Anti-Hantavirus Monoclonal antibody, Clone S32 (DMAB6475) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Monoclonal Antibody to Hantavirus Seoul Serotype Specificity S32 reacts with an epitope present on the nucleocapsid protein of Hantavirus strain R22 (also called Seoul or SEO) Target Hantavirus Immunogen Nucleocapsid protein of Hantavirus R22 strain Isotype IgG1 Source/Host Mouse Species Reactivity Hantavirus Clone S32 Conjugate Unconjugated Applications ELISA, IF, IHC-Fr Format Hybridoma culture supernatant Size 1 ea Buffer Reconstitute with 1 ml dist. water Preservative None Storage At 2-8℃ BACKGROUND Introduction Hantaviruses are negative sense RNA viruses in the Bunyaviridae family. Humans may be infected with hantaviruses through rodent bites, urine, saliva or contact with rodent waste products. Some hantaviruses cause potentially fatal diseases in humans, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), but others have not been associated with human disease. Human infections of hantaviruses have almost entirely been 45-1 Ramsey Road, Shirley, NY 11967, USA Email:
[email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved linked to human contact with rodent excrement, but recent human-to-human transmission has been reported with the Andes virus in South America. The name hantavirus is derived from the Hantan River area in South Korea, which provided the founding member of the group: Hantaan virus (HTNV), isolated in the late 1970s by Ho-Wang Lee and colleagues. HTNV is one of several hantaviruses that cause HFRS, formerly known as Korean hemorrhagic fever.