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EAACI Course

Update and new concepts in basic and translational Saturday, 1 June 2019

08:30-14:00 hrs Room Hall 2 (Altice Arena)

Introduction to the immune system Abul K. Abbas (United States)

Innate immunity Abul K. Abbas (United States)

Break

Antigen presentation, T cell activation and costimulation Abul K. Abbas (United States)

CD4 T cell subsets, cytokines Abul K. Abbas (United States)

B cells and Abul K. Abbas (United States)

Break

Immune regulation and tolerance Abul K. Abbas (United States)

Immunologic complications of cancer immunotherapy Abul K. Abbas (United States)

EAACI/UEMS Exam

12th EAACI/UEMS Knowledge and Pediatric Examination in Allergology and Clinical Immunology Saturday, 1 June 2019

11:00-14:00 hrs Room Hall 8 (FIL Meeting Centre)

Food > Pediatrics > Allergy diagnosis and systems medicine > Precision Medicine

Luso-Brazilian Day

Luso-Brazilian Symposium: XVIII Meeting of the Luso-Brazilian Society of Allergy and Clinical Immunology (SLBAIC): – clinical highlights Saturday, 1 June 2019

14:00-15:30 hrs Room Hall 5 (Altice Arena)

Chairs Dirceu Solé (Brazil) Rodrigo Rodrigues Alves (Portugal)

Molecular diagnosis in food allergy Renata Rodrigues Cocco (Brazil)

Tolerance induction in food allergy Alexandra F. Santos (United Kingdom)

Eosinophilic gastrointestinal disorders Ana Célia Costa (Portugal)

Question and answers

Nutritional evaluation of patients with successful oral immunotherapy: A strongly recommended procedure Bruna Pultrini Aquilante (Brazil)

Does introduction of baked milk products increase tolerance to milk proteins in milk-allergic children? Ana Luísa Moura (Portugal)

Allied health and primary care

Allied Health Day

Allied Health Day Achieving competencies for allied health and primary care professionals working in a clinical allergy setting Saturday, 1 June 2019

14:00-17:30 hrs Room Hall 4 (Altice Arena)

Chairs James Gardner (United Kingdom) Radoslaw Gawlik (Poland)

Welcome and introduction

The immune system and pathways of allergic reactions Sébastien Lefevre (France)

Epidemiology and risk factors for allergic disease including prevention Inger Kull (Sweden)

Break and visit to clinical village

Competencies for AHP in allergy James Gardner (United Kingdom)

Community allergy clinics whats possible? Radoslaw Gawlik (Poland)

The role of the MDT and the impact of allergy on quality of life Emilia Vassilopoulou (Cyprus)

Closing remarks Drug allergy > Pediatrics > Allergy diagnosis and systems medicine > Clinical Allergology

Interactive Postgraduate Courses (IPGC)

IPGC 1 Management of drug in children – Basic Saturday, 1 June 2019

14:00-17:30 hrs Room Fernando 1-2 (Altice Arena)

Chairs Cristobalina Mayorga (Spain) Knut Brockow (Germany)

When should you suspect a drug allergy in children? Marina Atanaskovic-Markovic (Serbia)

When should skin test and/or drug provocation test be included in the diagnosis of drug allergy in children? Jean-Christoph Caubet (Switzerland)

Break and visit to clinical village

When should in vitro testing be included in the diagnosis of drug allergy in children? Cristobalina Mayorga (Spain)

Drug provocation test versus drug desensitization Josefina Maria Rodrigues Cernadas (Portugal)

Mast cell disease and drug in children Knut Brockow (Germany)

Allergen immunotherapy

Interactive Postgraduate Courses (IPGC)

IPGC 2 immunotherapy – Basic Saturday, 1 June 2019

14:00-17:30 hrs Room Auditorium III (FIL Meeting Centre)

Chairs Lars Jacobsen (Denmark) Adam M Chaker (Germany)

Immunotherapy for rhinitis and asthma Jasper Kappen (The Netherlands)

How to identify responders and non-responders in clinical trials: Is it the same in clinical practice? Adam M Chaker (Germany)

How to deal with placebo effect in clinical trials and in clinical practice Lars Jacobsen (Denmark)

Break and visit to clinical village

Immune mechanisms and biomarker oof SLIT and SCIT: Are they similar? Mohamed Shamji (United Kingdom) EAACI guidelines on allergen immunotherapy: Allergic rhinoconjunctivitis Oliver Pfaar (Germany)

Allergy diagnosis and systems medicine

Interactive Postgraduate Courses (IPGC)

IPGC 3 Implementing molecular allergology and cellular testing in allergy diagnostics 2019 – Advanced Saturday, 1 June 2019

14:00-17:30 hrs Room Hall 3 (Altice Arena)

Chairs Edward Frank Knol (The Netherlands) Stephanie Dramburg (Germany)

Implementing component research diagnostics in allergy diagnosis Jörg Kleine-Tebbe (Germany)

Molecular profiling of allergic patients by multiplex testing Paolo Matricardi (Germany)

Break and visit to clinical village

Cellular tests for the diagnosing and monitoring of allergy Edward Frank Knol (The Netherlands)

Practical guide to using allergen micro array Olga Luengo (Spain)

Food allergy

Interactive Postgraduate Courses (IPGC)

IPGC 4 Non-IgE mediated food allergy - Basic Saturday, 1 June 2019

14:00-17:30 hrs Room Hall 7 (Altice Arena)

Chairs Rosan Meyer (United Kingdom) Stephanie A. Leonard (United States)

Worldwide epidemiology and natural history Yizhak Katz (Israel)

How to diagnose? Stephanie A. Leonard (United States)

Break and visit to clinical village

Differential diagnosis with clinical cases Antonella Cianferoni (United States)

Management: Multiple vs. single FPIES Rosan Meyer (United Kingdom) Interactive Postgraduate Courses (IPGC)

IPGC 5 Practical management of IgE-mediated food allergy - Basic Saturday, 1 June 2019

14:00-17:30 hrs Room Pessa 4-6 (Altice Arena)

Chairs Simona Barni (Italy) Inês Pádua (Portugal)

Risk assessment and active management of food allergy Maeve M. Kelleher (United Kingdom)

Allergen avoidance and precautionary allergen labelling Nicolette Wilma de Jong (The Netherlands)

Alternative free-from foods to reach a balanced diet Kate Grimshaw (United Kingdom)

Break and visit to clinical village

Nutritional deficiencies and impact on growth Inês Pádua (Portugal)

Current and novel therapeutically approaches for food allergy Simona Barni (Italy)

Biologicals > Basic Allergology > Clinical Immunology > Precision Medicine

Interactive Postgraduate Courses (IPGC)

IPGC 6 Understanding Immunological pathways of the new biological therapies - Advanced Saturday, 1 June 2019

14:00-17:30 hrs Room Hall 6 (Altice Arena)

Chairs Onur Boyman (Switzerland) Oscar Palomares (Spain)

What happens if you block IgE? Oscar Palomares (Spain)

What happens if you block IL-5? Apostolos Bossios (Sweden)

Break and visit to clinical village

What happens if you block IL-4/IL-13? Onur Boyman (Switzerland)

What happens if you block IL-33 or TSLP Thomas Eiwegger (Canada)

Basic Immunology > Basic Allergology > Biologicals > Precision Medicine Interactive Postgraduate Courses (IPGC)

IPGC 7 Big data revolution- integrating various omics datasets - Advanced Saturday, 1 June 2019

14:00-17:30 hrs Room Fernando 3-4 (Altice Arena)

Chairs Domingo Barber (Spain) Claudia Traidl-Hoffmann (Germany)

Understanding next generation sequencing through gene ontologies and user-friendly platforms Milena Sokolowska (Switzerland)

Studying miRNA: From biomarker characterization to novel therapeutic targets Ana Rebane (Estonia)

Break and visit to clinical village

Metabolomics in allergy research Alma Villaseñor Solis (Spain)

Microbiome analysis beyond 16S sequencing Claudia Traidl-Hoffmann (Germany)

Asthma > Clinical Allergology > Environmental and occupational allergy

Interactive Postgraduate Courses (IPGC)

IPGC 8 Bronchial provocation challenges for diagnosing exercise-induced asthma in adults - Basic Saturday, 1 June 2019

14:00-17:30 hrs Room Pessa 1-3 (Altice Arena)

Chairs Matteo Bonini (Italy) Joaquin Sastre (Spain)

The role of exercise challenge test among regular asthmatic individuals for diagnosis and for training prescription Mariana Couto (Portugal)

Protocols for exercise challenges in athletes - standardized according to the sport practiced? Matteo Bonini (Italy)

Break and visit to clinical village

Eucapnic voluntary hyperventilation – pitfalls and benefits Joaquin Sastre (Spain)

Mannitol bronchial challenge: Useful or not for the regular patient and for the professional athlete? Maia Rukhadze (Georgia)

Clinical Village Clinical Village Saturday, 1 June 2019

14:00-18:00 hrs Room Altice Arena

Luso-Brazilian Day

Break Saturday, 1 June 2019

15:30-16:00 hrs Room Hall 5 (Altice Arena)

Asthma

Luso-Brazilian Day

Luso-Brazilian Symposium: XVIII Meeting of the Luso-Brazilian Society of Allergy and Clinical Immunology (SLBAIC): Asthma phenotypes Saturday, 1 June 2019

16:00-17:30 hrs Room Hall 5 (Altice Arena)

Chairs Ana Morête (Portugal) Nelson Rosario (Brazil)

Pediatric asthma Gustavo Wandalsen (Brazil)

Adult asthma Mario Morais-Almeida (Portugal)

Asthma in the elderly Norma Rubini (Brazil)

Questions & Answers

Identification of asthma phenotypes in the US general population: A latent class analysis approach Rita Amaral (Portugal)

Tidal changes in respiratory reactance are sensitive indicators of airway obstruction in severe asthma JOSEANE CHIABAI (Brazil)

Luso-Brazilian Day

Interactive Poster Discussions: Asthma Saturday, 1 June 2019

17:30-18:15 hrs Room e-Poster Station 1 in Hall 5 (Altice Arena) Chairs Mariana Couto (Portugal) Gustavo Wandalsen (Brazil)

Human volatilome analysis using ENose to assess uncontrolled asthma in a clinical setting Mariana Valente Farraia (Portugal)

Clinical characteristics of patients with AERD and eligibility for therapy with monoclonal in a Brasilian cohort Gabriella Melo Fontes Silva Dias (Brazil)

Dietary acid load: A novel nutritional target on the children’s obese-asthma phenotype? Pedro Cunha (Portugal)

Particulate matter and asthma: Effect modification by tumor necrosis factor-a polymorphisms in lung function Albertina Varandas Capelo (Brazil)

Visceral adiposity is associated with cytokines and decrease in lung function in women with persistent asthma Albertina Varandas Capelo (Brazil)

Clusters of asthma control: Data from the Portuguese inspirers studies Cristina Jácome (Portugal)

Comorbidities and asthma severity in a brazilian cohort of patients Luane Marques Mello (Brazil)

Severe asthma questionnaire: Translation to portuguese and cross-cultural adaptation for use in Portugal Bárbara Kong Cardoso (Portugal)

Luso-Brazilian Day

Interactive Poster Discussions: Food Allergy Saturday, 1 June 2019

17:30-18:15 hrs Room e-Poster Station 2 in Hall 5 (Altice Arena)

Chairs Ana Célia Costa (Portugal) Dirceu Solé (Brazil)

House dust mite in : A confusing factor in shrimp allergy José Roberto Mendes Pegler (Brazil)

Nine-year survey of anaphylaxis in an allergy department Ângela Gaspar (Portugal)

What a restaurant staff knows about food allergy? - Impact of a face-to-face training course Inês Pádua (Portugal)

LTP’s sensitization – a 5 year follow up study Inês Sangalho (Portugal)

Peanut allergy: Co-sensitization, co-allergy, and tolerance to tree nuts Maria Luís Marques (Portugal)

Prevalence of self reported food allergy in adults at a federal university in Niteroi, Brazil Jose Laerte Boechat (Brazil)

Contribution of molecular diagnosis in the prognosis of egg tolerance acquisition Sara Patrícia Carvalho (Portugal)

Profilin sensitization – a review of 5 years follow up in an allergy department Inês Sangalho (Portugal) Opening Ceremony

Opening Ceremony Saturday, 1 June 2019

19:00-20:30 hrs Room Hall 1 (Altice Arena)

JMA Poster Sessions

JMA P01 Air pollution, environmental , prevention and risk factors Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 1 in FIL Meeting Centre

Chairs Carmen Galán (Spain) Magna Alves-Correia (Portugal)

Swimming pool training environment may drive skin and gut dysbiosis in elite swimmers Inês Ribeiro Paciência (Portugal)

Molecular sensitisation profile to Dermatophagoides pteronyssinus dust mite in Portugal Rita Limão (Portugal)

Modification of effect between air pollution and lung function by the inflammatory potential of diet: A cross sectional study in children Francisca De Castro Mendes (Portugal)

Effects of air pollutants on pulmonary function in children monitoring by mobile phone application I-Jen Wang Wang (Taiwan)

Loading of beta-lactoglobulin confers cross-protection against sensitization to the major allergen Bet V 1 in a BALB/c mouse model Franziska Roth-Walter (Austria)

Allergic sensitization in veterinary medicine students Ana Margarida Mesquita (Portugal)

The effect of triclosan exposure on the development of allergic diseases I-Jen Wang Wang (Taiwan)

Does grandmother’s smoking influence asthma risk in the grandchild? A systematic review and meta-analysis Guo-Qiang Zhang (Sweden)

Fracture risk reduction by bisphosphonates in mastocytosis Merel C. Onnes (The Netherlands)

Allergic sensitization profiles in immigrant population Francisca Vílchez Sánchez (Spain)

Flour sensitization in a factory of wooden doors - what is the relationship? Joana Queirós Gomes (Portugal)

Prevalence of allergic diseases in adolescents according to gender Cristine Secco Rosario (Brazil)

Evaluation of hypersensitivity reactions to cancer chemotherapeutic agents in childhood Irem Turgay Yagmur (Turkey)

JMA Poster Sessions JMA P02 Allergy diagnosis/systems biology/personalised medicine/omics Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 2 in FIL Meeting Centre

Chairs Victoria Cardona (Spain) Leticia De las Vecillas Sánchez (Spain)

Correlation between nasal provocation test, skin reativity and specific IgE to dermatophagoides pteronyssinus and lepidoglyphus destructor Sofia Martins Farinha (Portugal)

Autophagy in vernal keratoconjunctivitis and the role of TNF-alpha Rocco Luigi Modugno (Italy)

Modulation of the myeloid arachidonic acid metabolism imparts helminth-driven control of type 2 inflammation Antonie Friedl (Germany)

The role of gene polymorphisms and serum levels of growth factors in the immunopathogenesis of atopic diseases in children Olga Semernik (Russia)

Clinical relevance of dermatophagoides pteronyssinus sensitization in patients with rhinitis Sofia Martins Farinha (Portugal)

MicroRNA, a biomarker for I-Jen Wang Wang (Taiwan)

Analytical performance of a new chemiluminescent singleplex IgE assay Ekaterina Potapova (Germany)

RNA sequencing revealed transcriptomic changes of the human nasal epithelium following human influenza infection Kai Sen Tan (Singapore)

Method development for allergen capture from allergenic sources using human IgE-antibodies Julia Klueber (Luxembourg)

Production of nature-identical Bet V 1 and Ara H 2 using a plant-based transient expression system Öykü Üzülmez (Turkey)

Phenotypes diagnosis of allergic rhinitis using nasal provocation test Natalia Aliakhnovich (Belarus)

Cell-penetrating peptide dendrimers as multifunctional therapeutic agents Ksenia Kozhikhova (Russia)

An nasal secretion preparation method: Paving an effective way for noninvasive local IgE measurement Feng Lan (China)

Pattern of sensitization to common aeroallergens in the north of portugal: Four-year evaluation of an allergy center of a university hospital Maria João Vasconcelos (Portugal)

JMA Poster Sessions

JMA P03 Anaphylaxis and Drug Allergy Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 3 in FIL Meeting Centre

Chairs Alberto Alvarez-Perea (Spain) Alessandra Arcolaci (Italy)

Escuadra study: Spanish multicenter study about the use of epineprhine autoinjectors by allergic patients Laura Argiz (Spain)

The global incidence and prevalence of anaphylaxis in children in the general population: A systematic review Yichao Wang (China)

Strongly positive basophil activation with gelatin-containing vaccines for varicella, zoster, measles, mumps and rubella in patients with alpha-gal syndrome Paul Schmidle (Germany)

Diagnostic testing for penicillin allergy: Practices and cost perceptions in Europe and North America Bernardo Sousa-Pinto (Portugal)

B cell proliferation assay unravels amoxicillin allergy Marcello Albanesi (Italy)

Perioperative anaphylaxis in children: Etiology, time sequence and patterns of reactivity Ekaterina Khaleva (United Kingdom)

Do pharmacists know how to use adrenaline autoinjectors? Ricardo Moço Coutinho (Portugal)

Diagnostic value of serum CCL2 in anaphylaxis Romana Vantur (Slovenia)

Profile of 15 patients with food dependent exercise induced anaphylaxis from India Karthik Nagaraju (India)

What should the ideal adrenaline auto-injector needle length be? Murat Türk (Turkey)

Evaluation of venom allergy, anaphylaxis and adrenaline auto-injector knowledge level in turkish beekeepers and their family members Zeynep Hizli Demirkale (Turkey)

Diagnostic accuracy of skin tests in patients with a penicillin allergy label: A systematic review with meta-analysis and meta-regression Bernardo Sousa-Pinto (Portugal)

JMA Poster Sessions

JMA P04 Asthma 1 Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 4 in FIL Meeting Centre

Chairs Matteo Bonini (Italy) Pasquale Comberiati (Italy)

Metabolic characterization of epithelial barrier damage caused by Der P 1 Alma Villaseñor Solis (Spain)

Dysregulation of sphingolipid metabolic pathways identified by untargeted metabolomics in patients with aspirin exacerbated respiratory disease Ga young Ban (South Korea)

House dust mite priming enhances rhinovirus-induced inflammasome activation in asthma Urszula Radzikowska (Switzerland)

A mobile telephone-based interactive self-care system may improve asthma quality of life I-Jen Wang Wang (Taiwan) Asthma may increase the risk of non small cell carcinoma I-Jen Wang Wang (Taiwan)

Distinct HDM (House Dust Mite) -mediated “asthma” phenotypes in 4 mouse strains - partly associated with differences in microbial populations detected in the lungs Barbara Hammer (Germany)

Dysregulation of NLRP3 inflammasome pathways in patients with severe asthma Efthymia Theofani (Greece)

Dietary acid load: A novel nutritional target on the children’s obese-asthma phenotype? Pedro Cunha (Portugal)

Mild maternal smoking regulates gene expression in CD8 SP Thymic T cells in prenatally exposed murine offspring Barbara Hammer (Germany)

Identification of asthma phenotypes in the US general population: A latent class analysis approach Rita Amaral (Portugal)

Asthma and severe obesity: Glucocorticoid sensitivity before and after bariatric surgery Marina Bantulà Fonts (Spain)

Nonallergic asthma, allergic asthma and nonasthmatic respiratory allergy: Definition of discriminatory biomarkers and their epigenetic modulation Selene Baos (Spain)

PAH exposure, DNA methylation, and childhood atopic disorders I-Jen Wang Wang (Taiwan)

The effect of SERPINB1 protease inhibitor on the inflammatory response genes in bronchial epithelial cells Dilara Karaguzel (Turkey)

JMA Poster Sessions

JMA P05 Asthma 2 Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 5 in FIL Meeting Centre

Chairs Mattia Giovannini (Italy) Cristina Boccabella (Italy)

The burden of pediatric asthma. First results of the gan study in mexico Nayely Reyes Noriega (Mexico)

Role of osteopontin in late-onset asthma Tu Hoang Kim Trinh (Viet Nam)

Causes behind admission to pediatric intensive care unit (PICU) in asthmatic patients in Qatar Mehdi Adeli (Qatar)

Effects of tobacco smoking on the murine lung and gut microbiome Draginja Kovacevic (Germany)

Risk factors for reduced lung function after first wheezing episode: 7-year follow-up Ida Strengell (Finland)

Severity of allergic asthma associated with sensitization to food Raisa Borges Castro (Brazil)

Effect of 6-gingerol on CD4+ T-Helper (Th2) immune response and airway remodeling in mouse model of house dust mite (HDM)-induced asthma Babajide Oluwaseun Ajayi (Nigeria)

MiRNAs signature in serum: A biomarker for differentiation of asthma against ACO and COPD José Manuel Rodrigo-Muñoz (Spain)

Human volatilome analysis using ENose to assess uncontrolled asthma in a clinical setting Mariana Valente Farraia (Portugal)

MicroRNA, environmental exposures, and asthma I-Jen Wang Wang (Taiwan)

Longitudinal profiling of immunoglobulin heavy-chain repertoires in memory B-cells, plasmablasts and plasma cells from peripheral blood of individuals with birch pollen allergy Artem Ilyich Mikelov (Russia)

Systemic inflammation in asthmatic patients is related to age and airway obstruction Joanna Jamroz-Brzeska (Poland)

Comparison of the oxidative stress response induced by tert-butyl hydroperoxide in airway resident and inflammatory cells Dilara Karaguzel (Turkey)

JMA Poster Sessions

JMA P06 ENT and Dermatology Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 6 in FIL Meeting Centre

Chairs Peter Valentin Tomazic (Austria) Charlotte G. Mortz (Denmark)

Topographical diversity of the upper respiratory tract microbiome in chronic rhinosinusitis patients Katleen Martens (Belgium)

Impaired endothelial function in mastocytosis correlates with disease severity Roberta Parente (Italy)

Broad immunglobulin G repertoire in chronic rhinosinusitis with nasal polyps regulates pro-inflammatory IgE responses Janice Anastasia Layhadi (United Kingdom)

Eczema and urticaria in the adult population in Portugal: A prevalence study Daniela Fernandes Carvalho (Portugal)

The efficacy and safety of the up-dosing of second-generation H1 in treatment of chronic spontaneous urticaria in a paediatric population Lucrezia Sarti (Italy)

Integration of high-dimensional -omics reveals novel predictive signatures and candidate pathways for allergic rhinitis (AR) Anand Kumar Andiappan (Singapore)

Short exposures and glove protection from (meth)acrylates in nail beauticians – thoughts on a rising concern Francisca Jácome Morgado (Portugal)

Real-life assessment of chronic rhinosinusitis patients using mobile technology Sven F Seys (Belgium)

Association of the CD14 (-159C/T) SNP with house dust mites sensitization in patients with perennial allergic rhinitis in the population of ukraine Taras Petrovych Baranovskyi (Ukraine)

A systems biology approach to model complex respiratory diseases (asthma and respiratory allergy): Evaluation and prioritization of potential molecular biomarkers María de los Ángeles De Pedro (Spain)

Autologous serum skin test and basophil activation test: Are the same or different phenomena? Lobna Abdelaziz El-Korashi (Egypt)

The need for individually tailored prophylaxis with C1-INH concentrate in pediatric patients with hereditary (HAE) – real life data Inmaculada Martinez Saguer (Germany)

JMA Poster Sessions

JMA P07 Food allergy and digestive system 1 Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 7 in FIL Meeting Centre

Chairs Simona Barni (Italy) Alexandra F. Santos (United Kingdom)

Peanut allergy: Co-sensitization, co-allergy, and tolerance to tree nuts Maria Luís Marques (Portugal)

Are schools banning nuts? Results from a population-based survey of Australian schools Vicki Mcwilliam (Australia)

Functional and phenotypic analysis of allergen-specific B cells in cow’s milk allergy and tolerance Pattraporn Satitsuksanoa (Switzerland)

The novel long-acting IgETrap-Fc fusion protein GI301 elicits therapeutic synergy in combination with probiotics for the treatment of food allergy Bo Gie Yang (South Korea)

Kinetics of activation of peanut-specific effector and regulatory CD4+ T cells Daniel Lozano-Ojalvo (Spain)

Spanish children with acute FPIES usually tolerate all other food groups Laura Argiz (Spain)

The role of usability in digitized nutritional counselling settings Janina Sauer (Germany)

Oral immunotherapy with egg peptides induces innate and adaptive tolerogenic responses MÓNICA MARTÍNEZ BLANCO (Spain)

House dust mite in atopy: A confusing factor in shrimp allergy José Roberto Mendes Pegler (Brazil)

Egg yolk acts as adjuvant activating innate immune responses to egg white allergens in BALB/C MICE Daniel Lozano-Ojalvo (Spain)

Correlation between intestinal barrier dysfunction and epigenetic activation of atopy in children with food hypersensitivity skin symptoms Olga Pakholchuk (Ukraine)

Basophil and mast cell responses to food allergens in sensitised but tolerant patients are not mediated via the FcgRIIa and FcgRIIb receptors Richard Thomas McKendry (United Kingdom)

The potential immunomodulatory activity of titanium dioxide and other food and drug dyes Natalia Aliakhnovich (Belarus)

JMA Poster Sessions

JMA P08 Food allergy and digestive system 2 Saturday, 1 June 2019 20:30-21:45 hrs Room e-Poster Station 8 in FIL Meeting Centre

Chairs Olympia Tsilochristou (United Kingdom) Giovanni Battista Pajno (Italy)

IgE to epitopes of Ara H 2 enhance the diagnostic accuracy of Ara H 2-Specific IgE Oliver Hemmings (United Kingdom)

IgE-reactive proteins defined by 88 fish-allergic children, predicting the allergenicity of 66 asia-pacific fish species Thimo Ruethers (Australia)

Deep remission in : Looking beyond eosinophils Larissa de Queiroz Mamede (Brazil)

Allergenicity and cross-reactivity of different variants of the peanut allergen Ara H 2 Anniek van de Velde (Denmark)

Negative phychosocial effect of dietary elimination on breastfeeding mothers having infants with and without food allergy Ozlem Yilmaz (Turkey)

Epitope-specific antibody binding on major Hen’s egg-white allergen, ovomucoid, using novel multiplex immunoassay Maria Suprun (United States)

Eosinophilic esophagitis: Association with atopic diseases and IgE mediated food allergy Pablo Torres (Ecuador)

Low molecular weight components from fish modify physical and immunological properties of the bronchial epithelium Tanja Kalic (Austria)

Metabolic profile of a murine model of allergic enteritis Elisa Violeta Zubeldia-Varela (Spain)

Shrimp sensitization in house dust mite allergic patients Natalia Ewa Ukleja-Sokolowska (Poland)

Do threshold data from food challenges reflect real-life allergen exposure? Olaya Alvarez Garcia (Spain)

Breast milk fatty acid composition of allergic and non-allergic mothers: The ulm SPATZ health study Linda Siziba (Germany)

Molecular restoration in eosinophilic esophagitis patients after treatment with proton-pump inhibitors José Antonio Cañas (Spain)

JMA Poster Sessions

JMA P09 Immunotherapy and Immunology 1 Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 9 in FIL Meeting Centre

Chairs Carmen Riggioni (Spain) Mohamed Shamji (United Kingdom)

ELKS controls mast cell degranulation by regulating the chromatin context of syntaxin 4 Hiu Yan Lam (Singapore)

Repeated exposure to house dust mite drives persistent activation of inflammatory macrophages Antonie Friedl (Germany) MiR-8485 is locally upregulated upon allergen-specific immunotherapy and coincides with shifted Breg/Th17 balance Constanze A. Jakwerth (Germany)

Cyclic immunologic changes of maintenance phase subcutaneous immunotherapy in house dust mite allergy Nada Chaoul (Lebanon)

Unbiased mass cytometry analysis method applied to high-dimensional single cell phenotyping deciphers tolerance induction in a model of allergen immunotherapy Guillem Montamat (Luxembourg)

A novel toll-like receptor 7 agonist can ameliorate phleum pratense induced allergic responses in vitro Max Kirtland (United Kingdom)

Pilot study to determine effect of feeding cat food made with egg product containing Anti- Fel D1 antibodies to cats on human allergy symptoms James D Wedner (United States)

Feeding Anti-Fel d1 chicken antibodies decreases active Fel d1 on cat hair Ebenezer Satyaraj (United States)

Distinct microRNA expression patterns after IL-33 challenge in murine lung and bone marrow Emma Winberg (Sweden)

MiR-155-5p, MiR-26-3p and MiR-29-5p/3p serum levels are decreased in human anaphylaxis Emilio Núñez-Borque (Spain)

Assessment of pre-clinical blocking activity of a hypoallergenic birch pollen vaccine candidate Lorenz Aglas (Austria)

Immunomodulatory properties of lolium perenne peptides for the treatment of seasonal allergic rhinitis Janice Anastasia Layhadi (United Kingdom)

The rate of adverse events is comparable between simultaneous and vespid venom immunotherapy and bee venom mono-immunotherapy Urban Cerpes (Austria)

JMA Poster Sessions

JMA P10 Immunotherapy and Immunology 2 Saturday, 1 June 2019

20:30-21:45 hrs Room e-Poster Station 10 in FIL Meeting Centre

Chairs Florentina Sava (United Kingdom) Oscar Palomares (Spain)

Characterization of the sensitization profile of honeybee sting allergic patients Catarina Pereira Coutinho (Portugal)

Feasibility of studying the changes in relative distribution of allergen specific antibody isotypes overtime David Obeso (Spain)

BCG vaccine-associated complications and clinical course following allogeneic bone marrow transplantation in patients with primary immunodeficiency diseases Adeeb Nasser Eldin (Palestine)

Safety of a five-step versus a six-step ultra-rush venom immunotherapy protocol Ricardo Moço Coutinho (Portugal)

A novel Pru p 3 sublingual immunotherapy ultra-rush protocol Ana Luísa Moura (Portugal)

Carbohydrate-protein conjugates for allergen-specific immunotherapy Evgeniia Korotchenko (Austria) Severe respiratory allergic patients undergo remodelling prior to food allergy Javier Sanchez Solares (Spain)

Autoimmunity and lymphoproliferation: Different or converging phenotypes in common variable immunodeficiencies? Cláudia Viseu Varandas (Portugal)

Neutrophils promote allergic inflammation by presenting allergen to specific CD4+ T-cells Dominika Polak (Austria)

Bacterial cell wall fragment glucosaminyl muramyl dipeptide in treatment of allergic disease Svetlana Guryanova (Russia)

Welcome Reception

Welcome Reception Saturday, 1 June 2019

20:30-23:00 hrs Room FIL Main Entrance

Biologicals > Pediatrics

Learning Lounges (LL)

LL 1 Decision making in prescribing biologicals in children Sunday, 2 June 2019

07:30-08:15 hrs Room Hall 11 (FIL)

Decision making in prescribing biologicals in children Susan Chan (United Kingdom)

Allergen immunotherapy

Learning Lounges (LL)

LL 2 Allergen immunotherapy – Basic and clinical perspective Sunday, 2 June 2019

07:30-08:15 hrs Room Hall 12 (FIL)

Allergen immunotherapy – Basic and clinical perspective Mohamed Shamji (United Kingdom)

Food allergy

Learning Lounges (LL) LL 3 Managing allergy Sunday, 2 June 2019

07:30-08:15 hrs Room e-Poster Area A (FIL)

Managing nut allergy Helen A Brough (United Kingdom)

Basic Immunology > Basic Allergology

Learning Lounges (LL)

LL 4 What to consider when setting up allergy animal models Sunday, 2 June 2019

07:30-08:15 hrs Room e-Poster Area C (FIL)

What to consider when setting up allergy animal models Katrine Lindholm Bøgh (Denmark)

Food allergy > Basic Immunology > Basic Allergology > Environmental and occupational allergy

Plenary Symposia (PL)

PL 1 New concepts in food allergy Sunday, 2 June 2019

08:30-10:00 hrs Room Hall 1 (Altice Arena)

Chairs Ioana Octavia Agache (Romania) Helen A Brough (United Kingdom)

Immune tolerance: Perspective from the T cell side Marc Veldhoen (Portugal)

Exposome and food allergy Harald Renz (Germany)

Can food allergy be cured? Kari Christine Nadeau (United States)

Dermatology > Basic Allergology > Basic Immunology > Biologicals

Plenary Symposia (PL)

PL 2 New insights in skin hypersensitivity Sunday, 2 June 2019 08:30-10:00 hrs Room Hall 2 (Altice Arena)

Chairs Cezmi Akdis (Switzerland) Edward Frank Knol (The Netherlands)

Pathophysiology: Epidermal barrier and immune imbalance Thomas Bieber (Germany)

What is the impact of the microbiome on atopic Martin Glatz (Switzerland)

New treatments in the pipeline Kilian Eyerich (Germany)

Pediatrics > Clinical Allergology > Clinical Immunology > Environmental and occupational allergy

Thematic Symposia (TSYM)

TSYM 1 Learning from each other: Pediatric and adult allergists exchange Sunday, 2 June 2019

10:30-11:45 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Susanne Gabriele Lau (Germany) Norbert Karl Mülleneisen (Germany)

Pediatric immundeficiencies everyone should know Anna Sediva (Czech Republic)

Prevention in infants – an update Michael Perkin (United Kingdom)

Occupational allergies - what job shall I do if I am allergic? Monika Raulf (Germany)

Company Sponsored Symposia (CSS)

CSS 1 Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 5 (Altice Arena)

Basic Immunology > Basic Allergology > Clinical Allergology

Hot Topic Sessions (HT)

HT 1 Novel function of epithelial cells Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 10 (FIL)

Chairs Henry McSorley (United Kingdom) Stefanie Eyerich (Germany)

Tuft cells: Players in type 2 immune responses Stephan Loeser (United Kingdom)

Memory in epithelial progenitor cells Samantha Larsen (United States)

Goblet cells – drivers of immune tolerance Virginia Lysbeth Calder (United Kingdom)

Food allergy > Allergy diagnosis and systems medicine > Clinical Allergology

Interactive Workshops (IWS)

IWS 1 Diagnosis and clinical outcomes in food allergy and anaphylaxis Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 6 (Altice Arena)

Chairs Kirsten Beyer (Germany) Manuel Branco Ferreira (Portugal)

Component resolved diagnostics in food allergy Victoria Cardona (Spain)

Severity and management in food allergy and anaphylaxis Barbara Ballmer-Weber (Switzerland)

Allergen immunotherapy > Clinical Allergology > Asthma > Dermatology

Late Breaking Poster Discussion Sessions (LB PDS)

LB PDS 01 Immunotherapy and clinical outcomes Sunday, 2 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Ralph Mösges (Germany) Markus Ollert (Luxembourg)

LOU064: A highly selective and potent covalent oral BTK inhibitor with promising pharmacodynamic effects in skin Julian Storim

Safety and efficacy of epicutaneous immunotherapy for peanut allergic children with and without asthma Lars Lange (Germany)

Biological standardization of the Dactylis glomerata, Festuca pratensis, Lolium perenne, Phleum pratense and Poa pratensis allergen extracts: A phase II clinical trial Inma Buendia (Spain)

The AIT- adjuvants alum and MPLA as trigger for NET release in human neutrophils Jasmine Karacs

A prospective, multicentre, open, non-interventional study to evaluate the risk-benefit assessment in the updosing phase of a house dust mite specific subcutaneous immunotherapy Katrin Birkholz (Germany)

Study of impact of subcutaneous pre-seasonal tree and/or grass pollen immunotherapy (with MPL adjuvant) on patients with allergic rhinoconjunctivitis Samia Azmi (United Kingdom)

From mite allergen extracts to allergen products: Elucidation of the mite allergen spectrum Steffen Augustin (Germany)

Retinoic acid determines the allergenicity of the major birch pollen allergen Bet v 1 in vitro and in vivo Karin Hufnagl (Austria)

BAT as useful method for monitoring the effectiveness of specific allergen immunotherapy Monika Knoppová (Czech Republic)

Safety and effectiveness of a single multiallergen subcutaneous immunotherapy in polyallergic patients Mónica Ruíz García

Quality of life in patients with house dust mite-associated allergic rhinitis treated with 300IR house dust mite sublingual tablet: Results of a large multicentre clinical trial Thomas Casale (United States)

The effect of Vitamin D supplement on hous dust mite (HDM) sublingual immunotherapy (SLIT) in children with allergic rhinitis (AR) Yang Park (South Korea)

Api m 10 sensitivity prevalence among patients allergic to bee venom referred to tertiary center of venom immunotherapy excellence Marta Kolacinska-Flont (Poland)

Efficacy of a 300IR house dust mite tablet is consistent when evaluated by the proportion of symptom-controlled days: Results of a large randomised, double-blind placebo-controlled, multicentre trial Thomas Casale (United States)

Asthma > Precision Medicine

Oral Abstract Sessions (OAS)

OAS 01 Mechanisms and biomarkers in asthma Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 9 (FIL)

Chairs Domingo Barber (Spain) Oscar Palomares (Spain)

Session roadmap Domingo Barber (Spain)

Fixed airflow obstruction in presence of asthma is associated with elevated blood eosinophils Andrei Malinovschi (Sweden)

Nonallergic asthma, allergic asthma and nonasthmatic respiratory allergy: Definition of discriminatory biomarkers and their epigenetic modulation Selene Baos (Spain)

Dysregulation of sphingolipid metabolic pathways identified by untargeted metabolomics in patients with aspirin exacerbated respiratory disease Ga young Ban (South Korea) Allergen and rhinovirus (RV) regulation of PD-L1/PD1 in allergic asthma Julia Kölle (Germany)

House dust mite priming enhances rhinovirus-induced inflammasome activation in asthma Urszula Radzikowska (Switzerland)

Dietary nitrate supplementation increases fractional exhaled nitric oxide: Implications for the assessment of airway health in athletes Hayden Allen (United Kingdom)

Drug allergy > Allergy diagnosis and systems medicine

Oral Abstract Sessions (OAS)

OAS 02 Diagnosis of drug hypersensitivity Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 11 (FIL)

Chairs Marina Atanaskovic-Markovic (Serbia) Aleksandra Wardzynska (Poland)

Session roadmap Marina Atanaskovic-Markovic (Serbia)

Diagnostic testing for penicillin allergy: Practices and cost perceptions in Europe and North America Bernardo Manuel Sousa-Pinto (Portugal)

Cephalosporins allergy testing is recommended in patients with anaphylaxis to penicillins Alicia Gallardo Higueras (Spain)

Short and extended provocation tests have similar negative predictive value in non-immediate hypersensivity to beta-lactams in children Frederico S. Regateiro (Portugal)

Immediate hypersensitivity to iodinated contrast media: Interest of intravenous challenge test with low dose in addition of skin-testing Sébastien Lefevre (France)

Tryptase determination as a complementary criterion for the diagnosis of perioperative anaphylaxis Joana Vitte (France, Metropolitan)

Severe cutaneous adverse drug reactions: Diagnostic approach Eduardo Costa (Brazil)

Pediatrics > Dermatology > Clinical Immunology > Biologicals

Oral Abstract Sessions (OAS)

OAS 03 Angioedema Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 12 (FIL)

Chairs Tabi Leslie (United Kingdom) Vera Mahler (Germany) Session roadmap Tabi Leslie (United Kingdom)

Acquired C1-inhibitor deficiency with recurrent angioedema: Spectrum and treatment with C1-inhibitor concentrate Konrad Bork (Germany)

Effects of long-term prophylaxis with subcutaneous C1 inhibitor in special patient populations: Findings from the COMPACT open-label extension trial Donald S. Levy (United States)

Final results from the ZENITH-1 study: Oral administration of plasma kallikrein inhibitor BCX7353 for the treatment of attacks in patients with hereditary angioedema Hilary J. Longhurst (United Kingdom)

GRK2 regulates the endothelial responsiveness to bradykinin: Role in C1- inhibitor- deficiency hereditary angioedema Jessica Gambardella (Italy)

Effects of subcutaneous C1-esterase inhibitor on coagulation and fibrinolysis in patients with hereditary angioedema: Findings from the COMPACT And OLE study Avner Reshef (Israel)

Angiotensin-converting enzyme inhibitor-associated angioedema in a cohort of Italian patients: From bed to bench Laura Carucci (Italy)

Allergen immunotherapy > Precision Medicine > Food allergy > Pediatrics

Oral Abstract Sessions (OAS)

OAS 04 Outcome measures in allergen and immunotherapy Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 13 (FIL)

Chairs Lars Jacobsen (Denmark) Stephen R Durham (United Kingdom)

Session roadmap Lars Jacobsen (Denmark)

Efficacy and safety of the 300 IR sublingual tablet for the treatment of house dust mite-associated allergic rhinitis: A multicentre, international, dbpc, randomized phase III clinical trial Thomas Casale (United States)

The SQ Tree SLIT-tablet provides significant improvement of nasal and ocular symptoms during the tree pollen season Adam M Chaker (Germany)

Treatment failure in bee venom immunotherapy: Too early to reach any conclusion regarding Api M 10 Lisa Arzt-Gradwohl (Austria)

The cambridge peanut allergy clinic: Real world safety and efficacy outcomes during oral immunotherapy with characterised peanut flour Andrew Clark (United Kingdom)

ARTEMIS: A European, phase 3, randomised, double-blind, placebo-controlled trial of AR101 in peanut-allergic children and adolescents aged 4-17 Montserrat Fernández-Rivas (Spain)

The SQ Tree SLIT-tablet improves quality of life for subjects with moderate-severe allergic rhinoconjunctivitis Ulf Darsow (Germany) Drug allergy

Poster Discussion Sessions (PDS)

PDS 01 Anaphylaxis and perioperative hypersensitivity Sunday, 2 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Ingrid Terreehorst (The Netherlands) Marta Ferreira Neto (Portugal)

Prescribed medications as risk factors for severe anaphylaxis John Desmond Molloy (Canada)

What are the sensitivity, specificity, positive and negative predictive values of skin tests to predict next perioperative anaphylaxis?: One center – three year experience Ceyda Tunakan Dalgiç (Turkey)

Association between severity of anaphylaxis and coexistence of cardiovascular diseases: A systematic review and meta-analysis of observational studies Martina Privitera Torres (Spain)

Relationship between new cases of anaphylaxis and use of angiotensin-converting enzyme inhibitors: A systematic review and meta-analysis of observational studies Sabela Pérez Codesido (Spain)

12 years nationwide registry of drug-induced anaphylaxis in Japan Chizuko Sugizaki (Japan)

Probable sevoflurane-induced perioperative anaphylaxis in a child: Case report Ekaterina Khaleva (United Kingdom)

Influence of demographic and clinical features on the severity of drug induced anaphylaxis Semra Demir (Turkey)

Evaluation of patients with nonsteroid antiinflammatory drug hypersensitivity: Anaphylactic reactions Müge Olgaç (Turkey)

Anaphylactic shock in NSAID context. Who is guilty, NSAID or food? Rocio Casas-Saucedo (Spain)

Basic Immunology > Basic Allergology

Poster Discussion Sessions (PDS)

PDS 02 Access to allergy via innate immunity Sunday, 2 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Ulrich Matthias Zissler (Germany) Milena Sokolowska (Switzerland)

NLRP3 inflammasome localized in the mitochondrial fractions contributes to LPS-induced neutrophilic pulmonary inflammation So Ri Kim (South Korea)

TLR2 + And TLR4 + Lymphocytes And Gp2, Spi-B, Nf-KB1, C-Rel, TNFa And TNFr gene activity in CALT rats in experimental diabetes mellitus and after administration of pentoxifylline Halyna Koval (Ukraine)

The impact of the interactions between airway epithelium, dendritic cells and macrophages on TSLP and IL-33 epithelial expression in asthma and healthy controls Magdalena Paplinska-Goryca (Poland)

Recombinant antígen 5 from polybia paulista wasp venom modulates the in vitro production of pro-inflammatory cytokines secreted by intraperitoneal macrophages from BALB/C mice Murilo Luiz Bazon (Brazil)

Investigation of the effects of tumor necrosis factor-alpha, H202, ethanol and butyrate on intestinal epithelial cell permeability Duygu Yazici (Turkey)

Dual-role of Bet V 1 ligands in the processing by endolysosomal proteases Wai Tuck Soh (Austria)

Allergooncology - IgG4 negatively influences the ADCP and drives macrophages to a regulatory phenotype: Implications for tumour-mediated immune tolerance Rodolfo Bianchini (Italy)

A7 nicotine acetylcholine receptor (NAChR) agonists strongly activate classical macrophages and increase the expression of HLA-DR molecules Andrei E Siniavin (Russia)

The influences of recombinant IFNa2b on the membrane CD16, CD66b, CD33, CD11b in non-transformed and in vitro experimental transformed neutrophilic granulocytes Irina Vadimovna Nesterova (Russia)

Age-dependent changes in circulating leukocytes from birth to adulthood in healthy and atopic subjects Anastasia Georgountzou (Greece)

Neutrophils promote allergic inflammation by presenting allergen to specific CD4+ T-cells Dominika Polak (Austria)

Progenitor cell-derived basophils: A novel passive degranulation assay in inhalant allergy testing Jiakai Wu (United Kingdom)

A systems biology approach to model complex respiratory diseases (asthma and respiratory allergy): Evaluation and prioritization of potential molecular biomarkers María de los Ángeles De Pedro (Spain)

Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity Kishor Dhaygude (Finland)

Allied health and primary care > Allergy diagnosis and systems medicine

Poster Discussion Sessions (PDS)

PDS 03 Improving the diagnosis and management of allergic diseases Sunday, 2 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Elizabeth Ann Angier (United Kingdom) Radoslaw Gawlik (Poland)

Development of a two-site ELISA for quantification of major dust mite allergen, Der P 23, in diagnostic and therapeutic products Bryan Smith (United States)

Is Pru p 3 a relevant test for lipid transfer protein allergy in a Northern European population? Helena Rey García (Spain)

Hypersensitivity symptoms for paracetamol over a decade in spontaneous reports to eudravigilance database Grzegorz Porebski (Poland)

Use of epinephrine in pediatric emergency departments depends on anaphylaxis severity Caroline Klingebiel (France)

Auto-injector administration results in rapid delivery and high peak plasma concentrations of epinephrine Margitta Worm (Germany)

What should the ideal adrenaline auto-injector needle length be? Murat Türk (Turkey)

Escuadra study: Spanish multicenter study about the use of epineprhine autoinjectors by allergic patients Laura Argiz (Spain)

Real world data of canadians living with hereditary angioedema: Part 3- treatment utilization William H Yang (Canada)

Multidisciplinary management of brazilian patients with hereditary angioedema: Impact on quality of life Sarah Sella Langer (Brazil)

