WIPAWEE “JOY” WINUTHAYANON, BS.N., PH.D. School of Molecular Biosciences Center for Reproductive Biology College of Veterinary Medicine Washington State University Biotechnology Life Science Building, Pullman, WA 99164 509.335.8296 | [email protected] | https://labs.wsu.edu/winuthayanon

EDUCATION

2003-2009 Ph.D. Human Physiology Mahidol University, Bangkok, Thailand Doctoral Program in the Department of Physiology, Faculty of Science Evaluation and characterization for the estrogenic activity of diarylheptanoids from comosa PI: Pawinee Piyachaturawat, Ph.D. 1998-2002 B.Sc. Nursing Science (Second Class Honors) Mahidol University, Bangkok, Thailand School of Nursing, Faculty of Medicine Ramathibodi Hospital Specialty: Nursing and Midwifery

POSITIONS effective 07/2021 Associate Professor (Tenured) School of Molecular Biosciences, College of Veterinary Medicine, Washington State University (WSU), Pullman, WA Training Faculty, MARC-WSU Program (05/2021–present) Graduate Faculty, adjunct (05/2020–present) Clinical & Translational Sciences, Dept. of Veterinary Clinical Sciences, WSU Faculty Research Mentor (06/2018–present) Pacific Northwest Louis Stokes Alliance for Minority Participation (LSAMP), WSU Faculty Research Mentor (01/2016–present) Team Mentoring Program (TMP), WSU 08/2015–06/2021 Assistant Professor School of Molecular Biosciences, College of Veterinary Medicine, WSU 08/2009–07/2015 Post-doctoral Fellow National Institutes of Health/National Institute of Environmental Health Sciences (NIH/NIEHS), Research Triangle Park (RTP), NC Reproductive & Developmental Biology Laboratory PIs: Kenneth Korach, Ph.D. and Carmen Williams, M.D. Ph.D. 03/2007–06/2008 Pre-doctoral Fellow NIH/NIEHS, Research Triangle Park, NC Laboratory of Reproduction and Developmental Toxicology PI: Kenneth Korach, Ph.D. 06/2003–01/2009 Graduate Research Assistant Department of Physiology, Faculty of Sciences, Bangkok, Thailand PI: Pawinee Piyachaturawat, Ph.D. 05/2002–03/2003 Registered Nurse Orthopedics Unit, Ramathibodi Hospital, Bangkok, Thailand Surgery Unit, Phyathai Hospital, Bangkok, Thailand

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AWARDS & HONORS 09/2020 Dean’s Outstanding Junior Faculty Award, College of Veterinary Medicine, WSU 04/2020 Excellence in Undergraduate Mentor Award, School of Molecular Biosciences, WSU 10/2019 Winner of WSU Largest New Individual Grant Award for FY 2019 01/2017 J Molecular Endocrinology’s 2nd most downloaded review article of the year (for 2016) 01/2017 J Endocrinology’s most downloaded review article of the month 02/2015 Research article selected by NIEHS Intramural Research Division as “paper of the month” 02/2014 NIH Cross-Divisional Group Merit Award, NIEHS, NIH 06/2013 Winner of Presidential Poster Competition, The Endocrine Society Meeting 06/2013 Research article selected by NIEHS Intramural Research Division as “paper of the month” 06/2012 Outstanding Abstract Award, The Endocrine Society Meeting 10/2011 Winner of the Fellows Awards for Research Excellence (FARE), NIH 02/2011 Research article highlighted in NIEHS Environmental Factor as "work of great interest" 01/2011 Research article selected by NIEHS Assembly of Scientists as “paper of the month” 2005–2009 Scholarship, the Royal Golden Jubilee PhD Program, Thailand Research Fund

RESEARCH ACTIVITIES • Steroid action in the female reproductive tract during pregnancy establishment • Semen liquefaction: a novel target for women-controlled contraceptive products

GRANT AND FELLOWSHIP SUPPORT Since joining WSU, I have been awarded an R01 research grant from NIH (R01HD097087; $1,062,500 direct costs) and two NIH Diversity Supplement Awards (R01HD097087-01S1 and R01HD097087-02S1; $26,431 and $88,288, respectively). Although X01HD104425 and HD106634 awards do not result in a direct cost, the actual cost for the project (at least $169,911) is paid for by the NIH. Moreover, the findings from these research projects will likely lead to a patent for a novel contraceptive drug development. In total, my research program has been awarded $1,177,219 of direct costs by the extramural funding. Current

1. R01 HD097087 – NIH/NICHD Role: PI 03/12/19 – 02/29/24 The actions of steroid hormones on oviduct function Direct cost: $1,062,500 2. R01 HD097087-02S1 diversity supplement – NIH/NICHD Role: PI 05/15/20 – 05/14/22 The actions of steroid hormones on oviduct function (to Emily Harris) Direct cost: $88,288 3. X01 HD104425 – NIH/NICHD Role: PI 07/01/20 – 06/30/21 Synthesis and optimization of KLK3 inhibitors for novel contraceptive purposes Direct cost: N/A – This is a service request to the Chemical Screening & Optimization Facility Contract cost to SRI International paid for by the NICHD. Not searchable in the NIH RePORTER. 4. X01 HD106634 – NIH/NICHD Role: PI 04/01/21 – 03/31/22 Screening to identify novel inhibitors of KLK3 from established chemical libraries for contraceptive drug discovery Direct cost: N/A – This is a service request to the Chemical Screening & Optimization Facility Not searchable in the NIH RePORTER. Pending 5. R01 HD102345-01A1 – NIH/NICHD Role: admin PI 05/01/21 – 04/31/26 Disruption of semen liquefaction using protease inhibitor as a new contraceptive Direct cost: $3,544,540 25th percentile mPI: Martin Matzuk (Baylor College of Medicine) mPI: Ov Slayden (Oregon Health Science University, Oregon National Primate Research Center)

