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Morris, Max From: Morris, Max Sent: Thursday, October 15, 2020 11:47 PM To: Morris, Max Subject: 10/15/2020 Coronavirus Daily Update These updates are being shared to multiple organizations, individuals and lists who/which are bcc’d. Best effort we are sending Daily updates during the business week, typically in the late afternoon or early evening, a Weekend Recap on Monday mornings, and any significant breaking news events provided anytime and on weekends. Please note some numbers included in the Statistics and news stories come from various sources and so can vary as they are constantly changing and not reported at the same time. All communications are TLP GREEN and can be shared freely. Know someone who might want to be added to our Updates? Of course ask them first, and then have them send us an email to [email protected]. Live the message, share the message: Be safe – Stay home and limit travel as much as possible, self-quarantine if you or any members of your family are or may be sick, if you go out wear your mask – the right way, ensure safe social distancing, and practice good hygiene – wash your hands, avoid touching your face, and sanitize used items and surfaces. Happy Thursday night Everyone! Well if I wait much longer we can say it’s Friday. Sorry for the late send but hope you All had a great day. The weekend is almost here. Following is the Daily Update with Highlights, the “Good Stuff”, Expanded Stories, statistics, trends and items of interest related to the novel coronavirus pandemic. -
China Confronts Covid-19
CHINA CONFRONTS COVID-19 By DAKE KANG and COLLEAGUES Associated Press STORY TK | ASSOCIATED PRESS 1 of 2 CRACKDOWN IN CHINA 1. CHINA DIDN’T WARN PUBLIC OF LIKELY PANDEMIC FOR 6 KEY DAYS April 15, 2020: Top Chinese ofcials secretly determined they were likely facing a pandemic from a new coronavirus in mid-January, ordering preparations even as they downplayed it in public. https://apnews.com/article/68a9e1b91de4fc166acd6012d82c2f9 2. CHINA DELAYED RELEASING CORONAVIRUS INFO, FRUSTRATING WHO June 3, 2020: Even as the World Health Organization publicly praised China, it privately complained about the lack of information it was getting on the new coronavirus. https://apnews.com/article/3c061794970661042b18d5aeaaed9fae 3. CHINA TESTING BLUNDERS STEMMED FROM SECRET DEALS WITH FIRMS Dec. 3, 2020: Secrecy and cronyism crippled China’s testing capacity in the early days of the outbreak, an Associated Press investigation has found. https://apnews.com/article/china-virus-testing-secret-deals-frms- 312f4a953e0264a3645219a08c62a0ad TABLE OF CONTENTS | ASSOCIATED PRESS https://apnews.com/article/68a9e1b91de4fc166acd6012d82c2f9 1 Xie Huanchi/Xinhua via AP Chinese President Xi Jinping talks by video with patients and medical workers at the Huoshenshan Hospital in Wuhan in central China’s Hubei Province in a video released March 10, 2020. April 15, 2020 China didn’t warn public of likely pandemic for 6 key days By ASSOCIATED PRESS Associated Press In the six days after top Chinese ofcials secretly determined they likely were facing a pandemic from a new coronavirus, the city of Wuhan at the epicenter of the disease hosted a mass banquet for tens of thousands of people; millions began traveling through for Lunar New Year celebrations. -
WHO: Global Coronavirus Deaths Rise for 1St Time in 6 Weeks 22 March 2021
WHO: Global coronavirus deaths rise for 1st time in 6 weeks 22 March 2021 the Philippines, Van Kerkhove said. The eastern Mediterranean region saw cases rise 8% percent, while the number of cases reported in the Americas and Africa declined. "I do want to mention that it had been about six weeks where we were seeing decreases in deaths," said Van Kerkhove. "And in the last week, we've started to see a slight increase in deaths across the world, and this is to be expected if we are to see increasing cases. But this is also a worrying sign." WHO emergencies chief Dr. Michael Ryan acknowledged an urge among the public in many Credit: Pixabay/CC0 Public Domain places to emerge from pandemic