DOCSLIB.ORG

Weizmann Magazine, Spring 2021

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Weizmann Magazine, Spring 2021 COVID-19 Research Highlights 15 Updates from the Moross Integrated Cancer Center 24 Q&A with International Board Chair Cathy Beck 34 למדע ויצמן מכון ויצמן למדע 13 46 NEW SCIENTISTS UPDATE ON THE FLAGSHIPS MAGAZINE MAGAZINE WEIZMANN MAGAZINE A publication of the Department of Resource WEIZMANN WEIZMANN Development Healing what ails the Earth The new nerve center for neuroscience EDITORIAL STAFF Prof. Roee Ozeri, Vice President for Resource Development Tamar Levine, Director, Department of Resource 6 15 Development SCIENCE BRIEFS COVER STORY Tamar Morad, Head, Donor Communications Maria Yakhnin, Visual and Digital Production TABLE OF CONTENTS TABLE Yarden Jaron, Visual and Digital Production EDITOR Tamar Morad The vaccines are here, and research abounds COPYEDITOR Sharon Reinheimer 20 SCIENCE FEATURES From the President WRITING STAFF Sandy Cash Jennifer Racz Dear Friends, Dinah Elashvili Anne Sperling The one-year mark of the COVID-19 pandemic has passed Tali Galsky Edward Truitt and here in Israel, where the rate of vaccination is the highest in the world, we are starting to see the light at the end of the With thanks to the Department tunnel. Our thoughts are with our many friends around the of Communications world; this is a network which keeps the Institute strong and The anthropocene is upon us Rx for the ocean thriving. DONOR RECOGNITION Coronavirus-related research on campus is bounding Daphna Freeman ahead, and we expect a range of insights from this virus to play Irit Oz a starring role in fending off future pandemics and broaden- 28 34 Ayelet Rais SPOTLIGHT ON Q&A SCIENCE BRIEFS ing our understanding of the immune system. 2 Discoveries and other news While we were required to pull back on the number of scientists and staff on campus in the last year, it is remark- ILLUSTRATION WEIZMANN WORLD able that unlike many other institutions, Weizmann has Davide Bonazzi 30 Keeping apart, staying together continued to advance its research across all fields. If anything, the pandemic has underscored the importance of science NEW SCIENTISTS GRAPHIC DESIGN in the health of everyone on the planet—and the imperative Alexey Kletsel, Netgo Ltd. Barbara and 10 When hosts become hostages to keep it going strong. Roberto Kaminitz This requires partnerships with world-leading insti- STUDENTS tutions—which you’ll read about here—and partnerships PHOTOGRAPHY AND RENDERINGS 42 A future in plain sight with philanthropists who deeply value science and all that it Bank of Israel Yael Ilan can do for mankind. On that note, I want to call your atten- 40 ART AND SCIENCE Itai Belson, Ohad Herches Liora Kogan tion to a new section in Weizmann Magazine, ‘Updates on the ALUMNI 49 Michael Druks / Zoom Out of the Weizmann Institute Weizmann Institute Flagships,’ which offers sneak previews of the incredible Photo Lab Photo Archives IN MEMORIAM research in our major initiatives. Matt Greenslade Shutterstock 50 Prof. Nir Friedman With all best wishes for a pleasant and healthy spring, Axel Griesch Rami Shlush Q&A with Sincerely, SPRING 2021 SPRING 2021 • • International Lighting up the world Board Chair מכון ויצמן למדע 19 № № 19 of computation Cathy Beck Prof. Alon Chen President, Weizmann Institute of Science Visit us: TOC2 weizmann.ac.il/WeizmannCompass 1 MAGAZINE First stone laid for Vaccination station srael’s COVID-19 vaccina- WEIZMANN André Deloro Building tion campaign has been rolled I out successfully across the Institute, and awards the annual André country, with a higher percentage eizmann management and representatives Deloro Prize to an outstanding scientist of citizens receiving the vaccina- of the Adelis Foundation came together during the International Board. tion than in any country in the world. on March 11 for a moving cornerstone-laying Prof. Dan Yakir of the Department Most Israeli have received