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6. F31 HD107807 Diversity – NIH/NICHD Role: Sponsor 09/01/21 – 08/31/23 The role of progesterone receptor in the oviduct epithelium for pregnancy establishment Direct cost: $29,862 PI: Emily Harris (McGlade), graduate student

Completed 7. R01 HD097087-01S1 diversity supplement – NIH/NICHD Role: PI 09/01/19 – 08/31/20 The actions of steroid hormones on oviduct function (to Gerardo Herrera) Direct cost: $26,431 8. WSU College of Veterinary Medicine Research Grant Role: PI 08/01/17 – 07/31/19 A novel contraceptive drug targeting semen liquefaction Direct cost: $20,000, intramural 9. WSU Center for Reproductive Biology Internal Seed Role: PI 09/01/17 – 08/31/19 Generation of Ovgp1Cre targeted knock-in mouse model using CRISPR/Cas9 technology Direct cost: $10,000, intramural 10. WSU New Faculty Seed Grant Role: PI 05/16/16 – 02/16/18 Identification of cell-type selective transcriptome regulation by hormones in the oviduct Direct cost: $15,000, intramural

Not funded, or Letters of intent/pre-proposal submitted but not invited for a full application

11. R01 HD102345 – NIH/NICHD (02/2020) Role: admin PI Not discussed Disruption of semen liquefaction using protease inhibitor as a new contraceptive 12. R01 HD098103-01A1 – NIH/NICHD (06/2020) Role: co-I, 10% effort 17th percentile Functional Analysis of Adult Endometrial Epithelial Stem Cells PI: James Pru, Department of Animal Sciences, WSU 13. R61 HD099744 – (R61/33) NIH/NICHD (11/2018) Role: PI Not discussed Disruption of semen liquefaction using protease inhibitor as a new contraceptive 14. R01 HD097087-01A1 – NIH/NICHD (07/2018) Role: PI Withdrawn The actions of steroid hormones on oviduct function 15. NSF CAREER: 1843053 – NSF (07/2018) Role: PI Not funded CAREER: Steroid Hormones and the Function of the Oviduct 16. LOI: Beckman Young Investigator Award– Arnold Beckman Foundation (08/2017) Role: PI Semen liquefaction: Novel target for contraceptive method Not invited for full application 17. R01 AI123549-01A1– NIH/NIAID (06/2017) Role: co-I, 5% effort 31st percentile Chlamydia interactions with epithelial cells PI: Rey Carabeo (School of Molecular Biosciences, WSU) 18. R21 HD094394 – NIH/NICHD (02/2017) Role: PI Not discussed In Vivo Regulation of Semen Liquefaction by the Female Reproductive Tract 19. R21 HD090195 – NIH/NICHD (02/2016) Role: PI Not discussed Kallikreins in female reproductive tract: new players in semen liquefaction 20. Pre-proposal: Pew Scholars in Biomed Sci (06/2015) Role: PI Not selected for full app. Roles of and progesterone during embryo development & transport in the oviduct 21. K99 HD081156 – NIH/NICHD (03/2014) Role: PI Impact score = 24 Hormonal effects on oviductal ciliated cell function and embryo transport

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PUBLICATIONS [Citations number] Google Scholar total 823 citations, h-index = 14, i10-index = 17

Primary research papers (*Corresponding author) 1. McGlade EA, Herrera GG, Stephens KK, Olsen SLW, Winuthayanon S, Guner J, Hewitt SC, Korach KS, DeMayo FJ, Lydon JP, Monsivais D, and Winuthayanon W*. (2021) Cell-type specific analysis of physiological action of estrogen in mouse oviducts. FASEB J. 35;e21563. [1]

2. Hewitt SC, Carmona M, Foley G, Donoghue LJ, Lierz SL, Winuthayanon W, and Korach KS. (2020) Peri- and post-pubertal estrogen exposures of female mice optimize uterine responses later in life. Endocrinology. 161: 1-12. [1] Selected for the commentary on Endocrinology

3. Griffiths R, Pru C, Behura S, Cronrath A, McCallum M, Kelp N, Winuthayanon W, and Pru K. (2020) AMPK is required for uterine receptivity and normal responses to steroid hormones. Reproduction. 159: 707-717. [2]

4. Barton BE, Rock JK, Willie AM, Harris EA, Herrera GG, Anamthathmakula P, and Winuthayanon W*. (2020) Serine protease inhibitor disrupts sperm motility leading to reduced fertility in female mice. Biol Reprod. 103: 400-410 [2]

5. Herrera GG, Lierz SL, Harris EA, Donoghue LJ, Hewitt SC, Rodriguez, KF, Jefferson WN, Lydon JP, DeMayo FJ, Williams CJ, Korach KS, and Winuthayanon W*. (2020) Oviductal retention of embryos in female mice lacking estrogen receptor a in the isthmus and the . Endocrinology. 161: 1-12. [1]

6. Li S, Beedle M-T, Herrera GG, Tam KK, and Winuthayanon W*. (2019) Deletion of kallikrein 1b5 (Klk1b5) has no impact on fertility in mice. Mol Reprod Dev 86: 611-613.

7. Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ, Adelman K, and Korach KS. (2019) Negative elongation factor is essential for endometrial function. FASEB J. 33: 3010-3023. [1]

8. Li S, Herrera GG, Tam KK, Lizarraga JS, Beedle M-T, and Winuthayanon W*. (2018) Estrogen action in the epithelial cells of the mouse regulates neutrophil infiltration and vaginal tissue integrity. Sci Rep. 8: 11247. [22]

9. Li S and Winuthayanon W*. (2017) Collection of post-mating semen from the female reproductive tract and measurement of semen liquefaction in mice. J Vis Exp. 129: e56670. [2]

10. Siller SS, Sharma H, Li S, Holtzman MJ, Winuthayanon W, Colognato H, Holdener B, Li F-Q, and Takemaru K-I. (2017) Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway ciliogenesis. PLoS Genetics. 13: e1007128. [21]

11. Winuthayanon W*, Lierz SL, Delarosa KC, Sampels SR, Donoghue LJ, Hewitt SC, and Korach KS (2017). Juxtacrine activity of estrogen receptor a in uterine stromal cells is necessary for estrogen- induced epithelial cell proliferation. Sci Rep. 7: 8377. [31] • Post-publication peer reviewed recognition in F1000 as “very good”

12. Hewitt SC, Winuthayanon W, Lierz SL, Hamilton KJ, Donoghue LJ, Ramsey JT, Grimm SA, Arao Y, and Korach KS. (2017) Role of ERa in mediating female uterine transcriptional responses to IGF1. Endocrinology. 158: 2427-2435. [9]

13. Thongon N, Boonmuen N, Suksen K, Wichit P, Chiroungdua A, Tuchinda P, Suksamrarn A, Winuthayanon W, and Piyachaturawat P. (2017) Selective estrogen receptor modulator (SERM)-like activities of diarylheptanoid, a phytoestrogen from Curcuma comosa, in breast cancer cells, preosteoblast cells, and uterine tissues. J Agric Food Chem. 65: 3490-3496. [19]

14. Li S, Garcia M, Gewiss RL, and Winuthayanon W*. (2017) Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo. PLoS Genetics. 13: e1006743. [11] • Featured in WSU News and others: “Fertility can hinge on uterus swimming conditions”

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15. Li S, O’Neill SRS, Zhang Y, Holtzman MJ, Takemaru K-I, Korach KS, and Winuthayanon W*. (2017). Estrogen receptor a is required for oviductal transport of embryos. FASEB J. 31:1595-1607. [26]

16. Winuthayanon W*, Bernhardt ML, Padilla-Banks E, Myers PH, Edin ML, Lih F, Korach KS, and Williams CJ*. (2015) Oviductal estrogen receptor a signaling prevents protease-mediated embryo death. eLIFE. 4: e10453. [45] • Highlighted in World of Reproductive Biology: “The Inconstant Oviduct”

17. Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Suksamrarn A, Piyachaturawat P, Bushel PR, and Korach KS. (2015) Development of phenotypic and transcriptional biomarkers to establish activity and potency of candidate xenoestrogens. Environ Health Perspect. 123: 334-52. [8]

18. Winuthayanon W, Hewitt SC, and Korach KS. (2014) Uterine epithelial cell ERa –dependent and – independent genomic profiles that underlie estrogen response. Biol Reprod. 95:1-10. [36]

19. Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, DeMayo FJ, Schütz G, and Korach KS. (2014) Novel DNA motif binding activity observed in vivo with an ERa mutant mouse. Mol Endo. 28: 899-911. [39]

20. Winuthayanon W, Piyachaturawat P, Suksamrarn A, Arao Y, Burns KA, Hewitt SC, Pedersen LC, and Korach KS. (2013) The natural estrogenic compound Diarylheptanoid (D3): in vitro mechanisms of action and in vivo uterine responses via estrogen receptor a. Environ Health Perspect. 121:433-9. [12]

21. Winuthayanon W, Hewitt SC, Orvis GD, Behringer RR, and Korach KS. (2010) Uterine epithelial estrogen receptor a is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci USA. 107: 19272-7. [188] • Post-publication peer reviewed recognition in F1000 as “must read paper”

22. Winuthayanon W, Piyachaturawat P, Suksamrarn A, Ponglikitmongkol M, Arao Y, Hewitt SC, and Korach KS. (2009) Diarylheptanoid phytoestrogens isolated from the medicinal Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms. Environ Health Perspect. 117: 1155-61. [61]

23. Winuthayanon W, Suksen K, Boonchird C, Chuncharunee A, Ponglikitmongkol M, Suksamrarn A, and Piyachaturawat P. (2009) Estrogenic activity of diarylheptanoids from Curcuma comosa Roxb. requires metabolic activation. J Agric Food Chem. 57: 840-5. [58]

Reviews and Book Chapters (*Corresponding author) 24. Anamthathmakula P and Winuthayanon W*. (2021) Prostaglandin-endoperoxide synthase 2 (PTGS2) in the oviduct: roles in fertilization and early embryo development. Endocrinology. 162: 1-14.