Electronic registration of hereditary angioedema attacks unmask a higher severity of the disease Francesca Perego (Italy)

Evaluation Of Psychological Processes And Adaptation To The Disease In Adults With Hereditary Angioedema Due To C1 Inhibitor Deficiency: A Pilot Study From Italian Referral Centers Maria Bova (Italy)

Risk factors of high perceived stress in pregnant women from the preventADALL study Caroline-Aleksi Olsson Mägi (Sweden)

Interdisciplinary diagnosis and therapy of children with allergic diseases of the respiratory system Renata Agnieszka Zubrzycka (Poland)

Sister Society Symposia (SSS)

SSS 1 EAACI – AAAAI Joint Symposium: Advances in the evaluation and management of chronic urticaria Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 7 (Altice Arena)

Chair Timothy Craig (United States)

Update on management of antihistamine-resistant chronic urticaria Jonathan A Bernstein (United States)

Update on diagnosis and management of chronic inducible urticaria Marcus Maurer (Germany)

Reconciling differences in recommendations of JTFPP and EAACI/WAO urticaria guidelines David M Lang (United States)

Clinical Allergology > Asthma > Pediatrics > Allied health and primary care

Symposia (SYM) SYM 1 Influence of nutrition on allergic diseases Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 1 (Altice Arena)

Chairs Carina Venter (United States) André Moreira (Portugal)

Does diet diversity really matter? Kate Grimshaw (United Kingdom)

Dietary fatty acids are key to controlling allergic responses Eva Untersmayr (Austria)

When two worlds collide - The obese asthmatic Liam O'Mahony (Ireland)

ENT > Asthma > Clinical Allergology > Precision Medicine

Symposia (SYM)

SYM 2 Management of difficult chronic rhinosinusitis Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 2 (Altice Arena)

Chairs Valerie Hox (Belgium) Joaquim Mullol (Spain)

Steroids for rhinitis and rhinosinusitis: Good or bad? Philippe Gevaert (Belgium)

When is surgery needed? Claire Hopkins (United Kingdom)

New treatment strategies directed by endotyping Peter Hellings (Belgium)

Basic Immunology > Food allergy > Pediatrics > Allergen immunotherapy

Symposia (SYM)

SYM 3 Novel insights into B cell memory responses in allergy Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 3 (Altice Arena)

Chairs Rudolf Valenta (Austria) Mohamed Shamji (United Kingdom)

The role of B cells in the IgE memory Faruk Ramadani (United Kingdom) The perpetuation of IgE in anaphylaxis and food allergy Rodrigo Jiménez-Saiz (Spain)

Molecular aspect of regulatory B cells in allergy Mübeccel Akdis (Switzerland)

Basic Immunology > Clinical Immunology > Dermatology

Symposia (SYM)

SYM 4 The mast cell in health and disease Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 4 (Altice Arena)

Chairs Hanneke Oude Elberink (The Netherlands) Martin Church (United Kingdom)

Mast cells: Biology and diversity Martin Church (United Kingdom)

Mast cells, not only in allergy: From the bench to the bedside Yoseph Mekori (Israel)

Novel treatment modalities Sigurd Broesby-Olsen (Denmark)

Year in Review Sessions (YIR)

YIR 1 Year in Review: EAACI Journals Sunday, 2 June 2019

10:30-12:00 hrs Room Hall 14 (FIL)

Chairs Marek Jutel (Poland) Philippe Eigenmann (Switzerland)

The best of Allergy Heimo Breiteneder (Austria)

Recent highlights from PAI Ömer Kalayci (Turkey)

The best of CTA Clive Grattan (United Kingdom)

Drug allergy > Basic Immunology > Dermatology > Pediatrics

Late Breaking Thematic Poster Sessions (LB TPS) LB TPS 01 Drug hypersensitivity Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 6 in e-Poster Area A (FIL)

Chairs Eva Gomes (Portugal) Alessandra Arcolaci (Italy)

Allergy to low molecular weight heparins Diana Perez Alzate (Spain)

Safety and effectiveness of rapid desensitization in the management of hypersensitivity reactions to chemotherapeutic agents LETICIA SÁNCHEZ-MORILLAS

Investigation of piperacillin/tazobactam allergy in 48 patients Rosamund Sara Casimir-Brown

The utility of drug provocation tests in iodinated contrast media hypersensitivity Marta Pires Alves (Portugal)

Severe reaction after re-exposure to BLs support to re-evaluate allergic patients with clear histories but negative allergological studies María Ruano-Zaragoza (Spain)

Allergic reactions to topical lidocaine: Cases reports Vanesa Sánchez Moreno (Spain)

Evaluation of NSAIDs tolerance following Omalizumab treatment for chronic spontaneous urticaria Fernanda Casares Marcelino (Brazil)

Prevalence of registered penicillin allergy in primary care in the Netherlands Tina van der velde (The Netherlands)

Audit of ß-lactam drug challenges in a Tertiary Children’s Allergy Service and the outcomes of subsequent courses of antibiotics Julie Ann Pentland (United Kingdom)

Anaesthesia-associated hypersensitivity reactions Márcio André Mesquita (Portugal)

Progesterone hypersensitivity treated with a subcutaneous desensitization protocol Carolina Elduque Mora (Spain)

Seizing the moment: Benefits of immediate in-office penicillin oral challenge in the management of suspected penicillin allergy Vince Wu (Canada)

NSAID hypersensitivity: Experience from Vilnius University Hospital Santaros Klinikos Milda Dumciute

Cross reactivity to cephalosporins and carbapenems in penicillin allergic patients JAVIER SANCHEZ DE VICENTE

Immediate HyperSensitivity (IHS) to NSAIDs: Which Aspirin Challenge Test (ACT) for which patient? SARAH SROUR

Tolerance to Iopamidol in Iomeprol allergic patients JAVIER SANCHEZ DE VICENTE

The use of specific IgE, including specific IgE to penicillin minor determinants, in the diagnosis of penicillin allergy Sara Fransson (Sweden)

Basic Immunology > Clinical Immunology > Allergen immunotherapy Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 02 Immune mechanism in immunological diseases Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 12 in e-Poster Area B (FIL)

Chairs Umit Sahiner (Turkey) Kornel Golebski (The Netherlands)

Local skin infiltration of memory T cell clones in acute allergic contact dermatis includes nickel-specific CD4+ T cells identified in blood Katherina Siewert

Direct quantification of nickel-specific naïve and memory Th cells in peripheral blood of allergic and non-allergic donors Marina Aparicio-Soto

The French Side of the Global Angioedema Registry in 2019 Isabelle Gibod (France)

Potential immunomodulatory effect of the house dust mite microbiome Ju Yeong Kim (South Korea)

Hereditary angioedema with normal C1 Inhibitor with plasminogen (PLG) mutation: Phenotype characteristics of an additional five-generation affected family in the French cohort Isabelle Gibod (France)

Waldmann´s disease- a case report Magdalena Herknerova (Czech Republic)

Innate immune interactions of human rhinovirus-16 and grass pollen in grass pollen allergic adults Thina Kailaivasan (Australia)

Venom immunotherapy causes serum protein/peptide profiles changes Joanna Matysiak (Poland)

Altered protein expression patterns of Blattella germanica by antibiotics show decreased IgE reactivity with allergic patients. Seogwon Lee

Genetics variants in the TLSP locus here associated with eosinophilic esophagitis in Spanish population Robledo Ávila Castellano (Spain)

Genetics variants in the TLR3 locus are associated with eosinophilic esophagitis in Spanish population Robledo Ávila Castellano (Spain)

Identification of the major allergenic proteins of Bombyx mori moth’s wings Laura Araujo (Brazil)

The use of omalizumab for dermatologic manifestations of Hyper-IgE Syndrome – Two case reports Joana Miranda (Portugal)

Omalizumab Treatment in Children With Chronic Spontaneous Urticaria: Efficacy and Safety Melike Kahveci (Turkey)

Mucosa-associated epithelial chemokine, thymus expressed chemokine, periostin and zonulin levels in infants with atopic dermatitis Burcu Koksal (Turkey)

Vascular endothelial growth factor and interleukin-33 levels in children with recurrent wheeze Burcu Koksal (Turkey)

Food allergy > Pediatrics > Clinical Immunology Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 03 Food allergy Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 18 in e-Poster Area C (FIL)

Chairs Antonella Cianferoni (United States) Ana Célia Costa (Portugal)

Visual communication of allergens on food labels: A qualitative assessment André Moreira (Portugal)

Identification of hypoallergenic and nectarine cultivars by quantification of Pru p 3 content in 102 core peach collections Jing Jin (China)

Sensitization to Ana o 3 in tree nut and peanut allergy Lise Brosseron (Portugal)

Crustacean characterization: Identifying the seafood allergic patient, co-morbidities and associated atopic risk factors Tarin Moni (Canada)

Study of the effects of Pru p 3 sensitization in the MALT JAIME TOME AMAT

Identification and characterization of allergens Stefan Kabasser

Sensitization to cow milk components in children with different phenotypes and endotypes of food allergy Nelli Prikhodchenko (Russia)

Cross-reactivity in -dependent, exercise-induced allergy Miranda Smith

Profile of children with persistent peanut allergy María Vázquez De La Torre Gaspar (Spain)

Transplantation acquired egg and almond allergy in patient under tacrolimus immunosuppression Adolfo Sanchez Rodriguez

First report of monosensitivity to the Atlantic wolffish (Anarhichas lupus) Eva Ganseman (Belgium)

Component-resolved study in microarray format of cow milk and chicken egg white major allergen proteins in allergic patients in Moscow region, Russia Olga Stukolova

Food allergy profiles observed within ethnic group populations in West Birmingham and Sandwell, UK Gill Ashton

PIPE cloning: Fast production of human monoclonal IgG1, IgG4 and IgE antibodies specific for the major milk allergen beta-lactoglobulin Christina L Pranger (Austria)

Changes in skin prick-tests and serum specific IgE in patients under Cow´s Milk Oral Inmunotherapy (OIT): A 48 months follow-up evaluation Natalia Patricia Freundt Serpa

Clinical and serological characterization of a large cohort of red meat allergic patients from Sweden M. B. Gea Kiewiet (Sweden)

Basic Immunology > Clinical Immunology Thematic Poster Sessions (TPS)

TPS 01 Clinical immunology from autoimmunity to cancer Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 1 in e-Poster Area A (FIL)

Chairs Milena Sokolowska (Switzerland) Pedro Carreiro-Martins (Portugal)

The impact of serum anti-neutrophil cytoplasmic antibody (ANCA) on clinical presentation and outcome in pediatric onset systemic (SLE) patients chunchun gau (Taiwan)

Comparison of different methods in detection of antimitochondrial antibodies and their diagnostic utility Ceyda Tunakan Dalgiç (Turkey)

Comparison of different methods in detection of Anti-DsDNA antibodies and their diagnostic utility Ceyda Tunakan Dalgiç (Turkey)

Evaluate the frequency of autologous serum skin test in patients with autoimmune diseases Laís Souza Gomes (Brazil)

Therapeutic challenge regarding refractory idiopathic erythema nodosum - a case report Jorge Vaz Lourenço (Portugal)

The strange case of an anti-neutrophil cytoplasmic antibody (ANCA) negative associated vasculitis Jorge Vaz Lourenço (Portugal)

Immunological characterization of wilson disease Marcello Albanesi (Italy)

IgG4 related disease and ligneous conjunctivitis in a girl: A coexistence or a relationship? Banu Bozkurt (Turkey)

Hereditary angioedema Sylvia Jacob (Portugal)

Role of immune inflammatory mediators in the pathogenesis of inflammatory and noninflammatory chronic abacterial prostatitis G N Drannik (Ukraine)

LNA probes for detecting donor cell-free DNA in sera of solid organ transplant recipients Georgii Olegovich Gudima (Russia)

Cancer-testicular antigens as a basis for the creation of personalized autologous vaccines for urothelial cancer Tatiana Alexandrovna Slavyanskaya (Russia)

Hereditary alpha-tryptasemia due to a TPSAB1 gene duplication associated with multifocal sclerotic bone disease Shuayb Elkhalifa (United Kingdom)

Features of humoral immunity in adenoma and prostate cancer Sergey Yurievich Tereshchenko (Russia)

Asthma > Precision Medicine

Thematic Poster Sessions (TPS) TPS 02 Asthma: Biomarkers Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 2 in e-Poster Area A (FIL)

Chairs Isabella Annesi-Maesano (France) Apostolos Bossios (Sweden)

Metabolomics reveal serum HETEs levels are correlation with allergic asthma in children: Three years drug and allergen immunotherapy as evidences Peiyan Zheng (China)

Childhood fractional exhaled nitric oxide as a predictor of asthma symptoms in adolescence Hui-Ju Tsai (Taiwan)

Oxidative stress in asthma Barbara Rogala

NGAL (neutrophil gelatinase-associated lipocalin) and IL-5 (interleukin-5) potential biomarkers for asthma-COPD overlap differentiation from asthma and COPD Miroslav Mihaylov (Bulgaria)

Biomarkers of severe eosinophilic asthma: The role of induced sputum eosinophils, FeNO and blood eosinophils Bjarke Hviid Vyff (Denmark)

Sputum cytokine profiling according to different asthma sub-types Malgorzata Proboszcz (Poland)

Periostin and IL-10 in asthma and COPD Ioana Corina Bocsan (Romania)

Clusters in Lithuanian asthma cohort study based on immune markers Edita Gasiuniene (Lithuania)

Biomarkers of eosinophilic airways inflammation in patients with severe asthma: A real life study Galina Sergeeva (Russia)

Clinical characteristics of asthma according to blood eosinophil count Young-Hee Nam (South Korea)

Does fractional exhaled nitric oxide predict non-specific bronchial hyperresponsiveness in childhood asthma? Yeong Ho Rha (South Korea)

Periostin is not associated with clinical assessment of asthma control in allergic asthma Adi Surya Komala (Indonesia)

Assessment of cytogenetic alterations in cells of asthmatic patients Alexander Viktorovich Emelyanov (Russia)

Serum level of eosinophil-derived neurotoxin: A biomarker for asthma severity in adult asthmatics Youngsoo Lee (South Korea)

The potential diagnostic value of periostin in patients with allergic bronchopulmonary aspergillosis Ge Wu (China)

Personalized FeNO monitoring as a predictor of asthma control Ivan Shishimorov (Russia)

Inflammatory markers that binds receptor of advanced glycation end products(RAGE) in patients with asthma and ultrasound right cardiac findings Nikolaos Gkavogiannakis (Greece)

HETEs and prostaglandins distinguish asthma-COPD overlap from COPD by metabolomics study Jian Lin Wu (Hong Kong SAR) Asthma > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 03 Asthma: Diagnosis Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 3 in e-Poster Area A (FIL)

Chairs Sergio Bonini (Italy) Ana Todo-Bom (Portugal)

The impact of GLI on spirometry interpretation in paediatric asthma António Jorge Cabral (Portugal)

Diagnostic performance of the methacholine versus mannitol bronchial challenge tests for diagnosis of bronchial hyperresponsiveness: A systematic review and meta-analysis Yeon Namgung (South Korea)

Does allergen susceptibility and allergen types affect the level of bronchial hyperactivity? Tugçe Yakut (Turkey)

Cut-off value for Exercise induced bronchoconstriction EUNSIL KOH (South Korea)

Over or under-detection? A comparison of exercise and eucapnic voluntary hyperpnoea in the evaluation of exercise-induced bronchoconstriction Oliver J Price (United Kingdom)

Induced sputum eosinophil and exhaled nitric oxide as tools for diagnosis of asthma Jin-Young Lee (South Korea)

Is it clinical features or biomarkers in predicting asthma in wheezy children? Hakan Guvenir (Turkey)

Airway remodeling and small airway disease Catalina Cojanu (Romania)

Serology with specific IgE in children with asthma could lead to substantial cost savings for the NHS: A population-based simulation study Barbara Mascialino (Sweden)

A Novel Asthma Monitoring Device Studying Symptomatic Asthmatics During The First Month Of Corticosteroid Treatment Lee Paul Brooks (United Kingdom)

Clinical efficacy of information and communication technology based monitoring of asthma: A prospective, randomized controlled, multicenter study Hyun Jung Jin (South Korea)

Bioluminescence analysis of saliva as non-invasive evaluation assay of physical exertion in human Sergey Yurievich Tereshchenko (Russia)

Romanian experience behind awareness and screenings campaigns on the world asthma day in the last 4 years Ramona Elena Nedelcu (Romania)

Air pollution, lung function and inflammatory markers in adult asthma based on land use regression, inverse distance weighting and kriging method Tsu-Nai Wang (Taiwan)

Long term follow-up of cough variant asthma Junehyuk Lee (South Korea)

Peak expiratory flow versus spirometry for diagnosis of asthma in adults Diana Andrea Herrera Sánchez (Mexico) Impact of ban of humidifier-disinfectants-sales on preschool asthma in Korea: A nation-wide interrupted time series Hyeon-Jong Yang (United States)

ENT > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 04 Rhinitis and rhinosinusitis management Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 4 in e-Poster Area A (FIL)

Chairs Claire Hopkins (United Kingdom) Peter Valentin Tomazic (Austria)

Allergic rhinitis (AR) therapy decisions during a routine consultation: A multicenter, cross-sectional study (AR therapy survey) Gabriella Gálffy (Hungary)

The efficacy of the fixed combination of mometasone furoate and azelastine hydrochloride as a nasal spray in adult patients with perennial rhinitis Natalia Nenasheva (Russia)

Mometasone furoate plus isotonic nasal saline versus isotonic nasal saline alone in geriatric chronic rhinitis: An open-label, active comparator, randomized trial Jose Laerte Boechat (Brazil)

A multicenter study on the efficacy and safety of So-Cheong-Ryong-Tang for perennial allergic rhinitis Inhwa Choi (South Korea)

Algorithm for allergic rhinitis treatment based on the use of powder hydroxy-propyl-methyl-cellulose sealant Todor A. Popov (Bulgaria)

Effect of yoga training on nasal blood flow and symptoms in allergic rhinitis patients Wannaporn Tongtako (Thailand)

Effect of postoperative xylitol nasal irrigation on patients with sinonasal diseases Soo Whan Kim (South Korea)

Blood eosinophil may predict radiographic sinus opacification in patients with chronic rhinitis WOOHYUN LEE (South Korea)

Endoscopic sinus surgery under navigation system. Analysis report of 40 cases with chronic polypoid rhinosinusitis Doston Mirkomilovich Sultonov (Uzbekistan)

Initial clinical results evaluating the safety and efficacy of olfactory mucosa-derived mesemchymal stem cell therapy as adjunctive treatment for chronic laryngeal and/or tracheal stenosis Lawrence DuBuske (United States)

Treatment of paranasal sinus indolent mucormycosis Yong-Wan Kim (South Korea)

Postoperative improvement of headache in chronic rhinosinusitis BYUNG GUK KIM (South Korea)

The Effect Of Endoscopic Sinus Surgery And/Or Medical Treatment In Patients With Aspirin-Exacerbated Respiratory Disease Daeyeon Kim (South Korea) ENT > Ocular Allergy > Basic Immunology > Basic Allergology

Thematic Poster Sessions (TPS)

TPS 05 Pathophysiology of rhinitis and conjunctivity Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 5 in e-Poster Area A (FIL)

Chairs Jean-Luc Fauquert (France) Ralph Mösges (Germany)

Polymorphism in a tight junction gene CLDN10 confers susceptibility to allergic rhinitis Xu Zhang (China)

Proprotein convertase PACE4 modulates basal progenitor cell fate in IL-4-stimulated human nasal epithelial cells Joo-Heon Yoon (South Korea)

Eosinophil chemokines and clara cell protein 16 production in nasal mucosa of patients with perennial allergic rhinitis Aleksandar Peric (Serbia)

CD48 in intermittent allergic rhinitis Joanna Glück (Poland)

Evaluation of PD-1 expression on different subsets of T-lymphocytes in donors and patients with allergic rhinitis and bronchial asthma Nadezhda Knauer (Russia)

Evaluation of basophil response in dual allergic rhinitis patients Carmen Rondon (Spain)

The effects of myeloid and plasmacytoid dendritic cells on group 2 innate lymphoid cells in allergic rhinitis patients Qing-Ling Fu (China)

Dysregulated coagulation cascade and fibrinolysis system lead to fibrin deposition in allergic rhinitis Seung-No Hong (South Korea)

LncRNA FR215775 regulates Th2 differentiation through Cav1.3 pathway in AR murine chunquan zheng (China)

Involvement of galanin and galanin receptor 2 in a mouse model of allergic rhinitis Hidenori Yokoi (Japan)

IL-9 expression in ocular allergy Mali Eskandarpour (United Kingdom)

IgE ratio in tears: A predictive tool of ocular allergic inflammation Françoise Brignole-Baudouin (France)

Nasal provocation test and evaluation of the predictive instruments for the diagnosis of local allergic rhinitis Albertina Varandas Capelo (Brazil)

Correlation between nasal provocation test, skin reativity and specific IgE to dermatophagoides pteronyssinus and lepidoglyphus destructor Sofia Martins Farinha (Portugal)

Asthma > Precision Medicine Thematic Poster Sessions (TPS)

TPS 06 Genetics, epigenetics and mechanisms Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 7 in e-Poster Area B (FIL)

Chairs Paul Lavender (United Kingdom) Tomás Chivato (Spain)

Homozygous status for CHI3L1 variant is associated with decreased prescribing of inhaled corticosteroids Patricia Soares (Portugal)

GSTT1 and GSTM1 polymorphisms in asthma Margarida Cortez E Castro (Portugal)

Sensitivity towards house dust mite induced nasobronchial allergy in relation to TGF-ß1 C-509T polymorphism among west bengal population, India PRITI MONDAL (India)

Association of asthma and lipoprotein cholesterol levels: A two-sample mendelian randomization analysis Yi-Shian Liu (Taiwan)

A genome-wide association study identify the association between SNP Rs2304053 rs215274 and adult asthmatics with obesity abstract Yu-Hsien Cheng (Taiwan)

Particulate matter and asthma: Effect modification by tumor necrosis factor-a polymorphisms in lung function Albertina Varandas Capelo (Brazil)

Epithelial posttranscriptional gene regulatory networks in chronic airway inflammation: In silico mapping of RNA-binding protein expression Luca Ricciardi (Italy)

Dysregulation of NLRP3 inflammasome pathways in patients with severe asthma Efthymia Theofani (Greece)

The inflammatory effects in response to different exercise intensities: A systematic review Olga Lourenço (Portugal)

Allergen activated eosinophils promote expression of extracellular matrix proteins in airway smooth muscle cells and induce their migration in asthma Ieva Janulaityte (Lithuania)

The effect of SERPINB1 protease inhibitor on the inflammatory response genes in bronchial epithelial cells Dilara Karaguzel (Turkey)

A new approach for understanding the crosstalking signalling bone morphogenetic proteins pathways between different forms of specific and non-specific challenge test Marcelina Kocwin (Poland)

Comparison of the oxidative stress response induced by tert-butyl hydroperoxide in airway resident and inflammatory cells Dilara Karaguzel (Turkey)

The role of ?d T cells in immunopathogenesis of respiratory allergies Nunu Mitskevich (Georgia)

House dust mite-derived HODEs shape the development and progression of allergic airway inflammation Nestor González Roldán (Germany)

The feature of the immune status of the phenotype of bronchial asthma with obesity Ella Vitalievna Churyukina (Russia)

Metabolic activity deviations in patients with hormone-dependent asthma Valeriy Valerievich Smirnov (Russia) Investigation on the immunological effects of regular physical exercise Gábor Papp (Hungary)

Dermatology > Allied health and primary care > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 07 Living with skin disease Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 8 in e-Poster Area B (FIL)

Chairs Charlotte G. Mortz (Denmark) Leonor Rosário Carneiro-Leão (Portugal)

Hereditary angioedema awareness in turkish emergency department physicians and the results of a brief video assisted education Derya Ünal (Turkey)

Persistent angioedema of 1.5 years of evolution Lidia Farrarons Lorente (Spain)

Hereditary angioedema in a real clinical practice Alexander Viktorovich Emelyanov (Russia)

Real World Data Of Canadians Living With Hereditary Angioedema: Part 4- Treatment Satisfaction William H Yang (Canada)

Real world data of canadian’s living with hereditary angioedema: Part 1- demographics Jodi Valois (Canada)

Real world data of canadian’s living with hereditary angioedema: Part 2- attack profile Jodi Valois (Canada)

Co-existence of type 3 hereditary angioedema and polycystic ovary syndrome Ozlem Yilmaz (Turkey)

Impact of the body mass index in patients with mastocytosis Aleksandra Górska (Poland)

Psychoactive drugs use in patients with chronic urticaria or suspected drug hypersensitivity Joana Gouveia (Portugal)

Facial and urticaria due to potassium-sparing diuretic Antonio Moreno-Fernandez (Spain)

Allergy to cloxacillin versus skin disease. A case report María Del Mar Cano-Mollinedo (Spain)

Psychosomatic aspects of allergic diseases in adult population of Kazakhstan Saule Zhumambayeva (Kazakhstan)

Blood marker for differentiating among eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome, and toxocariasis Young Il Koh (South Korea)

Cutaneous mastocytosis: A report of two cases Polina Shahid (Bulgaria)

Asthma > Clinical Allergology Thematic Poster Sessions (TPS)

TPS 08 Asthma: Clinical aspects Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 9 in e-Poster Area B (FIL)

Chairs Mariana Couto (Portugal) Antonio Nieto Garcia (Spain)

Clinical phenotypes of severe asthma with fungal sensitization and treatment with biologics Giuseppe Guida (Italy)

Early and late onset asthma in the elderly Joana Afonso Branco (Portugal)

Seasonal alteration of isolated pathogens in children hospitalized with asthma exacerbation Hiroki Yasudo (Japan)

Factors associated with low influenza and pneumococcal vaccination uptake in patients with severe asthma Mariana Paula Rezelj (Slovenia)

Adult asthma in a district hospital: A retrospective study Catarina Custódio (Portugal)

Asthma may increase the risk of non small cell carcinoma I-Jen Wang Wang (Taiwan)

Risk of in patients with chronic respiratory disease: A nationwide population-based cohort study Chih-Yi Lin (Taiwan)

Evaluation of the risk of developing thromboembolic events in patients with bronchial asthma Norma Susana De Barayazarra (Argentina)

The interaction effect between early cigarette smoke and early-onset asthma on the risk of mental illness Pei-Jing Yang (Taiwan)

Bronchial asthma and scleroderma Plamen Hristov Yakovliev (Bulgaria)

Bronchial asthma and pulmonary tuberculosis as comorbid diseases Sergii Zaikov (Ukraine)

Asthma and obstructive sleep apnea Maria Alvarenga (Portugal)

Respiratory function features in pregnant women suffering from bronchial asthma olga titova (Russia)

Relationship between asthma and sarcopenia in the elderly population: A nationwide cross-sectional study from KNHANES 2008-2011 Hakyeong Won (South Korea)

Respiratory food allergy: A pilot study Mahboubeh Mansouri Kharaghani (Iran)

Allergic bronchopulmonary aspergillosis as a complication of COPD: A new entity Colas Tcherakian (France)

Association between asthma control level and degree of anxiety in adult patients Diana Andrea Herrera Sánchez (Mexico)

Bronchiectasis in severe asthma, a distinct clinical profile Stephanie van Loon-Kooij (The Netherlands)

Two cases of adult asthma patients suffered from repeated pneumonia due to inhaled corticosteroid Tomohiro Matsunaga (Japan)

Persistent rhinitis and asthma due to ferret`s allergy LETICIA URIARTE VEGA (Spain)

Montelukast - an unknown cause of acute fibrinous organizing pneumonia (AFOP) Inês Sucena Pereira (Portugal)

Allied health and primary care > Allergy diagnosis and systems medicine > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 09 The wider world: Novel diagnostics and quality care Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 10 in e-Poster Area B (FIL)

Chairs Eva Untersmayr (Austria) Luis Miguel Borrego (Portugal)

Two-site immunoassays for the quantification of major egg allergens ovomucoid (Gal D 1) and ovalbumin (Gal D 2) Max Bermingham (United Kingdom)

Do hypoallergenic horses exist? Comparison of Equ C 4 levels in dander from ten horse breeds Susanne Victor (Sweden)

Adherence to the STROBE checklist in articles published in EAACI journals: A systematic review Elena Wiehn (Germany)

Study of cases of hypersensitivity to low molecular weight heparins in an allergy unit Lucía González Bravo (Spain)

Infection risk assessment of epinephrine auto-injectors in vitro Jacqueline Alig (Germany)

Epinephrine auto-injector administration results in consistent delivery across subjects with different skin-to-muscle distances Russ No Rackley (United States)

Perceived immune functioning before and after switching to raw milk consumption: A retrospective survey among us adults Joris Cornelis Verster (The Netherlands)

A case of eosinophilic hyperplastic lymphogranuloma on arm and eye orbit Akiko Yamaide (Japan)

The co-existence and diagnosis of allergic & gastrointestinal symptoms in the adults with food allergy Kaye Wheeler (United Kingdom)

Significant hypereosinophilia accompanying an uncommon reason: Giardiasis Emine Vezir (Turkey)

Chemiluminescence activity of neutrophil granulocytes and monocytes in blood in children with helicobacter pylori-associated erosive ulcer lesion of stomach and duodenum Sergey Yurievich Tereshchenko (Russia)

Primary Sjogren’s syndrome in serbian patients: Evaluation of health–related quality of life and fatigue Rada Miskovic (Serbia)

The Immune Status Questionnaire (ISQ): Further Validation In A Dutch And International Sample Stephanie Balikji (The Netherlands)

The positive effects of having a holiday on immune fitness, psychological health, and mood Lizanne Arnoldy (The Netherlands)

Exposome pressure on immune fitness: A layman’s perspective Joris Cornelis Verster (The Netherlands)

Acute alcohol effects on cytokine concentrations in healthy young adults Aurora J Van De Loo (The Netherlands)

Asthma > Biologicals > Precision Medicine

Thematic Poster Sessions (TPS)

TPS 10 Biologicals and therapeutic approaches in Asthma Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 11 in e-Poster Area B (FIL)

Chairs Matteo Bonini (Italy) Brecht Steelant (Belgium)

Real life data on treatment response to mepolizumab in patients with severe eosinophilic asthma Maria Ntakoula (Greece)

Mepolizumab for the treatment of severe eosinophilic asthma: A real-life study of 27 patients Lucia Masciopinto (Italy)

Evaluation of patients with severe asthma with 6 months of treatment with mepolizumab - The experience of the pulmonology services of 2 tertiary referral hospitals Inês Sucena Pereira (Portugal)

Mepolizumab: Monocentric one-year experience Maria Francesca Spina (Italy)

Treatment of severe asthma with mepolizumab: The influence of obesity Ana Luísa Fernandes (Portugal)

Personalized approach to omalizumab asthma treatment - the phenotype concept. A single reference center experience Daria Fomina (Russia)

Can peripheral eosinophilia in aspirin-induced airway disease (AERD) increasing tendency after aspirin desensitization therapy? selver seda mersin (Turkey)

Omalizumab in real life: A retrospective study investigating clinical and airway inflammatory outcomes AN Frix (Belgium)

Omalizumab in the treatment of eosinophilic granulomatosis with polyangiitis (EGPA): Single-center experience in 18 cases Sevim Bavbek (Turkey)

Beta2 agonists and doping: The potencial to improve physical performace in athletes Olga Lourenço (Portugal)

Asthma-related outcomes in a real-world study of MP-AzeFlu to treat allergic rhinitis Ludger Klimek (Germany)

Asthma and severe obesity: Glucocorticoid sensitivity before and after bariatric surgery Marina Bantulà Fonts (Spain)

Bacterial lystes as add-on therapy in obstructive lung diseases: A systematic review and a meta-analysis Geertje Maria de Boer (The Netherlands)

Exercise and physical activity impact on the allostatic load: Evidence from a two steps clinical trial Diana Margarida Silva (Portugal)

Clinical characteristics of patients with AERD and eligibility for therapy with monoclonal antibody in a Brasilian cohort Gabriella Melo Fontes Silva Dias (Brazil)

Overlap of the indication of biological therapy in severe asthma according to the prescription data sheets Inmaculada Ibarra Calabuig (Spain)

Asthma > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 11 Asthma: Management Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 13 in e-Poster Area C (FIL)

Chairs Bulent Sekerel (Turkey) Jasper Kappen (The Netherlands)

Compliance with home nebulizer therapy and asthma control level in a cohort of asthmatic children: First survey in China Deyu Zhao (China)

Efficacy of mepolizumab in severe eosinophilic asthma by baseline eosinophil count and exacerbation history: Meta-analysis of two phase 3 trials Namhee Kwon (United Kingdom)

Adverse events of high dose of inhaled corticosteroid for patients with severe asthma João Paulo de Assis (Brazil)

?ssessment of the functional status and application of long-acting m-anticholinergic in children with bronchial asthma in real clinical practice Ella Vitalievna Churyukina (Russia)

Efficacy of omalizumab after 16 weeks treatment in a severe cortico dependent eosinophilic non-allergic asthma Enkeleda Kryeziu Zekthi (Albania)

Allergic bronchopulmonary aspergillosis (ABPA) and omalizumab treatment Pilar Mur Gimeno (Spain)

Patient-physician discordance in the assessment of adherence to inhaled medication Cristina Jácome (Portugal)

Evaluation of the asthmatic children's quality of life Marzieh Tavakol (Iran)

Asthma control in real clinical practice Galina Sergeeva (Russia)

Severe asthma questionnaire: Translation to portuguese and cross-cultural adaptation for use in Portugal Bárbara Kong Cardoso (Portugal)

Lithuanian patient’s opinion: Allergy diary MASK is user friendly Violeta Kvedariene (Lithuania)

Asthma control test reflects not only lung function but also airway inflammation in stable asthma of children Hye Yeon Choi (South Korea)

National program of asthma management in the Republic of Kazakhstan Zhannat Ispayeva (Kazakhstan) Patients education and adherence to treatment in management of bronchial asthma Kostiantyn Dmytriiev (Ukraine)

Tidal changes in respiratory reactance are sensitive indicators of airway obstruction in severe asthma JOSEANE CHIABAI (Brazil)

Comparison of responses to nasal and whole lung allergen challenges in mild allergic asthmatic subjects with allergic rhinitis Yanqing Xie (Canada)

Exercise-induced bronchospasm in children: Which test to choose? Irena Ivkovic-Jurekovic (Croatia)

Clinical Immunology > Basic Immunology

Thematic Poster Sessions (TPS)

TPS 12 Cellular mechanisms of autoimmunity Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 14 in e-Poster Area C (FIL)

Chairs Florentina Sava (United Kingdom) Marc Veldhoen (Portugal)

Inaugural hereditary angioedema in a child Marisa Paulino (Portugal)

Autoinflammatory syndrome with recurrent neutrophil-rich urticarial exanthema, excessively increased inflammatory markers and response to anakinra in a 77 year-old male patient Andreas Recke (Germany)

Minor leukocyte subsets in patients with stage Ii pancreatic cancer Andrei Hancharou (Belarus)

The role of cytokine regulation in the progression of obstructive jaundice of malignant origin Sergey Yurievich Tereshchenko (Russia)

Features of the functional activity of neutrophils in obstructive jaundice of cholelithiasis Sergey Yurievich Tereshchenko (Russia)

Peculiarities of TLR9 expression on immunocompetent cells in patients with the reactive arthritis induced by the epstein-barr viral infection and the rheumatoid arthritis Marta Lomikovska (Ukraine)

Refractory leukocytoclastic vasculitis – case report Dana Chesa (Romania)

Functional characteristics of B2 lymphocytes with varying degrees of activity of the seropositive variant of the course of articular rheumatoid arthritis Lyudmila P Sizyakina (Russia)

Vitamin D deficiency and treg cell insufficiency in patients with secondary systemic vasculitis Lawrence DuBuske (United States)

PFAPA syndrome in Slovakia Lenka Kapustová (Slovakia)

Neutrophilic urticarial dermatosis (NUD) comorbidity of / a manifestation of drug-induced lupus? Adriana Maria Stefan (Romania)

Etiology and prevalence of stevens-johnson syndrome in Ukraine Oleksandr Katilov (Ukraine) Immunological parameters in psoriasis and psoriatic arthritis patients in Eastern Siberia of Russia Sergey Yurievich Tereshchenko (Russia)

An unexpected malignancy in children with ataxia telangiectasis: Intracerebellar hemangiopericytoma Ilknur Kulhas Celik (Turkey)

Interleukin-21 receptor (IL-21R) deficiency in a patient with difficult asthmatic and multiple food allergy and CVID-like conditions following early childhood Ilknur Kulhas Celik (Turkey)

Food allergy > Allergy diagnosis and systems medicine > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 13 Diagnosis of food allergy Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 15 in e-Poster Area C (FIL)

Chairs Luis Taborda-Barata (Portugal) Ronald van Ree (The Netherlands)

Clinical value of basophile activation test in cashewnut allergy Petteri Röntynen (Finland)

Differential IgE binding to freshwater and seawater fishes in a chinese population of fish allergic subjects Nicki Yh Leung (Hong Kong SAR)

Molecular diagnosis could rule out hipersensitivity in patients with suggestive history of shrimp allergy Carlos Serrano (Colombia)

Self-reported food allergic symptom and results of IgE sensitization in children Jeongmin Lee (South Korea)

Tolerance to baked milk in children with cow’s milk allergy Burçin Beken (Turkey)

Severity of the presentation of LTP allergy in patients with respiratory symptoms María Ruano-Zaragoza (Spain)

Optimization and merging of food product data and food composition databases for medical use Alexander Münzberg (Germany)

Sesame allergy – to challenge or not to challenge that is the question diti machnes maayan (Israel)

Seeking oleosins Joan Doménech Witek (Spain)

Peanut flour protein with defined allergen content for use as reference standard Sabina Wünschmann (United States)

Peamaclein (Pru P 7): Recombinant expression, physicochemical characterization and its application for component resolved diagnosis Christoph Nagl (Austria)

Investigation of purity of ovomucoid-specific IgE test kit with mouse-human chimeric IgE antibody Hironobu Fukuda (Japan)

Component-resolved diagnostics can contribute reducing the burden of food allergy among swedish schoolchildren: A population-based simulation study Barbara Mascialino (Sweden)

Estimation of the clinical significance of IgG analyses in atopic and non-atopic patients with food dependent symptoms Dorota Myszkowska (Poland)

Citrus seed allergy and cross-reactivity Oyindamola Stephanie Kayode (United Kingdom)

Recombinant Ses i 1 - a useful diagnostic marker in sesame allergy Marie Holmqvist (Sweden)

Ana O 3 is a reliable marker for cashew nut allergy in adults Anna Maria Ehlers (The Netherlands)

Dermatology > Pediatrics > Clinical Immunology > Biologicals

Thematic Poster Sessions (TPS)

TPS 14 Urticaria and angioedema I Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 16 in e-Poster Area C (FIL)

Chairs Tabi Leslie (United Kingdom) Maria Elisa Pedro Fernandes (Portugal)

IgE anti-TPO as a biomarker of different clinical phenotypes in chronic spontaneous urticaria Jorge Sánchez (Colombia)

Systemic and local evidence for complement involvement in chronic spontaneous urticaria Mehran Alizadeh Aghdam (The Netherlands)

Efficacy and safety of omalizumab in patients with chronic inducible urticaria VASILIKI VOUKELATOU (Greece)

Chronic urticaria – what about montelukast? Míriam Araújo (Portugal)

Effectiveness in treatment of solar urticaria with omalizumab: A case report SARA ANAYA (Spain)

Concentration of vitamin D receptors (VDR) of mononuclear blood cells and level of total IgE in patients with chronic spontaneous urticaria Raisa Yakovlevna Meshkova (Russia)

Dupilumab as a novel therapy for difficult to treat chronic spontaneous urticaria Rachel S. Simpson (Canada)

The management of acute urticaria, a systematic review Fariza Badloe (The Netherlands)

Questionnaire to evaluate the first-generation antihistamine side effects in patients with chronic spontaneous urticaria Henrikki Gomes Antila (Brazil)

Treatment of cold urticaria with omalizumab at the Hospital Universitario de Guadalajara (Spain) Remedios Cárdenas Contreras (Spain)

Efficacy of omalizumab in a patient with chronic spontaneous urticaria and several subtypes of inducible urticaria Elizaveta Gribaleva (Russia)

Evaluation of clinical characteristics and autoreactivity in CSU patients by ASST and BAT João Marcelino (Portugal)

Omalizumab versus cyclosporin-A for the treatment of chronic spontaneous urticaria: Are there specific patient characteristics or biomarkers to indicate response to treatment? Emek Kocatürk (Turkey)

How to manage omalizumab in a relapse of chronic spontaneous urticaria? Caroline Brigido Paredes (Spain)

Two autoimmune diseases in addition to chronic spontaneous urticaria in an adolescent Emilia Schmid (Germany)

A case of cold induced anaphylaxis Emine Vezir (Turkey)

Cold urticaria and human parvovirus B19 infection? – A case-report Rita Brás (Portugal)

Melkersson-rosenthal syndrome presenting as a misdiagnosis of angioedema Ruta Kavaliauskaite (Lithuania)

Food allergy > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 15 Case reports in food allergy I Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 17 in e-Poster Area C (FIL)

Chairs Mario Morais-Almeida (Portugal) Sonsoles Infante (Spain)

A case with acute baked milk protein-induced enterocolitis syndrome Ozlem Yilmaz (Turkey)

Two Cases Of Allergy To Lupin In Vegan Ice-Cream Samia Azmi (United Kingdom)

Anaphylaxis due to allergy to coconut Heleia González Cuervo (Spain)

Case report: Goat’s milk anaphylaxis in a cow’s milk tolerant child Si Hui Goh (Singapore)

MOLD - triggered anaphylaxis Beatriz Torres Pérez (Spain)

Cow's milk allergy - a hidden diagnosis of late presentation Maria Inês Silva (Portugal)

A case of eosinophilic gastroenteritis caused by milk allergy in neonate with sepsis Myongsoon Sung (South Korea)

Cat-Pork syndrome as cause of anaphilactic reaction to well cooked meat Inês Sangalho (Portugal)

Two adult cases of jellyfish food allergy Tomoyuki Kimura (Japan)

Anaphylactic shock to anemones (actinia equine) intake Alba García-Moral (Spain)

Clinical case of urticaria, accompanied by multiple cross sensitization to pan-allergen tropomyosin, confirmed with multiplex allergy test ALEX Olena Victorovna Sharikadze (Ukraine) First characterization of allergens causative of occupational asthma by lathyrus sativus flour Blanca Barroso García (Spain)

Anaphylaxis induced by baker’s yeast allergy – a case report Iolanda Alen Coutinho (Portugal)

Oral allergy syndrome - a case report Catarina Pereira Coutinho (Portugal)

Scarlet shrimp: Several allergens identified Diana Betancor (Spain)

A case of allergic caused by fish, crustacea, and mollusca Daisuke Shigeta (Japan)

A first case of LTP syndrome in Japan Rai Fujimoto (Japan)

Quinoa allergy: A hidden allergen Shuayb Elkhalifa (United Kingdom)

Allergy to – two unusual cases Dagmar Jamiolkowski (Switzerland)

Clinical Immunology > Clinical Allergology > Dermatology > Pediatrics

Thematic Poster Sessions (TPS)

TPS 16 Trends in contact dermatitis Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 19 in e-Poster Area D (FIL)

Chairs Vera Mahler (Germany) Susan Chan (United Kingdom)

Metal allergy related to the use of orthopaedic prosthesis after trauma and normal aging process vincenzo mancuso (Italy)

Is atopy a predisposing factor for contact hypersensitivity – results from patch testing unit of 200 consecutive patients Martina Yaneva (Bulgaria)

The morph of an irritant contact dermatitis into an allergic dermatitis Ana-Maria Moiceanu-Sovarel (Romania)

Airborne contact dermatitis and hand eczema caused by 2-Hydroxyethylmethacrylate (2-Hema)-case report of occupational contact allergy Denislava Nedeva (Bulgaria)

Short exposures and glove protection from (meth)acrylates in nail beauticians – thoughts on a rising concern Francisca Jácome Morgado (Portugal)

Occupational contact dermatitis in three adolescent males in the differential diagnosis of raynaud phenomenon Emine Vezir (Turkey)

Protein contact dermatitis in combination with chronic spontaneous urticaria and atopic dermatitis: A case report Elena Petkova (Bulgaria)

Contact urticaria in a baker after a long term wheat flour exposure - a case report Plamena Ivanova Novakova (Bulgaria) Non-invasive diagnosis of contact dermatitis by in vivo imaging Marine-Alexia LEFEVRE (France)

Isobornyl acrylate- contact allergen in continuous glucose sensor system Nicola Wagner (Germany)

Anti-inflammatory activity of humic acids in murine model of allergic contact dermatitis Yury Vladimirovich Zhernov (Russia)

Food allergy > Clinical Allergology > Pediatrics

Thematic Poster Sessions (TPS)

TPS 17 Epidemiology of food allergy I Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 20 in e-Poster Area D (FIL)

Chairs Giovanni Battista Pajno (Italy) Zeynep Ulker Tamay (Turkey)

Substantial variation in food allergy prevalence and causative foods in adults across Europe Sarah A Lyons (The Netherlands)

Characteristics of food allergy in children: National multicenter study Aysen Bingol (Turkey)

Clinical features of 4458 food allergic children from 5 year’s registry Kiyotake Ogura (Japan)

Profilin sensitization – a review of 5 years follow up in an allergy department Inês Sangalho (Portugal)

LTP’s sensitization – a 5 year follow up study Inês Sangalho (Portugal)

LTP and profilin co-sensitization: A 5 years follow-up Inês Sangalho (Portugal)

Sensitization profile and severity of reactions of patients with LTP syndrome from two mediterranean areas with different pollen profile Francisca Gomez Pérez (Spain)

Oral food challenges to nuts in children with LTP sensitization Alexandra Kothra (Greece)

Co-sensitization patterns in children with tree nut and peanut allergy Maria Pasioti (Greece)

Surveillance of pollen-food allergy syndrome in elementary and junior high school children in northwest area of Saitama prefecture, Japan Shunichi Ogawa (Japan)

Determining health preferences of patients and families with food allergies Élise Dufresne (Canada)

Adolescents with a history of food allergy consume less milk, but not other calcium-rich foods, than their non-food allergic peers Jennifer L P Protudjer (Sweden)

