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EDITION OCTOBER 2017

ACR DO NOT MISS

ACR 2017 SAN DIEGO

ORAL PRESENTATIONS AND POSTERS

MENTOR/MENTEE MEETINGS

NETWORKING EVENT

WORLD ARTHRITIS DAY

ISSN 2521-7852 EDITORIAL

Dear young rheumatologists and researchers in rheumatology, DIRECTORY

We are happy to present you a new issue of EMEUNEWS with a selection of not to be missed ACR 2017: ORAL PRESENTATIONS & POSTERS 4 abstracts at this year´s ACR annual meeting. Basic Research I Basic Research II The ACR congress is one of the largest scientific Hilfslinien anzeigen über Menu: RA I events in rheumatology. As this year’s congress is RA II fast approaching, we provide you with a selection of oral presentations and posters that we consider to be RA III Ursprungsform noteworthy. This selection is a personal one by the Psoriatic Arthritis contributors and cannot possibly hope to capture all of Axial Spondyloarthritis the exciting new research to be presented, however, SLE and APS we hope it provides an overview of some interesting Other connective tissue diseases im Menü über: sessions. Imaging Start | Absatz | Listenebene In addition, this Newsletter contains details about Crystal Arthropathies EMEUNET events organized during the Congress. Osteoarthritis & Osteoporosis Paediatric Rheumatology EMEUNET is now active on social media channels Rare and Autoinflammatory Diseases such as Facebook and Twitter, while maintaining the traditional website and the important personal physical presence at major rheumatology events. MENTOR MENTEE MEETINGS 17 If this is your first contact with EMEUNET, we invite you to explore more, and join us. If you are already EMEUNET NETWORKING EVENT 18 part of our community, we kindly remind you that sharing is caring. Spread the word about our activities EDUCATIONAL EVENTS 19 and work, and help us reach more young rheumatologists and researchers. COURSES 20 We hope you enjoy reading this Newsletter. We always welcome feedback, comments, suggestions, WORLD ARTHRITIS DAY 25 and contributions. We wish you a prolific and successful ACR 2017. BE PART OF THE EMEUNET COMMUNITY 26 See you in San Diego! Gonçalo Boleto and Richard Conway, on behalf of the Newsletter Subgroup

More information about EMEUNET can be found at http://emeunet.eular.org You can also reach us through the following email [email protected]

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OCTOBER 2017 2 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

BASIC RESEARCH I Genetics, cartilage/synovium, osteoimmunology, animal models

Andreas Ramming

Andreas is a rheumatology resident and research group leader at the University Hospital of Erlangen, Germany. He Hilfslinien anzeigen über Menu: focuses on translational research and especially signaling pathways in chronic inflammatory arthritis and fibrotic diseases. He is member of the EULAR education team, participating in authoring the EULAR Online Course on

Folie in Ursprungsform Systemic Sclerosis. Andreas is a member of the EMEUNET Education Subgroup.

Type, n° Date, time Session Room Author Title Wechsel der Textebene/Formatierungen Start FUNCTIONALLY DISTINCT PATHOGENIC Sunday SUBSETS OF FIBROBLASTS EXIST Oral Croft AP WITHIN THE INFLAMED SYNOVIAL 05.11.2017 32 B 863 – Animal Models (UK) MEMBRANE AND MEDIATE SPECIFIC 15:00 ASPECTS OF INFLAMMATORY DISEASE PATHOLOGY

INTERFERON-ALPHA OVEREXPRESSION Sunday Oral Rheumatoid Arthritis Decker P TRIGGERS AN EXPANSION OF HIGHLY 05.11.2017 32 B SUPPRESSIVE REGULATORY T – Animal Models (France) 866 15:45 LYMPHOCYTES PROTECTING AGAINST EXPERIMENTAL ARTHRITIS

PERSISTENCE OF MAST CELL-RICH Rheumatoid Arthritis Monday SYNOVITIS IS ASSOCIATED WITH LACK Poster – Human Etiology Rivellese F OF RESPONSE TO SYNTHETIC DISEASE 06.11.2017 Poster Hall C 1401 and Pathogenesis (UK) MODIFYING ANTI-RHEUMATIC DRUGS IN 9:00 Poster II PATIENTS WITH EARLY RHEUMATOID ARTHRITIS

HIGHER EXPRESSION OF TYPE 1 INTERFERON IN SYNOVITIS OF PATIENT Rheumatoid Arthritis Monday WITH UNDIFFERENTIATED ARTHRITIS Poster – Human Etiology Cuervo A BEFORE THEY MET RHEUMATOID 06.11.2017 Poster Hall C 1416 and Pathogenesis (Spain) ARTHRITIS CRITERIA COMPARED TO 9:00 Poster II ESTABLISHED RHEUMATOID ARTHRITIS. A RETROSPECTIVE STUDY WITH 14 YEARS OF FOLLOW-UP

Rheumatoid Arthritis – Small Molecules, Biologics and Gene Monday SYNERGISTIC REVERSAL OF ARTHRITIS Poster Therapy Poster II: Secchi C 06.11.2017 Poster Hall C BY SYNOVIOCYTE-TARGETED THERAPY Prognostic Factors, (USA) 1456 9:00 AND TNF IMMUNOMODULATION Imaging and Miscellaneous Reports

Rheumatoid Arthritis Tuesday Oral – Clinical Aspects V: Orr C THE UTILITY AND LIMITATIONS OF 07.11.2017 20 A SERUM C-REACTIVE PROTEIN IN Predicting Treatment (Ireland) 2865 17:30 APPRAISING SYNOVIAL INFLAMMATION Response

OCTOBER 2017 3 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

BASIC RESEARCH II Immunity, immunology

Mary Canavan

Mary is a postdoctoral researcher in molecular rheumatology in Trinity College Dublin. She completed her PhD in Hilfslinien anzeigen über Menu: Immunology in Dublin City University and is now completing her second postdoctoral research fellowship. Her research interests include examining immune infiltration, in particular dendritic cells and T cells in inflammatory

Folie in Ursprungsform arthritis, and examining the effects of the joint microenvironment on immune cell activation. Mary is co-leader of the EMEUNET Social Media Subgroup and leader of the ARD-EMEUNET social media collaboration.

Wechsel der Textebene/Formatierungen Type, n° Date, time Session Room Author Title Start

B cell Biology and Sunday SINGLE CELL ANALYSIS REVEALS Oral Targets in Hamilton J HETEROGENEITY OF TYPE I IFN GENE 05.11.2017 24 A 832 Autoimmune (USA) EXPRESSION IN DEVELOPING 14:45 Disease AUTOREACTIVE B CELLS

T cell Biology and MICRORNA21 IS A CRITICAL REGULATOR Sunday Oral Targets in Shen N OF AUTOIMMUNITY THROUGH 05.11.2017 33 C PROMOTING EFFECTOR AND Autoimmune (China) 954 17:45 METABOLIC FUNCTION OF PATHOGENIC Disease TH17 CELLS

Cytokines and Cell IL-7 IN PRIMARY SJOGREN SYNDROME Monday Trafficking: Oral Virone A (pSS) IS SECRETED BY SALIVARY GLAND 06.11.2017 Unexpected 23 A EPITHELIAL CELLS AFTER IFN (France) 1795 15:45 Effects of Known STIMULATION AND IS ASSOCIATED WITH Molecules ACTIVATION

Cytokines and Cell Tuesday Trafficking: Oral Karouzakis E TET1 IS AN IMPORTANT 06.11.2017 Unexpected 23 A TRANSCRIPTIONAL ACTIVATOR OF THE 1791 (Switzerland) 14:45 Effects of Known TNFA LOCUS IN MACROPHAGES Molecules

Tuesday Innate Immunity & SEVERE JUVENILE ARTHRITIS Oral Sikora KA ASSOCIATED WITH A DE NOVO GAIN-OF- 07.11.2017 Rheumatic 29 D 2773 (USA) FUNCTION GERMLINE MUTATION IN 15:00 Disease MYD88

Tuesday Innate Immunity & Oral Le Joncour A CRITICAL ROLE OF NEUTROPHIL 07.11.2017 Rheumatic 29 D EXTRACELLULAR TRAPS (NETS) IN 2775 (France) 15:30 Disease PATIENTS WITH BEHCET’S DISEASE

OCTOBER 2017 4 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

RA I Epidemiology, clinics and non biologics

Giulio Cavalli

Giulio is an attending physician and research fellow in the Unit of Immunology, Rheumatology, Allergy and Rare Hilfslinien anzeigen über Menu: Diseases at San Raffaele Hospital and University of Milan, Italy. His major research interests include inflammation, the Interleukin-1 family of molecules, and the genetic risk of developing autoimmunity. He is completing a PhD in inflammation at Radboud University in Njimegen, The Netherlands. Giulio is a member of the EMEUNET Social Media Folie in Ursprungsform Subgroup.