25. Harris EA, Stephens KK, and Winuthayanon W*. (2020) Extracellular vesicles and the oviduct function. Intl J Mol Sci. 21: 8280. [4]

26. Anamthathmakula P and Winuthayanon W*. (2020) Mechanism of semen liquefaction and its potential for a novel non-hormonal contraception. Biol Reprod. 103: 411-426. [3]

27. Barton BE, Herrera GG, Anamthathmakula P, Rock JK, Willie AM, Harris EA, Takemaru K-I, and Winuthayanon W*. (2020) Roles of steroid hormones in oviductal function. Reproduction. 159: R125- R137. [12]

28. Olsen, LW, Li S, and Winuthayanon W*. (2018) Embryo Transport. In: MK Skinner (ed.), Encyclopedia of Reproduction, vol. 3, 2nd ed. Academic Press, London: Elsevier. pp357–363.

29. Winuthayanon W* and Li S. (2018) Fallopian Tube/Oviduct: Structure and Cell Biology. In: MK Skinner (ed.), Encyclopedia of Reproduction, vol. 2, 2nd ed. Academic Press, London: Elsevier. pp282-290. [1]

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30. Li S and Winuthayanon W*. (2017) Oviduct: Roles in fertilization and early embryo development. J Endocrin. 232: R1-26. [106] • J Endocrinology’s top downloaded article of the month

31. Hewitt SC, Winuthayanon W, and Korach KS. (2016) What’s new in estrogen receptor action in the female reproductive tract. J Mol Endocrin. 56: R55-71. [84] • J Mol Endocrin’s second most downloaded article of the year for 2016

32. Binder AK, Winuthayanon W, Hewitt SC, Couse JF, and Korach KS. (2015) Steroid receptors in the and uterus. In: Plant TM and Zeleznik AJ (eds.), Knobil and Neill’s Physiology of Reproduction, vol. 1, 4th ed. London: Elsevier; 1099-193. [16]

33. (Magazine) Deroo BJ, Burns KA, Winuthayanon W, and Korach KS. (2009) Potential effects for environmental xeno-oestrogens: Pollution and fertility. The Biochemist. 31: 22-6. [1]

INVITED TALKS (honorarium received, or travel reimbursed marked by *)

Scientific oral presentations

TBD* Invited, Eastern Carolina University, Dep. of Anatomy & Cell Biology, Greenville, NC TBD* Invited, NIH/NIEHS, Estrogen Receptor Action Symposium, RTP, NC 03/2021 Western Washington University, Biology Department, Bellingham, WA 09/2020 Washington State University, School of Molecular Biosciences, Pullman, WA 12/2019 The 53st Gene Families and Isozymes meeting, Roatan, Honduras 11/2019* Molecular Physiology and Biophysics Dep., Baylor College of Medicine, Houston, TX 07/2019* The Annual Meeting of the Society for the Study of Reproduction, San Jose, CA 06/2019* NIH/NIEHS, Reproductive & Developmental Biology Laboratory, RTP, NC 06/2019* Northwest Reproductive Scientific Symposium (NWRSS), Astoria, OR 02/2019* University of Texas at San Antonio, Cell & Molecular Biology seminar series, San Antonio, TX 09/2018 Washington State University, School of Molecular Biosciences, Pullman, WA 08/2018 Washington State University, Integrated Program in Biomedical Sciences, Pullman, WA 08/2018* Gordon Research Conference: Mammalian Reproduction, Lucca, Italy 06/2018 Washington State University, Center for Reproductive Biology Retreat, Orofino, ID 06/2018* NIEHS, Reproductive & Developmental Biology Laboratory Annual Retreat, Durham, NC 12/2017 The 51st Gene Families and Isozymes meeting, Kona, HI 07/2017* Gordon Research Conference: Fertilization & Activation of Development, Holderness, NH 07/2016 The Annual Meeting of the Society for the Study of Reproduction, San Diego, CA 08/2016 Washington State University, Integrated Program in Biomedical Sciences, Pullman, WA 06/2016 Northwest Reproductive Sciences Symposium, Philomath, OR 08/2015 Washington State University, Integrated Program in Biomed Sciences, Leavenworth, WA 07/2015 Washington State University, Center for Reproductive Biology, Moscow, ID 11/2014* Washington State University, School of Molecular Biosciences, Pullman, WA 11/2014 NIEHS Science Day, Research Triangle Park, NC 06/2012 The Endocrine Society’s 94th Annual Meeting, Houston, TX 10/2011* National Institutes of Health (NIH) Research Festival, Bethesda, MD 08/2011 The Annual Meeting of the Society for the Study of Reproduction, Portland, OR 08/2010 The Annual Meeting of the Society for the Study of Reproduction, Milwaukee, WI 11/2009 Endometrium Interest Group, University of Chapel Hill, Chapel Hill, NC

POSTER PRESENTATIONS (selected) at NATIONAL & INTERNATIONAL MEETINGS

(*honorarium received, or travel reimbursed, #presenter) 10/2020 The Society for the Study of Reproduction, Contraceptive Research symposium. A virtual conference. • Selected for an oral presentation 03/2020 The Society for Reproductive Investigation (SRI) Annual Meeting, Vancouver, BC, Canada. Abstract was accepted but the meeting was cancelled due to the pandemic.

