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Clinical-Protocol-Guideline.Pdf
MINISTRY OF AYUSH Government of India Interdisciplinary AYUSH Research & Development Task Force Guidelines for AYUSH Clinical Studies in COVID-19 2nd APRIL to 2nd MAY 2020 Table of Contents 1. Clinical Trials on AYUSH Interventions for COVID-19: Methodology and Protocol Development 2. Annexure One - Protocol outline for Population based AYUSH studies for Prophylaxis against COVID-19 3. Annexure Two - Outline for developing CRFs for Population based AYUSH studies for COVID-19 4. Annexure Three - Protocol outline for AYUSH interventional studies for COVID-19 5. Annexure Four - Illustrative Protocol for Stand Alone Intervention AYUSH studies for COVID-19 6. Annexure Five - Protocol Outline for Integrative Clinical Trials for COVID-19 7. Task Force and Working Groups Guidelines for Clinical Trials on AYUSH interventions for COVID-19 – by ID-AYUSH-R&D Task Force - 2020 Clinical Trials on AYUSH Interventions for COVID-19: Methodology and Protocol Development A Publication by Interdisciplinary AYUSH Research and Development Task Force Ministry of AYUSH, Govt. of India April 2020 1 Guidelines for Clinical Trials on AYUSH interventions for COVID-19 – by ID-AYUSH-R&D Task Force - 2020 Contents AYUSH Initiatives for COVID Research .............................................................................. 3 Clinical Trial Protocol – Development and Implementation .................................................. 3 Protocol development ........................................................................................................ 4 National -
Effect of Rasayana Therapy on Ageing: an Ayurvedic Perspective1
Effect of Rasayana Therapy on Ageing: An Ayurvedic Perspective1 R.D.H Kulatunga * Abstract Ageing is a multidimensional process of physical, psychological and social change. Ayurveda Rasayana2 therapy has given powerful contribution to overcome age related disorders and act essentially on nutrition dynamics and rejuvenate the body and the mind. The present study has been carried out to assess the effect of Guduchyadi Rasayana3 on Agnibala4, Dehabala5 and Sattvabala6 on elderly individuals. 138 patients were registered to the study and divided in to two groups. The drugs were prepared as granules form and administered three times per day and continued for three months. Result of the study revealed that the trial group obtained statistically sig- nificant improvement in the signs and symptoms of Agnibala, Dehabala and Sattvabala on elderly individuals. Keywords: Ageing; Guduchyadi Rasayana; Rasayana Therapy 1. This paper is based on the PhD research work carried out at Institute for Post Graduate Teaching and Research in Ayurveda at Gujarat Ayurved University, Jamnagar, India, 2011. * Senior Lecturer, Department of Kayachikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka. e-mail: [email protected] 2. Rejuvenation 3. Name of the trial drug 4. Power of digestion and metabolism 5. Strength of body 6. Strength of the mind 102 Sri Lanka Journal of Advanced Social Studies Vol. 3 - No. 1-January- June -2013 Introduction Ageing is essentially a physiological phenomenon usually defined as the progressive loses of biological functions accompanied by decreasing fertility and increasing mortality with advancing age. It represents structural and functional changes of an organism over its life span. -
Effect of Rasayana Chikitsa in Micro Vascular Complications of Madhumeha”
wjpmr, 2020,6(11), 222-226 SJIF Impact Factor: 5.922 Review Article WORLD JOURNAL OF PHARMACEUTICAL Verma et al. AND MEDICAL RESEARCHWorld Journal of Pharmaceutical and Medical ResearchISSN 2455 -3301 www.wjpmr.com Wjpmr A REVIEW STUDY ON “EFFECT OF RASAYANA CHIKITSA IN MICRO VASCULAR COMPLICATIONS OF MADHUMEHA” Dr. Kalpana Verma*1 and Dr. Ashish Pareek2 1Assistant Professor Department of Shalya Tantra, Institute of AYUSH Medical Science Lucknow. 