their W of Earth and Planetary Sciences, two-shot series through one of the ceremony for the André Deloro Building for Advanced chaired the scientific steering country’s four HMOs. Nevertheless, SCIENCE BRIEFS SCIENCE committee that helped oversee the the Weizmann Institute did its and Intelligent Materials, the planned state-of-the-art specifications and overall design of the share to make sure vaccines were Deloro building. available to its entire community, national HMOs. In late February, yet had a chance to be inoculated with facility that will house the Tom and Mary Beck Center At the ceremony, Weizmann which also includes international the Institute set up a temporary the first dose; another station was set for Advanced and Intelligent Materials. President Prof. Alon Chen presented scientists and students who don’t vaccination station on campus for all up three weeks later, in mid-March, necessarily belong to any of the faculty, students, and staff who hadn’t for second doses. // In attendance were Rebecca Boukhris, Director of the Adelis Foundation, and her husband Sidney Boukhris, also a member of the board of the founda- tion, which was established to realize the vision of the late André Deloro. Deloro, who died in 2012, was born in Cairo and was educated in France. Weizmann and ETH Zürich sign He was a world-class engineer who designed ports, industrial parks, hotels, and large infrastructure cooperation agreement projects throughout the Middle East. He cared deeply about Israel and visionary gift from René and of the European Committee; and Zohar for the ongoing support he has established his foundation with a focus Susanne Braginsky has enabled Menshes, Executive Vice President generously provided to the on advancing social, educational, and A the launch of a formal partner- of the European Committee. Weizmann Institute, but especially scientific causes in Israel. The Adelis ship between the Weizmann Institute Scientists at the ETH and today, for this seminal gift which Foundation has given generously of Science and ETH Zürich, the Swiss at Weizmann have a long tradi- bridges the gap between Zürich to a range of areas at the Weizmann Rendering of the future Deloro Building on campus Federal Institute of Technology, with tion of collaboration, but the recent and Rehovot,” said Mr. Drake. “We funds to be earmarked to joint research gift from René and Susanne Braginksy highly appreciate the ETH as Rebecca and Sidney Boukhris projects between scientists at the two formalizes the relationship and creates a great partner for researching with a scroll of appreciation and, institutions. An online ceremony opportunity for more immediate and together in basic science. May we separately signed a sealed scroll marking the signing of a Memorandum robust joint scientific investigations. continue to flourish and support dedicating the building and of Understanding took place “A very special thanks to our fundamental science for the benefit embedded it in a cornerstone of the on March 1. longtime friend René Braginsky of humanity.” // new facility. In attendance were Mr. Braginsky, “The André Deloro Building who is also a Life Member brings together investigators from of the Weizmann International chemistry and physics and gives them Board; Weizmann President the space and advanced equipment Prof. Alon Chen; ETH President they need to pursue their curiosity,” Joël Mesot; ETH Vice President said Prof. Chen. “That is the Weizmann Prof. Detlef Günther; Bob Drake, vision, shared by Mr. Deloro, who Chairman of the European Committee encouraged curiosity-driven research for the Weizmann Institute and was committed to giving the best of Science and Vice Chairman of the SPRING 2021 people the best possible tools needed International Board of Weizmann; Eric • for world-class research.” // Stupp, Chairman of the Swiss Society of Friends of the Weizmann Institute מכון ויצמן למדע of Science and a member of the 19 № L to