 eyes and analyzed with Bland-Altman. Kaplan-Meier Europe PMC Funders Author Manuscripts survival plots of eyes retaining 20/20 BCVA were created. Intereye symmetry was assessed. Results—Microperimetry coefficient of repeatability was 1.45 dB. Survival analysis showed an indistinguishable pattern between eyes (median survival 39 years). Macular sensitivity showed a similar decline in right and left eyes, with half-lives of 13.6 years. Zonal analysis showed faster decline nasal to the fovea.
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ICO Residency Curriculum 2Nd Edition and Updated Community Eye Health Section
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2018-2019 Curso De Liderazgo
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