2Assistant Professor Department of Shalya Tantra, S.S.S.B. Ayurveda College & Hospital, Renwal, Jaipur. *Corresponding Author: Dr. Kalpana Verma Assistant Professor Department of Shalya Tantra, Institute of AYUSH Medical Science Lucknow. Article Received on 17/09/2020 Article Revised on 07/10/2020 Article Accepted on 28/10/2020 ABSTRACT Background & objective: Diabetes Mellitus is one of the major metabolic disorders, characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Diabetes associated with long term potential effect on almost all systems of body. It leads to various complications. These complications can be managed by Rasayana Chikitsa (Rejuvenation therapy) according to Ayurveda which nourishes, develops & corrects the vitiated Saptadhatu. Objective: To study the Micro vascular complications in Madhumeha. To study Rasayana dravya from samhitas. To evaluate the Karmukatva (Activity) of Rasayana dravya on Micro vascular complications. Material and Methodology: Literary study of Rakta-Medodushti in complications of Madhumeha thoroughly was done. Literary study of micro vascular complication of Diabetes was done, Karmukatva of Rasayana dravya on micro vascular complications was studied. Result: Diabetic Neuropathy, Nephropathy & Retinopathy are the micro vascular complications of Madhumeha. These complications are mainly due to Rakta- Medo dushti. -
Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed Cases of Mucormycosis
Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed cases of Mucormycosis Government of India Ministry of Ayush Drug Policy Section Information for Ayurveda Practitioners for Prophylactic, Symptomatic Management of Suspected and Diagnosed cases of Mucormycosis Preamble India has been battling with a significant rise in COVID-19 cases in the second wave. A severe and rare fungal illness, Mucormycosis also known as “black fungus”, affecting some coronavirus patients is causing a double blow to the country. Mucormycosis infections are more severe in people with comorbid conditions like Diabetes, Hypertension etc. and immune- compromised state. Because of the increase in the number of patients with this deadly infection, many states have declared Mucormycosis as an epidemic and has become a matter of huge concern. Mucormycosis is classified mainly into five types depending on the part of the body affected. The clinical features described of Rhino-orbito-cerebral Mucor mycosis are similar to Raktaja Pratishyaya and Krimija Shiroroga (unilateral facial swelling, Headaches, Nasal congestion, Nasal discharge, Fever etc). Presentation of Pulmonary Mucor mycosis are very much similar to Kshayaja Kasa, (Cough with pericardial chest pain, foul smelling, greenish, purulent, mucoid and blood stained/ haemoptysis sputum and cough associated with fever (Jvaro-mishrakriti) or chest pain (Parshvaruka) or recurrent coryza (Pinasa) are the clinical features found in Pulmonary Mucourmycosis. The Gastrointestinal Mucormycosis can be included under the spectrum of Udara roga especially Sannipatika udara roga and pathogenesis of Disseminated mucormycosis in later phase can be compared with Dushtavrana where as Cutaneous mucormycosis can be correlated with Kushtha and Visarpa. -
Review Article
S. Vasan Satish et al/ Int. J. Res. Ayurveda Pharm. 8 (6), 2017 Review Article www.ijrap.net ROLE OF PATHYA AHARA IN SHODHANA WITH REFERENCE TO SAMSARJANA KRAMA: A REVIEW S. Vasan Satish 1*, M.R. Kavyashree 2, M. Ashvinikumar 3, B.A Lohith 4, Rajan Amritha 5 1PG Scholar, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 2PG Scholar, Department of Dravyaguna, SDM College of Ayurveda, Hassan, Karnataka, India 3Professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 4Head, and Associate Professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India 5Assistant professor, Department of Panchakarma, SDM College of Ayurveda, Hassan, Karnataka, India Received on: 07/09/17 Accepted on: 17/10/17 *Corresponding author E-mail: [email protected] DOI: 10.7897/2277-4343.086291 ABSTRACT Importance of Ayurveda in global scenario is because of its holistic approach towards positive life style. Ayurveda is continuously getting developed as a result of various ongoing discussion and research. Ayurveda is a science which gives importance to diet and regimen supplementing the chikitsa. Pathyaahara has a major supportive role in management of diseases. Shodhana is the supreme therapy as the disease cured by shodhana is not likely to reoccur. Vamana (emesis), Virechana (purgation), Niruhabasti (decoction enema) Nasya (errhine), Rakthamokshana (blood letting) are the five shodhana therapies carried out systematically in three stages which are pre therapy, therapy and post therapy. Post therapies vary according to the shodhana karma. It is mainly focused on strict-sequential-graduated dietary regimen called samsarjanakrama, to regain the hampered agni after vamana and virechana. -
