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Clinical-Protocol-Guideline.Pdf
MINISTRY OF AYUSH Government of India Interdisciplinary AYUSH Research & Development Task Force Guidelines for AYUSH Clinical Studies in COVID-19 2nd APRIL to 2nd MAY 2020 Table of Contents 1. Clinical Trials on AYUSH Interventions for COVID-19: Methodology and Protocol Development 2. Annexure One - Protocol outline for Population based AYUSH studies for Prophylaxis against COVID-19 3. Annexure Two - Outline for developing CRFs for Population based AYUSH studies for COVID-19 4. Annexure Three - Protocol outline for AYUSH interventional studies for COVID-19 5. Annexure Four - Illustrative Protocol for Stand Alone Intervention AYUSH studies for COVID-19 6. Annexure Five - Protocol Outline for Integrative Clinical Trials for COVID-19 7. Task Force and Working Groups Guidelines for Clinical Trials on AYUSH interventions for COVID-19 – by ID-AYUSH-R&D Task Force - 2020 Clinical Trials on AYUSH Interventions for COVID-19: Methodology and Protocol Development A Publication by Interdisciplinary AYUSH Research and Development Task Force Ministry of AYUSH, Govt. of India April 2020 1 Guidelines for Clinical Trials on AYUSH interventions for COVID-19 – by ID-AYUSH-R&D Task Force - 2020 Contents AYUSH Initiatives for COVID Research .............................................................................. 3 Clinical Trial Protocol – Development and Implementation .................................................. 3 Protocol development ........................................................................................................ 4 National -
Effect of Rasayana Therapy on Ageing: an Ayurvedic Perspective1
Effect of Rasayana Therapy on Ageing: An Ayurvedic Perspective1 R.D.H Kulatunga * Abstract Ageing is a multidimensional process of physical, psychological and social change. Ayurveda Rasayana2 therapy has given powerful contribution to overcome age related disorders and act essentially on nutrition dynamics and rejuvenate the body and the mind. The present study has been carried out to assess the effect of Guduchyadi Rasayana3 on Agnibala4, Dehabala5 and Sattvabala6 on elderly individuals. 138 patients were registered to the study and divided in to two groups. The drugs were prepared as granules form and administered three times per day and continued for three months. Result of the study revealed that the trial group obtained statistically sig- nificant improvement in the signs and symptoms of Agnibala, Dehabala and Sattvabala on elderly individuals. Keywords: Ageing; Guduchyadi Rasayana; Rasayana Therapy 1. This paper is based on the PhD research work carried out at Institute for Post Graduate Teaching and Research in Ayurveda at Gujarat Ayurved University, Jamnagar, India, 2011. * Senior Lecturer, Department of Kayachikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka. e-mail: [email protected] 2. Rejuvenation 3. Name of the trial drug 4. Power of digestion and metabolism 5. Strength of body 6. Strength of the mind 102 Sri Lanka Journal of Advanced Social Studies Vol. 3 - No. 1-January- June -2013 Introduction Ageing is essentially a physiological phenomenon usually defined as the progressive loses of biological functions accompanied by decreasing fertility and increasing mortality with advancing age. It represents structural and functional changes of an organism over its life span. -
Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed Cases of Mucormycosis
Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed cases of Mucormycosis Government of India Ministry of Ayush Drug Policy Section Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed cases of Mucormycosis Preamble India has been battling with a significant rise in COVID-19 cases in the second wave. A severe and rare fungal illness, Mucormycosis also known as “black fungus”, affecting some coronavirus patients is causing a double blow to the country. Mucormycosis infections are more severe in people with comorbid conditions like Diabetes, Hypertension etc. and immune- compromised state. Because of the increase in the number of patients with this deadly infection, many states have declared Mucormycosis as an epidemic and has become a matter of huge concern. Mucormycosis is classified mainly