R: Rebecca Boukhris, Prof. Alon Chen, Sidney Boukhris Executive Board of Weizmann and René Braginsky 2 3 MAGAZINE Women in science: making inroads WEIZMANN in academia and industry rom its launch in 2007, the Israel National Many of these women are attaining replaced by Prof. Idit Shachar, leadership roles in their fields, evincing a member of the Department Postdoctoral Award Program for Advancing the impact of the program on industry of Immunology. Her newly riefs in Israel. titled role is Head of the B Women in Science at the Weizmann Institute F To highlight this success, the Office for the Advancement set out to increase the number of female scientists Advancing Women in Science Program of Women in Science and Gender cience S launched an online lecture series Equality. in academia in Israel. And it has indeed been highly this year featuring outstanding “Despite the numerous successful, with about 65 percent of its former par- female researchers who have gone challenges we faced over the past on to become prominent players few years, the program continues ticipants—women scientists who have done postdoc in industry. In December, Dr. Michal to make important strides Rosen-Zvi, Director of Healthcare in advancing the careers fellowships abroad—going on to attain faculty-track Informatics at IBM Research of women scientists. I am sure positions in Israeli academia. But there’s another in Haifa and a visiting professor at the that this will continue and grow Hebrew University of Jerusalem, further when Idit Shachar takes unintended success story among the remaining discussed the transformation of health- my place,” said Prof. Addadi. 35 percent: the program alumni who have gone care technologies through artificial “I accepted this appointment intelligence, specifically as relates since I believe that the time is on to careers in Israeli high tech and biotech. to breast cancer research. ripe for the Weizmann Institute— January’s speaker was along with our desire to be Dr. Moran Grossman, who completed excellent in science—to become both her MSc and PhD at the a light house for social issues Weizmann Institute.
Load more

Recommended publications
  • Tsvi Tlusty – C.V
    TSVI TLUSTY – C.V. 06/2021 Center for Soft and Living Matter, Institute for Basic Science, Bldg. (#103), Ulsan National Institute of Science and Technology, 50 UNIST-gil, Ulju-gun, Ulsan 44919, Korea email: [email protected] homepage: life.ibs.re.kr EDUCATION AND EMPLOYMENT 2015– Distinguished Professor, Department of Physics, UNIST, Ulsan 2015– Group Leader, Center for Soft and Living Matter, Institute for Basic Science 2011–2015 Long-term Member, Institute of Advanced Study, Princeton. 2005–2013 Senior researcher, Physics of Complex Systems, Weizmann Institute. 2000–2004 Fellow, Center for Physics and Biology, Rockefeller University, New York. Host: Prof. Albert Libchaber 1995–2000 Ph.D. in Physics, Weizmann Institute, “Universality in Microemulsions”, Supervisor: Prof. Samuel A. Safran. 1991–1995 M.Sc. in Physics, Weizmann Institute. 1988–1990 B.Sc. in Physics and Mathematics (Talpyot), Hebrew University, Jerusalem. Teaching: Landmark Experiments in Biology (2006); Statistical Physics (2007, 2017-20); Information in Biology (2012); Errors and Codes (IAS, 2012); Theory of Living Matter (2016); Students and post-doctoral fellows (03/2020) Pineros William (postdoc, 2019- ) John Mcbride (postdoc, 2018- ) Somya Mani (postdoc, 2018- ) Tamoghna Das (postdoc, 2018- ) Ashwani Tripathi (postdoc, 2018- ) Sandipan Dutta (postdoc, 2016-2021), Prof. at BIRS Pileni, India Vladimir Reinharz (postdoc, 2018-2020), Prof. at U. Montreal. YongSeok Jho (research fellow, 2016-2017), Prof. at GyeongSang U. Yoni Savir (Ph.D., 2005-2011) Prof. at Technion. Adam Lampert (Ph.D., 2008-2012) Prof. at U. Arizona. Arbel Tadmor (M.Sc., 2006-2008) researcher at TRON. Maria Rodriguez Martinez (Postdoc, 2007-2009), PI at IBM Zurich Tamar Friedlander (Postdoc, 2009 -2012) Prof.