Sensitisation and sero-reversion to tick bite induced galactose-1,3-alpha-galactose, meat and dairy sensitisation in New South Wales, Australia Karl William Baumgart (Australia) Is there a relation between legume protein consumption and the prevalence of legume sensitization? Thuy-My Le (The Netherlands)

Lupine allergy in the chilean population: A cross-reactivity study with peanut allergy Traudy Wandersleben (Chile)

Study of the association between food allergic children and vitamin D levels Maria Kostara (Greece)

Prevalence of cofactor enhanced food allergy in the mediterranean area Maria José Castillo (Spain)

Epidemiology of food allergy in Czech Republic, final results of dafall registry Simona no Belohlávková (Czech Republic)

Clinical case of familial Olga I. Sidorovich (Russia)

Potential allergic reaction in patients with food allergy taking complementary and alternative medicine (CAM) containing food ingredients H.C. George Wong (Canada)

Clinical Immunology > Basic Immunology

Thematic Poster Sessions (TPS)

TPS 18 Update on immunodeficiency Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 21 in e-Poster Area D (FIL)

Chairs Isabella Quinti (Italy) Anna Sediva (Czech Republic)

New ellagitannins from geranium sanguineum and punica granatum: Anti-HIV activity and immunosuppressive effect on dendritic cells Yury Vladimirovich Zhernov (Russia)

Secondary immune deficiency syndrome in combatants Lyudmila P Sizyakina (Russia)

A case of severe combined immunodeficiency misdiagnosed as cystic fibrosis Emine Vezir (Turkey)

Hyper IgE syndrome due To DOCK-8 mutation Emine Vezir (Turkey)

Common variable immune deficiency and allergic disorders: Incidence rate, clinical characteristics and diagnosis Limor Rubin (Israel)

Laboratory markers of allergic diseases among patients with common variable immunodeficiency (CVID) Jan Baroš (Czech Republic)

Consequences of non compliance in patient with common variable immunodeficiency disorder (CVID) Jana Vydlakova (Czech Republic)

Phenotypic differences between selective IgA deficiency and other primary immunodeficiencies Yasmina Piloto Orraca (Cuba)

Chediak–higashi syndrome: Lessons from a single-centre case series Alexandra Rodrigues (Portugal) Positive clinical and immunological effects of combine interferon- and immunomodulatory therapy in patients with atypical chronic viral-bacterial co-infections Irina Vadimovna Nesterova (Russia)

Normal NFKB2 gene by sanger sequencing in a patient with hypogammaglobulinaemia, alopecia and central adrenal insufficiency Susan Tadros (United Kingdom)

Humoral and cellular immune decline in a patient with CDC42 deficiency Paria Kashani (Canada)

Basic Allergology > Clinical Allergology > Precision Medicine > Clinical Immunology

Thematic Poster Sessions (TPS)

TPS 19 Insect venom allergy: Clinical aspects Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 22 in e-Poster Area D (FIL)

Chairs Gunter Sturm (Austria) Lisa Arzt-Gradwohl (Austria)

Can low total IgE levels be a risk factor for severe anaphylaxis in venom hypersensitive adult patients? Osman Ozan Yegit (Turkey)

Could the development of systemic reactions during venom immunotherapy be predicted? Adile Berna Dursun (Turkey)

Sensitization to Api M 1, Api M 2, and Api M 4 in Japanese beekeepers who had experienced systemic reactions to honeybee stings Masamitsu Tatewaki (Japan)

Diagnosis of hymenoptera venom allergy in Russia Natalia Vyacheslavovna Kobizskaya (Russia)

Is the clinical manifestation of anaphylaxis in children influenced by the trigger of reaction? Ewa Cichocka-Jarosz (Poland)

Intervention in anaphylaxis in children cohort - one center experience Ewa Cichocka-Jarosz (Poland)

Evaluation of venom allergy, anaphylaxis and adrenaline auto-injector knowledge level in turkish beekeepers and their family members Zeynep Hizli Demirkale (Turkey)

Investigation of the proper use and re-prescription of adrenaline auto-injectors in Japanese beekeepers after a honeybee sting Hirokuni Hirata (Japan)

A case of severe anaphylaxis after wasp sting which revealed systemic mastocytosis with B-chronic lymphocytic leukemia Nikolaos Gkavogiannakis (Greece)

Inaugural and fatal anaphylaxis to wasp venom Catharina Chatain (France)

Omalizumab as a premedication in venom immunotherapy: When is it indicated in systemic mastocytosis? Osman Ozan Yegit (Turkey)

Hymenoptera venom immunotherapy administration through a subcutaneous infusion pump: A safe and effective way to deliver immunotherapy in Chile Lorena Jiusan Linzmayer (Chile) Field re-stings in patients receiving hymenoptera venom immunotherapy Betül Ayse Sin (Turkey)

Presence of diabetes mellitus and history of drug allergy can increase the risk of ineffectiveness of venom immunotherapy Osman Ozan Yegit (Turkey)

Efficacy and safety of venom immunotherapy in a patient with mastocyte activation syndrome – case report Anna Bobcáková (Slovakia)

Care of hymenoptera venom allergy: 12 years experience of a specialized department of algiers Rachid Abdellaziz (Algeria)

The role of component resolved diagnosis in hymenoptera venom allergy AYSE ENGIN (Turkey)

Comparision of allergen sensitization profile in patients with honeybee venom allergy with immunoCAP and immunoblotting Arantza Vega Castro (Spain)

Determination of the presence of component-resolved diagnosis and other relevant allergens in honeybee venom through mass spectrometry Martínez-Gomariz Montserrat (Spain)

The role melecular diagnostic in hymenoptera venom allergic Serbian patients Dragana Jovanovic (Serbia)

Dermatology > Drug allergy > Basic Immunology > Basic Allergology

Thematic Poster Sessions (TPS)

TPS 20 Anaphylaxis, mastocytosis and cutaneous allergic reactions Sunday, 2 June 2019

12:00-13:30 hrs Room e-Poster station 23 in e-Poster Area D (FIL)

Chairs Marcelo Vivolo Aun (Brazil) Hanneke Oude Elberink (The Netherlands)

Post-mortem tryptase cut-off points of main causes of fatal anaphylaxis Lucía González Bravo (Spain)

Ultrasonography for diagnosing acute laryngeal edema in outpatient setting Nicolae Ovidiu Berghi (Romania)

Non food related exercise induced anaphylaxis in a 11 years old male Enkeleda Kryeziu Zekthi (Albania)

Pathologic characteristics of fatal anaphylaxis: A Spanish nationwide 17- year series Jimena Laiseca Garcia (Spain)

Severe and refracter anaphylaxis due to rupture of hydatid liver cyst Emine Vezir (Turkey)

Case report: Human seminal plasma allergy (HSPA) and dog epithelium allergy in Brazil Marcela Pimenta (Brazil)

Conut score as a tool for early detection of poor nutritional status in advances forms of SM Marta Gruchala-Niedoszytko (Poland)

Do pharmacists know how to use adrenaline autoinjectors? Ricardo Moço Coutinho (Portugal)

Histopathological criteria for mastocytosis in the skin Julia Katharina Winkler (Germany)

Impact of allergic disorders and anaphylaxis in mastocytosis, based on the ECNM database Marta Gruchala-Niedoszytko (Poland)

Clinical Village

Clinical Village Sunday, 2 June 2019

12:00-16:00 hrs Room Altice Arena

Company Sponsored Symposia (CSS)

CSS 2 Sunday, 2 June 2019

12:05-13:25 hrs Room Hall 8 (FIL Meeting Centre)

Business Meetings (BM)

BM 1 Working Group Comparative and Veterinary Allergology - Open to all attendees Sunday, 2 June 2019

12:10-13:20 hrs Room Hall 3 (Altice Arena)

Introductory Lecture: Targeting IL-31 in canine atopic dermatitis by active immunization Ana Rostaher (Slovenia)

Business Meetings (BM)

BM 2 Working Group Genomics and Proteomics - Open to all attendees Sunday, 2 June 2019

12:10-13:20 hrs Room Hall 4 (Altice Arena)

Business Meetings (BM)

BM 3 Working Group Infections - Open to all attendees Sunday, 2 June 2019

12:10-13:20 hrs Room Hall 10 (FIL)

Introductory Lecture: The role of viruses in asthma Nikolaos Papadopoulos (Greece)

Business Meetings (BM)

BM 4 Pediatrics Section - Open to all attendees Sunday, 2 June 2019

12:10-13:20 hrs Room Hall 13 (FIL)

Introductory lecture: How can we select patients who may benefit from selective nut eating?" Helen A Brough (United Kingdom)

Report activities Ped Board Montserrat Alvaro Lozano (Spain)

CvP activity Philippe Eigenmann (Switzerland)

PAI Doris Kollmann

Report ETC-PA José Lopes do Santos

Presentation new Board Montserrat Alvaro Lozano (Spain)

Clinical Allergology > ENT > Environmental and occupational allergy > Precision Medicine

Pro & Con Sessions (P & C)

P & C 1 Pollen season may be predicted by aerobiology data modeling Sunday, 2 June 2019

12:15-12:45 hrs Room Pro & Con Arena (FIL)

Chair Jeroen Titus Buters (Germany)

Pro Mikhail Sofiev (Finland)

Con Maximilian Bastl (Austria)

Company Sponsored Mini Symposia (CSMS)

CSMS 1 Sunday, 2 June 2019

12:30-13:00 hrs Room Hall 11 (FIL) Company Sponsored Mini Symposia (CSMS)

CSMS 2 Sunday, 2 June 2019

12:30-13:00 hrs Room Hall 12 (FIL)

Dermatology > Biologicals > Clinical Allergology > Clinical Immunology

Pro & Con Sessions (P & C)

P & C 2 Omalizumab should be prescribed in patients with chronic spontaneous urticaria when antihistamine fails Sunday, 2 June 2019

12:45-13:15 hrs Room Pro & Con Arena (FIL)

Chair Peter Schmid-Grendelmeier (Switzerland)

Pro Marcus Maurer (Germany)

Con Clive Grattan (United Kingdom)

Company Sponsored Symposia (CSS)

CSS 3 Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 5 (Altice Arena)

Pediatrics > Dermatology

Hot Topic Sessions (HT)

HT 2 Skin care interventions for the primary prevention of atopic dermatitis Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 10 (FIL)

Chairs Yukihiro Ohya (Japan) Karin Lødrup Carlsen (Norway)

Skin intervention studies and allergy prevention Helen A Brough (United Kingdom) Results of the PreventADALL trial Håvard Ove Skjerven (Norway)

Results of the BEEP trial Robert Boyle (United Kingdom)

Allergy diagnosis and systems medicine > Clinical Allergology > Food allergy > Basic Allergology

Interactive Symposia (ISYM)

ISYM 1 Enhancing the diagnostic value of basophil activation test in food allergy Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 7 (Altice Arena)

Chairs Edward Frank Knol (The Netherlands) Hans Jürgen Hoffmann (Denmark)

Integrating basophil activation test and component resolved diagnosis in food allergy Peter Korošec (Slovenia)

Integrating basophil activation and mast cell activation tests Alexandra F. Santos (United Kingdom)

Ensuring the reliability and reproducibility of basophil activation test results: An EAACI task force update Hans Jürgen Hoffmann (Denmark)

Allied health and primary care > Dermatology > Pediatrics

Interactive Workshops (IWS)

IWS 2 Managing the diet and skin in eczematous infant Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 6 (Altice Arena)

Chairs Antonella Muraro (Italy) Mario Morais-Almeida (Portugal)

Dietary diversity and timing of complimentary feeding Berber Vlieg-Boerstra (The Netherlands)

Skinnies, creams and ointments Chrissie Wilkes-Holmes (United Kingdom)

Pediatrics > Clinical Allergology > Dermatology > Asthma

Late Breaking Poster Discussion Sessions (LB PDS)

LB PDS 02 Advances in pediatric allergy Sunday, 2 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Joana Gomes Belo (Portugal) Susanne Gabriele Lau (Germany)

?hange in overall concentration of peroxides in case of atopic dermatitis in children Elena Slusareva (Russia)

Unique subpopulations of cord blood innate lymphoid cells are associated with lung function at 6 weeks of age in babies born to mothers with asthma during pregnancy Gabriela Martins Costa Gomes

Which angioedema is hereditary angioedema in childhood? Melike Kahveci (Turkey)

Perinatal factors and risk of atopy in preschool children Ana Rita Presa (Portugal)

Outcomes in eosinophilic oesophagitis for paediatric patients in Northern England Ben Shillitoe (United Kingdom)

Single dose beta-lactam oral challenge in a low risk paediatric cohort: Parental satisfaction and possibility of replicating in primary care Hilary I Allen (Ireland)

Descriptive study of allergic diseases in children vs adults consulting at the emergency health care, infanta leonor- University Hospital, Madrid-Spain Ana Prieto-Moreno Pfeifer (Spain)

Definition of the clinical phenotype of severe Atopic Dermatitis with Allergic Gastrointestinal Inflammatory Origins - the ADAGIO Complex Emma Ladlow (United Kingdom)

The pine-tar study: Effect of pine-tar bath on disease severity in moderate-to-severe childhood eczema – A 3 month, randomized, crossover, investigator-blinded clinical trial Jeng Sum Charmaine Kung (Hong Kong SAR)

High percentage of uncontrolled asthma in children referred for atopic diseases other than asthma Hannah M Kansen (The Netherlands)

Management of severe allergic reactions in childhood: A single-center study Carmen Olaru (Romania)

A retrospective review of the Nutritional Status of children presenting with ADAGIO complex to the dietetic department of the Great North Children's Hospital Louise J Michaelis (United Kingdom)

Paediatric eosinophilic allergic diseases: Clinical phenotype and related parental quality of life - the BREAD study Louise J Michaelis (United Kingdom)

Ocular Allergy > Basic Immunology > Biologicals

Oral Abstract Sessions (OAS)

OAS 05 Mechanisms and management of severe ocular allergy, whats new? Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 11 (FIL)

Chairs Banu Bozkurt (Turkey) Virginia Lysbeth Calder (United Kingdom)

Session roadmap Virginia Lysbeth Calder (United Kingdom)

Conjunctival transcriptome analysis reveals the overexpression of multiple microbes-associated molecular patterns (MAMPs) receptors in vernal keratoconjunctivitis Andrea Leonardi (Italy)

Autophagy in vernal keratoconjunctivitis and the role of TNF-alpha Rocco Luigi Modugno (Italy)

Long term efficacy of omalizumab in severe ocular allergy in children Serge Doan (France)

Quality of life of patients affected by vernal keratoconjunctivitis: Effect of omalizumab Jean-Luc Fauquert (France)

Triamcinolone acetonide aqueous (TAA) nasal spray improves ocular symptoms of seasonal allergic rhinitis sufferers (SAR): A meta-analysis Leonard Bielory (United States)

Efficacy of N-Acetyl Aspartyl Glutamic versus Fluorometholone 0.1 eye drops in subjects with moderate allergic conjunctivitis to birch pollen challenged in an environmental exposure chamber ALINA Gherasim (France)

Dermatology > Clinical Immunology > Basic Immunology > Biologicals

Oral Abstract Sessions (OAS)

OAS 06 Novel treatments and epidemiology of urticaria and angioedema Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 12 (FIL)

Chairs Tabi Leslie (United Kingdom) Timothy Craig (United States)

Session roadmap Tabi Leslie (United Kingdom)

Ligelizumab retreatment is highly effective in patients with chronic spontaneous urticaria Marcus Maurer (Germany)

Ligelizumab is well tolerated and exhibits a safety profile similar to omalizumab and placebo in patients with chronic spontaneous urticaria Gordon Sussman (Canada)

Clinical efficacy of interleukin-5 receptor alpha blocker benralizumab in the treatment of chronic idiopathic urticaria Jonathan A Bernstein (United States)

Ligelizumab achieves sustained control of chronic spontaneous urticaria symptoms of hives, itch and angioedema: 1-year treatment results Jonathan A Bernstein (United States)

Anaphylaxis in patients with cold urticaria: Data from a mediterranean country Maria Pasali (Greece)

Eczema and urticaria in the adult population in Portugal: A prevalence study Daniela Fernandes Carvalho (Portugal) Asthma > Biologicals > Precision Medicine

Oral Abstract Sessions (OAS)

OAS 07 Tailored asthma treatment Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 13 (FIL)

Chairs Santiago Quirce (Spain) Hae-Sim Park (South Korea)

Session roadmap Santiago Quirce (Spain)

Ketorolac nasal challenge and aspirin treatment in patients with aspirin exacerbated respiratory disease Teresa De Aramburu Mera (Spain)

Young patients with asthma can generate sufficient inspiratory flows via an easy-to-use dry powder inhaler (DPI) delivering salmeterol/fluticasone propionate and budesonide/formoterol treatments Tari Haahtela (Finland)

Dupilumab effect on asthma control and health-related quality of life in patients with oral corticosteroid-dependent severe asthma with comorbid chronic rhinosinusitis with and without nasal polyps Mario Castro (United States)

Increasing aeroallergen sensitization predicts response to omalizumab therapy during the fall season among children with persistent asthma William J Sheehan (United States)

Prevalence of fungal-sensitization and response to mepolizumab in patients with severe eosinophilic asthma Namhee Kwon (United Kingdom)

Change In Post-Bronchodilator FEV1 For Patients With Severe Asthma With Eosinophilic Features Following Benralizumab Therapy Sameer K Mathur (United States)

Food allergy > Basic Allergology > Clinical Immunology

Poster Discussion Sessions (PDS)

PDS 04 Diagnosis and treatment of food allergy Sunday, 2 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Erika Jensen-Jarolim (Austria) Zeynep Ulker Tamay (Turkey)

Is an oral food challenge mandatory before the introduction of baked goods in food allergic patients? Adrianna Machinena (Spain)

Allergen-specific skin prick testing and IgE values adjusted for cumulative tolerated dose are predictive of oral food challenge outcomes across multiple allergens R. Sharon Chinthrajah (United States)

A novel approach to food allergy diagnosis within a primary prevention trial Maeve M. Kelleher (United Kingdom)

Do threshold data from food challenges reflect real-life allergen exposure? Olaya Alvarez Garcia (Spain)

Perilla seed allergy in 22 children: Clinical characteristics and results of skin prick test Sooyoung Lee (South Korea)

Predicting eliciting dose at food challenge using epitope mapping in peanut-allergic children Paul J Turner (United Kingdom)

Skin prick test predictive values for the outcome of cashew challenges in children Vicki Mcwilliam (Australia)

Digital supported diagnostics in food allergy by analyzing app-based diaries Norbert Roesch (Germany)

Oral immunotherapy with egg peptides induces innate and adaptive tolerogenic responses MÓNICA MARTÍNEZ BLANCO (Spain)

Probiotic peanut oral immunotherapy (PPOIT) induced long-term sustained unresponsiveness is associated with reduced peanut-specific humoral immune responses Mimi L. K. Tang (Australia)

Kinetics of activation of peanut-specific effector and regulatory CD4+ T cells Daniel Lozano-Ojalvo (Spain)

Functional and phenotypic analysis of allergen-specific B cells in cow’s milk allergy and tolerance Pattraporn Satitsuksanoa (Switzerland)

Red meat allergic patients have specific TH2 derived cellular and humoral responses against ixodes ricinus tick proteins supporting the link to a-gal allergy Danijela Apostolovic (Sweden)

Drug allergy > Allergy diagnosis and systems medicine

Poster Discussion Sessions (PDS)

PDS 05 Optimizing diagnosis of drug hypersensitivity Sunday, 2 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Marina Atanaskovic-Markovic (Serbia) Ozge Soyer (Turkey)

The limited value of routinely performing prolonged drug challenges in penicillin hypersensitivity Didier G. Ebo (Belgium)

Changing pattern of positive penicillin skin test from 1998 to 2017 in a large united states medical center Dayne Henry Voelker (United States)

Diagnostic accuracy of skin tests in patients with a penicillin allergy label: A systematic review with meta-analysis and meta-regression Bernardo Manuel Sousa-Pinto (Portugal)

Cross-reactivity in hypersensitivity reactions to cefazolin Jose Julio Laguna (Spain)

Basophil activation test in the diagnosis of hypersensitivity reactions to quinolones: A clinical practice study David Enrique Loli Ausejo (Spain)

Basophil activation tests in the diagnosis of IgE-mediated drug allergy to quinolone and Beta-Lactam antibiotics Iryna Ramanava (Belarus)

Allergy evaluation in patients with selective hypersensitivity to clavulanate Leah Landaveri Sanchez (Spain)

The factors associated with diagnostic skin test positivity in immediate type hypersensitivity reactions due to proton pump inhibitors Sevim Bavbek (Turkey)

Skin tests and challenge-based drug allergy diagnosis: A retrospective study of patients with confirmed drug allergy Ana Margarida Pereira (Portugal)

Patch testing for the investigation of non-immediate cutaneous adverse drug reactions: Results from a prospective quality improvement initiative Timothy J Watts (United Kingdom)

Only the skin test is enough? Cosmin Boteanu (Spain)

Review of completed drug allergy challenges in a one-year period at kings college hospital clinical immunology and allergy service Zoe Adhya (United Kingdom)

Clinical pattern and allergological workup of hypersensitivity reactions proton pump inhibitors Evangelia Chytiroglou (Greece)

Precision medicine and framework for chlorhexedine IgE sensitization Douwe de Boer (The Netherlands)

Dermatology > Pediatrics > Clinical Immunology > Clinical Allergology

Poster Discussion Sessions (PDS)

PDS 06 New concepts of urticaria and angioedema Sunday, 2 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Jose Luis Garcia-Abujeta (Spain) Musa Khaitov (Russia)

Angioedema in patients with chronic spontaneous urticaria is not so mild Marta Ferrer (Spain)

Activation of the coagulation cascade and response to omalizumab in patients with severe chronic spontaneous urticaria Riccardo Asero (Italy)

Cutaneous mast cell numbers are increased in patients with cholinergic urticaria Sabine Altrichter (Austria)

A histopathological comparison of chronic spontaneous urticaria and urticarial vasculitis Viktoria Puhl (Germany)

Transcriptome and immunohistochemistry expression of platelet activating factor receptor (PAF-R) in lesional skin (wheal) of chronic spontaneous urticaria (CSU) Ana M Giménez-Arnau (Spain)

Interleukin-18 binding protein plays a different role in anaphylaxis compared with acute urticaria in children Jin Tack Kim (South Korea)

Autologous serum skin test and basophil activation test: Are the same or different phenomena? Lobna Abdelaziz El-Korashi (Egypt) Clinical characteristic and autoimmune conditions in CSU adult colombian caribbean patients Eduardo Egea (Colombia)

Rilonacept treatment in cold urticaria – results of a randomized, placebo-controlled study Karoline Krause (Germany)

Cold urticaria – characterizing the population from an urticaria outpatient clinic in portugal Marisa Paulino (Portugal)

AWARE: Prospective study of disease burden, quality of life (QoL) and treatment patterns among patients with chronic urticaria Rikke Dodge (Denmark)

Correlation between quality of life (CU-Q2 OL) and degree activity (UAS7) in patients with spontaneous chronic urticaria Diana Andrea Herrera Sánchez (Mexico)

Sister Society Symposia (SSS)

SSS 2 EAACI - GA2LEN Joint Symposium: Pollution and allergies – Planetary health, a new aspect in precision medicine Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 14 (FIL)

Chair Giorgio Walter Canonica (Italy)

What is known about allergic rhinitis and conjunctivitis in correlation to city and rural dwelling Michael Makris (Greece)

The effects of pollution on allergic skin disease Peter Schmid-Grendelmeier (Switzerland)

How GA²LEN ADCARE and UCARE initiatives can support the future of planetary health Torsten Zuberbier (Germany)

Digital transformation of health to sustain planetary health Jean Bousquet (France)

Food allergy > Basic Allergology > Pediatrics > Precision Medicine

Symposia (SYM)

SYM 5 Presidential symposium – Practall 2018 – Immune modulation for food allergy Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 1 (Altice Arena)

Chairs Ioana Octavia Agache (Romania) Kari Christine Nadeau (United States)

Endotype-driven approach for immune modulation in food allergy Wayne G Shreffler (United States)

Prevention of food allergy - a realistic target? George du Toit (United Kingdom) Efficacy, safety and monitoring of current treatment modalities Nonhlanhla Lunjani (Ireland)

Pediatrics > Clinical Allergology > Allied health and primary care

Symposia (SYM)

SYM 6 Overcoming the challenges in adolescent and young adults with allergies Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 2 (Altice Arena)

Chairs Charlotte G. Mortz (Denmark) Pedro Carreiro-Martins (Portugal)

Challenges faced by adolescents, young adults and their healthcare professionals Claudia Gore (United Kingdom)

Why are adolescents and young adults at risk patients? Audrey DunnGalvin (Ireland)

Helping adolescents and young adults to self-manage their allergies Silvia Sanchez-Garcia (Spain)

Clinical Allergology > Allergy diagnosis and systems medicine > Basic Immunology > Allergen immunotherapy

Symposia (SYM)

SYM 7 Diagnostic issues in insect venom allergy Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 3 (Altice Arena)

Chairs Hanneke Oude Elberink (The Netherlands) Maria Graça Castel-Branco (Portugal)

Diagnostic utility of allergen components in insect venom allergy Thilo Jakob (Germany)

Clinical relevance of basophil activation test in insect venom allergy Gunter Sturm (Austria)

Challenges of allergen immunotherapy: Lessons learnt from horse insect hypersensitivity Eliane Marti (Switzerland)

Environmental and occupational allergy > Asthma > Clinical Allergology

Symposia (SYM) SYM 8 Things you don´t want in the air you breathe Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 4 (Altice Arena)

Chairs Gennaro D'Amato (Italy) André Moreira (Portugal)

Health effects of diesel car exhaust Isabella Annesi-Maesano (France)

Bacteria in ambient air: Bad or good for your health? Jeroen Titus Buters (Germany)

Allergy or sick building syndrome: Moulds and more? Mario Olivieri (Italy)

Allergen immunotherapy > Clinical Allergology > Basic Immunology > Precision Medicine

Symposia (SYM)

SYM 9 New insights in allergen immunotherapy: Peptides and beyond Sunday, 2 June 2019

13:30-15:00 hrs Room Hall 9 (FIL)

Chairs Mark Larché (Canada) Oliver Pfaar (Germany)

B cells peptides using molecular approaches for allergen immunotherapy Rudolf Valenta (Austria)

Combined T and B cell peptides for allergen immunotherapy Mohamed Shamji (United Kingdom)

Predictive airway biomarkers of allergen immunotherapy outcomes Ulrich Matthias Zissler (Germany)

Precision Medicine > Asthma > ENT > Clinical Allergology

Thematic Symposia (TSYM)

TSYM 2 Implementing precision medicine for asthma: Are we there yet? Sunday, 2 June 2019

13:45-15:00 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Jasper Kappen (The Netherlands) Matteo Bonini (Italy)

Treatable traits in chronic airway diseases - where do we stand? Zuzana Diamant (The Netherlands)

Subphenotyping eosinophilic asthma – towards new treatment targets? Kian Fan Chung (United Kingdom) Applying precision medicine in pediatric severe asthma: Challenges and opportunities Susanne Vijverberg (The Netherlands)

Highlights Sessions (HS)

HS 1 Highlights on Asthma: Addressing over-reliance on chronic oral corticosteroids treatment in patients with asthma Sunday, 2 June 2019

15:05-15:20 hrs Room Pro & Con Arena (FIL)

Chair Stefano R Del Giacco (Italy)

Interview on the topic: "Addressing over-reliance on chronic oral corticosteroids treatment in patients with asthma" Enrico Heffler (Italy)

Company Sponsored Symposia (CSS)

CSS 4 Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 5 (Altice Arena)

Ocular Allergy > Clinical Allergology

Interactive Workshops (IWS)

IWS 3 Management and diagnosis of the red eye Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 6 (Altice Arena)

Chairs Virginia Lysbeth Calder (United Kingdom) Jean-Luc Fauquert (France)

What differential diagnosis of allergic conjunctivitis should I consider? Serge Doan (France)

How can an ophthalmologist help me to manage my patient with allergic conjunctivitis? Diana Margarida Silva (Portugal)

Biologicals > Clinical Allergology > Precision Medicine

Junior Members Assembly Symposia (JMA SYM) JMA Sci JMA Scientific Symposium: Biologicals and personalized medicine: A new hope Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 7 (Altice Arena)

Chairs Susanne Vijverberg (The Netherlands) Florentina Sava (United Kingdom)

Chronic rhinosinusitis Marjolein Cornet (The Netherlands)

Asthma Anirban Sinha (The Netherlands)

Food allergy Canting Guo (United States)

Skin allergy Pasquale Comberiati (Italy)

Pediatrics > Dermatology > Drug allergy

Oral Abstract Sessions (OAS)

OAS 08 Pediatric cutaneous diseases and drug allergy Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 9 (FIL)

Chairs Susan Chan (United Kingdom) Marina Atanaskovic-Markovic (Serbia)

Session roadmap Susan Chan (United Kingdom)

Impact of different definitions of atopic dermatitis on phenotyping the long-term course of the disease Toshinori Nakamura (Japan)

Food allergens in skin care products marketed for children Ieva Polianskyte (Lithuania)

The efficacy and safety of the up-dosing of second-generation H1 antihistamine in treatment of chronic spontaneous urticaria in a paediatric population Lucrezia Sarti (Italy)

Aetiopathogenesis of severe cutaneous adverse reactions (SCARS) in children: A 9-year experience in a tertiary-care paediatric hospital setting Francesca Mori (Italy)

Evaluation of hypersensitivity reactions to cancer chemotherapeutic agents in childhood Irem Turgay Yagmur (Turkey)

Negative predictive value of five-day drug provocation test for non-immediate beta-lactam allergy in children Ilknur Kulhas Celik (Turkey)

Environmental and occupational allergy Oral Abstract Sessions (OAS)

OAS 09 Damaging effects of air pollutants and climate change Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 11 (FIL)

Chairs Gennaro D'Amato (Italy) Carmen Galán (Spain)

Session roadmap Gennaro D'Amato (Italy)

Effects of air pollutants on pulmonary function in children monitoring by mobile phone application I-Jen Wang Wang (Taiwan)

Modification of effect between air pollution and lung function by the inflammatory potential of diet: A cross sectional study in children Francisca De Castro Mendes (Portugal)

Climate change and air pollution their impact on atopic dermatitis patients Vincenzo Patella (Italy)

Does air pollution affect pollen concentrations through radiative feedback in the atmosphere? Carsten Ambelas Skjoth (United Kingdom)

Microbiota change in mice lung exposed to air pollutants An-Soo Jang (South Korea)

Associations between outdoor of PM2.5 with cough and wheeze symptoms in asthmatic children in Korea Woo Kyung Kim (Pediatrician) (South Korea)

Asthma > Precision Medicine > Biologicals > Clinical Allergology

Oral Abstract Sessions (OAS)

OAS 10 Targeting severe asthma Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 12 (FIL)

Chairs Ioana Octavia Agache (Romania) Matteo Bonini (Italy)

Session roadmap Ioana Octavia Agache (Romania)

Dupilumab reduces oral corticosteroid (OCS) use and severe exacerbations, and improves FEV1 in OCS-dependent, severe asthma with comorbid chronic rhinosinusitis with and without nasal polyps Klaus F. Rabe (Germany)

Dupilumab improves health-related quality of life in patients with oral corticosteroid-dependent, severe asthma with comorbid chronic rhinosinusitis with and without nasal polyps Jorge F. Maspero (Argentina)

Efficacy of omalizumab therapy in asthma patients with or without asthma-related and atopic comorbidities Meng Chen (United States)

Oral corticosteroid-sparing effects of Anti-IL5 And Anti-IL5 receptor treatments. A real-life study Anne Sofie Bjerrum (Denmark)

Oral corticosteroid prescription patterns in asthma care in the UK and Germany Trung N. Tran (United States)

Dietary acid load: A novel nutritional target on the children’s obese-asthma phenotype? Pedro Cunha (Portugal)

Basic Allergology > Basic Immunology > Precision Medicine > Allergy diagnosis and systems medicine

Poster Discussion Sessions (PDS)

PDS 07 Precision allergology Sunday, 2 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Cristobalina Mayorga (Spain) Madeleine Radinger (Sweden)

MicroRNA, a biomarker for allergic rhinitis I-Jen Wang Wang (Taiwan)

Integration of high-dimensional -omics reveals novel predictive signatures and candidate pathways for allergic rhinitis (AR) Anand Kumar Andiappan (Singapore)

In vitro silencing of YRNAs, a potential new tool for studying a epigenetic mechanisms recently described in allergy Ignacio J. Dávila (Spain)

The impact of immune interventions: A systems biology strategy for predicting adverse and beneficial immune effects Jolanda Van Bilsen (The Netherlands)

Transcriptional changes during allergen specific immunotherapy in a mouse model of pru p 3 allergy James Richard Perkins (Spain)

Establishment and validation of basophil histamine release test using highly sensitive LC-MS/MS method for the determination of histamine Cheol Woo Kim (South Korea)

Evaluating potential risks of food allergy from genomic sequences of novel food sources Richard E. Goodman (United States)

A network-based selection of candidate markers and assays to assess the impact of oral immune interventions on gut functions Jolanda Van Bilsen (The Netherlands)

Longitudinal profiling of immunoglobulin heavy-chain repertoires in memory B-cells, plasmablasts and plasma cells from peripheral blood of individuals with birch pollen allergy Artem Ilyich Mikelov (Russia)

CD-sens improves diagnostic accuracy in children sensitized to dog dander Ulrika Käck (Sweden)

Basophil activation test with Pru p 7 is predictive of clinical severity in peach allergic patients Joana Vitte (France, Metropolitan)

Basophil activation test in the diagnosis of cow milk's allergy Amelia Licari (Italy)

Basophil Activation Test In Chronic Spontaneous Urticaria (CSU) Styliani Taka (Greece) Pediatrics > Food allergy > Precision Medicine

Poster Discussion Sessions (PDS)

PDS 08 Pediatric food and hymenoptera venom allergy Sunday, 2 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Giovanni Battista Pajno (Italy) Rodrigo Rodrigues Alves (Portugal)

Can we identify risk factors for non-IgE mediated cow’s milk allergy, presenting as allergic proctocolitis, in preterm and term born infants hospitalized at the NICU? Liselot De Vlieger (Belgium)

Bayesian estimation of risk factors for severe allergic reaction in open oral food challenges in children and adolescents Kazuki Sato (Japan)

The impact of age on histamine skin reactivity Burçin Beken (Turkey)

The ovomucoid/egg white ratio as predictor of tolerance to the boiled egg in the patient allergic Jonnathan Andrés Acevedo Galvis (Spain)

Evaluation of milk and egg oral food challenge outcomes according to cut-off values of skin prick test and food-specific IgE Ilknur Kulhas Celik (Turkey)

Follow-up of introduction of allergenic foods deemed safe in children at high risk or already having a food allergy Molly Cremin (Ireland)

Almond consumption results rarely in allergic reactions but symptoms can be severe Olga Lilith Staudacher (Germany)

Parental support for children with allergies (PASCAL study): A randomised controlled trial of the effectiveness of a self-help website for parents of children with food allergy Christina J Jones (United Kingdom)

The epidemiological study of insect allergy in pediatric practice in Moscow region of Russia Natalia Vyacheslavovna Kobizskaya (Russia)

Insect venom immunotherapy in children in South East England Kleio Kappatou (Greece)

Dermatology > Pediatrics > Biologicals > Clinical Immunology

Poster Discussion Sessions (PDS)

PDS 09 Skin allergy, urticaria and angioedema Sunday, 2 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Luis Miguel Borrego (Portugal) Musa Khaitov (Russia)

Efficacy and safety of long-term treatment with dupilumab for moderate to severe atopic dermatitis Masanori Ikeda (Japan)

Dupilumab improves symptoms of anxiety and depression in adults with moderate-to-severe atopic dermatitis: A post hoc analysis of three phase 3 trials (LIBERTY AD SOLO 1 & 2 And CHRONOS) Zhen Chen (United States)

Dupilumab-related blepharoconjunctivitis in patients with severe atopic dermatitis Angele Soria (France)

JAK1/3-inhibition preserves epidermal morphology in full thickness 3D skin models of atopic dermatitis and psoriasis Inge Kortekaas Krohn (Belgium)

Direct assessment of skin epidermal barrier by electrical impedance spectroscopy (Late Breaking Abstract) Arturo Rinaldi (Italy)

Treatment with combination of Omalizumab and Immuno-suppressor and high dose anti-histamine for resistant severe Chronic Spontaneous Urticaria (Late Breaking Abstract) Ramit Maoz-Segal (Israel)

Novel development in the basic management of atopic dermatitis (Late Breaking Abstract) Roman J. Nowicki (Poland)

Quality of life of people with atopic dermatitis in Asian countries: A systematic review (Late Breaking Abstract) Jinghui Huang

Factors affecting response and recurrence in omalizumab treatment (Late Breaking Abstract) Aytül Sin (Turkey)

Adverse effects of cyclosporin use in patients with severe atopic dermatitis (Late Breaking Abstract) Giovanna Lucy Cortez Aliaga (Brazil)

Clinical phenotype of CSU in association with diabetes may need individual diagnostic and therapeutic approach (Late Breaking Abstract) Daria Fomina (Russia)

Shortage in France of plasma derived C1Inh concentrates: state of play and consequences for patients (Late Breaking Abstract) Laurence Bouillet (France)

The impact of pregnancy in patients with hereditary angioedema – a Portuguese sample (Late Breaking Abstract) Afonso Caires (Portugal)

Allergen immunotherapy > Precision Medicine > Food allergy > Clinical Allergology

Poster Discussion Sessions (PDS)

PDS 10 Allergen immunotherapy in the clinic Sunday, 2 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Mohamed Shamji (United Kingdom) Carmen Vidal (Spain)

Efficacy of the SQ Tree SLIT-tablet assessed by the combined symptom and medication score (CSMS) recommended by the EAACI Tilo Biedermann (Germany) Comparison of the efficacy of single or double-species mite allergen immunotherapy in allergic rhinitis: A prospective randomized controlled study Mason Xue (China)

Evaluation of asthma symptoms in subjects treated with the SQ Tree SLIT-tablet Frédéric de Blay (France)

Evaluation Of SLIT Class Effects Across The SQ Tree SLIT-Tablet Development Programme Mandy Cuevas (Germany)

Extensive CD4+ T-Cell cross-reactivity within homologous allergen groups of temperate grasses and Peter Adler Würtzen (Denmark)

IgE and IgG4 response uniformity allows for subject-specific measure of exposure to sublingual allergen immunotherapy Peter Sejer Andersen (Denmark)

Long-term clinical efficacy of HDM allergen immunotherapy in allergic rhinitis Peiyan Zheng (China)

Nasal provocation test and immunological changes after 1 year treatment with a dermatophagoides pteronyssinus allergoid associated with microcrystalline tyrosine, in patients with allergic rhinitis José Luis Justicia (Spain)

Optimal dosing strategy of omalizumab in oral immunotherapy Maxime Paquin (Canada)

Peanut allergen immunotherapy: Assessment of clinical practices and knowledge among allergist Nimish Mehta (United States)

Resource use in tree pollen allergy: SQ Tree SLIT-tablet treatment effect on patients’ use of symptom-relieving medication Adam M Chaker (Germany)

Safety and treatment persistence of subcutaneous immunotherapy: A 30-year retrospective study Danilo Di Bona (Italy)

Safety of dual SLIT with Japanese cedar pollen and SQ house dust mite sublingual immunotherapy tablets Mitsuhiro Okano (Japan)

Safety results of the first SQ HDM SLIT-tablet trial in chinese subjects with house dust mite allergic rhinitis Marianne Witten (Denmark)

T-cells specific to dominant Bet V 1 peptides are highly cross-reactive towards corresponding peptides from group 1 allergens of the homologous group of tree and Peter Adler Würtzen (Denmark)

Sister Society Symposia (SSS)

SSS 3 EAACI – APAPARI Joint Symposium: Role of hygiene, microbiome and biodiversity in allergies - the untold stories from around the world Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Pakit Vichyanond (Thailand) Motohiro Ebisawa (Japan)

Role of microbiome in childhood eczema Ting Fan Leung (Hong Kong SAR)

Nasal microbiota and allergic airway disorders in early childhood Lynette Shek (Singapore)

Role of gut microbiotia and development of allergies Christina E West (Sweden)

Pediatrics > Clinical Allergology > Clinical Immunology > Allied health and primary care

Symposia (SYM)

SYM 10 How to manage patients with drug hypersensitivity? Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 1 (Altice Arena)

Chairs Maria J Torres (Spain) Eva Gomes (Portugal)

Non-betalactams antibiotics Ozge Soyer (Turkey)

Antiepileptic drugs Jean-Christoph Caubet (Switzerland)

Chemotherapeutics Josefina Maria Rodrigues Cernadas (Portugal)

Food allergy > Allergen immunotherapy > Pediatrics > Precision Medicine

Symposia (SYM)

SYM 11 Novel therapeutic approaches for food allergy Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 2 (Altice Arena)

Chairs Kirsten Beyer (Germany) Kari Christine Nadeau (United States)

Use of allergoids in food allergy Margitta Worm (Germany)

Sublingual and subcutaneous allergen immunotherapy in food allergy Barbara Bohle (Austria)

Recombinant allergens to treat food allergy Ronald van Ree (The Netherlands)

Asthma > Basic Immunology > Clinical Immunology

Symposia (SYM) SYM 12 Asthma immunology and inflammation: New insights Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 3 (Altice Arena)

Chairs Stefano R Del Giacco (Italy) Mariana Couto (Portugal)

The emerging role of innate lymphoid cells (ILCs) in asthma Kornel Golebski (The Netherlands)

The epithelial dysfunction Brecht Steelant (Belgium)

The microRNAs as regulators of the inflammatory response Victoria del Pozo (Spain)

Clinical Allergology > ENT > Allergen immunotherapy > Precision Medicine

Symposia (SYM)

SYM 13 How smartphone apps can help allergy management? Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 4 (Altice Arena)

Chairs Karin Hoffmann-Sommergruber (Austria) Mikhail Sofiev (Finland) mHealth technology and allergic rhinitis control Jean Bousquet (France)

How digital solutions contribute to better control of patient outcomes in chronic respiratory diseases Gert Marien (Belgium) mHealth-Technology and allergen immunotherapy Paolo Matricardi (Germany)

ENT > Clinical Allergology

Year in Review Sessions (YIR)

YIR 2 Year in Review: ENT Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 10 (FIL)

Chairs Joaquim Mullol (Spain) Peter Hellings (Belgium)

Chronic rhinosinusitis with nasal polyps: Insight into novel mechanisms of disregulation Claus Bachert (Belgium)

Novel treatment approaches in chronic rhinositis with/without nasal polyps and rhinitis Sanna Toppila-Salmi (Finland) Regulators of NSAID-exacerbated respiratory disease Martin Wagenmann (Germany)

Clinical Immunology

Year in Review Sessions (YIR)

YIR 3 Year in Review: Basic and Clinical Immunology Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 13 (FIL)

Chairs Jürgen Schwarze (United Kingdom) Milena Sokolowska (Switzerland)

Innate immunity Henry McSorley (United Kingdom)

T- and B-cells Stefanie Eyerich (Germany)

Epithelial barriers Jan Gutermuth (Belgium)

Dermatology

Year in Review Sessions (YIR)

YIR 4 Year in Review: Dermatology Sunday, 2 June 2019

15:30-17:00 hrs Room Hall 14 (FIL)

Chairs Knut Brockow (Germany) Désirée Erlinda Sophia Larenas-Linnemann (Mexico)

Atopic dermatitis Dagmar Simon (Switzerland)

Allergic contact dermatitis Jeanne Duus Johansen (Denmark)

Urticaria and angioedema Martin Metz (Germany)

Business Meetings (BM)

BM 5 Interest Group Allergen Immunotherapy - Open to all attendees Sunday, 2 June 2019 17:30-18:40 hrs Room Hall 4 (Altice Arena)

Introductory lecture: Prevention of asthma in children with AIT: How to implement new AIT guidelines in clinical practice? Susanne Halken (Denmark)

Business Meetings (BM)

BM 6 Interest Group Food Allergy - Open to all attendees Sunday, 2 June 2019

17:30-18:40 hrs Room Hall 11 (FIL)

Introductory lecture: Modifications of allergens – friend or foe (hydrolysates, GMO, heat, matrix, chemical modification) Clare Mills (United Kingdom)

Report on current activities, MW and BB

Presentation CM

Board meeting with new elected board members

Business Meetings (BM)

BM 7 Interest Group Allergy Diagnosis & System Medicine - Open to all attendees Sunday, 2 June 2019

17:30-18:40 hrs Room Hall 12 (FIL)

Introductory lecture: Mobile health technologies in allergy care: The EAACI 2019 position paper Stephanie Dramburg (Germany)

Minutes approval (BE)

TF updates

Focused Meetings

Congresses

Working groups

Any other business [PM]

Next TC date [BE]

Business Meetings (BM) BM 8 JM Assembly - Open to all attendees Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 14 (FIL)

Chairs Ibon Eguiluz-Gracia (Spain) Carmen Riggioni (Spain)

Introductory lecture: The era of e-health: New opportunities for research and care through mobile technologies Jean Bousquet (France)

Report from the chair and evaluation of the 2017-2019 term Ibon Eguiluz-Gracia (Spain)

News from the Basic & Clinical Immunology Section Florentina Sava (United Kingdom)

News from the Asthma Section Susanne Vijverberg (The Netherlands)

News from the Pediatrics Section Pasquale Comberiati (Italy)

News from the Dermatology Section Alberto Alvarez-Perea (Spain)

News from the ENT Section Peter Valentin Tomazic (Austria)

News from the Interest Groups Alberto Alvarez-Perea (Spain)

Introduction of the 2019-2021 JMA Board Carmen Riggioni (Spain)

Satellite Symposia (SAT)

SAT 1 Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 3 (Altice Arena)

Satellite Symposia (SAT)

SAT 2 Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 5 (Altice Arena)

Satellite Symposia (SAT)

SAT 3 Sunday, 2 June 2019 17:30-19:00 hrs Room Hall 7 (Altice Arena)

Satellite Symposia (SAT)

SAT 4 Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 8 (FIL Meeting Centre)

Satellite Symposia (SAT)

SAT 5 Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 9 (FIL)

Satellite Symposia (SAT)

SAT 6 Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 10 (FIL)

Sister Society Symposia (SSS)