restrictions. Ryan insisted that any easing should coincide with measures such as strict case surveillance and high levels of vaccination, but said vaccines alone would A top World Health Organization expert on the not be enough. coronavirus pandemic said Monday the weekly global count of deaths from COVID-19 is rising "I'm afraid we're all trying to grasp at straws. We're again, a "worrying sign" after about six weeks of trying to find the golden solution: 'So we just get declines. enough vaccine and we push enough vaccine to people and that's going to take care of it,'" he said. Maria Van Kerkhove, technical lead on COVID-19 "I'm sorry, it's not." at the U.N. health agency, said the growth followed a fifth straight week of confirmed cases increasing © 2021 The Associated Press. -
COVID-19: Make It the Last Pandemic
COVID-19: Make it the Last Pandemic Disclaimer: The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Independent Panel for Pandemic Preparedness and Response concerning the legal status of any country, territory, city of area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Report Design: Michelle Hopgood, Toronto, Canada Icon Illustrator: Janet McLeod Wortel Maps: Taylor Blake COVID-19: Make it the Last Pandemic by The Independent Panel for Pandemic Preparedness & Response 2 of 86 Contents Preface 4 Abbreviations 6 1. Introduction 8 2. The devastating reality of the COVID-19 pandemic 10 3. The Panel’s call for immediate actions to stop the COVID-19 pandemic 12 4. What happened, what we’ve learned and what needs to change 15 4.1 Before the pandemic — the failure to take preparation seriously 15 4.2 A virus moving faster than the surveillance and alert system 21 4.2.1 The first reported cases 22 4.2.2 The declaration of a public health emergency of international concern 24 4.2.3 Two worlds at different speeds 26 4.3 Early responses lacked urgency and effectiveness 28 4.3.1 Successful countries were proactive, unsuccessful ones denied and delayed 31 4.3.2 The crisis in supplies 33 4.3.3 Lessons to be learnt from the early response 36 4.4 The failure to sustain the response in the face of the crisis 38 4.4.1 National health systems under enormous stress 38 4.4.2 Jobs at risk 38 4.4.3 Vaccine nationalism 41 5. -
Here There Are Plans Taken to Bring It to Light”
PANDA’S SCIENTIFIC ADVISORY BOARD SCOTT W. ATLAS SUCHARIT BHAKDI JAY BHATTACHARYA SUNETRA GUPTA SCOTT JENSEN MARTIN KULLDORFF MICHAEL LEVITT PAUL E. PETERSON ELLEN TOWNSEND MIKE YEADON OUR NETWORK “The truth ultimately prevails where there are plans taken to bring it to light” George Washington A WORLD GRIPPED BY FEAR THE FALSE NARRATIVE BEHIND THE A deadly novel virus is sweeping the planet. FEAR Nobody is immune and there is no cure. Asymptomatic people are major drivers of disease. So we have to lock down and wear masks until everyone is vaccinated. Anyone who challenges this narrative is a danger to society. UNJUSTIFIED FEAR IN THE FACE OF REALITY A virus that presents high risk to few and negligible risk to most hit some regions. THE REALITY Few are susceptible to severe disease. There are several available treatments. Asymptomatics are not major drivers of disease. Lockdowns and mask mandates, never recommended before, were tried. They haven’t worked and caused great harm. The vulnerable were hurt instead of helped. CFR= Deaths/ diagnosed A DEADLY cases VIRUS? IFR= Deaths/ total infected cases TEDROS ADHANOM “Reported case fatality rates, like the official 3.4% rate from the WHO, cause horror — and are NOT SO meaningless.” DEADLY 7 M A R C H 2 0 2 0 A review of 61 seroprevalence studies IFR: median is 0.23%, 0.05% for those below 70 1 4 O C T 2 0 2 0 JOHN IOANNIDIS NOT SO “The consequences of Covid-19 may DEADLY ultimately be more akin to those of a severe seasonal influenza” 2 6 M A R C H 2 0 2 0 ANTHONY FAUCI YOUNGER THAN 19 Y -
COVID-19 Virtual Press Conference