    [Show full text]
  • Mechanistic Mathematical Modeling of Spatiotemporal Microtubule Dynamics and Regulation in Vivo
    Research Collection Doctoral Thesis Mechanistic mathematical modeling of spatiotemporal microtubule dynamics and regulation in vivo Author(s): Widmer, Lukas A. Publication Date: 2018 Permanent Link: https://doi.org/10.3929/ethz-b-000328562 Rights / License: In Copyright - Non-Commercial Use Permitted This page was generated automatically upon download from the ETH Zurich Research Collection. For more information please consult the Terms of use. ETH Library diss. eth no. 25588 MECHANISTICMATHEMATICAL MODELINGOFSPATIOTEMPORAL MICROTUBULEDYNAMICSAND REGULATION INVIVO A thesis submitted to attain the degree of DOCTOR OF SCIENCES of ETH ZURICH (dr. sc. eth zurich) presented by LUKASANDREASWIDMER msc. eth cbb born on 11. 03. 1987 citizen of luzern and ruswil lu, switzerland accepted on the recommendation of Prof. Dr. Jörg Stelling, examiner Prof. Dr. Yves Barral, co-examiner Prof. Dr. François Nédélec, co-examiner Prof. Dr. Linda Petzold, co-examiner 2018 Lukas Andreas Widmer Mechanistic mathematical modeling of spatiotemporal microtubule dynamics and regulation in vivo © 2018 ACKNOWLEDGEMENTS We are all much more than the sum of our work, and there is a great many whom I would like to thank for their support and encouragement, without which this thesis would not exist. I would like to thank my supervisor, Prof. Jörg Stelling, for giving me the opportunity to conduct my PhD research in his group. Jörg, you have been a great scientific mentor, and the scientific freedom you give your students is something I enjoyed a lot – you made it possible for me to develop my own theories, and put them to the test. I thank you for the trust you put into me, giving me a challenge to rise up to, and for always having an open door, whether in times of excitement or despair.
    [Show full text]
  • Weizmann Magazine, Spring 2021
    COVID-19 Research Highlights 15 Updates from the Moross Integrated Cancer Center 24 Q&A with International Board Chair Cathy Beck 34 למדע ויצמן מכון ויצמן למדע 13 46 NEW SCIENTISTS UPDATE ON THE FLAGSHIPS MAGAZINE MAGAZINE WEIZMANN MAGAZINE A publication of the Department of Resource WEIZMANN WEIZMANN Development Healing what ails the Earth The new nerve center for neuroscience EDITORIAL STAFF Prof. Roee Ozeri, Vice President for Resource Development Tamar Levine, Director, Department of Resource 6 15 Development SCIENCE BRIEFS COVER STORY Tamar Morad, Head, Donor Communications Maria Yakhnin, Visual and Digital Production TABLE OF CONTENTS TABLE Yarden Jaron, Visual and Digital Production EDITOR Tamar Morad The vaccines are here, and research abounds COPYEDITOR Sharon Reinheimer 20 SCIENCE FEATURES From the President WRITING STAFF Sandy Cash Jennifer Racz Dear Friends, Dinah Elashvili Anne Sperling The one-year mark of the COVID-19 pandemic has passed Tali Galsky Edward Truitt and here in Israel, where the rate of vaccination is the highest in the world, we are starting to see the light at the end of the With thanks to the Department tunnel. Our thoughts are with our many friends around the of Communications world; this is a network which keeps the Institute strong and The anthropocene is upon us Rx for the ocean thriving. DONOR RECOGNITION Coronavirus-related research on campus is bounding Daphna Freeman ahead, and we expect a range of insights from this virus to play Irit Oz a starring role in fending off future pandemics and broaden- 28 34 Ayelet Rais SPOTLIGHT ON Q&A SCIENCE BRIEFS ing our understanding of the immune system.