into five types depending on the part of the body affected. The clinical features described of Rhino-orbito-cerebral Mucor mycosis are similar to Raktaja Pratishyaya and Krimija Shiroroga (unilateral facial swelling, Headaches, Nasal congestion, Nasal discharge, Fever etc). Presentation of Pulmonary Mucor mycosis are very much similar to Kshayaja Kasa, (Cough with pericardial chest pain, foul smelling, greenish, purulent, mucoid and blood stained/ haemoptysis sputum and cough associated with fever (Jvaro-mishrakriti) or chest pain (Parshvaruka) or recurrent coryza (Pinasa) are the clinical features found in Pulmonary Mucourmycosis. The Gastrointestinal Mucormycosis can be included under the spectrum of Udara roga especially Sannipatika udara roga and pathogenesis of Disseminated mucormycosis in later phase can be compared with Dushtavrana where as Cutaneous mucormycosis can be correlated with Kushtha and Visarpa. -
Review Article
S. Vasan Satish et al/ Int. J. Res. Ayurveda Pharm. 8 (6), 2017 Review Article www.ijrap.net ROLE OF PATHYA AHARA IN SHODHANA WITH REFERENCE TO SAMSARJANA KRAMA: A REVIEW S. Vasan Satish 1*, M.R. Kavyashree 2, M. Ashvinikumar 3, B.A Lohith 4, Rajan Amritha 5 1PG Scholar, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 2PG Scholar, Department of Dravyaguna, SDM College of Ayurveda, Hassan, Karnataka, India 3Professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 4Head, and Associate Professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 5Assistant professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India Received on: 07/09/17 Accepted on: 17/10/17 *Corresponding author E-mail: [email protected] DOI: 10.7897/2277-4343.086291 ABSTRACT Importance of Ayurveda in global scenario is because of its holistic approach towards positive life style. Ayurveda is continuously getting developed as a result of various ongoing discussion and research. Ayurveda is a science which gives importance to diet and regimen supplementing the chikitsa. Pathyaahara has a major supportive role in management of diseases. Shodhana is the supreme therapy as the disease cured by shodhana is not likely to reoccur. Vamana (emesis), Virechana (purgation), Niruhabasti (decoction enema) Nasya (errhine), Rakthamokshana (blood letting) are the five shodhana therapies carried out systematically in three stages which are pre therapy, therapy and post therapy. Post therapies vary according to the shodhana karma. It is mainly focused on strict-sequential-graduated dietary regimen called samsarjanakrama, to regain the hampered agni after vamana and virechana. -
A Critical Analysis of Samsarjana Krama
wjpmr, 2018,4(3), 176-183 SJIF Impact Factor: 4.639 WORLD JOURNAL OF PHARMACEUTICAL Review Article Megha . World Journal of Pharmaceutical and Medical ResearchISSN 2455 -3301 AND MEDICAL RESEARCH www.wjpmr.com WJPMR A CRITICAL ANALYSIS OF SAMSARJANA KRAMA Dr. Megha R. Survase* Assistant Professor, Department of Panchakrama, CSMSS Ayurveda Mahavidyalaya, Aurangabad. *Corresponding Author: Dr. Megha R. Survase Assistant Professor, Department of Panchakarma, CSMSS Ayurveda Mahavidyalaya, Aurangabad. Article Received on 14/01/2018 Article Revised on 04/02/2018 Article Accepted on 25/02/2018 ABSTRACT Shodhana and Shaman are two treatment principles in Ayurveda. Panchakarma is Shodhana treatment which includes Vamana, Virechana, Vasti, Nasya, Raktamokshana. Every Panchakarma is done in three stages poorvakarma, pradhana krama, and paschat krama.All of these stages has been given its own importance and relevance. In paschat krama, there are some paschat karma done immediately after pradhana karma like kavala, gandush, dhoompana and some paschat karma done in sequential order to restore agni bala. This sequential order are been followed in samsarjana krama, tarpanadi krama, rasa avacharan krama as per given in classics. The different ways of giving samsarjana krama, tarpanadi krama and rasa avacharan krama, according to classics are critically analyzed in this paper Its modified way of giving is also been discussed in this paper. This paper also focuses on the practical problems faced by physician in case of vegetarians and highlights on the substitute which can be given instead. KEYWORDS: Samsarjana krama, Tarpanadi krama, Ras avacharana krama, Paschat karma. INTRODUCTION reason for samsarjana krama in case of vamana and virechana is explained in Chakrapani that there is Ayurvedic management of diseases is generally, prabhrut elimination of doshas which causes kshobha in classified into "Shodhana” and “Shamana” treatments.[1] the body leading to agnimandya and for agni Out of which the Shodhana therapy, has been given sandhukshan samsarjana krama is followed. -