COVID-19 Virtual Press conference 2 October 2020 Speaker key: FC Fadela Chaib TAG Dr Tedros Adhanom Ghebreyesus MI Michelle MK Dr Maria Van Kerkhove MR Dr Michael Ryan BA Dr Bruce Aylward AN Anias KA Katrine GA Gabriela JA Jason KO Konstantin SS Dr Soumya Swaminathan LA Laurent AS Ashley EC Dr Emer Cook JO John MC Michael 00:00:49 FC Hello, everybody. I am Fadela Chaib, speaking to you from the Geneva WHO headquarters and welcoming you to our global COVID-19 press conference today, Friday, October 2nd. I'm sorry for the delay in starting this press conference. Today the briefing will focus on the COVID-19 epidemiological situation and overview. Before we go deep in developing this important aspect Dr Tedros, our Director-General, will address you first. Joining him in the room are Dr Mike Ryan, Executive Director, Emergencies Programme, Dr Maria Van Kerkhove, Technical Lead for COVID- 19, Dr Mariangela Simao, Assistant Director-General, Access to Medicines and Health Products, Dr Soumya Swaminathan, WHO Chief Scientist, and Dr Bruce Aylward, Senior Advisor to the Director-General and Lead on the ACT Accelerator. Welcome, all. This briefing is being translated simultaneously into the six official UN languages plus Portuguese and Hindi. Now without further ado I will hand over to Dr Tedros for his opening remarks. Dr Tedros, you have the floor. TAG Thank you, Fadela. Good morning, good afternoon and good evening. Overnight we heard that the President of the United States of America, Donald Trump, and First Lady, Melania Trump, tested positive for COVID-19. -
The Potential Role of Extracorporeal Membrane Oxygenation
Opinion Preparing for the Most Critically Ill Patients With COVID-19 VIEWPOINT The Potential Role of Extracorporeal Membrane Oxygenation Graeme MacLaren, The novel coronavirus has now infected tens of thou- greater. To address this, prompt mobilization of exist- MSc sands of people in China and has spread rapidly around ing registries and clinical research groups should help fa- Cardiothoracic the globe.1 The World Health Organization (WHO) cilitate the systematic collection of data. For example, Intensive Care Unit, has declared the disease, coronavirus disease 2019 the Extracorporeal Life Support Organization (ELSO) National University Health System, (COVID-19), a Public Health Emergency of International Registry is being adapted to acquire new information Singapore. Concern and released interim guidelines on patient about COVID-19 and prospective observational studies management.2 Early reports that emerged from Wuhan, are under way. Dale Fisher, MBBS the epicenter of the outbreak, demonstrated that the ECMO does not provide direct support for organs Division of Infectious clinical manifestations of infection were fever, cough, other than the lungs or heart beyond increasing Diseases, University Medicine Cluster, and dyspnea, with radiological evidence of viral systemic oxygen delivery and mitigating ventilator- National University pneumonia.3,4 Approximately 15% to 30% of these pa- induced lung injury. A substantial proportion of criti- Health Systems, tients developed acute respiratory distress syndrome cally ill patients with COVID-19 appear to have devel- Singapore; and 3 Department of (ARDS). The WHO interim guidelines made general rec- oped cardiac arrhythmias or shock, but it is unknown Medicine, Yong Loo Lin ommendations for treatment of ARDS in this setting, in- how many have or will develop refractory multiorgan School of Medicine, cluding that consideration be given to referring pa- failure, for which ECMO may be of more limited use. -
C56c4539 6941 4Fe2 93Ff 3Fd5f7f198c8ics COVID 19 Güncel
Evrak Tarihi ve Sayısı: 20.01.2021-282 *BELCKK62* c1 Sayı : 38591462-010.07.03-2021-282 20.01.2021 Konu : ICS COVID-19 Güncel Duyurusu Sirküler No: 78 Sayın Üyemiz, Uluslararası Deniz Ticaret Odası (International Chamber of Shipping-ICS) tarafından gönderilen 18 Ocak 2021 (Ek-1) ve 11 Ocak 2021 (Ek-2) tarihli yazılarda, Dünya Sağlık Örgütü'nün (World Health Organization-WHO) yayınladığı, bütün ülkeler tarafından bildirilen "Yeni Koronavirüs" (Covid-19) akut solunum yolu hastalık vaka tablosunu içeren güncel istatistiki bilgiler Odamıza iletilmiştir. Bahse konu yazılarda Covid-19 vakalarının, hastaneye yatan hasta ve vefat sayılarının Avrupa ve Amerika'da