    [Show full text]
  • Causal Queries from Observational Data in Biological Systems Via Bayesian Networks: an Empirical Study in Small Networks
    Causal Queries from Observational Data in Biological Systems via Bayesian Networks: An Empirical Study in Small Networks Alex White and Matthieu Vignes Abstract Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and post- genomics data sets. Indeed, biological entities are not isolated, but are components of complex multi-level systems. We go one step further and advocate for the con- sideration of causal representations of the interactions in living systems. We present the causal formalism and bring it out in the context of biological networks, when the data is observational. We also discuss its ability to decipher the causal infor- mation flow as observed in gene expression. We also illustrate our exploration by experiments on small simulated networks as well as on a real biological data set. Key words: Causal biological networks, Gene regulatory network reconstruction, Direct Acyclic Graph inference, Bayesian networks 1 Introduction Throughout their lifetime, organisms express their genetic program, i.e. the instruc- tion manual for molecular actions in every cell. The products of the expression of this program are messenger RNA (mRNA); the blueprints to produce proteins, the cornerstones of the living world. The diversity of shapes and the fate of cells is a re- sult of different readings of the genetic material, probably because of environmental factors, but also because of epigenetic organisational capacities. The genetic mate- rial appears regulated to produce what the organism needs in a specific situation. We now have access to rich genomics data sets. We see them as instantaneous images of cell activity from varied angles, through different filters.
    [Show full text]
  • Multiscale Modeling in Systems Biology
    Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 2051 Multiscale Modeling in Systems Biology Methods and Perspectives ADRIEN COULIER ACTA UNIVERSITATIS UPSALIENSIS ISSN 1651-6214 ISBN 978-91-513-1225-5 UPPSALA URN urn:nbn:se:uu:diva-442412 2021 Dissertation presented at Uppsala University to be publicly examined in 2446 ITC, Lägerhyddsvägen 2, Uppsala, Friday, 10 September 2021 at 10:15 for the degree of Doctor of Philosophy. The examination will be conducted in English. Faculty examiner: Professor Mark Chaplain (University of St Andrews). Abstract Coulier, A. 2021. Multiscale Modeling in Systems Biology. Methods and Perspectives. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 2051. 60 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1225-5. In the last decades, mathematical and computational models have become ubiquitous to the field of systems biology. Specifically, the multiscale nature of biological processes makes the design and simulation of such models challenging. In this thesis we offer a perspective on available methods to study and simulate such models and how they can be combined to handle biological processes evolving at different scales. The contribution of this thesis is threefold. First, we introduce Orchestral, a multiscale modular framework to simulate multicellular models. By decoupling intracellular chemical kinetics, cell-cell signaling, and cellular mechanics by means of operator-splitting, it is able to combine existing software into one massively parallel simulation. Its modular structure makes it easy to replace its components, e.g. to adjust the level of modeling details. We demonstrate the scalability of our framework on both high performance clusters and in a cloud environment.
    [Show full text]
  • Advancing a Systems Cell-Free Metabolic Engineering Approach to Natural Product Synthesis and Discovery
    University of Tennessee, Knoxville TRACE: Tennessee Research and Creative Exchange Doctoral Dissertations Graduate School 12-2020 Advancing a systems cell-free metabolic engineering approach to natural product synthesis and discovery Benjamin Mohr University of Tennessee Follow this and additional works at: https://trace.tennessee.edu/utk_graddiss Recommended Citation Mohr, Benjamin, "Advancing a systems cell-free metabolic engineering approach to natural product synthesis and discovery. " PhD diss., University of Tennessee, 2020. https://trace.tennessee.edu/utk_graddiss/6837 This Dissertation is brought to you for free and open access by the Graduate School at TRACE: Tennessee Research and Creative Exchange. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of TRACE: Tennessee Research and Creative Exchange. For more information, please contact [email protected]. To the Graduate Council: I am submitting herewith a dissertation written by Benjamin Mohr entitled "Advancing a systems cell-free metabolic engineering approach to natural product synthesis and discovery." I have examined the final electronic copy of this dissertation for form and content and recommend that it be accepted in partial fulfillment of the equirr ements for the degree of Doctor of Philosophy, with a major in Energy Science and Engineering. Mitchel Doktycz, Major Professor We have read this dissertation and recommend its acceptance: Jennifer Morrell-Falvey, Dale Pelletier, Michael Simpson, Robert Hettich Accepted for the Council: Dixie L. Thompson Vice Provost and Dean of the Graduate School (Original signatures are on file with official studentecor r ds.) Advancing a systems cell-free metabolic engineering approach to natural product synthesis and discovery A Dissertation Presented for the Doctor of Philosophy Degree The University of Tennessee, Knoxville Benjamin Pintz Mohr December 2019 c by Benjamin Pintz Mohr, 2019 All Rights Reserved.