International Journal of Ayurveda and Pharma Research
ISSN: 2322 - 0902 (P) ISSN: 2322 - 0910 (O) International Journal of Ayurveda and Pharma Research Review Article COMPREHENSIVE ACCOUNT OF SARPAVISHA WITH SPECIAL REFERENCE TO BRIHATTRAYI Samata Tomar1, Pravin Jawanjal2* 1HOD, Dept. of Agadatantra, Shree Gulabkunverba Ayurved Mahavidyalaya, Jamnagar, Gujarat, India. *2PhD Scholar, Dept. of Ras shastra, IPGT&RA, Jamnagar, Gujarat, India. ABSTRACT Agadatantra (Ayurvedic toxicology) being the sixth branch of Ashtaanga Ayurveda deals with the study of Jaangam (animate) and (Sthavara) inanimate poisons, their symptoms and management. Here is an attempt to collect all references regarding Sarpa Visha described in Brihattrayi. As theory and practice are the two wings of knowledge, literature review is the foundation of applied sciences. Ancient man is forests dweller. There is a dire need of protection from plant and animal poisoning, hence branch of Agadatantra (toxicology) is well established at that time. Material and methods: Brihattrayi (Major classics) of Ayurveda had been referred for literature review. Past studies and researches regarding the topic also been probed. Objectives: To present a comprehensive account of snake management in Ayurveda. Discussion: Data is presented under the headings of snake identification, specific signs and symptoms and Vega (stage) wise treatment with Agadas and role of Agadatantra in snakebite management as a first aid. Conclusion: Systematically presented data will prove a ready reckoner for UG, PG Scholars and researchers, zoologists for easy referencing. Snake bite management through different antidotes mentioned as Agadas in classical texts. These formulations need to be researched with modern parameters of Invivo and Invitro studies. KEYWORDS: Ayurveda, Agadas, Sarpavisha, Classification, Management. INTRODUCTION Major texts i.e. -
Urine Stem Cell Therapy
2/1/2014 Outlook - [email protected] *********************************************************************************************************** 1.) article in - The Independant - newspaper ************************** http://www.independent.co.uk/life-style/health-and-families/health-news/urine-the-bodys-own-health-drink-467303.htm *********************************************************************** 2 .) Urine stem cell Therapy People have lived for days without food or water. They survived because they drank their own urine, those that didn't died. In the past, Doctors were trained in the analysis of urine by looking at it, smelling it and tasting a patients urine. Astronauts drink their purified urine in space for months without any adverse effects. Urine is a by-product of blood filtration, not waste filtration, and is non-toxic. The body secretes elements not needed at the time through urine. Urine contains compounds that are very specific to the individual from which it comes. It is antibacterial, antifungal, antiviral, antineoplastic (anticancer) , anticonvulsive, and antispasmodic. Urine is a sterile body compound that is purer than distilled water (no bacteria). Urine contains thousands of compounds and packed with stem cells. Urine contains: Alanine, Arginine, Ascorbic acid, Allantoin, Amino acids, Bicarbonate, Biotin, Calcium, Creatinine, Cystine, DHEA, Dopamine, Epinephrine, Folic acid, Glucose, Glutamic acid, Glycine, Inositol, Iodine, Iron, Lysine, Magnesium, Manganese, Melatonin, Methionine, Nitrogen, Ornithane, -
Textbook of Ayurveda: Volume 3