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07/2019 Gordon Research Conference: Fertilization and Activation of Development, Holderness, NH 05/2019 Gordon Research Conference: Germinal Stem Cell Biology, Hong Kong, China 08/2018 Gordon Research Conference: Mammalian Reproduction, Lucca, Italy. 07/2015 Annual Meeting of the Society for the Study of Reproduction, San Juan, Puerto Rico. 08/2014 Gordon Research Conference “Mammalian Reproduction”, New London, NH. 03/2014 Keystone Symposia: Cilia, Development and Human Disease, Tahoe City, CA. 07/2013 Annual Meeting of the Society for the Study of Reproduction. Montréal, Canada. 06/2013 The Endocrine Society’s 95th Annual Meeting, San Francisco, CA. • Outstanding abstract award 08/2012 Annual Meeting of the Society for the Study of Reproduction. State College, PA. 03/2012 Triangle Consortium for Reproductive Biology: Reproductive Tract Organogenesis. Durham, NC. 03/2011 Triangle Consortium for Reproductive Biology: Gamete Development and Function. Durham, NC. 04/2008 FASEB Meeting, Experimental Biology. San Diego, CA.

TEACHING ACTIVITIES

Academic Teaching Activities

2019-present MBioS 494: Senior Project in Molecular Biosciences (45 lectures, 3-Credit), Fall Semesters. Develop lesson plans/curriculum and teach a semester-long senior capstone course on topics of stem cells, gene editing, assisted reproductive technologies, and bioethics 2019-present MBioS 529: Selected Topics in Cell Biology: Molecular Cell Signaling (15 lectures, 1- Credit), Spring Semesters. Develop lesson plans/curriculum and teach for a 5-week module on Cell Signaling for graduate students in the CVM. 2019-present Making Figures for Publications (1 workshop) Develop and teach a 2-hr workshop on “How to make scientific figures for proposals and publications” given every Summer for graduate students in the department 2016-present MBioS 499 (3-Credit): Special Problems: Fall and Spring Semesters Mentor undergraduate students to perform research projects in the laboratory 2016, 2019, & Honors 450: Honors Thesis or Project: Spring & Fall Semesters 2020 Serve as thesis advisor and mentor Honors undergraduate students on conducting biomedical research projects 2016-2019 MBioS 579: Molecular Biosciences Seminar (15 lectures, 1-Credit), Fall and Spring Semesters, deliver lecture on “Scientific Seminar Presentation” as well as evaluated and gave constructive feedback to students on their performance 2016-2019 TBE 564.01: Topics in Biomedical Experimentation: Philosophy of Experimental Design (15 lectures), Fall/Spring Semesters Team-taught 3 lectures/week with Dr. Steve Simasko for 16-23 graduate students in the Integrated Program in Biomedical Sciences (iPBS) program 2018 MBioS 503: Advanced Molecular Biology (16 lectures, 3-Credit), Fall Semester Developed lesson plans/curriculum and taught the first section of the course (5-week) for graduate students in the College of Veterinary Medicine and others within WSU. 2018 MBioS 494: Senior Project in Molecular Biosciences (1 guest lecture), Fall Semester Delivered a lecture on “Life as Young Academic” 2017 MBioS 401/501: Cell Biology (1 lecture), Spring Semester Delivered lectures on “Signaling by Cytosolic Receptors”

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2017 MBioS 563: Deconstruction of Research (2 lectures), Fall Semester Delivered a lecture on research project and participated in scientific discussion on research topics presented. 2016 MBioS 498 (3-Credit): Directed Research: Fall Semester Mentored undergraduate student to conduct a research project in the laboratory. 2014 Bio373-01 Human Anatomy & Physiology I, Adjunct lecturer, Shaw University, Raleigh, NC, Fall semester. Team taught two lectures/week with Dr. Paulette Dillard for an 18-week course for 23 pre-health undergraduate students 2013 BIOG 5120 Graduate Genetics, Guest lecturer, Department of Biology, North Carolina Central University (NCCU), Durham, NC Developed and lectured on “Animal Models” for 6 graduate students 2005-2006 Medical Physiology Laboratory, Teaching assistant, Faculty of Science, Mahidol University, Thailand. Set up, lectured, supervised, graded quizzes and exams for 3 laboratory sessions (mechanical heart model, pulmonary & respiratory function in man, and water balance in man) to a total of ~300 medical students.

STEM Outreach Activities (honorarium received & travel reimbursed marked by *)

03/2020 Imposter Syndrome (1 workshop), WSU Professional Development Initiative, WA Developed and led a 1-hr workshop on “Imposter Syndrome” for graduate students 01/2020 Imposter Syndrome (1 lecture/panel discussion) Conference for Undergraduate Women in Physics (CUWiP), Pullman, WA Developed a lecture and served on panel discussions for a workshop on “Imposter Syndrome” for 40-45 undergraduate students from the Northwestern regions in STEM & Physics disciplines. 01/2020 Race & Gender in STEM (1 lecture/panel discussion), CUWiP, Pullman, WA Developed a lecture and served on panel discussions for a workshop on “Race & Gender in STEM” for 16 undergraduate students from the Northwestern regions in STEM & Physics disciplines. 09/2020, Developing Your STEM Identity (1 lecture), WSU, Pullman, WA 09/2019 Developed and delivered a lecture on “Developing Your Identity in STEM: Identity as a Scientist, Engineer, health Professional” to 16-18 under-represented minority students 03/2019* Women in STEM (1 lecture), Pacific Northwest Louis Stokes Alliances for Minority, University of Washington, Seattle, WA Developed and delivered a lecture on “Women in STEM” to trainees and faculty in URM community in the Pacific Northwest. 10/2018 STEM Community (1 lecture), WSU TMP, Pullman, WA Developed and delivered a lecture on “Finding a Community in STEM” to 18 URM students 2013 & 2014 NIEHS Scholars Connect Program Science Training Workshop, Lecturer, NIH/NIEHS, RTP, NC Developed lesson plans/curriculum for two 2.5-day series of lectures and labs on theories and hands-on techniques routinely used in biomedical research to 10-14 undergraduate students 2013 & 2014 Citizen School Ambassador, Lecturer and workshop leader, Lowe’s Grove Middle School, Durham, NC Developed lesson plans/curriculum for two 10-week STEM apprenticeships geared toward underrepresented students in local middle school students

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RESEARCH MENTORING ACTIVITIES

Post-Doctoral Trainees Training period Current position 1. P. Anamthathmakula 06/2019-04/2021 Senior scientist, U. Missouri – Kansas City, MO 2. My-Thanh Beedle 05/2018-08/2018 Science teacher, JFK Catholic High School, WA 3. Shuai Li 01/2016-05/2018 Senior post-doctoral fellow, Mayo Clinic, MN Graduate Students (Chair of the Research Committee/Advisor, Underrepresented minority student*) 1. Jeffery Erickson* 03/2021-present PhD, Molecular Biosciences Program 2. Talahiva Bradshaw* 04/2020-present MS, Professional Science Master’s Program 3. Ryan Finnerty 03/2020-present PhD, Molecular Biosciences Program 4. Emily Harris* 03/2019-present PhD, Molecular Biosciences Program 5. Sierra Olsen 03/2017-12/2018# Histology Technician, Frontier Derm, WA #Left before completing the program due to medical reasons Post-baccalaureate trainee (Underrepresented minority student*) Training period Current position 1. Gerardo Herrera* 01/2019-07/2020 Graduate student, Kansas U Medical Center, KS 2. Sydney Lierz 01/2015-06/2015 Research Scientist, NC State University, NC 3. Emily Cox 06/2015-08/2015 Pediatric resident, Vilant Medical Center, NC

Undergraduate Students (Serve as Research Mentor, Underrepresented minority student*) Training period Current position 1. Parker Johnson 01/2021-present WSU student 2. Lilinoe McCanna* 01/2021-present WSU student 3. Jacob Pru 01/2021-present WSU student 4. Grace Melbuer 08/2020-present WSU student 5. Jenna Jeffries 08/2020-present WSU student 6. Long Nguyen 02/2020-present WSU student 7. Kalli Stephens* 09/2019-present WSU student 8. Kylie Butler* 02/2020-05/2021 Graduate student, Genetic Counseling, Brandeis U, MA 9. Jenna Rock 09/2018-05/2021 Pharmacy student, WSU, WA 10. Brooke Barton 01/2018-05/2020 Medical student, University of Washington, WA 11. Anna Willie 09/2018-05/2020 Research scientist, Molecular Epidemiology, WA 12. Devinae McNeill* 01/2018-05/2019 Patient representative, Swedish OB/GYN, WA 13. Lana Lim 08/2018-01/2019 Undergraduate research assistant, WSU 14. Gerardo Herrera* 01/2017-12/2018 Graduate student, Kansas U Medical Center 15. Keila Tam* 2016-2018 Laboratory assistant specialist, Clinical Laboratories of Hawaii, WA 16. Marleny Garcia* 2015-2017 Medical student, WSU School of Medicine, WA 17. Sofia O’Neill* 2015-2016 Microbiologist, WSU-WADDL, WA 18. Karena DeLaRosa* Spring-Fall 2016 Lost contact after dropping out due to family reasons 19. Jacob Lizarraga* Summer 2016 Biological Sample Management Specialist II, Adaptive Biotechnologies Corp., WA 20. Skylar Samples Summer 2016 Master of Science in Forensic Medicine, U of Michigan, MI 21. Catherine Haviland Summer 2014 Resident, U of Michigan Oral and Maxillofacial Surgery, MI 22. Emily Cox Summer 2013 Pediatric resident, Vilant Medical Center, NC

Advisory Graduate Student Committee Member at WSU 1. Nuha Haque 2021–present PhD School of Molecular Biosciences 2. Jalene Velazquez 2021–present PhD School of Molecular Biosciences 3. Mustika Rahmawati 2021–present PhD Department of Animal Sciences