    [Show full text]
  • Weizmann Magazine, Spring 2021
    COVID-19 Research Highlights 14 Updates from the Moross Integrated Cancer Center 24 Q&A with International Board Chair Cathy Beck 34 למדע ויצמן מכון ויצמן למדע 13 46 NEW SCIENTISTS UPDATE ON THE FLAGSHIPS MAGAZINE MAGAZINE WEIZMANN MAGAZINE A publication of the Department of Resource WEIZMANN WEIZMANN Development Healing what ails the Earth The new nerve center for neuroscience EDITORIAL STAFF Prof. Roee Ozeri, Vice President for Resource Development Tamar Levine, Director, Department of Resource 6 14 Development SCIENCE BRIEFS COVER STORY Tamar Morad, Head, Donor Communications Maria Yakhnin, Visual and Digital Production TABLE OF CONTENTS TABLE Yarden Jaron, Visual and Digital Production EDITOR Tamar Morad The vaccines are here, and research abounds From the President COPYEDITOR Dear Friends, Sharon Reinheimer 20 The one-year mark of the COVID-19 pandemic has SCIENCE FEATURES passed and here in Israel, where the rate of vaccination WRITING STAFF is the highest in the world, we are starting to see the Sandy Cash Jennifer Racz light at the end of the tunnel. Our thoughts are with our Dinah Elashvili Anne Sperling many friends around the world; this is a network which Tali Galsky Edward Truitt keeps the Institute strong and thriving. Coronavirus-related research on campus is With thanks to the Department bounding ahead, and we expect a range of insights from of Communications this virus to play a starring role in fending off future The anthropocene is upon us Rx for the ocean pandemics and broadening our understanding of the DONOR RECOGNITION immune system. Daphna Freeman While we were required to pull back on the number Irit Oz of scientists and staff on campus in the last year, it 28 34 Ayelet Rais SPOTLIGHT ON Q&A SCIENCE BRIEFS is remarkable that unlike many other institutions, 2 Discoveries and other news Weizmann has continued to advance its research across all fields.