SSS 4 EAACI – ACAAI Joint Symposium: Challenges in pediatric allergy Sunday, 2 June 2019

17:30-19:00 hrs Room Hall 2 (Altice Arena)

Chair Bryan L. Martin (United States)

Exploring the challenges of anaphylaxis in infants and toddlers James L Sublett (United States)

Burden of atopic dermatitis in children and their caregivers Michael S. Blaiss (United States)

Update in asthma management and control Todd A. Mahr (United States)

Ocular Allergy

Learning Lounges (LL) LL 5 Treatment options in severe ocular allergy Monday, 3 June 2019

07:00-07:45 hrs Room Hall 11 (FIL)

Treatment options in severe ocular allergy Andrea Leonardi (Italy)

Allied health and primary care

Learning Lounges (LL)

LL 6 Educating the food allergic patient for a better quality of life: Practical issues Monday, 3 June 2019

07:00-07:45 hrs Room Hall 12 (FIL)

Educating the food allergic patient for a better QOL: Practical issues Emilia Vassilopoulou (Cyprus)

Allergy diagnosis and systems medicine > Precision Medicine

Learning Lounges (LL)

LL 7 Implement component-resolved diagnostics in allergy Monday, 3 June 2019

07:00-07:45 hrs Room e-Poster Area A (FIL)

Implement component-resolved diagnostics in allergy Jörg Kleine-Tebbe (Germany)

Asthma > Precision Medicine

Learning Lounges (LL)

LL 8 Treatable traits in asthma: Can it predict exacerbations? Monday, 3 June 2019

07:00-07:45 hrs Room e-Poster Area C (FIL)

Treatable traits in asthma: Can it predict exacerbations? Jasper Kappen (The Netherlands) EAACI General Assembly

GA EAACI General Assembly - EAACI members only Monday, 3 June 2019

08:00-09:00 hrs Room Hall 3 (Altice Arena)

Basic Immunology > Basic Allergology > Clinical Allergology > Allergen immunotherapy

Plenary Symposia (PL)

PL 3 Fueling the immunity: From immunometabolism to novel treatment strategies Monday, 3 June 2019

09:00-10:30 hrs Room Hall 1 (Altice Arena)

Chairs Carsten Schmidt-Weber (Germany) Eva Untersmayr (Austria)

Innate immune cells and immunometabolism for novel therapeutic interventions Adam Byrne (United Kingdom)

Metabolic reprogramming in T cells as a target of immunotherapy Domingo Barber (Spain)

Translating novel concepts in metabolomics into allergy interventions Milena Sokolowska (Switzerland)

Asthma > Biologicals > Basic Allergology > Precision Medicine

Plenary Symposia (PL)

PL 4 Bio-”logic” approaches in asthma Monday, 3 June 2019

09:00-10:30 hrs Room Hall 2 (Altice Arena)

Chairs Zuzana Diamant (The Netherlands) Guy Scadding (United Kingdom)

Type 2 targeted therapies: Biologicals versus small molecules Shuaib Nasser (United Kingdom)

Non-type 2 asthma: Clinical approach and treatment options Parameswaran Nair (Canada)

Current biological options for children with asthma and future opportunities Jocelyne Just (France)

Basic Immunology > Clinical Immunology > Clinical Allergology > Allergen immunotherapy Thematic Symposia (TSYM)

TSYM 3 Immune regulation in health and airway disease Monday, 3 June 2019

10:45-12:00 hrs Room Hall 4 (Altice Arena)

Chairs Darío Antolín-Amérigo (Spain) Luis Taborda-Barata (Portugal)

Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans Kornel Golebski (The Netherlands)

Bystander tolerance and immune deviation after Fel d 1 peptide immunotherapy Mark Larché (Canada)

Control of T Cell Metabolism and Inflammation by Reactive Oxygen Species Dirk Brenner (Luxembourg)

Company Sponsored Symposia (CSS)

CSS 5 Monday, 3 June 2019

10:45-12:15 hrs Room Hall 14 (FIL)

Clinical Immunology > Basic Allergology

Hot Topic Sessions (HT)

HT 3 Advances in immunologic aspects of allergic diseases Monday, 3 June 2019

10:45-12:15 hrs Room Hall 13 (FIL)

Chairs Edward Frank Knol (The Netherlands) Hideaki Morita (Japan)

Epithelial damage and tissue γδ T cells promote a unique and targeted IgE response Jessica Strid (United Kingdom)

Allergic inflammatory memory in human respiratory epithelial progenitor cells José Ordovas-Montañes (United States)

Innate lymphoid cells in allergy and immune tolerance Suzanne Bal (The Netherlands)

Basic Allergology > Basic Immunology > Clinical Immunology Interactive Workshops (IWS)

IWS 4 Forgotten and new players of immune responses: Lipid mediators Monday, 3 June 2019

10:45-12:15 hrs Room Hall 6 (Altice Arena)

Chairs Milena Sokolowska (Switzerland) Domingo Barber (Spain)

The balance of prostaglandins and leukotrienes: Impact in allergy? Grzegorz Woszczek (United Kingdom)

Cannabinoids in allergic responses: Friends or foes? Oscar Palomares (Spain)

Basic Immunology > Dermatology > Pediatrics > Asthma

Late Breaking Poster Discussion Sessions (LB PDS)

LB PDS 03 Novel insights in allergy and clinical immunology Monday, 3 June 2019

10:45-12:15 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Jan Gutermuth (Belgium) Norma Rubini (Brazil)

Increase of IgE+ lymphocytes in allergic patients after allergen exposure: A possible target for allergy treatment Maria Byazrova

Sleep problems are common and burdensome in patients with allergic rhinitis with or without allergic asthma Mercedes Romano (Denmark)

Characteristics of perennial allergy sufferers prescribed allergy treatment Mercedes Romano (Denmark)

Structural and functional insights into the ligelizumab/IgE interaction Michaela Miehe (Denmark)

Naturally-occurring autoantibodies against human chorionic gonadotropin (hCG) and its subunits in patients with benign ovarian tumours Nino Chikadze

Rapid low-cost microarray-based genotyping for genetic screening in primary immunodeficiency Narissara Suratannon (The Netherlands)

Intravenous human immunoglobulin infusion adverse effects in patients with immunodeficiency Giovanna Lucy Cortez Aliaga (Brazil)

Depression in hereditary angioedema can cause sexual morbidity Emine Nihal Mete Gokmen (Turkey)

Association between beta-defensin 2 in breastmilk with the risk of atopic dermatitis onset in children Oxana A. Svitich (Russia)

Soluble FceRI disrupts cell-bound chimeric IgE Sonja Kopanja (Serbia)

Association of pancreatic tumor markers to viral hepatitis infections Nino Chikadze

Primary infection of vascular endothelium with human rhinovirus HRV16 may induce and sustain cellular anti-viral resistance Maciej Chalubinski (Poland)

Alt a 1 induces immune response in bronchial epithelial cells through SLC22A17 María Garrido-Arandia (Spain)

Environmental and occupational allergy

Oral Abstract Sessions (OAS)

OAS 11 Sensitization and geographical diversity of airborne allergens Monday, 3 June 2019

10:45-12:15 hrs Room Hall 9 (FIL)

Chairs Michel Thibaudon (France) Jeroen Titus Buters (Germany)

Session roadmap Michel Thibaudon (France)

High-throughput DNA sequencing defines spatiotemporal shifts in airborne grass pollen communities at species level Gareth W Griffith (United Kingdom)

Assessing quantitative taxon-specific grass pollen biodiversity in time and space using targeted molecular analysis of aerial environmental DNA Simon Creer (United Kingdom)

Sensitization to holm oak and plane tree pollen and cross-reactivity patterns with grasses of a university student population in Évora, Portugal Celia Maria Antunes (Portugal)

Molecular sensitisation profile to Dermatophagoides pteronyssinus dust mite in Portugal Rita Limão (Portugal)

Molecular data of pollen sensitization corresponds with pollen spectrum of Ukraine Victoria Rodinkova (Ukraine)

Evaluating the real exposure of allergics to airborne pollen: Too high, too early, too long or too complex? Athanasios Damialis (Germany)

Clinical Immunology

Oral Abstract Sessions (OAS)

OAS 12 New perspectives from clinical trials in immunodeficiencies Monday, 3 June 2019

10:45-12:15 hrs Room Hall 10 (FIL)

Chairs Isabella Quinti (Italy) Gunnur Deniz (Turkey)

Session roadmap Isabella Quinti (Italy)

Association between severe IgA immunodeficiency and allergic and respiratory disorders in children Jelena Živkovic (Croatia)

Low dose azitromycin prophylaxis reduces respiratory exacerbations in primary antibody deficiencies: A multicenter, double-blind, placebo-controlled randomized clinical trial Cinzia Milito (Italy)

BCG vaccine-associated complications and clinical course following allogeneic bone marrow transplantation in patients with primary immunodeficiency diseases Adeeb Nasser Eldin (Palestine)

Impact of the route of immunoglobulin administration on health-related quality of life in patients with CVID: A prospective multicenter study Federica Pulvirenti (Italy)

Autoimmunity and lymphoproliferation: Different or converging phenotypes in common variable immunodeficiencies? Cláudia Viseu Varandas (Portugal)

Precision Medicine > Basic Allergology > Allergy diagnosis and systems medicine

Oral Abstract Sessions (OAS)

OAS 13 Molecular features of allergens Monday, 3 June 2019

10:45-12:15 hrs Room Hall 11 (FIL)

Chairs Adriano Mari (Italy) Rudolf Valenta (Austria)

Session roadmap Adriano Mari (Italy)

The crystal structure of the major olive pollen allergen Ole E 1 elucidates the dimeric nature of the allergen and explains its high allergenicity Judith Wortmann (Germany)

Pru P 7 is a major peach allergen associated with cypress pollen sensitization and increased risk of severe reactions Caroline Klingebiel (France)

Assessment of Tri a 14 sensitization in the routine allergological study: Analysis of currently available diagnostic tools efficiency CLARA SAN BARTOLOMÉ BELLOCH (Spain)

N-terminal vicilin domains are major allergens in walnut Bo Pontoppidan (Denmark)

Intermolecular association of peanut allergens and the impact of thermal processing Abigail S Burrows (United States)

CCD interference in the diagnosis of allergy to shellfish and parasitic helminths Wolfgang Hemmer (Austria)

Asthma > Clinical Allergology > Basic Allergology Oral Abstract Sessions (OAS)

OAS 14 Molecular mechanisms of allergic diseases Monday, 3 June 2019

10:45-12:15 hrs Room Hall 12 (FIL)

Chairs Ibon Eguiluz-Gracia (Spain) Enrico Heffler (Italy)

Session roadmap Ibon Eguiluz-Gracia (Spain)

Establishment of an allergic lung inflammation mouse model for pre-clinical testing of novel anti-human IgE drug candidates Pascal Gasser (Switzerland)

MARCKS family proteins are altered in naturally occurring model of asthma in horses. Kaori Uchiumi Davis (United States)

Metabolic characterization of epithelial barrier damage caused by Der P 1 Alma Villaseñor Solis (Spain)

Cadherin-related family member 3 upregulates the effector functions of eosinophils Kazuyuki Nakagome (Japan)

EQTL and gene expression analyses using whole genome sequence and RNAseq identify three independent signals in Chr17q region associated with asthma and asthma exacerbations Xingnan Li (China)

Swimming pool training environment may drive skin and gut dysbiosis in elite swimmers Inês Ribeiro Paciência (Portugal)

Allergen immunotherapy > Allied health and primary care > Basic Allergology > Food allergy

Poster Discussion Sessions (PDS)

PDS 11 Mechanisms of allergen immunotherapy Monday, 3 June 2019

10:45-12:15 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Adam M Chaker (Germany) Erika Jensen-Jarolim (Austria)

IgE-and T-cell cross-reactivity towards birch homologous tree pollen allergens confirmed by changes in IgE and IgG4 antibody responses during SQ Tree SLIT-tablet treatment Peter Adler Würtzen (Denmark)

IgE signaling repression by a designer DNA vaccine to modulate shrimp hypersensitivity Ka Hou Chu (Hong Kong SAR)

Prophylactic effects of virus like particles displaying the major HDM allergen Der P 2 in a mouse model of HDM allergy Alain Jacquet (Thailand)

Adoptive transfer of type 1 regulatory T (Tr1) cells suppresses development of airway hyperresponsiveness in a murine model of asthma Masaya Matsuda (Japan)

Effects of IL-4 receptor a blockade during allergen-specific immunotherapy in a murine model of allergic asthma Sonja Heine (Germany)

Carbohydrate-protein conjugates for allergen-specific immunotherapy Evgeniia Korotchenko (Austria)

Effects of subcutaneous immunotherapy (SCIT) on the numbers of IL-10-producing CD4+ T cells and IL-10-producing B cells in peripheral blood of pollinosis patients Tetsuya Terada (Japan)

Immunomodulation of CD4+CXCR5+PD-1+ T Follicular Helper (Tfh) and CD4+CXCR5+PD-1+FoxP3+ T follicular regulatory (Tfr) cell responses in grass pollen allergy YI YI (United Kingdom)

Development of a competitive IgG binding assay for the potency determination of allergoid-based allergen preparations of house dust mites Kerstin Bauermeister (Germany)

Impact of local innate lymphoid cells type 2 (ILC2) in allergic rhinitis and asthma patients Ulrich Matthias Zissler (Germany)

Comparison of the allergenic activity of different mite standardized antigenic extract containing the body or the whole mite extract: An in vitro study Moises Labrador-Horrillo (Spain)

Protection against pollen allergy and asthma in blood donors by pre-seasonal oral supplementation with an immunomodulatory agaricus blazei-based mushroom extract: A randomized placebo-controlled study Geir Hetland (Norway)

Randomized controlled phase 2a study results using anti IL-33 in food allergy Cherie Liu (United States)

Asthma > Precision Medicine

Poster Discussion Sessions (PDS)

PDS 12 Biomarkers in asthma Monday, 3 June 2019

10:45-12:15 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Tari Haahtela (Finland) Cristina Jácome (Portugal)

The role of fractional exhaled nitric oxide in the assessment of athletes reporting exertional dyspnoea Hayden Allen (United Kingdom)

MiRNAs signature in serum: A biomarker for differentiation of asthma against ACO and COPD José Manuel Rodrigo-Muñoz (Spain)

Surfactant protein A and pattern of phospholipids in the lining fluid from healthy subjects and those with asthma Anna-Carin Olin (Sweden)

Diurnal variation in surfactant protein a and albumin in the healthy Spela Kokelj (Sweden)

MicroRNA, environmental exposures, and asthma I-Jen Wang Wang (Taiwan) PAH exposure, DNA methylation, and childhood atopic disorders I-Jen Wang Wang (Taiwan)

Nasal ciliary ultrastructural marker assessment provides a novel approach for endotyping asthma Wei Jie Guan (China)

Analysis of the expression of Th-1, Th-2, Th-17 cytokines in patients with allergic and non-allergic bronchial asthma associated with chronic rhinosinusitis with nasal polyps Miramgul Dyneva (Russia)

An assessment of the usefulness of serum periostin, as a predictor for omalizumab induction in future: Follow-up study of KiHAC population Hironobu Sunadome (Japan)

Stability of serum MicroRNAs as a diagnostic biomarker in asthma Manuel Jorge Rial (Spain)

Fatty acid binding protein 4 is not related to asthma or severity of asthma Semra Demir (Turkey)

Visceral adiposity is associated with cytokines and decrease in lung function in women with persistent asthma Albertina Varandas Capelo (Brazil)

Bronchoalveolar lavage immune profiling reveals heterogeneity of aspirin-exacerbated respiratory disease (AERD) phenotype of asthma Grazyna Bochenek (Poland)

The association of plasma cytokines including VEGF with diagnostic characteristics in allergic patients Woo-Sung Chang (South Korea)

Dermatology > Pediatrics > Clinical Immunology > Biologicals

Poster Discussion Sessions (PDS)

PDS 13 State of the art treatments for angioedema Monday, 3 June 2019

10:45-12:15 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Tabi Leslie (United Kingdom) Timothy Craig (United States)

Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema (HAE) attacks in the phase 3 HELP study: Findings for days 0-69 and at steady state Marcus Maurer (Germany)

Efficacy and quality of life outcomes with long-term subcutaneous C1 inhibitor prophylaxis in the COMPACT open-label extension trial Timothy Craig (United States)

Experience with plasma-derived C1-inhibitor in pregnant women with hereditary angioedema: A systematic review of the literature Joel Brooks (United States)

Early treatment with icatibant reduces the time to onset of symptom relief in children and adolescents with hereditary angioedema (HAE) Henriette Farkas (Hungary)

Use of short term prophylaxis during treatment with lanadelumab does not impact the risk of an attack: Analysis of data from the HELP study and HELP OLE William Raymond Lumry (United States)

Lanadelumab prophylaxis reduces breakthrough hereditary angioedema attacks and the need for rescue medication: Exploratory findings from the phase 3 HELP study Marco Cicardi (Italy)

Treatment outcomes with high frequency versus low frequency icatibant use in the real-world setting: Results from the icatibant outcome survey Hilary J. Longhurst (United Kingdom)

Rapid and sustainable effect of icatibant across recurrent hereditary angioedema attacks in adolescent patients Aharon Kessel (Israel)

A missense mutation of the plasminogen gene in hereditary angioedema with normal C1 inhibitor in Japan Takahiko Horiuchi (Japan)

Omalizumab treatment, re-treatment and step-up treatment associated with reduced angioedema rates: Results from the optima study Gordon Sussman (Canada)

Role of vascular permeability factors in patients with normal C1-INH angioedema Stefania Loffredo (Italy)

A new instrument for the evaluation of premonitory signs and symptoms (Prodromes) of Hereditary Angioedema Iris Leibovich-Nassi (Israel)

Altered metabolism of phospholipases C and diacylglycerols in patients with hereditary angioedema with factor XII mutations Antonio Cocchiaro (Italy)

Clinical and demographic characteristics of patients with hereditary angioedema in eight countries in Europe, North America, and Australia Joan Mendivil (Switzerland)

Nailfold videocapillaroscopic findings in bradykinin-mediated angioedema Azzurra Cesoni Marcelli (Italy)

Sister Society Symposia (SSS)

SSS 5 EAACI – SPAIC and SEAIC Joint Symposium: Towards the best allergy practice Monday, 3 June 2019

10:45-12:15 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Antonio Valero (Spain) Maria Elisa Pedro Fernandes (Portugal)

Safety and quality recommendations for your allergy practice – an expert panel consensus document Carmen Vidal (Spain) mHealth and gamification strategies to improve knowledge and adherence in asthma treatment João Almeida Fonseca (Portugal)

A national survey on allergic diseases - what changed in a decade? Joaquin Sastre (Spain)

Clinical Allergology > Food allergy > Pediatrics

Symposia (SYM) SYM 14 Current and future perspectives in food allergy and anaphylaxis Monday, 3 June 2019

10:45-12:15 hrs Room Hall 1 (Altice Arena)

Chairs Alberto Alvarez-Perea (Spain) Adam Fox (United Kingdom)

What can we learn from the epidemiology of anaphylaxis? Luciana Kase Tanno (Brazil)

Impact of cofactors and comorbidities Paul J Turner (United Kingdom)

Pre, pro and synbiotics in food allergy Alessandro Fiocchi (Vatican City)

Clinical Allergology > Asthma

Symposia (SYM)

SYM 15 Immune response on the move Monday, 3 June 2019

10:45-12:15 hrs Room Hall 2 (Altice Arena)

Chairs Mariana Couto (Portugal) Jasper Kappen (The Netherlands)

Physical activity and immune response: What is the link? Rodolfo de Paula Vieira (Brazil)

The influence of exercise on asthma and allergy Sven F Seys (Belgium)

Impact of exercise on infections: How much is too much? Marcin Kurowski (Poland)

Pediatrics > Biologicals > Dermatology > Precision Medicine

Symposia (SYM)

SYM 16 Biologicals in pregnancy and childhood Monday, 3 June 2019

10:45-12:15 hrs Room Hall 3 (Altice Arena)

Chairs Thomas Eiwegger (Canada) Karin Lødrup Carlsen (Norway)

Safety of biologicals in atopic disease during pregnancy Birgit Pfaller-Eiwegger (Canada)

Anti-IgE therapeutic approaches in children: Where do we stand? Antonio Nieto Garcia (Spain)

Novel biologicals in pediatric atopic dermatitis Susan Chan (United Kingdom)

Food allergy > Pediatrics > Clinical Allergology > Clinical Immunology

Symposia (SYM)

SYM 17 When IgE isn’t the main issue in food allergy Monday, 3 June 2019

10:45-12:15 hrs Room Hall 5 (Altice Arena)

Chairs Isabel Janet Skypala (United Kingdom) George du Toit (United Kingdom)

Food Protein Induced Enterocolitis Syndrome (FPIES): How to manage in the clinic Sonsoles Infante (Spain)

Challenges in the management of non-IgE mediated Food Allergy Hania Szajewska (Poland)

Gluten hypersensitivity in the food allergy clinic Imke Reese (Germany)

Basic Immunology > Clinical Allergology > Clinical Immunology > Dermatology

Symposia (SYM)

SYM 18 Virus infections and drug hypersensitivity Monday, 3 June 2019

10:45-12:15 hrs Room Hall 7 (Altice Arena)

Chairs Jean-Christoph Caubet (Switzerland) Luís Delgado (Portugal)

The impact of immunological response to viruses in allergic inflammation Jürgen Schwarze (United Kingdom)

How to differentiate a viral from a drug-induced exanthema ? Andreas Bircher (Switzerland)

Role of viruses in severe cutaneous adverse drug reaction Marina Atanaskovic-Markovic (Serbia)

Environmental and occupational allergy > Asthma > Pediatrics

Late Breaking Thematic Poster Sessions (LB TPS) LB TPS 04 Air pollution and environmental allergies Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 6 in e-Poster Area A (FIL)

Chairs Michel Thibaudon (France) Carmen Galán (Spain)

In-depth quantitative profiling of post-translational modifications of Timothy grass pollen allergome in relation to environmental pollution and oxidative stress Katarina Smiljanic (Serbia)

Association between sensitization to grasses and molds as cause of exacerbation asthma in autumn Guadalupe Hernández Ramírez (Spain)

Sensitisation and respiratory symptoms induced by a new allergen from Peach tree pollen in children and adolescents. Maria Luisa Somoza (Spain)

Prevalence of Asthma and Obesity and the role of Environmental Factors Revaz Sepiashvili (Russia)

Atmosferic pollutants NO2 and O3 enhance allergenic potential of Dactylis glomerata pollen Ana Rodrigues Costa (Portugal)

Performance of the personalized allergy symptoms forcasting system Olga Ritenberga (Latvia)

Temporal changes in molecular aerobiome diversity by applying DNA metabarcode sequencing across the pollen season Janet Mary Davies (Australia)

Cathelicidin treatment reduces negative changes in the expression of genes involved in pulmonary fibrosis in mice model of hypersensitivity pneumonitis Marta Kinga Lemieszek (Poland)

Important of Aeropolinologic Study in Children With Risk of Respiratory Allergies Revaz Sepiashvili (Russia)

Second and third-hand smoke: Public perceptions of the risks for children’s health Cláudia Bernhardt (Brazil)

The impact of environmental conditions on the expression of the major fungal allergens Alt a 1 and Ulo c 1 – A comparative study on an indoor and outdoor fungal allergen source Sandra Pfeiffer (Austria)

Prophylaxis of allergic rhinitis in the light of own research Joanna Strozek (Poland)

Effect of living environment on IgE sensitization to the non-biting midge (Chironomus flaviplumus, Chironomus kiiensis and Cricotopus bicinctus) Myunghee Yi (South Korea)

Respiratory symptoms induced by two new Peach tree pollen allergens: Pru p 9 and Ole e 6-like Maria Luisa Somoza (Spain)

Aerobiology of plane tree pollen (Platanus hispânica Miller ex Münchh) in Portugal Elsa Caeiro

Environmental and occupational allergy > ENT > Pediatrics > Allergen immunotherapy

Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 05 Airborne allergens and upper airways Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 12 in e-Poster Area B (FIL)

Chairs Peter Valentin Tomazic (Austria) Ralph Mösges (Germany)

Horse sensitization and allergy to mold, pollen, dust and storage mites, and culicoides in a horse population from southern Portugal. Luís Miguel Martins (Portugal)

Expression of estrogen receptor(ER)-a in nasal polyps and the effects of dexamethasone on ER-a expression and apoptosis in RPMI 2650 cells Byoung Joon Baek (South Korea)

The changes of the prevalence of skin prick test in juju island based on a Korean multi-center study CHAN SOON PARK

Differentiating eosinophil and neutrophil inflammation in chronic rhinosinusitis with and without nasal polyps Tim Delemarre (Belgium)

Rhinitis medication use in patients with persistent rhinitis: Belgian cross-sectional study with historical control Sophie Scheire (Belgium)

Allergic factors affect outcomes after endoscopic sinus surgery in patients with chronic rhinosinusitis Cuida Meng (China)

Acceptability and short term efficacy of nasal phototherapy in a small paediatric population, a patient and nursing perspective. Faye Mathias (United Kingdom)

Cytological monitoring of the nasal mucosa in patients with non-allergic vasomotor rhinitis treated with a new nasal spray formulation Simonetta Masieri (Italy)

Allergy and cystic fibrosis – risk factors for chronic rhinosinusitis at child Alina Murgu (Romania)

NAPPREB study protocol: A pivotal clinical trial to investigate clinical efficacy and potential response biomarkers to Benralizumab treatment in chronic rhinosinusitis with nasal polyps Enrico Heffler (Italy)

Glucocorticoid inhalation combined with olfactory training in the treatment of chronic sinusitis olfactory dysfunction qian xiu (China)

Multivariate regression analysis of epistaxis to predisposing site and treatment Cuida Meng (China)

The analysis and study on the classification and clinical features of eosinophilic chronic rhinosinusitis Cuida Meng (China)

Immunotherapy and medication supervision improved quality of life in adult with allergic rhinitis, a longitudinal study qian xiu (China)

Quality of life assessment before and after long-term treatment of allergic rhinitis in adults - ten years Cuida Meng (China)

The analysis and study of allergen features in chronic rhinosinusitis with or without polyps Cuida Meng (China)

Evaluation of olfactory function as a potential biomarker in patients with Mastocytosis MARGHERITA DEIDDA (Italy)

Study of aero-allergens and mites in rural part of Eastern India by skin prick testing Manuprita Sharma (India) Pediatrics > Asthma > Clinical Allergology > Food allergy

Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 06 Risk factors, diagnosis and quality of life in pediatrics Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 18 in e-Poster Area C (FIL)

Chairs Rodrigo Rodrigues Alves (Portugal) João Negreiros Tebyriçá (Brazil)

The value of autonomic status for the control of bronchial asthma at children Vilya Bulgakova (Russia)

Thyroid status at children with bronchial asthma (BA) Vilya Bulgakova (Russia)

MMR immunisation practices in children with a history of egg allergy Elif Karakoc-Aydiner

Risk factors in IgE mediatated alergy in infants – cases study Monica mihaela Alexoae (Romania)

Extrahepatic manifestations with immune mechanism in children with chronic hepatitis Alice nicoleta Azoicai (Romania)

What does mothers of children with food allergy searching on social media? ESRA YUCEL (Turkey)

The influence of atopic risk factors on evolution of subglottic laryngitis in children PAULA POPOVICI (Romania)

Evaluation of sports habits of children with asthma and factors effecting these habits Ilknur Kulhas Celik (Turkey)

Investigation of factors trigerring asthma attack in childhodd Ilknur Kulhas Celik (Turkey)

Allergic and non-allergic comorbidities in pediatric atopic dermatitis ileana ioniuc (Romania)

Quality of life in children aged 8-18 with a diagnosis of confirmed drug hypersensitivity reaction Ilknur Kulhas Celik (Turkey)

Evaluation of underlying etiological factors in children with high serum levels Ozge Soyer (Turkey)

Seeking early-life windows of opportunity to shape lifelong immune health through text mining Jolanda Van Bilsen (The Netherlands)

A mixed methods investigation into a new Clinical Psychology service in Children’s Allergy Joanne Ridgley (United Kingdom)

Seasonal variations in adverse reactions during pollen subcutaneous immunotherapy in children Umit Sahiner (Turkey)

Preschool wheezing and asthma in children: Systematic review of guidelines and quality appraisal with the Agree II Instrument Marek Ruszczynski (Poland)

Clinical Immunology > Clinical Allergology > Dermatology > Pediatrics Thematic Poster Sessions (TPS)

TPS 21 Atopic dermatitis and miscellaneous Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 1 in e-Poster Area A (FIL)

Chairs Thilo Jakob (Germany) Edward Frank Knol (The Netherlands)

Therapeutic advantage of bacterially delivered toll-like receptor 8 MiRNA in atopic dermatitis Young Yoo (South Korea)

Dupilumab as treatment for severe recalcitrant atopic dermatitis - real life experience in an Austrian cohort Tamara Quint (Austria)

Safety and efficacy of cyclosporine a in the treatment of severe atopic eczema in children and adolescents (experience of one centre) Otília Petrovicová (Slovakia)

Predicting skin barrier dysfunction and atopic dermatitis in early infancy Eva Maria Rehbinder (Norway)

Epidemiological study of atopic dermatitis in Mexico Diana Andrea Herrera Sánchez (Mexico)

Prevalence and primary incidence of atopic dermatitis in armenia Anna Sargsyan (Armenia)

Impact on the quality of life of patients with atopic dermatitis in different cities of Argentina Maria Cecilia Cavallo (Argentina)

Atopic dermatitis and impact on HRQoL Maria Eugenia Alul (Argentina)

”I look disgusting” – a qualitative enquiry into the impact of atopic dermatitis on quality of life in adults Gurkiran Birdi (United Kingdom)

Fullerene C60 aqueous dispersions exhibits anti-inflammatory activity in murine model of chemical burn Evgeny Turetskiy (Russia)

Evaluation of the antioxidant defense of patients with atopic dermatitis Roseani da Silva Andrade (Brazil)

Eczema Herpeticum On A Tattoo Anca C Chiriac (Romania)

The 1196 C> T polymorphism of the TLR-4 gene and cytokine profiles in adults with extrinsic (exogenous) and intrinsic (endogenous) forms of atopic dermatitis Yuriy Bisyuk (Ukraine)

Capsaicin-induced atopic dermatitis-like symptoms were improved by suppression of NF-KB signal Sun-Ho Kee (South Korea)

Determinants of vitamin D deficiency in chilean children with atopic dermatitis Arturo Borzutzky (Chile)

Drug allergy > Dermatology > Clinical Immunology

Thematic Poster Sessions (TPS) TPS 22 Non-immediate hypersensitivity Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 2 in e-Poster Area A (FIL)

Chairs Cristobalina Mayorga (Spain) Robert Boyle (United Kingdom)

The role of immunoglobulin, plasmapheresis and corticotherapy in the treatment of stevens-johnsons syndrome / toxic epidérmic necrolysis Iolanda Alen Coutinho (Portugal)

Steven johnson syndrome to allopurinol: Case report Etleva Qirko Loloci (Albania)

Amoxicillin-induced toxic epidermal necrolysis with a fatal evolution Ana-Maria Moiceanu-Sovarel (Romania)

Seven-months retrospective study on drug hypersensitivity reaction with emphasis on severe cutaneous adverse reactions (SCARs) in our tertiary allergology clinic Ileana Maria Ghiordanescu (Romania)

A probable pediatric case of acute generalized exanthematous pustulosis due to metamizole Beatriz Moya Camacho (Spain)

Characterisation of an acute localised pustular drug reaction Emily N C Ryder (New Zealand)

Skin desquamation and onycholysis nonpigmenting fixed drug eruption caused by amoxicillin Beatriz Moya Camacho (Spain)

Delayed systemic hypersensitivity reaction due to mitomycin C Miriam Sobrino García (Spain)

Cutaneous reaction after intravesical instillation of mitomycin C Marta Bernaola (Spain)

Successful desensitization to anti-tuberculosis drugs in patients with delayed-type allergic reactions Derya Ünal (Turkey)

Kounis syndrome type II despite premedication. A case report Regina Maria Paulauskas Vasaitis (Spain)

Fixed drug eruption induced by meloxicam Talía María de Vicente Jiménez (Spain)

Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) to spiramycin with tolerance to other macrolides Nicola Giangrande (Italy)

Erythematous rash after treatment with amphotericin B Miriam Sobrino García (Spain)

Evaluation of diagnosis tests in patients with dress sindrome Marta Reguero-Capilla (Spain)

Allopurinol induced dress syndrome with renal involvement Denislava Nedeva (Bulgaria)

Lyell's syndrome in a female patient with multiple autoimmune disorders Erina Lazri (Albania)

Delayed hypersensitivity reactions to adalimumab in a patient with rheumatoid arthritis successfully treated with immunoglobulin Ji Hye Kim (South Korea)

Inflammatory Side Effect Of An Anti-Inflammatory Drug: Infliximab Related Leukocytoclastic Vasculitis Ceyda Tunakan Dalgiç (Turkey) ENT > Ocular Allergy > Pediatrics > Allied health and primary care

Thematic Poster Sessions (TPS)

TPS 23 Rhinitis: Cofactors and comorbidities Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 3 in e-Poster Area A (FIL)

Chairs Sanna Toppila-Salmi (Finland) Serge Doan (France)

How to identify allergic rhinitis from danish registries: A validation study Katja Biering Leth-Møller (Denmark)

Investigation of allergic rhinitis epidemics by baidu index in China Yujie Cao (China)

Ambrosia pollen count correlated with pediatric hay fever symptoms in Kyiv, Ukraine Victoria Rodinkova (Ukraine)

Does new sensitisation correlate with nasal symptoms in children with allergic rhinitis? Chae-Seo Rhee (South Korea)

Prevalence of allergic diseases in adolescents according to gender Cristine Secco Rosario (Brazil)

Self-assessed prevalence of allergic rhinitis among university students in Yerevan Zaruhi Gevorg Kalikyan (Armenia)

Evaluation of olfactory function in children with vernal keratoconjunctivitis Banu Bozkurt (Turkey)

Validation of EQUICK – an electronic tool in english for monitoring symptoms of vernal kerato-conjunctivitis Vibha Sharma (United Kingdom)

Tacrolimus 0.1% eye-drops in Vernal Kerato-Conjunctivitis refractory to cyclosporine: Our experience Chiara Ciurlo (Italy)

Impact of psychological traits on perceived severity of hay fever Mihaela Zidarn (Slovenia)

MP-AzeFlu improves quality of life of patients with allergic rhinitis Ludger Klimek (Germany)

The importance of patients’residence in the evaluation of inflammation in allergic rhinitis Nicolae Ovidiu Berghi (Romania)

Serum allergen-specific IgE in patients with rhynitis classified according ARIA Amelia Licari (Italy)

The nasal congestion reasons in topical nasal decongastants abuse patients Elena Radtsig (Russia)

The prevalence of high risk of obstructive sleep apnea in patients with allergic rhinitis Paraya Assanasen (Thailand)

Development and assessment of a novel nasal polyposis symptom diary Sean O’Quinn (United States)

Food allergy > Clinical Allergology > Pediatrics Thematic Poster Sessions (TPS)

TPS 24 Epidemiology of food allergy II Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 4 in e-Poster Area A (FIL)

Chairs Silvia Sanchez-Garcia (Spain) Ana Morête (Portugal)

Prevalence of food hypersensitivity in relation to IgE sensitisation among the general adult population in West Sweden Georgios Rentzos (Sweden)

Prevalence of pollen food allergy syndrome and accompanying factors in the eastern black sea region Adile Berna Dursun (Turkey)

Patterns of sensitization to food allergens among patients with atopic dermatitis from the Eastern Siberia of Russia Sergey Yurievich Tereshchenko (Russia)

Prevalence of self reported food allergy in adults at a federal university in Niteroi, Brazil Jose Laerte Boechat (Brazil)

Effects of folic acid supplement intake during pregnancy on food allergy onset in female children Masako Abe (Japan)

Investigation of culprit foods and symptomatic severity in korean adult food allergy: Single-center experience Sang chul Lee (North Korea)

Clinical manifestations and outcomes of allergic reaction to shellfish in adult and children: Data from the food allergy research & education (FARE) registry Mary Jane Marchisotto (United States)

The most precious milk Corina Marton (Romania)

Persistent and late onset milk allergy: A retrospective study Lucinda Kennard (United Kingdom)

General knowledge of food allergy and application of the FIC regulation in bakeries in the Epinal area, France Amelie Vaillant (France)

Food allergy sensitization by immunoCAP in Mexican allergic patients Lucy Tania Ruiz Segura (Mexico)

Sesame seed allergy – same food, different allergens? Cristiana Cancela Ferreira (Portugal)

Anaphylactic reaction to : A case series in a child and adult patient without prior risk factors Hasandeep Kular (Canada)

Poppy seed allergy in the Czech Republic Ludmila Dvorakova (Czech Republic)

The global incidence and prevalence of anaphylaxis in children in the general population: A systematic review Yichao Wang (China)

Food-induced anaphylaxis among infants and children up to 2 years of age Ewa Cichocka-Jarosz (Poland)

Peanut induced anaphylaxis in children and adolescents: Data from the European anaphylaxis registry Ioana Maris (Ireland) Asthma > ENT > Basic Immunology > Basic Allergology

Thematic Poster Sessions (TPS)

TPS 25 Impact and mechanism at the respiratory barrier Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 5 in e-Poster Area A (FIL)

Chairs Sven F Seys (Belgium) Tomás Chivato (Spain)

Long-term intranasal exposure to house dust mite allergen in mice without systemic sensitization leads airway remodeling Jeom Kyu Lee (South Korea)

Safety, tolerability, pharmacokinetics and pharmacodynamics of AUR101, An ROR?t inhibitor, in normal healthy volunteers Akhil Kumar (India)

Immunomodulatory effects of PON1 on airway inflammation and remodeling in bronchial asthma Sung-Dong Kim (South Korea)

The expression level of proinflammatory cytokines depending on the difference of microbiome among mites; dermatophagoides farinae, dermatophagoides pteronyssinus and tyrophagus putrescentiae JIN YOUNG LEE (South Korea)

Damage-associated molecular patterns molecules as a possible biomarker in allergic airway inflammation Jae Sung Nam (South Korea)

Effect of intermittent hypoxia from obstructive sleep apnea on respiratory allergic disease Seung Min In (South Korea)

Clinical manifestations and upper respiratory tract microflora composition in patients with primary immunodeficiency in samara region Natalia Begievna Migacheva (Russia)

Extracellular vesicle of adipose-derived stem cells: A role for allergic airway inflammation in asthmatic murine model Sue Jean Mun (South Korea)

Immune and endocrine parameters of infants with thymomegaly associated with acute obstructive bronchitis Lyudmila P Sizyakina (Russia)

Elevated levels of periostin, IL-13, and TGF-ß1 in the bronchoalveolar lavage fluid of patients with idiopathic eosinophilic pneumonia Shigeki Katoh (Japan)

Pharmacological analysis of T cell-induced bronchoconstriction in vitro and in vivo Akio Mori (Japan)

Development of experimental allergic asthma using pollen extract Olesya O. Koloskova (Russia)

Dermatology > Clinical Immunology > Basic Immunology > Pediatrics

Thematic Poster Sessions (TPS) TPS 26 Atopic Dermatitis: Clinical aspects Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 7 in e-Poster Area B (FIL)

Chairs Victoria Cardona (Spain) Stefanie Eyerich (Germany)

Effect of oral steroid treatment on alarmin expression of mast cells in the dermis of patients with moderate-to-severe atopic dermatitis Christiane Whetstone (Canada)

The effect of steroid treatment on eosinophil progenitors, eosinophils and basophils in the skin of patients with moderate-to-severe atopic dermatitis Emma Price (Canada)

Activated leukocyte cell adhesion molecule modulates Th2 immune response in atopic dermatitis Jung Yeon Hong (South Korea)

Impact of VOC emissions from pine wood on inflammatory skin disease Evelyn Schneider (Germany)

Infantile atopic dermatitis: Serum vitamin D, TARC and periostin levels and their relationship with disease phenotype and clinical severity Saliha Esenboga (Turkey)

Microbiological findings on skin specimens in patients with atopic eczema Besim Prnjavorac (Bosnia and Herzegovina)

Epidermal lipid and skin microbiome composition are altered in Korean patients with atopic dermatitis Jihyun Kim (South Korea)

Maternal and paternal atopy and risk of eczema in early infancy: A sex-stratified analysis of a large cohort Kim Magnus Advocaat Sandberg Endre (Norway)

Sensitization to cockroach tropomyosin among patients with atopic dermatitis Sarah Sella Langer (Brazil)

Alterations in skin physiology are associated with disease severity in chilean patients with atopic dermatitis Arturo Borzutzky (Chile)

Type 2 innate lymphoid cells (ILC2s) are reduced in lesional skin biopsies from subjects with atopic dermatitis (AD) following treatment with oral corticosteroids Sakktee S Krisna (Canada)

Serum level of IL-19 and pro-inflammatory cytokines (IL-17A, IL-4 And IL-1ß) in children with atopic dermatitis - the role and association with disease severity Karolina Dumycz (Poland)

Comparative analysis of fragrance haptens in emollients available in Poland and Spain Monika Sojewska (Poland)

The use of probiotics in topical treatment of atopic dermatitis – a systematic review Dominika Ambrozej (Poland)

Dupilumab is very effective in a large cohort of difficult-to-treat adult atopic dermatitis patients: First clinical and biomarker results from the Bioday registry Lieneke Fm Ariëns (The Netherlands)

Dupilumab in adolescents with moderate-to-severe atopic dermatitis and a history of allergic rhinitis: Subgroup analysis from a randomized phase 3 trial Lawrence Sher (United States)

Efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis with and without comorbid asthma: Subgroup analysis from a 16-week randomized phase 3 trial Mark Boguniewicz (United States)

Microbiome stability and skin physiology in atopic eczema patients and healthy controls upon application of emollients with different PH Claudia Hülpüsch (Germany)

Establishment of facial atopic dermatitis with scratching (FADS) mice by deleting Ikk2 in dermal fibroblasts Satoshi Nunomura (Japan)

Cytokines and adipokines in serum of psoriasis patients with varying body mass index R Khanferyan (Russia)

Food allergy > Allied health and primary care > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 27 Management of food allergy Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 8 in e-Poster Area B (FIL)

Chairs Ana Célia Costa (Portugal) Nicolette Wilma de Jong (The Netherlands)

Probiotic peanut oral immunotherapy (PPOIT) is effective at inducing 8-week sustained unresponsiveness after 18 months of treatment Mimi L. K. Tang (Australia)

The Literature Discusses The Effect Of Probiotics On The Course Of Allergic Diseases Through The Modulation Of The Immune Response. Inna A. Larkova (Russia)

Combination of pre- and probiotics as a new perspective in the treatment of José Luis Justicia (Spain)

Comparison of different dietary instruction methods for children with suspected or mild hen’s egg allergy Katsumasa Kitamura (Japan)

Assessment of potential cross-reactivity with tree nuts, peanut and seeds in Japanese children with macadamia nut allergy Koichi Yoshida (Japan)

Wheat-dependent exercise-induced anaphylaxis: Clinical presentations and management in a UK adult cohort Wei Chern Gavin Fong (United Kingdom)

Knowledge and proficiency of dietitians regarding food allergy in Lebanon Dominique Dano (Lebanon)

The importance of interaction in nutritional counselling Henning Haab (Germany)

Welcoming Patients With Food Allergy: What Is The Preparation Of Schools And Restaurants? Inês Pádua (Portugal)

Intervention for management and control of food allergens in school canteens in Hortaleza district 2014-2017 in Madrid, Spain Martha Cabrera (Spain)

Presenting features and management of infant anaphylaxis Katherine Anagnostou (United Kingdom)

Factors predicting anaphylaxis in children with tree nut allergies Bulent Sekerel (Turkey)

Life: In a nut free shell Amena Warner (United Kingdom) “People don’t know how severe some of them can be.”: An exploration of beliefs and attitudes in adolescents with food allergy Kristina Newman (United Kingdom)

Health related quality of life among adolescents with food hypersensitivity Marina Jonsson (Sweden)

Qualitative exploration of the adult’s perspective of undergoing a food challenge test Melina Makatsori (United Kingdom)

Post traumatic stress disorder (PTSD) in parents of pediatric anaphylaxis patients; using BDI-II, BAI, And IES-R Gwang-Cheon Jang (South Korea)

Nine-year survey of anaphylaxis in an allergy department Ângela Gaspar (Portugal)

Understanding the health and economic benefits of commercial peanut immunotherapy products: A cost-effectiveness analysis Matthew Greenhawt (United States)

Food allergy > Basic Allergology

Thematic Poster Sessions (TPS)

TPS 28 Mechanisms of food allergy Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 9 in e-Poster Area B (FIL)

Chairs Barbara Bohle (Austria) Sonsoles Infante (Spain)

Does Foxp3 methylation affect the development of food allergy in children? Maria Kostara (Greece)

Investigation of increased prevalence of IgE specific for galactose alpha-1,3-galactose in patients with coronary artery disease Thomas A Platts-Mills (United States)

Novel insights into the allergenic relationship between red meat and bovine milk Marija Branimir Perusko (Serbia)

Household Exposure To Food Allergens: A Risk For Sensitization? Izabel Alvares (United Kingdom)

The role of chitinase 3-like–1 in the regulation of food allergy EUN GYUL KIM (South Korea)

Measurement of naturally occurring variation in allergens and isoforms of peanut Philip Johnson (United Kingdom)

Metabolomic analysis of an allergic enteritis murine model by GC-MS Tomás Clive Barker Tejeda (Spain)

Germ-free mice do not develop food allergy despite high levels of sensitization due to mast cells impaired functionality and gut homing Petra Hermanova (Czech Republic)

Characterization of circulating dendritic cells in peanut allergy patients Luis Venegas (Chile)

Potential role of CD73 in basophil non-reactivity Theodore Kim (United States)

Allergen-specific profiling of sera from patients with peanut allergy Marta Paolucci (Switzerland)

Epitope-specific antibody profiling in food allergy using novel multiplex immunoassay: Design and validation Maria Suprun (United States)

Effect of housing conditions and route of administration in inducing peanut allergy in mice Kunal Pratap (Australia)

Investigation of the sensitization potential of sunflower seed proteins in a mouse model Jihana Achour (France)