Urinary Tract Infection (UTI): Western and Ayurvedic Diagnosis and Treatment Approaches
Urinary tract infection (UTI): Western and Ayurvedic Diagnosis and Treatment Approaches. By: Mahsa Ranjbarian Urinary system Renal or Urinary system is one of the 10 body systems that we have. This system is the body drainage system. The urinary system is composed of kidneys (vrikka), ureters (mutravaha nadis), bladder(mutrashaya) and urethra(mutramarga). The kidneys are a pair of bean-shaped, fist size organs that lie in the middle of the back, just below the rib cage, one on each side of the spine. Ureters are tubes that carry the wastes or urine from the kidneys to the bladder. The urine finally exit the body from the urethra when the bladder is full.1 Urethras length is shorter in women than men due to the anatomical differences. Major function of the urinary system is to remove wastes and water from our body through urination. Other important functions of the urinary system are as follows. 1. Prevent dehydration and at the same time prevent the buildup of extra fluid in the body 2. Cleans the blood of metabolic wastes 3. Removing toxins from the body 4. Maintaining the homeostasis of many factors including blood PH and blood pressure 5. Producing erythrocytes 6. make hormones that help regulate blood pressure 7. keep bones strong 8. keep levels of electrolytes, such as potassium and phosphate, stable 2 The Urinary system like any other systems of our body is working under the forces of three doshas, subdoshas. Mutravaha srotas, Ambuvahasrota and raktavahasrota are involved in formation and elimination of the urine. Urine gets separated from the rasa by maladhara kala with the help of pachaka pitta and samana vayu and then through the mutravaha srota(channels carrying the urine) it is taken to the bladder. -
Critical Appraisal of the Concept of Shodhana and Sadyashodhana Among the Panchakarma
Int J Ayu Pharm Chem REVIEW ARTICLE www.ijapc.com e-ISSN 2350-0204 Critical Appraisal of the Concept of Shodhana and Sadyashodhana among the Panchakarma 1 2 Satyajit P. Kulkarni *, Milind M. Godbole and Sanjay S. Jadhav3 1Swasthavritta, Yashwant Ayurvedic College and P.G.T.R.C. Kodoli, Kolhapur, Maharashtra, India 2,3 Panchakarma, Yashwant Ayurvedic College and P.G.T.R.C. Kodoli, Kolhapur, Maharashtra, India Abstract Shodhana or Panchakarma is the very important part of the Ayurvedic treatment. The period during which Charak Samhita was written, it would have been practiced in greater proportion. There is detailed description about Panchakarma or Shodhana in Charak Samhita, Sushrut Samhita and Ashtang Sangrah (and Ashtang Hridayam). These texts are called as Brihat Trayi . Sharangdhar Samhita and Bhavprakash described Panchakarma concisely as compared to the Brihat Trayi texts. Every disease is told to be treated with Shodhana first1 and Shamana thereafter. The Kalpa sthana and Sidhi sthana of Charak Samhita are solely dedicated to the Shodhana. Thus being an important treatment modality Shodhana is very useful in achieving both the goals of Ayurveda i.e., for maintaining health in the healthy and to treat the disease in the diseased one. This paper deals with theory part of the Shodhana to be applied in the healthy and the diseased. The paper also highlights the difference in implementing the Shodhana in the diseased and healthy one. Keywords Shodhana, Sadyashodhana, Panchakarma Greentree Group Received 06/10/15 Accepted 16/12/15 Published 10/01/16 ________________________________________________________________________________________________________ Satyajit et al. 2016 Greentree Group © IJAPC Int J Ayu Pharm Chem 2015 Vol. -
A Critical Analysis of Samsarjana Krama
wjpmr, 2018,4(3), 176-183 SJIF Impact Factor: 4.639 WORLD JOURNAL OF PHARMACEUTICAL Review Article Megha . World Journal of Pharmaceutical and Medical ResearchISSN 2455 -3301 AND MEDICAL RESEARCH www.wjpmr.com WJPMR A CRITICAL ANALYSIS OF SAMSARJANA KRAMA Dr. Megha R. Survase* Assistant Professor, Department of Panchakrama, CSMSS Ayurveda Mahavidyalaya, Aurangabad. *Corresponding Author: Dr. Megha R. Survase Assistant Professor, Department of Panchakarma, CSMSS Ayurveda Mahavidyalaya, Aurangabad. Article Received on 14/01/2018 Article Revised on 04/02/2018 Article Accepted on 25/02/2018 ABSTRACT Shodhana and Shaman are two treatment principles in Ayurveda. Panchakarma is Shodhana treatment which includes