, Castle Connolly and ® Fax (718) 270-1946 (718) Fax Fax (718) 270-3840 (718) Fax Phone (718) 270-2430 Phone (718) Phone (718) 270-3215 Phone (718) Muscular Dystrophy Clinic Muscular Dystrophy Center for Neuromuscular Disease Neuromuscular for Center www.downstate.edu/neurology/neuromuscular Our Mission Our comprehensive a providing to are dedicated We care for most advanced and the diagnosis disorders. with neuromuscular individuals Our goals function, enhance optimal pain, restore alleviate are to and their families and help patients quality of life, disease. challenges of neuromuscular deal with the About Us has a long history as Medical Center SUNY Downstate with a strong only academic medical center, Brooklyn's pursuits. on clinical, academic and research focus The Disease is one of the most Neuromuscular for Center the diagnosis, for States United in the centers advanced disease. of neuromuscular treatment and research Disease utilizes a Neuromuscular for The Center optimize multidisciplinaryin order to approach team our patients. Board-certifiedoutcomes for specialists care with patient disease coordinate in neuromuscular orthopedicpulmonologists, physiatrists, surgeons, pain and occupational management specialists, physical social therapists, speech pathologists, psychologists, and orthotics/prostheticsworkers specialists. This specialized quality, results in high teamwork coordinated dignified, and individualized care in a compassionate, patient-centric environment. been nationally recognized have of our doctors Many in America the Best Doctors by the Consumers' Research Council of America for their the Consumers' Council of America for Research outstanding contributions in medicine. (718) 270-2430 Disease Neuromuscular Disorders Neuromuscular for Adults and Children with and Children for Adults Center for Center SUNY Medical Downstate Center Comprehensive Diagnosis and Treatment and Diagnosis Comprehensive Neuromuscular

Center for Neuromuscular Disease University Hospital of Brooklyn 450 Clarkson Avenue, Box 1213 Brooklyn, NY 11203

Call for an Appointment or Additional Information (718) 270-2430

Comprehensive Diagnosis and Treatment for Adults and Children with Neuromuscular Disorders Brooklyn, NY 11203Brooklyn, Medicaid and Managed Care Plans. 450 Clarkson Avenue, Box 1213 Box 450 Clarkson Avenue, University of Brooklyn Hospital We accept most insurance plans, including Medicare, We

of both patients and their families. and muscle diseases dramatically alter the quality of life and muscle diseases dramatically alter respiratory distress, and intractable pain caused by nerverespiratory distress, and intractable pain caused by progressive, and sometimes fatal. Weakness, paralysis, fatal. Weakness, and sometimes progressive, have been identified. Many are debilitating, often are debilitating, Many been identified. have More than 40 different diseases types of neuromuscular muscular atrophy (SMA). muscular atrophy sclerosis (ALS or Lou Gehrig's Disease) and spinal (ALS or Lou Gehrig's Disease) and spinal sclerosis such as amyotrophic lateral such as amyotrophic and motor neuron disease, neuron and motor such as myasthenia gravis; gravis; such as myasthenia muscular junction disorders, muscular dystrophies; neuro- muscular dystrophies; or inherited); myopathies; myopathies; or inherited); neuropathies (either acquired neuropathies of conditions, including of conditions, including encompass a wide range encompass Neuromuscular disordersNeuromuscular Americans, from infancy through adulthood. infancy through from Americans, Each year, neuromuscular disorders strike 1.5disorders neuromuscular strike million Each year,