Hydrolyzed faba bean proteins prevent the development of allergic reaction in a mouse model of cow’s milk allergy Carine DELAYRE-ORTHEZ (France)

Method for quantitation of food allergens in serum by basophil histamine release Per Stahl Skov (Denmark)

A jurkat based NF?B-EGFP INKT reporter cell line to evaluate the interaction of food-derived lipids with INKT cell receptors Piotr Humeniuk (Austria)

Interaction of mustard Seed 2s albumin allergen Sin a 1 with intestinal epithelial cells as a model in allergy development Cristina Bueno-Díaz (Spain)

Expression of prostaglandin E2 receptors in food anaphylaxis Rosa Muñoz-Cano (Spain)

Environmental and occupational allergy

Thematic Poster Sessions (TPS)

TPS 29 Allergens, pollutants and other environmental factors Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 10 in e-Poster Area B (FIL)

Chairs Jeroen Titus Buters (Germany) Gennaro D'Amato (Italy)

Particulate matters downregulate the expression of structural components in normal human epidermal keratinocytes Sun Hwa Hong (South Korea)

The effect of mechanical air purifier for improving allergic symptom scores of allergic children Jae-Won Oh (South Korea)

Association between prenatal exposure to PM2.5 and atopic eczema in Asian school-age children Hsin-Yi Huang (Taiwan)

Prenatal exposure to PM10 levels and development of childhood eczema Shun-Yu Tsai (Taiwan)

The effects of particulate matter exposure on allergic rhinitis-related hospital visits in the Republic of Korea Dae Hyun Lim (South Korea)

Urban particulate matter induces nasal epithelial barrier dysfunction by targeting tight junctions in human nasal epithelial cells SooKyoung Park (South Korea) Air pollution is a risk factor for noncomunicable diseases in a small Brazilian city? Marilyn Urrutia Pereira (Brazil)

Efficacy of behavioural interventions for smoking cessation during pregnancy Natalia Astafieva (Russia)

The changes of sensitization rate to inhalant allergens over the last 10 years in Korea Jung Yeon Shim (South Korea)

The inner-city asthma in Zagreb: 2018 versus 2004 Iva Topalusic (Croatia)

Are new types of smoking alternatives better than conventional tobacco for the prevention of asthma in adolescence? Min-Suk Yang (South Korea)

Progress in automated airborne pollen monitoring with the BAA500 Stefan Schaefer (Germany)

Automated dander dispersion in a naturalistic exposure chamber Laura Haya (Canada)

Comparison of methods for cat dander aerosolization Laura Haya (Canada)

Dermatology > Pediatrics > Clinical Immunology > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 30 Urticaria and angioedema II Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 11 in e-Poster Area B (FIL)

Chairs Luis Miguel Borrego (Portugal) Tabi Leslie (United Kingdom)

Chronic spontaneous urticaria (CSU) associated with chronic inducible urticaria (CIndU): Efficacy of omalizumab Solange Oliveira Rodrigues Valle (Brazil)

How to discontinue omalizumab in chronic spontaneous urticaria? Murat Türk (Turkey)

Low-responsiveness of basophils via FceRI reflects disease activity and duration of disease in chronic spontaneous urticaria Yoshiko Oda (Japan)

Basophil phenotypic and functional profiles of 31 patients with chronic spontaneous urticaria Claude LAMBERT (France)

Our data on the link between chronic urticaria and helicobacter pylori Zaruhi Gevorg Kalikyan (Armenia)

Worsening of chronic spontaneous urticaria after intake of hot pepper Murat Türk (Turkey)

CSU treatment with omalizumab in a pediatric patient Cristine Secco Rosario (Brazil)

Cold Urticaria In Children Raisa Yakovlevna Meshkova (Russia)

Cold urticaria in a child with familial mediterranean fever Emine Vezir (Turkey)

Clinical experience of a chronic urticaria referral university center Eduardo Costa (Brazil)

Differential diagnostics of chronic urticaria and urticarial vasculitis by hyperspectral imaging Inna Vladimirovna Danilycheva (Russia)

Clinical profile of patients with spontaneous chronic urticaria in a federal university hospital in Brazil Daniella Batalha Moore (Brazil)

Omalizumab treatment of recalcitrant delayed pressure urticaria Aleksandra Bergant Suhodolcan (Slovenia)

Management of histaminergic disorders: The contribution of the immunoallergist illustrated through 5 cases Jeremy CORRIGER (France)

Cases of contact dermatitis mimicking angioedema Emine Vezir (Turkey)

Urticaria-angioedema paraneoplastic syndrome associated with renal cells carcinoma Ana Rodolfo (Portugal)

A very unexpected cause of chronic urticaria Míriam Araújo (Portugal)

Allergy profile in patients with urticaria in Reunion Island Bashir Omarjee (Reunion)

Urticaria and urticarial vasculitis: 2 entities, the same trigger Cristina Lara Valente (Portugal)

Environmental and occupational allergy

Thematic Poster Sessions (TPS)

TPS 31 Airborne allergens Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 13 in e-Poster Area C (FIL)

Chairs Gerard Koppelman (The Netherlands) Ana Margarida Pereira (Portugal)

Grass pollen potency in ambient aerosol; grass pollen counts; seasonal allergic rhinitis; meteorological factors and pollutants in Madrid, Spain, during 2009 and 2010 Martha Cabrera (Spain)

Patterns of google trend terms related to reporting rhinitis and the ragweed pollen season in Ukraine Igor Kaidashev (Ukraine)

Olea pollen count in a changing climate, 38 years of observation Javier Subiza (Spain)

Validation of an in-house monoclonal antibody-based ELISA method for the quantification of Sal k 1 major allergen from salsola kali Raquel Moya (Spain)

Cypress pollen allergy in Georgia Tamar Abramidze (Georgia)

Can airborne populus seeds be a potential cause of pollen allergies? An aerobiological study Helena Ribeiro (Portugal) An in vitro exposure chamber for whole pollen at the air-liquid-interface Joana Candeias (Germany)

Salsola kali sensitization and cross-reactivity with olea europea in patients with pollinosis from Alcázar de San Juan, Ciudad-Real, Spain Ana Burgos-Montero (Spain)

The influence of meteorological parameters on intradiurnal patterns of airborne pollen in Helmond, the Netherlands Mieke M.j.f. Koenders (The Netherlands)

Changes in pollen and spore levels during rain and hail Victoria Rodinkova (Ukraine)

Epidemiological study of allergic rhinitis for hospital workers in University of Fukui between 2006 and 2016 Masafumi Sakashita (Japan)

The study for revision of threshold levels for pollen allergy risk grade in Korea Jae-Won Oh (South Korea)

Cross-blocking activity of specific antibodies induced by SLIT with RBet V 1 João Grilo (Austria)

Impact of non-allergenic components of ragweed pollen on IgE synthesis to allergenic components R Khanferyan (Russia)

Specificity of mold sensitization among patients with respiratory disease in different settlements in Bulgaria Diana Hristova (Bulgaria)

A numerical evaluation of cat dander levels by safranin-O staining Suzanne Kelly (Canada)

Feasibility study: Comparison of source and exposure indexes of allergenic pollen trees in lyon's green spaces with data from the pollen diary (PHD) Charlotte Sindt (France)

Allergy diagnosis and systems medicine > Clinical Allergology > ENT > Precision Medicine

Thematic Poster Sessions (TPS)

TPS 32 New laboratory tests and biomarker candidates Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 14 in e-Poster Area C (FIL)

Chairs Kornel Golebski (The Netherlands) Jörg Kleine-Tebbe (Germany)

Demonstration of immunoassay performance of the noveostm specific IgE assay with allergens: D001 (D. Pteronyssinus), E001 (Cat Dander), G006 (Timothy Grass), F013 (Peanut), and W006 () Ailan Wang (United States)

Evaluation of biotin interference in specific IgE assays processed on the NOVEOS™ immunoanalyzer, Phadia™ 1000 system, and IMMULITE® 2000 instrument Edsel Sinson (United States)

Establishment of an ELISA for quantification of allergen-specific IgE: Comparison with quantitative immunoCAP and chip-based immunoCAP ISAC measurements Antonina Karsonova (Russia)

The first comparison ot two multiparameter methods to measure allergen specific IgE among the polish group of kids suffering from allergy Emilia Majsiak (Poland) A comprehensive comparison between ISAC and ALEX multiplex test systems Theo Roovers (The Netherlands)

Molecular profile of patients with allergopathology in different regions of ukraine by the results of ALEX investigation Serhii Dmitrievich Yuriev (Ukraine)

Some trends in the comparative analysis of the results of ALEX in children with allergic diseases Hanna Kasianenko (Ukraine)

Application of biochip microfluidic technology to detect serum allergen-specific immunoglobulin E (SIgE) Zhifeng Huang (China)

Does specific IgE to grass pollen allergens / total IgE ratio better reflect the presence of clinically relevant allergy than specific IgE itself? Martin Liska (Czech Republic)

Cross-reactive carbohydrate determinant (CCD) inhibition test can help identify false positive for plant allergen-SIgE caused by CCD Luo Wenting (China)

Identification of unique grass species peptides, in a thirteen grass species aqueous extract sample by LC-MS/MS Matthew D. Heath (United Kingdom)

Characterization of a panel of profilin allergens for a structure-based IgE-epitope mapping Nina Alice Gottstein (Austria)

Investigations of the major horse allergen Equ C 1 derived from the presumably hypoallergenic curly horse Bente Janssen-Weets (Germany)

Identification and characterization of a novel allergen, 30 KDa lipoprotein, from silkworm pupa Jang Seok Woo (South Korea)

Betula verrucosa may be taken as a marker allergen for Tx5 tree mix Romy Mariette Marie Joseph Gadisseur (Belgium)

Phleum pratense may be taken as a marker allergen for Gx3 grass mix Romy Mariette Marie Joseph Gadisseur (Belgium)

Analytical performance of a new chemiluminescent singleplex IgE assay Ekaterina Potapova (Germany)

Method development for allergen capture from allergenic sources using human IgE-antibodies Julia Klueber (Luxembourg)

Periostin forms the complex with IgA in human serum Junya Ono (Japan)

Allergen immunotherapy > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 33 Immunotherapy III: Clinical focus Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 15 in e-Poster Area C (FIL)

Chairs Roy Gerth van Wijk (The Netherlands) Umit Sahiner (Turkey)

Sublingual immunotherapy in patients with perennial allergic rhinitis and SCUAD Phenotype Rajica Stošovic (Serbia) Immunological assessment of different allergen-specific immunotherapy types in children with hay fever Saule Zhumambayeva (Kazakhstan)

Objectivation of the deviation of the natural course of patients with asthma and rhinitis in specific allergen immunotherapy with dermatophagoides and blomia Susana Uribe (Colombia)

An Accelerated Build-Up Phase Increases The Adherence To Allergen Subcutaneous Immunotherapy. A Retrospective Study stefania colantuono (Italy)

Early efficacy of double-species mites allergen immunotherapy in allergic rhinitis Xiaoqing Liu (China)

Effectiveness and safety of allergen-specific immunotherapy in allergic rhinitis and asthma patients: Experience of a Portuguese immunoallergology department Sara Almeida Heleno (Portugal)

The effects of sublingual immunotherapy in our department Yasuhiro Suzuki (Japan)

Comparative analysis of sublingual immunotherapy medicines for adherence and clinical outcomes Kyu-Sup Cho (South Korea)

Clinical and immunological changes after 1-year treatment with a tyrosine-adsorbed mite allergoid: D. Pteronyssinus 50% + D. Farinae 50% Federico De La Roca Pinzon (Spain)

Effectiveness of sublingual allergen-specific immunotherapy (ASIT) in patients with adverse gastrointestinal reactions in the course of the therapy Marina Peredelskaya (Russia)

Parallel combination of AITs in a teen-age boy Magdalena Herknerova (Czech Republic)

Sublingual immunotherapy with 5-grass pollen extract tablets: Can immunization to cross-reactive non-specific lipid-transfer proteins (NsLTPs) occur? Fabiana Furci (Italy)

ENT > Allergy diagnosis and systems medicine > Clinical Allergology > Clinical Immunology

Thematic Poster Sessions (TPS)

TPS 34 In vivo and in vitro tests for allergy diagnosis Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 16 in e-Poster Area C (FIL)

Chairs Stephen Till (United Kingdom) Isabel Janet Skypala (United Kingdom)

Could multiple allergen simultaneous test detect the additional allergen sensitization and improve allergic rhinoconjunctivitis diagnosis? Ju Hee Kim (South Korea)

Outdated allergen extracts have equivalent potency and bioavailability as unexpired extracts for the detection of allergen sensitization by skin testing Yoram Faitelson (Israel)

Evaluation of autologous serum skin test positivity and autoantibodies status in patients with chronic spontaneous urticaria (CSU) Grazielly De Fátima Pereira (Brazil)

An nasal secretion preparation method: Paving an effective way for noninvasive local IgE measurement Feng Lan (China)

IgE testing in nasal secretions Sveva Castelli (Italy)

The correlation between nasal eosinophil count and percentage in children with allergic rhinitis Kyou Hyun Yoon (South Korea)

Local specific immunoglobulin E in rhinitis and local nasal response in Russian population Irina Nickolaevna Grigorieva (Russia)

Results of nasal provocation test, change in patients with systemic or local allergic rhinits, according to visual analog scale vs rhinometry Ana Maria Calle (Colombia)

Prediction of positive nasal provocation test according to molecular components of furry animals Andrés Felipe Sánchez Caraballo (Colombia)

Phenotypes diagnosis of allergic rhinitis using nasal provocation test Natalia Aliakhnovich (Belarus)

Different phenotypes of the sensitization in allergic respiratory patients Amelia Licari (Italy)

Toward identifying biomarkers of efficacy of allergen immunotherapy tina skjold (Denmark)

Elucidating the role of platelet functions in the development of severe allergic reactions Leticia Mera-Berriatua (Spain)

Multiallergic patient undergoing cardiac surgery. Safety of an in vitro testing strategy Amelia Licari (Italy)

Systemic mediators are associated to oral mucosa remodelling in severe respiratory allergy Cristina Gomez-Casado (Spain)

Diseases related to serum total tryptase measurements and diagnostic value Jóni Costa Carvalho (Portugal)

ALLERGY TO LIVE FISH BAIT Mónica Sánchez Pérez (Spain)

ENT > Pediatrics > Clinical Allergology > Allergy diagnosis and systems medicine

Thematic Poster Sessions (TPS)

TPS 35 Allergic rhinitis and atopy in children Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 17 in e-Poster Area C (FIL)

Chairs Valerie Hox (Belgium) Brecht Steelant (Belgium)

High prevalence of nasal allergy development in infants with atopic dermatitis and/or food allergy: A prospective cohort study Naofumi Suzuki (Japan)

The deficiency of vitamin D3 is associated with allergic rhinitis and sleep problem Man Yong Han (South Korea)

Childhood atopic status in relation to rhinitis in adolescence and early adulthood Tsung-Chieh Yao (Taiwan) Nasal provocation can be useful for diagnosing children with local allergic rhinitis S. Tolga Yavuz (Germany)

Olfactory dysfunction in children with moderate to severe allergic rhinitis Ryohei Suzuki (Japan)

Local atopy in childhood adenotonsillar hypertrophy Keun-Ik Yi (South Korea)

A polycentric, randomized, double blind, parallel-group, placebo-controlled study on a nutraceutical as add-on treatment in children with allergic rhinoconjunctivitis: Phase I during active treatment Amelia Licari (Italy)

A polycentric, randomized, parallel-group, study on a multicomponent nutraceutical, as preventive treatment in children with allergic rhinoconjunctivitis: Phase II Amelia Licari (Italy)

Total antioxidant status (TAS), pulmonary function and nutritional status in children with allergic rhinitis. A six-month follow-up study Eliza Wasilewska (Poland)

Assessment of leukotriene E4 as a marker of inflammation in allergic rhinitis children with antihistamine/leukotriene receptor antagonist and leukotriene receptor antagonist Yong Mean Park (South Korea)

Dog ownership and farm exposure during pregnancy are associated with increased interferon-gamma production by cord blood mononuclear cells Sergey Yurievich Tereshchenko (Russia)

Allergen immunotherapy

Thematic Poster Sessions (TPS)

TPS 36 AIT: Mechanisms and allergens Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 19 in e-Poster Area D (FIL)

Chairs Stephen R Durham (United Kingdom) Mark Larché (Canada)

Unbiased mass cytometry analysis method applied to high-dimensional single cell phenotyping deciphers tolerance induction in a model of allergen immunotherapy Guillem Montamat (Luxembourg)

Assessment of pre-clinical blocking activity of a hypoallergenic birch pollen vaccine candidate Lorenz Aglas (Austria)

Sensitization pattern of the new HDM major allergen Der P 23 in Japanese HDM hdm allergic rhinitis patients Katsuyo Ohashi-Doi (Japan)

Epicutaneous immunotherapy (EPIT®) protects from anaphylaxis in cashew nut-sensitized mouse model Benjamin Pelletier (France)

Expression of MicroRNAs during venom immunotherapy does not correlate with basophil activation test Krzysztof Specjalski (Poland)

An adjuvant systems approach to develop vaccines against challenging diseases: Dioleoyl phosphatidylserine (DOPS) confers enhanced protection against malaria for VLP-TRAP based vaccines Matthew D. Heath (United Kingdom)

In vivo and in vitro efficacy of a modified aluminum hydroxide-adsorbed extract of house dust mite subcutaneous immunotherapy in sicilian allergic patients Carina Gabriela Uasuf (Italy) Biodegradable transdermal microneedle immunotherapy can ameliorate airway inflammation in murine asthma model Kyung Hee Park (South Korea)

Detection of Mollicute species (Mycoplasma) in House Dust Mites Kees Van Der Graaf (The Netherlands)

Analysis of the effect of vaccination against pneumococcal infection on the course of comorbid pathology in patients with chronic obstructive pulmonary disease and chronic heart failure Vladimir Antonov (Russia)

Development of a total antigenicity IgG ELISA for the quality control of a mixed grass allergoid drug product Sviatlana Starchenka (United Kingdom)

Asthma > Pediatrics

Thematic Poster Sessions (TPS)

TPS 37 Asthma classification, scoring and treatment in children Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 20 in e-Poster Area D (FIL)

Chairs Matteo Bonini (Italy) Apostolos Bossios (Sweden)

Prevalence of asthma, respiratory symptoms and allergic diseases in children aged 13-14 in Katowice (Poland) – results of a cross sectional study Grzegorz Marek Brozek (Poland)

L-ficolin plasma concentration and FCN2 gene Rs17549193 And Rs7851696 polymorphisms in asthmatics children Sergey Yurievich Tereshchenko (Russia)

Asthma control assessment in children: Consistency of gina criteria asthma control test and asthma control questionnaire Anna Bodajko-Grochowska (Poland)

Assessment of the control of asthma and allergic rhinitis in children at a level II hospital Maria Cristina Granado (Portugal)

Allergic and non-allergic asthma across an urban-rural gradient Joshua A Lawson (Canada)

Clinical features of the bronchial asthma onset in children Oleksandr Katilov (Ukraine)

Asthma symptom control – patient’s versus physician’s perspective Inês Gonçalves Nunes (Portugal)

Role of vocal cord dysfunction in pediatric uncontrolled asthma Oleksandr Katilov (Ukraine)

Follow-up of patients with bronchial asthma after discontinuation of omalizumab Elena Vishneva (Russia)

Unexpected death in 10-yo boy with uncontrolled asthma and mega obesity – case report Eliza Wasilewska (Poland)

Change of quality of life by strengthening the daily life education and instruction of medicine and inhalation about asthmatic children Tomio Kondo (Japan) Drug allergy > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 38 Anaphylaxis and NSAID hypersensitivity Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 21 in e-Poster Area D (FIL)

Chairs Luciana Kase Tanno (Brazil) Martin Wagenmann (Germany)

Anaphylaxis due to a topic application of an insect repellent solution with detected hypersensitivity to N,N-Diethyl-3—methylbenzamide (DEET) Nicola Giangrande (Italy)

Association between severity of anaphylaxis and coexistence of respiratory diseases: A systematic review and meta-analysis of observational studies Sabela Pérez Codesido (Spain)

The diagnostic challenge of anaphylaxis in pediatric age Joana Gouveia (Portugal)

Formaldehyde IgE sensitization in Slovenian patients Urska Bidovec-Stojkovic (Slovenia)

Propionic hypersensitivity and atopy: Relationship between severity and airbone sensitization Ignacio García Núñez (Spain)

Promethazine anaphylaxis: A case report Stephanie Ching Ching YUNG (Hong Kong SAR)

A true anaphylactic reaction from local anesthetics Mehmet Avni Hoxha (Albania)

Anaphylaxis To Oral Administration Of A PEG Laxative Product Confirmed With Oral Challenge Maria Pasali (Greece)

Intraoperative anaphylaxis related to aprotinin after local application of fibrin sealant probably caused by an IgE-independent mechanism: A case report Tatsuo Horiuchi (Japan)

A case of acetyl salicylic acid (ASA) induced asthma attack presented for first time after wine-asa mixture consumption in a young man with previous history of ASA anaphylaxis Eralda Lekli (Albania)

Outcomes of patients undergoing nasal aspirin desensitisation for aspirin exacerbated respiratory disease at lancashire teaching hospitals, a tertiary adult allergy centre in the UK Ariharan Anantharachagan (United Kingdom)

CYSLTR2 genetic variants in nonsteroidal anti-inflammatory drug-induced urticaria/angioedema Jose Cornejo-García (Spain)

Nonsteroidal anti-inflammatory drug hypersensitivity in patients with clonal mast cell disorders – an exaggerated risk? Theo Gülen (Sweden)

A single NSAID-induced anaphylaxis to diclofenac, confirmed by skin testing Jaechun Lee (South Korea)

Selective-allergic reaction to heteroaryl-acetic acid derivates Leonor Esteves Caldeira (Portugal)

Allergy to a NSAID arylpropionic acid derived and tolerance to other NSAID aril-propionic Marta Reguero-Capilla (Spain)

Risk factors for developing positive lysine-aspirin nasal challenges in non-steroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease Inmaculada Doña Diaz (Spain)

Is etoricoxib a safe long term alternative in patients with NSAIDs hypersensivity reactions? Ana Margarida Mesquita (Portugal)

Nimesulide tolerance assessment in patients with non-selective non-steroidal anti-inflammatory drugs hypersensitivity Luis Felipe Chiaverini Ensina (Brazil)

Allergen immunotherapy

Thematic Poster Sessions (TPS)

TPS 39 Immunotherapy II: Clinical focus Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 22 in e-Poster Area D (FIL)

Chairs Adam M Chaker (Germany) Asli Gelincik (Turkey)

Effectiveness and safety of a modified Dermatophagoides Pteronyssinus allergoid, associated with microcrystalline tyrosine, in adult patients with allergic rhinitis, with or without asthma José Luis Justicia (Spain)

Results of immunotherapy with a polymerized extract associated with microcrystalline tyrosine, in patients with allergic asthma caused by the house dust mite dermatophagoides José Luis Justicia (Spain)

Improved quality of sleep in allergic rhinitis patients treated with house dust mite SLIT-tablet Henrik Jacobi (Denmark)

Long-term effect of aeroallergens sublingual immunotherapy in allergic rhinitis and asthma patients Carla Irani (Lebanon)

Long-term clinical effectiveness of sublingual immunotherapy in allergic rhinitis Plamena Ivanova Novakova (Bulgaria)

Evaluation of the long-term effect of allergen immunotherapy in local allergic rhinitis patients Carmen Rondon (Spain)

Safety and utility of rush immunotherapy with aqueous allergen extracts for the treatment of respiratory allergies Ji-Ho Lee (South Korea)

Peanut content of chocolate coated peanut candies present a higher variability when compared to conventional Alexandra Langlois (Canada)

Cow’s milk oral immunotherapy – characterization of our population Ana Palhinha (Portugal)

Safety of ultra-rush schedule of subcutaneous allergen immunotherapy with house dust mite extract conducted for 8 hours in an outpatient clinic in patients with allergic rhinitis Dong-Ho Nahm (South Korea)

Health and satisfaction results reported by patients, after a treatment based on a modified dermatophagoides pteronyssinus extract associated with microcrystalline tyrosine (MCT) José Luis Justicia (Spain) The health and economic impact of allergen therapy in patients with allergic rhinoconjunctivitis: Real-word evidence from the Czech Republic Tomáš Doležal (Czech Republic)

Allergic Bronchial Asthma Treated With House Dust Mite (HDM) Sublingual Immunotherapy Tablet (SLIT) : Clinical Profile Of Patients From Bengaluru Allergy Centr, India. Puneet Nagendra Komarla (India)

Classification and management of gastrointestinal symptoms during omalizumab-enabled oral immunotherapy Pauline AZZANO (France)

Grass pollen sublingual immunotherapy – experience in a UK children’s hospital Dinkar Bakshi (United Kingdom)

Thematic Poster Sessions (TPS)

TPS 40 Immunotherapy I: Clinical focus Monday, 3 June 2019

12:15-13:45 hrs Room e-Poster station 23 in e-Poster Area D (FIL)

Chairs Peter Socrates Creticos (United States) Marek Jutel (Poland)

No correlation between conjunctival provocation test and immune globulins in a positive phase II allergen immunotherapy study with subcutaneously administered tyrosine adsorbed modified grass allergen Pieter-Jan De Kam (United Kingdom)

Patient’s characteristics safety and use of allergy immunotherapy 12 SQ HDM SLIT-tablet in real-life clinical practice in adult patients with house dust mite allergy in france – an interim analysis Antoine Chartier (France)

Real-life adherence of subcutaneous (SCIT) and sublingual (SLIT) AIT: A retrospective, long-term cohort analysis in germany Christian Vogelberg (Germany)

Impact of subcutaneous house dust mite (HDM) allergoid AIT on HDM-triggered allergic rhinitis and/or asthma: A retrospective real-life, long-term cohort analysis in germany Marek Jutel (Poland)

SQ house dust mite sublingual immunotherapy-tablet demonstrated clinically relevant efficacy in Japanese children with allergic rhinitis Simon Andrew Lawton (Denmark)

Oral and sublingual immunotherapy: A systematic review of clinicaltrials.Gov records Eimar Yadir Quintero Tapias (Colombia)

Safety of subcutaneous immunotherapy in patients with asthma- reduced FEV1 as a predictor of systemic adverse events Piotr Lacwik (Poland)

Post-marketing survey on the safety and efficacy of the sq house dust mite (HDM) sublingual immunotherapy-tablet in Japanese patients with hdm-induced allergic rhinitis (interim analysis 2016 - 2018) Yuriko Maekawa (Japan)

Monitoring immune response and patient attitudes during sublingual immunotherapy in patients with respiratory allergic disease (RAD) Leif Bjermer (Sweden)

Is it possible to improve the efficiency of allergen-specific immunotherapy in children with seasonal allergic rhinoconjunctivitis? Inna A. Larkova (Russia) Rapid dose escalation with monomeric tree pollen allergoid drops is well tolerated in patients with allergic rhinoconjunctivitis and point towards clinical effects Esther Raskopf (Germany)

Strong dose-response on immunoglobulin markers during a phase II allergen immunotherapy study with subcutaneously administered tyrosine adsorbed modified grass allergen + MPL Pieter-Jan De Kam (United Kingdom)

Results of scit with a polymerised extract, associated with microcrystalline tyrosine, in allergic patients to dermatophagoides Spp. According to their sensitization profile to Der p1 and Der p2 José Luis Justicia (Spain)

Trial design for safety evaluation of an accelerated dose escalation schedule with one strength of a 6-grasses pollen allergoid in children and adolescents Matthias V. Kopp (Germany)

A retrospective study on the effects of subcutaneous immunotherapy using house dust mites in pediatric patients with allergic rhinitis Tsuzuki Yasunobu (Japan)

Early efficacy of HDM allergen immunotherapy in patients with allergic rhinitis Xiaoqing Liu (China)

Allergen immunotheraphy (AIT) with both perennial allergens show better control of AR than regular pharmacotheraphy and AIT with HDMs is more effective than parietaria in the treatment of asthma Derya Ünal (Turkey)

Shortened updosing with subcutaneous allergy immunotherapy: Results from a safety and tolerability trial Eike Wüstenberg (Germany)

Allergen immunotherapy > Clinical Allergology > Basic Allergology > Allergy diagnosis and systems medicine

Patent Abstract Session (PAS)

PAS The nuts and bolts of patenting: Make your first step Monday, 3 June 2019

12:20-13:35 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Simon Blank (Germany) Ulrich Matthias Zissler (Germany)

The needleless device for intralimphatic allergy immunotherapy Giovanni Maria Traina (Italy)

Highly nitrated food proteins: Induction of an allergen-specific modulatory immune response via the oral route associated with allergy prevention Eva Untersmayr (Austria)

Development of recombinant allergen based immuno-diagnostic platform for allergic disorders – house dust mite model Puneet Nagendra Komarla (India)

The electronic skin prick test Giovanni Maria Traina (Italy)

Optical device for the automatic measurement of the skin prick test Javier Marrugo (Colombia)

Agonist of NLR receptors in the complex therapy of oncological diseases Svetlana Guryanova (Russia) Company Sponsored Symposia (CSS)

CSS 6 Monday, 3 June 2019

12:20-13:40 hrs Room Hall 4 (Altice Arena)

Business Meetings (BM)

BM 10 Working Group Bilologicals - Open to all attendees Monday, 3 June 2019

12:25-13:35 hrs Room Hall 5 (Altice Arena)

Introductory lecture: Biologicals in children in allergic diseases: When to start, when to stop and financial considerations Antonio Nieto Garcia (Spain)

Business Meetings (BM)

BM 11 Interest Group Allied Health & Primary Care - Open to all attendees Monday, 3 June 2019

12:25-13:35 hrs Room Hall 9 (FIL)

Introductory lecture: Future integrated care in allergy: The comprehensive care concept in allergy Torsten Zuberbier (Germany)

Business Meetings (BM)

BM 12 Working Group Insect Venom Hypersensitivity - Open to all attendees Monday, 3 June 2019

12:25-13:35 hrs Room Hall 10 (FIL)

Introductory lecture: Antihypertensive drugs in insect venom allergy: Final results of the EADOAS multicenter study Lisa Arzt-Gradwohl (Austria)

Business Meetings (BM)

BM 9 Working Group Immunodeficiencies - Open to all attendees Monday, 3 June 2019

12:25-13:35 hrs Room Hall 3 (Altice Arena)

Introductory lecture: Immune dysregulation: On the border between allergy and immunodeficiency Stephen Jolles (United Kingdom)

Allergen immunotherapy > Clinical Allergology > Pediatrics

Pro & Con Sessions (P & C)

P & C 3 Long-term placebo-controlled studies are needed in children and are ethical to approve novel immunotherapy products Monday, 3 June 2019

12:30-13:00 hrs Room Pro & Con Arena (FIL)

Chair Mohamed Shamji (United Kingdom)

Pro Vera Mahler (Germany)

Con Sergio Bonini (Italy)

Company Sponsored Mini Symposia (CSMS)

CSMS 3 Monday, 3 June 2019

12:45-13:15 hrs Room Hall 11 (FIL)

Company Sponsored Mini Symposia (CSMS)

CSMS 4 Monday, 3 June 2019

12:45-13:15 hrs Room Hall 12 (FIL)

Food allergy > Clinical Allergology > Pediatrics > Basic Allergology

Pro & Con Sessions (P & C)

P & C 4 Oral immunotherapy to foods: Ready for clinical practice? Monday, 3 June 2019

13:00-13:30 hrs Room Pro & Con Arena (FIL) Chair Helen A Brough (United Kingdom)

Pro Giovanni Battista Pajno (Italy)

Con Montserrat Alvaro Lozano (Spain)

Company Sponsored Symposia (CSS)

CSS 7 Monday, 3 June 2019

13:45-15:15 hrs Room Hall 8 (FIL Meeting Centre)

Allergen immunotherapy > Clinical Allergology > ENT > Precision Medicine

Interactive Symposia (ISYM)

ISYM 2 Rethinking our approach to develop new disease modifying therapeutics for respiratory diseases Monday, 3 June 2019

13:45-15:15 hrs Room Hall 7 (Altice Arena)

Chairs Ralph Mösges (Germany) Oliver Pfaar (Germany)

Immunotherapy: A prototype of precision medicine Robyn O'Hehir (Australia)

Novel approaches of allergen immunotherapy for respiratory diseases Peter Socrates Creticos (United States)

Clinical and paraclinical effects of allergen immunotherapy: Do we really need a placebo? Lars Jacobsen (Denmark)

Pediatrics > Drug allergy > Clinical Allergology > Allied health and primary care

Interactive Workshops (IWS)

IWS 5 Managing a child with possible allergy to a vaccine Monday, 3 June 2019

13:45-15:15 hrs Room Hall 6 (Altice Arena)

Chairs Marina Atanaskovic-Markovic (Serbia) Luis Miguel Borrego (Portugal)

Food allergy and allergy to vaccine: A myth? Susanne Gabriele Lau (Germany)

How to investigate a child with a possible allergy to vaccine Odilija Rudzeviciene (Lithuania)

Clinical Allergology > Basic Allergology > Clinical Immunology > Allied health and primary care

Junior Members Assembly Symposia (JMA SYM)

JMA Edu JMA Educational Session: Training in allergology across Europe Monday, 3 June 2019

13:45-15:15 hrs Room Hall 9 (FIL)

Chairs Pasquale Comberiati (Italy) Thulja Trikamjee (South Africa)

The undergraduate education and EAACI Allergy College project Ibon Eguiluz-Gracia (Spain)

The postgraduate education: Milestones and training centers Marta Vazquez-Ortiz (United Kingdom)

The training in pediatric allergology: Specific requirements Alberto Alvarez-Perea (Spain)

What distinguishes allergy specialty from other specialties related to allergy Enrico Heffler (Italy)

Allergen immunotherapy > Clinical Allergology > Food allergy > Clinical Immunology

Late Breaking Oral Abstract Sessions (LB OAS)

LB OAS 01 Novel approaches of immunotherapy Monday, 3 June 2019

13:45-15:15 hrs Room Hall 13 (FIL)

Chairs Adam M Chaker (Germany) Mark Larché (Canada)

Session roadmap Adam M Chaker (Germany)

Intralymphatic allergen immunotherapy against birch and grass pollen allergy. A 3-year double-blind randomized clinical trial of 72 patients. Lars Ahlbeck (Sweden)

The allergenicity and immunogenicity of peanut and house dust mite peptides generated by a novel technology platform: The future of immunotherapy treatments Janice Anastasia Layhadi (United Kingdom)

SLIT with rMal d 1 but not rBet v 1 induces antibodies blocking IgE-binding to the apple allergen Gabriela Sánchez Acosta (Austria)

Safety and tolerability of epicutaneous immunotherapy (EPIT) for peanut allergy: Analysis from two phase 3 clinical trials Amy Scurlock

Nasal allergen neutralizing antibodies correlate closely with tolerated intranasal allergen challenge dose following grass pollen subcutaneous immunotherapy in patients with local allergic rhinitis Rebecca V Parkin (United Kingdom)

Food allergy > Allergen immunotherapy > Allied health and primary care > Clinical Allergology

Late Breaking Poster Discussion Sessions (LB PDS)

LB PDS 04 Food Allergy: Cutting-edge concepts Monday, 3 June 2019

13:45-15:15 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Kirsten Beyer (Germany) Stephen Till (United Kingdom)

Allergy to Peanut ImPacting Emotions And Life (APPEAL) 2: The first European multi-country qualitative evaluation of the impact of living with peanut allergy Audrey DunnGalvin (Ireland)

The crystal structure of the Thaumatin-like protein (TLP) allergen Jun a 3 and a glimpse on TLPs from other species and their role as putative allergens Markus Eder (Austria)

Association between diet diversity, eczema and fillagrin mutations and food allergy in the first decade of life Carina Venter (United States)

Predictors for late tolerance development in food protein induced allergic proctocolitis Ozge Soyer (Turkey)

A role for early oral exposure to house dust mite allergens through breastmilk in food allergy susceptibility Patricia Macchiaverni

Food protein-induced enterocolitis syndrome A Portuguese multicenter study Paulo Ribeiro Santos

Variable impact of food matrices on protease resistance of different allergenic and non-allergenic food proteins Jaap Akkerdaas (The Netherlands)

Experience with omalizumab in patients with anaphylactic reactions to milk allergy Ana Prieto-Moreno Pfeifer (Spain)

Computer based diagnosis and management algorithm for cow’s milk protein allergy (CMPA) in primary care in United Kingdom- a proof of concept study Samudra Mukherjee (United Kingdom)

Severity of allergic reactions during build-up phase of milk oral immunotherapy Ismael Gómez García (Spain)

Oral immunotherapy for peanut allergy: A systematic review and meta-analysis Derek K Chu (Canada)

Development of a model for predicting allergenicity of new and modified proteins Kitty Verhoeckx (The Netherlands)

Adverse allergic reactions during build-up phase of milk oral immunotherapy Paloma Jaqueti Moreno (Spain)

Enzymatic support of gastric digestion alleviates clinical symptoms and enhances efficacy of oral immunotherapy in food allergy Nazanin Samadi (Austria) Food avoidance counselling in LTP allergy: are in vivo and in vitro tests of any help? Márcio André Mesquita (Portugal)

ENT > Biologicals > Basic Immunology > Basic Allergology

Oral Abstract Sessions (OAS)

OAS 15 CRS from bench to bedside Monday, 3 June 2019

13:45-15:15 hrs Room Hall 12 (FIL)

Chairs Peter Valentin Tomazic (Austria) Jose Ferreira (Portugal)

Session roadmap Peter Valentin Tomazic (Austria)

Topographical diversity of the upper respiratory tract microbiome in chronic rhinosinusitis patients Katleen Martens (Belgium)

Broad immunglobulin G repertoire in chronic rhinosinusitis with nasal polyps regulates pro-inflammatory IgE responses Janice Anastasia Layhadi (United Kingdom)

IL-25 mediated Th2-biased inflammation in nasal polyps: role of respiratory virus infection and its modulation by interferon-alpha Hong Haiyu (China)

Real-life assessment of chronic rhinosinusitis patients using mobile technology Sven F Seys (Belgium)

Poor long-term effect of aspirin treatment on chronic rhinosinusitis with nasal polyps in patients with NSAID- exacerbated respiratory disease Sanna Toppila-Salmi (Finland)

Dupilumab efficacy in patients with severe chronic rhinosinusitis with nasal polyposis: Pooled results from the SINUS-24 and SINUS-52 phase 3 studies Claus Bachert (Belgium)

Allied health and primary care > Clinical Allergology > Allergy diagnosis and systems medicine

Oral Abstract Sessions (OAS)

OAS 16 Strategies to reduce the impact of allergic disease Monday, 3 June 2019

13:45-15:15 hrs Room Hall 14 (FIL)

Chairs Inger Kull (Sweden) Jaime Correia de Sousa (Portugal)

Session roadmap Inger Kull (Sweden)

Impact of allergic diseases at the emergency room in Padua University Hospital during the decade 2008-2017 ilaria lazzarato (Italy)

Awareness of 119 (911) rescue team on anaphylaxis and asthma exacerbations in Korea: Before and after the education Yoon-Seok Chang (South Korea)

Psychological factors associated with quality of life and burden in parents of children with food allergy Christina J Jones (United Kingdom)

Sequential nut oral food challenges improves the quality of life of nut-allergic children François Graham (Switzerland)

Long-term longitudinal impact of probiotic peanut oral immunotherapy (PPOIT) on patient quality of life at 4 years post-treatment Audrey DunnGalvin (Ireland)

Management of allergic rhinitis in community pharmacy - a systematic literature review Olga Lourenço (Portugal)

Allergy diagnosis and systems medicine > ENT > Precision Medicine > Basic Allergology

Poster Discussion Sessions (PDS)

PDS 14 Molecular allergology for in vitro diagnostics Monday, 3 June 2019

13:45-15:15 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Jörg Kleine-Tebbe (Germany) Zeynep Ulker Tamay (Turkey)

The prevalence of IgE sensitization against 112 allergen molecular components (ISAC) and the risk of asthma by 10.5 years of age in a finnish birth cohort Asko Eemeli Oksanen (Finland)

Children mono-sensitized to Can F 5 show different reactions to male- and female dog extract provocation: A randomized, double blind controlled trial Ann-Marie Malby Schoos (Denmark)

Efficacy of sublingual immunotherapy in children with birch pollen allergy and different IgE profiles to recombinant component-resolved allergens Oksana Ereshko (Russia)

Evaluation of IgE reactivities of allergen homologous molecules from Japanese hop pollen Ji Eun Yuk (South Korea)

IgG removal significantly enhances detection of microarray allergen-specific IgE reactivity in patients’ serum Joana Vitte (France, Metropolitan)

Diagnostic capacity analysis for a whole extract and component allergen based microarray test in pollen and plant-food allergy Paola L Quan (Spain)

IgE of birch pollen allergic patients recognize conformational epitopes of Bet V 1 whereas IgG antibodies react with non-conformational epitopes Anna A Iliukhina (Russia)

Production of nature-identical Bet V 1 and Ara H 2 using a plant-based transient expression system Öykü Üzülmez (Turkey)

Facilitated expression and purification of two unfolded recombinant Bet V 1 fragments in escherichia coli Anna A Iliukhina (Russia) Allergen aggregates consisting of Bet V 1 and Phl P 5 exhibit reduced allergenic activity due to altered presentation of IgE epitopes Sabine Flicker (Austria)

Human IgE monoclonal antibodies for epitope mapping of Der P 2 Anna Pomés (United States)

Expression and purification of a panel of recombinant cat allergens Kseniia Riabova (Russia)

Pediatrics > Asthma > Clinical Allergology

Poster Discussion Sessions (PDS)

PDS 15 Risk factors and treatment of asthma in children Monday, 3 June 2019

13:45-15:15 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Umit Sahiner (Turkey) Silvia Sanchez-Garcia (Spain)

Association of sensitization to different aeroallergens with location of airway dysfunction and nasal volume in urban children Shinhae Lee (South Korea)

Obesity, metabolic syndrome, and lung function in Korean children and adolescents: The Korea national health and nutrition examination surveys 2009-2011 Minji Kim (South Korea)

Allergen sensitization profile of children with asthma and allergic rhinitis in vellore district of Tamilnadu, India narmada seshadri (India)

Moisture damage related fungal microbiota and new-onset wheezing in children Anne M Karvonen (Finland)

High prevalence of atopic asthma in rural malagasy children Sabina Illi (Germany)

Genetic polymorphism of IL17A/F genes in the pathogenesis of asthma in Siberian children Sergey Yurievich Tereshchenko (Russia)

Time trend prevalence of asthma among elementary school students in Southern Taiwan from 2004 to 2018 WeiYu Chen (Taiwan)

Dietary antioxidant intake and lung function development from school-age to adolescence Emmanouela Sdona (Sweden)

Patterns of sensitization among children with allergic rhinitis S. Tolga Yavuz (Germany)

Asthma mortality in Brazilian children and adolescents and seasonal variation (1996- 2016) Raquel Pitchon (Brazil)

Association of nebulized budesonide with hospital resource utilization in children with acute exacerbation of asthma Kunling SHEN (China)

The factors affecting duration of hospitalization due to the asthma attack in children Irem Turgay Yagmur (Turkey)

Comparative analysis of the causes of influencing a decrease in adherence to anti-asthma therapy in children with bronchial asthma Natalya Ilyenkova (Russia)

Evaluation of the relationship between asthma control and bronchodilator response in children with asthma Ilknur Kulhas Celik (Turkey)

Cognitive function in relation to symptoms and quality of life in children with seasonal allergic rhinitis during season and off season Georgia Papapostolou (Sweden)

The knowledge levels and habits about using short-acting bronchodilator before hospital admission of parents of children with asthma attack Ilknur Kulhas Celik (Turkey)

Allergen immunotherapy > Basic Allergology > Clinical Allergology > Precision Medicine

Poster Discussion Sessions (PDS)

PDS 16 Insect venom allergy Monday, 3 June 2019

13:45-15:15 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Maria Elisa Pedro Fernandes (Portugal) Darío Antolín-Amérigo (Spain)

No effect of antihypertensive drugs on severity of anaphylaxis and side-effects during venom immunotherapy Lisa Arzt-Gradwohl (Austria)

Secondary prevention measures in anaphylaxis patients - data from the european anaphylaxis registry Magdalena Kraft (Germany)

Predictors of severe adverse events and treatment failures during venom immunotherapy Peter Kopac (Slovenia)

Diagnostic value of serum CCL2 in anaphylaxis Romana Vantur (Slovenia)

The rate of adverse events is comparable between simultaneous bee and vespid venom immunotherapy and bee venom mono-immunotherapy Urban Cerpes (Austria)

Differences and similarities between large local reactions and systemic sting reactions Patrik Tripolt (Austria)

Does the site of hymenoptera sting influence the severity of anaphylactic reaction ? Radoslaw Gawlik (Poland)

Linear epitope mapping of different Api m 10-isoforms with overlapping peptide arrays identifies highly conserved IgE-binding motive in most isoforms Kathrin Elisabeth Paulus (Germany)

Search for immune response biomarkers in bee venom allergic condition Berta Ruiz León (Spain)

Characterization of the sensitization profile of honeybee sting allergic patients Catarina Pereira Coutinho (Portugal)

Purification and characterization of vespa velutina venom components, and comparison with the known allergens of other hymenoptera species RAFAEL MONSALVE (Spain)

Shedding light on the polistes dominula venom proteome - identification and characterization of novel allergens Johannes Grosch

Preliminary studies on the venom of the yellow-legged hornet vespa velutina nigrithorax Elisabetta Francescato (Italy)

Basophil activation testing as a biomarker for diagnostic and prognostic evaluation of ant (myrmecia pilosula) venom anaphylaxis before and after immunotherapy Thanh-Thao Adriana Le (Australia)

Basophil CC chemokine receptor 2 (CCR2) expression in hymenoptera venom anaphylaxis Ana Koren (Slovenia)

The recall of stinging insects and its association with the venom immunotherapy extract selection: A pediatric perspective Mattia Giovannini (Italy)

Sister Society Symposia (SSS)

SSS 6 EAACI- WAO Joint Symposium: World Allergy Forum: Innovations in food allergy treatment Monday, 3 June 2019

13:45-15:15 hrs Room Hall 10 (FIL)

Chairs Ioana Octavia Agache (Romania) Ignacio J. Ansotegui (Spain)