önemli ölçüde artmaya devam ettiği, 18 Ocak 2021 tarihi itibarıyla toplam 93.194.922 Covid-19 vakası tespit edildiği, birçok ülkenin halihazırda uygun test ekipmanına sahip olmadığı için tüm vakaların rapor edilemediği ve bu nedenle sayıların artacağı belirtilmekte olup, rapor tarihi itibarıyla en fazla Covid-19 vakası tespit edilen ilk 12 ülke, Covid-19 salgını vaka ve vefat sayılarının olduğu tablo ve ülkeler hakkında güncel bilgiler bulunmaktadır. Ayrıca yazılarda, Covid-19 salgınıyla mücadele kapsamında ülkeler tarafından sürdürülen aşı programları hakkındaki gelişmelere ait bilgiler ile aşağıdaki hususlar yer almaktadır: - UN COVAX programında aşıların bulunabilirlik durumunu özetleyen ve günlük olarak güncellenen veri tabanına UNICEF web sitesinden erişilebilmektedir. Anlaşma yapıldıkça güncellenen tabloyla birlikte, hangi ülkelerde sözleşmelerin olduğu, satın alınan miktarların -
MRC Centre for Outbreak Analysis and Modelling
Centre for Outbreak Analysis and Modelling MRC Centre for ANNUAL REPORT Outbreak Analysis and Modelling www.imperial.ac.uk/medicine/outbreaks 2012 The Centre specialises in quantitative epidemiology encompassing mathematical modelling, statistical analysis and evolutionary epidemiology, to aid the control and Director’s message treatment of infectious diseases. April 2013 sees the Centre renewed for a second 5-year Consortium (led by Tim Hallett) and the Vaccine Modelling term, after we received an unprecedented 10 out of 10 Initiative – are up for renewal. However, grants are only score from the MRC subcommittee, which assessed the one aspect of the relationship. As important are the close performance of the Centre over its first term. Just as the working relationships between staff in the Centre and the work of the Centre over that time has been very much a Foundation, which sees our research increasingly used to team effort, so was the success of the renewal. inform Foundation strategy and delivery. The last few months have seen us start to drive through Despite its title, the Centre’s mission rapidly evolved to our strategy for the next 5 years. A crucial aspect of this encompass delivering innovative epidemiological analysis is to boost capacity in key research areas. It is therefore not only of novel infectious disease outbreaks, but also of my pleasure to welcome new academic staff into the endemic diseases of major global health significance. Our Centre. Xavier Didelot joined us last year as a lecturer in work on polio, malaria and HIV reflects this. However, the pathogen genetics, and our expertise in evolutionary and last few months have highlighted the ongoing relevance of genetic research will be further boosted this year by the our original mission to enhance preparedness and response recruitment of at least one additional member of academic to emerging disease threats. -
Assessing the Impact of the COVID-19 Pandemic on Nosocomial Transmission of Carbapenem-Resistant Organisms (CRO)
Assessing the impact of the COVID-19 pandemic on nosocomial transmission of Carbapenem-resistant organisms (CRO) Dr Kalisvar Marimuthu Senior Consultant, Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore Senior Consultant, National Centre for Infectious Diseases, Singapore Director, Infection Prevention and Control Office, Woodlands Health Campus, Singapore Adj. Asst. Prof. of Medicine, National University of Singapore, Singapore Contributors: Professor Paul Ananthraj Tambyah, National University of Singapore Professor Dale Andrew Fisher, National University of Singapore Professor Stephan Harbarth, Prevention and Control of Infection, Geneva University Hospital A/Prof Oon Tek Ng, National Centre for Infectious Diseases, Tan Tock Seng Hospital, Nanyang Technological University A/Prof Brenda Ang Sze Peng, Tan Tock Seng Hospital, Singapore Positive and negative impact of COVID-19 on CRO • Resource diversion resulting in: • Increased awareness of IPC principles • Interruption of infection prevention • and control (IPC) surveillance and Increase awareness of importance of audits hand hygiene • Interruption of screening for • Possibility of increase in funding for asymptomatic carriers (lab resources) IPC post-pandemic • Prioritization of isolation facilities for COVID-19 patients • Disruption to health services resulting • Slowing or complete cessation of in reduction in non-COVID-19 AMR research hospitalization • Possible increase in antimicrobial utilization for COVID-19 related respiratory illnesses Possible negative -
