Welcome Note…………………………………………………….……...………...... 2 The Academy………………………………………………………………………………...... 3 Secretariats and Registration Scientific Secretariat……………………………………………………………………………...... 4 Organizing Secretariat………………………………………………………………………...... 4 Congress Secretariat Desk.………………………………………………………………...... 4 Registration Fees………………………………………………………………………………………….... 5 Scientific Information Format of the Congress …………………………………………………...... 7 Congress on-line………………………………………………………… ……………………………...... 7 Computer Projection…………………………………………………… ………………………………...... 8 Preview Room.…………………………………………………………….……………………………...... 8 Oral Presentation…………………………………………………………………………………………..... 8 Poster Session……………………………………………………………………………………………..... 8 Poster Awards……………………………………………………………………………………………...... 8 General Information Congress venue…………………………………………………………………………………………...... 9 Conference halls…………………………………………………………...... 9 List of Contents Secretariat………………………………………………………………………………………………...... 9 Dedicated rooms…………………………………………………………...... 9 Congress on-line ………………………………………………………………………………………...... 9 Exhibition area…………………………………………………………………………………………...... 9 Lunch points……………………………………………………………………………………………...... 9 Coffee……………………………………………………………………...... 9 Official language…………………………………………………………………………………………...... 9 Insurance………………………………………………………………………………………………...... 9 Badges……………………………………………………………………………………………………...... 11 Certificate of attendance.…..……………………………………………………………………………..... 11 Customer satisfaction..…………………………………………………………………………………...... 11 Transfers…………………………………………………………………………………………………...... 11 Personal data protection – law n. 196/2003..……………………………...... 11 Sponsors and Exhibitors Exhibition Area Map..…………………………………………………………………………………...... 12 Sponsors and Exhibitors………………………………………………………………………………….... 13 Continuous Medical Education UEMS Credits (Europe)…………………………………………………………………………………...... 21 Crediti ECM………………………………………………………………………………………………...... 21 ECM Credits for Italian Delegates………………………………………...... 22 Social Programme Social Programme for participants……………………………………………………………………...... 23 Social Programme for registered accompanying persons………………………………………...... 23

Scientific Programme………………………………………………...... 25 Thursday, March 5th………………………………………………...... 26 Friday, March 6th………………………………………………...... 39 Saturday, March 7th ………………………………………………...... 53 Sunday, March 8th………………………………………………...... 68

Posters………………………………………………...... 74

Programme at-a-glance………………………………………………...... 92

1 Dear Friends,

Welcome to Venice to the 13th Congress on Human Reproduction.

The congress has been dedicated to the leading figure of Luigi Mastroianni, a master in science and a great teacher extending his education not only to American gynaecologists but also to those working all over the world.

The congress will focus on new aspects in contraception, induction of ovulation, assisted procreation technologies and all other areas of reproductive medicine starting from genetics and stem cells until menopause.

Great attention has also been devoted to specific topics greatly developing in these last years such as cryopreservation and vitrification for gametes preservation, in vitro maturation of oocytes and new horizons in gynaecological endocrinology and gynaecological oncology. Strategic areas such as endometriosis, sexual medicine, menopause and polycystic ovary disease will be largely discussed. The congress, structured with plenary lectures and plenary sessions, has been also enriched by seven round tables and 11 free communication sessions and by the presence of specific symposia organized by the Portuguese Society of Reproductive Medicine, the International Society of Gynaecological Endocrinology, the Italian Society of Embryology Reproduction and Research, the International Society of Psychosomatics Obstetrics and Gynaecology.

The congress will be concluded by a discussion on the importance of National and European Registries in Assisted Reproduction Technologies.

Last but not least being March 8th the Woman’s Day there will be a session in Italian, open to all venetian citizens on “Ethical aspects of Human Reproduction: from contraception to assisted procreation”.

Wishing you a successful and fruitful work on behalf of the Academy of Human Reproduction.

Welcome Note Welcome Yours sincerely, Joseph G. Schenker Andrea R. Genazzani President of the Academy President of the Congress Honorary President of the Congress

2 The International Academy of Human Reproduction

President Joseph G. Schenker (Israel)

Honorary Chairmen †Luigi Mastroianni, USA Sheldon Segal (USA) †Kurt Semm (Germany)

Secretary Liselotte Mettler (Germany)

Actual Members Biran Affandi, Indonesia Pedro N. Barri, Spain Giuseppe Benagiano, Italy Henning M. Beier, Germany

Zion Ben-Rafael, Israel The Academy Ariff Bongso, Singapore Stuart Campbell, UK Jean Cohen, France Elsimar M. Coutinho, Brazil George K. Creatsas, Greece Luigi C. Devoto, Chile Klaus Diedrich, Germany Gian Carlo Di Renzo, Italy Mahmoud Fathalla, Egypt Rene Frydman, France Andrea R. Genazzani, Italy Victor Gomel, Canada Lars Hamberger, Sweden M. Hansotia, India David L. Healey, Australia Wolfgang Holzgreve, Switzerland Howard Jacobs, UK Howard Jones, USA Rudolf Klimek, Poland Gabor T. Kovacs, Australia Asim Kurjak, Croatia Neri Laufer, Israel Stelios Michalas, Greece Takeshi Mori, Japan Frederick Naftolin, USA Soon-Chye Ng, Singapore John Sciarra, USA Markku T. Seppala, Finland Zeev Shoham, Israel Joe Leigh Simpson, USA Jerome F. Strauss III, USA Shuetsu Suzuki, Japan Seang L. Tan, Canada Alan O. Trounson, Australia Petrache Vartej, Romania Edward Wallach, USA L. Wei-xiong, China

3 Scientific Secretariat P.G. Artini, V. Cela, A. Gadducci, P. Monteleone, T. Simoncini, V. Valentino Dept. of Reproductive Medicine and Child Development Division of Gynecology and Obstetrics “P. Fioretti” - University of Pisa Via Roma 35 – 56126 Pisa – Italy Phone +39 050 503985 Fax +39 050 220 7028 E-mail: [email protected]

Organizing Secretariat Biomedical Technologies srl Web Site: www.biomedicaltechnologies.com

Operative Office: Via Trieste 1 – 56126 Pisa – Italy Phone: +39 050 501934 Fax: +39 050 501239 E-mail: [email protected]

Main Office, Accounting Department and Hotel Booking: Via P. Cugia 1 – 09129 Cagliari – Italy Phone: +39 070 340293 Fax: +39 070 307727 E-mail: [email protected]

Congress Secretariat Desk The Congress Secretariat is located on the ground floor. The Secretariat observes the following opening hours:

Wednesday March 4 from 14.00 to 19.00 Thursday March 5 from 08.00 to 19.00 Friday March 6 from 08.00 to 19.00 Saturday March 7 from 08.00 to 19.00 Sunday March 8 from 08.00 to 13.30 Secretariats and Registration Secretariats and Registration

4 Secretariats and Registration

Registration fees (20% VAT included) Before 15/01/2009 After 16/01/2009

Delegate € 450,00 € 550,00

Developing Countries and East Europe € 350,00 € 400,00 (WHO List)

Technical delegate* € 250,00 € 300,00

Accompanying person € 120,00 € 120,00

Daily registration fee € 200,00

*Residents in training, nurses and technicians. Official certificate must be submitted.

Registration fee includes: Congress Kit Book of Abstracts in CD- Rom version Access to all sessions and exhibition area CME/ ECM credits Password to access the Congress on-line. Opening and Closing Ceremony at the Congress Venue Get-Together Evening at La Fenice Theatre Lunches

Registration fee for accompanying persons includes: Opening and Closing Ceremony at the Congress Venue Access to the exhibition area Half-day Venezia City Tour

Daily registration fee includes: Congress kit Access to all sessions and exhibition area 1 lunch

5 Secretariats and Registration Secretariats and Registration

6 Format of the Congress

Wednesday, March 4 th, 2009 14.00/19.00 Registration Thursday, March 5 th, 2009 08.30/19.00 Registration 10.00/11.00 Opening Ceremony at the Congress Venue and Opening Lecture

11.00-19.00 Plenary Sessions Plenary Lectures Symposia Round Tables Oral Presentations Educational Course 19.30/22.00 Get-Together Evening at La Fenice Theatre

Friday, March 6 th, 2009 08.30/19.00 Plenary Sessions Scientific Information Plenary Lectures Symposia Oral Presentations Educational Course in Italian language Saturday, March 7 th, 2009 08.30/17.00 Plenary Sessions Plenary Lectures Symposia Oral Presentations 17.00/19.00 Poster Session and Venetian Cocktail

Sunday, March 8 th, 2009 08.30-13.30 Plenary Sessions Plenary Lectures Symposia Oral Presentations 13.30-13.45 Closing Ceremony and Poster Awards at the Congress Venue

Congress on-line

The 13th World Congress on Human Reproduction is available in multimedia format. It consists in recorded presentations of the Congress enjoyable through the web with any internet connection, starting from normal 56 Kb analogical connection. Typing in your personal password, that will be given to you at the moment of the on-line registration, you can access all the recorded scientific sessions and view the sequence of the slides of the presentations while hearing the speaker’s voice; it will be possible to stop, to go back, or see again what you consider more interesting at any time.

Kindly remember to always use your Access Code for the Congress On-line

The following contents will be available:

• Plenary Lectures • Plenary Sessions • Sponsored Symposia

Click on the access banner from the following web sites: www.biomedicaltechnologies.com www.humanrep2009.com

7 Computer projection Computer projection is provided in all conference rooms via direct link with the preview room. No projection through own computers is allowed. Kindly bring your presentation on a multimedia support (CD-Rom, Pen Drive) as a Powerpoint file. Please remember that the first slide of your presentation has to show your photo along with the name underneath. No other software are accepted. No Slide Projector is provided.

Preview Room The Preview Room is located behind the Exhibition and Poster Area. Speakers are kindly requested to hand over their PowerPoint presentation at the Preview room at least one hour before their session. Speakers presenting in the early morning sessions should ensure that they have handed over their slides during the previous afternoon.

Oral Presentation Oral Presentations will last about 5 minutes each plus 2 minutes discussion. The presenters are kindly requested to respect the time allotted for each presentation.

Poster Session Posters must be set up in the afternoon of March 5, and dismantled them not before Sunday March 8. Poster Boards are available for the selected posters. The size of the boards is 250 (height) x 100 (width) cm. Participants have the opportunity to study all the selected posters during the Congress Days.

The Poster Session will take place on Saturday March 7 from 17.30 to 19.00. During the official Poster Session, Poster Authors should stand by their Posters for presentation and discussion. The Poster Area (Venetian Foyer) is open according to the schedule of the scientific sessions. The organizers cannot be held responsible for posters not removed on time.

Kindly remember that the your attendance to to the Closing Ceremony is needed to know the winners

Scientific Information Poster Awards The Scientific Committee will select the three best posters that will be awarded with Euro 500,00 each. The selected posters will be marked on Saturday, March 7 afternoon. The Award Ceremony will take place on Sunday, March 8th at 13.45, during the Closing Ceremony. At least one the authors for each selected poster is requested to be present during the Ceremony, otherwise the award will not be assigned.

8 Congress Venue The Congress will take place at the Hilton Molino Stucky Hotel: Giudecca 810 30133 Venice, Italy Tel. +39 041 2723311 Fax +39 041 2723308 Website: www.molinostuckyhilton.com

Conference Halls and Meetings Rooms Hall Venice 1 Ground floor Hall Venice 2 Ground floor Hall Venice 3 Ground floor Hall Goldoni-Vivaldi First floor Hall Casanova First floor Press Room First floor Speakers Room First floor Preview Room Ground floor General Information

Secretariat The Secretariat is located on the ground floor near the exhibition area.

Dedicated Rooms Private Meeting Room Hall Palanca Ground floor Presidential Room Hall Zitelle Ground floor Faculty Room Hall Bellini First floor Press Room Hall Pisani First floor

Congress on-line An Information Point is available in the Exhibition Area - Biomedical Technologies Stand - for assistance, information, access codes and any other questions concerning the Congress on-line.

Exhibition area Exhibits are open according to the schedule of the scientific sessions and located at the enetianV Foyer.

Lunches On Thursday March 5th, Friday March 6th and Saturday March 7th, from 13.00 to 14.30, lunches together with a glass of wine from Scopone Wineries (Montalcino) will be served in the Exhibition Area.

Official Language Official language of the Congress is English.

Insurance The Congress Organizers cannot accept liability for personal injuries, loss or damage to property belonging to Congress delegates (or their accompanying persons), either during or as a result of the Congress or during their stay in Venice. It is therefore recommended that delegates arrange their own personal health, accident and travel insurance.

9 General Information General

10 Badges All registrants including registered accompanying persons will receive a badge. Your personal badge allows you access to all Session, Exhibition Area and Social Events. Please remember to always wear your badge, also during the social events. If you have lost your badge, a new one can be purchased at the Congress Secretariat. Kindly remember to always wear your badge, also during the social events

Certificate of Attendance The Certificates of Attendance are available at the CME/Certificates Desk from Saturday morning at 10.00. Your badge and filled out Customer Satisfaction Form are needed to obtain the Certificate. Please note that your badge and filled out Customer Satisfaction Form are needed to obtain your Certificate of Attendance Customer Satisfaction You will receive the Customer Satisfaction Form together with your congress kit.

Please do not ignore it. It is a Compulsory Service as BiomedicalTechnologies is Quality Certified and General Information moreover you help us to improve our services. Please hand it back upon receiving your Certificate of Attendance at the CME/Certificates Desk.

Transfers Private “vaporetto” shuttle service will be available during the Congress works from S. Marco to Hilton Molino Stucky Hotel as follows:

07.45 - 08.00 – 08.30 – 08.45 - 09.15 San Marco – Hilton Molino Stucky Thursday 5th 19.00 Hilton Molino Stucky – La Fenice 07.45 - 08.00 – 08.30 – 08.45 - 09.15 San Marco – Hilton Molino Stucky Friday 6 th 19.30 - 19.45 Hilton Molino Stucky - San Marco

07.45 - 08.00 – 08.30 – 08.45 - 09.15 San Marco – Hilton Molino Stucky Saturday 7 th 19.15 - 19.30 Hilton Molino Stucky – San Marco

07.45 - 08.00 – 08.30 – 08.45 - 09.15 – San Marco – Hilton Molino Stucky Sunday 8 th 10.00 13.30 – 14.00 Hilton Molino Stucky – San Marco

Tranfers timetable will be available at the congress with registration.

Personal Data Projection – Law no. 196/2003 Personal data collected directly and/or through third parties by controller and processor Biomedical Technologies. Main Office in Cagliari Via Cugia 1, are processed in printed, computing and telematic form for fulfilling contractual and lawful obligations as well as for the effective handing of business relations. The email addresses provided may be used by Biomedical Technologies to send advertising materials on events similar to those subject of the present business relations. The non-submittal of data, where no compulsory, will be evaluated from case to case by the controller and the resulting decisions to be made will take into account the importance of the required data in respect of the business relations, management. Data may be disclosed in Italy and/or abroad, strictly in accordance with the above-mentioned purposes, and consequently processed, only in relation to the mentioned purpose, by other persons: professionals and consultants as well as by persons allowed to access to your personal data according to National or Community regulations. If necessary, for the above-mentioned reasons, your data may be disclosed to third parties. For the same reasons, our partners and/or employees may process your data in their capacity of executors or processors. The persons concerned may exercise all the rights set forth in art. 7 of L. n. 196/2003 (including the rights of data access, corrections, updating, objects to data processing and cancellation). The processor “pro tempore” is the legal representative of the company.

11 Sponsors and Exhibitors

12 Sponsors and Exhibitors

The organizers of the 13th World Congress on Human Reproduction wish to acknowledge the major support given as Platinum Sponsor to the Congress:

Bayer Schering Pharma IBSA Institut Biochimique SA

The organizers of the 13th World Congress on Human Reproduction wish to acknowledge the support given as Sponsor to the Congres: Sponsors and Exhibitors

American Association of Clinical Endocrinologists Bayer S.p.A.

BioCare Europe SAS Carl Zeiss MicroImaging GmbH

Cryo Biosystem Cryo-Save Italia Srl

Ferring Pharmaceuticals Grünenthal GmbH

MDT Medical Development & Technology BV Karl Storz Gmbh & Co.KG

Merck Serono Spa Medicult Italia Spa

Nikon Instruments Spa Nanopoint, Inc

Schering Plough Corporation Pantarhei Bioscience BV

Solvay Pharmaceuticals Marketing&Licensing AG Schering Plough Spa

Special thanks for the support in promoting the event and the commitment to the world of scientific publishing:

CIC Edizioni Internazionali Informa Healthcare

Elsevier Health Services S. Karger AG

Exhibition Area Exhibits are located at the Venetian Foyer

Opening hours: March, Thursday 5 th from 10,00 to 19,00 March, Friday 6 th from 08.30 to 19.00 March, Sunday 7 th from 08.30 to 19.00 March, Sunday 8 th from 08.30 to 13.00

13 List of Sponsor and Exhibitors

American Association of Clinical Endocrinologists 245 Riverside Avenue, Suite 200 Jacksonville, FL 32202 Tel: +904-353-7878 - fax:+ 904-353-8185 Website: www.aace.com AACE is a medical professional community of clinical endocrinologists committed to enhancing its members’ ability to provide the highest quality of care. AACE, established in 1991, is the country’s largest professional organization of clinical endocrinologists. Its members consist of more than 6,000 clinical endocrinologists devoted to providing care for patients with endocrine disorders.

Bayer Schering Pharma AG Müllerstr. 178, D-13342 Berlin, Germany Tel: +49-30-468-1111 - Fax: +49-30-468-18074 Website: www.bayerscheringpharma.de Bayer Schering Pharma is one of the ten largest specialty pharmaceutical companies in the world. We market our products in more than 100 countries, and generated sales of over € 10 billion in 2007. Over 37,000 employees currently work for Bayer Schering Pharma worldwide – more than 5,000 in research and development alone. With our products, we aim to help improve people’s quality of life. To achieve this, we concentrate on the research and development of innovative drugs and novel therapeutic approaches. At the same time, we are constantly improving established products. In this context, Bayer Schering Pharma uses experience gained in more than a century in the business. Our focus is on four business areas, in which we make essential contributions to medical progress: Diagnostic Imaging General Medicine Specialty Medicine Women’s Healthcare

Bayer S.p.a. Viale Certosa 130 - 20156 Milano, Italia Tel. +39 02.39781 www.bayerscheringpharma.it

BioCare Europe SAS Via Siracusa 15 00161 Roma (Italy) Tel: 06-44240341 - Fax: 06-44240358

Sponsors and Exhibitors Email: [email protected] Website: www.biocareeurope.com BioCare Europe is a supplier of consumer materials (needles, catheters, glass tubes) and equipments for the IVF laboratory

Carl Zeiss MicroImaging GmbH Carl Zeiss Group Carl-Zeiss-Promenade 10 07745 Jena Tel: +49 36 41 64 34 00 and +49 551 50 60-596 - Fax: +49 36 41 64 31 44 and +49 551 50 60-574 E-Mail: [email protected] Website: www.zeiss.de/micro As a manufacturer and supplier of microscopy solutions and systems for research, laboratories, routine and industrial applications, the company is one of the global market leaders in this field. Carl Zeiss stands for highest quality in the complete range from routine microscopes to complex laser scanning microscopes.

14 CIC Edizioni Internazionali Corso Trieste 42, 00198 Roma, Italy Tel: +39 06 8412673 - Fax: +39 06 8412688 Email: [email protected] Website: www.gruppocic.it For several decades CIC Edizioni Internazionali has been a leading publishing house in the different specialties on medicine and surgery. We publish both books and periodicals, and in particular we are specialized in the publication of books and congress proceedings regarding Gynecology and Obstetrics.

Cryo Biosystem 29 rue Tronchet 75008 Paris Tel: +33 149 240 505 - Fax: +33 149 240 501

Email: [email protected] Sponsors and Exhibitors Website: www.cryobiosystem.com Cryo Bio System, the expert in cryopreservation with its CBS™ High Security straw concept, is now worldwide recognized for its HSV High Security Vitrification kit, a reliable, fast and secure device for oocyte and embryo vitrification. Cryo Bio System also manufactures IUI/ET catheters and brand-new equipment for the ART and Biobanking markets.

Cryo-Save Italia Srl Via Giulio Vincenzo Bona, 133 – 00156 Roma Numero Verde 800 438 270 Tel. 06 41 11 346 - Fax 06 41 22 97 02 Email: [email protected] Website: www.cryo-save.com Cryo-Save Group is an International Company in the field of biotechnology and specialised in the separation, isolation and cryo-preservation of adult stem cells and the development of innovative therapeutic treatments by the use of stem cells. The company was founded in 2000 and is present in 38 countries. It is the leader stem cell bank in Europe thanks to the preservation of stem cells of about 100.000 children.

Elsevier Health Services Radarweg 29, 1043 NX Amsterdam, the Netherlands Tel: +31 (0)20 485 3122 - Fax:+31 (0)20 485 3249, Website: www.elsevier.com Elsevier is the leading international publisher of medical journals, books and electronic products. Imprints include Masson, Churchill Livingstone, Mosby and Saunders. Elsevier is the publisher of the EMC Encyclopedia and of Yen & Jaffe’s Reproductive Endocrinology.

Ferring Pharmaceuticals Ferring International Center SA Chemin de la Vergognausaz 50 1162 Saint-Prex, Switzerland Tel:+41 (0) 58 301 0000 Website: www.ferring.com Ferring is a Swiss-based research driven, specialty biopharmaceutical group active in global markets. The company identifies, develops and markets innovative products in the areas of fertility, gynaecology, endocrinology, gastroenterology and urology. In recent years Ferring has expanded beyond its traditional European base and has offices in over 40 countries. To learn more about Ferring or its products please visit www.ferring.com and come to the FERRING booth.

15 Grünenthal GmbH 52099 Aachen, Germany Tel:+49 241 569-2858 Tel:+49 241 569-1486 Email: [email protected], Website: www.grunenthal.com, Website: www.belara.com Grunenthal is an expert in pain therapy and gynaecology and a pioneer in intelligent, user-friendly drug delivery technologies. Founded in 1946, the company discovers, develops, produces and markets high therapeutic value pharmaceuticals. Grunenthal is an independent, family-owned German company operating with affiliates in 32 countries, employing about 1900 people in Germany and 5,300 worldwide. In 2007, Grunenthal achieved revenues of 846 million Euros. Grunenthal has been carrying out research, development, and marketing of contraceptives for more than 40 years, initially driven by the German home market. There the oral contraceptive Belara® is ranked no 2 in its market segment and no 1 among teenage users. Today Belara® is available in over 30 countries worldwide. Dedicated to gynaecology Grunenthal will continue investing in research and development of innovative contraceptive methods. Grunenthal, originator of the analgesic tramadol (Tramal®), also introduced the buprenorphine patch Transtec®, the fixed analgesic combination Zaldiar® (paracetamol/tramadol), and the 5% lidocaine medicated plaster Versatis®. Tapentadol, a novel, centrally acting analgesic, is the latest innovation coming out of Grunenthal’s R&D pipeline.

IBSA Institut Biochimique SA Via del Piano, P.O. Box 266, 6915 Pambio-Noranco, Lugano, Switzerland Tel: +41 58 360 10 00 - Fax:+41 58 360 16 47 Email: [email protected], Website: www.ibsa-international.com IBSA is an international pharmaceutical company headquartered in Lugano, Switzerland, delivering different therapeutic solutions for follicular stimulation and luteal support. IBSA’s unique, whole in-house manufacturing cycle provides a full range of highly purified, human-type gonadotrophins: hFSH (Fostimon), hMG and hCG. Other company’s franchises include osteoarthritis, pain-management, dermatology and thyroid diseases.

Informa Healthcare Informa Healthcare Telephone House 69-77 Paul Street London, EC2A 4LQ

Sponsors and Exhibitors Email: [email protected], Website: www.informahealthcare.com Informa Healthcare publishes Gynecological Endocrinology, the official journal of the International Society of Gynecological Endocrinology. For more information and to collect your free sample copies of the journal and of our other journals in obstetrics, gynecology and reproductive medicine please visit us at our Booth. Informa Healthcare incorporates leading medical publishers Martin Dunitz, Taylor and Francis Medical, Parthenon, Marcel Dekker and CRC Press. As the most dynamic publishing group serving the life science and medical markets, it offers a unique range of groundbreaking books and journals from leading authors in the fields of obstetrics, gynecology and reproductive medicine.

16 Karl Storz Gmbh & Co.KG Mittelstrasse 8, D-78532 Tuttlingen Phone: 00497461 7080 - Fax: 00497461 708377 Email: [email protected] Website: www.karlstorz.com KARL STORZ is a renowned manufacturer that is well established in all fields of endo­scopy and can be considered as market leader in rigid endo­scopy. The still family held company was founded in 1945 in Tuttlingen, Germany, and has grown to one with a worldwide presence and 4000 employees. KARL STORZ offers a range of both rigid and flexible endo­scopes for a broad variety of applications. Today’s product range also includes fully integrated concepts for the OR and servicing.

S. Karger AG P.O Box, 4009 Basel, Switzerland Tel: +41 61 306 11 11 Fax: +41 61 306 12 34 Email: [email protected], Website: www.karger.com S. Karger AG is a leading international publisher of medical and scientific journals and books. The Sponsors and Exhibitors privately-owned publishing house combines highly sophisticated production technology with customized services for its authors, editors and readers. Karger’s range in the fields of gynecology and endocrinology includes the scientific journals GYNECOLOGIC AND OBSTETRIC INVESTIGATION (www.karger.com/goi) and HORMONE RESEARCH (www.karger.com/hre), as well as the book series ‘Endocrine Development’ edited by P.E. Mullis and ‘Frontiers of Hormone Research’ edited by A.B. Grossmann. The publications are also accessible online at www.karger.com/gynecology and www.karger.com/endocrinology, with full-text search of articles and many other services.

MDT Medical Development & Technology BV Slibbroek 32 5081 NS Hilvarenbeek The Netherlands Tel: +31-(0)135287149 – Fax: +31-(0)135287148 Email: [email protected] Website: www.mdt.eu MDT is leading in state-of-the Art instruments for ART. Our Follicle Aspiration Sets, Probecovers,Insemination and Embryo Transfer catheters, are in use by a large number of leading fertility centres with superior results.

Medicult Italia Spa Via Luca Giordano, 7/B 50132 FIRENZE Tel: +39 055 571476 - Fax: +39 55 5000889 Email: [email protected] Website: www.medicult.com “MediCult a/s is a leader in delivering leading innovative ART solutions to the benefit of families. Through innovation and product advancements, MediCult aims to help the first dream of every infertile couple come true. It is estimated that a child is born every 8 minutes after conception using a MediCult product. MediCult Denmark has subsidiaries in 8 countries and is listed on the Oslo Stock Exchange (MEC). For further information, please visit www.medicult.com.”

17 Merck Serono Spa Affiliata di Merck KGaA, Darmstadt (Germania) Via Casilina 125, 00176 Roma Tel: +39 06 703841 - Fax: +39 06 70384643 Email: [email protected] Website: www.merckserono.it Merck Serono S.A., headquartered in Geneva (Switzerland), is the division of Merck KGaA that takes care of the development of innovative drugs. The Italian branch Merck Serono S.p.A. has 2 research sites located in Guidonia Montecelio and Ardea, with its production site in Bari, and its management offices in Rome. Thanks to the integration between the commercial activities and the production and research activities, Merck Serono S.p.A. is a strategic hub of excellence for the Group.

Nanopoint, Inc 900 Fort Street Mall, Suite A20 Honolulu, HI 96813 Tel. +001(808) 457-1145 - Fax: 01.808.547.4245 Email: [email protected] Website: www.nanopointimaging.com Nanopoint, Inc. is a privately-held biotechnology company that is advancing the study and treatment of diseases with its live cell imaging solutions. Nanopoint’s cellTRAY® Imaging Systems with integrated microfluidics have broad applications to life science research, drug discovery, and assisted reproductive technology.

Nikon Instruments Spa Via A. Meucci, 59 50041 Calenzano (FI) Tel:+39 055-300950 – fax: +39 055-300995 E-mail : [email protected] Website: www.nikon.it

Pantarhei Bioscience BV PO Box 464, 3700 AL Zeist, The Netherlands Tel: +31 306985028 Fax: +31 306985021 Email: [email protected] Website: www.pantarheibio.com PRB develops new treatment concepts, characterized by proven safety, up to proof-of-concept in human

Sponsors and Exhibitors in Gender-related Medicine (GRM). GRM addresses areas as contraception, infertility, HRT, osteoporosis, oncology, cardiovascular- and auto-immune diseases. PRB currently concentrates on: 1) Androgen Restored Contraception: restoring testosterone levels in women using oral contraception 2) Estetrol (E4): natural human SERM in oral contraception, HRT, breast cancer, osteoporosis 3) ZP: active immunization with zona pellucida antigens for the treatment of ovarian cancer.

18 Schering Plough Corporation Kenilworth, N.J.U.S. Website:www.schering-plough.com, Website: www.schering-plough.it Schering-Plough Corporation (NYSE: SGP) is a global science-based health care company with leading prescription, animal health and consumer health care products. Through internal research and collaborations with partners, Schering-Plough discovers, develops, manufactures and markets advanced drug therapies to meet important medical needs. Our products reach patients and caregivers in more than 140 countries. Following the acquisition in November 2007 of Organon BioSciences (OBS), a Dutch human health (Organon) and animal health (Intervet) company, Schering-Plough had approximately 55,000 colleagues around the world, as of Dec. 31, 2007. With Organon, Schering-Plough acquired that company’s long- standing commitment to the science of fertility. Investments continue in early and later-stage projects that hold out hope for new advances in fertility treatment. The company is based in Kenilworth, N.J., and its Web site is www.schering-plough.com.

Schering Plough Spa

Organon Salute della Donna Sponsors and Exhibitors Via Fratelli Cervi snc Centro Direzionale Milano Due Palazzo Borromini 20090 SEGRATE Tel: +3902-210181 – Fax: +39 02-21018557 Website: www.schering-plough.it/

Solvay Pharmaceuticals Marketing&Licensing AG Hegenheimermattweg 127 4123 Alschwil Switzerland. Tel: +49 511 8570 - Fax: +49 511 8573120 Website: www.Solvay.de Solvay has built an extensive expertise in hormone therapy, most of it relieving menstrual or menopausal symptoms in women. DUPHASTON® (dydrogesterone) is one of the leading progestogens worldwide. It is prescribed for a wide range of gynaecological conditions caused by progesterone deficiency, such as endometriosis, premenstrual syndrome and irregular or absent menstruation, but is also used by women struggling with infertility and habitual abortion. The FEMOSTON® (17beta estradiol/dydrogesterone) family with sequential and continuous combined regimens is an ideal choice for hormone replacement therapy due to the pure side effect profile of dydrogesterone leading to pure estrogenic action relieving menopausal complaints and due to several strengths on the market leading to individualilsation of therapy according to each patient’s need. It is marketed in over 60 countries worldwide. Solvay is worldwide number 2 in hormone replacement therapy. ANDROGEL® provides testosterone therapy to men whose bodies do not make enough testosterone. It is the first testosterone gel approved by the U.S. Food and Drug Administration for therapy in men for conditions associated with absent or low testosterone. With the testosterone gel ANDROGEL® Solvay introduced its first transdermal hormone therapy for men in the United States.For more information visit www.androgel.com

19 Continuous Medical Education

20 UEMS Credits (Europe)

The European Accreditation Council for CME is an official body of the European Association of Medical Specialists (UEMS) being established by the UEMS Management Council meeting in October 1999. The UEMS (European Union of Medical Specialists) has assigned to the 13 th World Congress on Human Reproduction n. 20 Continuous Medical Education European (CME) credits.

These credits are valid for all European Community Countries and are recognized by the American Medical

Association toward the Physician’s Recognition Award (AMA) for Canada and North American Countries. Continuous Medical Education

Certificate Certificates will be distributed at the CME/Certificate Desk on Saturday morning from 10.00 onwards. All information will be available at the CME/Certificates Desk.

Kindly remind that you can collect your Certificate on Saturday morning from 10.00 onwards

Crediti ECM

13th World Congress on Human Reproduction L’accreditamento ECM del 13th World Congress on Human Reproduction è stato richiesto per la categoria del Medico Chirurgo specialista in Ginecologia e Ostetricia, Endocrinologia, Genetica Medica.

Le sessioni scientifiche accreditate sono evidenziate nel Programma Scientifico con il simbolo

Per ottenere i crediti del Programma Educazione Continua in Medicina è obbligatorio: • Frequentare un numero di sessioni giornaliere ECM che coprano l’intera giornata congressuale per l’intera durata del Congresso; • Compilare il Questionario ECM che troverete in distribuzione al Desk ECM della Segreteria Congressuale; • Il Questionario è stato strutturato per sessioni scientifiche. Si prega di rispondere alle domande relative alle sessioni frequentate.

Il Questionario ECM insieme alla scheda di valutazione allegata, dovrà essere riconsegnato al Desk ECM entro la fine del Congresso. La mancata compilazione della Scheda di Valutazione invalida il Questionario. Vi ricordiamo che la verifica del questionario avrà luogo Domenica, 8 marzo 2009 nella sala Venice 1 alla fine dell’ultima sessione. L’attestato ECM verrà inviato agli iscritti dopo aver valutato la verifica dell’apprendimento. Il 13th World Congress on Human Reproduction ha ottenuto 15 (quindici) crediti ECM. Vi ricordiamo che il questionario ECM insieme alla Scheda di Valutazione allegata, dovrà essere riconsegnato al Desk ECM entro la fine del Congresso. La mancata compilazione della Scheda di Valutazione invalida il Questionario.

21 Corso di Aggiornamento su New Opportunities in Gonadotrophins Treatment L’accreditamento ECM del Corso di Aggiornamento su New Opportunuties in Gonadotrophins Treatment è stato richiesto per la categoria del Medico Chirurgo specialista in Ginecologia e Ostetricia, Endocrinologia. Il Corso si terrà il giorno 5 marzo 2009 dalle ore 16.15 alle ore 18.45 in sala Venice 3. Alla fine del Corso avrà luogo la verifica del Questionario. Per ottenere i crediti del Programma Educazione Continua in Medicina è obbligatorio: • Frequentare l’intero Corso • Compilare il Questionario ECM che troverete in distribuzione al Desk ECM della Segreteria Congressuale Il Questionario ECM insieme alla scheda di valutazione allegata, dovrà essere riconsegnato al Desk ECM alla fine del Corso. La mancata compilazione della Scheda di Valutazione invalida il Questionario. L’attestato ECM verrà inviato agli iscritti dopo aver valutato la verifica dell’apprendimento.

Il Corso sarà tenuto in lingua inglese.

Il Corso di Aggiornamento su New Opportunities in Gonadotrophins Treatment ha ottenuto 2 (due) crediti ECM.

Corso di Aggiornamento sul Controllo della Fertilità L’accreditamento ECM del Corso di Aggiornamento sul Controllo della Fertilità è stato richiesto per la categoria del Medico Chirurgo specialista in Ginecologia e Ostetricia, Endocrinologia. Il Corso si terrà il giorno 6 marzo 2009 dalle ore 08.30 alle ore 13.30 in sala Venice 3. Alla fine del Corso avrà luogo la verifica del Questionario. Per ottenere i crediti del Programma Educazione Continua in Medicina è obbligatorio: • Frequentare l’intero Corso; • Compilare il Questionario ECM che troverete in distribuzione al Desk ECM della Segreteria Congressuale. Il Questionario ECM insieme alla scheda di valutazione allegata, dovrà essere riconsegnato al Desk ECM alla fine del Corso. La mancata compilazione della Scheda di Valutazione invalida il Questionario. L’attestato ECM verrà inviato agli iscritti dopo aver valutato la verifica dell’apprendimento.

Il Corso sarà tenuto in lingua italiana.

Il Corso di Aggiornamento sul Controllo della Fertilità ha ottenuto 2 (due) crediti ECM.

ECM Credits for Italian Delegates Continuous Medical Education The ECM accreditation of the 13 th World Congress of Gynecological Endocrinology has been requested for Physicians specialized in Gynecology and Obstetrics, Endocrinology and General Medicine.

The scientific sessions with credits are highlighted on the Scientific Programme with the sign

In order to obtain credits from the Continuous Medical Education Programme the following steps are mandatory: • Attend a number of daily ECM sessions that cover the whole congress day for the entire duration the congress; • Fill in the ECM Questionnaire that you will find at the ECM Desk of the Congress Secretariat; The Questionnaire is structured per scientific session, we kindly ask you to answer the questions related to the sessions you have attended.

The Questionnaire together with the Evaluation Form will have to be handed back to the ECM Desk

22 before the end of the Congress. The Questionnaire has validity only when accompanied by the completed Evaluation Form. Kindly note that at the evaluation of the questionnaire will take place on Sunday March 8th 2009 Hall Venice 1 at the end of the last session.

Kindly remember that the Questionnaire together with the Evaluation Form will have to be handed back to the ECM Desk before the end of the Congress. The Questionnaire has validity only when accompanied by the completed Evaluation Form.

The ECM certificate will be sent to the participants, via post or e-mail, after the evaluation of the answers. Continuous Medical Education The 13th World Congress on Human Reproduction has obtained 15 (fifteen) credits ECM.

Educational Course about the New Opportunities in Gonadotrophins Treatment The ECM accreditation of the Course of Updating about the New Opportunities in Gonadotrophins Treatment has been requested for Physicians specialized in Gynecology and Obstetrics, Endocrinology.

The Course take place on Wednesday March 5th 2009 from 16.15 to 18.45 in Hall Venice 3. At the end of Course will take place the verification of Questionnaire.

In order to obtain the credits of the Continuous Medical Programme the following steps are mandatory: • Attend the whole Course; • Fill in the ECM Questionnaire that you will find at the ECM Desk of the Congress Secretariat.

The Questionnaire ECM together with the Evaluation Form, will have to be handed back to the ECM Desk before the end of the Course. The Questionnaire has validity only when accompanied by the completed Evaluation Form. The ECM certificate will be sent to the participants, via post or email, after evaluation of the answers. The Course about the New Opportunities in Gonadotrophins Treatment will be in English language. The Educational Course about the New Opportunities in Gonadotrophins Treatment has obtained 2 (two) credits ECM.

Educational Course about the Control of Fertility The ECM accreditation of the Course of Updating about the Control of Fertility has been requested for Physicians specialized in Gynecology and Obstetrics, Endocrinology. The course take place on Friday March 6th 2009 from 08.30 to 13.30 in Hall Venice 3. At the end of course will take place the verification of Questionnaire. In order to obtain the credits of the Continuous Medical Education Programme the following steps are mandatory: • Attend the whole course; • Fill in the ECM Questionnaire that you will find at the ECM Desk of the Congress Secretariat.

The Questionnaire ECM together with the Evaluation Form, will have to be handed back to the ECM Desk before the end of the Course. The Questionnaire has validity only when accompanied by the completed Evaluation Form.

The ECM certificate will be sent to the participants, via post or email, after the evaluation of the answers.

The Course will be in Italian language.

The Educational Course about the Control of Fertility has obtained 2 (two) credits ECM.

23 Social Programme for participants (included in the registration fee)

• Opening Ceremony at the Congress Venue Thursday, March 5 th 10.00 • Get-Together Evening at La Fenice Theatre Thursday, March 5 th 19.30 – 22.00 • Venetian Cocktail Poster Session Saturday, March 7 th 17.30 – 19.00 • Closing Ceremony at the Congress Venue Sunday, March 8 13.30

Social Programme for registered accompanying persons (included in the registration fee)

• Opening Ceremony at the Congress Venue Thursday, March 5 th 10.00 • Get -Together Evening at La Fenice Theatre Thursday, March 5 th 19.30 – 22.00 • Half-day Venice city tour • Closing Ceremony at the Congress Venue Sunday, March 8 13.30

For the details on the visit to La Fenice Theatre, please check your invitation card or come to the Social Events Desk for more information. The Social Event Desk is available for any information you might need. Social Programme

24 Social Programme

25 Thursday, March 5th

Programme at-a-glance

Hall Hall Hall Hall Hall Venice 1 Venice 2 Venice 3 Goldoni- Casanova Vivaldi

10.00-10.10 Official Opening and Welcome Speeches

Memorial Speeches 10.10-10.30 In memory of Luigi Mastroianni

Opening Lecture 10.30-11.00 Future trends in reproductive medicine

BAYER SCHERING Plenary Session Round Table Oral Presentations Sponsored Symposium Genetics and stem Complicated New frontiers 11.00-13.00 A fresh look at contraception cells pregnancy and in reproductive delivery medicine

IBSA 14.00-14.30 Round Table Oral Presentations Sponsored Symposium Plenary Lecture Early pregnancy Menopause Fostimon: clinical findings with a new type loss of human FSH Theory and practice of preimplantation genetic screening 14.00-16.00 14.30-16.00

Plenary Session

Endometriosis: from disease to diagnosis

Plenary Session SERONO Round Table Oral Presentations Educational Course Perinatal medicine Imaging technology Basic and clinical 16.15-18.45 New opportunities in reproduction endocrinology

Scientific Programme in gonadotrophins treatment

26 OPENING CEREMONY

Hall Venice 1 Thursday, March 5th, 10.00 - 11.00 am

Narch 5th All participants are invited to join us for the Opening Ceremony.

Official Opening and Welcome Speeches 10.00 – 10.10

by Prof. Joseph G. Schenker Scientific Programme President of the International Academy of Human Reproduction

by Prof. Andrea R. Genazzani President of the Congress

by Prof. Liselotte Mettler Secretary of the International Academy of Human Reproduction

Memorial Speeches 10.10 – 10.30 in memory of Luigi Mastroianni

Prof. Joseph G. Schenker

Prof. Jerome F. Strauss

Prof. Pasquale Patrizio

Opening Lecture 10.30 – 11.00 by Joseph Schenker “Future trends in reproductive medicine”

Chairman: Prof. Enrico Genazzani

27 Thursday, March 5th Hall Venice 1+2

10.00 - 10.10 OFFICIAL OPENING AND WELCOME SPEECHES

Schenker Joseph, Mettler Liselotte, Genazzani Andrea R.

10.10 - 10.30 MEMORIAL SPEECHES IN MEMORY OF LUIGI MASTROIANNI

Schenker Joseph, Strauss Jerome F., Patrizio Pasquale

10.30 - 11.00 OPENING LECTURE

Chairman: Genazzani Enrico

Schenker Joseph - Future trends in reproductive medicine

11.00 - 13.00 SPONSORED SYMPOSIUM – ORGANIZED BY BAYER SCHERING A FRESH LOOK AT CONTRACEPTION

Chairmen: Cronin Maureen, Genazzani Andrea R.

Genazzani Andrea R. - Introduction

Cronin Maureen - Bayer Schering Pharma - Partner in women’s healthcare

Panay Nicholas - Benefits of drsp in a novel 24/4 regimen

Shulman Lee - A new drsp containing OC: Clinical experience in the U.S.

Scientific Programme Deypere Herman - LNG-IUS effective and modern contraception with health benefits

Graziottin Alessandra - Introducing natural estradiol in contraception

14.00 - 16.00 SPONSORED SYMPOSIUM - ORGANIZED BY IBSA FOSTIMON: CLINICAL FINDINGS WITH A NEW TYPE OF HUMAN FSH

Chairmen: Gurgan Timur, Schenker Joseph

Welcome and introduction

Caccia Paolo - Different glycosylation status in different marketed FSH products

Baker Valerie - Fostimon versus follitropin-alpha in IVF patients: clinical outcomes from two randomized, multi-center trials

28 Filicori Marco - Basic and clinical correlates of FSH structure

Ulug Ulun - Comparison of efficacy of rec-FSH and highly purified human-derived FSH in GnRH antagonist cycles for ART

Discussion and conclusion

VISIT TO THE EXHIBITION AREA 16.00 - 16.15

16.15 - 18.45 PLENARY SESSION

PERINATAL MEDICINE Scientific Programme

Chairmen: Daya Salim, Petraglia Felice

Klimek Rudolf - Recurrent abortions in infertility patients

Carp Howard - Anticoagulants in recurrent pregnancy loss

Chedraui Peter - The utility of biochemical markers in the prediction of preeclampsia

Holzgreve Wolfgang - Fetal-maternal cell and DNA traffic now allows for non-invasive prenatal diagnosis and prediction of pre- eclampsia

Graziottin Alessandra - Mother-child’ attachment dynamics in pregnancy and predictors of disruption

29 Thursday, March 5th Hall Venice 3

11.00 - 13.00 PLENARY SESSION GENETICS AND STEM CELLS

Chairmen: Schmutzler Andreas G., Tan Seang Lin

Gianaroli Luca - Chromosomal aneuploidy in human oocytes

Patrizio Pasquale - Gene expression profiles of oocytes and cumulus cells

Simi Paolo - Genetic screening in infertile couples for ART

Veiga Anna - Human embryonic and pluripotent stem cells

Illmensee Karl - Modern embryo biotechnology with applications in ART

14.00 - 14.30 PLENARY LECTURE

Chairmanship: Patrizio Pasquale

Schmutzler Andreas G. - Theory and practice of preimplantation genetic screening

14.30 - 16.00 PLENARY SESSION ENDOMETRIOSIS: FROM DISEASE TO DIAGNOSIS

Chairmen: Colacurci Nicola, Shoham Zeev

Scientific Programme Petraglia Felice - Endometriosis: a pathophysiological perspective for medical treatment

Loverro Giuseppe - Role of estrogen receptors in ovarian endometriosis pathophysiology

Exacoustos Caterina - Sonographic evaluation of pelvic endometriosis

Adamyan Leyla V. - Severe forms of endometriosis contemporary treatment modalities

VISIT TO THE EXHIBITION AREA 16.00 - 16.15

30 16.15 - 18.45 EDUCATIONAL COURSE NEW OPPORTUNITIES IN GONADOTROPHINS TREATMENT Educational Contribution by Serono

Chairmen: Revelli Alberto, Tarlatzis Basil

Genazzani Andrea R. - Welcome and introduction

Borini Andrea - A new algorithm in gonadotrophins treatment

De Placido Giuseppe - From FSH to FSH+LH in sub-optimal ovarian response

Lanzone Antonio -

LH vs HCG in ovulation induction Scientific Programme

Revelli Alberto – Tarlatzis Basil Conclusion

31 Thursday, March 5th Hall Goldoni-Vivaldi

11.00 - 13.00 ROUND TABLE COMPLICATED PREGNANCY AND DELIVERY

Chairmen: De Placido Giuseppe, Loverro Giuseppe

Miozzo Monica - Epigenetic evaluation of fetal-placental unit in normal and growth restricted (IUGR) pregnancies

Kashanian Maryam - A comparison between the incidences of respiratory distress syndrome in preterm infants who were born within 24 hours of dexamethasone being administered to the mother versus those mothers without

Berisavac Milica - Perinatal outcome of monofetal pregnancy after IVF

Mocuta Diana - A statistical analysis of preterm birth’s risk factors

Mannella Paolo - Incidence of cervical-vaginal infections in preterm labor

Chedraui Peter - Induction of labor with vaginal 25 mcg misoprostol in term gestations complicated with preeclampsia

Palumbo Marco - Increased caesarean section: what’s the future?

14.00 - 16.00 ROUND TABLE EARLY PREGNANCY LOSS

Chairmen: Chedraui Peter, Cicinelli Ettore

Diaz Alexandra - Factors affecting the abortion rate after in vitro fertilization

Scientific Programme Tolmacheva Ekaterina - Dose-dependent skewed X-chromosome inactivation in spontaneous abortions with trisomy 16 mosaicism: significance for the search of tentative autosomal trans-acting X-inactivation factor

Rusu Ludmila - Analysis of genetic factors of couples with recurrent spontaneous abortions

Makatsariya Alexander - Pathogenetic prophylaxis of recurrent fetal loss syndrome in patients with thrombophilia

Coccia Maria Elisabetta - The role of sonohysterography in diagnostic management in recurrent pregnancy loss patient

Vaquero Elena - Dynamic evaluation of thyrotrope reserve may predict early maternal thyroid impairment in women affected with unexplained recurrent miscarriage: a case-control study

Lebedev Igor - Epimutations of imprinted genes in first-trimester spontaneous abortions: incidence, mechanisms of formation and significance for estimation of epigenetic risks related with assisted reproductive technologies

32 VISIT TO THE EXHIBITION AREA 16.00 - 16.15

16.15 - 18.45 ROUND TABLE IMAGING TECHNOLOGY IN REPRODUCTION

Chairmen: Angioni Stefano, Exacoustos Caterina

Nikolaou Marinos - Transvaginal-ultrasound guided aspiration of benign ovarian cysts: a retrospective study of 46 cases

Exacoustos Caterina - Septate uterus in infertile patients: histology of septal tissue after hysteroscopic metroplasty and correlation to three-dimensional power Doppler sonography of the septum

Pinto Vincenzo - Scientific Programme Altered uterine contractility pattern in the periovulatory phase of women with chronic endometritis

Papoutsis Dimitris - Endometrial Volume of uterin fundus as a predictor of outcome in IVF: a pilot study

Provansal Magali - Ultrasound monitoring in patients undergoing in vitro fertilization after methotrexate treatment for ectopic pregnancy

Risquez Francisco - Color doppler ultrasound guided oocyte retrieval in women with adnexal varicocities

33 Thursday, March 5th Hall Casanova

11.00 - 13.00 ORAL PRESENTATIONS NEW FRONTIERS IN REPRODUCTIVE MEDICINE

Chairmen: Borini Andrea, Schenker Eran

Groendahl ML, Andersen CY, Bogstad J, Borup R - Effect of maternal age on granulosa cell messenger RNA expression profile

Giannini A, Merlini S, Bucci F, Cubeddu A, Freschi L, Casarosa E, Pluchino N, Cela V, Luisi M, Genazzani AR - Brain-derived neurotrophic factor in endometriosis

Glinkina Z, Kuzmichev L, Bakharev V, Ikonnikov M, Diyakonov S - Study of HLA I and II antigens in ART couples

Yavorovskaya K, Nazarenko TA, Sursalina AV, Perminova SG, Stankovic EB - Characteristics of immune status in infertile women in IVF program positive for thyroid autoantibodies

Monteleone P, Cela V, Simi G, Di Berardino OM, Valentino V, Genazzani AR, Artini PG - Isolation and anti-thyroid antibodies in follicular fluid, granulosa cells and oocytes of euthyroid patients with thyroid autoimmunity undergoing IVF

Coppola G, Bianco C, Peluso SR, Cariati F, Conforti A, Alviggi C, Clarizia R, Mollo A, De Placido G - High intrafollicular concentrations of Benzene are associated with increased basal FSH levels and reduced ovarian outocome in IVF cycles

Hammadeh ME, Hamad MF, Filippos A, Rosenbaum P, Schmidt W - Relationship between oxidative stress of serum, follicular fluid and IVF/ICSI outcome

Aurrekoetxea I, Ruiz del Agua A., Matorras R, Exposito A, Crisol L, Hernandez ML, Ruiz-Sanz JI, Ruiz- Larrea M - Oxidative stress is associated to pregnancy in IVF cycles

Simi G, Monteleone P, Di Berardino OM, Viana G, Valentino V, Cela V, Genazzani AR, Artini PG - DHEA supplementation in poor responders improves follicular microenvironment

Di Berardino OM, Monteleone P, Simi G, Valentino V, Cela V, Genazzani AR, Artini PG - Scientific Programme Basic evidence of hypoxic follicular microenvironment in anovulatory women with polycystic ovaries

Merlini S, Gianni A, Cubeddu A, Bucci F, Russo M, Casarosa E, Pluchino N, Luisi M, Genazzani AR - Brain-derived neurotrophic factors (BDNF) in menstrual blood

Tropea A, Romani F, Loiudice I, Corasaniti C, Orlando MT, Tiberi F, Catino S, Lanzone A, Apa R - The in vitro effect of Proghrelin-derived peptides on purified human luteal cells

14.00 - 16.00 ORAL PRESENTATIONS MENOPAUSE

Chairmen: Brincat Mark, Gambacciani Marco

Cubeddu A, Giannini A, Merlini S, Bucci F, Daino D, Centofanti M, Ninni F, Pluchino N, Genazzani AR - Paroxetine increases brain-derived neurotrophic factor (BDNF) in menopausal women

Bulajic E - How oral probiotics (GR-1/RC-14) recover vaginal ecosystem balance in the early menopause

34 Nacu L - Transdermal estrogen with a levonorgestrel-releasing intrauterine device for climacteric complaints

Povoroznyuk V, Grygoryeva NV, Dzerovych NI, Karasevskaya TV - Effectiveness of two regimens of glucosamine and chondroitin for treatment of pain syndrome in postmenopausal women with knee osteoarthritis

Pelotti D, Frattini G - Menopause and depression

Muscat Baron Y, Brincat M, Galea R - Intervetebral disc height in postmenopausal women with osteoporotic vertebral fractures

Makatsariya A, Bitsadze VO, Baimuradova SM, Akinshina SV - Thrombophilia in pathogenesis of thrombothic complications of hormonal replacement therapy

Abdollahy F, Azadbakht MR, Abhari F, Shabankhani B - Effect of aqueous Glycyrrhza globra extract on menopausal symptoms Scientific Programme Chedraui P, Cuadros-Lopez JL, Amaya-Navarro F, Sabatel-Lopez RM, Nogales-Fernandez F, Perez- Lopez FR - Endometrial findings in postmenopausal women during hormone therapy

Mannella P, Sanchez AM, Giretti MS, Genazzani AR - Estrogen and progestins differently prevent glutamate toxicity in cortical neurons depending on prior hormonal exposure via the induction of neural nitric oxide synthase

Paavonen J, Halmesmaki K, Hurskainen R, Grenman S, Kivela Eija A, Tuppurainen TM, Heiliovaara- Peippo S - Estrogen therapy among menorrhagia patients treated by hysterectomy or levonorgestrel-releasing intrauterine system (LNG-IUS) - a 10-year follow-up study

Diaz B, Llaneza P - Melatonin delayed the reproductive hormonal pattern during the perimenopausal transition

VISIT TO THE EXHIBITION AREA 16.00 - 16.15

16.15 - 18.45 ORAL PRESENTATIONS BASIC AND CLINICAL ENDOCRINOLOGY

Chairmen: Fanchin Renato, Nappi Rossella E.

Manoku N, Kroi E - Hyperprolactinemia and infertility

Tanko O, Samoylova MV - Immune profile patients with hyperprolactinemia

Laisk T, Laanpere M, Haller-Kikkatalo K, Salumets A - The effects of X-chromosome variations and inactivation on ovarian reserve markers

Chaidogiannos K, Patsouras K, Giannaris D, Salamelekis G, Dima K, Kassanos D - Low AMH serum concentration on day 3, what is the meaning

35 Goglia L, Tosi V, Garibaldi S, Baldacci C, Mannella P, Pisaneschi S, Giretti MS, Flamini MY, Sanchez AM, Genazzani AR, Simoncini T - The effects of testosterone and dihydrotestosterone on endothelial nitric oxide synthase activity

Tsigkou A, Reis FM, Luisi S, Roviello F, Silva-Filho AL, Groome NP, Giannos J, Petraglia F - Total inhibin levels are increased in postmenopausal women with ovarian granulosa cell tumor

Romano A, Adriaens M, Kuenen S, Delvoux B, Dunselman G, Evelo C, Groothuis P - Cell and gene specific responses to 17?-estradiol and tamoxifen are determined by co-regulator recruitment to activated estrogen receptor-? Promoter complexes

Buda F - The long term chemotherapy consequences of the reproductive function of young cancer patients

Ilovayskaya I, Zektser VY, Vityazeva II, Goncharov NP, Melnichenko GA - Clinical and hormonal features of hypo- and normogonadotropic amenorrhea

Lissoni S, Baronchelli S, Villa N, Dalprà L - Cytogenetic and molecular study of six women affected by POF: breakpoint analysis and chromosome territories evaluation in interphase nuclei

Park H, Pagan L, Tan O, Demir N, Fadiel A, Mittal K, Naftolin F - Polysialated neural cell adhesion molecule (PSA-nCAM) is expressed by human blood vessel endothelial cells

Xu J, Shen Z, Lin J - Estrogen replacement therapy resumes hypothalamic-pituitary-ovarian axis function in women with weight loss-related amenorrhea Scientific Programme

36 GET-TOGETHER EVENING

La Fenice Theatre Thursday, March 5th, 19.30 – 22.00

Cocktail and Concert

th In honour of our 13 World Congress the famous Fenice Theatre opens its Scientific Programme doors inviting you to a cocktail and a chamber concert.

For details on a seat reservation and time-schedule please see your invitation card.

For safety reasons no entrance can be allowed without the invitation card.

We thank IBSA Institut Biochimique SA for its kind contribution

37 Scientific Programme

38 Friday, March 6th

Programme at-a-glance

Hall Hall Hall Hall Hall Venice 1 Venice 2 Venice 3 Goldoni- Casanova Vivaldi

Plenary Session 08.30-09.00 BAYER SCHERING Special Session Oral Presentations Corso di Rapid signalling of Plenary Lecture Aggiornamento New aspects Sexual and 08.30-10.00 steroid receptors in reproductive psychological Hormonal treatment Controversie, medicine aspects of human of recurrent confronti, condivisioni reproduction miscarriage in contraccezione con estroprogestinici

Plenary Lecture 09.00-10.40 Scientific Programme

PCO’s clinical Teleconference consequences from European 10.10-10.40 birth to senescence Parliament Brussels

The challenges for reproductive medicine in Europe

ISGE Plenary Session BAYER SCHERING Round Table Oral Presentations Symposium Corso di Oncology Aggiornamento Metabolic syndrome Laboratory aspects 11.00-13.00 New horizons in in ART gynecological Novità in endocrinology contraccezione

Plenary Lecture Plenary Lecture Plenary Lecture

Obstetrics and Donor sperm, Life in space Gynecology in the egg and embryos developing world – clinical and psychological aspects 14.30-15.00

Plenary Session Plenary Session Plenary Session Round Table Oral Presentations Sponsored by IMS Endocrinology Cryopreservation and Menopause and Cancer and Ovulation induction 15.10-17.10 in vitro maturation aging: critical review reproduction and factors of the effects of HRT influencing ART outcome

Plenary Session Plenary Session Plenary Session Round Table Oral Presentations

17.30-19.30 Infectious diseases Ovulation induction The menopause Endometriosis Contraception and human and embryo quality transition and beyond reproduction

39 Friday, March 6th Hall Venice 1

08.30 - 10.00 PLENARY SESSION RAPID SIGNALLING OF STEROID RECEPTORS

Chairmen: Mori Takahide, Naftolin Frederick

Simoncini Tommaso - Rapid signalling of estrogen and progesterone receptors to the cytoskeleton

Brosens Jan - Non-genomic signalling of progesterone receptors in the human female reproductive tract

Castanas Elias - Estrogen and testosterone membrane receptor signalling in prostate and breast cancer cells

Harvey Brian - Rapid estrogen signalling in colon, kidney, lung and breast cancer cells

10.10 - 10.40 PLENARY LECTURE

Chairman: Strauss Jerome F.

Lunenfeld Bruno - PCO’s clinical consequences from birth to senescence

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 SYMPOSIUM INTERNATIONAL SOCIETY OF GYNECOLOGICAL ENDOCRINOLOGY (ISGE) NEW HORIZONS IN GYNECOLOGICAL ENDOCRINOLOGY Scientific Programme

Chairmen: Genazzani Alessandro D., Lunenfeld Bruno

Brincat Mark - Hot flushes and the menopause

Naftolin Frederick - HOX gene-regulated remodeling as a mechanism of the pelvic floor

Devoto Luigi - Progesterone receptors and the human preovulatory follicle

Petraglia Felice - New horizons in endometriosis

Kenemans Peter - Tibolone and the breast: lessons from randomized clinical trials

40 14.30 - 15.00 PLENARY LECTURE

Chairman: Schenker Joseph

Sciarra John - Obstetrics and Gynecology in the developing world

15.10 - 17.10 PLENARY SESSION ENDOCRINOLOGY

Chairmen: Devoto Luigi, Simoncini Tommaso

Naftolin Frederick - Scientific Programme Things that my professor never told me about estrogen and the hypothalamus

Luisi Stefano - Ovarian peptides in hypothalamic amenorrhea

Creatsas George - Adolescent Gynecology: towards a better reproductive health

Nappi Rossella E. - Mood and sex in functional hypothalamic amenorrhea (FHA)

Perez-Lopez Faustino - The vitamin D system and the woman’s general health

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

17.30 - 19.30 PLENARY SESSION INFECTIOUS DISEASES AND HUMAN REPRODUCTION

Chairmen: Klimek Rudolf, Vartej Petrache

Schenker Inon - Male circumcision for HIV prevention: from science to large-scale interventions, strengthening men’s sexual and reprodcutive health in Africa

Perino Antonio - HPV and human reproduction

De Seta Francesco - Lower genital tract infections

Ness Roberta B. - Pelvic infections and fertility

Malik Sonia - Genital tubercolosis and fertility

41 Friday, March 6th Hall Venice 2

08.30 - 09.00 PLENARY LECTURE

Chairman: Carp Howard

Daya Salim - Hormonal treatment of recurrent miscarriage

09.00 - 10.40 TELECONFERENCE WITH THE EUROPEAN PARLIAMENT IN BRUSSELS: WORLD CONGRESS FOR FREEDOM OF SCIENTIFIC RESEARCH Session proposed by ESHRE The challenges for reproductive medicine in Europe

Chairmen: Busquin Philippe, Simpson Audrey

Gianaroli Luca - Assisted reproduction in Europe

Sunde Arne - Reproduction and the population crisis

Geraedts Joep - Genetics and reproductive health

de Vroey Paul - Healthy babies and safe treatments

Veiga Anna - Reproductive medicine and stem cells

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

Scientific Programme 11.00 - 13.00 PLENARY SESSION ONCOLOGY

Chairmen: Adamyan Leyla, Creatsas George

Querleu Denis - Vaginal radical trachelectomy with laparoscopic pelvic lymphadenectomy (Dargent operation): results

Morice Philippe - Conservative surgery of ovarian cancer

Gadducci Angiolo - Conservative management of endometrial cancer

Peccatori Fedro - Ovarian function after chemotherapy for breast cancer

Maggino Tiziano - Romagnolo Cesare Population study on frequency and outcome of pregnancy in women affected by neoplasia in Veneto Region (North-East Italy)

42 14.30 - 15.00 PLENARY LECTURE

Chairman: Dor Jehoshua

Kovacs Gabor - Donor sperm, egg and embryos - clinical and psychological aspects

15.10 - 17.10 PLENARY SESSION CRYOPRESERVATION AND IN VITRO MATURATION

Chairmen: Illmense Karl, Polatti Franco

Gurgan Timur - Scientific Programme In vitro maturation of oocytes: patient selection and results

Tan Seang Lin - Recent advances in in-vitro maturation (IVM) for treatment of infertility

Artini Paolo G. - Cryopreservation of oocytes and human embryos by vitrification or slow freezing

Isachenko Evgenia - Ovarian tissue cryopreservation: for reproduction, for therapy or for both?

Dor Jehoshua - ART after autotransplantation of freeze/thawed ovarian tissue

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

17.30 - 19.30 PLENARY SESSION OVULATION INDUCTION AND EMBRYO QUALITY

Chairmen: Baker Valerie, Volpe Annibale

Filicori Marco - Use of HCG during controlled ovarian stimulation

Ubaldi Filippo M. - Influence of stimulation protocols on oocyte nuclear maturity and cytoplasmic maturity

Shoham Zeev - Do we need LH for ovarian stimulation?

Ossipova Agnessa - Non invasive assessment of oocyte competence for clinical use

Devoto Luigi - Luteal phase physiology and its relevance for steroids and human HCG treatment

43 Friday, March 6th Hall Venice 3

08.30 - 10.40 CORSO DI AGGIORNAMENTO CONTROVERSIE, CONFRONTI, CONDIVISIONI IN CONTRACCEZIONE CON ESTROPROGESTINICI Realizzato con il contributo educazionale di Bayer Schering

Chairman: Genazzani Andrea R.

Biglia Nicoletta - Rischio oncologico

Bruni Vincenzina - Tromboembolismo

Fruzzetti Franca - Anamnesi ed esami di laboratorio

Dei Metella - Adolescenti

Arisi Emilio - Pazienti a rischio

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 CORSO DI AGGIORNAMENTO NOVITA’ IN CONTRACCEZIONE Realizzato con il contributo educazionale di Bayer Schering

Chairman: Palumbo Giuseppe Scientific Programme Cianci Antonio - Evoluzione dei progestinici

Fruzzetti Franca - Profilo di un nuovo estroprogestinico

Lello Stefano - Iperandrogenismo e terapia estroprogestinica

Petraglia Felice - Approccio ormonale alla sintomatologia premestruale

14.30 - 15.00 PLENARY LECTURE

Chairman: Benagiano Giuseppe

Schenker Eran - Life in space

44 15.10 - 17.10 PLENARY SESSION Sponsored by the INTERNATIONAL MENOPAUSE SOCIETY MENOPAUSE AND AGING: CRITICAL REVIEW OF THE EFFECTS OF HRT

Chairmen: Siseles Nestor, Sturdee David

Pines Amos - Cardiovascular effects of HRT - an update

Genazzani Andrea R. - Brain effects

Gambacciani Marco - Joint and bone effects

Brincat Marc - Skin and urogenital tissues Scientific Programme

Schneider Hermann P.G. - Effects on breast cancer and other hormone sensitive tumours

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

17.30 - 19.30 PLENARY SESSION THE MENOPAUSE TRANSITION AND BEYOND

Chairmen: Pines Amos, Sciarra John

Cianci Antonio - Premenopausal steroids and quality of life

Siseles Nestor - Contraception in the menopausal transition

Sturdee David - The hot flush: enigma of the menopause

Meier Christoph - Risk factors with different HRT regimens

Birkhaeuser Martin - Quality of life and sexuality

45 Friday, March 6th Hall Goldoni-Vivaldi

08.30 - 10.40 SPECIAL SESSION NEW ASPECTS IN REPRODUCTIVE MEDICINE

Chairmen: Ben Rafael Zion, Cianci Antonio

Colacurci Nicola - The role of relaxin on reproductive variables

Cicinelli Ettore - Chronic endometritis and reproductive disorders

Monteleone Patrizia - The study of perifollicular blood flow in patients undergoing IVF

Polatti Franco - Current strategies in the management of ovarian hyperstimulation

Caserta Donatella - Moscarini Massimo - Oocyte genetic analysis: clinical impact

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 ROUND TABLE METABOLIC SYNDROME

Chairmen: Lanzone Antonio, Perez-Lopez Faustino

Zhao Yun - Clinical features, reproductive endocrine, and metabolic abnormalities of adolescent girls with polycystic ovary syndrome (PCOS)

Virtej Ioana - Polycystic ovary syndrome and associated nonalcoholic fatty liver disease-clinical, metabolic and therapeutic Scientific Programme particularities

Giuliani Albrecht - Polycystic ovary syndrome: metabolic and endocrine aspects

Vujovic Svetlana - Premature ovarian failure and metabolic syndrome

Povoroznyuk Vladyslav - Associations between the metabolic syndrome and bone mineral density in Ukranian women in postmenopausal period

Chedraui Peter - Increased sexual complaints in postmenopausal women with hyperglycemia

15.10 - 17.10 ROUND TABLE CANCER AND REPRODUCTION

Chairmen: Gadducci Angiolo, Morice Philippe

46 Voigt Kristina - Case-control study of breast cancer risk for levonorgestrel-releasing intrauterine devices

Fabbri Raffaella - The issue of ovarian tissue cryopreservation in children with Hodgkin’s lymphoma

Buda Francesco - Update on recent clinical trials of the hormonal suppression with gonadotropin releasing hormone agonists (GNRH) treatment for fertility preservation in cancer females

Cantù Maria Grazia - Gonadic function and reproductive outcome in patients with malignant germ cell tumours

Abakushina Elena - Cryopreservation of ovarian tissue can protect fertility for young patients prior to treatment

Sopracordevole Francesco - Conservative treatment of microinvasive adenocarcinoma of the cervix Scientific Programme Del Pup Lino - How to treat vagin-al atrophy and dispareunia in oncological patients?

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

17.30 - 19.30 ROUND TABLE ENDOMETRIOSIS

Chairmen: Busacca Mauro, Maggino Tiziano

Fasciani Alessandro - Identification of somatostatin receptors in endometrium and lesions of patients affected by endometriosis

Abdullah Nustratuddin - Analysis on vascular endothelial growth factor (VEGF) gene polymorphism in endometriosis

Kogan Evguenija - Molecular markers of proliferation, apoptosis, invasion and neoangiogenesis and their possible role in the pathogenesis of adenomyosis

Tocci Angelo - Endometrial subendometrial myometrium (ESEMy) unit disruption disease: a reasoned proposal for a novel condition affecting fertility

Camara Oumar - Treatment of endometriosis of uterosacral ligament and rectum through the vagina

Coccia Maria Elisabetta - Does controlled ovarian hyperstimulation in women with a past history of endometriosis influence recurrent rate?

Hudelist Gernot - Combination of transvaginal sonography (TVS) and clinical examination (PV) for preoperative diagnosis of deep infiltrating endometriosis (DIE)

Ribeiro Ricardo - Impact of laparoscopic cystectomy on fertility in an infertile population with ovarian endometrioma

47 Friday, March 6th Hall Casanova

08.30 - 10.00 ORAL PRESENTATIONS SEXUAL AND PSYCHOLOGICAL ASPECTS OF HUMAN REPRODUCTION

Chairmen: Lachwosky Michèle, Valentino Valeria

Kokabi R, Anvar M, Meshkibaf MH - Study of psychiatric disturbance in infertile women

Kristesashvili J, Chipashvili M, Jorbenadze M, Tskhovrebashvili L - Sexual development disorders (SDD) in patients with primary amenorrhea

Righetti PL, Girlanda F, Romagnolo C, Panizzo F, Maggino T - Psychological aspect of IVG: report of an empirical search

Esterle M - Judging the acceptability of sexual intercourse among persons with learning disabilities: French Laypeople’s Viewpoint

Radwan D, Ramy H, Elsayed M, Elmissiry A, Moussa Kh., Mansour M, Khalil A - Comorbidity between infertility and depression and anxiety disorders in a sample of Egyptian women: effect on treatment outcome and quality of life

Steyn P, De Jong G - Attitude of parents towards puberty and sexuality in cognitive impaired children

Taavoni S, Aahadie M, Ghanjie T, Hoseinie F - Comparison of anxiety in primigravidas and multigravidas with history of fetalor neonatal death (MASHAD, 2006)

Heurckmans N, Verte D, Ponjaert-Kristoffersen I - Research on attitudes of fathers, mothers and students towards donor insemination

Lykeridou K, Gourounti K, Sarantaki A, Deltsidou A, Vaslamatzis G - The impact of social class on infertility related stress and coping strategies

Gourounti K, Anagnostopoulos F, Vaslamatzis G - Predictors of infertility related distress: presentation of a predicted model Scientific Programme

Fadaei S, Jonighorbany M - Study of the effect of cognitive behavioral counseling on body image alterations in women undergone mastectomy

Wallwiener M, Seeger H, Mueck AO, Bitzer J, Wallwiener C - The sexual life of German Medical Students: investigation of the prevalence of sexual dysfunction and the impact of contraception

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

48 11.00 - 13.00 ORAL PRESENTATIONS LABORATORY ASPECTS IN ART

Chairmen: Isachenko Evgenia, Ubaldi Filippo M.

Cassuto NG, Bouret D, Plouchart JM, Barak Y - How to choose the best spermatozoon for ICSI

Gonzalez-Ferreira S, Estela-Burriel P, Espejo-Catena MR, Cuenca-Torres M, Guerrero-Espejo A - Influence of the spermatozoids morphology in the sperm capaciting

Hammadeh ME, Muller CE, Rosenbaum P, Schmidt W - The effect of freezing method on the acrosome, chromatin integrity and DNA fragmentation of human spermatozoa

Tug N, Sandal S, Ozelgun B, Aktas G, Yilmaz B, Kamil Z - Correlation of spermiogram profiles with DNA damage in sperm cells of infertile men: a comet assay study Scientific Programme

Ugras Murat Y, Karabulut AB, Soylemez H, Sogutlu M - Reseveratrol prevents spermatogenetic damage in rats exposed to cigarette smoke

Del Rio F, Brassesco A, Gomez M, Brassesco M - Comparison between PVP clinical grade and spermslowTM in sperm selection for ICSI

Cairo Doncos O, Prats L, Rodriguez M, Rovira S, Gomez M, Brassesco A, Del Rio F, Brassesco M - Predictive value of pregnancy after blastocysts obtaining from supernumerary-cultured embryos

Chan Melinda LH, Prasath EB, Loh SF - Influence of early cleavage checks on embryo selection

Steele M, Kopakaki A, Papanicou C, Sciorio R, Pickering SJ, Thong KJ - Embryo development and implantation potential in Cook and Medicult sequential culture media

Keck G, Elfenkamper A, Gneist N, Trinkaus I, Gouma E, Hanseroth K, Leuchten B, Thieme B, Distler W - Rating of zygotes from ART cycles with poor fertilization rate and successful pregnancy

Dasuki D, Fauzia I, Haryadi D - Assisted hatching of less than 1/4 compared to more than 1/4 of zona pellucida of mice embryos (Swiss Albino) cultured in vitro

Mohamadi M, Movahedin M, Koruji M - The effect of co-culture with sertoli and STO cells on spermatogonial stem cell colonization

Selvaraj P, Selvaraj K - Embryo survival rates in frozen-thawed cycles - A comparison between in-house and commercial media

Han HD, Lim CK, Hyon N, Lee JH, Hong M - The effect of low dose hypoxanthine in FSH and FBS supplemented medium on mouse oocyte in vitro maturation (MII development)

15.10 - 17.10 ORAL PRESENTATIONS OVULATION INDUCTION AND FACTORS INFLUENCING ART OUTCOME

Chairmen: Filicori Marco, Ossipova Agnessa

Spadoni V, Sagnella F, Moro F, Martinez D, Stifani F, Morciano A, Orlando MT, Gangale MF, Tropea A, Lanzone A, Apa R - Is FSH day3 a reliable marker of ovarian response?

49 Palumbo Angela, Rodriguez A, Garcia R, Iaconianni L, Hernandez J Prospective evaluation of automated follicle monitoring in 58 in vitro fertilization cycles: follicular volume as a new indicator of oocyte maturity

Mehrzad MM, Pourali E, Ayatollahi H - The effect of oral corticosteroid on folliculogenesis of the infertile women under 35 years old undergoing ICSI cycles

Mancini F, Colomé C, Coroloeu B, Rodrigo C, Tur R, Rodriguez I, Barri PN - The clomiphene citrate challenge test for the prediction of response and pregnancy in patients undergoing in- vitro fertilization

Coppola M, Alviggi C, Fabozzi F, Garolla A, Bianco C, Strina I, Peluso S, Foresta C, De Placido G - A common FSH receptor polymorphism is associated with ovarian hypo-response to GnRH-a long protocol in normogonadotrophic women undergoing ovarian stimulation with r-hFSH

Suh BY, Grewal JK - The magnitude of midcycle LH surge as a determinant of midluteal phase progesterone concentration

Romeu M, Peinado I, Torres P, Garcia G, Montanana V, Cabo A, Monzo A, Romeu A - Coasting as a preventive method for ovarian hyperstimulation syndrome in IVF cycles: description and results

Drakakis P, Pafilis I, Loutradis D, Vomvolaki E, Anagnostou E, Antsaklis A - The effect of age on IVF outcome in 800 hundred Mediterranean infertile couples

Goudakou M, Karkanaki A, Kalogiannidis I, Prapas I, Prapas N - Body mass index: is it a significant factor for the success of IVF?

Pinto A, Teixeira L, Figuieredo H, Pires I, Pereira ML, Silva Carvalho JL - Influence of female cigarette smoking in some IVF parameters

Aflatoonian A, Ghandi S, Tabibnejad N - Comparison of coasting with cabergoline administration for prevention of early severe OHSS in ART cycles

Wong VV, Hughes C, Mocanu E - Only two available twins are still a concern, particularly in IVF patients!

Zhao Y, Garcia J, Kolp L, Rodriguez A, Cheadle C, Vlahos NF - Impact of luteal phase support on the gene expression profiles of extracellular matrix and adhesion molecules in human endometrium after controlled ovarian hyperstimulation in the window of implantation Scientific Programme Fisch J, Sher G, Keskintepe L - Optimizing individual embryo transfer outcome: should we transfer one or two, on day 3 or day 5?

Hendarto H, Moeloek FA, Prabowo P - The profile of TNF-alpha, GDF-9 and hyaluronan as a marker of folliculogenesis disturbance in infertile patients with endometriosis

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

50 17.30 - 19.30 ORAL PRESENTATIONS CONTRACEPTION

Chairmen: Bruni Vincenzina, Fruzzetti Franca

Marr J, Bachmann G, Kunz M - Contraceptive efficacy of drospirenone 3mg/ethinylestradiol 20 mcg 24/4: pooled analysis of clinical studies

Pop T, Craiut D, Herczegh R, Mocuta D, Lacziko S, Toma M - Sexual appetite is not obviously influenced by COC

Shimizu Y, Takeuchi T, Miziguchi K, Kyo S - Dienogest, a syntehtic progestin, has a direct antiproliferative effect on human endometrial epithelial cells via suppression of cyclin D1 gene expression

Grigoryan O, Klinishkova EV, Andreeva EN - Influence contraceptive patch “EVRA” of anthropometric measures: carbohydrate, lipid metabolism and hemostatic variables in late reproductive-age women with type 1 diabetes Scientific Programme

Klynishkova E, Grigoryan OG, Andreeva EN - Nuvaring® use and association with carbohydrate metabolism and diabetes mellitus type 1 in late reproductive-age women

Radowicki S, Jarecki R, Kozlowska-Boszko B - Social-demographic characteristics and compliance with the dosing scheme of low-dose combined oral contraceptives among 11.397 women in Poland

Maia H Jr., Casoy J, Athayde C, Coutinho EM - Effect of Omega 3 on breakthrough bleeding during a continuous regimen of oral contraceptive use

Celik O, Hascalik S, Ugras MY, Karakas MH, Aydin EN, Abbasov T - The use of intrauterine embedded magnetic rods for contraception: effects on rat uterine histology and human spermatozoa

Grigore M, Cojocaru C, Mares A - Therapeutic use of LNS-IUS for menorrhagia

Kashanian M, Fekrat M - Evaluation of the hyperlipidemia and hyperglycemia in progesterone only pill (pop) users

Halmesmaki K, Heliovaara-Peippo S, Oksjoki R, Kaaja R, Grenman S, Kivela A, Tomas E, Tuppurainen M, Hurskainen R, Paavonen J - The effect of hysterectomy or levonorgestrel-releasing intrauterine system on cardiovascular disease risk factors in menorrhagia patients - a ten-year follow up of a randomised study

51 Scientific Programme

52 Saturday, March 7th

Programme at-a-glance

Hall Hall Hall Hall Hall Venice 1 Venice 2 Venice 3 Goldoni- Casanova Vivaldi

Plenary Session Special Session Plenary Session Special Session Portuguese Society of Ovarian aging Endometriosis: Women’s well being in Sexual medicine: Reproductive and ovarian tissue surgical and the focus: the role of impact on Medicine preservation integrated therapies contraception gynecological Symposium 08.30-10.00 practice Infertility in Portugal:

epidemiology, laws Scientific Programme and research

Plenary Lecture Plenary Lecture PANTARHEI Sponsored Lecture ART results in USA Adenomyosis: past, 10.10-10.40 and Europe present and future The estrogen agonistic/antagonistic properties of Estetrol

Plenary Session Plenary Session BAYER SCHERING Round Table Oral Sponsored Presentations Polycystic Ovary Diagnostic and Symposium The assisted 11.00-13.00 Syndrome surgical problems in reproduction Infectious diseases and other infertility Young at heart laboratory of the reproductive hyperandrogenisms techniques tract

Plenary Lecture Plenary Lecture CRYO-SAVE Sponsored Lecture Women-centered Laparoscopic healthcare on line: myomectomy still Cord blood benefits for get connected more successful regenerative medicine than non-surgical and obstetrics approaches 14.30-15.00

Plenary Session Plenary Session SIERR Oral Oral Symposium Presentations Presentations Evolution Endoscopy and of Assisted robotic surgery Human oocytes Pregnancy: Polycystic ovary 15.10-17.10 Reproductive update cryopreservation: is from embryo syndrome Techniques since vitrification the ultimate implantation to 1978: 30 years solution? delivery since the first test tube baby

17.30-19.00 Poster Session

53 Saturday, March 7th Hall Venice 1

08.30 - 10.00 PLENARY SESSION OVARIAN AGING AND OVARIAN TISSUE PRESERVATION

Chairmen: Artini Paolo G., Ferraretti Anna Pia

Tarlatzis Basil - Diagnosis and treatment of diminished ovarian reserve in an IVF setting

Fanchin Renato - AMH: still useful to assess the ovarian follicle status and responsiveness to stimulation in 2009?

Volpe Annibale - Markers of ovarian ageing

Cittadini Ettore - A new strategy of fertility preservation combining ovarian tissue cryobanking with retrieval of immature oocytes followed by IVM and vitrification

10.10 - 10.40 PLENARY LECTURE

Chairman: Cittadini Ettore

Ferraretti Anna Pia - ART results in USA and Europe

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 Scientific Programme PLENARY SESSION POLYCYSTIC OVARY SYNDROME AND OTHER HYPERANDROGENISMS

Chairmen: Frydman Réné, Scarselli Gian Franco

Strauss Jerome F. - Molecular mechanisms underlying the phenotypes of PCOS

Mori Takahide - Androgenic spectrum hypothesis of polycystic ovarian morphology

Genazzani Alessandro D. - Estrogen-progestin treatment in hyperandrogenic women

Ben-Rafael Zion - Polycystic ovarian syndrome (PCOS) in women in their forties

54 Fulghesu Anna Maria - Metabolic assessment in young PCOS. New electronic method for the evaluation and the follow-up

14.30 - 15.00 PLENARY LECTURE

Chairman: Coutinho Elsimar

Kenemans Peter - Women-centered healthcare on line: get connected

15.10 - 17.10 PLENARY SESSION EVOLUTION OF ASSISTED REPRODUCTIVE TECHNIQUES SINCE 1978: 30 YEARS SINCE THE FIRST TEST TUBE BABY Scientific Programme

Chairmen: Buhler Klaus, Kovacs Gabor

Frydman Réné - Is there a place for natural cycle in IVF?

Soderstrom-Anttila Viveca - Single versus two or more embryo transfer

Ebner Thomas - Practical application of choosing the best embryo

Garcia Velasco Juan A. - How to avoid OHSS

Diedrich Klaus - Ovarian stimulation and risk of cancer

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

55 Saturday, March 7th Hall Venice 2

08.30 - 10.00 SPECIAL SESSION ENDOMETRIOSIS: SURGICAL AND INTEGRATED THERAPIES

Chairmen: Cela Vito, Gomel Victor

Angioni Stefano - Management of pain recurrence and infertility after surgery for deep infiltrating endometriosis

Zullo Fulvio - Palomba Stefano Infertility treatments in patients older than 35 years with peritoneal factor (a randomized controlled trial)

Scarselli Gian Franco - Integrated approach of endoscopy and ART in infertile patients with endometriosis

Busacca Mauro - Laparoscopic treatment of endometriosis and ovarian reserve

10.10 - 10.40 PLENARY LECTURE

Chairman: Kurjak Asim

Benagiano Giuseppe - Adenomyosis: past, present and future

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 PLENARY SESSION DIAGNOSTIC AND SURGICAL PROBLEMS IN INFERTILITY Scientific Programme

Chairmen: Mettler Liselotte, Zullo Fulvio

Gomel Victor - Laparoscopy and infertility

Strandell Annika - Patients with hydrosalpinx

Mencaglia Luca - Bipolar resectoscope: the future perspective of hysteroscopic surgery

Kurjak Asim - Recent advances in ultrasonic assessment of infertility

Exacoustos Caterina - A new method to evaluate tubal patency: transvaginal hystero-salpingo-contrast-sonography and three- dimensional Coded Contrast Imaging

56 14.30 - 15.00 PLENARY LECTURE

Chairman: Fedele Luigi

Mettler Liselotte - Laparoscopic myomectomy still more successful than non-surgical approaches

15.10 - 17.10 PLENARY SESSION ENDOSCOPY AND ROBOTIC SURGERY UPDATE

Chairmen: Mencaglia Luca, Strandell Annika

Litta P. - Reproductive outcome following hysteroscopic myomectomy Scientific Programme

Fedele Luigi - Obstructive Mullerian malformations

Keckstein J. - Adenomyosis and infertility: the endoscopic approach

Cela Vito - Robotic hysterectomy: techniques and tricks

Mayerhofer K. - Laparoscopic ovarian tissue harvesting for cryopreservation - an effective and safe procedure for fertility preservation

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

57 Saturday, March 7th Hall Venice 3

08.30 - 10.00 PLENARY SESSION WOMEN’S WELL BEING IN THE FOCUS: THE ROLE OF CONTRACEPTION

Chairmen: Birkhaeuser Martin, Fulghesu Anna Maria

Coutinho Elsimar M. - Benefits of menstruation suppression

Bruni Vincenzina - Oral contraceptives in adolescence

Pluchino Nicola - Neuroendocrine effects of chlormadinone acetate

Zahradnik Hans P. - Non contraceptive benefits of modern OC’s: CMA+EE in the management of dysmenorrhea

10.10 - 10.40 SPONSORED LECTURE - ORGANIZED BY PANTARHEI BIOSCIENCE

Chairman: Kenemans Peter

Coelingh Bennink Herjan J.T. - The estrogen agonistic/antagonistic properties of Estetrol

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 SPONSORED SYMPOSIUM - ORGANIZED BY BAYER SCHERING YOUNG AT HEART Scientific Programme Chairman: Birkhaeuser Martin

Mikkola Tomi - HRT: recent insight

Collins Peter - Managing a woman’s cardiovascular risk: a gynaecologists’ guide

Rosano Giuseppe - Menopausal HT: Cardiovascular aspects

Simoncini Tommaso - Breast tissue: effects of drospirenone

58 14.30 - 15.00 SPONSORED LECTURE – ORGANIZED BY CRYO-SAVE

Chairman: Holzgreve Wolfgang

McGuckin - Cord blood benefits for regenerative medicine and obstetrics

15.10 - 17.10 SYMPOSIUM ITALIAN SOCIETY OF EMBRIOLOGY, REPRODUCTION AND RESEARCH (SIERR) HUMAN OOCYTES CRYOPRESERVATION: IS VITRIFICATION THE ULTIMATE SOLUTION?

Chairmen: De Santis Lucia, Gualtieri Roberto

Parmegiani Ludovico - Potential, limits and safety of oocyte cryopreservation Scientific Programme Tatone Carla - Oocyte aging and cryopreservation: an insight from the mouse model

Stuppia Liborio - Alterations of mRNA storage in human cryopreserved oocytes as evidenced by expression profiling

Nottola Stefania - Ultrastructural markers of quality in human vitrified oocytes

Vento Marilena - SIERR multicenter study on oocytes vitrification: troubleshooting and results

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

59 Saturday, March 7th Hall Goldoni-Vivaldi

08.30 - 10.00 SPECIAL SESSION SEXUAL MEDICINE: IMPACT ON GYNECOLOGICAL PRACTICE

Chairmen: Bitzer Johannes, Perino Antonio

Nappi Rossella E. - Hypoactive sexual desire disorder (HSDD): a new entry in gynecological practice

Lachowsky Michèle - How to talk sexuality with our old and older patients

Paarlberg Marieke K. - Sexual assault: impact on gynaecological practice

Valentino Valeria - Impact of infertility on sexual function

Graziottin Alessandra - Iatrogenic etiology of female sexual dysfunction: prevention and treatment

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 ROUND TABLE THE ASSISTED REPRODUCTION LABORATORY TECHNIQUES

Chairmen: Ebner Thomas, Soderstrom-Antilla Viveca

Salehnia Mojdeh - The expression of genes related to apoptosis in cultures of follicles derived from vitrified and non-vitrified ovaries

Scientific Programme Coticchio Giovanni - Maturation stage and culture conditions influence meiotic progression and splindle configuration in human oocytes matured in vitro

Kokkali Georgia - PGD for gene defects in blastocyst stage

Eapen Abey - Should we “assist” hatching for embryos - A restrospective analysis of assisted hatching procedure

Elfenkaemper Andrea - Development potential of fertilized oocytes in the ART - a comparison of two scores

Hammadeh M.E. - The effect of freezing method on the acrosome, chromatin integrity and DNA fragmentation of human spermatozoa

Promponas Emmanouel - Preimplantation factor (PIF*): non-invasive biomarker for embryo selection in IVF

60 Haryadi Dwi - Ovum in vitro maturation and ovarian stimulation at dr Sardjito General Hospital (Long GnRHa, Antagonist, and simple stimulation)

15.10 - 17.10 ORAL PRESENTATIONS PREGNANCY: FROM EMBRYO IMPLANTATION TO DELIVERY

Chairmen: Benedetto Chiara, Luisi Stefano

Moschandreou D, Keramitsoglou T, Ramu S, Stamatkin CW, Farmakidis G, Varla-Leftherioti M, Barnea ER - Circulating levels of preimplantation factor (PIF*) during pregnancy

Gjerris AC, Loft A, Pinborg A, Tabor A, Christiansen M - Low levels of PAPP-A in first trimester of pregnancies conceived after ART and the risk of adverse obstetric outcome

Vaquero E, Lazzarin N, Bertonotti E, Di Giovanni A, Exacoustos C, Pasqualetti P - Scientific Programme Combined fibrinolytic defects and recurrent miscarriage

Luchi C, Schifano M, Nanini C, Di Cianni G, Lencioni C, Genazzani AR - Can nuchal translucency thickness in the first trimester predict GDM onset during pregnancy?

Vityazeva I, Zolotukhina TV, Miroshnikova IV, Ilovayskaya IA - IVF and first-trimester ultrasound and biochemical markers of aneuploidy

Iliescu D, Novac M, Cernea N, Novac L, Cornitescu Fl., Tudorache S, Comanescu A, Capitanescu R, Adam G - Trophoblastic thickness related to gestational age as marker in early pregnancy evolution

Marrichereda V, Perminova T - Biophisical markers of preeclampsia

Cetkovic A, Popovic V, Miljic D, Gojnic M, Djurovic M, Pekic S, Radlovic P, Cvetkovic M - Kisspeptin in pregnancies with pregestational diabetes mellitus as a potential marker of placental dysfunction

Pisaneschi S, Sanchez AM, Garibaldi S, Goglia L, Tosi V, Begliuomini S, Genazzani AR, Coceani F, Simoncini T - Combined functional and molecular analysis of endothelial cells from umbilical vessels of fetuses with normal or restricted intrauterine growth

Grati FR, Sanna E, Manganini M, Pecoraro D, Maggi F, Simoni G - Amniotic fluid mesenchymal stem cells isolation, characterization and cryopreservation

Nasehy L, Ghafarnejad M, Ansarian H, Bahmanabadi A - Comparing a new formula with clinical and Johnson & Toshach’s in accuracy of fetal weight estimation

Hoxhaj O, Bajraktari D, Bare T - The risk of perinatal deaths in fetal growth restriction pregnancies due to preeclampsia

VISIT TO THE EXHIBITION AREA 17.10 - 17.30

61 Saturday, March 7th Hall Casanova

08.30 - 10.00 SYMPOSIUM PORTUGUESE SOCIETY OF REPRODUCTIVE MEDICINE INFERTILITY IN PORTUGAL: EPIDEMIOLOGY, LAWS AND RESEARCH

Chairmen: Gonçalves Joaquim, Torgal Isabel

Silva Carvalho Joao Luis - Characterization of infertility in Portugal from knowledge and attitudes to behaviours and practices

Calhaz Jorge - ART legislation and regulamentatory aspects in Portugal

Santos Jorge - Bariatric surgery and reproductive life

Almeida Vasco - PGD in paramilodoisis

Silva Vladimiro - Health economics and IVF

Plancha Carlos - Cell Biology of oocyte quality

Almeida Henrique - Follicular cells and fluids to access oocyte quality

VISIT TO THE EXHIBITION AREA 10.40 - 11.00

11.00 - 13.00 ORAL PRESENTATIONS INFECTIOUS DISEASES OF THE REPRODUCTIVE TRACT Scientific Programme

Chairmen: Malik Sonia, Ness Roberta B.

Rubbino G, Iemmola A, Caldaci L, Cacciotore A, Raciti D, Merlo L, Palumbo MA - Microbiological screening and infertility

Schillaci R, Giovannelli L, Bellavia C, Natale E, Mangione D, Ruvolo G, Ammatuna P, Perino A - Human papilloma virus association with outcome of in vitro fertilization (IVF): a prospective study

Kokab A, Jennings R, Cross N, Eley A, Pacey A - Physiological levels of seminal gamma interferon induce persistent Chlamydia trachomatis, leading to male infertility

Utkin E, Kulavsky VA - Rehabilitation of reproductive function at the patients with pelvic inflammatory diseases

Milivojevic M - Biomarkers in the prediction of microbial invasion of the uterine cavity

62 Golshani M, Eslami G, Mohammadzadeh G, Taheri S, Suleimani Rahbar AA, Fallah F, Goudarzi H - Semen quality in asymptomatic Iranian infertile men: using Multiplex PCR and Standard Culture methods

Bostan A, Demeestere I, Vanderwinden JM, Devreker F, Englert Y - Nucleoside analog Stavudine depletes mitochondrial DNA without organelle loss in mouse oocytes

Shurshalina AV, Sukhikh GT, Kogan EA, Ezhova LS - CD138 in endometrium: inflammation and receptivity

Cicinelli E, Colafiglio G, Pastore A, Mastrolia S, Fucci AM, Tortorella C, Sciorsci R, Viggiano L - Vascular endothelial growth factor expression in the endometrium of women affected by chronic endometritis

Pelotti D, Frattini G - Dyspermia and infertility and nanobacteria

Uzhegova Z, Grigoryan OG, Andreeva EN - The comparative analysis of a pathology of a cervix of a uterus at endocrine diseases

15.10 - 17.10 Scientific Programme ORAL PRESENTATIONS POLYCYSTIC OVARY SYNDROME

Chairmen: Dei Metella, Palomba Stefano

Navali N - Polycystic ovaries and type 2 diabetes mellitus

Ota H, Goto T, Yoshioka T, Oyama N - Successful pregnancies treated with pioglitazone in infertile patients with polycystic ovary syndrome

Baek K-H, Kim MS, Kim YS, Gu BH, Choi BC, Song S - Proteome analysis of human follicular fluid fromm polycystic ovary syndrome patients

Pelotti D, Frattini G - Polycystic ovary syndrome

Kim JL, Choi YM, Ku SY, Choung SH, Hwang KR, Yoon SH, Lee GH, Moon SY - Estrogen receptor beta gene +1730 G/A polymorphism in women with polycystic ovary syndrome

Peressini L, Bruni V, Dei M, Nannini S, Driul L, Bertozzi S, Londero A, Marchesoni D - Polycystic ovary syndrome: a comparison between classifications and endocrine patterns

Suhartono SH, Sulistiono B, Triyani, Purnomosari D, Hakimi HM, Mubarika S, Temple Smith P - The microsatellite polymorphism (tttta)n in promoter of the CYP11a gene in Java women with Polycystic Ovary Syndrome

Radulovic A, Boagavac M - The policystic ovary syndrome: obesity and hormonal changes

Zhu M, Li X, Lin J - Mathematical relationship features of insulin and testosterone in Chinese woman with polycystic ovary syndrome

Ancuta E, Anghelache-Lupascu I, Anton E, Ancuta C - Polycystic ovary syndrome and metformin therapy: focus on pregnancy outcomes

Ajina M, Chaouach N, Zaouali M, Loussaief W, Ibala S, Memmi A, Tabka Z, Saad A - Analyze statu of low sex hormone-binding globulin in obeses patients with polycystic ovary syndrome (PCOS)

63 Tubic-Pavlovic A, Stefanovic M, Crnogorac Z, Radovic-Janosevic D - Induction ovulation by Metformin in PCO sy patients

Jirge PR - Ovulation induction strategies in PCOS – an Indian scenario

VISIT TO THE EXHIBITION AREA 17.10 - 17.30 Scientific Programme

64 Saturday, March 7th Exhibition Area Venetian Foyer 17.30 - 19.00 POSTER SESSION AND VENETIAN COCKTAIL

POSTER SESSION with VENETIAN COCKTAIL

Exhibition Area, Venetian Foyer Saturday, March 7th, 17,30 – 19,00 Scientific Programme

65 Scientific Programme

66 Scientific Programme

67 Sunday, March 8th

Programme at-a-glance

Hall Hall Hall Hall Hall Venice 1 Venice 2 Venice 3 Goldoni- Casanova Vivaldi

Plenary Session ISPOG Oral Presentations Oral Presentations Symposium ART: the importance of National and Socio-environmental Endoscopy and 08.30-10.30 European Registries Glimpses of aspects of human other surgical psychosomatic reproduction techniques in obstetrics and reproductive gynaecology medicine

Special Session in Italian

11.00-13.30 Aspetti etici della riproduzione umana: dalla contraccezione alla procreazione medicalmente assistita

13.30-13.45 Closing Ceremony and Poster Awards Scientific Programme

68 Sunday, March 8th Hall Venice 1+2

08.30 - 10.30 PLENARY SESSION ART: THE IMPORTANCE OF NATIONAL AND EUROPEAN REGISTRIES

Chairmen: Diedrich Klaus, Gianaroli Luca

Gallo F. - New European tissue directives on reproductive cells: the role of the National ART Registries

Buehler Klaus - 25 years of the German DIR Registry

Scaravelli Giulia - The Italian National ART Register Scientific Programme Hernandez Juana - ART Spanish Registry

Frydman Réné - The French National Registry

VISIT TO THE EXHIBITION AREA 10.30 - 11.00

11.00 - 13.30 SPECIAL SESSION IN ITALIAN ASPETTI ETICI DELLA RIPRODUZIONE UMANA: DALLA CONTRACCEZIONE ALLA PROCREAZIONE MEDICALMENTE ASSISTITA

Chairmen: Cicciarella Raffaele, Genazzani Andrea R., Palumbo Giuseppe

Reichlin M. - Discussione

Mordaci R. - Discussione

Gianaroli L. - Discussione

Nappi C. - Discussione

Busnelli F. - Discussione

Cannizzaro D.C. - Discussione

69 Sunday, March 8th Hall Venice 3

08.30 - 10.30 SYMPOSIUM INTERNATIONAL SOCIETY OF PSYCHOSOMATIC OBSTETRICS AND GYNECOLOGY (ISPOG) GLIMPSES OF PSYCHOSOMATIC OBSTETRICS AND GYNAECOLOGY

Chairmen: Facchinetti Fabio, Wijma Klaas

Damonte Khoury Carlos - Informed consent and difficulties in Ob/Gyn: patient relationship

Wijma Klaas - When labour becomes a disaster: post-traumatic stress disorder after childbirth

Bitzer Johannes - Patients with personality disorders in obstetrics and gynecology

Kentenich Heribert - To treat childless HIV-infected couples-medical, psychological and ethical implications

Benedetto Chiara - Caesarean section on maternal request: what type of counselling?

VISIT TO THE EXHIBITION AREA 10.30 - 11.00 Scientific Programme

70 Sunday, March 8th Hall Goldoni-Vivaldi

08.30 - 10.30 ORAL PRESENTATIONS SOCIO-ENVIRONMENTAL ASPECTS OF HUMAN REPRODUCTION

Chairmen: Luchi Carlo, Monteleone Patrizia

Turp AB - Lunar phase and menstruation

Londero AP, Bertozzi S, Messina G, Fruscalzo A, Peressini L, Driul L, Furlan R, Marchesoni D - Influence of moon features, meteorologic conditions and festivities on conceiving: a retrospective study

Tomic V, Tomic J, Kuna K, Zigmundovac-Klaic D - Seasonality pattern in IVF results, is it really important?

Behruzi R, Hatem M, Goulet L, Fraser W, Li M, Misago C - Scientific Programme Where are the Japanese in the humanization of childbirth?

Khalili MA, Agha-Rahimi A, Tabibnejad N, Sharegh L - Follow up of infertile patients after failed ART cycles in Iran

Hafezi AA, Jouybary L, Sanagoo A - The report of a traditional therapeutic method for females infertility: folk medicine among the people in Ayat Mahalle Village_Qaemshahr (Mazandaran)

Wiweko B, Soebijanto S, Hestiantoro A, Siti N, Tarmizi M, Natadisastra K, Sang S, Arifianto F, Mansyur E - Factors influencing the survival of in vitro fertilization

Giacchi E, Saporosi A, Castellucci P, Di Donna V, Mancini A, Pontecorvi A, Marana M - Role of natural methods of fertility regulation in preventing infertility

Akram O, Faiz Rashid S, Standing H, Mahmood I - Poor sexual and reproductive health of rural women and access to service in Bangladesh

Simonet F, Wilkins R, Heaman M, Smylie J, Labranche E, Minich K, Martens P, Fraser WD, Luo ZC - Primary birthing attendants and birth outcomes in remote Inuit communities - a natural

Behnam H, Zare M - Frequency of reproductive system disorders in high school students

VISIT TO THE EXHIBITION AREA 10.30 - 11.00

71 Sunday, March 8th Hall Casanova

08.30 - 10.30 ORAL PRESENTATIONS ENDOSCOPY AND OTHER SURGICAL TECHNIQUES IN REPRODUCTIVE MEDICINE

Chairmen: Garcia-Velasco Juan A., Querleu Denis

Asgharnia M, Nikpuri Z, Mona Oudi M, Tabar ZM, Hossieni A - Comparison the frequency of uterine anomalies between women with 2 and 3 or more miscarriage

Mehrafza M, Shademani K, Oudi M, Asgharnia M, Tabar MZ, Nikpuri Z - Laparoscopic hysterectomy outcome by using ligasure vessel sealing system

Ghafarnejad M, Soodabeh D, Narges I - Is it necessary to use skin or bowel graft for vaginal reconstruction? A simple approach

Uzhegova Z, Andreeva EN - Outcomes surgical correction of ambiguous genitalia

Cicinelli E, Tinelli R, Saliani N, Pinto V, Mitola P, Pastore A, Colafiglio G - Laparoscopy versus minilaparotomy in women with symptomatic uterine myomas: a prospective randomized study

Sayyah Melli M, Dastranj A, Vosog Tehrani S - Operative and pathologic characteristic of uterine myomas after treatment with chorionic gonadotropin- releasing hormone analog (Diphereline) and Cabergoline (Dostinex)

Del Pup L, Giorda G, Lucia E, Caserta L, Camisulli T, Volpe R, Serraino D - What is the best tool to perform vaginal vault cytology in hysterectomized gynaecologic cancer patients?

Kraemer B, Wallwiener M, Wallwiener C, Ahmad U, Marikar M, Rajab TK - Peritoneal adhesions: a prospective, multi-center study of the patients’ perspective

Gladchyuk I, Volyanskaaya A - Prophylaxis of postoperative adhesions after gynecological operations

Zaporozhan V, Gladchuk I, Rozhkovska N, Shitova A, Kozhakov V - Conservative myomectomy Scientific Programme

VISIT TO THE EXHIBITION AREA 10.30 - 11.00

72 Sunday, March 8th Hall Venice 1+2 13.30 - 13.45 CLOSING CEREMONY AND POSTER AWARDS

CLOSING CEREMONY

Hall Venice 1 Sunday, March 8th , 13.30

The Poster Awards will be assigned during the Closing Scientific Programme Ceremony

73 POSTER

ASSISTED REPRODUCTIVE TECHNOLOGY

P. 1 Psychological adjustment of infertile couples before medically assisted procreation treatment Valentino V, Conversano C, Lensi E, Tessieri D, Artini PG, Cela V, Genazzani AR, Italy

P. 2 Association between a point mutation of native LH and ovarian response to controlled stimulation with rFSH Clarizia R, Alviggi C, Pettersson K, Humaidan P, Conforti A, Fiorentino A, Cariati F, De Biaso G, De Placido G, Italy

P. 3 Cumulus cells parameters for oocyte quality Gneist N, Keck G, Trinkaus I, Gouma E, Leuchten B, Hanseroth K, Distler W, Germany

P. 4 Spontaneous secretion of brain-derived growth factor in granulosa cell cultures and zygote and early embryo culture medium Ruggiero M, Monteleone P, Casarosa E, Carletti E, Simi G, Di Berardino OM, Cela V, Genazzani AR, Artini PG, Italy

P. 5 Modulation of vascular endothelial growth factor expression by brain-derived neutrophic factor in cultured luteinizing human granulosa cells Parisen Toldin MR, Monteleone P, Casarosa E, Carletti E, Giretti MS, Simi G, Di Berardino OM, Genazzani AR, Cela V, Artini PG, Italy

P. 6 Use of the opponent method in IAD (Insemination artificial donor) for improving the scheduling of non-working days Garcia Rubio MJ, Martin Cabrejas B, Moreta Sanchez S, Serrano Olmedo MG, Moreno Scientific Programme Ceneira MM, Martin Caballero C, Lopez Salva A, Spain

P. 7 Controlled ovarian hyperstimulation with or without intrauterine insemination for the treatment of primary unexplained infertility Araujo C, Santo S, Aguiar A, Sousa S, Nunes J, Soares AP, Calhaz-Jorge C, Portugal

P. 8 Case report: pregnancy outcome following ICSI of oocytes with abnormal polar bodies extrusion Vucetich A, Boldi Cotti P, Chigioni S, Galofre Ballestreros G, Arcaini L, Italy

P. 9 Comparison of integrins expression profile in normal and ovariectomized mice endometrial Peyghambari F, Salehnia M, Forouzandeh Moghadam M, Rezazdeh Valujerdi M, Hajizadeh E, Iran

74 P. 10 Assisted hatching of mice embryos (Swiss Albino) by tyrode acid Dasuki D, Fauzia I, Haryadi D, Indonesia

P. 11 Plasma levels of the endocannabinoid, Anandamide, are moduled from ovulation to the first trimester of pregnancy in women undergoing IVF/ICSI-ET El-Talatini M, Taylor AH, Elson JC, Konje JC, UK

P. 12 Expression profiles of genes controlling maturation of sheep cumulus oocyte complexes follow vitrification Ebrahimi B, Rezazadeh Valojerdi M, Eftekhari Yazdi P, Baharvand H, Iran Scientific Programme P. 13 The mouse sperm changes after cryopreservation Hatami L, Movahedin M, Iran

P. 14 Progesterone on day hCG as a predictor of endometrial receptivity Wiweko B, Soebijanto S, Hestiantoro A, Natadisastra M, Indonesia

P. 15 IVF results in woman with one ovary Albu D, Albu A, Pelinescu-Onciul D, Romania

P. 16 Is embryo quality influenced by male's age? Rodriguez Aguera M, Prats L, Brassesco A, Cairò O, del Rio F, Rovira S, Gomez M, Brassesco M, Spain

P. 17 FSH levels and IVF results Iemmola A, Rubbino G, Caldaci L, Leonardi E, Raciti D, Merlo L, Palumbo MA, Italy

P. 18 Infertility, is it occupies today or even yesterday Dimitrakopoulos S, Andriotis A, Koliantzaki S, Sidiropoulou A, Sorras K, Saltamavros A, Bonas A, Konstantinos N, Sidiropoulos N, Greece

P. 19 Multiple pregnancy in an occyte donation program: predicitve factors Clua Obradò E, Tur R, Rodriguez I, Boada M, Martinez F, Luna M, Barri PN, Spain

P. 20 Combined therapy (carnitines, minerals, antioxydants and energy substrates) in the treatment of the male infertility Ouzounova I, Nikolova V, Ouzounova-Raykova V, Stanislavov R, Bulgaria

75 P. 21 Evaluation of treatment outcomes of infertile women with primary infertility due to hypogonadotropic hypogonadism in kowsar IVF center Motahari Hospital, Iran Ayatollahi H, Mehrzad Sadaghiani M, Iran

P. 22 Management of the quality of high-tech medical help in ob&gyn hospital Beleckaya I, Pogorelova A, Makhmudova G, Russia

P. 23 IUI results in couple infertility Albu D, Albu A, Pelinescu-Onciul D, Romania

P. 24 Embryotomy, a diachronic interventional obstetrical method of Hippocrates Dimitrakopoulos S, Andriotis A, Koliantzaki S, Papageorgiou E, Bonas A, Sorras K, Saltamavros A, Sidiropoulou A, Oikonomopoulos N, Konstantinos N, Sidiropoulos N, Greece

P. 25 The effect of intercourse around embryo transfer on pregnancy rate in ART cycles Aflatoonian A, Ghandi S, Tabibnejad N, Iran

P. 26 Synchronizing cell cycle of goat fibroblast by serum starvation causes apoptosis Dalman A, Eftekhari-Yazdi P, Valojerdi MR, Shahverdi A, Gourabi H, Janzamin E, Fakheri R, Sadeghian F, Iran

P. 27 The effects of Trifuralin on LH, FSH and testosterone hormone levels and testis histological changes in adult rats Shariati M, Ghavami M, Mokhtari M, Askari HR, Iran

P. 28 The alternative approaches to the management of female infertility Artymuk N, Kira E, Kondratieva T, Russia Scientific Programme

P. 29 Single versus double intrauterine insemination in stimulated cycles: a prospective randomized study Karimpour Malekshah A, Esmailnejad Malekshah A, Iran

P. 30 Low number of retrieved oocytes has a high negative impact in IVF success Aguiar A, Cordeiro I, Leal F, Soares AP, Nunes J, Sousa S, Carvalho M, Calhaz-Jorge C, Portugal

P. 31 Radionuclide hysterosalpingography is not useful for infertility investigation Wanggren K, Jacobsson H, Wramsby H, Larsson S, Lundberg S, Bremmer S, Sweden

76 P. 32 DAZ and PRM2 transcripts in semen: non-invasive molecular markers Sadeghi MR, Modaresi MH, Akhondi MM, Aslani F, Iran

P. 33 The prospects of predicting the outcomes of IVF and ICSI in infertile married couples Yavorovskaya K, Nazarenko TA, Amirova AA, Mishiyeva NG, Zarubina TV, Kolesnicenko TV, Russia

P. 34 Case report (very rare cognital anomali) Nazari Foroushani MA, Iran

P. 35 Scientific Programme Clinical and laboratory parameters of patients with positive and negative results of in vitro fertilization Samoilova AV, Milaev SG, Gunin AG, Russia

P. 36 Apoptosis in human spermatozoa from subfertile men before and after vitrification Peirouvi T, Sadaghiani Mehrzad M, Farahnaz N, Siamak S, Iran

P. 37 Relationship between morphological and kinetic properties of human sperm Ljiljak D, Krile L, Croatia

P. 38 The impact of endometrial thickness, technical ET catheter issues and day 14 serum HCG after ovum pick up on the implantation rate and pregnancy outcome Elbeltagy K, Taguchi S, Funabiki M, Ujino H, Hayashi T, Nakamura Y, Japan

P. 39 Does exist a role of male factor in recurrent pregnancy loss? Riviello C, Rizzello F, Pianigiani E, Spitaleri M, Coccia ME, Italy

P. 40 Effect of semen characteristics on the success of treatment by intrauterine insemination method Moghaddam AE, Malakshah AK, Iran

P. 41 Importance of oxygen in in vitro ovarian follicle culture Connolly JM, Hynes AC, Ireland

P. 42 A pilot study of the usuflness of antioxidant therapy on follicular microenvironment Vento M, Guglielmino MR, Di Pietro C, Borzì P, Spina V, Santonocito M, Giliberto S, De Palma A, Garofalo MR, Poma G, Purrello M, Scollo P, Italy

P. 42 bis Effect of Hysteroscopy on ICSI Outcome in Patients with Previous ICSI Failure Mehrafza M, Oudi M, Asgharnia SM, Tabar ZM, Nikpuri Z, Shademani K, Hossieni A, Iran

77 POSTER

GENITAL INFECTIONS

P. 43 Safety evaluation of a widely used rinse cleanser in intimate hygiene Benvenuti C, Camana MG, Mortara E, Tacconi E, Italy

P. 44 Visual analysis of vaginal cell binding and retention of a gynecological douche Braga PC, Spallino A, Dal Sasso M, Sturla C, Culici M, Italy

P. 45 Efficacy of proanthocyanidis combined with probiotic lactobacillion symptoms in re- current cystitis De Leo V, Benvenuti C, Italy

P. 46 Prevalence of Chlamydia trachomatis as serious pathogen of the reproductive sy- stem among young sexually active girls without genital complains Ouzounova-Raykova V, Iordanov D, Mitov I, Ouzounova I, Bulgaria

P. 47 Vaginal gel adsorption and retention by human vaginal cells: visual analysis by me- ans of inorganic and organic markers Culici M, Dal Sasso M, Spallino A, Sturla C,Braga PC, Italy

P. 48 Comparison of human papillomavirus DNA testing and repeat Papanicolau test in women with low-grade cervical cytologic abnormalities Demalia E, Cerekja A, Bylykbashi E, Albania

P. 49 Anti HPV vaccination program and reactions of an unprepared population from a de- veloping country Scientific Programme Mocuta D, Pop T, Brezovsky H, Antal L, Craiut D, Romania

P. 50 A comparison between the pathogens and their risk factors in patients with and wi- thout bacterial vaginosis Kashanian M, Kazemzadeh M, Sedaghat M, Iran

P. 51 Treatment of bacterial vaginosis: a comparison of oral metronidazole and metronida- zole vaginal gel Afshari P, Naderan Tahan M, Iran

P. 52 Therapeutic divalent vaccination against CIN2, CIN3 and HPV16+ cervical cancer Giannios J, Peristeris J, Greece

78 P. 53 Phenotype of peripheral blood lymphocytes and cytokine status in patients with acu- te salpingoophoritis Tanko O, Benuk V, Samoylova MV, Blagoveshchensky E, Ukraine

P. 54 Controlled study on thymol+eugenol vaginal douche versus econazole in vaginal candidosis and metronidazole in bacterial vaginosis Sosto F, Benvenuti C, Canva Study Group, Italy

P. 55 Behavior study and HIV prevalence among pregnant women in Georgia Shengelia L, Bokhua Z, Asatiani T, Georgia

P. 56 Scientific Programme Gardnerella vaginalis adhesion to human vaginal cells: inhibitory effect of thymol Culici M, Dal Sasso M, Spallino A, Sturla C, Braga PC, Italy

P. 57 The action of Glycyrrhizinic acid on the mucosa of low genital tract in virus infec- tions Shurshalina AV, Sukhikh GT, Krechetova LV, Ziganshina MM, Kusmartseva OF, Russia

P. 58 Antiradical activity of calendula officinalis extract: investigation by means of elec- tron paramagnetic resonance (EPR) spectroscopy Braga PC, Spallino A, Culici M, Dal Sasso M, Falchi M, Italy

P. 59 Adnexal inflammatory tumors- therapy decisions according to the value of CA 125 Nikolic B, Serbia

P. 60 Is it possible to score the severity of endometrial inflammation by hysteroscopy in women with chronic endometritis? A retrospective clinical study Cicinelli E, Tinelli R, Colafiglio G, Saliani N, Pastore A, Sciorsci R, Resta L, Italy

P. 61 Tactics of organ-saving operative treatment at purulent pelvic inflammatory disea- ses Utkin E, Podonina NM, Russia

POSTER

CONTRACEPTION

P. 62 Contraception experiences of young women in their first years of marriage Fathizadeh N, Tashi Sh, Abedi HA, Kazemi A, Iran

79 P. 63 The evaluate of causes of unwanted pregnancy in pregnant's women Motamedi M, Iran

P. 64 The history of contraception and familial planning Dimitrakopoulos S, Andriotis A, Koliantzaki S, Sorras K, papageorgiu E, Saltamavros A, Sidiropoulou A, Oikonomopoulos N, Sidiropoulos N, Greece

P. 65 Contraceptive awareness, knowledge and practice among men in Georgia Kristesashvili J, Khomassuridze A, Georgia

P. 66 The safety of two rods sino-implant versus six rods norplant contraceptive measured by Biomedic indicator Dasuki D, Wardoyo H, Widad S, Indonesia

P. 67 Association of bleeding pattern and estradiol level depot medroxy progesteron ace- tate users Dasuki D, Wardoyo H, Hadi C, Widad S, Indonesia

P. 68 Effect of hormonal contraception Planibu versus depo progestin on liver function and lipid profile Dasuki D, Wardoyo H, Widad S, Indonesia

P. 69 Searching for the "ideal contraception" - what do women really need? Grigore M, Hamod C, Romania

P. 70 Endometrial nuclear factor-kappa B activation in patients with breakthrough bleeding during continuous oral contraceptive use Maia H Jr., Casoy J, Athayde C, Correia T, Coutinho EM, Brazil Scientific Programme

P. 71 The effect of hysterectomy or levonorgestrel-releasing intrauterine system on urinary symptoms and vaginal wall prolapses women with menorrhagia - a 10-year follow-up study Heliovaara-Peippo S, Halmesmaki K, Hurskainen R, Grenman S, Kivela Eija A, Tuppurainen TM, Paavonen J, Finland

POSTER

PREGNANCY

P. 72 Preconception and prenatal folic acid use in pregnant women who refer to health clinic of Ahvaz Afshari P, Saki G, Sadeghi S, Hekmat K, Iran

80 P. 73 The abortion in the course of history Dimitrakopoulos S, Andriotis A, Koliantzaki S, Papageorgiou E, Bonas A, Sorras K, Salta- mavros A, Sidiropoulou A, Oikonomopoulos N, Konstantinos N, Sidiropoulos N, Greece

P. 74 The role of recombinant human erythropoietin in the treatment of iron. Deficiency anemia of pregnancy Dimitrakopoulos S, Koliantzaki S, Sidiropoulou A, Sorras K, Papageorgiou E, Saltamavros A, Goula K, Tseliou P, Sidiropoulos N, Greece

P. 75 Combined screening for Down's syndrome in the first trimester of pregnancy with nuchal translucency (NT), nasal bone (NB) and maternal serum free beta-hCG and

PAPP-A under Fetal Medicine Foundation criteria in Tuscany Scientific Programme Luchi C, Nanini C, Schifano M, Parrini D, Genazzani AR, Italy

P. 76 BDNF (Brain-Derived Neutrophic Factor) and first trimester of pregnancy in hu- mans Luchi C, Ninni F, Nanini C, Schifano M, Freschi L, Casarosa E, Luisi M, Genazzani AR, Italy

P. 77 A pregnancy in an unevaluated and untreated Cushing's syndrome Pop T, Craiut D, Herczegh R, Mocuta D, Lacziko S, Toma M, Romania

P. 78 Treatment of cervical insufficiency abortion by autologeous human peripheral blood mononuclear cell, modern trend Mohammed Ali AF, Rafik M, Mohammed Ali S, Hussein M, Ali Farid L, Egypt

P. 79 Comparison between the clinical and Johnson & Toshach's methods in correct esti- mation of fetal weight Ghafarnejad M, Ansarian H, Bahmanabadi A, Nasehi L, Iran

P. 80 Factors causing incorrect estimation of fetal weight, when using Johnson & Toshach method Ghafarnejad M, Ansarian H, Bahmanabadi A, Nasehi L, Iran

P. 81 Effect of isradipine on spontaneous and prostaglandin F2alpha-induced contractility of myometrium from late pregnant rat Kutlu S, Kumru S, Nalbant M, Ozcan M, Alcin E, Gurates B, Ayar A, Turkey

P. 82 Klippel-Feil Syndrome associated with Dandy Walker Complex and Neural Tube De- fect Pirino A, Cosmi E, Bandiera P, Montella A, Italy

81 P. 83 Recurrent pregnancy loss: an innovative diagnostic and therapeutic approach Riviello C, Rizzello F, Spitaleri M, Coccia ME, Italy

P. 84 Possible role of bacterial and chlamydial infection in spontaneous abortions Bogavac M, Radulovic A, Relic G, Serbia

P. 85 Perinatal findings of proximal trisomy 13q and distal trisomy 20q due to a 3:1 segre- gation of maternal reciprocal translocation t(13;20)(q14;q13) Bouayed Abdelmoula N, Lamine L, Meddeb M, Louati R, Amouri A, Rebai T, Tunisia

P. 86 Urinary infection in pregnancy and low birth weight in pregnant women who refer to private hospitals in Ahvaz Karimi L, Afshari P, Sadeghi S, Iran

P. 87 Comparison study of intravenous normal saline with and without dextrose on the outcome of labor in nullipara Hekmat K, Najar S, Hatamirad R, Iran

P. 88 The implication of the apoptosis like a remodelation factor for the vasculo and angio- genesis in early pregnancy Novac L, Niculescu M, Cernea N, Tudorache S, Manolea M, Comanescu A, Iliescu D, Capi- tanescu R, Cernea D, Novac M, Romania

P. 89 Spontaneous abortions among "special" women Martin Cabrejas BM, Garcia Rubio MJ, Gargantilla Madera P, Serrano Olmedo MG, Moreno Cebeiro M, Martin Caballero C, Spain

P. 90 Eklampsia in the third trimester of pregnancy and systemic lypys erythematosus. A Scientific Programme case report Dimitrakopoulos S, Koliantzaki S, Sidiropoulou A, Mouratidou A, Protopapas P, Papageor- giou E, Sorras K, Saltamavros A, Oikonomopoulos N, Sidiropoulos N, Greece

P. 91 Breech presentation and parity Katsetos Ch, Karamousà E, Panagopoulos P, Karadaglis S, Katsoulis M, Greece

P. 92 Delivery of a estimated 34 week old extrauterin pregnancy Habelsberger A, Tews G, Austria

P. 93 Nitric oxide pathway adaptive changes related to intrauterine growth, gestational age at birth and mode of delivery Pisaneschi S, Sanchez AM, Garibaldi S, Goglia L, Tosi V, Begliuomini S, Genazzani AR, Coceani F, Simoncini T, Italy

82 P. 94 The twin pregnancies in Kosovska Mitrovica Relic G, Bogavac M, Serbia

P. 95 Cesarean section as a operative method of delivery completition in patient with PIH Daneva-Markova A, Nikolova T, Nikolovska E, Trajkova K, Republic of Macedonia

P. 96 Unrecognised uterine scars in a case report of third trimester spontaneous uterine rupture Panagopoulos P, Katsetos Ch, Samolis S, Papastefanou I, Katsoulis M, Greece

P. 97

The association of humoral immunity and iron parameters in the third trimester of Scientific Programme pregnancy Naderi N, Sobhani SA, Etaati Z, Mirani S, Saberi P, Shiroodi M, Iran

P. 98 The relationship between maternal nutrition during pregnancy and hypertensive di- sorders Mortazavi F, Koshki A, Akaberi A, Iran

P. 99 Case report: pregnancy in secondary infertile patients after office hyseroscopy cesa- rean scar section with 5 French bipolar instrument Accardi A, Accardi M, Pinto L, Petronio P, Petronio M, Italy

P. 100 Evryfon the Knidios, the founder of scientific medicine and of obstetrics-gynecolo- gy Dimitrakopoulos S, Andriotis A, Saltamavros A, Koliantzaki S, Papageorgiu E, Bonas A, Sorras K, Sidiropoulou A, Sidiropoulos N, Greece

P. 101 Women's exercise trend before pregnancy till 3 months after delivery in west of Tehran Taavoni S, Esmaelzadeh S, Aahmadi Z, Haghani H, Iran

P. 102 In vitro activity of L-Arginine on homocysteine induced myometrial contractility Rizzo A, Trisolini C, Colola C, Mutinati M, Minoia G, Spedicato M, Pantaleo M, Punzi S, Roscino MT, Matteo M, Sciorsci RL, Italy

P. 103 Evaluation of relationship between helicobacter pylori infection and gastrointestinal symptoms during pregnancy Shivarani S, Shahmohamadi F, Iran

P. 104 A comparison between different episiotomy types during vaginal delivery Dimitrakopoulos S, Koliantzaki S, Sidiropoulou A, Saltamavros A, Sorras K, Oikonomopou- los N, Bonas A, Papageorgiou E, Sidiropoulos N, Greece

83 POSTER

GENETICS AND STEM CELLS

P. 105 Genetic screening in infertile couples Papini F, Simi P, Viegi E, Di Berardino OM, Simi G, Valentino V, Cela V, Genazzani AR, Artini PG, Italy

P. 106 Expression of Bax, Bcl-2, p53 and Survivin in heat treated testis of mouse Absalan F, Movahedin M, Javad Mowla S, Iran

P. 107 Assessment of gene expression pattern in germ cell development from embryonic stem cell Makoolati Z, Movahedin M, Forouzandeh-Moghadam M, Iran

P. 108 Transcriptional and epigenetic analysis indicates ESX1L gene as a diagnostic marker for Sertoli cell only syndrome Miozzo M, Gallina A, Moretti M, Bonaparte E, Sirchia S, Grati F, gazzano G, Nerva F, Con- talbi G, Colpi G, Italy

P. 109 Some genetic markers of hypothalamic dysfunction with reproductive disorders in women from Eastern Serbia Labigina A, Suturina L, Kolesnikova L, Shenin V, Nesterova D, Demidova L, Russia

P. 110 Screening for chromosomal abnormalities inn 330 infertile couples undergoing ICSI Bouayed Abdelmoula N, Meddeb M, Amouri A, Rebai T, Tunisia

P. 111 Media-usefulness and importance in giving informations about stem cells Scientific Programme Nikolic MV, Serbia

P. 112 Human umbilical cord blood and umbilical cord mesenchymal stem cells can contri- bute to liver regeneration in an animal model of chemical-induced injury Chioato T, Bizzaro D, Tomat S, Bo P, Russo FP, Masier A, Pellicanò D, Conconi MT, Parni- gotto PP, Burra P, Italy

P. 113 Assessment of DAZ and Oct-4 genes expression in human spermatogonial stem cells after in vitro colonization Mirzapour T, Mansoureh M, Tengku Azmi I, Morteza K, Vahid AH, Nowroozi MR, Rafeian S, Iran

P. 114 The effect of co-culture with sertoli and STO cells on spermatogonial stem cell colo- nization Mohamadi M, Movahedin M, Koruji M, Iran

84 POSTER

BASIC AND CLINICAL ENDOCRINOLOGY

P. 115 Paroxetine increases brain-derived neurotrophic factor (BDNF) in amenorrheic wo- men Bucci F, Cubeddu A, Giannini A, Merlini S, Lenzi E, Begliuomini S, Ninni F, Pluchino N, Genazzani AR, Italy

P. 116 The effects of ciproterone acetate (CA) or drospirenone (DRSP) on acne in patients Kvashilava N, Kristesashvili J, Pkhaladze L, Kvaliashvili S, Georgia Scientific Programme P. 117 The estrogen metabolism in women with uterine myoma and efficacy of levonorge- strel-releasing intrauterine system Mirena Suturina L, Ermolova E, Sholohov L, Kovalenko I, Russia

P. 118 Hyperandrogenemia influences the prevalence of the metabolic syndrome abnorma- lities in adolescents with the polycystic ovary syndrome Perini D, Fruzzetti F, Lazzarini V, Parrini D, Genazzani AR, Italy

P. 119 Serum prolactin level and depression in postmenopausal women Slopien R, Warenik-Szymankiewicz A, Kostrzak A, Meczekalski B, Poland

P. 120 Serum prolactin level and prolactin recovery (%) after polyethyleneglycol (PEG) pre- cipitation in women with proilactinoma and normal regular cycles with hyperprolac- tinemia Kostrzak A, Warenik-Szymankiewicz B, Meczekalski B, Poland

P. 121 The estrogen metabolism disorders in women with uterine myoma and infertility Suturina L, Kolesnikova L, Skljar N, Labigina A, Sholohov L, Russia

P. 122 Estrogen and endometrial cells movement: possible role of focal adhesion kinase Flamini MI, Sanchez AM, Genazzani AR, Simoncini T, Italy

P. 123 Rapid signaling of estrogen to wave1 controls neuronal spine formation via the actin cytoskeleton Sanchez AM, Flamini MI, Genazzani AR, Simoncini T, Italy

P. 124 The prevalence of non-classical congenital adrenal hyperplasia due to 21-hydroxyla- se deficiency in Greek women with acne Patsouras K, Trakakis E, Papadavid L, Bassios G, Grammatikakis I, Salamelekis G, Kas- sanos G, Greece

85 P. 125 Evaluation of the relation between dehydroepiandrosterone Ebrahimian F, Moghimi, Iran

P. 126 The effect of progesterone on the gene expression of insulin-like growth factor-II in human decidual stromal cells and villous trophoblast cells of early pregnancy in vi- tro Li S, Li L, Cao Z, Peng Z, Han Z, China

P. 127 Effect of Trigonella foenum-gracum seed extract on concentration of testosterone and spermatogenesis Mokhtari M, Shariati M, Iran

P. 128 Influence of endogenous testosterone on hypertension in aging male Barac B, Vujovic SZ, Stojanovic MM, Ivovic MS, Tancic M, Barac MM, Marina Lj, Drezgic M, Serbia

P. 129 Relationship of hormonal status and bone state in men Povoroznyuk V, Orlyk TV, Kreslov YA, Ukraine

P. 130 Structural-functional state of bone in men of different age Povoroznyuk V, Kreslov Yeugen A, Ukraine

P. 131 Activity mechanism of curcumin and pentagamavunon on steroidogenesis and apop- tosis in the luteal cell culture Syamsul Hadi R, Kardasih S, Aswin S, Dasuki D, Indonesia

P. 132 Family history of obesity among first-degree relatives influences phenotypic features of polycystic ovary syndrome patients Scientific Programme Albu A, Radian S, Constantin M, Florea S, Grigorescu F, Fica S, Romania

P. 133 Assessment of the impact of severe premenstrual disorders on work absenteeism and productivity Heinemann K, Damonte Khoury C, Filonenko A, Heinemann LAJ, Germany

P. 134 Brain-derived neutrophic factor in reproductive aberration and its correction by ce- rebrolysin Mohammed Ali AF, Kamel S, Ali Farid S, Hussein M, Alhosainy A, Hassan A, Egypt

P. 135 Clomiphene citrate-resistant polycystic ovarian syndrome: focus on ovarian (follicu- lar and stromal) volume and hormonal status Ancuta E, Anghelache-Lupascu I, Anton E, Ancuta C, Romania

86 P. 136 Testosterone increases the expression of IL-6 and MCP-1 in 3T-L1 adipocytes throu- gh the activation of NF-kB Su C, Lin J, China

P. 137 Clinical and biochemical improvement of acromegaly after pregnancy Veltri F, Tartaglione L, Cimino V, Bianchi A, Giampietro A, Milardi D, D'Uonnolo A, Pontecor- vi A, De Marinis L, Italy

P. 138 The effect of treatment with growth hormone on fertility outcome in eugonadal wo- men with growth hormone deficiency: report of four cases Giampietro A, Milardi D, Bianchi A, Cimino V, Fusco A, Marana R, Pacentini S, Pontecorvi

A, De Marinis L, Italy Scientific Programme

P. 139 Weak estrogen administration restores hypothalamo-pituitary function in hypothala- mic amenorrhea Lanzoni C, Ricchieri F, Santagni S, Rattighieri E, Campedelli AL, Chierchia E, Di Monte I, Farinetti A, Jasonni VM, Genazzani AD, Italy

P. 140 Evaluating histological modifications of testis and spermatogenesis in adult male rats on finasteride Khatamsaz S, Atrian H, Mokhtari M, Sarvarehazimzadeh B, Iran

P. 141 Interests of exploration of sperm and sex hormones among haemodialysis patients Ajina M, Zaouali M, Benjamaa N, Loussaief W, Frih A, Elmay M, Zbidi A, Saad A, Tunisia

P. 142 Selective estrogens receptor modulators regulate endometrial cell migration via the ER/galpha 13 and RhoA/Rho Kinase/Moesin signaling pathway Flamini MI, Sanchez AM, Genazzani AR, Simoncini T, Italy

P. 143 Outcomes of ovarian fucntion and pregnancy in women with lupus nephritis treated with immunosuppressive agents Park MC, Lee JY, Chung SJ, South Korea

P. 144 The study of girl students knowledge about hygiene of menstruation period and some related factors Athari F, Zareay R, Agaey N, Iran

P. 145 Rapid non-genomic alterations in the microtubule cytoskeleton of human endome- trial epithelial cells in response to steroid hormones Dockery P, Harvey BP, Thompson K, Burke M, Ireland

87 P. 146 Nostalgia to ovarian wedge resection in PCOS: a modified selective laparoscopic technique El Guindy AED, Egypt

P. 147 The female body during the period of Ancient Greece Assimomytis A, Assimomytis A, Stavrinoudakis E, Balafoutas, Farmakidis, Ricevuti, Frigo, Greece

P. 148 Investigation of prostaglandin Transporter in Uterine Epithelial Cells Fitzgerald A, Quinlan L, Hynes A, Ireland

POSTER

REPRODUCTIVE IMMUNOLOGY AND ENDOMETRIOSIS

P. 149 Human lutropin receptor and HCG-b subunit chimera Saxena B, Hao M, Kinsland C, Rathnam P, USA

P. 150 The effects of pregnancy related immunomodulation on dendritic cells antigen pre- sentation Moazzeni SM, Bozorgmehr M, Zarnani AH, Iran

P. 151 The chemokine receptor CCR5del32 variation in tubal factor infertility Laisk T, Peters M, Haller-Kikkatalo K, Salumets A, Estonia

P. 152 The expressions of CD200 and CD200R antigens on myeloid and lymphoid dendritic cells during the menstrual cycle and normal pregnancy Darmochwal-Kolarz D, Rolinski J, Kolarz B, Leszczynska-Gorzelak B, Oleszczuk J, Poland Scientific Programme

P. 153 Regulatory T cell level between normal pregnant and abortus patients Sumapraja K, Suheimi I, Hestiantoro A, Indonesia

P. 154 A quantitative changes of T, B and NK cells between fertile and infertile women Ghafourian Boroujerdnia M, Esmailvandy K, Sapharpour V, Iran

P. 155 IL-17/IL-23 are actively involved in the immuno-ptahogenesis of uro-genital diseases caused by Ch. Trachomatis Shavlakadze N, Shavlakadze M, Dorgoshidedze B, Georgia

P. 156 The role of sexual transmitted infections on factors local apoptosis at the progres- sing of endometrial hyperplastic processes Makhmudova G, Pogorelova A, Russia

88 P. 157 Molecular mimicry between sperm and bacteria Prabha V, Chaudhary N, Kaur S, Beakta S, Sandhu R, Singh A, Kala S, India

P. 158 Interleukin-2 receptor beta gene C627T polymorphism in Korean women with endo- metriosis: a case control study Choi YM, Lee GH, Lee TH, Hur JY, Oh ST, Lee KS, Lim YT, Korea

P. 159 Downregulation of matrix degradating and pro-angiogenic proteins in endometriosis by histone deacetylase inhibitors Imesch P, Canonica C, Schneider M, Fink D, Fedier A, Switzerland

P. 160 Scientific Programme The microsatellite polymorphism (tttta) in intron 14 of the CYP 19 gene inn Java wo- men with chocolate cyst Sawarno A, Sadewa AH, Dasuki D, Indonesia

P. 161 "PGR-1 Hot-Dog": A new microsurgical technique of the experimentally-induced endometriosis in rats Gonzalez Ramos P, Royo Manero P, Pastor Oliver C, Calleja Aguayo E, De Martino A, Go- dino J, Bejarano Lasuncion P, Manero J, pecondon A, Vicente B, Gracia Romero J, Ortega J, Alcazar Zambrano JL, Fabre Gonzalez E, Spain

P. 162 Evidence of complement C3 protein in endometriosis Ribeiro MA, Pinto A, Silva Carvalho JL, Almeida H, Portugal

P. 163 Negative chlamydial antibody titre strongly correlates with endometriosis symptoms in women with presumed acute pelvic inflammatory disease Greenhouse P, Evans A, UK

P. 164 Clinical effects of Mistletoe therapy in postmenopausal endometriosis patients Lim YT, South Korea

P. 165 Increased production of 17beta-estradiol in endometriosis lesions is the result of impaired metabolsim Delvoux B, Groothuis P, D'Hooghe T, Kyama C, Dunselman G, Romano A, The Netherlan- ds

P. 166 Use of immune and hematotropic effect of placenta in experimental model of miscar- riage Goltsev A, Dubrava TG, Ostankova LV, Lutsenko ED, Ukraine

89 POSTER

ONCOGENESIS, APOPTOSIS, CANCER AND REPRODUCTION

P. 167 The teratologic effect of Vincristine at during organogenesis in newborn mice Hejazi S, Iran

P. 168 Toxicity effect of Vincristine on cerebellar Purkinje cells at during lactivorous in ne- onate mice Hejazi S, Iran

P. 169 Neutrophil gelatinase-associated Lipocalin is preferentially expressed in human en- dometrial hyperplasia Chu ST, Lee YC, Tzeng WF, Taiwan

P. 170 Toxicity effect of vincristine-treatment on mice testis tissue Hejazi S, Safavi S, Aliinasab, Iran

P. 171 Infections at the pathogenesis of endometrial hyperplastic processes Makhmudova G, Pogorelova A, Russia

P. 172 Genetic polymorphism of estrogen metabolizing enzymes in women with endometrial cancer and different body weights Artymuk N, Ilenko E, Gulyaeva L, Kcharenkova E, Russia

P. 173 Effect of ovarian hyperstimulation on endometrial apoptosis during implantation pe- riod Beigi Boroujeni M, Iran Scientific Programme

P. 174 Investigation of DNA damage in exfoliated human mammary epithelial cells recovered from lactating mothers in Istanbul Sandal S, Tug N, Demirci Y, Ayvaci H, Yilmaz B, Turkey

P. 175 Abnormal uterine bleeding in premenopausal women: when should be investigate the endometrium? Iram S, Ewies A, UK

P. 176 Comparative knowledge of breast self examination in midwifery and nursing student Islamic Azad University Karaj Branch Ashkvary P, Parsinia M, Babai GR, Amiri M, Khodaverdiyan S, Iran

90 P. 177 Effects of androgens on breast cancer cell migration and metastasis Giretti MS, Goglia L, Flamini M, Sanchez AM, Mannella P, Pisaneschi S, Tosi V, Genazzani AR, Simoncini T, Italy

P. 178 Apoptosis-related genes expression of ovary after treatment with amifostine Barekati Z, Gourabi H, Iran

P. 179 Effect of dydrogesterone, dehydro-dydrogesterone, progesterone and medroxypro- gesterone acetate on T47D breast cancer cell migration and invasion Tosi V, Pisaneschi S, Goglia L, Genazzani AR, Simoncini T, Italy Scientific Programme P. 180 Role of estrogen on breast cancer cell movement via the activation focal adhesion kinase Sanchez AM, Baldacci C, Flamini MI, Genazzani AR, Simoncini T, Italy

P. 181 Radiotermometric research of breast in different phases of menstrual cycles Mustaphin Chingis K, Russia

P. 182 Adhesiogenesis is associated with differential mRNA expression of metabolic ge- nes Wallwiener M, Wallwiener C, Kraemer B, Kansy JK, Petri N, Rajab TK, Germany

P. 183 Diagnosis of breast cancer of the post menopausal women and psycho-sexual pro- blem Buda F, Buda C, Messina G, Italy

P. 184 Complete hydatidiform mole with a surviving coexistent twin: a case report Caspani G, Greppi P, Galluzzi A, Telloli P, Pellegrino A, Italy

P. 185 Evaluation of Psychiatric Morbidity, Life stresses and Locus of Control in a sample of Egyptian cancer breast female patients El-Serafi D, Zaki N, El-Missiry A, Saad A, El-Nahas G, Khalil A, Egypt

P. 186 Effect of two-months treatment with Klamin, a Klamath algae extract, on the general well-being, antioxidant profile and oxidative status of postmenopausal women Ricchieri F, Santagni S, Rattighieri E, Scoglio S, Benedetti S, Canino C, Lanzoni C, Chier- chia E, Jasonni VM, Genazzani AD, Italy

91 ART outcome Sexual and Contraception Hall Casanova medicine Menopause Oral Presentations Oral Presentations Oral Presentations Oral Presentations Laboratory aspects in psychological aspects of human reproduction factors influencing ART ART factors influencing Ovulation induction and Hall Casanova Oral Presentations Oral Presentations Oral Presentations New frontiers in reproductive Basic and clinical endocrinology and Basic medicine Round Table Round Table Round Table Endometriosis Special Session Metabolic syndrome Hall Goldoni/Vivaldi delivery Cancer and reproduction New aspects in reproductive reproduction Round Table Round Table Round Table Early pregnancy loss Hall Goldoni/Vivaldi Imaging technology in Complicated pregnancy and of HRT Life in space Hall Venice 3 Hall Venice Plenary Lecture Plenary Session Plenary Session Sponsored by IMS BAYER SCHERING BAYER BAYER SCHERING BAYER con estroprogestinici Novità in contraccezione Corso di Aggiornamento Corso di Corso di Aggiornamento Corso di screening SERONO

14.00-14.30 14.30-16.00 th

Hall Venice 3 Hall Venice th Plenary Lecture Plenary Session Plenary Session Educational Course The menopause transition and beyond Genetics and stem cells Menopause and aging: critical review of the effects Menopause and aging: critical review of the effects Controversie, confronti, condivisioni in contraccezione Endometriosis: from disease to diagnosis Theory and practice of preimplantation genetic New opportunities in gonadotrophins treatment Friday, March 6 Friday, Thursday, March 5 Thursday, Brussels Oncology in Europe miscarriage 09.00-10.40 08.30-09.00 Hall Venice 2 Hall Venice Plenary Lecture Plenary Lecture Hall Venice 2 Hall Venice Plenary Session Plenary Session Plenary Session Scientific Programme and psychological aspects Hormonal treatment of recurrent Ovulation induction and embryo quality Donor sperm, egg and embryos-Clinical Cryopreservation and in vitro maturation The challenges for reproductive medicine Teleconference European Parliament in Teleconference IBSA Plenary Session Opening Lecture Perinatal medicine BAYER SCHERING BAYER Memorial Speeches Sponsored Symposium Sponsored Symposium A fresh look at contraception A In memory of Luigi Mastroianni Future trends in reproductive medicine Official Opening and Welcome Speeches Official Opening and Hall Venice 1 Hall Venice ISGE senescence Fostimon: clinical findings with a new type of human FSH reproduction Symposium Hall Venice 1 Hall Venice endocrinology Endocrinology Plenary Lecture Plenary Lecture developing world Plenary Session Plenary Session Plenary Session Infectious diseases and human New horizons in gynaecological Obstetrics and Gynecology in the Rapid signalling of steroid receptors PCO’s clinical consequences from birth to PCO’s 11.00-13.00 10.30-11.00 14.00-16.00 16.15-18.45 10.00-10.10 10.10-10.30 11.00-13.00 10.10-10.40 14.30-15.00 15.10-17.10 17.30-19.30 08.30-10.00

92 research Medicine Syndrome Symposium Hall Casanova Hall Casanova Polycystic Ovary Of Reproductive Oral Presentations Oral Presentations Oral Presentations Infertility in Portugal: Portuguese Society the reproductive tract Endoscopy and other surgical techniques in Infectious diseases of reproductive medicine epidemiology, laws and epidemiology, reproduction Round Table Special Session aspects of human Oral Presentations Oral Presentations Socio-environmental Hall Goldoni/Vivaldi Hall Goldoni/Vivaldi laboratory techniques implantation to delivery gynaecological practice Pregnancy: from embryo The assisted reproduction Sexual Medicine: impact on Scientific Programme ISPOG SIERR Estretol obstetrics gynaecology Symposium Symposium PANTARHEI Hall Venice 3 Hall Venice CRYO-SAVE contraception Hall Venice 3 Hall Venice Young at heart Young Plenary Session ultimate solution? BAYER SCHERING BAYER Sponsored Lecture Sponsored Lecture Sponsored Symposium

th th Glimpses of psychosomatic obstetrics and Women’s well being in the focus: role of Women’s The estrogen agonistic/antagonistic properties of Cord blood benefits for regenerative medicine and Human oocytes cryopreservation: is vitrification the Sunday, March 8 Sunday, Poster Session and Venetian Cocktail Poster Session and Venetian Saturday, March 7 Saturday, Closing Ceremony and Poster Awards Closing Ceremony and Poster infertility therapies Hall Venice 2 Hall Venice Hall Venice 2 Hall Venice Plenary Lecture Plenary Lecture Special Session Plenary Session Plenary Session Diagnostic and surgical problems in Laparoscopic myomectomy still more Adenomyosis:past, present and future Endometriosis: surgical and integrated Endoscopy and robotic surgery update successful than non-surgical approaches Plenary Session medicalmente assistita Special Session in Italian connected ART: the importance of National and European Registries ART: preservation Hall Venice 1 Hall Venice Hall Venice 1 Hall Venice Plenary Lecture Plenary Lecture Plenary Session Plenary Session Plenary Session hyperandrogenisms Techniques since 1978: Techniques Aspetti etici della riproduzione umana: dalla contraccezione alla procreazione ART results in USA and Europe results in USA ART Ovarian aging and ovarian tissue Evolution of Assisted Reproductive Evolution of 30 years since the first test tube baby Polycystic Ovary Syndrome and other Women-centered healthcare on line: get Women-centered 11.00-13.00 17.30-19.00 08.30-10.00 10.10-10.40 15.10-17.10 14.30-15.00 11.00-13.30 13.30-13.45 08.30-10.30

93 Notes Notes

94 Notes Notes

95 Notes Notes

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