Type, n° Date, time Session Room Author Title Wechsel der Textebene/Formatierungen Start TEMPORARY DISCONTINUATION FOR 2 WEEKS Sunday Oral Park JK IMPROVES IMMUNOGENICITY OF 05.11.2017 Plenary Session I Hall B1 SEASONAL INFLUENZA VACCINATION IN 827 (South Korea) PATIENTS WITH RHEUMATOID 11:30 ARTHRITIS: A RANDOMIZED CLINICAL TRIAL

Rheumatoid Arthritis – Clinical Monday Aspects Poster II: IS DEPRESSION IN PATIENTS WITH Poster Morf H RHEUMATOID ARTHRITIS ASSOCIATED 06.11.2017 Pathophysiology, Poster Hall C 1340 (Germany) WITH DISEASE ACTIVITY? COMPARATIVE 9:00 Autoantibodies, and STUDY BETWEEN GERMANY AND BRAZIL Disease Activity Measures

Rheumatoid Arthritis – Clinical Monday Aspects Poster II: IMPACT OF FIBROMYALGIC RA ON Poster Hammer HB COMPOSITE SCORES; RESULTS FROM A 06.11.2017 Pathophysiology, Poster Hall C 1344 (Norway) LONGITUDINAL STUDY OF RA PATIENTS 9:00 Autoantibodies, and INITIATING BDMARD THERAPY Disease Activity Measures

Rheumatoid Arthritis – Clinical Monday Aspects Poster II: SIGNATURE Poster Kim H GENES AND CXCL10 AS NEW 06.11.2017 Pathophysiology, Poster Hall C 1369 (South Korea) BIOMARKERS IN EARLY STAGE OF 9:00 Autoantibodies, and RHEUMATOID ARTHRITIS Disease Activity Measures

Rheumatoid Arthritis – Clinical Monday Aspects Poster II: SERUM PROGRANULIN Poster Assman G (PGRN-ABS) IN RHEUMATOID ARTHRITIS 06.11.2017 Pathophysiology, (Germany) PATIENTS BEING NEGATIVE FOR RF-IGM 1389 Poster Hall C 9:00 Autoantibodies, and AND ACCP-IGG Disease Activity Measures

BRAIN FUNCTIONAL CONNECTIVITY Tuesday Oral Basu N FEATURES OF PAIN CENTRALISATION 07.11.2017 Plenary Session III Hall B1 RELATE TO DEGREE OF 2753 (UK) ‘FIBROMYALGIANESS’ IN RHEUMATOID 11:00 ARTHRITIS

OCTOBER 2017 5 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

RA II Biological therapies: anti-TNF

Meghna Jani

Meghna is an NIHR academic clinical lecturer and rheumatology trainee at the Arthritis Research UK Centre for Hilfslinien anzeigen über Menu: Epidemiology, University of Manchester, UK. Her research interests are in inflammatory arthritis (rheumatoid arthritis and psoriatic arthritis), pharmacoepidemiology, clinical epidemiology, immunogenicity to biologics, and stratified

Folie in Ursprungsform medicine. Meghna is the leader of the EMEUNET Education Subgroup and a social media editor for Annals of the Rheumatic Diseases.

Wechsel der Textebene/Formatierungen Start Type, n° Date, time Session Room Author Title MULTI-BIOMARKER DISEASE ACTIVITY Sunday Rheumatoid AND AUTOANTIBODY STATUS LEAD TO Poster Hagen M COST EFFECTIVE TAPERING 05.11.2017 Arthritis – Clinical Poster Hall C 414 (Germany) ALGORITHMS IN RHEUMATOID 9:00 Aspects Poster I ARTHRITIS PATIENTS IN SUSTAINED REMISSION

RHEUMATOID ARTHRITIS PATIENT Sunday Rheumatoid Poster Pappas DA CHARACTERISTICS ALSO PREDICT 05.11.2017 Arthritis – Clinical Poster Hall C RESPONSE TO THERAPY WITH (USA) 475 9:00 Aspects Poster I BIOLOGIC AGENTS: RESULTS FROM THE CORRONA CERTAIN STUDY

Rheumatoid LONG-TERM RISK OF SERIOUS Arthritis – Small INFECTIONS IN PATIENTS WITH Sunday Poster molecules, De Cock D RHEUMATOID ARTHRITIS TREATED 05.11.2017 Poster Hall C WITH RITUXIMAB: 5 YEAR DATA FROM 547 Biologics and (UK) 9:00 THE BRITISH SOCIETY FOR Gene therapy RHEUMATOLOGY BIOLOGICS REGISTER Poster I FOR RHEUMATOID ARTHRITIS

Kay J Great Sunday (USA) BIOSIMILARS… TO SWITCH OR NOT TO debate 05.11.2017 ACR session Hall B1 SWITCH? THAT IS THE QUESTION 3S081 14:30 Fleischmann R (USA)

SERIOUS OR OPPORTUNISTIC Monday Oral Chambers CD INFECTIONS IN INFANTS BORN TO 06.11.2017 Plenary Session II Hall B1 PREGNANT WOMEN WITH RHEUMATOID (USA) 1785 11:15 ARTHRITIS AND TREATED WITH A BIOLOGIC MEDICATION

Rheumatoid COMPARATIVE EFFECTIVENESS OF Arthritis – Small (TCZ) MONOTHERAPY Tuesday Poster molecules, Harrold LR WITH 07.11.2017 Poster Hall C INHIBITORS (TNFI) IN COMBINATION 2449 Biologics and (USA) 9:00 WITH VARYING DOSES OF Gene therapy METHOTREXATE (MTX) IN PATIENTS Poster III WITH RHEUMATOID ARTHRITIS

SUSTAINED REMISSION OF Spondyloarthropat Tuesday INFLAMMATION IS ASSOCIATED WITH Oral hies & Psoriatic Maksymowych WP REDUCED STRUCTURAL DAMAGE ON SI 07.11.2017 6 D 2802 Arthritis – Clinical (Canada) JOINT MRI IN PATIENTS WITH EARLY 14:45 & Treatment III AXIAL SPA: EVIDENCE TO SUPPORT THE CONCEPT OF TREAT-TO-TARGET

OCTOBER 2017 6 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

RA III Other biologics and new drugs beyond biologics

Jan Leipe

Jan is a board-certified rheumatologist and is currently an attending physician at the University of Munich, Germany. Hilfslinien anzeigen über Menu: His major research interests include early rheumatoid arthritis and the role of T cells in the pathogenesis of autoimmune arthritis. Jan is a member of the EMEUNET Peer-mentoring Subgroup.

Folie in Ursprungsform

Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen Start Rheumatoid Arthritis – Small Molecules, INADEQUATE CLINICAL RESPONSE TO Biologics and Gene Monday SIRUKUMAB, AN ANTI-IL-6 MONOCLONAL Poster Therapy Poster II: Poster Hall C Daga S 06.11.2017 , CAN BE PREDICTED AFTER A 1478 Prognostic Factors, 09:00 (UK) SINGLE DOSE OF TREATMENT IN Imaging and PATIENTS WITH RHEUMATOID ARTHRITIS Miscellaneous Reports

DOSE REDUCTION OF IN RA–SM Molecules, Monday PATIENTS WITH RHEUMATOID ARTHRITIS Oral Biologics & Gene 6 C Takeuchi T 06.11.2017 ACHIEVING SUSTAINED DISEASE 1821 Therapy I: Outcomes (Japan) 14:45 CONTROL: RESULTS OF A PROSPECTIVE Therapy STUDY

DEVELOPMENT OF - AND Monday, Rheumatoid arthritis -SPECIFIC PREDICTIVE Oral 20 A Connolly SE 06.11.2017 – Clinical Aspects II: MODELS OF RESPONSE TO THERAPY IN 1818 (USA) 15:30 Treatment Patterns RA USING DATA FROM A HEAD-TO-HEAD STUDY

