bioRxiv preprint doi: https://doi.org/10.1101/612077; this version posted April 17, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Long noncoding RNAs sustain high expression of exogenous Oct4 by sponging miRNA during reprogramming Qingran Kong*†1, 2, Xiaolei Zhang†1, Jiaming Zhang†1, Kailun Zheng1, Heng Zhang1, Xixiang Pei3, Zhi Yin1, Duancheng Wen*2, Zhonghua Liu*1 1Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin, 150030, Heilongjiang Province, China 2Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA 3Harbin Botai Bio-Tech Co., Ltd., No. 59 mucai Street, Xiangfang District, Harbin, 150030, Heilongjiang Province, China *Corresponding: Zhonghua Liu: College of life science, North-east Agricultural University, No.59 Mucai Street, Harbin, Heilongjiang 150030, China; E-mail:
[email protected]; Tel: +86-045155191729. Qingran Kong: College of life science, North-east Agricultural University, No.59 Mucai Street, Harbin, Heilongjiang 150030, China; E-mail:
[email protected]; Tel: +86-045155191747; Duancheng Wen: Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA;
[email protected]; Tel: (212) 746-2017; † These authors contributed equally to this work Running title: linc/circRNAs sponge miRNAs during reprogramming bioRxiv preprint doi: https://doi.org/10.1101/612077; this version posted April 17, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder.