Product Datasheet

GLIPR1 Antibody

Catalog No: #36505

Orders: [email protected] Description Support: [email protected]

Product Name GLIPR1 Antibody

Host Species Rabbit

Clonality Polyclonal

Purification Antigen affinity purification.

Applications WB IHC

Species Reactivity Hu Ms

Specificity The antibody detects endogenous levels of total GLIPR1 .

Immunogen Type Recombinant Protein

Immunogen Description Fusion protein corresponding to a region derived from internal residues of human GLI pathogenesis-related 1

Target Name GLIPR1

Other Names GLIPR; RTVP1; CRISP7

Accession No. Swiss-Prot#: P48060NCBI ID: 11010Gene Accssion: BC012510

SDS-PAGE MW 30kd

Concentration 2.6mg/ml

Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage Store at -20°C

Application Details

Western blotting: 1:500-1:2000

Immunohistochemistry: 1:100-1:300

Images

Gel: 10%SDS-PAGE Lysates (from left to right): Mouse kidney tissue Amount of lysate: 40ug per lane Primary antibody: 1/450 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Immunohistochemical analysis of paraffin-embedded Human liver tissue using #36505 at dilution 1/60.

Background

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on 12 containing two other similar . Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2