A PHASE 3 RANDOMIZED, PLACEBO- CONTROLLED, DOUBLE-BLIND STUDY OF RA–SM Molecules, Monday (ABT-494), A SELECTIVE Oral Biologics & Gene Hall B1 Burmester GR 06.11.2017 JAK-1 INHIBITOR, IN PATIENTS WITH 1904 Therapy II: Trials (Germany) 16:30 ACTIVE RHEUMATOID ARTHRITIS WITH Therapy INADEQUATE RESPONSE TO CONVENTIONAL SYNTHETIC DMARDS

SAFETY, PHARMACOKINETICS, AND RA–SM Molecules, EFFICACY OF E6011, AN ANTI- Monday Oral Biologics & Gene Hall B1 Tanaka Y FRACTALKINE MONOCLONAL ANTIBODY, 06.11.2017 1907 Therapy II: Trials (Japan) IN A FIRST-IN-PATIENT PHASE 1/2 STUDY 17:15 Therapy ON RHEUMATOID ARTHRITIS: 52-WEEK RESULTS

RA–SM Molecules, Biologics and Gene COMPARATIVE EFFECTIVENESS OF Tuesday Therapy Poster III: Poster Harrold LR ABATACEPT VERSUS TNFI IN PATIENTS 07.11.2017 Efficacy and Safety Poster Hall C 2450 (USA) WITH RA WHO ARE CCP+ IN THE UNITED 09:00 of Originator STATES CORRONA REGISTRY Biologics and Biosimilars

COMPARATIVE RISK OF BIOLOGIC Tuesday, Oral George MD THERAPIES IN PATIENTS WITH 07.11.2017 Plenary Session III Hall B1 2755 (USA) RHEUMATOID ARTHRITIS UNDERGOING 11:30 ELECTIVE ARTHROPLASTY

OCTOBER 2017 7 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

PSORIATIC ARTHRITIS

Marie Kostine

Marie is an assistant professor in the rheumatology department at Bordeaux Hospital, France. Her major clinical and Hilfslinien anzeigen über Menu: research interest is in onco-rheumatology, with regard to rheumatic manifestations occurring in cancer patients. She is completing a PhD in immune infiltrate in bone and soft-tissue sarcomas, and spent 2 years at the Leiden University

Folie in Ursprungsform Medical Center, Netherlands. Marie is the co-leader of the EMEUNET Global Affairs Subgroup.

Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen TREATMENT IN PATIENTS Start Sunday SpA and PsA – WITH PSORIATIC ARTHRITIS AND RATES Oral van der Heijde D OF RADIOLOGIC PROGRESSION 05.11.2017 Clinical Aspects 6 D 880 (Netherlands) ACCORDING TO BASELINE CRP LEVELS: 14:45 and Treatment I RESULTS FROM A PHASE 3 CLINICAL STUDY

USTEKINUMAB IS SUPERIOR TO TNF Sunday SpA and PsA – INHIBITOR TREATMENT IN RESOLVING Oral Araujo EG ENTHESITIS IN PSA PATIENTS WITH 05.11.2017 Clinical Aspects 6 D 881 (Germany) ACTIVE ENTHESITIS-RESULTS FROM THE 15:00 and Treatment I ENTHESIAL CLEARANCE IN PSORIATIC ARTHRITIS STUDY

BROAD IMMUNOPHENOTYPING RESULTS: Monday SpA and PsA – Oral Leijten EFA CCR10 EXPRESSING CD8 T CELLS 06.11.2017 Pathogenesis, 9 DISTINGUISH PSORIATIC ARTHRITIS FROM (Netherlands) 1912 17:00 Etiology PSORIASIS LIMITED TO SKIN INVOLVEMENT

SpA and PsA – Tuesday Poster Clinical Aspects Szeto VG DO PSORIATIC DISEASE PATIENTS WHO 07.11.2017 Poster Hall C PARTICIPATE IN CLINICAL RESEARCH and Treatment (Canada) 2557 9:00 DIFFER FROM THOSE WHO DO NOT ? Poster III

SpA and PsA – Tuesday PREVALENCE OF CARDIOVASCULAR RISK Oral Clinical Aspects Martinez-Vidal MP FACTORS AND SUBCLINICAL 07.11.2017 6 A 2883 and Treatment (Spain) CARDIOVASCULAR DISEASE IN PSORIATIC 17:45 IV ARTHRTIS

EFFICACY AND SAFETY OF IXEKIZUMAB IN Wednesday SpA and PsA – Oral Genovese MC PATIENTS WITH ACTIVE PSORIATC 08.11.2017 Clinical Aspects 28 A-E ARTHRITIS AND PREVIOUS INADEQUATE 2969 (USA) 11:15 and Treatment V RESPONSE TO TNF INHIBITORS: 52-WEEK RESULTS FROM A PHASE 3 STUDY

DETECTION OF CLINICAL SIGNS OF ARTHRITIS AND SUBCLINICAL EVIDENCE OF INFLAMMATION IN PSORIASIS Wednesday SpA and PsA – Oral Koehm M PATIENTS WITH RISK FOR ARTHRITIS: 08.11.2017 Clinical Aspects 28 A-E VALUE OF CLINICAL EXAMINATION, 2973 (Germany) 12:15 and Treatment V ULTRASOUND AND FLUORESCENCE- OPTIMAL IMAGING – RESULTS FROM THE PROSPECTIVE MULTICENTRE XCITING STUDY

OCTOBER 2017 8 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

AXIAL SPONDYLOARTHRITIS

Marloes van Onna

Marloes is a staff rheumatologist at the Maastricht University Medical Center, Maastricht, the Netherlands. She Hilfslinien anzeigen über Menu: completed her dissertation on early identification and referral of patients suspected of having axial spondyloarthritis. Her research focuses on spondyloarthritis, rheumatoid arthritis, and outcomes research. Marloes is a member of the EMEUNET Education Subgroup. Folie in Ursprungsform

Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen Start MORE THAN 10 PERCENT PATIENTS Monday SpA and PsA – Poster Molto A WITH RECENT ONSET CHRONIC 06.11.2017 Clinical Aspects and Poster Hall C MECHANICAL BACK PAIN FULFILL (France) 1504 09:00 Treatment Poster II THE MODIFIED NY CRITERIA FOR SACROILIITIS

Monday SpA and PsA – Poster Hall C SIMILARITIES AND DIFFERENCES Poster Poddubnyy D BETWEEN NON-RADIOGRAPHIC AND 06.11.2017 Clinical Aspects and 1509 (Germany) RADIOGRAPHIC AXIAL 09:00 Treatment Poster II SPONDYLOARTHRITIS

EFFICACY OF SWITCHING Monday SpA and PsA – Poster Hall C Poster Navarro-Compán V BIOLOGICAL DMARDS IN PATIENTS 06.11.2017 Clinical Aspects and WITH AXIAL SPONDYLOARTHRITIS: (Spain) 1533 09:00 Treatment Poster II RESULTS FROM A SYSTEMATIC LITERATURE REVIEW

A POSITIVE MRI OF THE Monday SpA and PsA – SACROILIAC JOINTS IS NOT Oral de Winter J SPECIFIC FOR AXIAL 06.11.2017 Clinical Aspects and 6 D 1831 (Netherlands) SPONDYLOARTHRITIS BUT 15:45 Treatment II FREQUENTLY OCCURS IN HEALTHY INDIVIDUALS

Monday SpA and PsA – Oral Debusschere K GUT-DERIVED TNF AS RISK FACTOR 06.11.2017 Pathogenesis, 9 FOR THE DEVELOPMENT OF 1915 (Belgium) 17:45 Etiology SACROILIAC INFLAMMATION

SpA and PsA – DEFINING CLINICALLY IMPORTANT Clinical Aspects and WORSENING BASED ON ASDAS-CRP Tuesday Poster Treatment Poster III: Molto A FOR AXIAL SPONDYLOARTHRITIS: A 07.11.2017 Poster Hall C DATA-BASED CONSENSUS BY THE 2502 Outcomes, Outcome (France) 09:00 ASSESSMENT IN Measures, and SPONDYLOARTHRITIS Comorbidities INTERNATIONAL SOCIETY (ASAS)

OCTOBER 2017 9 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

SLE & APS

Md Yuzaiful Md Yusof

Yuz is a NIHR funded doctoral research fellow and a specialist registrar in rheumatology at Leeds Teaching Hospitals

Hilfslinien anzeigen über Menu: NHS Trust. His major research interests include B cell therapies, systemic erythematosus (SLE), ANCA- associated vasculitis, infections, and biomarkers. He is completing a PhD in personalising biological therapies in at risk and established SLE at the University of Leeds. Yuz is a member of the EMEUNET Newsletter Subgroup. Folie in Ursprungsform Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen SLE – Clinical PHASE 3 TRIAL RESULTS WITH Start Sunday Aspects and BLISIBIMOD, A SELECTIVE INHIBITOR Oral Merrill JT OF B-CELL ACTIVATING FACTOR, IN 05.11.2017 Treatment I: Novel 20 D 888 (USA) SUBJECTS WITH MODERATE-TO- 15:15 and Current SEVERE SYSTEMIC LUPUS Therapies ERYTHEMATOSUS

SLE – Clinical Monday Aspects and LUPUS LOW DISEASE ACTIVITY Poster Petri M STATE: CAN WE RELAX THE 06.11.2017 Treatment Poster II: Poster Hall C 1603 (USA) DEFINITION AND STILL ACHIEVE LOW 09:00 Damage and RISK OF SLE-RELATED DAMAGE? Comorbidities

SLE – Clinical THE MONTREAL COGNITIVE Monday Aspects and Poster Chalhoub N ASSESSMENT QUESTIONNAIRE 06.11.2017 Treatment Poster II: Poster Hall C (MoCA): A PROMISING SCREENING (USA) 1650 09:00 Damage and TOOL FOR COGNITIVE DYSFUNCTION Comorbidities IN SLE

BLOOD LEVELS OF COMPLEMENT SLE – Clinical SPLIT PRODUCT iC3b AND C3 Monday Oral Aspects and Kim A OUTPERFORM TRADITIONAL 06.11.2017 6 A BIOCHEMICAL MEASURES OF SLE Treatment III: (USA) 1918 17:00 DISEASE ACTIVITY IN ASSOCIATING Biomarkers WITH ACTIVE AND CLINICALLY MEANINGFUL CHANGES

Tuesday ARHP SLE – Clinical Poster Friday R DOSECHECKER: SOLVING THE 07.11.2017 Aspects and Poster Hall C HYDROXYCHLOROQUINE DOSING 2635 (USA) 09:00 Treatment Poster DILEMMA WITH A SMART PHONE APP

Tuesday ADENOSINE AGONISM Oral Antiphospholipid Ali RA PROTECTS AGAINST ANTI- 07.11.2017 33 C 2761 Syndrome (USA) PHOSPHOLIPID ANTIBODY-MEDIATED 15:00 NETOSIS AND VENOUS THROMBOSIS

B CELL BINDING AUTOREACTIVE Wednesday SLE – Human VH4.34 ANTIBODIES ARE SPECIFIC TO Oral Jenks S LUPUS, CONSIST OF DIVERSE 08.11.2017 Etiology and 24 A 2974 (USA) ISOTYPES, AND ARE ASSOCIATED 11:00 Pathogenesis II WITH HIGH DISEASE ACTIVITY AND LUPUS NEPHRITIS

OCTOBER 2017 10 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

OTHER CONNECTIVE TISSUE DISEASES Including systemic sclerosis, myositis, vasculitis

Gonçalo Boleto

Gonçalo is a trainee in Rheumatology and Clinical Immunology in Reims University Hospital, France, and a research

Hilfslinien anzeigen über Menu: fellow within the Cochin Institut, Paris, France. His research focus on the pathophysiology of systemic sclerosis with a specific interest in experimental inflammation-driven fibrosis. He is a member of the Newsletter subgroup.

Folie in Ursprungsform Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen Systemic Sclerosis, Start Sunday Fibrosing Syndromes and Poster Frost DB A POSITIVE FEEDBACK LOOP 05.11.2017 Raynaud's – Pathogenesis, Poster Hall C BETWEEN ESTROGEN AND IL-6 768 (USA) 09:00 Animal Models and Genetics LEADS TO FIBROSIS IN HUMAN SKIN Poster I

LONG-TERM EFFICACY AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH REFRACTORY TAKAYASU Sunday ARTERITIS TREATED Oral Vasculitis I: Clinical Trials Nakaoka Y 05.11.2017 29 D CONTINUOUSLY OVER 52 WEEKS: and Outcomes (Japan) 891 14:30 RESULTS FROM PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL AND OPEN-LABEL EXTENSION IN JAPAN

Systemic Sclerosis, SIRT1 MAY PROTECT AGAINST Monday Fibrosing Syndromes and Poster Wang J SYSTEMIC SCLEROSIS-RELATED 06.11.2017 Raynaud's – Pathogenesis, Postel Hall C PULMONARY FIBROSIS BY (China) 1711 09:00 Animal Models and Genetics DECREASING PRO-INFLAMMATORY Poster II AND PRO-FIBROTIC PROCESSES

THE NOVEL ANTI-CD40 MONOCLONAL ANTIBODY CFZ533 Monday Oral Fisher B SHOWS BENEFICIAL EFFECTS IN 06.11.2017 Plenary Session II Hall B 1 PATIENTS WITH PRIMARY (UK) 1784 11:00 SJÖGREN’S SYNDROME: A PHASE IIA DOUBLE-BLIND, PLACEBO- CONTROLLED RANDOMIZED TRIAL

QUANTITATIVE NAILFOLD VIDEO Tuesday Poster Muscle Biology, Myositis and Rider LG CAPILLAROSCOPY PARAMETERS 07.11.2017 Poster Hall C CORRELATE WITH 2141 Myopathies Poster (USA) 09:00 DERMATOMYOSITIS ACTIVITY AND DAMAGE

Systemic Sclerosis, Tuesday TADALAFIL REDUCES SKIN Oral Fibrosing Syndromes and Ahmed S FIBROSIS AND PROFIBROTIC GENES 07.11.2017 33 C 2885 Raynaud's – Clinical Aspects (India) EXPRESSION IN PATIENTS WITH 16:45 and Therapeutics II SYSTEMIC SCLEROSIS

PREDICTORS FOR DISEASE Systemic Sclerosis, Wednesday WORSENING DEFINED BY ORGAN Oral Fibrosing Syndromes and Becker MO FAILURE IN DIFFUSE SYSTEMIC 08.11.2017 32 B Raynaud's – Clinical Aspects (Switzerland) SCLEROSIS: A EUROPEAN 2983 11:45 and Therapeutics III SCLERODERMA TRIALS AND RESEARCH (EUSTAR) ANALYSIS

OCTOBER 2017 11 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

IMAGING

Yesim Ozguler

Yesim is a third year rheumatology fellow at the department of internal medicine, division of rheumatology of the

Hilfslinien anzeigen über Menu: Istanbul University, Cerrahpasa Medical Faculty in Turkey. She has been EMEUNET Working Group member since 2015. She worked as fellow in the taskforce for the new EULAR recommendations for the management of Behçet’s disease. She has also been working as OMERACT fellow in Behçet’s disease special interest group since 2014. Her Folie in Ursprungsform main interests are Behcet’s syndrome and vasculitis.

Type, n° Date, time Session Room Author Title Wechsel der Textebene/Formatierungen Start Sunday Vasculitis Poster I: EUROPEAN LEAGUE AGAINST Poster Dejaco C RHEUMATISMS RECOMMENDATIONS FOR 05.11.2017 Large Vessel Poster Hall C 783 (Italy) THE USE OF IMAGING IN LARGE VESSEL 09:00 Vasculitis VASCULITIS IN CLINICAL PRACTICE

Sunday Genetics, Genomics MASS SPECTROMETRY IMAGING OF Poster Rocha B SYNOVIUM: A NOVEL APPROACH TO 05.11.2017 and Proteomics Poster Hall C 179 (Spain) CLASSIFY THE RHEUMATOID AND 09:00 Poster I PSORIATIC ARTHRITIS PATIENTS

PRESENCE OF BONE MARROW EDEMA Sunday Imaging of AND STRUCTURAL LESIONS ON Poster Renson T MAGNETIC RESONANCE IMAGING OF THE 05.11.2017 Rheumatic Diseases Poster Hall C 253 (Belgium) SACROILIAC JOINTS IN YOUNG MILITARY 09:00 Poster I RECRUITS BEFORE AND AFTER 6 WEEKS OF INTENSIVE PHYSICAL TRAINING

THE USE OF POSITRON EMISSION Sunday Imaging of Poster Voskuyl A TOMOGRAPHY (PET)-SCAN FOR THE 05.11.2017 Rheumatic Diseases Poster Hall C QUANTITATIVE ASSESSMENT OF 257 (Netherlands) 09:00 Poster I INTERSTITIAL LUNG DISEASE IN SYSTEMIC SCLEROSIS

DEFINITION AND STANDARDIZATION OF INFLAMMATORY PATHOLOGY IN HAND Tuesday Imaging of Poster Mathiessen A OSTEOARTHRITIS ASSESSED BY 07.11.2017 Rheumatic Diseases Poster Hall C ULTRASOUND: RESULTS FROM A DELPHI 2020 (Norway) 09:00 Poster II PROCESS AND RELIABILITY TESTING IN THE OMERACT ULTRASONOGRAPHER GROUP IN HAND OSTEOARTHRITIS

Tuesday Imaging of NAILFOLD CAPILLAROSCOPY IN Poster Dinsdale G SYSTEMIC SCLEROSIS: HOW MANY 07.11.2017 Rheumatic Diseases Poster Hall C 2005 (UK) FINGERS SHOULD BE EXAMINED TO 09:00 Poster II DETECT ABNORMALITY?