Immune mechanisms in skin immunotherapy Mario Sanchez-Borges (Venezuela)

Immunotherapy routes in clinical practice Alessandro Fiocchi (Vatican City)

Allergen immunotherapy through the skin Motohiro Ebisawa (Japan)

Sister Society Symposia (SSS)

SSS 7 EAACI - BSACI Joint Symposium: Allergic diseases: Focus on prevention, phenotype and disease modifying treatment Monday, 3 June 2019

13:45-15:15 hrs Room Hall 11 (FIL)

Chairs Adam Fox (United Kingdom) Luís Delgado (Portugal)

The challenges of preventing food allergy: Lessons learned from LEAP and EAT Helen A Brough (United Kingdom)

Pediatric Asthma: From Phenotype Discovery to Clinical Practice Adnan Custovic (United Kingdom)

Allergen immunotherapy: from mechanisms to immune monitoring biomarker selection Mohamed Shamji (United Kingdom)

Basic Immunology > Clinical Immunology > Pediatrics Symposia (SYM)

SYM 19 T cell repertoire and T cell tolerance in humans: From basic to clinic Monday, 3 June 2019

13:45-15:15 hrs Room Hall 1 (Altice Arena)

Chairs Carsten Schmidt-Weber (Germany) Stefanie Eyerich (Germany)

T cell heterogeneity and repertoire in human diseases Roger Geiger (Switzerland)

The role of regulatory T cells subsets in allergic inflammation Talal Chatila (United States)

Regulatory T cells in primary immunodeficiencies Raffaele Badolato (Italy)

Pediatrics > Clinical Allergology > Asthma

Symposia (SYM)

SYM 20 The impact of physical exercises on respiratory symptoms: Problems and solutions Monday, 3 June 2019

13:45-15:15 hrs Room Hall 2 (Altice Arena)

Chairs Stefano R Del Giacco (Italy) Matteo Bonini (Italy)

The “running” nose Valerie Hox (Belgium)

Non-allergic mechanisms of exercise-induced bronchoconstriction Mariana Couto (Portugal)

The young asthmatic dreaming to become an athlete Leif Bjermer (Sweden)

Biologicals > Clinical Allergology > Clinical Immunology > Pediatrics

Symposia (SYM)

SYM 21 Therapeutic approaches in management of eosinophilic esophagitis Monday, 3 June 2019

13:45-15:15 hrs Room Hall 3 (Altice Arena)

Chairs Ingrid Terreehorst (The Netherlands) Mirna Chehade (United States)

Current pharmacological treatment Albert Jan Bredenoord (The Netherlands)

Biologicals: From the bench to bedside Antonella Cianferoni (United States)

Nutritional management: Focusing on nutrition instead of allergens Carina Venter (United States)

Dermatology > Clinical Allergology > Clinical Immunology

Symposia (SYM)

SYM 22 Cross reactivity in drug hypersensitivity Monday, 3 June 2019

13:45-15:15 hrs Room Hall 5 (Altice Arena)

Chairs Knut Brockow (Germany) Josefina Maria Rodrigues Cernadas (Portugal)

Betalactam antibiotics Antonino Romano (Italy)

Corticosteroids Annick Barbaud (France)

Cyclo-oxigenase inhibitors Aleksandra Wardzynska (Poland)

ENT > Asthma > Precision Medicine

Thematic Symposia (TSYM)

TSYM 4 NSAIDs-Exacerbated Respiratory Disease (NERD) - practical approaches to diagnosis and management Monday, 3 June 2019

14:00-15:15 hrs Room Hall 4 (Altice Arena)

Chairs Joaquim Mullol (Spain) Martin Wagenmann (Germany)

Pathophysiology of asthma endotype associated with hypersensitivity to NSAIDs Hae-Sim Park (South Korea)

CRS and nasal polyps in patients with N-ERD Ludger Klimek (Germany)

New approaches to management of a patient with N-ERD Marek L Kowalski (Poland) Highlights Sessions (HS)

HS 2 Highlights on Food Allergy: Increase of threshold dose upon OIT- what is clinical meaningful? Monday, 3 June 2019

15:20-15:35 hrs Room Pro & Con Arena (FIL)

Chair Giovanni Battista Pajno (Italy)

Interview on the topic: Increase of threshold dose upon OIT- what is clinical meaningful? George du Toit (United Kingdom)

Company Sponsored Symposia (CSS)

CSS 8 Monday, 3 June 2019

15:45-17:15 hrs Room Hall 8 (FIL Meeting Centre)

Dermatology > Biologicals

Hot Topic Sessions (HT)

HT 4 Biological in atopic dermatitis and mast cell diseases- where are we? Monday, 3 June 2019

15:45-17:15 hrs Room Hall 9 (FIL)

Chairs Peter Schmid-Grendelmeier (Switzerland) Oscar Palomares (Spain)

Atopic dermatitis endotypes and implications for targeted therapeutics Désirée Erlinda Sophia Larenas-Linnemann (Mexico)

Biologicals on the marked for atopic dermatitis Natalija Novak (Germany)

Novel treatment modalities in mast cell diseases Martin Church (United Kingdom)

Dermatology > Basic Immunology > Clinical Immunology > Precision Medicine

Interactive Workshops (IWS)

IWS 6 Hereditary Angioedema (HAE) – from pathways to management Monday, 3 June 2019

15:45-17:15 hrs Room Hall 6 (Altice Arena) Chairs Manuel Branco Ferreira (Portugal) Tabi Leslie (United Kingdom)

“Hunting” for a new pathway in HAE – the angiopoietin-1 gene mutation Stefano R Del Giacco (Italy)

Current management and prophylaxis of HAE Timothy Craig (United States)

Asthma > Pediatrics > Clinical Allergology > Biologicals

Late Breaking Poster Discussion Sessions (LB PDS)

LB PDS 05 Novel insights on pathophysiology of asthma Monday, 3 June 2019

15:45-17:15 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Suzanne Bal (The Netherlands) Jasper Kappen (The Netherlands)

Distinctive lung function trajectories from age 10 to 26 years in men and women and associated early life risk factors – a birth cohort study Wilfried Karmaus (United States)

Predicting risk for thunderstorm asthma in patients with seasonal allergic rhinitis: The TAISAR study Ju Ann Tan (Australia)

Therapeutic switch from omalizumab to mepolizumab in patients with uncontrolled severe eosinophilic asthma: Responder analysis Frank Albers (United States)

Therapeutic switch from omalizumab to mepolizumab in patients with uncontrolled severe eosinophilic asthma: Treatment effect by nasal polyps, aspirin/NSAID intolerance, and GERD Frank Albers (United States)

Blood ILC1s correlate with bad lung function in severe asthmatic patients Anne-Charlotte Jonckheere (Belgium)

Effect of benralizumab on the immune response in patients with severe eosinophilic asthma Sematonyte Justina (Lithuania)

Virus-induced asthma/wheeze in preschool children: Longitudinal assessment of airflow limitation by the Impulse Oscillometry System George Konstantinou (Greece)

Immunoallergic study and correlation with prognostic factors in severe eosinophilic asthma Maria Basagana (Spain)

Association between disease severity, asthma control and obesity in children and adults Melike Kahveci (Turkey)

Bronchodilator responsiveness in healthy children: Insights from a cross-sectional study Tiago Azenha Rama (Portugal)

Asthma in the elderly - a comparison between patients with early-onset and late-onset asthma Cátia Santa (Portugal)

Methilation and expression of TLR2 and TLR4 and their role in asthma Oxana A. Svitich (Russia)

Anti-IL-5 treatment of asthma and chronic sinusitis with nasal polyps patients as a feasibility to achieve control in both conditions Ksenia Pavlova (Russia)

Analysis of allergen spectrum and co-sensitivity in patients with respiratory allergic diseases: The first application of microfluidic chip detector Zhifeng Huang (China)

Asthma > ENT > Pediatrics

Oral Abstract Sessions (OAS)

OAS 17 Risk factors and novel treatments for children with respiratory allergies Monday, 3 June 2019

15:45-17:15 hrs Room Hall 7 (Altice Arena)

Chairs Silvia Sanchez-Garcia (Spain) Susanne Gabriele Lau (Germany)

Session roadmap Silvia Sanchez-Garcia (Spain)

Does grandmother’s smoking influence asthma risk in the grandchild? A systematic review and meta-analysis Guo-Qiang Zhang (Sweden)

High-dose vitamin D supplementation during pregnancy and asthma at age 6: A randomized controlled trial Bo L Chawes (Denmark)

Efficacy of inhaled salbutamol with and without prednisolone for first acute rhinovirus-induced wheezing episode Tuomas Jartti (Finland)

Tiotropium a new treatment option for severe uncontrolled pre-school asthma Stefan Zielen (Germany)

The Effect Of Polivalent Mechanical Bacterial Lysate On The Clinical Course Of Pollen Allergic Rhinitis In Children. Kamil Piotr Janeczek (Poland)

Immune, microbial, atopic characteristics and epithelial integrity in children with adenoid hypertrophy Milos Jesenak (Slovakia)

Allergen immunotherapy > Precision Medicine > Basic Allergology > Clinical Immunology

Oral Abstract Sessions (OAS)

OAS 18 Allergen immunotherapy: Mechanisms and biomarkers Monday, 3 June 2019

15:45-17:15 hrs Room Hall 10 (FIL)

Chairs Mohamed Shamji (United Kingdom) Mübeccel Akdis (Switzerland)

Session roadmap Mohamed Shamji (United Kingdom) MiR-8485 is locally upregulated upon allergen-specific immunotherapy and coincides with shifted Breg/Th17 balance Constanze A. Jakwerth (Germany)

Epigenetic changes in SATB1 gene in FoxP3+ regulatory T cells reflect immunetolerance status during grass pollen subcutaneous and sublingual immunotherapy Madison Lenormand (United Kingdom)

The frequency of allergen-specific T regulatory cells before AIT is associated with treatment response Pawel Gajdanowicz (Poland)

Der P 23 shows limited IgE diagnostic value and does not appear to impact clinical outcomes of HDM sublingual allergy immunotherapy Peter Sejer Andersen (Denmark)

Altered chromatin landscape in T follicular cells in seasonal allergic rhinitis and following allergen-specific immunotherapy Hanisah Sharif (United Kingdom)

The FAB-assay - useful tool for evaluating successful immunotherapy or reflection of specific-IgG4? Melanie Mertens-Beer (Germany)

Basic Allergology > Basic Immunology

Oral Abstract Sessions (OAS)

OAS 19 Avenues in immunomodulation Monday, 3 June 2019

15:45-17:15 hrs Room Hall 12 (FIL)

Chairs Milena Sokolowska (Switzerland) Santiago Quirce (Spain)

Session roadmap Milena Sokolowska (Switzerland)

Immunomodulatory effects of adipose stem cells-derived extracellular vesicles on Th2-mediated inflammation in lung epithelial cells Sue Jean Mun (South Korea)

The cannabinoid receptor agonist WIN55,212-2 impairs peanut-induced allergic features by promoting the generation of tolerogenic dendritic cells Alba Angelina Querencias (Spain)

PP-001, a new small molecule for intraocular treatment of uveitis - preclinical data and first results of a prospective multicenter clinical trial Stephan Thurau (Germany)

STAT3 gene suppression as an approach for the treatment of non-eosinophilic bronchial asthma Aleksandr Nikolskii (Russia)

Identification of nut lipid specific NKT receptors and their role on the intrinsic allergenicity of nut proteins rui wang (United Kingdom)

ENT > Basic Allergology > Clinical Allergology

Oral Abstract Sessions (OAS) OAS 20 Pathophysiology and diagnosis of allergic rhinitis Monday, 3 June 2019

15:45-17:15 hrs Room Hall 13 (FIL)

Chairs Paloma Campo (Spain) Brecht Steelant (Belgium)

Session roadmap Paloma Campo (Spain)

Association of the CD14 (-159C/T) SNP with house dust mites sensitization in patients with perennial allergic rhinitis in the population of ukraine Taras Petrovych Baranovskyi (Ukraine)

Replication study of susceptibility variants associated with allergic rhinitis and allergy yuan zhang (China)

Severe respiratory allergic patients undergo oral mucosa remodelling prior to food allergy Javier Sanchez Solares (Spain)

Perennial allergy induces eosinophilia in polyps but not in nasal mucosa María Isabel Delgado Dolset (Spain)

A combination corticosteroid and antihistamine targets key innate immune pathways at the nasal mucosa in allergic rhinitis Pete K Smith (Australia)

Clinical Immunology > Basic Immunology

Poster Discussion Sessions (PDS)

PDS 17 Mechanisms and treatment in clinical immunology Monday, 3 June 2019

15:45-17:15 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Isabella Quinti (Italy) Anna Sediva (Czech Republic)

The effect of vitamin D and UV-light-exposure on immune development in infancy Kristina Rueter (Australia)

Idiopathic CD4 lymphocytopenia – clinical and laboratory characteristics Jirí Litzman (Czech Republic)

Low bone mineral density and muscle mass in common variable immunodeficiency patients: Association with CD4+T cells and B cells Henrikki Gomes Antila (Brazil)

Clinical phenotype of elderly patients with common variable immunodeficiency Chiara Gelardi (Italy)

Alteration in the proportions of circulating follicular T helper cell subsets is related to aberrant B cell distribution and antibody production in patients with systemic lupus erythematosus Krisztina Szabó (Hungary)

The imbalance of peripheral follicular T helper cell subsets is associated with abnormal B-cell distribution and disease severity in primary sjögren’s syndrome Ilona Jámbor (Hungary) Features of cellular immunity in chronic atrophic gastritis Sergey Yurievich Tereshchenko (Russia)

Drug allergy > Pediatrics

Poster Discussion Sessions (PDS)

PDS 18 Drug hypersensitivity in children Monday, 3 June 2019

15:45-17:15 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Eva Gomes (Portugal) Ingrid Terreehorst (The Netherlands)

Allergic reaction to antibiotics in children is rare. Results from oral provocations tests at children’s hospital in Iceland Gyda Katrin Gudnadottir (Iceland)

Diagnostic evaluation of turkish children with beta-lactam allergy suspicion: Role of reagents and prolonged provocation tests Tugba Arikoglu (Turkey)

Characterization of beta-lactam allergy in pediatrics in the immunoallergology outpatient department Tatiana Lourenço (Portugal)

Oral challenge in children with suspected betalactam allergy: With or without skin tests? António Jorge Cabral (Portugal)

Skin and drug provocation test results in children with suspected Beta-Lactam allergy Burçin Beken (Turkey)

Hypersensitivity reactions to beta-lactam in children: Diagnostic approach in a 6-year sample Joana Carvalho (Portugal)

Suspected drug hypersensitivity in pediatric age and allergic diseases Inês Machado Cunha (Portugal)

DRESS syndrome in children: A rare entity Haifa Ben Romdhane (Tunisia)

Adverse drug reactions in adolescents Inês Machado Cunha (Portugal)

Cytostatic agents in pediatric population experience in a third level hospital in Madrid Ana Montoro-Ferrer (Spain)

Can we safely desensitize children to chemotherapy? Revision of 98 treatments Maria João Vasconcelos (Portugal)

What is the role of serum and skin testing in children with a parent reported beta-lactam allergy? Kristina Rueter (Australia)

Food allergy > Basic Allergology

Poster Discussion Sessions (PDS)

PDS 19 Profiling food allergens Monday, 3 June 2019

15:45-17:15 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Heimo Breiteneder (Austria) Ronald van Ree (The Netherlands)

Identification of novel allergens in the North Sea shrimp crangon crangon Thomas Holzhauser (Germany)

Analysis of IgE-antibody to Ana O 3 on the microarray is useful in predicting cashew oral food challenge failure Sakura Sato (Japan)

PR-10, NsLTP, 2S-Albumin, DC-8 and vicilin from chickpea (cicer arietinum) display IgE-reactivity and likely contribute to cross-reactivity with legume foods Andrea Wangorsch (Germany)

The potential immunomodulatory activity of titanium dioxide and other food and drug dyes Natalia Aliakhnovich (Belarus)

Sensitization profile of cricket food-allergic or cricket tolerant patients in an entomophagous population in Niamey, Niger Romy Mariette Marie Joseph Gadisseur (Belgium)

Combining peach allergen components such as Pru P 7 makes it possible to predict severity by peach allergy in Japanese children and adolescence Yusuke Ando (Japan)

Shrimp allergy in a pediatric population: Tropomyosin and beyond Carla Torán Barona (Spain)

Shrimp sensitization in house dust mite allergic patients Natalia Ewa Ukleja-Sokolowska (Poland)

House dust mite in atopy: A confusing factor in shrimp allergy José Roberto Mendes Pegler (Brazil)

Peanut allergy: Co-sensitization, co-allergy, and tolerance to tree nuts Maria Luís Marques (Portugal)

Comparison Of ImmunoCAP And ISAC Component Testing For The Diagnosis Of Hazelnut, Pistachio, And Cashew Allergy. François Graham (Switzerland)

Epitope-specific antibody binding on major Hen’s egg-white allergen, ovomucoid, using novel multiplex immunoassay Maria Suprun (United States)

Differential IgE sensitization to the prawn allergen hemocyanin among food allergic patients and seafood processing workers Sandip D Kamath (Australia)

Low molecular weight components from fish modify physical and immunological properties of the bronchial epithelium Tanja Kalic (Austria)

Sister Society Symposia (SSS)

SSS 8 EAACI-ERS Joint Symposium: Asthma: A multidisciplinary disease Monday, 3 June 2019

15:45-17:15 hrs Room Hall 5 (Altice Arena) Chairs Zuzana Diamant (The Netherlands) Antonio Spanevello (Italy)

Asthma in a pediatrician´s office setting Paraskevi Xepapadaki (Greece)

Asthma in an allergologist´s office setting Alberto Alvarez-Perea (Spain)

Asthma in a tertiary hospital Apostolos Bossios (Sweden)

Environmental and occupational allergy > Allied health and primary care > Clinical Allergology

Symposia (SYM)

SYM 23 30 years of hygiene hypothesis: Past, present and future Monday, 3 June 2019

15:45-17:15 hrs Room Hall 1 (Altice Arena)

Chairs Jon Genuneit (Germany) Paolo Matricardi (Germany)

Emerging concepts in hygiene hypothesis Adnan Custovic (United Kingdom)

Environmental diversity: Key to prevention of allergy André Moreira (Portugal)

Hygiene hypothesis and the epidemic of allergy Gary W.K Wong (Hong Kong SAR)

ENT > Ocular Allergy > Clinical Allergology

Symposia (SYM)

SYM 24 Allergic rhinitis impacts more than the airways Monday, 3 June 2019

15:45-17:15 hrs Room Hall 2 (Altice Arena)

Chairs Philippe Gevaert (Belgium) Sanna Toppila-Salmi (Finland)

Impact of airway inflammation on olfaction Joaquim Mullol (Spain)

Middle ear effusion in allergic rhinitis Peter Valentin Tomazic (Austria)

Ocular impact of topical nasal treatment Banu Bozkurt (Turkey) Clinical Allergology > Basic Immunology > Clinical Immunology > Pediatrics

Symposia (SYM)

SYM 25 Insect venom allergy and mastocytosis Monday, 3 June 2019

15:45-17:15 hrs Room Hall 3 (Altice Arena)

Chairs Gunter Sturm (Austria) Thilo Jakob (Germany)

Mastocytosis: Overview and pathophysiology Marcus Maurer (Germany)

When to think of mastocytosis in insect venom allergy? Patrizia Bonadonna (Italy)

Therapeutic challenges in mastocytosis Hanneke Oude Elberink (The Netherlands)

Pediatrics > Asthma > Clinical Allergology

Symposia (SYM)

SYM 26 Integrated care for the allergy patient Monday, 3 June 2019

15:45-17:15 hrs Room Hall 4 (Altice Arena)

Chairs Jean-Christoph Caubet (Switzerland) Glenis Kathleen Scadding (United Kingdom)

Recognizing co-morbidities – a success story in asthma management João Almeida Fonseca (Portugal)

Pediatric allergy – early recognition and management Karin Lødrup Carlsen (Norway)

Model of integrated care for the allergic patient Elizabeth Ann Angier (United Kingdom)

Pediatrics > Food allergy

Year in Review Sessions (YIR)

YIR 5 Year in Review: Pediatrics Monday, 3 June 2019

15:45-17:15 hrs Room Hall 14 (FIL) Chairs Robert Boyle (United Kingdom) Susanne Halken (Denmark)

Diagnostic approach in beta-lactam hypersensitivity in children - Are there any controversies? Marina Atanaskovic-Markovic (Serbia)

Anaphylaxis in children Jonathan O'B Hourihane (Ireland)

Targeting the skin for food allergy prevention Robert Boyle (United Kingdom)

Business Meetings (BM)

BM 13 Interest Group Environmental & Occupational Allergy - Open to all attendees Monday, 3 June 2019

17:30-18:40 hrs Room Hall 7 (Altice Arena)

Introductory lecture: Implementing a personalized approach in occupational allergy Vera Mahler (Germany)

Business Meetings (BM)

BM 14 Working Group Eosinophilic Esophagitis - Open to all attendees Monday, 3 June 2019

17:30-18:40 hrs Room Hall 11 (FIL)

Introductory lecture: Eosinophilic esophagitis and other eosinophilic disorders in the : Diagnostic and therapeutic approach Mirna Chehade (United States)

Business Meetings (BM)

BM 15 Working Group Epidemiology - Open to all attendees Monday, 3 June 2019

17:30-18:40 hrs Room Hall 12 (FIL)

Introductory lecture: A snapshop of allergy in urban and rural settings in Africa Michael Levin (South Africa)

Report of the Chair: review of activities

Specific Reports on the ongoing EAACI Task Forces with involvement of the WG Epidemiology

Involvement of the WG in collaborative publications

Report of the Chair: planned activities Business Meetings (BM)

BM 16 Interest Group Drug Allergy - Open to all attendees Monday, 3 June 2019

17:30-18:40 hrs Room Hall 14 (FIL)

Report of the IG Drug Allergy Marina Atanaskovic-Markovic (Serbia)

Introductory lecture: Genetic variants associated with drugs induced hypersensitivity reactions Jean-Louis Guéant (France)

Sister Society Symposia (SSS)

SSS 10 EAACI – ANS Joint Symposium: Allergy in Africa: Respiratory allergy in Africa Monday, 3 June 2019

17:30-19:00 hrs Room Hall 2 (Altice Arena)

Chair Andre Van Niekerk (South Africa)

Introduction: The Allergy in Africa Network Andre Van Niekerk (South Africa)

Asthma control in North Africa and the Middle East Habib Douagui (Algeria)

United Airway Disease in the Developing World Thulja Trikamjee (South Africa)

Changes in birth environment & downstream airway immune dysregulation - lessons for developing countries Andre Van Niekerk (South Africa)

Discussion and questions

Sister Society Symposia (SSS)

SSS 9 EAACI – GARD Joint Symposium: Improving health care in respiratory diseases Monday, 3 June 2019

17:30-19:00 hrs Room Hall 1 (Altice Arena)

Chairs José Rosado Pinto (Portugal) Nikolai Khaltaev (Switzerland)

Integration of respiratory health into primary health care Jaime Correia de Sousa (Portugal)

Air pollution and self management in allergies and asthma POLLAR Wienczyslawa Bozena Czarlewski (France) Establishing collaboration: The GARD-CPLP working group Claudia Conceição (Portugal)

Satellite Symposia (SAT)

SAT 10 Monday, 3 June 2019

17:45-19:15 hrs Room Hall 8 (FIL Meeting Centre)

Satellite Symposia (SAT)

SAT 11 Monday, 3 June 2019

17:45-19:15 hrs Room Hall 9 (FIL)

Satellite Symposia (SAT)

SAT 12 Monday, 3 June 2019

17:45-19:15 hrs Room Hall 10 (FIL)

Satellite Symposia (SAT)

SAT 7 Monday, 3 June 2019

17:45-19:15 hrs Room Hall 3 (Altice Arena)

Satellite Symposia (SAT)

SAT 8 Monday, 3 June 2019

17:45-19:15 hrs Room Hall 4 (Altice Arena)

Satellite Symposia (SAT)

SAT 9 Monday, 3 June 2019 17:45-19:15 hrs Room Hall 5 (Altice Arena)

Drug allergy

Learning Lounges (LL)

LL 10 Which skin tests can be used for delayed cutaneous adverse drug reactions? Tuesday, 4 June 2019

07:30-08:15 hrs Room Hall 12 (FIL)

Which skin tests can be used for delayed cutaneous adverse drug reactions? Annick Barbaud (France)

Pediatrics > Asthma

Learning Lounges (LL)

LL 11 How to evaluate lung function in the asthmatic child? Tuesday, 4 June 2019

07:30-08:15 hrs Room e-Poster Area A (FIL)

How to evaluate lung function in the asthmatic child? Luis Miguel Borrego (Portugal)

ENT > Precision Medicine

Learning Lounges (LL)

LL 12 Endotyping chronic rhinosinusitis for a better treatment approach Tuesday, 4 June 2019

07:30-08:15 hrs Room e-Poster Area C (FIL)

Endotyping chronic rhinosinusitis for a better treatment approach Claus Bachert (Belgium)

Dermatology

Learning Lounges (LL)

LL 9 Anti IgE for treatment of chronic urticaria Tuesday, 4 June 2019

07:30-08:15 hrs Room Hall 11 (FIL)

Anti IgE for treatment of chronic urticaria Clive Grattan (United Kingdom)

Pediatrics > Asthma > Basic Immunology > Basic Allergology

Plenary Symposia (PL)

PL 5 The link between allergy and the microbiome Tuesday, 4 June 2019

08:30-10:00 hrs Room Hall 1 (Altice Arena)

Chairs Liam O'Mahony (Ireland) Mimi L. K. Tang (Australia)

Neonatal gut microbiota associates with childhood multi–sensitisation and T cell differentiation Susan Lynch (United States)

Influence of lung microbiome on fungal associated asthma David Denning (United Kingdom)

Impact of diet-microbiome on mucus barrier and immune disorders Phil Hansbro (Australia)

Basic Immunology > Biologicals > Precision Medicine > Basic Allergology

Plenary Symposia (PL)

PL 6 Allergy today – Targeting barriers and tolerance Tuesday, 4 June 2019

08:30-10:00 hrs Room Hall 2 (Altice Arena)

Chairs Luís Delgado (Portugal) Peter Hellings (Belgium)

Barrier dysfunction – the “Achilles heel” of allergic diseases? Cezmi Akdis (Switzerland)

Targeting the molecules and mediators – “magic bullets” for allergy treatment Ioana Octavia Agache (Romania)

Biodiversity hypothesis and immune tolerance Tari Haahtela (Finland)

Clinical Allergology > Dermatology > ENT > Precision Medicine Thematic Symposia (TSYM)

TSYM 5 Allergy Session: Novel developments and highlights in allergy Tuesday, 4 June 2019

10:30-11:45 hrs Room Hall 4 (Altice Arena)

Chairs Cezmi Akdis (Switzerland) Maria J Torres (Spain)

Mechanisms of allergy development: Lessons learned from hematopoietic stem cell transplantation. Thomas Eiwegger (Canada)

Skin microbiome and transcriptome in atopic dermatitis Claudia Traidl-Hoffmann (Germany)

Treatable traits approach and biomarkers from asthma to chronic rhinosinusitis De Yun Wang (Singapore)

Company Sponsored Symposia (CSS)

CSS 9 Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 14 (FIL)

Precision Medicine > Asthma > Pediatrics

Hot Topic Sessions (HT)

HT 5 Epigenetics – the new frontier in asthma Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 13 (FIL)

Chairs Mohamed Shamji (United Kingdom) Luís Delgado (Portugal)

The epigenetic clock Ian Michael Adcock (United Kingdom)

Novel methodologies in cohort studies: Pros and cons Alkis Togias (United States)

Asthma > Pediatrics > Allied health and primary care > Clinical Immunology

Interactive Workshops (IWS) IWS 7 Management of asthma during pregnancy Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 6 (Altice Arena)

Chairs Silvia Sanchez-Garcia (Spain) Maria Elisa Pedro Fernandes (Portugal)

Immunological changes in pregnancy Sarah Alice ven Nederveen-Bendien (The Netherlands)

Managing and monitoring asthma during pregnancy Charlotte Suppli Ulrik (Denmark)

JMA Case Reports Session

JMA CR JMA Case Reports Session Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 9 (FIL)

Chairs Olympia Tsilochristou (United Kingdom) Alessandra Arcolaci (Italy)

Successful intravaginal graded human seminal plasma desensitization in a Can F5 sensitized patient Gemma Vilà-Nadal (United Kingdom)

Recurring anaphylaxis – a diagnostic and therapeutical challenge Márcio André Mesquita (Portugal)

Refractory chronic urticaria treated with omalizumab in a young adult with common variable immunodeficiency Pasquale Comberiati (Italy)

Immunological characterization of wilson disease Marcello Albanesi (Italy)

Which came first: The chicken, the quail or the egg? Cristiana Cancela Ferreira (Portugal)

An example of brilliant response to anti TNF treatment in refractory cardiac sarcoidosis Federico Delle Vedove (Italy)

Occupational contact urticaria caused by epoxy resins: A case report Diana Betancor (Spain)

A very unexpected cause of chronic urticaria Míriam Araújo (Portugal)

Chronic urticaria – what about montelukast? Míriam Araújo (Portugal)

Urticaria-angioedema paraneoplastic syndrome associated with renal cells carcinoma Ana Rodolfo (Portugal)

Allergy diagnosis and systems medicine > Food allergy > Basic Immunology > Precision Medicine

Late Breaking Poster Discussion Sessions (LB PDS) LB PDS 06 New trends in allergy diagnosis Tuesday, 4 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Robert Boyle (United Kingdom) Stephanie Dramburg (Germany)

Structure based epitope grafting indicates the IgE specific to the major birch pollen allergen, Bet v 1, binds a subset of potential epitopes in a patient specific manner Stefanie Schmalz (Austria)

PIPE-cloned recombinant human IgE, IgG1 and IgG4 antibodies against the major birch pollen allergen Bet v 1 in the PIPEline Verena Katarina Köhler (Austria)

Discovery and validation of a high-performance diagnostic test for peanut allergy Mayte Suarez-Farinas (United States)

Prevalence and Impact IgE to CCD using multiple markers in multiplex in vitro test Adriano Mari (Italy)

Longitudinal assessment of sensitization to grass pollen allergen molecules in a birth cohort – the importance of Phl p 4 for diagnosis and prediction of grass pollen allergy Marit Westman (Sweden)

Allergenicity assessment of pollens from seven Artemisia species Zhongshan Gao (China)

Molecular phenotyping of patients with different organ manifestations using single house dust mite allergens Uta Jappe (Germany)

House dust mite sensitization prevalence and IgE profiles in two different climatic zones Adriano Mari (Italy)

ENEA, a peach IgE-binding protein cross-reacting with the latex major allergen Hev b 5 Adriano Mari (Italy)

Evaluation of a highly sensitive ELISA for the determination of Tryptase in human serum samples Nadine Offermann (Germany)

Immunoglobulin levels in adult bronchiectasis: Do not forget to measure! Aysenaz Taskin (Turkey)

The tortuous path to diagnosis (Dx) of eosinophilic gastritis and eosinophilic gastroenteritis (EG/EGE) in the united states: A real-world, population-based study Mirna Chehade (United States)

Food allergy > Clinical Allergology > Pediatrics > Allergen immunotherapy

Oral Abstract Sessions (OAS)

OAS 21 Treatment of food allergy Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Kirsten Beyer (Germany) Jose Ferreira (Portugal)

Session roadmap Kirsten Beyer (Germany)

Extended daily dosing of AR101 for peanut allergy results in higher tolerated doses and continued immunomodulation Katharina Blümchen (Germany)

High rate of sustained unresponsiveness in peanut-allergic children undergoing oral immunotherapy using heat-modified peanut: Results from the BOPI study Nandinee Patel

Identifying allergic children with severe adverse events during oral peanut challenges in the LEAP studies by assessing basophil activation Alexandra F. Santos (United Kingdom)

The novel long-acting IgETrap-Fc fusion protein GI301 elicits therapeutic synergy in combination with probiotics for the treatment of food allergy Bo Gie Yang (South Korea)

Post desensitization strategy after successful oral immunotherapy to egg Giovanni Battista Pajno (Italy)

Pediatrics > Basic Allergology > Basic Immunology > Precision Medicine

Oral Abstract Sessions (OAS)

OAS 22 Immunopathogenesis of pediatric allergic diseases Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 10 (FIL)

Chairs Eva Untersmayr (Austria) Florentina Sava (United Kingdom)

Session roadmap Eva Untersmayr (Austria)

Breast milk fatty acid composition of allergic and non-allergic mothers: The ulm SPATZ health study Linda Siziba (Germany)

MiRNA and cytokines in breast milk may be associated with the development of allergic diseases in breast-fed infants Naohiro Itoh (Japan)

Serum periostin levels are associated with polysensitization and perinatal and postnatal factors in children Myongsoon Sung (South Korea)

The Dynamics Of Antimicrobial Peptide Expression In Pediatric Atopic Dermatitis Asya Kudryavtseva (Russia)

Correlation between intestinal barrier dysfunction and epigenetic activation of atopy in children with food hypersensitivity skin symptoms Olga Pakholchuk (Ukraine)

The role of gene polymorphisms and serum levels of growth factors in the immunopathogenesis of atopic diseases in children Olga Semernik (Russia)

Allergen immunotherapy > Precision Medicine > Food allergy > Basic Immunology Oral Abstract Sessions (OAS)

OAS 23 Novel approaches of allergen immunotherapy Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 11 (FIL)

Chairs Stephen R Durham (United Kingdom) Oliver Pfaar (Germany)

Session roadmap Stephen R Durham (United Kingdom)

A novel Pru p 3 sublingual immunotherapy ultra-rush protocol Ana Luísa Moura (Portugal)

Strong dose-response using a conjunctival provocation test during a phase II allergen immunotherapy study with subcutaneously administered tyrosine adsorbed modified grass allergen + MPL Pieter-Jan De Kam (United Kingdom)

Immunomodulatory properties of lolium perenne peptides for the treatment of seasonal allergic rhinitis Janice Anastasia Layhadi (United Kingdom)

Allergoids conjugated to mannan drive monocyte differentiation into tolerogenic dendritic cells and anti-inflammatory macrophages Cristina Benito Villalvilla (Spain)

A novel toll-like receptor 7 agonist can ameliorate phleum pratense induced allergic responses in vitro Max Kirtland (United Kingdom)

Dermatology > Clinical Immunology > Basic Immunology > Biologicals

Oral Abstract Sessions (OAS)

OAS 24 Atopic dermatitis from bench to bedside Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 12 (FIL)

Chairs Charlotte G. Mortz (Denmark) Luis Miguel Borrego (Portugal)

Session roadmap Charlotte G. Mortz (Denmark)

In vivo raman spectroscopy discriminates between filaggrin loss-of-function carriers vs. wild-type in day 1-3 neonates Jonathan O'B Hourihane (Ireland)

Eosinophil count, serum CCL17/18/26 and IgE levels in atopic dermatitis: Upadacitinib phase 2 study analysis Stephan Weidinger (Germany)

The importance of patch testing in drug reaction with eosinophilia and systemic symptoms 10 years after Francisca Jácome Morgado (Portugal)

Treatment satisfaction in patients receiving dupilumab for moderate-to-severe atopic dermatitis Amanda Lans (The Netherlands) Conjunctival inflammation and loss of goblet cells in atopic dermatitis patients treated with dupilumab in daily practice Daphne Suzanna Bakker (The Netherlands)

Polyprenol alone in atopic dermatitis management Ivans Sergejs Kuznecovs (Latvia)

Asthma > Basic Immunology

Poster Discussion Sessions (PDS)

PDS 20 Experimental studies in asthma Tuesday, 4 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Susanne Krauss-Etschmann (Germany) Milena Sokolowska (Switzerland)

Mild maternal smoking regulates gene expression in CD8 SP Thymic T cells in prenatally exposed murine offspring Barbara Hammer (Germany)

Distinct HDM (House Dust Mite) -mediated “asthma” phenotypes in 4 mouse strains - partly associated with differences in microbial populations detected in the lungs Barbara Hammer (Germany)

Development of a steroid-resistant asthma model in mice, and possible involvement of neutrophils in the pathogenesis Takeshi Nabe (Japan)

House dust mite stimulates CD93 expression in in vitro and in vivo allergic asthma model Eun-Yi Oh (South Korea)

The repeating of methacholine inhalation induced the airway inflammation and remodeling in murine model of asthma Shin Ohta (Japan)

Pharmacological inhibition of janus-activated kinases (JAK) leads to anti-inflammatory effects comparable to those obtained with an Anti-IL-5 antibody in a house dust mite-driven mouse model of asthma Anna Rita Pisano (Italy)

Combined Anti-IL-4 and Anti-IL-13 vaccination using kinoid technology prevents development of house dust mite-induced asthma in mice Laurent Lionel Reber (France)

Effects of tobacco smoking on the murine lung and gut microbiome Draginja Kovacevic (Germany)

Microarray analysis and mathematical modelling in equine asthma diagnostics Samuel J White (United Kingdom)

Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium Dong-Hyun Lee (South Korea)

Human and murine Th9 cells in allergic inflammation Stephanie Musiol (Germany)

The effect of repeated inhalation of bronchodilator in a murine model of asthma Megumi Jinno (Japan)

A murine model for exercise-induced bronchoconstriction in swimmers Tatjana Decaesteker (Belgium) Effect of 6-gingerol on CD4+ T-Helper (Th2) immune response and airway remodeling in mouse model of house dust mite (HDM)-induced asthma Babajide Oluwaseun Ajayi (Nigeria)

Probiotic microorganism lactobacillus reuteri impact on the prevalence of allergic asthma and atopic dermatitis in obese Slovenian children Lilijana Besednjak-Kocijancic (Slovenia)

Basic Immunology > Food allergy > Basic Allergology

Poster Discussion Sessions (PDS)

PDS 21 Mediators in anaphylaxis and angioedema Tuesday, 4 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Knut Brockow (Germany) Hans Jürgen Hoffmann (Denmark)

Effects of PI3K inhibitors on mediator release following IgE cross-linking of human lung and cord blood-derived mast cells Maria Ekoff (Sweden)

Tomosyn-1 is a gatekeeper of mast cell and basophil degranulation and is upregulated by high levels of IgE Joana Vitte (France, Metropolitan)

Mouse mast cell protease-6 induced aberrant vascular remodeling via monocyte chemotactic protein-1 in oxygen-induced retinopathy Kenshiro Matsuda (Japan)

Off-target occupation of the non-immune receptor MRGPRX2 as a novel endotype of immediate drug hypersensitivity: Additional insights from cultured human mast cells Jessy Elst (Belgium)

Impaired endothelial function in mastocytosis correlates with disease severity Roberta Parente (Italy)

ELKS controls mast cell degranulation by regulating the chromatin context of syntaxin 4 Hiu Yan Lam (Singapore)

The impact of serum anaphylactic factors and CCL2 on basophil migration in vitro Maruša Rihar (Slovenia)

MiR-155-5p, MiR-26-3p and MiR-29-5p/3p serum levels are decreased in human anaphylaxis Emilio Núñez-Borque (Spain)

Active transport of iron-flavonoid complexes by the major allergen Bet V 1 leads to enhanced activation of the aryl hydrocarbon receptor Franziska Roth-Walter (Austria)

Proteomic analysis of an in vitro endothelial system in response to serum of anaphylactic patients Javier Robles Sebastián (Spain)

Recurring anaphylaxis – a diagnostic and therapeutical challenge Márcio André Mesquita (Portugal)

Recombinant human C1 esterase inhibitor for the acute treatment of hereditary angioedema attacks: Multi-country, european registry analysis Andrea Zanichelli (Italy)

Rapid and nearly complete suppression of plasma kallikrein activity with the oral inhibitor KVD900: Results of a phase 1 study evaluating KVD900’s potential as a treatment for acute attacks of HAE Andreas Maetzel (Canada)

Autoimmune disorders associated with hereditary angioedema: Systematic literature review and findings from USA claims database Markus Magerl (Germany)

Necrotizing fasciitis as complication of palpebral angioedema to ibuprofen and atopic dermatitis Cristina Cuevas (Spain)

Environmental and occupational allergy

Poster Discussion Sessions (PDS)

PDS 22 Allergy and environmental health Tuesday, 4 June 2019

10:30-12:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Jeroen Titus Buters (Germany) Guy Scadding (United Kingdom)

Allergic sensitization profiles in immigrant population Francisca Vílchez Sánchez (Spain)

Prevalence of inhalant allergen sensitization in Dutch atopic children (0-18 yr) L. J. Landzaat (The Netherlands)

A new trend of cockroach sensitization : A cross-sectional observational study on indoor allergens and food allergens in the inland regions of Southwestern China Wu Zehong (China)

How to sample indoor allergens for exposure assessment - correlation between allergens in vacuumed surface samples and allergens on electrostatic dust collectors in day-care centers Ingrid Sander (Germany)

A deep learning approach for detecting the effects of indoor air pollutants concentrations on pulmonary functioning test results: Are asthma attacks predictable? SungChul Seo (South Korea)

Differentiation of birch pollen proteins and their subunits composition in relation to the air pollution level Dorota Myszkowska (Poland)

The protective effect of fluticasone propionate on urban particulate matter exposed human nasal fibroblasts Dong Chang Lee (South Korea)

Rhinitis and pollution Sofia Martins Farinha (Portugal)

Regional calendars and seasonal statistics for the United Kingdom’s main pollen allergens Carsten Ambelas Skjoth (United Kingdom)

Application of virtual-slide microscopy in aerobiology: A gateway to tele-aerobiology? Lukas Dirr (Austria)

Environmental risk factors for pediatric allergic rhinitis: Seongnam atopy project 2017 Cheongse Won (South Korea)

Epigenetic study of environmental heavy metals exposure in childhood asthma Lobna Abdelaziz El-Korashi (Egypt)

Association on blood heavy metal level with asthma, allergic rhinitis, atopic dermatitis, atopic multimorbidity, and lung function Dong Keon Yon (South Korea) Sister Society Symposia (SSS)

SSS 11 EAACI – JSA Joint Symposium: Establishment of precision medicine for allergic diseases Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 7 (Altice Arena)

Chairs Shigeharu Fujieda (Japan) Kenji Izuhara (Japan)

Development of biomarkers for precision medicine for allergic diseases Kenji Izuhara (Japan)

Establishment of precision medicine for asthma using its endotypes Hisako Matsumoto (Japan)

Novel treatment for intractable chronic rhinosinusitis with nasal polyp: Strategy for precision medicine Shigeharu Fujieda (Japan)

Asthma > Dermatology > Environmental and occupational allergy > Precision Medicine

Symposia (SYM)

SYM 27 Understanding the complexity of atopic disease through a systems biology approach Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 1 (Altice Arena)

Chairs Isabella Annesi-Maesano (France) Filipe Inácio (Portugal)

Link between asthma, hay fever and eczema Gerard Koppelman (The Netherlands)

Environment, epigenome and asthma Paul Lavender (United Kingdom)

Lessons learnt from 10 years of genome-wide association studies Michael A Portelli (United Kingdom)

Environmental and occupational allergy > Asthma > Clinical Allergology > Allergy diagnosis and systems medicine

Symposia (SYM)

SYM 28 Occupational allergy: New perspectives and challenges Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 2 (Altice Arena) Chairs Rodrigo Rodrigues Alves (Portugal) Joaquin Sastre (Spain)

New workplace hazards for occupational allergy and asthma Santiago Quirce (Spain)

How to handle patients with occupational respiratory symptoms? Jolanta Walusiak-Skorupa (Poland)

Occupational allergy: From research to daily practice Monika Raulf (Germany)

Food allergy > Basic Immunology > Clinical Allergology > Precision Medicine

Symposia (SYM)

SYM 29 Thinking beyond the usual food allergens Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 3 (Altice Arena)

Chairs Isabel Janet Skypala (United Kingdom) Jörg Kleine-Tebbe (Germany)

Thaumatin-like proteins (TLPs) Araceli Diaz Perales (Spain)

Oleosins and profilins Laurian Jongejan (The Netherlands)

Alpha-gal related meat allergy Tilo Biedermann (Germany)

Ocular Allergy > Clinical Allergology > Pediatrics

Symposia (SYM)

SYM 30 The eye in allergy: A tiny organ, a lot of problems Tuesday, 4 June 2019

10:30-12:00 hrs Room Hall 5 (Altice Arena)

Chairs Diana Margarida Silva (Portugal) Marek L Kowalski (Poland)

Allergy in the eye: Pathophysiologic key points Virginia Lysbeth Calder (United Kingdom)

Recognizing ocular allergy syndromes Jean-Luc Fauquert (France)

Immunomodulation in ocular allergy Andrea Leonardi (Italy) Asthma > Environmental and occupational allergy > Pediatrics > Clinical Allergology

Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 07 Management of respiratory disease Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 6 in e-Poster Area A (FIL)

Chairs Enrico Heffler (Italy) Gerard Koppelman (The Netherlands)

Forced oscillation technique as useful method to monitor the efficacy of mepolizumab in treating severe eosinophilic asthma Chiara Tontini (Italy)

Salbutamol and ipratropium bromide are high risk factors for atrial arrhythmias in patients with COPD and CVS diseases RAHUL SETHI (Armenia)

Salbutamol and ipratropium bromide are risk factors for arrhythmias in patients with CVS diseases RAHUL SETHI (Armenia)

Occupational asthma in patients exposed to Persulfate Salts. A three years experience (2016-2018) in an allergy department Leyre Baptista-Serna (Spain)

Occupational asthma and rhinitis due to formaldehyde Alba María Extremera Ortega (Spain)

Atopic status and exercise-induced bronchoconstriction in high-school elite athletes Janne Goossens (Belgium)

Diagnosis of occupational respiratory allergic diseases in bakers and their exposition to flour powders. Pietro Maculan (Italy)

Using an electronic nose to monitor airway dysfunction in elite swimmers: A pilot study João Cavaleiro Rufo (Portugal)

“Blockers” can benefit from 300IR house dust mite tablet - results of a large multicentre clinical trial in house dust mite induced allergic rhinitis patients Martine Le Gall (France)

“Blockers” can benefit from 300IR house dust mite tablet - results of a large multicentre clinical trial in house dust mite induced allergic rhinitis patients Peter Socrates Creticos (United States)