Curriculum vitae | Wipawee “Joy” Winuthayanon | Updated on 5.18.2021 9

4. Jennifer David 2020–present PhD School of Molecular Biosciences 5. Rosario Rodolfo 2020–present MS Professional Science Master’s Program 6. Nathaniel Herrera 2020–2021 MS Department of Animal Sciences 7. Jacob Woodbery 2019–present PhD School of Molecular Biosciences 8. Christine Schleif 2019–present MS School of Molecular Biosciences 9. Quan Phan 2019–present PhD School of Molecular Biosciences 10. Katrina Gianopulos 2018–present PhD School of Molecular Biosciences 11. Korinn Murphy 2018–present PhD School of Molecular Biosciences 12. Liam Caven 2018–present PhD School of Molecular Biosciences 13. Shruthie Gnaneswaran 2018–2019 MS Professional Science Master’s Program 14. Richard Griffiths 2017–2019 MS Department of Animal Sciences 15. Katrina Jorgensen 2016–2018 MS Department of Animal Sciences 16. My-Thanh Beedle 2015–2018 PhD School of Molecular Biosciences 17. Estela Jauregui 2015–2017 PhD School of Molecular Biosciences 18. Nicole Kelp 2015–2017 PhD School of Molecular Biosciences 19. Angel Thalhofer 2015–2017 MS School of Molecular Biosciences 20. Andrea Smith 2015–2017 MS Department of Animal Sciences

Advising Graduate Student Rotation at School of Molecular Biosciences, WSU 1. Jalene Velazquez 2020 2. Jeffery Erickson 2020 3. Ryan Finnerty 2019 4. Emily Harris 2018 5. Rachel Gewiss 2017 6. Sierra Olsen 2017 7. Angel Thalhofer 2016

Honors Student Thesis Advisor/Committee Member at the Honors College, WSU 1. Jenna Jeffries 2020–present Thesis advisor 2. Grace Melbuer 2020–present Thesis advisor 3. Brooke Barton 2018–2020 Thesis advisor, Pass with distinction, Dean’s award class of 2020 4. Abbigail Kuck 2018 Committee member 5. Marissa Chuckwu 2018 Committee member 6. Sierra Gallaway 2018 Committee member 7. Marleny Garcia 2015–2017 Thesis advisor

SERVICE

Service on National and International Levels

Grant Reviewer at Study Sections and Other Agencies 2018, 2021 Ad hoc Reviewer, Integrative and Clinical Endocrinology & Reproduction (ICER) study section review panel, NIH 2020 Ad hoc Reviewer, National Science Foundation, Physiology Mechanisms and Biomechanics Program, Division of Integrative Organismal Systems 2019, 2020 Ad hoc Reviewer, Czech Science Foundation, Prague, Czech Republic 2020 Independent Expert Review for a post-doctoral fellowship, Lalor Foundation 2017 Ad hoc Reviewer, Ohio Cancer Research, Seed Money Research Grant

Other Services at Local, National, and International Events 2020–present Nominations committee member, Society for the Study of Reproduction (SSR) 2019–present Program committee member, SSR 2019–present Trainee-mentor luncheon/roundtable, SSR

Curriculum vitae | Wipawee “Joy” Winuthayanon | Updated on 5.18.2021 10

2019–present Abstract reviewer, SSR 2020 Judge, oral and poster competition, Annual Biomedical Research Conference for Minority Students (ABRCMS) conference 2017, 2020 Abstract reviewer, ABRCMS 2013–2015 Trainee representative, Lab. of Reproductive & Developmental Toxicology, NIH 2012–2013 Chief judge, Fellows Awards for Research Excellence, NIH, MD 2012 Registration desk, National Institute of Environmental Health Science Biomedical Career Fair, NC 2011, 2012 Reception desk, SSR

Editorial Board Member for Peer-Reviewed Scientific Journals 2021–present Co-Guest Editor, Frontiers in Physiology - Reproduction 2018–present Scientific Reports, Nature Publishing Group 2014–present Endocrine Connections, bioscientifica

Ad Hoc Reviewer for Peer-Reviewed Journals (2011-present)

Acta Histochimica, J of Molecular Endocrinology, Acta Obstetricia et Gynecologica Scandinavica J of Pathology, Annals Animal Sciences, J of Veterinary Medical Science, Biology, J of Visualized Experiments, Biology of Reproduction, Molecular Biology Reports, Biochimica et Biophysioca Acta, Molecular Cell Endocrinology, BMC Biology, Molecular Reproduction & Development, BMC Complementary & Alternative Medicine, Molecular Human Reproduction, Cells, Nature Communications, Clinical Experimental Immunology, Nutrients, Clinical Genetics, Phytochemistry, Communications Biology, PLoS Biology, Development, PLoS Genetics, Endocrine Connections, PLoS ONE, Endocrinology, PNAS Environmental Health Perspectives, Protein & Cell, European J of Pharmacology, Reproduction, FASEB J, Reproductive Biology & Endocrinology J, Frontiers in Physiology, Reproductive Sciences, International Journal of Molecular Sciences, Scientific Reports, J of Cell Physiology, Steroids J of Ethnopharmacology,