DETECTION OF CLINICAL SIGNS OF ARTHRITIS AND SUBCLINICAL EVIDENCE OF INFLAMMATION IN PSORIASIS SpA and PsA – PATIENTS WITH RISK FOR ARTHRITIS: Oral Wednesday Koehm M Clinical Aspects and 28 A-E VALUE OF CLINICAL EXAMINATION, 2973 08.11.2017 (Germany) Treatment V ULTRASOUND AND FLUORESCENCE- 12:15 OPTICAL IMAGING – RESULTS FROM THE PROSPECTIVE MULTICENTRE XCITING STUDY

OCTOBER 2017 12 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

OSTEOARTHRITIS & OSTEOPOROSIS

Francesca Ometto

Francesca is a rheumatologist since 2014. She is currently a PhD candidate at the University Hospital of Padova, Italy. Hilfslinien anzeigen über Menu: Her major research interests include inflammatory arthritides, biological drugs and patient reported outcomes.

Folie in Ursprungsform Type, n° Date, time Session Room Author Title

EFFECTIVENESS OF FX006 INTRA- ARTICULAR INJECTION IN PATIENTS WITH Wechsel der Textebene/Formatierungen Start Sunday Osteoarthritis Clinical KNEE OSTEOARTHRITIS WHO PRESENT Oral Baraf HSB WITH AND WITHOUT CLINICAL 05.11.2017 Aspects I: Pain and 31 C 934 (USA) INFLAMMATION AT BASELINE: A POOLED 17:15 Functional Outcomes ANALYSIS OF DATA FROM 3 DOUBLE- BLIND, RANDOMIZED, PARALLEL-GROUP CLINICAL TRIALS

RESULTS FROM A 52 WEEK Sunday Osteoarthritis Clinical RANDOMIZED, DOUBLE-BLIND, PLACEBO- Oral Yazici Y CONTROLLED, PHASE 2 STUDY OF A 05.11.2017 Aspects I: Pain and 31 C 935 (USA) NOVEL, INTRA- ARTICULAR, WNT 17:30 Functional Outcomes PATHWAY INHIBITOR (SM04690) FOR THE TREATMENT OF KNEE OSTEOARTHRITIS

Osteoporosis and Metabolic ASSOCIATIONS BETWEEN MUSCLE MASS Monday Poster Bone Disease – Clinical Lobo D AND FUNCTION WITH BONE 06.11.2017 Poster Hall C MICROARCHITECTURE AND BONE 1219 Aspects and Pathogenesis (Brazil) 09:00 STRENGTH IN POSTMENOPAUSAL Poster II WOMEN

CONTINUED FRACTURE RISK REDUCTION AFTER 12 MONTHS OF ROMOSOZUMAB Monday Osteoporosis and Metabolic Oral Lewiecki EM FOLLOWED BY DENOSUMAB THROUGH 06.11.2017 Bone Disease – Clinical 32 B 36 MONTHS IN THE EXTENSION OF THE 1886 (USA) 16:30 Aspects and Pathogenesis PHASE 3 FRACTURE STUDY IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS

ASSOCIATION BETWEEN Osteoarthritis – Clinical Tuesday MITOCHONDRIAL DNA (MTDNA) Poster Aspects Poster II: Rego-Pérez I HAPLOGROUPS AND BONE MARROW 07.11.2017 Poster Hall C 2192 Observational and (Spain) LESIONS AT 24 MONTHS IN 09:00 Epidemiological Studies OSTEOARTHRITIS SUBJECTS: SUBJETS FROM THE OSTEOARTHRITIS INITIATIVE

Osteoarthritis – Clinical Tuesday LEPTIN AND ADIPONECTIN MEDIATE THE Poster Aspects Poster II: Kroon FPB ASSOCIATION BETWEEN BODY MASS 07.11.2017 Poster Hall C 2209 Observational and (Netherlands) INDEX AND HAND AND KNEE 09:00 Epidemiological Studies OSTEOARTHRITIS

Session Title: Osteoarthritis Wednesday INCIDENT HAND OA IS STRONGLY Oral – Clinical Aspects II: McAlindon TE ASSOCIATED WITH REDUCED 08.11.2017 10 2945 Structural Progression and (USA) PERIPHERAL BLOOD LEUKOCYTE 11:15 Incidence TELOMERE LENGTH

Session Title: Osteoarthritis DO BONE MARROW LESIONS Wednesday Oral – Clinical Aspects II: Deveza L REACTIVATE ENDOCHONDRAL 08.11.2017 10 OSSIFICATION LEADING TO OSTEOPHYTE 2947 Structural Progression and (Australia) 11:45 GENESIS? DATA FROM THE Incidence OSTEOARTHRITIS INITIATIVE

OCTOBER 2017 13 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

METABOLIC & CRYSTAL ARTHROPATHIES

Paul Studenic

Paul is a clinical fellow in internal medicine and rheumatology, and research associate at the Medical University of Hilfslinien anzeigen über Menu: Vienna in the Division of Rheumatology. He is in the final phase of his PhD, that he is conducting under the supervision of Prof. Daniel Aletaha and has a major research focus on outcome measures and disease assessment in inflammatory arthritis, particularly patient reported outcomes and biomarkers as well as observational longitudinal and Folie in Ursprungsform reliability studies. Paul is the co-leader of the EMEUNET Social Media Subgroup.

Wechsel der Textebene/Formatierungen Start Type, n° Date, time Session Room Author Title

Monday Poster Metabolic and Crystal Merriman TR A GENOME-WIDE ASSOCIATION 06.11.2017 Poster Hall C STUDY OF GOUT IN PEOPLE OF 1104 Arthropathies Poster I (New Zealand) 09:00 EUROPEAN ANCESTRY

PROTECTIVE EFFECT OF Monday Poster Metabolic and Crystal Vargas-Santos AB ALLOPURINOL USE ON KIDNEY 06.11.2017 Poster Hall C FUNCTION AMONG PATIENTS WITH Arthropathies Poster I (Brazil) 1111 09:00 GOUT AND CHRONIC KIDNEY DISEASE

Osteoporosis and TEN-YEAR CONTINUED Monday Metabolic Bone Oral Kendler DL NONVERTEBRAL FRACTURE 06.11.2017 Disease – Clinical 32 B REDUCTION IN POSTMENOPAUSAL 1887 (Canada) 16:45 Aspects and OSTEOPOROSIS WITH DENOSUMAB Pathogenesis TREATMENT

COMPUTED TOMOGRAPHY DEPEDENT DIAGNOSIS OF Tuesday Poster Metabolic and Crystal Haikal A CROWNED DENS SYNDROME: A 07.11.2017 Poster Hall C CERVICAL MANIFESTATION OF 2053 Arthropathies Poster II (USA) 09:00 PATIENTS WITH CALCIUM PYROPHOSPHATE DIHYDRATE CRYSTAL DEPOSITION DISEASE

Tuesday Poster Metabolic and Crystal Kim IY CLINICAL SIGNIFICANCE OF URATE 07.11.2017 Poster Hall C DEPOSITION IN TENDON: A DUAL- 2088 Arthropathies Poster II (South Korea) 09:00 ENERGY CT STUDY

Metabolic and Crystal Arthropathies I: Gout THE SONS OF GOUT STUDY. Tuesday Oral Risk of Disease Abhishek A ULTRASONOGRAPHIC EVALUATION 07.11.2017 28 A-E OF ASYMPTOMATIC MONOSODIUM Activity, (United Kingdom) 2847 17:30 URATE CRYSTAL DEPOSITION IN Cardiovascular SONS OF PEOPLE WITH GOUT Disease and Mortality