Food allergy > Drug allergy > Allergen immunotherapy

Late Breaking Thematic Poster Sessions (LB TPS)

LB TPS 08 Anaphylaxis Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 12 in e-Poster Area B (FIL)

Chairs Ozge Soyer (Turkey) Giovanni Battista Pajno (Italy) School board policies on prevention and management of anaphylaxis in Istanbul: Where do we stand? Sevgi Bilgiç Eltan (Turkey)

When adrenaline freezes over: Safety of epinephrine autoinjectors in the cold weather- a real-life pilot study Piotr Lacwik (Poland)

Parenteral knowledge of anaphylaxis and their performance in epinephrine auto-injector use: A survey in turkish patients Derya Ufuk Altintas (Turkey)

Epinephrine prescription in emergency department Óscar Marcelo González Jiménez (Spain)

Underdiagnosis of anaphylaxis in the County Emergency Clinical Hospital of Targu Mures: Misdiagnosed or miscoded? Beata Bodi (Romania)

Evaluation of the safety of administration of yellow fever vaccine in patients with history of egg anaphylaxis Cláudia França Cavalcante Valente (Brazil)

Safety and efficacy data of AK002, an anti-siglec-8 monoclonal antibody, in patients with indolent systemic mastocytosis (ISM): Results from a first-in-human, open-label phase 1 study Frank Siebenhaar (Germany)

Anaphylaxis due to occupational allergy to Locusta Migratoria and Schistocerca Gregaria Eva Ganseman (Belgium)

Idiopathic Anaphylaxis or Allergic reactions to Carmine (E120)?? Patricia Benito Martinez (Spain)

Food anaphylaxis to quinoa seed Catharina Chatain (France)

Manioc Anaphylaxis & Hevamine A: A new latex protein involved in latex- syndrome cross-reactivity Marta López San Martín

Recurrent acute urticaria as precursor of wheat dependent exercise-induced anaphylaxis Teresa Posadas-Miranda (Spain)

Case of anaphylactic shock to beer Manuel Morales Gavilán (Spain)

The healthy food paradox: Anaphylaxis to baobab Matteo Martini (Italy)

Glutaraldehyde modified allergen extract immunotherapy are able to cause anaphylaxis as an adverse reaction? Jonathan Kilimajer Astudillo (Spain)

A complete honeybee “venome”. Improving diagnostic and therapeutic tools Fernando Pineda de la Losa (Spain)

Latex immunotherapy: An exceptional improvement in quality of life Iolanda Alen Coutinho (Portugal)

Allergen immunotherapy > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 41 Immunotherapy IV Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 1 in e-Poster Area A (FIL) Chairs Ana Margarida Pereira (Portugal) Darío Antolín-Amérigo (Spain)

Pilot study to determine effect of feeding cat food made with egg product containing Anti- Fel D1 antibodies to cats on human allergy symptoms James D Wedner (United States)

Feeding Anti-Fel d1 chicken antibodies decreases active Fel d1 on cat hair Ebenezer Satyaraj (United States)

A novel patient-reported outcome (PRO) instrument assessing the side effects of peanut oral immunotherapy Kari Christine Nadeau (United States)

Evaluation of the efficacy and safety of sublingual immunotherapy (traditional coca’s extract) in the treatment of allergic rhinoconjunctivitis Reham Mohamed El Shabrawy Ali (Egypt)

Development and assessment of dietitian-led counselling program for oral immunotherapy Hélène Leroux (Canada)

Safety of a five-step versus a six-step ultra-rush venom immunotherapy protocol Ricardo Moço Coutinho (Portugal)

Specific inmunotherapy in adult patients sensitised to alternaria alternata Almudena Delgado González (Spain)

Comparison of the cost of illness during symptomatic treatment and specific immunotherapy, in patients with allergic asthma to mites: The itaca study David González De Olano (Spain)

Mid-scale processability and characterization of the allergoidization of salsola kali allergen extracts Anne Cossé (Germany)

Birch sap as a novel treatment for birch pollen allergy Ana Isabel Sancho (Denmark)

Efficacy of specific immunotherapy in fungal allergy Besim Prnjavorac (Bosnia and Herzegovina)

Subcutaneous immunotherapy with aeroalergens - evaluation of adhesion in real life Tatiana Lourenço (Portugal)

Immunotherapy with an allergen extract of candida albicans to prevent recurrent episodes of vulvovaginal candidiasis (RVVC) Luis Mario Tubella (Spain)

A rare complication of allergen-specific immunotherapy: Eczema herpeticum Fatma Merve Tepetam (Turkey)

Anti-allegic and anti-inflammatory effect of Hizikia fusiformis Ji-Eun Lee (South Korea)

RNA and DNA drugs based on prolonged acting liposomes Olesya O. Koloskova (Russia)

Feasibility of studying the changes in relative distribution of allergen specific antibody isotypes overtime David Obeso (Spain)

Allied health and primary care > Asthma > ENT > Allergy diagnosis and systems medicine

Thematic Poster Sessions (TPS)

TPS 42 Patient-centered management of allergic airways disease Tuesday, 4 June 2019 12:00-13:30 hrs Room e-Poster station 2 in e-Poster Area A (FIL)

Chairs Inger Kull (Sweden) Jose Ferreira (Portugal)

The role of health visitor in a demanding clinical protocol Maria V. Kritikou (Greece)

Care continuity for children with asthma- the willingness of primary caregivers I-Jen Wang Wang (Taiwan)

History of asthma and lung cancer risk: A population based cohort study I-Jen Wang Wang (Taiwan)

Occupational asthma in a floriculturist patient Catalina Gomez (Colombia)

From asthma to hypereosinophilic syndrome with cardiac involvement - a case report Raquel Viana (Portugal)

The relationship between viral infections and clinic in children hospitalized with the diagnosis of lower respiratory tract infection Emine Vezir (Turkey)

Mepolizumab for chronic eosinophilic pneumonia – maximizing its benefits Ana Luísa Fernandes (Portugal)

Perception of allergic rhinitis: Use of the brief illness perception questionnaire Pascal Maigret (France)

Chronic cough with skin rash as presenting symptoms of eosinophilic inflammation related with follicular variant peripheral T cell lymphoma Sang-Heon Kim (South Korea)

The beliefs about allergic rhinitis and its treatment options from people with and without allergic rhinitis in the central region of Thailand Sirada Patcharanarumol (Thailand)

A Retrospective Cohort Analysis Of The Effectiveness And Safety Of SCIT And SLIT. Clinical Presentations. Tatiana Surkova (Russia)

A two-site immunoassay for the quantification of lolium perenne grass pollen allergen, Lol P 1 Max Bermingham (United Kingdom)

The lived experience of nasal polyps – the current understanding of the patients’ perspective Robert Chan (United Kingdom)

Novel patient centric approach to understand the patient experience of nasal polyps Robert Chan (United Kingdom)

Eosinophilic otitis media in eosinophilic granulomatosis with polyangiitis: A single-center cohort Noeul Kang (South Korea)

Diagnostic value of salivary liquefied carbohydrate antigen KL-6 in children with pneumonia Huimin Huang (China)

Successful intravaginal graded human seminal plasma desensitization in a Can F5 sensitized patient Gemma Vilà-Nadal (United Kingdom)

Clinical Immunology > Biologicals > Basic Immunology > Drug allergy

Thematic Poster Sessions (TPS) TPS 43 Update on biologicals Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 3 in e-Poster Area A (FIL)

Chairs Apostolos Bossios (Sweden) Adam M Chaker (Germany)

The efficacy of omalizumab in severe pruritus associated to immune checkpoint inhibitor: First case report in Spain Olalla Verdeguer Segarra (Spain)

Importance of skin tests in the evaluation of hypersensitivity reactions to monoclonal antibodies Teodorikez Wilfox Jimenez-Rodriguez (Spain)

Assessment and prediction of cetuximab-induced hypersensitivity reactions using specific IgE detection kyungchul kim (South Korea)

IL-5-modulating agents are an effective novel therapy for severe and life-threatening eosinophilic disorders ODED SHAMRIZ (Israel)

Three specific monoclonal antibodies bound to the major birch allergen Bet V 1 are sufficient to block IgE-mediated allergic response Matthew C. Franklin (United States)

Management problems in severe chronic inducible urticaria: 2 case reports Roxana silvia Bumbacea (Romania)

Efficacy of omalizumab in hereditary alpha tryptasaemia Chris Rutkowski (United Kingdom)

Efficacy and safety of omalizumab for severe Japanese cedar pollinosis in patients treated with combination oral and nasal corticosteroids Mitsuhiro Okano (Japan)

Effect of omalizumab in peripheral T cell subpopulations in chronic urticaria Cristina Alejandra López Rodriguez (Spain)

A real life experience of omalizumab: Nine-year follow-up of 205 patients in a single center sengül beyaz (Turkey)

Anti-eosinophil therapy is associated with decreased body mass index in severe asthmatics: A retrospective analysis Merin E Kuruvilla (United States)

Patients with severe eosinophilic asthma treated with mepolizumab: A 12-month follow-up from our clinical practice Irene Hernández-Martín (Spain)

Mepolizumab - a reference center experience Catarina Pereira Coutinho (Portugal)

Ophthalmological characteristics and treatment outcomes of conjunctivitis in patients receiving dupilumab for moderate-to-severe atopic dermatitis Amanda Lans (The Netherlands)

In atopic dermatitis patients, dupilumab therapy reveals that IgE against food allergens decrease faster than IgE specific for respiratory allergens POL ANDRE APOIL (France)

Cell-penetrating peptide dendrimers as multifunctional therapeutic agents Ksenia Kozhikhova (Russia)

An example of brilliant response to anti TNF treatment in refractory cardiac sarcoidosis Federico Delle Vedove (Italy)

Asthma > Clinical Allergology Thematic Poster Sessions (TPS)

TPS 44 Epidemiology and risk factos Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 4 in e-Poster Area A (FIL)

Chairs Martina Vasakova (Czech Republic) Berber Vlieg-Boerstra (The Netherlands)

International severe asthma registry (ISAR): Mission statement Giorgio Walter Canonica (Italy)

Heterogeneity of childhood asthma in Korea: Cluster analysis of children with asthma from Korean childhood asthma study (KAS) Jinho Yu (South Korea)

Association between male and female body mass index with lung function parameters in asthma Marina Lampalo (Croatia)

Senzitizer-induced occupational asthma in traditional and industrial bakers Jordan Minov (Macedonia, Former Yugoslav Republic of)

Comorbidities and asthma severity in a brazilian cohort of patients Luane Marques Mello (Brazil)

Prevalence and clinical characteristics of asthma in children 6-7 and 13-14 years old from Luanda, Angola Margarete Lopes Teixeira Arrais (Angola)

The association of age of puberty onset and adulthood lung function is mediated by height growth rate in adolescence and its induced DNA methylation in young adulthood Hongmei Zhang (United States)

Prevalence and risk factors in bronchial asthma in children of 6-7 years old and adolescents of 13-14 years old in the municipality of Puerto Vallarta, Mexico María Angeles Juan Pineda (Mexico)

Lung function decline in elderly asthma: 3-year follow up in prospective study Kyoung-Hee Sohn (South Korea)

Asthma hospitalizations – what changed in the last decade? Inês Gonçalves Nunes (Portugal)

Causes behind admission to pediatric intensive care unit (PICU) in asthmatic patients in Qatar Mehdi Adeli (Qatar)

Inhaled corticosteroids are associated with increased pneumonia risk in asthma patients Young-Joo Cho (South Korea)

Age and obesity are associated with increased asthma severity in algerian patients with allergic asthma sara Benazzouz (Algeria)

Factors related to treatment response in cough variant asthma Aleksandra Rybka (Poland)

Exacerbations in patients with severe asthma Alberto García de la Fuente (Spain)

Correlation of serum vitamin D level and asthma control: A cross-sectional study from Jeddah, Saudi Arabia Majdy M. Qutub (Saudi Arabia)

Longitudinal study of risk factors for asthma exacerbations in Chinese schoolchildren Ting Fan Leung (Hong Kong SAR) Drug allergy > Allergy diagnosis and systems medicine

Thematic Poster Sessions (TPS)

TPS 45 Drug hypersensitivity: Epidemiology, mechanisms and diagnostics Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 5 in e-Poster Area A (FIL)

Chairs Eva Gomes (Portugal) Ibon Eguiluz-Gracia (Spain)

Severe cutaneous adverse reactions to drugs in latin america: An update of racgrad study Dolly V Rojas (Colombia)

Development and validation of questionnaire for study of drug allergy among armenian population Zaruhi Gevorg Kalikyan (Armenia)

Adverse drug events and drug hypersensitivity reactions leading to emergency department visits: An observational study in four university hospitals Sang-Heon Kim (South Korea)

Knowledge and attitudes regarding drug allergy among residents and interns in tracia region of turkey; a multicenter study Burçin Beken (Turkey)

The last 12 years of a contrast media allergy consultation Maria Inês Silva (Portugal)

True penicillin allergy in internal medicine hospitalized patients Bárbara Kong Cardoso (Portugal)

Drug hypersensitivity reactions to cephalosporins Bárbara Kong Cardoso (Portugal)

Biotin labeled clavulanic acid to deepen analysis of serum proteins target of haptenation: Implication in betalactams allergy studies Adriana Ariza Veguillas (Spain)

Myeloid dendritic cells and monocyte-derived dendritic cells exhibit a different maturation pattern in patients with immediate allergic reactions to betalactams Alba Rodriguez Nogales (Spain)

Positive drug provocation test to amoxicillin in patients with negative skin test María Salas Cassinello (Spain)

Drug provocation tests with Beta-Lactams and re-exposure rate Mariana Lobato (Portugal)

Positive skin test with clavulanic acid – our experience Cosmin Boteanu (Spain)

Allergy tests in pregnant women with syphilis and history of penicillin allergy in Brazil Albertina Varandas Capelo (Brazil)

Basophil activation test (BAT) is a useful tool for the diagnosis of drug allergy: A case report Marianna Tziotou (Greece)

Beyond the antimicrobial sulfamides Jennifer Jose Compadre (Spain)

Hypersensitivity to multiple corticosteroids: A challenging work-up Míriam Araújo (Portugal) Drug allergy > Biologicals

Thematic Poster Sessions (TPS)

TPS 46 Management of drug hypersensitivity Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 7 in e-Poster Area B (FIL)

Chairs Joana Sa Caiado (Portugal) Josefina Maria Rodrigues Cernadas (Portugal)

Meloxicam could be administered safely in two equal doses, during open oral challenge in patients with nonsteroidal antinflamatory drugs hipersensitivity Carlos Serrano (Colombia)

Anaphylaxis after successful desensitization to glatilamer acetate Leah Landaveri Sanchez (Spain)

Successful desensitization of a patient with IgE-mediated anaphylactic reaction to FVIII/VWF concentrate Burçin Beken (Turkey)

Evaluation of safety and tolerance of desensitization to platin salts and taxanes Cristiana Cancela Ferreira (Portugal)

Successful desensitization to oxaliplatin using omalizumab: A case report Joan Penella Mas (Spain)

Failure of adjuvant omalizumab in drug desensitization Cristina Cuevas (Spain)

Successful high risk oxaliplatin desensitization using omalizumab Leticia De las Vecillas Sánchez (Spain)

Safety and efficacy of desensitization to the platinum-containing compounds Teodorikez Wilfox Jimenez-Rodriguez (Spain)

Rapid drug desensitization for platinum-based chemotherapy drugs significantly increases peripheral blood IL-10 levels Ozdemir Can Tüzer (Turkey)

Desensitization of intravenous cyclosporine induced anaphylaxis Myung Shin Kim (South Korea)

Drug allergy in hematologic patient: Diagnosis and desensitization Attilio Di Girolamo (Italy)

Rituximab-induced serum sickness disease in a patient who was desensitized for rituximab induced severe urticaria Emine Vezir (Turkey)

Rituximab desensitization with two different protocols in two cases Ilknur Kulhas Celik (Turkey)

Successful desensitization protocol to intravenous brentuximab vedotin Maria Tsami (Greece)

Anaphylaxis and desensitization to RAMUCIRUMAB: About a first case Princy Beriziky (France)

Successful desensitization with panitumumab; a case report selver seda mersin (Turkey)

Successful desensitisation with alemtuzumab in a relaps remitting multiple sclerosis case Ceyda Tunakan Dalgiç (Turkey) Successful desensitization in a patient with methimazole induced serum sickness disease Selda Ali (Romania)

Successful rapid push subcutaneous desensitization in a patient with delayed local hypersensitivity reactions to immunoglobulins Rohit Rajiv Ghurye (United Kingdom)

Drug allergy > Clinical Allergology > Dermatology

Thematic Poster Sessions (TPS)

TPS 47 Different aspects on drug hypersensitivity Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 8 in e-Poster Area B (FIL)

Chairs Luciana Kase Tanno (Brazil) Teresa Gomes Moscoso (Portugal)

Sensitization to mepivacaine in a 10 years old patient Cristina González-Colino (Spain)

Generalized paralysis induced by local lidocaine injection Minkyoung Cha (South Korea)

Acute urticaria due to a vasoprotective drug Antonio Moreno-Fernandez (Spain)

Allergy to titanium - paradoxes in dentistry Lyudmila Leonidovna Lazarenko (Russia)

The “red man syndrome” followed by vancomycin-induced leukocytoclastic vasculitis Mehmet Avni Hoxha (Albania)

Erythropoietin allergy in a patient on hemodialysis Iuliana Badiu (Italy)

Dextromethorphan allergy Shuayb Elkhalifa (United Kingdom)

Sialadenitis induced by iodinated contrast: “Iodide mumps” Javier Iglesias-Souto (Spain)

The multiple faces of dimethyl fumarate (tecfidera) drug hypersensitivity Agne Ramonaite (Lithuania)

Photo-induced telangiectasia: An uncommon dermatological side-effect to many drugs Mario Vaccaro (Italy)

Ondansetron: Friend or foe? Sara Patrícia Carvalho (Portugal)

Hypersensitivity to antituberculosis drugs in patients with pulmonary tuberculosis Sergii Zaikov (Ukraine)

First line antituberculosis drug hypersensitivity: Culprit two drugs Metin Keren (Turkey)

A rare case of drug allergy; multi-drug resistant tuberculosis Tugçe Yakut (Turkey)

Vaccine-induced hypersensitivity: What’s the value of skin tests ? Haifa Ben Romdhane (Tunisia) Allergic reaction to yellow fever vaccine in a patient with bird-egg syndrome Viviane Steiner-Monard (Switzerland)

Paclitaxel induced vulgaris in a patient with ballon angioplasty Selda Ali (Romania)

Gentamicin allergy – a case report Ludmila Dvorakova (Czech Republic)

Dermatology > Pediatrics > Clinical Immunology > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 48 Angioedema and mastocytosis Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 9 in e-Poster Area B (FIL)

Chairs Clive Grattan (United Kingdom) Marta Ferreira Neto (Portugal)

The need for individually tailored prophylaxis with C1-INH concentrate in pediatric patients with hereditary angioedema (HAE) – real life data Inmaculada Martinez Saguer (Germany)

Long-term prophylaxis with RC1inh in pregnancy in HAE-NC1 INH inh patient Vesna Grivcheva-Panovska (Macedonia, Former Yugoslav Republic of)

Hereditary angioedema due to C1-INH: Case report Etleva Qirko Loloci (Albania)

Hereditary angioedema: 24 cases Ana lainez nuez (Spain)

Efficacy and safety outcomes for switching to lanadelumab from prior LTP: Findings from an interim analysis of the HELP OLE study Markus Magerl (Germany)

Angioedema’s clinical presentation and approach on an emergency department isabel silva (Portugal)

An algorithm for diagnosis of hereditary angioedema with normal C1-inhibitor: Applying molecular approach to clinical practice Marina Mendonça Dias (Brazil)

Burden of hereditary angioedema: Findings from a multinational patient survey in EU, Canada, and Australia Joan Mendivil (Switzerland)

Epidemiological study for type I/II hereditary angioedema disease through a novel dry blood spot (DBS)-based methodology Claudia Cozma (Germany)

Determinant factors of disease activity in hereditary angioedema due to C1 inhibitor deficiency Elsa Phillips-Angles (Spain)

Mutational spectrum of the SERPING1 gene in a population from southern spanish with hereditary angioedema due to C1 inhibitor deficiency Teresa De Aramburu Mera (Spain)

Effectiveness of long-term use of danazol in hereditary angioedema: 10 years follow-up at single service in brazil Fernanda Gontijo Minafra Silveira Santos (Brazil)

Rare forms of angioedema in Bulgaria: Experience since 1972. Past and present Anna Valerieva (Bulgaria)

Hereditary angioedema in a single family with specific mutations in both the plasminogen and SERPING1 genes Undine Lippert (Germany)

Hereditary angioedema with gastric expression – atypical presentation Rita Brás (Portugal)

Systemic mastocytosis (MS) – a deadly case Joana Queirós Gomes (Portugal)

Fracture risk reduction by bisphosphonates in mastocytosis Merel C. Onnes (The Netherlands)

Pulmonary and cardiovascular symptoms in patients with mastocytosis Marlena Magdalena Sztormowska (Poland)

Coexistence of mastocytosis in the skin with vitiligo (fortuity or coincidence?): A russian center case series Polina Pyatilova (Russia)

Ocular Allergy > Drug allergy > Dermatology

Thematic Poster Sessions (TPS)

TPS 49 Drug allergy, testing and miscellaneous Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 10 in e-Poster Area B (FIL)

Chairs Marina Atanaskovic-Markovic (Serbia) Marcelo Vivolo Aun (Brazil)

Basophil activation testing is useful in children allergic to neuromuscular blocking agents Tina Vesel Tajnšek (Slovenia)

Drug allergy in children – a referral to pediatric allergy consultation Joana Figueirinha (Portugal)

Drug induced enterocolitis syndrome (DIES): A clinical entity which deserves more awareness Anders VAn Thuijl (The Netherlands)

Hypersensitivity to analgesic/non-steroidal anti-inflammatory drugs: A retrospective study in a pediatric cohort Joana Moreno Cosme (Portugal)

Systemic mastocytosis in a 5 year old child presenting with hypovolemic shock, succeeded by severe anaphylaxis to fentanyl Inger Fa Bocca-Tjeertes (The Netherlands)

A six months old female infant with : A case report Marina Rigoni Costa Moreira (Brazil)

When the sun is no fun: Solar-induced? Angioedema in pediatrics Amiirah Aujnarain (Canada)

Features of the clinical course of atopic dermatitis related to the types of breeds of microorganisms in young children Olga Pakholchuk (Ukraine)

Laronidase hypersensitivity and desensitization in tipe I mucopolysaccharidosis: A case report JOSE ANTONIO GIL (Spain)

The current state of infant skincare methods at obstetrics departments and maternity hospitals Hiromi Uehara (Japan)

Chronic urticaria: A spanish pediatric cohort Catalina Bover Bauza (Spain)

The importance of measuring the concentration of nitrous oxide in exhaled air for epidemiological phenotyping of asthma in children Grzegorz Marek Brozek (Poland)

Allergy to chironomid larvae in a child owing an exotic pet Nerea Marchán Pinedo (Spain)

Internet use habits of parents having children with allergic diseases Ilknur Kulhas Celik (Turkey)

Pediatrics > Food allergy

Thematic Poster Sessions (TPS)

TPS 50 Food allergy in childhood Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 11 in e-Poster Area B (FIL)

Chairs Helen A Brough (United Kingdom) Kate Grimshaw (United Kingdom)

Incidence, triggers, symptoms and treatment of anaphylaxis in a pediatric hospital in São Paulo, Brazil Fabiana Andrade Nunes (Brazil)

Regional audit of paediatric anaphylaxis management in the midlands: Are we following national guidance? Amrit Dhesi (United Kingdom)

Allergen sensitization pattern of children with allergic diseases: Single center experience Ilknur Kulhas Celik (Turkey)

Transition of children with significant allergies and complex special needs- our experience Aparna Dr Kaniti (United Kingdom)

Prevalence of IgE sensitization to food and respiratory allergens in children Marina Snovskaya (Russia)

Evaluation of clinical symptoms and clinical course in pediatric patients with tree nut allergy Ilknur Kulhas Celik (Turkey)

The prevalence of systemic reactions and their sensitization profiles in children with pollen food syndrome Tetiana Umanets (Ukraine)

The natural history of egg allergy and factors associated with prognosis Ilknur Kulhas Celik (Turkey)

Bird-egg syndrome in pediatric age: Two cases report Ana Prieto-del Prado (Spain)

Fecal calprotectin as a biomarker of IgE-mediated food allergy in children with atopic dermatitis Alen Švigir (Croatia)

Serum vitamin D levels in food allergy patients are lower than those in healthy children Fumiya Yamaide (Japan)

Eosinophilic gastroenteritis found by pica during oral immunotherapy: A case report Koji Nishimura (Japan) Asthma > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 51 Asthma in the clinic Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 13 in e-Poster Area C (FIL)

Chairs Mark Larché (Canada) Magna Alves-Correia (Portugal)

Severity of allergic asthma associated with sensitization to food allergens Raisa Borges Castro (Brazil)

Clinical and immunological evaluation of cat-allergic asthmatics living with or without a cat Erik R Wambre (United States)

Analysis of fungal allergen and aspergillus fumigatus component sensitization in patients with respiratory diseases in southern China Luo Wenting (China)

Differences in clinical characteristics between aspergillus fumigatus sensitized asthmatics and allergic bronchopulmonary aspergillosis Haisheng Hu (China)

Immunological markers of secondary immune deficiency in patients with bronchial asthma Ella Vitalievna Churyukina (Russia)

Predictors of chronic lung disease in patients with common variable immunodeficiency Albertina Varandas Capelo (Brazil)

Periostin in serum and nasal material from patients with severe asthma of different age Andrei Kamaev (Russia)

Type 2 inflammation in severe persistent asthma under subtropical climate conditions Ruperto González-Pérez (Spain)

Vitamin D does not affect asthma development in real practice in Korean, one of temperate zones Byoung Whui Choi (South Korea)

Risk factors for reduced lung function after first wheezing episode: 7-year follow-up Ida Strengell (Finland)

Lost in the transition from paediatric to adult care? Experiences of young adults with severe asthma Maria Ödling (Sweden)

Influence of the severity of asthma and disease control on the placentofetal blood flow olga titova (Russia)

Fertility treatment among asthmatic women with live births – associated with perennial allergy? Casper Tidemandsen (Denmark)

An Online Survey Detected Specialty Specific Knowledge Gaps In The Maintenance Asthma Treatment Among Allergists, Chest Physicians, ENTs And Primary Care Désirée Erlinda Sophia Larenas-Linnemann (Mexico)

Inheritance patterns and the risk for asthma Dorina Qerimi (Albania)

Evaluation of systemic production of nitric oxide and metalloproteinase-9 in algerian patients with allergic asthma during stable and exacerbation statue sara Benazzouz (Algeria) Pediatrics > Asthma > ENT > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 52 Bronchitis, early wheeze and molecular allergy Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 14 in e-Poster Area C (FIL)

Chairs Philippe Eigenmann (Switzerland) Susanne Halken (Denmark)

The perinatal risk factors of acute bronchiolitis before one years old Po-Sung Chen (Taiwan)

Three cases of pediatric diffuse panbronchiolitis: A disease difficult to distinguish from asthma Satoshi Fujita (Japan)

Posttransplant bronchiolitis obliterans syndrome in children Dilara Fatma Kocacik Uygun (Turkey)

State of immunity in persistent asthma and bronchiolitis obliterans in children Ilgar Almas Mustafayev (Azerbaijan)

Bronchial asthma in pre-school children: A population-based cross-sectional study in Altai region Natalia Shakhova (Russia)

Serum periostin as a biomarker for the diagnosis of asthma in preschool children Natalia Shakhova (Russia)

Evaluation of hospitalization predictions of asthma scores in preschool children with acute asthma Emine Vezir (Turkey)

Factors related to wheezing in toddlers in a primary health care center of a tropical city in Mexico Désirée Erlinda Sophia Larenas-Linnemann (Mexico)

Risk factors for asthma outcomes of wheezing in early life Chuanhe Liu (China)

Orally administered immunostimulants as a prevention of asthma exacerbation and wheezing in children - a systematic review Jakub Zólkiewicz (Poland)

Strong association of serum EDN and sensitization status detected by an allergen microarray, ImmunoCAP ISAC, in preschool children with recurrent wheeze Mizuho Nagao (Japan)

Physicians’ perspective on preschool wheeze – an international survey (2nd stage) Aleksander Adamiec (Poland)

The effect of breastfeeding on the risk of asthma at school age Valentina Cvejoska-Cholakovska (Macedonia, Former Yugoslav Republic of)

Tree pollen in children with respiratory allergies in a single hospital in Busan Sung Won Kim (South Korea)

Patterns of molecular sensitization in children and adolescents in Dnipro region (Ukraine) Kateryna Gashynova (Ukraine)

Basic Immunology > Clinical Immunology

Thematic Poster Sessions (TPS) TPS 53 Infections: Pathogenesis and treatment Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 15 in e-Poster Area C (FIL)

Chairs Madeleine Radinger (Sweden) Guy Scadding (United Kingdom)

Dendrimeric peptide LTP exhibits potent antiviral properties against respiratory syncytial virus Igor Petrovich Shilovskiy (Russia)

Effectiveness of MP-AzeFlu in patients with different allergic rhinitis phenotypes: A german, multicenter, prospective study Ludger Klimek (Germany)

Functional activity of blood phagocytes in response to methicillin-resistant strains of staphylococcus aureus Sergey Yurievich Tereshchenko (Russia)

Comparative analysis of sequenced mycobacterium tuberculosis DNA genomes with different drug resistance spectra Irada Mirsaab Akhundova (Azerbaijan)

Parasitic hyperinfection Lorena Soto-Retes (Spain)

Eczematous reaction in scabies-when to treat? Anca C Chiriac (Romania)

A case of resolution of melkersson-rosenthal following a dental treatment Safi Zaidi (Canada)

Evaluation of the sensitization profile in patients with chronic allergic persistent rhinitis complicated by relapsing herpes simplex virus type 1 Galyna Nazarenko (Ukraine)

The effect of mycoplazma pneumoniae on the clinical course of bronchiolitis in children Gulzar Rafig Aliyeva (Azerbaijan)

Bacterial agonists of innate immunity LPS regulates spontaneous and induced production of alfa defensins of human neutrophils in vitro Svetlana Guryanova (Russia)

Broad spectrum of autoantibodies in a malaria infected patient: Are they harmful or protective for an infected host? Maja Stojanovic (Serbia)

Dietary intervention with a BbC50 fermentation product promotes the adaptive immune response in a murine influenza vaccination model Veronica Ayechu Muruzabal (The Netherlands)

Peripheral blood neutrophil and monocyte activation test for the differential diagnosis of bacterial versus viral etiology of acute intestinal infections Andrei Hancharou (Belarus)

Expression of immune system genes in patients with meningococcemia Lawrence DuBuske (United States)

Food allergy > Pediatrics

Thematic Poster Sessions (TPS)

TPS 54 Treatment of food allergy Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 16 in e-Poster Area C (FIL)

Chairs Paul J Turner (United Kingdom) Araceli Diaz Perales (Spain)

Does oit protocol for milk allergy really change dietetic patterns? Alice Toniolo (Italy)

Oral immunotherapy (OIT): Efficacy and safety in a group of children with cow’s milk allergy Dimitrios Petrakis (Greece)

Single-centre investigation of appropriate maintenance dose in rush oral immunotherapy for severe milk allergy Yuri Takaoka (Japan)

A phase 2 randomized controlled study using omalizumab as an adjunct therapy during multi-allergen oral immunotherapy in food allergic individuals to test long-term outcomes R. Sharon Chinthrajah (United States)

Real-life efficacy of omalizumab in children with severe allergy to multiple foods Stefania Arasi (Italy)

Oral immunotherapy for 7 patients with sesame allergy Takasato Yoshihiro (Japan)

Safety and efficacy of sesame oral immunotherapy LIAT NACHSHON (Israel)

Impact of epicutaneous immunotherapy (EPIT) for the treatment of peanut allergy in children and young adults: Follow-up from the consortium for food allergy research (CoFAR) study Stacie M Jones (United States)

AppleCare – birch pollen immunotherapy by consumption of Norbert Reider (Austria)

Nutritional evaluation of patients with successful oral immunotherapy: A strongly recommended procedure Bruna Pultrini Aquilante (Brazil)

Safety outcomes and differences in eliciting dose upon repeat oral food challenges in multi-food allergic individuals R. Sharon Chinthrajah (United States)

Cow´s milk desensitization in a 23-year-old man Melina Tejero Alcalde (Spain)

The effect of probiotic supplementation on the acquisition of tolerance to cows’ milk protein allergy Viktorija Kaminskaite (United Kingdom)

Predicting reactions to cow’s milk according to specific IgE values in sensitized patients Cristiana Lucia Solorzano Zepeda (Spain)

Contribution of molecular diagnosis in the prognosis of egg tolerance acquisition Sara Patrícia Carvalho (Portugal)

Long-term clinical course of rush oral immunotherapy in patients with severe wheat and hen’s egg allergy at a single center Junko Kumon

Long-term improvement of dietary life and burden after rush oral immunotherapy Komei Ito (Japan)

Long-term outcome of oral immunotherapy for food allergy Miyuki Hoshi (Japan)

Impact of a food allergy educational training to improve food allergy knowledge and management in the university food services staff Gabriela Tavares (Portugal) Food allergy > Pediatrics > Clinical Immunology

Thematic Poster Sessions (TPS)

TPS 55 Gastrointestinal immunology and EoE Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 17 in e-Poster Area C (FIL)

Chairs Simona Barni (Italy) Antonella Cianferoni (United States)

Novel peripheral blood allergen stimulation test for non-IgE-mediated gastrointestinal food allergies in neonates and infants Hisako Yagi (Japan)

Altered intestinal permeability in patients with LTP allergy Cristina Isabel Stein Coronado (Spain)

Clinical course of patients with allergic proctocolitis and enterocolitis Nevin Uzuner (Turkey)

Frequency of ??allergy and congenital immunodeficiency in children with colonic lymph nodular hyperplasia mahnaz sadeghi-shabestari (Iran)

Eosinophilic esophagitis: Clinical manifestations, allergic sensitizations and outcomes Blanca Andrés-López (Spain)

Eosinophilic esophagitis, rhinitis and occupational asthma caused by cereal flour allergy Manuel Barceló Ivars (Spain)

An eosinophilic esophagitis case mimicking cough variant asthma Emine Vezir (Turkey)

Eosinophilic esophagitis: A new component of the atopic march? Raquel Pitchon (Brazil)

A case of food-protein-induced enterocolitis syndrome (FPIES) with japanese clams and the lymphocyte proliferative response (LPR) with clam scratch test solution Kazuyo Kuzume (Japan)

Food protein induced enterocolitis syndrome (FPIES): A french cohort of 68 patients Anne-Sophie Colas (France)

The diagnostic value of in vitro food allergen-specific IgE in children with clinical history of food-induced allergic symptoms Ju Lee (Taiwan)

Description of 1,002 oral food challenges performed in a pediatric allergy unit Beatriz Moya Camacho (Spain)

Wheat-dependent anaphylaxis induced by exercise and stress. Case report Olga Naumova (Ukraine)

Asymptomatic sensitization to nuts in children with eczema: Estimation of risk of clinical reactivity Theodora Dimaresi (Greece)

Evaluation of correlation between LTP’s sensitization patterns and severity of anaphylaxis Ramon Lopez-Salgueiro (Spain)

Gluten fermentation with selected lactic acid bacteria strains induces its proteolysis and decreases its antigenicity Kamel Eddine El Mecherfi (Algeria) Effect of the specific IgE level on the eliciting dose in patients with cow’s milk allergy evaluated by a positive oral food challenge Tatsuki Fukuie (Japan)

Sensitization to molds through the digestive tract: A case report SARA ANAYA (Spain)

Profile of 15 patients with food dependent exercise induced anaphylaxis from India Karthik Nagaraju (India)

Food allergy > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 56 Case reports in food allergy and food-induced anaphylaxis Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 19 in e-Poster Area D (FIL)

Chairs Isabel Janet Skypala (United Kingdom) Barbara Bohle (Austria)

A case of systemic allergy to quorn Susan Tadros (United Kingdom)

Food allergy to cassava without latex sensitization Maud Deschampheleire (Belgium)

Occupational allergy to barnacle Marta Bernaola (Spain)

Serious coconut allergy in thai patient: Induction of oral tolerance Mónica González Afonso (Spain)

Banana hypersensitivity in Thailand: Case series Ratchataporn Thongkhom (Thailand)

Anaphylaxis due to and lychee in a patient sensitized to artemisia vulgaris Virginia Cabrera Hernández (Spain)

Edible insects: Investigation of cross-reactivity and reduction of allergenicity Erika Jensen-Jarolim (Austria)

What regulatory framework governs food allergy management in Lebanon? Fatima Youness (Lebanon)

Anaphylaxis to mushrooms (agaricus bisporus): A case report Inês Machado Cunha (Portugal)

Mushroom allergy: A case series Oyindamola Stephanie Kayode (United Kingdom)

Anaphylaxis due to oat milk Javier Iglesias-Souto (Spain)

Allergy to oat milk Tamara Fernández Teruel (Spain)

Cow´s milk allergy in adulthood Isabel Rezende (Portugal)

Allergy to chicken meat and chicken meat-dependent exercise-induced anaphylaxis: Case series VERAH HARPER (United Kingdom) Cat-pork syndrome: A rare condition Inês Falcão Fernandes (Portugal)

Oral mite anaphylaxis; a case series from an irish centre Jennifer Mulhall (Ireland)

Case of anaphylaxis due to pumpkin soup ingestion Juan Carlos Sainz (Spain)

Food-induced anaphylaxis as clinical form of pollen-food syndrome associated with recent onset seasonal allergic rhinitis due to ambrosia pollen sensitization. Case report Poliana Mihaela Leru (Romania)

Anaphylaxis to beluga caviar Sébastien Lefevre (France)

Clinical Immunology > Pediatrics

Thematic Poster Sessions (TPS)

TPS 57 Primary immunodeficiencies Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 20 in e-Poster Area D (FIL)

Chairs Isabella Quinti (Italy) Nicole Pinto (Portugal)

C4 deficiency and familial inheritance Nicolae Ovidiu Berghi (Romania)

Late-onset combined immunodeficiency: A case report Chiara Gelardi (Italy)

A strange case of CVID-associated granulomatous disease Chiara Gelardi (Italy)

Clinical presentation of granulomatous lymphocytic intersticial lung disease (GLILD) in a referral center in brazil Fernanda Gontijo Minafra Silveira Santos (Brazil)

Is the incidence of gastric tumor increasing in variable common immunodeficiency patients? Octavio Grecco (Brazil)

LRBA deficiency in three patients, single center experience Sara Sebnem Kilic (Turkey)

Two cases with homozygous TACI mutation; could TACI mutation be a cause of microcephaly and growth retardation? Sara Sebnem Kilic (Turkey)

Primary hemophagocytic syndrome: Description of new mutation in a patient at a referral center in brazil Fernanda Gontijo Minafra Silveira Santos (Brazil)

Refractory chronic urticaria treated with omalizumab in a young adult with common variable immunodeficiency Pasquale Comberiati (Italy)

Amyloidosis in patients with common variable immunodeficiency: A rare event associated with severe outcome Fevzi Demirel (Turkey)

Chronic granulomatous disease in a patient with rhodococcus equi in palmas-TO-brazil. Case report Raquel Prudente De Carvalho Baldaçara (Brazil) The expediency of combined immune-rehabilitation in the treatment of primary immunodeficiency in humoral type Lyudmila P Sizyakina (Russia)

Cerebral ischemic attacks in ADA2 deficiency treated with adalimumab Sara Sebnem Kilic (Turkey)

Autoimmune and inflammatory diseases in primary immune deficiencies Sara Sebnem Kilic (Turkey)

Two rare cases in one patient Sevan Iritsyan (Armenia)

Allergy diagnosis and systems medicine > ENT > Asthma > Clinical Allergology

Thematic Poster Sessions (TPS)

TPS 58 Molecular profile and allergy epidemiology Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 21 in e-Poster Area D (FIL)

Chairs Stephanie Dramburg (Germany) Ana Todo-Bom (Portugal)

Pattern of sensitization to common aeroallergens in the north of portugal: Four-year evaluation of an allergy center of a university hospital Maria João Vasconcelos (Portugal)

Current sensitization profile of allergic patients in Southern Slovakia - analysis of 6726 patients from one outpatient clinic Radovan Košturiak (Slovakia)

Ragweed pollinosis epidemy in Bratislava, Slovakia Martin Hrubisko (Slovakia)

Prevalence of sensitization to indoor allergens and its major components in Lithuania Linas Griguola (Lithuania)

Patterns Of Molecular Sensitization In Adults In Dnipro Region (Ukraine) Kateryna Gashynova (Ukraine)

Features of molecular diagnostics in patients with asthma and allergic rhinitis Galyna Vladymirovna Yeryomenko (Ukraine)

Modern view on management of allergic diseases in Kazakhstan Zhannat Ispayeva (Kazakhstan)

Allergic sensitisation in asthmatic patients followed up at a central hospital in Landa, Angola Margarete Lopes Teixeira Arrais (Angola)

Analysis of distribution characteristics of TIgE and SIgE in patients with respiratory allergic diseases Huimin Huang (China)

A pilot study on the allergen-specific IgE to molecular components on polysensitized mite allergic asthmatic patients in Guangzhou, China Haisheng Hu (China)

Trends in skin prick test according seasons: Results of a Korean multi-center study JIN HEE CHO (South Korea)

Evaluation of a population with and without rhinitis in a tropical city Liliana Guevara (Colombia) IgE- sensitization patterns from three different populations Martina Gunacker (Austria)

Allergy diagnosis and systems medicine > Clinical Allergology > ENT > Asthma

Thematic Poster Sessions (TPS)

TPS 59 Allergen extracts and molecules for veterinary allergology Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 22 in e-Poster Area D (FIL)

Chairs Jozef Janda (Czech Republic) Douglas J. DeBoer (United States)

Variability in Fel D1 in cats is unrelated to cat phenotype but decreases with age Ebenezer Satyaraj (United States)

Allergy approach to a dog population from a veterinary dermatology consultation at the tropical inland city of londrina, Paraná, Brazil Luís Miguel Martins (Portugal)

Development of a new dermatophagoides farinae extract for its specific use in allergic dogs Raquel Moya (Spain)

Dermatological and allergy approach to a dog population from a veterinary consultation at the tropical coastal city of São Paulo, Brazil Luís Miguel Martins (Portugal)

Investigate the impact of cat allergen from different cat breeds on cat sensitized subject using novel progenitor cell derived basophil activation test Jiakai Wu (United Kingdom)

Clinical significance of detecting specific IgE to cat and dog allergens including major allergen components in pet owners Sungryeol Kim (South Korea)

Molecular sensitization profile to animal epithelia in an atopic population Mara Fernandes (Portugal)

Allergens in dog extracts and in a dog population: Implication for diagnosis and treatment Anna Wintersand (Sweden)

Analysis of sensitization profiles in allergy patients focused on animal allergen molecules Martina Vachová (Czech Republic)

Analysis of dust mite allergen components in asthmatic children from Costa Rica and Ecuador: Focus on Der P 23 Behnam Keshavarz (United States)

Evaluation of various methods of clinical and laboratory diagnosis for house dust mite (HDM) sensitisation in patients with HDM-triggered allergic rhinoconjuctivitis Anna Kosowska (Poland)

Clinical relevance of dermatophagoides pteronyssinus sensitization in patients with rhinitis Sofia Martins Farinha (Portugal)

Sensitization to Blomia tropicalis and Ascaris spp. components in recurrent wheezing children living in a tropical city Juan Felipe Lopez (Colombia)

Mold spores in the home as a risk factor of allergic asthma Lawrence DuBuske (United States) Allergen-specific IgE to grass molecular components: Analysis on age, sex and area of provenience Amelia Licari (Italy)

Oropharyngeal symptoms to bell pepper in an adult patient with Bet V 1-related allergy Mariana Vieru (Romania)

Prevalence of sensitization to lipid transfer protein (LTP) and profilin in a sample of 221 patients in Santiago, Chile TERESA PERALTA (Chile)

Sensitization to individual pollen-derived profilins in seasonal allergic rhinitis patients from North Eastern Poland Krzysztof Kowal (Poland)

Importance of anti-CCD sensitization in patients living in Sahel POL ANDRE APOIL (France)

Environmental and occupational allergy > Pediatrics

Thematic Poster Sessions (TPS)

TPS 60 Allergy epidemiology Tuesday, 4 June 2019

12:00-13:30 hrs Room e-Poster station 23 in e-Poster Area D (FIL)

Chairs Adnan Custovic (United Kingdom) Norma Rubini (Brazil)

Secondhand tobacco smoke exposure in early childhood increases the risk of allergic sensitization Kenji Toyokuni (Japan)

The effect of mechanical hot dryer for removing pollens allergens Jae-Won Oh (South Korea)

Prenatal exposure to tobacco is the risk factor for early childhood asthma – polish mother and child cohort study (REPRO_PL) Monika Bobrowska-Korzeniowska (Poland)

Sensitization different between adults and children in Southern China: A survey based on real-world medical data Haisheng Hu (China)

The natural course of inhalant allergen sensitization in the elderly: A 6-year longitudinal follow-up of an elderly general population cohort Byung-Keun Kim (South Korea)

Recently changing pattern of sensitization to aeroallergen in Korean children with allergic diseases: Increasing sensitization to pollen and animal dander Hyo-Bin Kim (South Korea)

Exopolysaccharides isolated from lactobacillus rhamnosus LOCK900 modulate immune response in mouse models of airway allergy Dagmar Srutkova (Czech Republic)

Sensitization pattern and allergy outcome in pregnancy Hanna Danielewicz (Poland)

Beta-lactoglobulin (BLG) accumulates in stable dust associated with zinc: Potential implications for the allergy- and asthma-protective effect Erika Jensen-Jarolim (Austria)

Relationship of the changes in the prevalence of allergic diseases and changes in environmental factors - a cohort study of elementary school Jiho Lee (South Korea)

Influence of dog keeping on indoor dust microbiota Jenni Mäki (Finland)

Factors associated with development of oral allergy syndrome: A retrospective questionnaire survey from Japanese university students Mai Honda (Japan)

The relationship between clinical findings of childhood atopical dermatitis and serum vitamin D levels Abdülkadir Koçak (Turkey)