Textbook of Ayurveda General Principles of Management and Treatment Vo l u m e T h r e e by Vasant D. Lad, M.A.Sc. Albuquerque, New Mexico Table of Contents Foreword ~ / xv About the Author ~ / xix The Use of Sanskrit ~ / xxi 1 Chikits¡ ~ ¢yurvedic Management and Treatment of Disease to Bring a State of Balance / 1 ¢yurveda Treatment Protocols / 4 Complications, Multiple Pathologies, and Drug-Related Disorders / 13 The Four Pillars of Chikits¡ / 15 Agni and K¡ya Chikits¡ / 17 The Main Categories of Chikits¡ / 19 Detailed Categories of Chikits¡ / 21 A. Internal Shodhana / 21 B. External Shodhana / 23 C. Internal Shamana / 24 D. External Shamana / 24 Santarpana and Apatarpana Chikits¡ / 25 Examples of Santarpana (Anabolic) Therapy / 26 Examples of Apatarpana (Catabolic) Therapy / 26 Apunarbhava Chikits¡ / 27 Trividh¡ Chikits¡ / 28 Vih¡ra or ¢ch¡ra Chikits¡, Lifestyle or Behavioral Medicine / 28 Summary / 30 2 Dosha Gati ~ How a Dosha Moves During the Disease Process / 33 Downward, Upward, and Linear Gatis / 34 Adho V¡ta / 34 ¿rdhva V¡ta / 35 Tiryag V¡ta / 36 Adho Pitta / 36 ¿rdhva Pitta / 37 Tiryag Pitta / 38 Adho Kapha / 38 ¿rdhva Kapha / 39 Tiryag Kapha / 39 Multiple Gatis / 39 Blood Disorders with Adho, ¿rdhva, and Tiryag Gati / 40 Serious Dosha Disorders with Adha, ¿rdhva, and Tiryag Gati / 43 Increased, Decreased, and Stable Gatis / 45 Increased Dosha (Vruddhi) / 45 vii Decreased Dosha (Kshaya) / 46 Stable Dosha (Sth¡na) / 46 Koshtha, Sh¡kh¡, and Marma Gatis / 47 Koshtha Gati / 47 Sh¡kh¡ Gati / 47 Marma Gati / 50 Summary / 51 3 Vega -
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ISSN: 2322 - 0902 (P) ISSN: 2322 - 0910 (O) International Journal of Ayurveda and Pharma Research Review Article A CRITICAL REVIEW ON ACTION OF SWEDANA VIS-À-VIS SUDATION THERAPY Akhilanath Parida1*, Satyasmita Jena2, Varun Sawant3 *1Professor, Department of Panchakarma, V.Y.D.S Ayurveda College, Khurja, India 2Assistance Professor, Department of Prasuti Tantra Stree Roga, V.Y.D.S Ayurveda College, Khurja, India 3Assistance Professor, Department of Samhita and Siddhanta, V.Y.D.S Ayurveda College, Khurja, India. ABSTRACT Swedanam is a therapy which alleviates stiffness, heaviness, coldness & that which brings out sweating from the system is sudation therapy. The perspiration brought about by the sudation therapy is more than the normal. Conventionally the sudation therapy is just understood as the steam bath, but sudation in Ayurveda is something more as a treatment & as a daily routine. Swedana drugs by Ushna and Tikshnaguna are capable of penetrating the microcirculatory channels (Srotas) where they activate the sweat glands to produce mores heat. Swedana Karma hastens this process by increasing the permeability of capillary and bringing the morbidities into an extracellular fluid by dilating and clearing the channels of the body. Swedanakarma maintains the thermoregulation system of the body by maintaining quilibrium between core temperature (temp. inside the body) and shell temperature (skin temp). KEYWORDS: Swedana karma, Sudation therapy, Sweating. INTRODUCTION Sweating treatment (Swedana) is usually Swedana Guna (properties) and its action of body given after oleation- Snehana therapy. Swedana is the [5] procedure that relieves Stambha, Gaurava, Sheeta Ushnata: This is originated from Agneyaguna and is which induces Swedana (Sweating).[1] It plays a dual opposite to Shitaguna. -
AN AYURVEDIC OUTLOOK on VISHAD (DEPRESSION) and ITS MANAGEMENT Name of Author: - Dr
www.ijcrt.org © 2021 IJCRT | Volume 9, Issue 5 May 2021 | ISSN: 2320-2882 AN AYURVEDIC OUTLOOK ON VISHAD (DEPRESSION) AND ITS MANAGEMENT Name of Author: - Dr. Sanjay A. Dhurve (M.D., Ph.D.) Assistant Professor, Department of Kayachikitsa, Bharati Vidyapeeth Deemed University College of Ayurved, Pune -Satara Road, Pune-411043. ABSTRACT: - Depressive disorders commonly affect wide population due to causative factors such as irregular food habits, peer pressures and mental stress. Traditional Ayurvedic literature reveals that the premonitory symptoms of Unmada and Vishad term used in ayurvedic classics can be co-related with symptoms of depression denoting restricted or hypokinetic activities of speech, body and mind. In management of depressive disorders various herbal and herbo-mineral formulations are prescribed in Ayurvedic system. KEY WORDS: - Vishad, depression, Unmada, Chikitsa INTRODUCTION: - Depression is a mood disorder characterized by loss of interest, feelings of guilt, reduced desire of sex etc. Depressive disorders commonly affect wide population due to causative factors such as irregular food habits, peer pressures and mental stress. It is currently believed that depression