Metabolic and Crystal Wednesday Arthropathies II: TRAPPED CRYSTALS IN SYNOVIAL Oral Gonzalez EG FLUID: NEUTROPHIL 08.11.2017 Mechanisms of Crystal 32 B 2899 (Italy) EXTRACELLULAR TRAPS (NETS) 09:45 Inflammation and FROM BENCH TO BED-SIDE Metabolism

OCTOBER 2017 14 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

PAEDIATRIC RHEUMATOLOGY

Mike Becker

Mike is a consultant rheumatologist and researcher at the University Hospital of Zürich, Switzerland. His research

Hilfslinien anzeigen über Menu: focuses on clinical and translational aspects of systemic sclerosis and his major clinical interests include connective tissue diseases and vasculitis. He graduated from the Philipps University in Marburg, Germany and got a Master`s degree from the University of Oxford, UK. Mike is a member of the EMEUNET Newsletter Subgroup. Folie in Ursprungsform Type, n° Date, time Session Room Author Title

Wechsel der Textebene/Formatierungen STIMULATOR OF INTERFERON Start GENES (STING)-INDUCED Pediatric Sunday ENDOTHELIAL-MESENCHYMAL Oral Rheumatology – Almeida de Jesus A TRANSITION (ENDMT) 05.11.2017 32 B 939 Pathogenesis and (USA) CONTRIBUTES TO INTERSTITIAL 17:00 Genetics LUNG DISEASE IN STING- ASSOCIATED VASCULOPATHY WITH ONSET IN INFANCY (SAVI) PATIENTS

Pediatric IL1RN VARIATION IS ASSOCIATED Oral Rheumatology – Ombrello MJ WITH SYSTEMIC JUVENILE Sunday 32 B IDIOPATHIC ARTHRITIS AND Pathogenesis and (USA) 940 05.11.2017 PREDICTS NON-RESPONSE TO Genetics 17:15 TREATMENT

SERUM INTERLEUKIN 18 AS A Pediatric BIOMARKER FOR SYSTEMIC Rheumatology – Monday JUVENILE IDIOPATHIC ARTHRITIS Oral Clinical and Yasin S AND MACROPHAGE ACTIVATION 06.11.2017 29 D 1895 Therapeutic Aspects I: (USA) SYNDROME AND USE OF 17:15 Autoinflammatory RECOMBINANT HUMAN IL-18 BP IN A Diseases PATIENT WITH REFRACTORY DISEASE

Pediatric Rheumatology – Tuesday METHOTREXATE AS FIRST LINE Poster Clinical and Zulian F THERAPY IN JUVENILE IDIOPATHIC 07:11:2017 Poster Hall C 2295 Therapeutic Aspects (Italy) ARTHRITIS-ASSOCIATED UVEITIS: 09:00 Poster III: Juvenile MYTH OR REALITY Arthritis

Pediatric QUANTITATIVE PROTEOMICS Tuesday Angeles-Han S Poster Rheumatology – COMPARISON OF CHILDREN WITH 07.11.2017 Poster Hall C INACTIVE AND ACTIVE UVEITIS 2322 Pathogenesis and 09:00 (USA) Genetics Poster

Pediatric Tuesday Rheumatology – SHORT AND LONG-TERM FOLLOW- Oral Vegas-Revenga N UP OF TOCILIZUMAB FOR SEVERE 07.11.2017 Clinical and 29 D 2857 (Spain) JUVENILE IDIOPATHIC ARTHRITIS- 17:00 Therapeutic Aspects II: ASSOCIATED UVEITIS Juvenile Arthritis

Pediatric EVIDENCE BASED Rheumatology – RECOMMENDATIONS FOR Wednesday Clinical and Oral Ruperto N CORTICOSTEROID 08.11.2017 Therapeutic Aspects 25 A TAPERING/DISCONTINUATION IN (Italy) 2956 11:00 III: Lupus, NEW ONSET JUVENILE Dermatomyositis, and DERMATOMYOSITIS PATIENTS FROM THE PRINTO TRIAL Scleroderma

OCTOBER 2017 15 ORAL PRESENTATIONS & POSTERS ACR 2017 SAN DIEGO

RARE AND AUTOINFLAMMATORY DISEASES

Anne Troldborg

Anne is a rheumatology fellow and researcher at the University of Aarhus, Denmark. She recently defended her PhD in Hilfslinien anzeigen über Menu: innate immunity and SLE. Fields of interest include immunology, the complement system, SLE, and CTDs. She takes part in the evaluation and improvement of rheumatology departments in Denmark, and is responsible for training specialists in rheumatology led by the Ministry of Health. Anne is a member of the EMEUNET Education and Visibility Folie in Ursprungsform Subgroups.

Wechsel der Textebene/Formatierungen Start Type, n° Date, time Session Room Author Title

Miscellaneous Monday THE UTILITY OF AUTOIMMUNE Oral Rheumatic and Wu A 06.11.2017 31 C SEROLOGIES IN RECURRENT AND 1881 Inflammatory (USA) 16:45 CHRONIC INFLAMMATORY EYE DISEASE Diseases I

Miscellaneous Monday Mehta BY Oral Rheumatic and EPIDEMIOLOGY OF HOSPITALIZED 06.11.2017 31 C (USA) ADULT ONSET STILL’S DISEASE IN 1885 Inflammatory 17:45 UNITED STATES Diseases I

Miscellaneous Tuesday Poster Rheumatic and Lee SJ ASSOCIATION OF RETROPERITONEAL 07.11.2017 Poster Hall C 2122 Inflammatory (South Korea) FIBROSIS WITH MALIGNANCY 09:00 Diseases poster II

INFECTION IS THE MAJOR TRIGGER OF Tuesday ADULT HEMOPHAGOCYTIC SYNDROME, Oral Retamozo S 07.11.2017 Infection-related AN ORPHAN SYSTEMIC 2841 32 B (Spain) 17:30 Rheumatic Disease HYPERINFLAMMATORY, LIFE- THREATENING DISEASE: ANALYSIS IN 147 PATIENTS (GEAS-SEMI REGISTRY)

Miscellaneous Wednesday INFLAMMATORY ARTHRITIS DUE TO Oral Rheumatic and Cappelli L IMMUNE CHECKPOINT INHIBITORS: A 08.11.2017 33 C 2902 Inflammatory (USA) PERSISTENT PROBLEM REQUIRING 09:00 Diseases II IMMUNOSUPPRESSION

Miscellaneous Wednesday SALIVARY GLAND ENLARGEMENT IN Oral Rheumatic and Nares EM IGG4-RELATED DISEASE IS ASSOCIATED 08.11.2017 33 C 2907 Inflammatory (Mexico) WITH MULTIORGAN INVOLVEMENT AND 10:15 Diseases II HIGHER BASAL DISEASE ACTIVITY

OCTOBER 2017 16 MENTOR MENTEE MEETINGS

MENTOR MENTEE MEETINGS AT ACR 2017

Would you like the opportunity to discuss your research and future career with a leader in the field in a friendly and informal way? Then sign up for the mentor-mentee meetings at ACR 2017!

The meetings will last approximately 60 minutes. There won't be any formal presentations at Hilfslinien anzeigen über Menu: this meeting and it is only organized to give you a chance to have a chat with leaders in your area of research and discuss your career plans. The number of mentees will be 4-6 for each group. Click here to view an explanatory video with feedback from mentees and mentors. Folie in Ursprungsform

These meetings will be held on Tuesday, November 7th from 09:00 to 10:00 am. The meeting Wechsel der Textebene/Formatierungen place information will be announced later. Start

This year we introduced a change to give you the opportunity to see a different perspective we have also invited a mentor from the United States.

Prof. Tom Huizinga Assoc. Prof. Yusuf Yazici Assoc. Prof. Xenofon Baraliakos

Prof. Tom Huizinga (Leiden University Medical Center / Netherlands): Translational research in rheumatoid arthritis, clinical research in neuro-psychiatric SLE.

Assoc. Prof. Yusuf Yazici (New York University School of Medicine / United States): Rheumatoid arthritis, early arthritis; patient-reported outcomes, database and registry management and Behcet’s syndrome.

Assoc. Prof. Xenofon Baraliakos (Ruhr-University Bochum / Germany): Axial spondyloarthritis, especially on the description of the disease processes, its natural course, the efficacy and safety of therapeutic interventions and on the imaging of the disease.

If you want to attend any of these sessions, please send an email with your name, position, institute, who you want to meet and why, to: [email protected] , [email protected], and [email protected] . Please keep in mind that the number of places available is limited and we will close the groups when the target number is reached.

