RESEARCH ARTICLE Early Life Conditions and Physiological Stress following the Transition to Farming in Central/Southeast Europe: Skeletal Growth Impairment and 6000 Years of Gradual Recovery Alison A. Macintosh1*, Ron Pinhasi2, Jay T. Stock1 1 PAVE Research Group, Division of Biological Anthropology, Department of Archaeology & Anthropology, University of Cambridge, Cambridge, United Kingdom, 2 Earth Institute and School of Archaeology, Newman Building, University College Dublin, Dublin, Ireland *
[email protected] OPEN ACCESS Abstract Citation: Macintosh AA, Pinhasi R, Stock JT (2016) Early Life Conditions and Physiological Stress Early life conditions play an important role in determining adult body size. In particular, child- following the Transition to Farming in Central/ hood malnutrition and disease can elicit growth delays and affect adult body size if severe Southeast Europe: Skeletal Growth Impairment and 6000 Years of Gradual Recovery. PLoS ONE 11(2): or prolonged enough. In the earliest stages of farming, skeletal growth impairment and e0148468. doi:10.1371/journal.pone.0148468 small adult body size are often documented relative to hunter-gatherer groups, though this Editor: Luca Bondioli, Museo Nazionale Preistorico pattern is regionally variable. In Central/Southeast Europe, it is unclear how early life stress, Etnografico 'L. Pigorini', ITALY growth history, and adult body size were impacted by the introduction of agriculture and Received: August 6, 2015 ensuing long-term demographic, social, and behavioral change. The current study assesses this impact through the reconstruction and analysis of mean stature, body mass, Accepted: January 17, 2016 limb proportion indices, and sexual dimorphism among 407 skeletally mature men and Published: February 4, 2016 women from foraging and farming populations spanning the Late Mesolithic through Early Copyright: © 2016 Macintosh et al.