Vamana, Virechana, Vasti, Nasya, Raktamokshana. Every Panchakarma is done in three stages poorvakarma, pradhana krama, and paschat krama.All of these stages has been given its own importance and relevance. In paschat krama, there are some paschat karma done immediately after pradhana karma like kavala, gandush, dhoompana and some paschat karma done in sequential order to restore agni bala. This sequential order are been followed in samsarjana krama, tarpanadi krama, rasa avacharan krama as per given in classics. The different ways of giving samsarjana krama, tarpanadi krama and rasa avacharan krama, according to classics are critically analyzed in this paper Its modified way of giving is also been discussed in this paper. This paper also focuses on the practical problems faced by physician in case of vegetarians and highlights on the substitute which can be given instead. KEYWORDS: Samsarjana krama, Tarpanadi krama, Ras avacharana krama, Paschat karma. INTRODUCTION reason for samsarjana krama in case of vamana and virechana is explained in Chakrapani that there is Ayurvedic management of diseases is generally, prabhrut elimination of doshas which causes kshobha in classified into "Shodhana” and “Shamana” treatments.[1] the body leading to agnimandya and for agni Out of which the Shodhana therapy, has been given sandhukshan samsarjana krama is followed. -
Exploring the Concept of Leena(Concealed) Dosha and Application of Shodhana(Bio-Purification Therapy) in Amavata with Special Reference to Rheumatoid Arthritis
Original Research Paper Volume-9 | Issue-3 | March-2019 | PRINT ISSN - 2249-555X Ayurveda EXPLORING THE CONCEPT OF LEENA(CONCEALED) DOSHA AND APPLICATION OF SHODHANA(BIO-PURIFICATION THERAPY) IN AMAVATA WITH SPECIAL REFERENCE TO RHEUMATOID ARTHRITIS Reader, PG Dept of RogaNidana, Parul Institute of Ayurved, Vadodara, GUJARAT, Dr. Sachin. Deva 391760 Assistant Professor/Consultant, Dept of Panchakarma, Parul Institute of Ayurved & Dr. Divya. B Research, Khemdas Patel Ayurved Hospital, Vadodara, GUJARAT, 391760, ABSTRACT Roga(Disease) are Aparisankheyaya(Innumerable) with multiple cause and symptoms. History taking, physical examination and also laboratory investigations plays a key role in diagnosis of disease. Life encompasses the states of health and disease. Ayurveda, the spearhead science deals with these states of life. Various fervent concepts with sturdy bedrocks are laid down for understanding the body. Diagnosis and understanding of diseases is of prime relevance in the eld of medicine. Different principles and methods in unveiling the mechanism of disease have been mentioned in classical texts. One of the most alluring concepts is Leenadosha(Concealed) in the modulation of a disease. Technically Leena term suggests to Conceal/Attach or even Merge. Here the Doshas will be attached or concealed to the Dhatus. So we can frame the quality of Leena dosha as Ekadeshasthita/Anutva and also Dhatvantaragata(Concealed to dhatus). Ama(Toxins from undigested food) is considered as the basic cause for all the disease. The person who is liable to Mandagni(Decreased digestive re) undergoes Viruddahara then Amotpatti is certain. Sanchara(Movement) of Ama due to multiple etiology causes Sthanasamshraya(Connement) especially in Asti(Bones) and Sandhis(Joints) causes Shoola(Pain) in same areas. -
Traditional Medicine-Based Therapies for Cancer Management
Sys Rev Pharm. 2019;10(1):90-92. Review article A multifaceted Review journal in the field of Pharmacy Traditional medicine-based therapies for cancer management Pathirage Kamal Perera* Institute of Indigenous Medicine, University of Colombo, SRI LANKA. ABSTRACT In traditional Sri Lankan medicine, “Pilika” is the main term used to denote was made in this review to discuss about the etiopathogenesis of cancer cancer. But the terms “Gadu”, “Arbuda”, “Mas vana” are also other described in Ayurveda and traditional systems of medicine in Sri Lanka. names for cancer used in the literature. In Indian Ayurveda concepts, cancer is resemblance with entities of Arbuda and Granthi. Systems of Key words: Cancer, Ayurveda, Traditional Sri Lankan Medicine Traditional Medicine approaches are needed to further explore in cancer Correspondence: management to minimize the gap between modern understanding and Pathirage Kamal Perera traditional concepts. Hence a brief review on some of the important Institute of Indigenous Medicine, University of Colombo, SRI