OCTOBER 2017 17 EMEUNET NETWORKING EVENT

EMEUNET NETWORKING EVENT AT ACR 2017

EMEUNET MEET UP at ACR San Diego 2017 Sunday November 5th 2017 6pm PDT Hilfslinien anzeigen über Menu: We are thrilled to invite you to the EMEUNET networking event in Folie in Ursprungsform San Diego on Sunday evening (November 5th). We are planning an evening of food, drinks and fun with colleagues Wechsel der Textebene/Formatierungen Start and friends from everywhere in the world at the Stone Brewing World Bistro & Gardens - Liberty Station http://www.stonebrewing.com/visit/bistros/liberty-station

We will meet after the last scientific sessions at 6pm, PDT at the registration hall and venture off in shared taxis to the venue. Alternatively, you can meet us at the venue from 6.30pm onwards (2816 Historic Decatur Rd)

Please find additional info and register at https://emeunet.eventsmart.com/events/emeunet-meet-acr-2017-san- diego/ Registration is free, at the bar you can order food and drinks, but please register so that we can contact you a few days before to confirm the final details. Click here to add the event to your own calendar

Let’s meet in San Diego Sunday November 5th 2017!

OCTOBER 2017 18 EDUCATIONAL EVENTS

EDUCATIONAL EVENTS OCTOBER-DECEMBER 2017

OCTOBER 2017 18th EULAR Postgraduate Course o When and Where: 22 – 25 Oct 2017, Belgrade, Serbia Hilfslinien anzeigen über Menu: o Website: https://www.eular.org/edu_course_postgraduate.cfm

Croatian Society of Rheumatology 19th Annual Meeting Folie in Ursprungsform o When and Where: 26 – 29 Oct 2017, Dubrovnik, Croatia o Website: http://hrd-kongres.org/ Wechsel der Textebene/Formatierungen Start 5th Annual Meeting of the International Cytokine & Interferon Society (ICIS) o When and Where: 29 Oct – 2 Nov 2017, Kanazawa, Ishikawa, Japan o Website: http://cytokinesociety.org/cytokines2017/

NOVEMBER 2017 ACR Annual Meeting o When and Where: 3 – 8 Nov 2017, San Diego, USA o Website: https://www.rheumatology.org/Annual-Meeting

19th Asia Pacific League of Associations for Rheumatology Congress (APLAR) o When and Where: 16 – 20 Nov 2017, Dubai, United Arab Emirates o Website: http://www.aplar2017.com/

54th National Congress of the Italian Society of Rheumatology o When and Where: 22 – 25 Nov 2017, Rimini, Italy o Website: http://www.congressosir2017.com

5th Latin American Congress on Autoimmunity (LACA 2017) o When and Where: 27 – 29 Nov 2017, Cancun, Mexico o Website: http://www.laca2017.kenes.com/ DECEMBER 2017 Quality Bone Densitometry: Performance, Interpretation, and Clinical Application for Clinicians o When and Where: 2 – 3 Dec 2017, Chicago, USA o Website: http://www.iscd.org/education/cmece-live-courses/osteoporosis- essentials/clinicians/

11th European Workshop on Immune-mediated Inflammatory Diseases o When and Where: 14 – 16 Dec 2017, Utrecht, The Netherlands o Website: http://www.ewimid.com/

ISCD Osteoporosis Essentials o When and Where: 15 – 16 Dec 2017, Brussels, Belgium o Website: https://www.iscd.org/event/brussels-belgium-osteoporosis-essentials/

OCTOBER 2017 19 EDUCATIONAL EVENTS

THE EULAR ON-LINE COURSES

All EULAR courses, as electronic ways of continuous medical education in rheumatology, are managed by a scientific course committee responsible for the structure and content of the courses and for ensuring regular quality control and advancement. Teams of expert authors are regularly reviewing and updating the courses to keep up with the newest developments in the field.

Hilfslinien anzeigen über Menu: REGISTRATION IS NOW OPEN

Folie in Ursprungsform

Course Duration Registration and More Information Wechsel der Textebene/Formatierungen Start 12th EULAR On-line Course on 2 years https://www.eular.org/edu_online_course.cfm Rheumatic Diseases

9th EULAR On-line Course on https://www.eular.org/edu_online_course_ctd.cf 9 months Connective Tissue Diseases (CTD) m 7th EULAR On-line Course on https://www.eular.org/edu_online_course_ssc.cf 9 months Systemic Sclerosis (SSc) m 6th EULAR On-line Introductory https://www.eular.org/edu_online_course_msus. 7 months Ultrasound Course cfm

4th EULAR / PReS On-line Course in https://www.eular.org/edu_online_course_paedi 9 months Paediatric Rheumatology atric.cfm

3rd EULAR On-line Course for Health https://www.eular.org/edu_online_course_hpr.cf 9 months Professionals m

The EULAR On-line Courses on Rheumatic Diseases, CTDs, SSc and US are also available as APP

PARTICIPANT FEEDBACK:

“Ultrasonography is essential for the training of Rheumatologists and represents a key aspect of patient’s evaluation. The EULAR On-line Introductory Ultrasound Course offers theoretical basic skills on musculoskeletal ultrasound in rheumatic diseases as well as in healthy subjects. The high quality of contents as well as the experience of the Faculty are the two main reasons to join this course. Moreover, the website is straightforward and very easy to use. Upon passing the final examination, EULAR releases a certificate. This course is very useful for Rheumatologists who would like to acquire a basic theoretical knowledge on musculoskeletal ultrasound.”

“I attended the EULAR On-line Introductory Ultrasound Course. It is a well structured basic course on ultrasonography that is divided in different modules according to the different anatomical sites. Each module includes specific exercises and the final test. I found this course very interesting and it provided me with a complete overview of ultrasonography in rheumatology. I would recommend this course as to me it was overall more useful and formative compared to some different on-site courses I previously attended.”

OCTOBER 2017 20 EDUCATIONAL EVENTS

2ND EULAR IMMUNOLOGY COURSE

Understanding the immunologic background of autoimmune-mediated rheumatic diseases is a fundamental prerequisite for both clinicians to make wise decisions in complex medical settings and researchers to develop effective and tolerable targeted therapies. The ambition of Hilfslinien anzeigen über Menu: this course is to bring both parties together for working on challenges in immunology and accelerating the translation of basic findings into clinical practice.

Folie in Ursprungsform The main goal of the course is to increase the knowledge and skills of young researchers in immunology and stimulate critical thinking in the design of experimental studies. This course is Wechsel der Textebene/Formatierungen Start designed as the perfect complement to the EULAR online course on rheumatic diseases and the EULAR postgraduate course, by consolidating your knowledge in immunology in a more interactive way. However, previous participation of these courses is not mandatory.

Furthermore, this course brings together clinicians and scientists, thereby facilitating interaction, discussion, and collaboration in translating basic immunology findings into clinical practice. People participating in this course can enter an immunology and translational rheumatology network to facilitate communication between European groups working in the field of immunology and translational research dedicated to rheumatic diseases.

This is a selective course, with competitive admission, for young rheumatologists and rheumatology researchers with a confirmed interest in immunology. The course is a compact, one and a half day event on immunology and translational research with a special emphasis on hot immunology topics and on the design, interpretation and analysis of basic or translational research projects. The course is designed to facilitate problem- and case-oriented learning to enhance the interactions among participants and between participants and the faculty.

Next EULAR Immunology Course will take place on

6-7 April 2018 in Lisbon, Portugal

REGISTRATION OPEN, CLOSES 1st DECEMBER 2017

TRAVEL BURSARIES ALSO AVAILABLE

For information and to register visit: http://www.eular.org/eular_course_on_immunology.cfm

OCTOBER 2017 21 EDUCATIONAL EVENTS

EULAR COURSE ON HEALTH ECONOMICS IN RHEUMATOLOGY

Health economics covers an important and increasing part of the assessment of burden of disease. It has become an essential discipline to estimate the benefits and costs of health care interventions, as well as to explore how therapeutic innovations can be made available to Hilfslinien anzeigen über Menu: physicians and patients in our quite constraint economic environment.