Analyzing the Effect of Relaxing Restriction on the COVID-19
medRxiv preprint doi: https://doi.org/10.1101/2021.04.19.21255759; this version posted April 20, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license . Analyzing the effect of relaxing restriction on the COVID-19 outbreak for some US states Mahir Demir Department of Fisheries and Wildlife/Quantitative Fishery Center, Michigan State University East Lansing, MI, 48823 USA [email protected] ibrahim Halil Aslan Department of Mathematics, Batman University, West Ramada Batman, 72000, Turkey [email protected] Suzanne Lenhart Department of Mathematics, University of Tennessee Knoxville, TN, 37996 USA [email protected] April 20, 2021 Abstract The ongoing pandemic disease COVID-19 has caused worldwide social and financial disrup- tion. As many countries are engaged in designing vaccines, the harmful second and third waves of COVID-19 have already appeared in many countries. To investigate changes in transmission rates and the effect of social distancing in the USA, we formulate a system of ordinary differential equations using data of confirmed cases and deaths in these states: California, Texas, Florida, Georgia, Illinois, Louisiana, Michigan, and Missouri in the USA to be able to investigate changes in transmission rates of the outbreak and effect of social distancing. Our models and the corre- sponding parameter estimations show social distancing reduces the transmission by 60% to 90%, and thus obeying the movement restriction rules plays a crucial rule to reduce the magnitudes of the outbreak waves. -
Nationally-Led Simulation to Test Hospital Systems
Simulation for Outbreak Preparedness—Lionel HW Lum et al 332 Editorial Pandemic Preparedness: Nationally-Led Simulation to Test Hospital Systems 1 2 3 2 Lionel HW Lum, MBBS, MRCP (UK), Hishamuddin Badaruddin, BMBS, MPH, FAMS, Sharon Salmon, BN, MPH, PhD, Jeffery Cutter, MBBS, 4 1,5 MMed (PH), FAMS, Aymeric YT Lim, MBBS, FRCS (Glasgow), FAMS, Dale Fisher, MBBS, FRACP, DTM&H Introduction of requirements for hospital preparation, encompassing in- Cities that receive large numbers of international travellers house evaluations using “table-top” (theoretical) exercises, are particularly vulnerable to outbreaks of emerging quality and process improvement “walkabouts”, and infectious disease with pandemic potential.1 Secondary department-specific simulation exercises. transmission of Ebola virus disease (EVD) occurred when To mitigate the threat posed by EVD, the Ministry of Health travellers from West Africa infected healthcare workers (MOH), Singapore undertook a series of “walkabouts” to in Europe and the United States in 2014.2,3 Middle East assess institutional readiness in most major public and respiratory syndrome (MERS) coronavirus has also caused private hospitals across the country during the latter part of secondary outbreaks due to travel by infected individuals. 2014. To further test and facilitate enhancement of systems, While most of these distant outbreaks of MERS have to MOH subsequently undertook full scale national simulation date been quickly confined, South Korea experienced 185 exercises collectively called Exercise Sparrowhawk. laboratory-confirmed cases involving 5 generations of 4 transmission over 6 weeks. In Singapore, the Nipah virus National Simulation Exercise in 1998 to 1999, severe acute respiratory syndrome (SARS) coronavirus in 2003 and influenza A/H1N1 in 20095 not Prior to the exercises, hospitals were required to submit only had a major impact on the health of its population a copy of their hospital preparedness standard operating and notably its healthcare workers, but also more broadly, procedures to MOH for review.