    [Show full text]
  • Israel Prize
    Year Winner Discipline 1953 Gedaliah Alon Jewish studies 1953 Haim Hazaz literature 1953 Ya'akov Cohen literature 1953 Dina Feitelson-Schur education 1953 Mark Dvorzhetski social science 1953 Lipman Heilprin medical science 1953 Zeev Ben-Zvi sculpture 1953 Shimshon Amitsur exact sciences 1953 Jacob Levitzki exact sciences 1954 Moshe Zvi Segal Jewish studies 1954 Schmuel Hugo Bergmann humanities 1954 David Shimoni literature 1954 Shmuel Yosef Agnon literature 1954 Arthur Biram education 1954 Gad Tedeschi jurisprudence 1954 Franz Ollendorff exact sciences 1954 Michael Zohary life sciences 1954 Shimon Fritz Bodenheimer agriculture 1955 Ödön Pártos music 1955 Ephraim Urbach Jewish studies 1955 Isaac Heinemann Jewish studies 1955 Zalman Shneur literature 1955 Yitzhak Lamdan literature 1955 Michael Fekete exact sciences 1955 Israel Reichart life sciences 1955 Yaakov Ben-Tor life sciences 1955 Akiva Vroman life sciences 1955 Benjamin Shapira medical science 1955 Sara Hestrin-Lerner medical science 1955 Netanel Hochberg agriculture 1956 Zahara Schatz painting and sculpture 1956 Naftali Herz Tur-Sinai Jewish studies 1956 Yigael Yadin Jewish studies 1956 Yehezkel Abramsky Rabbinical literature 1956 Gershon Shufman literature 1956 Miriam Yalan-Shteklis children's literature 1956 Nechama Leibowitz education 1956 Yaakov Talmon social sciences 1956 Avraham HaLevi Frankel exact sciences 1956 Manfred Aschner life sciences 1956 Haim Ernst Wertheimer medicine 1957 Hanna Rovina theatre 1957 Haim Shirman Jewish studies 1957 Yohanan Levi humanities 1957 Yaakov
    [Show full text]
  • Scientific Activities 2002
    Scientific Activities 2002 Rehovot, Israel Edited, Designed and Typeset by Aviva Ovadia Cover Design by Shoshana Zioni, Graphics Department We wish to thank all the secretarial staff who worked on this project, without whose help this publication would not be possible. Printed in Israel By Publishing Department Weizmann Institute of Science ISSN 0083-7849 Contents Board of Governors vii Scientific and Academic Advisory Committee xv Officers of the Weizmann Institute xvii Weizmann Institute of Science xix Faculty of Biochemistry Faculty of Biochemistry - Overview 3 Biological Chemistry 5 Molecular Genetics 13 Plant Sciences 21 Biological Services 27 Avron-Wilstätter Minerva Center for Research in Photosynthesis 29 Y. Leon Benoziyo Institute for Molecular Medicine 31 Dr. Josef Cohn Minerva Center for Biomembrane Research 33 Crown Human Genome Center 35 Mel Dobrin Center for Nutrition 37 Leo and Julia Forchheimer Center for Molecular Genetics 39 Kekst Family Center for Medical Genetics 41 Charles W. and Tillie K. Lubin Center for Plant Biotechnology 43 M.D. Moross Institute for Cancer Research 45 David and Fela Shapell Family Center for Genetic Disorders Research 47 Harry and Jeannette Weinberg Center for Plant Molecular Genetics Research 49 Faculty of Biology Faculty of Biology - Overview 53 Biological Regulation 55 Immunology 61 Molecular Cell Biology 69 Neurobiology 83 Veterinary Resources 89 Helen and Norman Asher Center for Human Brain Imaging 91 Nella and Leon Benoziyo Center for Neurosciences 93 Carl and Micaela Einhorn-Dominic Institute for Brain Research 95 Murray H. and Meyer Grodetsky Center for Research of Higher Brain Functions 97 Robert Koch-Minerva Center for Research in Autoimmune Diseases 99 Belle S.
    [Show full text]
  • Bioengineering Professor Trey Ideker Wins 2009 Overton Prize
    Bioengineering Professor Trey Ideker Wins 2009 Overton Prize March 13, 2009 Daniel Kane University of California, San Diego bioengineering professor Trey Ideker-a network and systems biology pioneer-has won the International Society for Computational Biology's Overton Prize. The Overton prize is awarded each year to an early-to-mid-career scientist who has already made a significant contribution to the field of computational biology. Trey Ideker is an Associate Professor of Bioengineering at UC San Diego's Jacobs School of Engineering, Adjunct Professor of Computer Science, and member of the Moores UCSD Cancer Center. He is a pioneer in using genome-scale measurements to construct network models of cellular processes and disease. His recent research activities include development of software and algorithms for protein network analysis, network-level comparison of pathogens, and genome-scale models of the response to DNA-damaging agents. "Receiving this award is a wonderful honor and helps to confirm that the work we have been doing for the past several years has been useful to people," said Ideker. "This award also provides great recognition to UC San Diego which has fantastic bioinformatics programs both at the undergraduate and graduate level. I could never have done it without the help of some really first-rate bioinformatics and bioengineering graduate students," said Ideker. Ideker is on the faculty of the Jacobs School of Engineering's Department of Bioengineering, which ranks 2nd in the nationfor biomedical engineering, according to the latest US News rankings. The bioengineering department has ranked among the top five programs in the nation every year for the past decade.