Neuromuscular Disease? Neuromuscular What Is What Comprehensive Diagnosis and Treatment for Adults and Children with Neuromuscular Disorders ■ Neuromuscular Disorders ■ Comprehensive Diagnosis ■ Neuromuscular consultations ■ Neuromuscular Research Treated at the Center for are useful for symptoms such as: Accurate diagnosis and prompt, appropriate treatment Because of the extensive clinical and basic science Neuromuscular Disease are crucial for minimizing disability and maximizing quality research done at Downstate, we are often able to offer Unexplained Stiffness Pain Tingling of life for individuals with neuromuscular disorders. • • • our patients treatment options not available elsewhere. Numbness Foot Drop Limb Weakness Specialists at the Neuromuscular Center offer compre- • • • Investigative studies related to neuromuscular disorders ◆ hensive workups to achieve accurate diagnosis of Our dedicated electromyography (EMG) laboratory will continue to lead to new treatments and better out- nerve and muscle diseases and utilize state-of-the-art combines the expertise of neurologists specializing in ■ Treatment Options comes for patients. treatment modalities to optimize quality of life. Our clinical neuromuscular disorders with state-of-the-art team members are skilled in the diagnosis and the technology to offer you the latest in electrodiagnosis: Some of our current ongoing research programs medical management of the following disorders: • Oral and Intravenous Medication include clinical trials in the areas of infectious neuropathies, EMG • Intravenous Immunoglobulin (IVIG) inflammatory myopathies and muscular dystrophy. • Amyotrophic Lateral Sclerosis (ALS, or Lou • Gehrig's Disease), Spinal Muscular Atrophies • Nerve Conduction • Therapeutic Plasmapheresis (SMA) and Motor Neuron Disease Studies • Chemodenervation — Botulinum Toxin (BOTOX® • Autonomic Nervous System Disorders • Repetitive and Myobloc®) injections performed under EMG • Brachial and Lumbar Plexopathies Stimulation (electromyography) guidance • Charcot-Marie-Tooth (CMT) and Other • Evoked Potentials • Ancillary Services — Physical and occupational Hereditary Neuropathies (Somatosensory, therapy, speech therapy, comprehensive pain Single fiber EMG is performed Visual and Acoustic management, orthotics • Chronic Inflammatory Demyelinating only at specialized centers such Brain Stem) Polyneuropathy (CIDP) as the Center for Neuromuscular Disease at SUNY Downstate. • Single Fiber Entrapment Neuropathies (Carpal Tunnel, It is considered the best ■ The Muscular Dystrophy • electrophysiologic test for Electromyography Ulnar Neuropathy, Peroneal Neuropathy, Myasthenia Gravis. Association Clinic and Tarsal Tunnel Syndrome) Drs. Maccabee, Anziska and Abrams in the EMG Lab The Muscular Dystrophy Association (MDA) Clinic, under Guillain-Barré Syndrome • the direction of Yaacov Anziska, MD, is sponsored by the ◆ Other technically advanced diagnostic • Hereditary and Acquired Ataxias Muscular Dystrophy Association procedures include: and meets every other week. ■ Center for Neuromuscular • Hereditary Spastic Paraplegia This clinic provides adults and Autonomic Testing • children with comprehensive Disease Physicians Inflammatory Myopathies (Polymyositis, • Quantitative Sensory diagnostic evaluation and treat- Dermatomyositis and Inclusion Body Myositis) • Evaluation ment, including orthotics, physical Charles Abrams, MD Muscular Dystrophies (Facioscapulohumeral (FSH) therapy, occupational therapy Director, Center for Neuromuscular Disease • Transcranial and Lower Associate Professor of Neurology and Dystrophy and Limb-Girdle Dystrophy (LGMD)) • and genetic testing for a variety Spinal Magnetic of neuromuscular diseases. Physiology & Pharmacology • Myasthenia Gravis (MG) and Stimulation (TMS) Some of the diseases followed Lambert-Eaton (LEMS) Paul J. Maccabee, MD • Stabilometry in this clinic include muscular Director, Electromyography Laboratory dystrophy in adults and children • Myopathies (Endocrine, Drug-induced, Metabolic • Spinal Fluid Analysis Professor of Neurology and Mitochondrial) and Cramping (Duchenne, Becker, myotonic, limb-girdle, facioscapulo- • Muscle, Nerve and Skin humeral), inflammatory myopathies (polymyositis, Yaacov Anziska, MD • Myotonic Dystrophy and Myotonic Syndromes Biopsies dermatomyositis, inclusion body myositis), metabolic Director, Muscular Dystrophy Clinic and mitochondrial myopathies, diseases of neuromuscular Neuropathies (Diabetic, Drug-induced, Assistant Professor of Neurology • • Motion Analysis (Human transmission (myasthenia gravis, Lambert-Eaton Inflammatory, Paraproteinemias) Performance Laboratory) State-of-the-art computer technology allows for syndrome), congenital myopathies, hereditary peripheral www.downstate.edu/neurology/neuromuscular • Periodic Paralysis Genetic Counseling and 3-dimensional neuropathies (Charcot-Marie-Tooth disease) and motor • anatomical mapping. neuron disease (amyotrophic lateral sclerosis, spinal Screening Please visit our website for additional information • Post-Polio Syndrome muscular atrophy). about our physicians, staff, facility and services.