is primarily the result of biochemical alterations in the brain. Recurrent episodes of this disorder lead into chronic state of disease. Traditional ayurvedic literature reveals that changes in dietary and lifestyle habits leads to disturb physiological as well mental attributes. Imbalance in the equilibrium of the mental and physical attributes, results in depletion of Dhriti (retaining power of mind), Smriti (hampered memory), Bhuddhi (hampered intellect) Thus, predisposing to occur any of psycho-somatic disorders as well mental illness such as Unmada [Insanity], Apasmar (Epilepsy). The pre- monitory symptoms of Unmada can be co-related with symptoms of depression as both are seen to be similar i.e., emptiness in thought, dysfunction of intellect and impairment of memory. -
On the Technique of Sodhana
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by PubMed Central Ancient Science of life Vol No XVI I July 1996, Page 67-73 ON THE TECHNIQUE OF SODHANA ANJANA CHAUBE, P.K PRAJAPATI and S.K DIXIT Department of Rasashastra, I.M.S., B.H.U., Varanasi – 221 005 Received: 6 February 1996 Accepted: 23 April,1996 ABSTRACT: Sodhana is a particular aspect to be followed meticulously in ayurvedic pharmaceutics. Failure to subject certain ingredients to this process of “purification” can have a negative effect on the efficacy of the preparations(s). This aspect is detail in this article. INTRODUCTION were the pioneer to use the metals for medicinal purposes as prehistoric texts like Ayurveda –the science of life is known to “Rigveda” and Atharvaveda: have the mankind since time immemorial. It mentioned the medicinal values of the noble prolongs life span, maintains positive health metals like gold and silver. and cures diseases. With a view to achieve these aims and objectives different types of After the development of rasa Shastra it was drugs, found in nature from the natural made possible for the minerals and metals, resources whether these may be herbal precious and semiprecious stones to pass animal or minerals have been in use. The through various pharmaceutical processes drugs of herbal origin come first in the series like shodhana, Jarana Marana etc for several because of their easy availability and easy times so as to convert these in to a form or processing but after sometime, in addition to compound which may suit to the human the herbal drugs, mani (previous stones or body and could be observed and assimilated gems) mantra (hymns), shastra (surgical easily into the system without exhibiting any instruments), agni (fire) and kshara (Alkali) toxic symptom. -
The Effect of Virechana with Manibhadra Churna in Psoriasis – a Case Study by Maneesha
Global Journal of Medical Research: B Pharma, Drug Discovery, Toxicology & Medicine Volume 21 Issue 1 Version 1.0 Year 2021 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Online ISSN: 2249-4618 & Print ISSN: 0975-5888 The Effect of Virechana with Manibhadra Churna in Psoriasis – A Case Study By Maneesha. P.C & Shaiju Krishnan PG Scholar Abstract- Panchakarma is referred as penta-biopurificatory process. Virechana Karma is one among Panchakarma; by which orally administered drug acts on internal Dosha especially Pitta Dosha and expel them out of the body through Guda. Psoriasis is a common chronic skin disorder of autoimmune origin. A 42 year old male patient c/o itching overhead, behind the ears, nails, lower back and legs since 2 years and while itching he gets whitish powder. He has consulted a dermatologist and has taken modern medicine. He got symptomatic relief. As soon as he stops medicines, the condition worsens and reoccurrence of disease was going on. Meanwhile severe burning sensation on chest was also happened. So he has planned to take Ayurveda treatment for the same. There was no history of any systemic illness. The present case was diagnosed as psoriasis from a detailed history taking and clinical examination. A positive family history was noted. A classical way of Virechana Karma was planned with Manibhadra Churna. After Virechana, Samyaka Shudhi Lakshana was achieved; symptoms such as itching, erythema, scaling, candle grease sign and Auspitz sign were not found. Reoccurrence of disease was not found even after 2nd follow up. Keywords: virechana, psoriasis, manibhadra churna, kushta.