Patch test is helpful in the majority of oral contact allergy patients due to dental materials ALI CAN (Turkey)

Genotype associations of atopic march at children Volodymyr Dytiatkovskyi (Ukraine)

Epidemiology of allergic diseases among schoolchildren in Kuwait: A cross-sectional study Ali H Ziyab (Kuwait)

Level of knowledge about anaphylaxis among students in the final year of medical school Albertina Varandas Capelo (Brazil)

Early introduction of solids into infants’ diets may reduce the risk of food allergy development Anna Hicke-Roberts (Sweden)

Company Sponsored Symposia (CSS)

CSS 10 Tuesday, 4 June 2019

12:05-13:25 hrs Room Hall 4 (Altice Arena)

Business Meetings (BM)

BM 17 Dermatology Section - Open to all attendees Tuesday, 4 June 2019

12:10-13:20 hrs Room Hall 3 (Altice Arena)

Report on the activities in the Dermatology Board

Reports from the Task Forces

Introductory lecture: What is new in allergology? Carsten Bindslev-Jensen (Denmark)

Business Meetings (BM)

BM 18 Working Group Aerobiology & Pollution - Open to all attendees Tuesday, 4 June 2019 12:10-13:20 hrs Room Hall 5 (Altice Arena)

Introductory lecture: Outdoor molds and respiratory health impact Denis Caillaud (France)

Business Meetings (BM)

BM 19 Section Basic and Clinical Immunology - Open to all attendees Tuesday, 4 June 2019

12:10-13:20 hrs Room Hall 7 (Altice Arena)

Introductory lecture: Mechanisms of oral tolerance development Cecilia Berin (United States)

Report for 2018/19 and planned activities for 2019/20

Open discussion

Business Meetings (BM)

BM 20 Asthma Section - Open to all attendees - Open to all attendees Tuesday, 4 June 2019

12:10-13:20 hrs Room Hall 10 (FIL)

Introductory lecture: Non-type 2 asthma Santiago Quirce (Spain)

Business Meetings (BM)

BM 21 ENT Section - Open to all attendees Tuesday, 4 June 2019

12:10-13:20 hrs Room Hall 11 (FIL)

Introductory Lecture: Genome-scale search for predictive factors in chronic airway diseases Sanna Toppila-Salmi (Finland)

Business Meetings (BM)

BM 22 Working Group Ocular Allergy - Open to all attendees Tuesday, 4 June 2019

12:10-13:20 hrs Room Hall 12 (FIL) Introductory lecture: Exposition environmental chamber: A tool for pathophysiology and treatment of ocular allergy Frédéric de Blay (France)

Allergen immunotherapy > Dermatology > Clinical Allergology > Allied health and primary care

Pro & Con Sessions (P & C)

P & C 5 An adrenalin auto-injector is not needed after starting venom immunotherapy Tuesday, 4 June 2019

12:15-12:45 hrs Room Pro & Con Arena (FIL)

Chair Hanneke Oude Elberink (The Netherlands)

Pro Rodrigo Rodrigues Alves (Portugal)

Con Markus Ollert (Luxembourg)

Pediatrics > Food allergy > Clinical Allergology > Allied health and primary care

Pro & Con Sessions (P & C)

P & C 6 Are the guidelines recommending hydrolysed formula for allergy prevention justified? Tuesday, 4 June 2019

12:45-13:15 hrs Room Pro & Con Arena (FIL)

Chair Alberto Alvarez-Perea (Spain)

Pro Antonella Muraro (Italy)

Con Robert Boyle (United Kingdom)

Company Sponsored Symposia (CSS)

CSS 11 Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 9 (FIL)

Drug allergy > Clinical Allergology > Dermatology Interactive Symposia (ISYM)

ISYM 3 Peri-operative life-threatening allergic reactions Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Josefina Maria Rodrigues Cernadas (Portugal) Maria J Torres (Spain)

Conducting a nationwide audit Susana Marinho (United Kingdom)

The South American experience: Marcelo Vivolo Aun (Brazil)

Lessons learnt and recommendations Shuaib Nasser (United Kingdom)

Basic Allergology > Clinical Allergology > Allergen immunotherapy > Clinical Immunology

Interactive Workshops (IWS)

IWS 8 Immunotherapy in the clinic: Challenges and unmet need Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 6 (Altice Arena)

Chairs Jörg Kleine-Tebbe (Germany) Cemal Cingi (Turkey)

Utility of current diagnostic tools for precision medicine in respiratory allergy Ibon Eguiluz-Gracia (Spain)

Utility of current clinical outcome measures for assessing efficacy of immunotherapy Adam M Chaker (Germany)

Drug allergy

Oral Abstract Sessions (OAS)

OAS 25 Mechanisms and management of drug hypersensitivity Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 10 (FIL)

Chairs Cristobalina Mayorga (Spain) Ozge Soyer (Turkey)

Session roadmap Cristobalina Mayorga (Spain) Synthetic antigenic determinants of clavulanic acid can induce maturation of dendritic cells in immediate allergic reactions to this drug Tahia D Fernandez (Spain)

Characterization of amoxicillin- and clavulanic acid-specific T-cells in patients with amoxicillin-clavulanic acid hypersensitivity reactions Adriana Ariza Veguillas (Spain)

B cell proliferation assay unravels amoxicillin allergy Marcello Albanesi (Italy)

Strongly positive basophil activation with gelatin-containing vaccines for varicella, zoster, measles, mumps and rubella in patients with alpha-gal syndrome Paul Schmidle (Germany)

Smartphone-based patient tailored drug allergy preventive system - pilots study in 4 tertiary hospital Min-Gyu Kang (South Korea)

Relationship between new cases of anaphylaxis and use of beta-blockers: A systematic review and metaanalysis of observational studies Martina Privitera Torres (Spain)

Clinical Immunology > Basic Immunology > Asthma > ENT

Oral Abstract Sessions (OAS)

OAS 26 Cutting edge immunology of airway mucosa Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 11 (FIL)

Chairs Sanna Toppila-Salmi (Finland) Henry McSorley (United Kingdom)

Session roadmap Sanna Toppila-Salmi (Finland)

Distinct microRNA expression patterns after IL-33 challenge in murine lung and bone marrow Emma Winberg (Sweden)

Deciphering human lung mast cell heterogeneity and Wnt signaling Elin Rönnberg Höckerlind (Sweden)

The nasal mucosa of local allergic rhinitis patients harbours IgE+ plasma cells Carmen Rondon (Spain)

Proteomic analysis reveals the potential effects of exosomes on human nasal epithelial cells Min Zhou (China)

Temporal profiling of type 2 airway inflammation markers in nasal mucosal lining fluid following a grass allergen challenge Nehmat Singh (United Kingdom)

Repeated exposure to house dust mite drives persistent activation of inflammatory macrophages Antonie Friedl (Germany)

Environmental and occupational allergy > Pediatrics > Basic Immunology

Oral Abstract Sessions (OAS) OAS 27 Environmental factors influencing allergic responses Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 12 (FIL)

Chairs Jürgen Schwarze (United Kingdom) Barbara Bohle (Austria)

Session roadmap Barbara Bohle (Austria)

Transfer and loss of allergen-specific responses via hematopoietic stem cell transplantation in children: A prospective observational study Thomas Eiwegger (Canada)

Synergistic suppression: Transport of quercetin-iron complexes by beta-lactoglobulin results in immune tolerance due to increased labile iron and activation of the aryl hydrocarbon receptor Franziska Roth-Walter (Austria)

Loading of beta-lactoglobulin confers cross-protection against sensitization to the major birch pollen allergen Bet V 1 in a BALB/c mouse model Franziska Roth-Walter (Austria)

Antibody conjugates Bi-specific for allergens and ICAM1 prevent epithelial allergen penetration and rhinovirus infection Christina Weichwald (Austria)

The effect of triclosan exposure on the development of allergic diseases I-Jen Wang Wang (Taiwan)

Prevalence and predictive factors of pollen food syndrome in a canadian cohort of birch, grass and/or ragweed allergic individuals Sanjeeban Sanju Mishra (Canada)

Food allergy > Pediatrics > Clinical Allergology

Oral Abstract Sessions (OAS)

OAS 28 Achieving tolerance and better quality of life in food allergic patients Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 13 (FIL)

Chairs Jonathan O'B Hourihane (Ireland) Alexandra F. Santos (United Kingdom)

Session roadmap Jonathan O'B Hourihane (Ireland)

Maternal anxiety correlates with infant skin prick test size and inhibits cow’s milk tolerance induction in their infants Jonathan O'B Hourihane (Ireland)

Does introduction of baked milk products increase tolerance to milk proteins in milk-allergic children? Ana Luísa Moura (Portugal)

Spanish children with acute FPIES usually tolerate all other food groups Laura Argiz (Spain)

Validation of food allergy quality of life short forms (FAQLQ-10) for parents, children and teens Audrey DunnGalvin (Ireland)

Improvement in disease-specific quality of life for peanut-allergic subjects receiving AR101 maintenance therapy Jonathan O'B Hourihane (Ireland)

A comparison between the quality of life of children undergoing oral immunotherapy for food allergy and the quality of life depicted by their parents Na'ama Epstein-Rigbi (Israel)

Basic Immunology > Clinical Immunology

Poster Discussion Sessions (PDS)

PDS 23 Microbial influences in immunology Tuesday, 4 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Luis Taborda-Barata (Portugal) Joana Moreno Cosme (Portugal)

Aqueous dispersion of fullerene C60 suppresses the herpes simplex virus 1 infection in vitro and in vivo Ksenia Vadimovna Kozhikhova (Russia)

Cytokine profile of patients with allergopathy in active and latent phases of chronic epstein-barr viral infection Svitlana Zubchenko (Ukraine)

Persistence of rhinovirus in human nasal epithelial cells with waning innate immune activation Hsiao Hui Ong (Singapore)

Impaired immune response of influenza-specific T cells in atopic dermatitis patients Stephan Traidl (Germany)

S. Aureus superantigens in asthma and allergic rinitis: Bacterial immunotherapy as an alternative treatment Galyna Nazarenko (Ukraine)

Frequency of helicobacter pylori and response to its treatment in the clinical evolution of patients with chronic urticaria Larissa de Queiroz Mamede (Brazil)

The link between allergies and microbiota of the airways in patients with bronchiectasis Kateryna Gashynova (Ukraine)

Lipopolysaccharide content in germ-free mouse diet affects the development of T regulatory cells and allergic senzitization Hana Kozakova (Czech Republic)

Immune cell gene expression is modulated by structural components of meningococcus and pneumococcus Lawrence DuBuske (United States)

The Effects Of Antibiotics On The Development Of Asthma And Other Allergic Diseases In Children And Adolescents Soo Whan Kim (South Korea)

Pediatrics > Clinical Allergology > Dermatology

Poster Discussion Sessions (PDS) PDS 24 Drug allergy and atopic dermatitis in children Tuesday, 4 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Eva Gomes (Portugal) Antonino Romano (Italy)

Hypersensitivity reactions to non-steroidal anti-inflammatory drugs in children and adolescents ozge yilmaz topal (Turkey)

Does penicillin allergy exist among children? Tatiana Voltsinger (Israel)

Temporal trends in hay fever and eczema prevalence in a developing country Emilija Georgi Vlashki (Macedonia, Former Yugoslav Republic of)

Four phenotypes of atopic dermatitis in Japanese children: A birth cohort study Kiwako Yamamoto-Hanada (Japan)

Gut microbiome in infancy; the role of butyrate in atopic dermatitis development Carina Madelen Saunders (Norway)

Metagenomic analyses for skin microbiota and metabolic pathways in children with eczema Ting Fan Leung (Hong Kong SAR)

Staphylococcus spp. Toxins production in children with atopic dermatitis Asya Kudryavtseva (Russia)

Transepidermal water loss values in portuguese teenagers: A reference dataset Daniela Brandão Abreu (Portugal)

Sleep quality in children with atopic dermatitis and response to treatment Arturo Borzutzky (Chile)

“You try to take as little as possible”- a qualitative study of young adults with eczema recruited from the population-based birth cohort (BAMSE) Susanne Lundin (Sweden)

Quality of life of children with atopic dermatitis ozge yilmaz topal (Turkey)

Asthma

Poster Discussion Sessions (PDS)

PDS 25 Asthma: Epidemiology to real-life evidence Tuesday, 4 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Giorgio Walter Canonica (Italy) Désirée Erlinda Sophia Larenas-Linnemann (Mexico)

Sensitization to animal allergen components in relation to asthma among young adults in Northern Sweden Eva Rönmark (Sweden)

Evidence that asthma is still increasing in young adults Styliana Vasileiadou (Sweden)

The burden of pediatric asthma. First results of the gan study in mexico Nayely Reyes Noriega (Mexico)

Does asthma lose its importance in respiratory system deaths? SEDAT ALTIN (Turkey)

Identification of severe asthma patients eligible for anti-IL-5 or anti-IgE treatment: Findings from a korean asthma cohort, COREA Ji-Hyang Lee (South Korea)

Factors associated with severity in children with asthma Eun Sang Rhee (South Korea)

Clusters of asthma control: Data from the Portuguese inspirers studies Cristina Jácome (Portugal)

Identification of asthma phenotypes in the US general population: A latent class analysis approach Rita Amaral (Portugal)

Comparison of data fields captured by regional severe asthma registries participating in the international severe asthma registry (ISAR) Neva Eleangovan (United Kingdom)

Bronchiectasis as an aggravating factor for severe asthma: Data from the “Severe Asthma Network Italy” (SANI) registry Enrico Heffler (Italy)

Respiratory infection in elite swimmers – a prospective surveillance study Diana Margarida Silva (Portugal)

Association of asthma and sleep insufficiency among south korean adolescents: Analysis of web-based self-reported data from the korean youth risk behavior web-based survey Woon Kyung Shin (South Korea)

A mobile telephone-based interactive self-care system may improve asthma quality of life I-Jen Wang Wang (Taiwan)

Characteristic of lithuanian MASK allergy diary users Violeta Kvedariene (Lithuania)

Clinical improvement in non-allergic patients treated with omalizumab in real-life: FENOMA study Stefan Cimbollek (Spain)

Food allergy > Pediatrics

Poster Discussion Sessions (PDS)

PDS 26 Management of food allergy Tuesday, 4 June 2019

13:30-15:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Barbara Ballmer-Weber (Switzerland) Zeynep Ulker Tamay (Turkey)

Baseline demographics of >1100 peanut-allergic subjects aged 4-17 years randomised in three double-blind placebo-controlled phase 3 AR101 trials: PALISADE, RAMSES And ARTEMIS Wayne G Shreffler (United States)

Real-world experience and management of peanut allergy: A quantitative study of adolescents with peanut allergy in the united states Christine Birchwood (United States)

Hypoallergenicity of a whey-based, extensively hydrolysed infant formula containing two human milk oligosaccharides Anna Halina Nowak-Wegrzyn (United States)

Negative phychosocial effect of dietary elimination on breastfeeding mothers having infants with and without food allergy Ozlem Yilmaz (Turkey)

Allergic reaction after accidental peanut exposure in a randomized, placebo-controlled trial on peanut oral immunotherapy Valérie Trendelenburg (Germany)

Mitochondrial vs allergen-encoding genes for milk detection in processed foods Caterina Villa (Portugal)

Are schools banning nuts? Results from a population-based survey of Australian schools Vicki Mcwilliam (Australia)

Reintroduction failure after negative food challenges is common and main reason is symptoms Astrid Versluis (The Netherlands)

The role of usability in digitized nutritional counselling settings Janina Sauer (Germany)

What a restaurant staff knows about food allergy? - Impact of a face-to-face training course Inês Pádua (Portugal)

Food allergy knowledge and attitudes of restaurant managers and staff in beirut region: A pilot study Dominique Dano (Lebanon)

Sister Society Symposia (SSS)

SSS 12 EAACI – APAAACI Joint Symposium: The human microbiome and role of probiotics for allergic disorders in Asia Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 7 (Altice Arena)

Chairs Takao Fujisawa (Japan) Yoon-Seok Chang (South Korea)

Microbiome and allergic diseases in Asia Ruby Pawankar (Japan)

Role of probiotics in children with food allergy Lynette Shek (Singapore)

From prebiotics, probiotics, to post-biotics in the prevention of atopic dermatitis Jiu-Yao Wang (Taiwan)

Clinical Allergology > Allergen immunotherapy > Pediatrics > Allergy diagnosis and systems medicine

Symposia (SYM)

SYM 31 Aeroallergen challenge tests in daily practice and in clinical trials Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 1 (Altice Arena)

Chairs Peter Socrates Creticos (United States) Ralph Mösges (Germany)

Allergen challenge as diagnostic tools in a clinical setting Paloma Campo (Spain)

Allergen challenge as outcome measures in immunotherapy trials Frédéric de Blay (France)

The regulatory view on allergen challenge and legal implications for the physician Vera Mahler (Germany)

Allergen immunotherapy > Clinical Allergology > Food allergy

Symposia (SYM)

SYM 32 Improving safety of food allergy immunotherapy Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 2 (Altice Arena)

Chairs Montserrat Alvaro Lozano (Spain) Kari Christine Nadeau (United States)

Oral immunotherapy with baked foods: Better results and less adverse events? Carmen Riggioni (Spain)

Eosinophilic esophagitis as an adverse event during and after oral immunotherapy Antonella Cianferoni (United States)

Efficacy and safety of vital wheat gluten oral immunotherapy Kirsten Beyer (Germany)

Dermatology > Clinical Allergology > Clinical Immunology

Symposia (SYM)

SYM 33 Skin disease management – from prevention to treatment Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 3 (Altice Arena)

Chairs Charlotte G. Mortz (Denmark) Clive Grattan (United Kingdom)

Can we prevent atopic dermatitis by skin barrier modulation? Pasquale Comberiati (Italy)

Novel allergens in allergic contact dermatitis Wolfgang Uter (Germany)

Treatment of chronic idiopathic urticaria – when anti-IgE fails Ana M Giménez-Arnau (Spain)

Allied health and primary care > Clinical Allergology Symposia (SYM)

SYM 34 Can a multi-disciplinary team approach improve care of the allergic patient? Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 5 (Altice Arena)

Chairs Berber Vlieg-Boerstra (The Netherlands) Carmen Vidal (Spain)

Dietitian- liberating management Emilia Vassilopoulou (Cyprus)

Clinical psychologist – making a difference in clinical care Rebecca Knibb (United Kingdom)

Nurse – guidance for keeping safe Inger Kull (Sweden)

Asthma > Pediatrics

Year in Review Sessions (YIR)

YIR 6 Year in Review: Asthma Tuesday, 4 June 2019

13:30-15:00 hrs Room Hall 14 (FIL)

Chairs Ioana Octavia Agache (Romania) Victoria del Pozo (Spain)

Long and winding road: From infant wheeze to adult asthma Louise Fleming (United Kingdom)

Next generation beta adrenoreceptor agonists for the treatment of asthma Mario Cazzola (Italy)

Microbiome and its effect on the immune responses in asthma Yvonne Jean Huang (United States)

Pediatrics > Food allergy > Ocular Allergy > Precision Medicine

Thematic Symposia (TSYM)

TSYM 6 Leading ladies in science symposia - Novel approaches in management of allergic diseases Tuesday, 4 June 2019

13:45-15:00 hrs Room Hall 4 (Altice Arena)

Chairs Antonella Muraro (Italy) Susanne Halken (Denmark)

United airways updated Glenis Kathleen Scadding (United Kingdom)

Exposomics in personalized prevention: How big data can help in clinical practice ? Isabella Annesi-Maesano (France)

Big data and biocomputing in personalised medicine: How useful is in clinical practice? Kathleen Barnes (United States)

Highlights Sessions (HS)

HS 3 Highlights on Food Allergy: The burden of peanut allergy: Psychosocial and economic impact Tuesday, 4 June 2019

15:05-15:20 hrs Room Pro & Con Arena (FIL)

Chair Margitta Worm (Germany)

Interview on the topic "The burden of peanut allergy: Psychosocial and economic impact" Ioana Maris (Ireland)

Asthma > Clinical Allergology > Food allergy > Pediatrics

Ethics Session

Use and prescription of adrenaline auto-injectors: Ethical aspects Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 5 (Altice Arena)

Chairs Glenis Kathleen Scadding (United Kingdom) Sergio Bonini (Italy)

Current and future practical difficulties for those patients prescribed an adrenalin pen Adam Fox (United Kingdom)

Psychological impact of prescribing AAIs Mikaela Odemyr (Belgium)

Generic AAI prescriptions in schools: Pro/Con Antonella Muraro (Italy)

Ethical discussion Glenis Kathleen Scadding (United Kingdom)

Company Sponsored Symposia (CSS)

CSS 12 Tuesday, 4 June 2019 15:30-17:00 hrs Room Hall 8 (FIL Meeting Centre)

Clinical Allergology > Allergy diagnosis and systems medicine > Food allergy > Precision Medicine

Interactive Workshops (IWS)

IWS 9 Molecular allergology Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 6 (Altice Arena)

Chairs Carmen Vidal (Spain) Ronald van Ree (The Netherlands)

Allergy to fish: New diagnostic developments Annette Kuehn (Luxembourg)

Pollen food syndrome: What are the relevant molecules? Isabel Janet Skypala (United Kingdom)

Dermatology > Biologicals > Clinical Allergology

Late Breaking Oral Abstract Sessions (LB OAS)

LB OAS 02 New insights in skin hypersensitivity Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 12 (FIL)

Chairs Sofia Campina (Portugal) Jose Luis Garcia-Abujeta (Spain)

Session roadmap Sofia Campina (Portugal)

Efficacy and safety data of AK002, an anti-siglec-8 monoclonal antibody, in patients with multiple forms of uncontrolled chronic urticaria (CU): Results from an open-label phase 2a study Marcus Maurer (Germany)

Electrical impedance spectroscopy as a safe and efficient tool for the characterization of epidermal barrier in atopic dermatitis Arturo Rinaldi (Italy)

Skin barrier changes upon exposure to p-phenylenediamine in hair dye allergic individuals and occupationally exposed non-responding individuals Sanne Skovvang Steengaard (Denmark)

Single nucleotide polymorphisms of IgE regulatory pathways in atopic dermatitis Jeng Sum Charmaine Kung (Hong Kong SAR)

Effects of calcium and magnesium ions on AQP3 expression in keratinocytes Ryo Muko

Information and Communication Technology in Chronic Urticaria: UCARE PROJECT Ivan Cherrez Ojeda (Ecuador) Basic Immunology > Clinical Immunology > Clinical Allergology

Late Breaking Oral Abstract Sessions (LB OAS)

LB OAS 03 Advances in cellular immunology Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 14 (FIL)

Chairs Carsten Schmidt-Weber (Germany) Eva Untersmayr (Austria)

Session roadmap Carsten Schmidt-Weber (Germany)

PVX108 – a peptide-immunotherapy for peanut allergy shows exceptional safety in peanut-allergic adults Sara Prickett (Australia)

The TLR2/MyD88, an inhibitory pathway of the allergic response induced by Aspergillus fumigatus spores through the IL-10 cytokine Pauline Percier-Lehebel (Belgium)

Allergooncology: Delayed glioblastoma progression in a mouse model of allergic airway inflammation Aurélie Poli (Luxembourg)

Allergooncology: The basophil activation test to monitor hypersensitivity to an anti-cancer IgE undergoing first-in-class, first-in-man clinical trial Chara Stavraka (United Kingdom)

T regulatory and T effector cells display distinct metabolic profiles in allergic patients Juan Rodriguez-Coira (Spain)

Food allergy > Pediatrics > Clinical Immunology

Oral Abstract Sessions (OAS)

OAS 29 Food allergy and eosinophilic esophagitis Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 9 (FIL)

Chairs Ingrid Terreehorst (The Netherlands) Carina Venter (United States)

Session roadmap Ingrid Terreehorst (The Netherlands)

Basophil and mast cell responses to food allergens in sensitised but tolerant patients are not mediated via the FcgRIIa and FcgRIIb receptors Richard Thomas McKendry (United Kingdom)

Subclinical esophageal eosinophilia is present in some peanut allergic patients R. Sharon Chinthrajah (United States)

Efficacy of RPC4046, an anti-interleukin-13 monoclonal antibody, in patients with active eosinophilic esophagitis: analysis of the steroid-refractory subgroup from the heroes study Ekaterina Safroneeva (Switzerland)

Molecular restoration in eosinophilic esophagitis patients after treatment with proton-pump inhibitors José Antonio Cañas (Spain)

Markers of Esophageal Epithelial-Mesenchymal Transition Are Significantly Reduced in Active EoE Following 16 Weeks of Treatment With RPC4046, an Anti-Interleukin-13 Monoclonal Antibody Margaret Collins (United States)

Drug allergy > Clinical Allergology

Oral Abstract Sessions (OAS)

OAS 30 Epidemiology and clinical aspects of drug hypersensitivity Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 10 (FIL)

Chairs Joana Sa Caiado (Portugal) Ozge Soyer (Turkey)

Session roadmap Joana Sa Caiado (Portugal)

Evaluation of the drug hypersensitivity reactions in the geriatric population pelin karadag (Turkey)

Anaphylaxis to clavulanic acid: Frequency and clinical characterization António Miguel Silveira

Selective hypersensitivity reactions to NSAIDs and differences between pharmacological groups Natalia Pérez-Sánchez (Spain)

Are skin tests for general anesthetics necessary in atopics and patients with other drug allergies? sengül beyaz (Turkey)

Perioperative anaphylaxis in children: Etiology, time sequence and patterns of reactivity Ekaterina Khaleva (United Kingdom)

Hypersensitivity Reactions To Anesthetics In Children Vladimir Tmusic (Serbia)

Asthma > Precision Medicine > Basic Allergology

Oral Abstract Sessions (OAS)

OAS 31 Biomarkers in precision medicine in asthma Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 11 (FIL)

Chairs André Moreira (Portugal) Stefano R Del Giacco (Italy)

Session roadmap André Moreira (Portugal) Serum MiRNA expression is associated with asthma control and airway inflammation in non-elderly asthmatics Aleksandra Wardzynska (Poland)

Novel metabolomic biomarkers associated with HDM-allergic asthma severity Maria M Escribese (Spain)

Relationship between lung function abnormalities, blood and bronchoalveolar lavage biomarkers and airway structural changes in asthma Pawel Kozlik (Poland)

Human volatilome analysis using ENose to assess uncontrolled asthma in a clinical setting Mariana Valente Farraia (Portugal)

Role of osteopontin in late-onset asthma Tu Hoang Kim Trinh (Viet Nam)

YKL-40 As biomarker in severe asthma Margarida Cortez E Castro (Portugal)

Food allergy > Basic Allergology

Oral Abstract Sessions (OAS)

OAS 32 Characterization and mechanisms of food allergens Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 13 (FIL)

Chairs Karin Hoffmann-Sommergruber (Austria) Carsten Bindslev-Jensen (Denmark)

Session roadmap Karin Hoffmann-Sommergruber (Austria)

Identification of gibberellin-regulated protein as a new allergen in cherry allergy Naoko Inomata (Japan)

IgE to epitopes of Ara H 2 enhance the diagnostic accuracy of Ara H 2-Specific IgE Oliver Hemmings (United Kingdom)

Allergenicity and cross-reactivity of different variants of the peanut allergen Ara H 2 Anniek van de Velde (Denmark)

Late reaction in Gal-Alpha-Gal allergy is reflected in serum levels after ingestion of pork kidney Esben Eller (Denmark)

IgE-reactive proteins defined by 88 fish-allergic children, predicting the allergenicity of 66 asia-pacific fish species Thimo Ruethers (Australia)

Egg yolk acts as adjuvant activating innate immune responses to egg white allergens in BALB/C MICE Daniel Lozano-Ojalvo (Spain)

Food allergy > Clinical Immunology

Poster Discussion Sessions (PDS)

PDS 27 Gastrointestinal immunology and eosinophilic esophagitis Tuesday, 4 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area A (FIL)

Chairs Antonella Cianferoni (United States) Gunnur Deniz (Turkey)

Eosinophilic esophagitis: Association with atopic diseases and IgE mediated food allergy Pablo Torres (Ecuador)

Deep remission in eosinophilic esophagitis: Looking beyond eosinophils Larissa de Queiroz Mamede (Brazil)

Eosinophilic esophagitis and gastritis patient biopsies have high levels of activated eosinophils and mast cells that are inhibited by AK002 Bradford A. Youngblood (United States)

Eosinophilic esophagitis – comparing two types of diet Mariana Lobato (Portugal)

Long-term efficacy and safety of RPC4046, an anti-interleukin-13 monoclonal antibody, in patients with eosinophilic esophagitis: Results from the open-label extension of the heroes study Ekaterina Safroneeva (Switzerland)

Infant stool IgA-bound microbiome in older order mennonites (OOM) with a low prevalence of pediatric food allergy (FA) Kirsi M. Jarvinen-Seppo (United States)

Cord blood eosinophils were elevated in non-IgE-mediated gastrointestinal food allergy whose onset was in the early neonatal period Ichiro Nomura (Japan)

Metabolic profile of a murine model of allergic enteritis Elisa Violeta Zubeldia-Varela (Spain)

Food protein induced enterocolitis syndrome: Lessons from a pediatric US population Katherine Anagnostou (United Kingdom)

Progenitor cell-derived basophils: A novel passive degranulation assay in peanut allergy diagnosis Jiakai Wu (United Kingdom)

IgE binding-based and crosslinking-based tests for the diagnosis of shrimp allergy Yee Yan Christine Wai (Hong Kong SAR)

Late and “pseudo-biphasic” anaphylaxis reactions during food challenges to peanut Goncalo Abrantes (United Kingdom)

Imperative sleepiness: An underestimated symptom of allergic reactions Birgit Kalb (Germany)

Environmental and occupational allergy

Poster Discussion Sessions (PDS)

PDS 28 Workplace exposure and occupational allergy Tuesday, 4 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area B (FIL)

Chairs Monika Raulf (Germany) Jolanta Walusiak-Skorupa (Poland) Allergic sensitization in veterinary medicine students Ana Margarida Mesquita (Portugal)

Prevalence of allergy symptoms and the hypersensitivity to occupational allergens among apprentices of culinary school in the last year of education Marta Wiszniewska (Poland)

Diagnostic values of skin prick test and allergen-specific IgE in evaluating laboratory animal allergy among Korean laboratory animal researchers Sang Min Lee (South Korea)

Which came first: The chicken, the quail or the egg? Cristiana Cancela Ferreira (Portugal)

Occupational contact urticaria caused by epoxy resins: A case report Diana Betancor (Spain)

Severe asthma by inhalation of squid steamer María Karina Magdalena Bethencourt (Spain)

Flour sensitization in a factory of wooden doors - what is the relationship? Joana Queirós Gomes (Portugal)

Work-related allergic asthma: Clinical work-up of a 45-year old male working in animal feed producing industry Johannes Martin Schmid (Denmark)

A case of hypersensitivity pneumonitis Emine Vezir (Turkey)

Isocyanate-induced occupational asthma and specific inhalation tests in Czech Republic Pavlina Klusackova (Czech Republic)

Rhinoconjunctivitis and work-exacerbated asthma caused by rice allergy Melvin Vásquez Suero (Dominican Republic)

Occupational asthma in the Czech Republic between years 2011-2017 Bronislava Viest (Czech Republic)

Occupational rhinoconjunctivitis induced by unusual allergens of María Karina Magdalena Bethencourt (Spain)

Recurrent angioedema and suspect occupational asthma in a patient with thyrotoxicosis Clinical case report Petar Kirilov Dimov (Bulgaria)

Allergen immunotherapy > Precision Medicine > Basic Allergology > Clinical Allergology

Poster Discussion Sessions (PDS)

PDS 29 Novel approaches to allergen immunotherapy Tuesday, 4 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area C (FIL)

Chairs Désirée Erlinda Sophia Larenas-Linnemann (Mexico) Joana Moreno Cosme (Portugal)

A faster method of immunotherapy with allergoids - safety and tolerance in children Joanna Lange (Poland)

Bet V 1 COP-Virosomes Elicit Strong Th1 Response In Mice Alexander Kettner (Switzerland)

Bacterial cell wall fragment glucosaminyl muramyl dipeptide in treatment of allergic disease Svetlana Guryanova (Russia)

Allergenicity of grass depigmented-polymerized extracts by basophil activation test M. Angeles Lopez-Matas (Spain)

Qualitative and quantitative analysis of epithelial allergens by mass spectrometry Steffen Augustin (Germany)

Characterization of a new allergoid from ambrosia artemisiifolia Marcos Peñalver Mellado (Spain)

Effects of different adjuvants on house dust mite allergy and allergens-specific immunotherapy in a murine model of allergic asthma Alexander Heldner (Germany)

Reduced proteolytic activity of an alternaria alternata allergoid and stability of its mixture with an olea europaea allergoid Marcos Peñalver Mellado (Spain)

Particle characterization of house dust mite products for subcutaneous immunotherapy Anne Cossé (Germany)

Fel d1 blocking antibodies against the major cat allergen Fel d1 Ebenezer Satyaraj (United States)

Cyclic immunologic changes of maintenance phase subcutaneous immunotherapy in house dust mite allergy Nada Chaoul (Lebanon)

Making the allergen look like a virus: An immunogenic, protective and non-reactogenic vaccine candidate against peanut allergy Matthew D. Heath (United Kingdom)

The diverse T cell responses in ragweed allergic patients are highly cross-reactive and independent of geographical region Peter Adler Würtzen (Denmark)

ENT > Basic Immunology > Biologicals > Basic Allergology

Poster Discussion Sessions (PDS)

PDS 30 Rhinosinusitis and nasal polyps from bench to bedside Tuesday, 4 June 2019

15:30-17:00 hrs Room PDS Dome in e-Poster Area D (FIL)

Chairs Sanna Toppila-Salmi (Finland) Jose Ferreira (Portugal)

CRTH2 MRNA levels in peripheral blood of adult patients with nasal polyposis Ignacio J. Dávila (Spain)

The change of clinical and histological characteristics of chronic rhinosinusitis with nasal polyps in 18 years: Was there an eosinophilic shift in South China? xin luo (China)

Involvement of phosphoinositide 3-kinase-delta in the development of eosinophilic nasal polyps in chronic rhinosinusitis Yong Chul Lee (South Korea)

The role of purinergic receptor P2X7 in chronic rhinitis with nasal polyp Ilgyu Kong (South Korea)

Mitochondrial dysfunction and structural alterations are associated with nasal polyposis and staphylococcus aureus enterotoxin B induced oxidative stress Younghoon Yoon (South Korea)

An integrated analysis of radial spoke head and outer dynein arm protein defects and ciliogenesis abnormality in nasal polyps Wei Jie Guan (China)

Radiation treatment decreases markers of ciliogenesis, cilia structure, goblet cell, and basal cell MRNA expression in nasal epithelium of nasopharyngeal carcinoma Sui-zi ZHOU (China)

Therapeutic effects of tofacitinib for CRSwNP using a murine model Yeonhee Joo (South Korea)

The effect of budesonide repulses nasal drop for the short-course treatment for chronic rhinosinusitis with nasal polyps: A randomized controlled clinical trial Zhaofeng Xu (China)

Baseline characteristics of phase 3 randomized controlled trials of omalizumab in chronic rhinosinusitis with nasal polyps Claus Bachert (Belgium)

Dupilumab reduces need for systemic corticosteroid use, sinonasal surgery in patients with severe chronic rhinosinusitis with nasal polyps: Pooled results from the SINUS-24, SINUS-52 phase 3 studies Claus Bachert (Belgium)

Assessing self-reported nasal hyperreactivity in chronic rhinosinusitis. A two-institutional questionnaire survey Brecht Steelant (Belgium)

Sister Society Symposia (SSS)

SSS 13 EAACI – SLAAI Joint Symposium: Emerging concepts in pediatric allergy Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 7 (Altice Arena)

Chairs João Negreiros Tebyriçá (Brazil) Edgardo Jares (Argentina)

New evidences of epigenetic and environmental influence in the development of allergy Hector Badellino (Argentina)

Small airways disease in children Nelson Rosario (Brazil)

Pediatric drug induced anaphylaxis in Latin América Luis Felipe Chiaverini Ensina (Brazil)

Asthma > Allergen immunotherapy > Environmental and occupational allergy

Symposia (SYM)

SYM 35 National Allergy Society Forum: Scientific highlights from the NAS Committee Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 1 (Altice Arena)

Chairs Beatrice Biló (Italy) Ioana Octavia Agache (Romania)

SCIT in real life Asli Gelincik (Turkey)

Sensitization to perennial inhalant allergen components in allergy patients in the Central European region Petr Panzner (Czech Republic)

Biological function of eosinophil extracellular traps in patients with severe eosinophilic asthma Hae-Sim Park (South Korea)

Food allergy > Biologicals > Allergen immunotherapy > Precision Medicine

Symposia (SYM)

SYM 36 Therapeutic strategies in immune modulation of allergic diseases Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 2 (Altice Arena)

Chairs Liam O'Mahony (Ireland) Jürgen Schwarze (United Kingdom)

Combined alllergen immunotherapy and biologicals in food allergy Philippe Bégin (Canada)

Targeting microbiota for oral food immunotherapy Mimi L. K. Tang (Australia)

Targeting MicroRNAs in allergic diseases Madeleine Radinger (Sweden)

Dermatology > Clinical Allergology > Allergy diagnosis and systems medicine > Clinical Immunology

Symposia (SYM)

SYM 37 How to classify cutaneous manifestations of drug hypersensitivity? Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 3 (Altice Arena)

Chairs Marcelo Vivolo Aun (Brazil) Peter Schmid-Grendelmeier (Switzerland)

Algorithm for classification of cutaneous manifestations of drug hypersensitivity Knut Brockow (Germany)

Clinical presentations of cutaneous drug hypersensitivity Charlotte G. Mortz (Denmark)

Diagnostics problems, pitfalls and clues in cutaneous drug hypersensitivity Maria J Torres (Spain)

Asthma > Pediatrics > Clinical Allergology Symposia (SYM)

SYM 38 Understanding and changing the lifetime trajectory of asthma Tuesday, 4 June 2019

15:30-17:00 hrs Room Hall 4 (Altice Arena)

Chairs Susanne Halken (Denmark) Gustavo Wandalsen (Brazil)

Trajectories of asthma from childhood into adulthood Erik Melén (Sweden)

Metagenomic regulation of asthma activity Nikolaos Papadopoulos (Greece)

Targeting the microbiome as possible tool to prevent asthma Susanne Krauss-Etschmann (Germany)

Business Meetings (BM)

BM 23 Working Group Allergy, Asthma and Sports - Open to all attendees Tuesday, 4 June 2019

17:30-18:40 hrs Room Hall 5 (Altice Arena)

Brief presentation by the Chair and Secretary

Introductory lecture: Exercise in allergic disease: Drawbacks and benefits Diana Margarida Silva (Portugal)

Presentation of the Working Group activities and further plans for the future

Discussion

Business Meetings (BM)

BM 24 Patient Organising Committee - Open to all attendees Tuesday, 4 June 2019

17:30-19:00 hrs Room Hall 7 (Altice Arena)

Introductory lecture: Improving accuracy and safety of food allergy diagnosis Alexandra F. Santos (United Kingdom)

Sister Society Symposia (SSS) SSS 14 EAACI – IRINE Joint Symposium: 30 Year Anniversary of the Immunology Research of New England Tuesday, 4 June 2019

17:30-19:00 hrs Room Hall 1 (Altice Arena)

Chairs R Khanferyan (Russia) Lawrence DuBuske (United States)

Obesity and cytokines in asthma Igor Kaidashev (Ukraine)

New applications of dendritic cell immunotherapy Andrei Hancharou (Belarus)

Lawrence DuBuske (United States)

Genetic polymorphisms in asthma Yuriy Bisyuk (Ukraine)

Climate change and pollen season change Victoria Rodinkova (Ukraine)

Allergen immunotherapy

Plenary Symposia (PL)

PL 7 In Memoriam of Anthony J Frew: Allergen Immunotherapy (AIT): Conceptualising the future and beyond Wednesday, 5 June 2019

08:30-10:00 hrs Room Hall 1 (Altice Arena)

Chairs Mohamed Shamji (United Kingdom) Helen Smith (United Kingdom)

Anthony J Frew Helen Smith (United Kingdom)

Anthony Barry Kay (United Kingdom)

Aeroallergen AIT: Evidence meets innovations Stephen R Durham (United Kingdom)

Clinical trials: Improving trial designs in the age of evidence-based medicine Oliver Pfaar (Germany)

Evidence gaps and research priorities in allergen immunotherapy Marek Jutel (Poland) Dermatology > Pediatrics > Clinical Allergology > Clinical Immunology

Interactive Workshops (IWS)

IWS 10 How to differentiate between cutaneous manifestations- the diagnosis is not always easy Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 6 (Altice Arena)

Chairs Susan Chan (United Kingdom) Clive Grattan (United Kingdom)

Atopic dermatitis or allergic contact dermatitis? Peter Schmid-Grendelmeier (Switzerland)

Chronic urticaria or autoinflammatory syndrome? Antti Ilmari Lauerma (Finland)

Asthma > Pediatrics > Environmental and occupational allergy > Clinical Allergology

Late Breaking Oral Abstract Sessions (LB OAS)

LB OAS 04 Novel therapies in asthma Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 8 (FIL Meeting Centre)

Chairs Victoria del Pozo (Spain) Zuzana Diamant (The Netherlands)

Session roadmap Zuzana Diamant (The Netherlands)

DUSP1 plays a pivotal role in MAPK signaling in childhood asthma development and environment-mediated protection Johanna Krusche (Germany)

Effectiveness of high-altitude climate therapy in adults with severe refractory asthma Selma de Nijs

Single-dose Phase 2a trial of etokimab (anti-IL-33) in severe eosinophilic asthma Marco Londei (Italy)

Goat’s milk feeding enhances innate and adaptive immunities and alleviates allergen-induced airway inflammation in offspring mice Hui-Fang Kao (Taiwan)

The link between infections and sIgE and sIgG4-autoabs to lung elastin, collagen type III and myosin in bronchial asthma Anna Konishcheva (Russia)

Pathway analysis - genetic and immunological influences of gene polymorphisms in 17q21 locus on childhood wheeze Kristina Laubhahn (Germany) Clinical Immunology > Basic Immunology > Clinical Allergology > Basic Allergology

Oral Abstract Sessions (OAS)

OAS 33 Links between microbes and allergy Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 5 (Altice Arena)

Chairs Wojciech Feleszko (Poland) Luís Delgado (Portugal)

Session roadmap Wojciech Feleszko (Poland)

Surfactant protein A (SP-A) reduces human rhinoviruse C (RV-C)-induced inflammation responses and viral replication in pediatric nasal epithelial cells Sasipa - Tanyaratsrisakul (United States)

Antiviral immune response deficiency of nasal epithelial cells from asthmatic patients after RV1B infection Styliani Taka (Greece)

RNA sequencing revealed transcriptomic changes of the human nasal epithelium following human influenza infection Kai Sen Tan (Singapore)

MV130, a polybacterial mucosal preparation, protects mice against experimental viral infections inducing trained immunity Laura Conejero Hall (Spain)

Microbiome correlates of success of treatment of atopic dermatitis with the JAK/SYK inhibitor ASN002 Avidan Uriel Neumann (Germany)

Modulation of the myeloid arachidonic acid metabolism imparts helminth-driven control of type 2 inflammation Antonie Friedl (Germany)

Clinical Immunology > Biologicals > Asthma > Food allergy

Oral Abstract Sessions (OAS)

OAS 34 Biologicals bench to bedside Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 7 (Altice Arena)

Chairs Oscar Palomares (Spain) Thomas Eiwegger (Canada)

Session roadmap Oscar Palomares (Spain)

Omalizumab in spontaneuos food tolerance in adult patients David El-Qutob (Spain)

The immunological signatures of success or failure following peanut oral immunotherapy combined with individualized omalizumab treatment in peanut allergic adolescents Marieke van der Heiden (Sweden) Targeting birch allergy with monoclonal IgG antibodies that bind allergen and prevent IgE effector cell activation Jamie M. Orengo (United States)

Inhibition of mast cells with a Siglec-8 antibody reduces tissue damage in models of skin and lung fibrosis and COPD Bradford A. Youngblood (United States)

Molecular, structural and mechanistic insight into ligelizumab mediated suppression of IgE dependent allergic responses Alexander Eggel (Switzerland)

Real-life study of patients treated with omalizumab for chronic spontaneous urticaria in france: 6 months data of the LUCIOL study Laurence Bouillet (France)

Asthma > Basic Immunology > Clinical Allergology > Precision Medicine

Symposia (SYM)

SYM 39 Targeting the IL-5 pathway: Asthma and beyond Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 1 (Altice Arena)

Chairs Martina Vasakova (Czech Republic) Pedro Carreiro-Martins (Portugal)

Why IL5? The role in allergic diseases Anthony Barry Kay (United Kingdom)

Anti-IL5 in lower airways Martina Vasakova (Czech Republic)

Anti-IL5 in upper airways Claus Bachert (Belgium)

Food allergy > Dermatology > Pediatrics > Clinical Allergology

Symposia (SYM)

SYM 40 Expanding the role of prevention in allergy Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 3 (Altice Arena)

Chairs Michael Perkin (United Kingdom) João Almeida Fonseca (Portugal)

Skin barrier interventions for prevention of atopic dermatitis Maeve M. Kelleher (United Kingdom)

Targeting the microbiome to prevent food allergy Roberto Berni Canani (Italy)

Preventing respiratory allergy with specific immunotherapy Susanne Halken (Denmark)

Allergen immunotherapy > Clinical Allergology > Basic Immunology

Symposia (SYM)

SYM 41 Current and future perspective on adjuvants for allergen immunotherapy Wednesday, 5 June 2019

10:30-12:00 hrs Room Hall 4 (Altice Arena)

Chairs Ludger Klimek (Germany) Mübeccel Akdis (Switzerland)

Standard adjuvants: Advantages and limitations Erika Jensen-Jarolim (Austria)

Novel adjuvants in clinical development for AIT Thomas Kündig (Switzerland)

What should the “ideal” adjuvant immunologically achieve? Carsten Schmidt-Weber (Germany)

Closing Ceremony

Closing Ceremony Wednesday, 5 June 2019

12:15-13:15 hrs Room Hall 2 (Altice Arena)

Closing Reception

Closing Reception Wednesday, 5 June 2019

13:15-14:15 hrs Room Main Foyer (Altice Arena)