LANKA features used in Ayurveda and traditional Sri Lankan medicine was given Phone no: +94716419072 to understand the principles behind cancer management. Further attempt E-mail id: [email protected] DOI : 10.5530/srp.2019.1.15 INTRODUCTION Group II: Diseases that can be considered as cancer, such as incurable ulcers with e.g. tridosajgulmas (abdominal tumors like carcinomas of th Cancer is one of the most dreaded diseases of the 20 century and the stomach and liver or lymphomas). spreading further with continuance and increasing incidence in 21st century. Cancer in Sri Lanka is steadily on the rise. The country’s Group III: Diseases with the possibility of malignancy, e.g. -
Rheumatoid Arthritis) Through Multimodal Ayurveda Approach: a Case Study
International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Case Study Intervention of Amavata (Rheumatoid Arthritis) Through Multimodal Ayurveda Approach: A Case Study Dr Amrita Bhattarai1, Dr. Govind Kumawot2, Dr. Gopesh Mangal3 1MD Scholar, Department of Panchakarma, National Institute of Ayurveda, Jaipur, India. 2MD Scholar, Department of Panchakarma, National Institute of Ayurveda, Jaipur, India. 3Assistant Professor and Head, Department of Panchakarma, National Institute of Ayurveda, Jaipur, India. Corresponding Author: Dr Amrita Bhattarai ABSTRACT Amavata is second common joint disorder. Amavata is compared with Rheumatoid Arthritis based on similarities on signs and symptoms. Among various diseases that are managed through Ayurveda Amavata is one of them. RA is a chronic progressive disease causing inflammation in the joints and resulting in painful deformity and immobility, especially in the fingers, wrists, feet and ankles. The DMARDS and steroids used for management of Amavata have got various side effects and also don’t completely eradicate the disease. In this case study patient was given Vaitran Basti and Baluka Swedana along with some oral medicines i.e., Singhnad Guggulu 500mg twice daily, Rasna Saptak Kwath 40ml twice daily etc. So, Panchkarma procedures along with internal medications showed good result in the improvement of overall symptoms in this case of Amavata (Rheumatoid arthritis). Key words: Amavata, Rheumatoid arthritis, joint disorder, joint pain, Ayurveda approach. INTRODUCTION completely eradicate the disease. There are Rheumatoid Arthritis is a chronic various multimodal approaches followed in inflammatory disorder which affects the Ayurveda, practice for its management. The joints and is associated with swelling, disease is mainly due to derangement of stiffness and pain. -
3 | ISSUE- 9 SEPTEMBER 2020 Review of Untoward E
VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 VOLUME- 3 | ISSUE- 9 SEPTEMBER 2020 SJIF Impact Factor : 5.69 ISRA Impact Factor : 1.318 ISSN:2581-785X Review Article Volume: 3 Issue: 9 Review Of Untoward Effects Of Impure And Malprocessed Bhasma And Their Management Rachana Sharma1, Manisha Goyal2, Rajaram Agarwal3 1. P.G scholar, P.G Department of RasaShastra and BhaishajyaKalpana DSRRAU Jodhpur 2. Assistant Professor, P.G Department of RasaShastra and BhaishajyaKalpana DSRRAU Jodhpur 3. Associate Professor, P.G Department of RasaShastra and BhaishajyaKalpana DSRRAU Jodhpur ABSTRACT: Rasashastra plays an important role in Ayurveda. It’s a pharmaceutical branch of indian system of medicine. It deals mainly with various metals, minerals, mercury, animal products and other substances. In this text different types of shodhana and marana process are described for rasa, maharasa, uprasa, sadharana rasa, ratna, dhatu, upratnas etc. Bhasma is prepared by the marana process and it helps in easy absorption and assimilation due to micro fine element particles and does not produce any side effects in the human body, incinerated dravya will eradicate jara(old age), and diseases. Hence bhasma pareeksha like rekhapurana, apunarbhava, niruthaetc are also described in this text. Due to increase demand of rasaushadhis and commercialization, pharmaceutical companies are compromising with quality and standard of bhasma to prepare them in a short span of time, because processing of bhasma involves heavy labour and lot of tedious procedures like shodhana, mardana(bhawana), marana. If the shodhana process of metals and minerals is not done properly, then it acts as poison and reveals different types of complications in the human body like jwara, bhrama, vamana, kushtha, shool, mrityu etc.