Service on WSU Committees

2021 Ad hoc reviewer, AFW Graduate Student Awards Reviewing Committee 2020, 2021 Ad hoc reviewer, SMB Undergraduate Scholarship Reviewing Committee 2020 Ad hoc reviewer, WSU Alcohol and Drug Abuse Research Program Grant 2020–present Committee member, SMB Graduate Affairs Committee 2019–2020 Committee member, SMB Director Hiring Committee 2019 Ad hoc reviewer, College of Veterinary Medicine Intramural Research Grant 2019 Co-host, WSU SMB Fall Conference 2019–present Co-chair, School of Molecular Biosciences (SMB) Graduate Recruitment Committee 2019–present Executive steering committee member, Center for Reproductive Biology 2018–present Faculty research mentor, Louis Stokes Alliances for Minority Participation 2017 Member, Functional Genomics Initiative Faculty Recruitment Committee 2017 Judge, oral/poster competition, NIH Protein Biotech Research Symposium 2017–present Member, SMB Graduate Recruitment Committee 2016, 2017 Ad hoc reviewer, College of Veterinary Medicine Poncin Fellowship 2016 Ad hoc reviewer, College of Veterinary Medicine Intramural Research Grant

Curriculum vitae | Wipawee “Joy” Winuthayanon | Updated on 5.18.2021 11

2016 Co-host, WSU SMB Fall Conference 2016–present Faculty research mentor, WSU Team Mentoring Program 2016–present Judge, poster competition, SURCA, CVM Research Symposium, Research Expo 2015–present Committee member, SMB Graduate Student Committee

PROFESSIONAL AFFILIATIONS

2012–present The Endocrine Society 2010–present Society for the Study of Reproduction 2008–2015 Triangle Consortium for Reproductive Biology 2002–2008 Nursing Association of Thailand

PROFESSIONAL DEVELOPMENT & CONTINUING EDUCATION 05/2021 What Inclusive Instructors Do, a 1-hour panel discussion on how to create equitable and welcoming environments for their learners, Stylus Publishing, Inc. 03/2021 Diversity, Equity, and Inclusion Summit, a two-hour webinar to learn about efforts and initiatives happening within WSU, meet people with shared interests and passions, and find ways to get involved in equity and social justice work, WSU. 10/2020 Workshop in Tissue Engineering and Modeling in Reproduction, a whole day virtual workshop offered by American Society for Reproductive Medicine, participated in a virtual discussion on emerging technology for tissue remodeling in the reproduction and ethical issues 04/2020 Member, NSF Values-based Academic Leadership Trajectories for Women in STEM (VAuLTS): The Northwest Regional Partnership, discuss and implement changes in systemic and policy barriers facing women in STEM, Pullman, WA 10/2019 Leadership Workshops given by Kevin Parker, entrepreneur and leadership expert, offered by WSU Administrative Professional Advisory Council, a full-day workshop on leading and creating change in the organization, WSU 09/2019 Mentoring Workshop given by Dr. Beronda Montgomery, Michigan State University, a half-day workshop focusing on building bridges to access and success as well as developing a personal philosophy and plan for impactful mentoring, WSU 08/2019 Workshop on Women Seeking Grants, a 2-hr workshop given by Dr. Susan Coady Kemnitzer - a retired National Science Foundation officer, WSU 04/2019 WSU & UI Women’s Leadership Conference, a full-day conference with the focus on women’s leadership: Finding your power, Moscow, ID 05/2018 WSU Transparent Assignment Design Workshop, Office of Assessment of Teaching & Learning, a half-day hands-on training on assignment design, WSU 04/2018 WSU Grant Writing Workshop, Office of Research Advancement and Partnerships (ORAP), a full-day hands-on & interactive grant writing exercise, WSU 04/2018 WSU & UI Women’s Leadership Conference, a full-day conference with the focus on women’s leadership: Lifting as we climb, Moscow, ID 10/2016 WSU Grant Writing Seminar, Grant Writers’ Seminars & Workshops LLC, a full- day workshop, Moscow, ID 05/2014 Writing and Publishing a Scientific Paper, a 4-week (12-hr) course on writing the manuscript, choosing the right journal, and learning the publishing process, NIH/NIEHS, RTP, NC

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05/2014 Scientists Teaching Science, 9-week (18-hr) online course on best practices in science education based on the latest research on teaching and learning, NIH/NIEHS, RTP, NC 03/2014 NIEHS Grant Writing Seminar, Grant Writers’ Seminars & Workshops LLC, a 1- day class offered to fellows on how to Write Winning NIH Grant Proposals, NIH/NIEHS, RTP, NC 01/2013 NIEHS Teaching College Course, a 10-week (20-hr) course designed to prepare postdoctoral fellows for teaching careers, NIH/NIEHS, RTP, NC

LAB/RESEARCH IN THE NEWS

05/2021 Highlighted in the Society for the Study of Reproduction Weekly News 03/2021 Featured on #WSUFacultyFriday 01/2020 Research focus highlighted in The Daily Evergreen 01/2020 Extramural funding from NIH featured in WSU News 10/2019 WSU Office of Research recognition for the largest new individual grant award for FY 2019 04/2017 Research featured in WSU News, phys, sciencedaily, Pacific Reproductive Center, Visible Embryos: “Fertility can hinge on uterus swimming conditions” 02/2017 Research featured in STATNEWS: “From ovary to uterus: studying the overlooked transport in between” 08/2016 WSU news: “Student research, retention thrive with team mentoring”

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