    [Show full text]
  • The Myth of Junk DNA
    The Myth of Junk DNA JoATN h A N W ells s eattle Discovery Institute Press 2011 Description According to a number of leading proponents of Darwin’s theory, “junk DNA”—the non-protein coding portion of DNA—provides decisive evidence for Darwinian evolution and against intelligent design, since an intelligent designer would presumably not have filled our genome with so much garbage. But in this provocative book, biologist Jonathan Wells exposes the claim that most of the genome is little more than junk as an anti-scientific myth that ignores the evidence, impedes research, and is based more on theological speculation than good science. Copyright Notice Copyright © 2011 by Jonathan Wells. All Rights Reserved. Publisher’s Note This book is part of a series published by the Center for Science & Culture at Discovery Institute in Seattle. Previous books include The Deniable Darwin by David Berlinski, In the Beginning and Other Essays on Intelligent Design by Granville Sewell, God and Evolution: Protestants, Catholics, and Jews Explore Darwin’s Challenge to Faith, edited by Jay Richards, and Darwin’s Conservatives: The Misguided Questby John G. West. Library Cataloging Data The Myth of Junk DNA by Jonathan Wells (1942– ) Illustrations by Ray Braun 174 pages, 6 x 9 x 0.4 inches & 0.6 lb, 229 x 152 x 10 mm. & 0.26 kg Library of Congress Control Number: 2011925471 BISAC: SCI029000 SCIENCE / Life Sciences / Genetics & Genomics BISAC: SCI027000 SCIENCE / Life Sciences / Evolution ISBN-13: 978-1-9365990-0-4 (paperback) Publisher Information Discovery Institute Press, 208 Columbia Street, Seattle, WA 98104 Internet: http://www.discoveryinstitutepress.com/ Published in the United States of America on acid-free paper.
    [Show full text]
  • Snapshot: Network Motifs Oren Shoval and Uri Alon Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel
    SnapShot: Network Motifs Oren Shoval and Uri Alon Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel 326 Cell 143, October 15, 2010 ©2010 Elsevier Inc. DOI 10.1016/j.cell.2010.09.050 See online version for legend and references. SnapShot: Network Motifs Oren Shoval and Uri Alon Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel Transcription regulation and signaling networks are composed of recurring patterns called network motifs. Network motifs are much more prevalent in biological networks than would be expected by comparison to random networks and comprise almost the entire network structure. The same small set of network motifs has been found in diverse organ- isms ranging from bacteria to plants to humans. Experiments show that each network motif can carry out specific dynamic functions in the computation done by the cell. Here we review the main classes of network motifs and their biological functions. Autoregulation Negative autoregulation (NAR) occurs when a transcription factor represses the transcription of its own gene. (We use transcription to help make examples concrete; all circuits described here could operate also in other regulatory modes, e.g., a protein inhibiting its own activity by autophosphorylation.) This occurs in about half of the repressors in E. coli and can speed up the response time of gene circuits and reduce cell–cell variation in protein levels that are due to fluctuations in production rate. Positive autoregulation occurs when a transcription factor enhances its own rate of production. Response times are slowed and variation is usually enhanced. This motif, given sufficient cooperativity, can lead to bimodal (all-or-none) distributions, where the concentration of X is low in some cells but high in others.
    [Show full text]