Folie in Ursprungsform The EULAR Course on Health Economics in Rheumatology aims to present the key principles of health economics applied to rheumatic or musculoskeletal disorders:

Wechsel der Textebene/Formatierungen Start Basic principles in health economics and health technology assessment Economic burden (Cost-of illness) assessment Cost-effectiveness and cost-utility analysis using model- or trial-based data for a better understanding of drug pricing The course will be based on interactive learning and practical training

The participant profile for this two-day course is the following:

- Young scientists working in the field of RMD

- Rheumatologists new to the field of Health Economics and little experience in this area

- Rheumatologists with the intention to involve in a Health Economics project in the near future

- Patient Research Partner representatives

Young researchers attending this course will also have an opportunity to get together for future collaborations.

This course will be selective, with competitive admission (send in your CV and motivation text with your online registration) The number of attendees is limited to 30.

The EULAR Course on Health Economics in Rheumatology

will take place on

5-6 April 2018 in Prague, Czech Republic

REGISTRATION OPEN SOON, CLOSES 31st JANUARY 2018

COURSE BURSARIES ALSO AVAILABLE

For information and to register visit: https://www.eular.org/edu_course_health_economics_on_rheumatology.cfm

OCTOBER 2017 22 EDUCATIONAL EVENTS

25TH EULAR ULTRASOUND COURSES

The aim of this annual multi-level course is to cover the whole spectrum of conditions in which musculoskeletal ultrasound (MSUS) could be used in rheumatology practice and research.

Hilfslinien anzeigen über Menu: The advanced course (for up to 50 participants with considerable experience in MSUS) focuses on difficult issues within MSUS and emerging research fields in Folie in Ursprungsform MSUS (contrast enhanced, 3D, quantification of inflammation). This includes time for discussion with expert rheumatologists and radiologists in MSUS.

Wechsel der Textebene/Formatierungen Start The intermediate course (for up to 50 participants with some experience in MSUS) aims at consolidating standardised MSUS scanning methods according to EULAR guidelines, as well as describing and identifying musculoskeletal lesions/abnormalities by US and knowing the role of MSUS in different musculoskeletal pathologies (inflammatory, degenerative and/or traumatic). The standardised approach in the study of the various anatomic regions as well as the future development of US technique and its role as a research tool is discussed.

For colleagues interested in taking the basic level ultrasound course, please note that it is a EULAR recommendation to first complete the EULAR Online Introductory Ultrasound Course which provides the basic knowledge in form of a 7 module online course including video clips and a final exam. A new online course starts each September.

The EULAR Ultrasound Course

will take place on

10-13 June 2018 in Amsterdam, The Netherlands, prior to EULAR

REGISTRATION OPEN SOON

COURSE BURSARIES ALSO AVAILABLE

For information and to register visit: https://www.eular.org/edu_course_ultrasound.cfm

OCTOBER 2017 23 EDUCATIONAL EVENTS

8TH EULAR COURSE ON CAPILLAROSCOPY

The aim of this intensive and interactive course is to provide all participants with an update on the power of the safe and non-invasive nailfold videocapillaroscopy (NVC) technique in the field of rheumatic diseases, in particular for the early diagnosis of scleroderma spectrum diseases, its predictability and prognostic value, as well as its role as a tool for therapeutic follow up. Hilfslinien anzeigen über Menu: The EULAR course on NVC first ran in 2004 and has been successfully tested Folie in Ursprungsform for both beginners and already trained operators in microcirculation investigations, by over 740 total participants from almost 52 different countries. Participants will be fully involved in interactive theoretical and practical Wechsel der Textebene/Formatierungen Start capillaroscopic sessions. Updated clinical sessions concerning the diagnostic/prognostic value of NVC in diseases such as systemic sclerosis. Links between capillaroscopic patterns and biomarkers such as autoantibodies will also be discussed. In particular, reading and scoring (manual and automated systems) of videocapillaroscopic images of living patients will be discussed and their predictive value to identify possible clinical complications (i.e. digital ulcers in systemic sclerosis, lung involvement etc.) will be analyzed.

New sessions on practical evaluation of peripheral blood flow by laser doppler and LASCA imaging have been introduced. Lessons and practical sessions on skin ultrasound (US) evaluation will be also available and will be combined with the severity of the videocapillaroscopic images (patterns) in living patients.

At the end of this excellent course that is delivered by a faculty formed by many of the world experts in this area, the participants will be able to use capillaroscopy for their day-to-day assessment and follow-up, in particular of patients affected by scleroderma spectrum diseases.

The next EULAR Capillaroscopy Course

will take place on

13-15 September 2018 in Genova, Italy

REGISTRATION WILL OPEN IN 2018

COURSE BURSARIES ALSO AVAILABLE

For information and to register visit: https://www.eular.org/edu_course_capillaroscopy.cfm

OCTOBER 2017 24 WORLD ARTHRITIS DAY EMEUNET @ EULAR BRUSSELS CONFERENCE ON THE FUTURE OF HEALTH RESEARCH AND INNOVATION AFTER HORIZON 2020

The 12th of October 2017 marked the World Arthritis Day. In light of this and as in previous years, EULAR organised a conference in Brussels to raise awareness on Rheumatic and Musculoskeletal Diseases (RMDs), this year looking at the future of health research and innovation after Horizon 2020. Discussions focused on identifying priorities in health research and innovation as well as on analysing examples of successful Hilfslinien anzeigen über Menu: research proposals to learn from previous achievements and plan future developments. This meeting gathered representatives of different stakeholders providing their point of view and perspective: The three EULAR

Folie in Ursprungsform pillars, were represented by the EULAR President Prof. Johannes Bijlsma, the Vice President of EULAR representing people with arthritis and rheumatism (PARE) Dieter Wiek, and the EULAR Vice President representing health professionals Prof. Tanja Stamm. The exceptionality of this meeting is outlined by Wechsel der Textebene/Formatierungen including representatives from the European Parliament, the European Patients’ Forum, the European Start Commission, national patients’ organizations, and national rheumatology societies from EULAR countries. The meeting included introductory lectures followed by four group workshops, a reporting back of the results to all participants, and a plenary discussion on the possible impact of the workshop results on EU policy makers to improve conditions at the European level.

Four main topics were addressed in these workshops: “Horizon 2020: lessons for the next research framework programme” “Challenges in transferring research findings and innovations into clinical practice” “Engagement of patients in research and innovation” “Public-Private partnership in research and innovation”

The main points stemming out of the workshops were : -Patients should be actively engaged throughout the entire process of the development of research projects. The involvement of patients improves methodology, outcomes, credibility of the results, and translation into practice. -Relevant stakeholders should ensure data sharing and allow the access to different sources of information, to foster patients’ education and optimise researchers’ efforts. -Financial issues are a major barrier to the development of medical research and the implementation of results in clinical practice. A strong collaboration starting at EU level and engaging researchers, patients and other stakeholders, would allow an optimal allocation of funds and eventually the achievement of the overarching priority: the benefit of patients.

Alessia Alunno, Alexandre Sepriano, and Paul Studenic represented EMEUNET at this event to bring input from the experiences and viewpoints of young rheumatologists. The conference was covered via live streaming and twitter (official hashtag: #EULARBrussels2017), so that everyone could follow the developments from home over course of the day. EMEUNET also contributed to the ARD twitter platform, as well as EMEUNET Facebook, spreading the news further and ensuring high engagement across these platforms. EULAR provides a social wall (https://walls.io/EULARBrussels2017) with the main tweets of this conference.

From left to right: Alexandre Sepriano EMEUNET representative, Paul Studenic EMEUNET representative, Prof Johannes Bijlsma EULAR President, Neil Betteridge EULAR Public Affairs Liaison Officer, Alessia Alunno EMEUNET representative

OCTOBER 2017 25 BE PART OF THE EMEUNET COMMUNITY JOIN EULAR TASK FORCES AND COMMITTEES

Young investigators of EMEUNET are an integral part of all task forces and committees working on new EULAR recommendations. This is a wonderful chance for EMEUNET to increase its visibility and for you to accelerate your academic career. Hilfslinien anzeigen über Menu: The last call came in October from the EULAR recommendations for the Folie in Ursprungsform for the role of the nurse in in the management of chronic inflammatory arthritis. Wechsel der Textebene/Formatierungen Start Take a look at emails from EMEUNET and find the opportunity most suitable for you!

SHARE YOUR IDEAS!

Over the years EMEUNET has developed several projects covering different topics and areas of interest. However, we appreciate any suggestions and welcome new ideas to expand on what we currently offer to EMEUNET members. Make your voice heard and share your ideas with us!

It is easy, just write down some lines to summarize your proposal and send it either via email at [email protected] or through our website (http://emeunet.eular.org/contact_us.cfm). Don’t forget to provide your contacts so we can come back to you for additional details!

We look forward to hearing from you!!!

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