Drugs to Avoid in G6pd Deficiency

Home , Acetanilide, Aldesulfone sodium, Aminophenazone, Dapsone, Furazolidone, Hydralazine

MIMS Summary Table

DRUGS TO AVOID IN G6PD DEFICIENCY

DEFINITE RISK OF HAEMOLYSIS POSSIBLE RISK OF HAEMOLYSIS

Pharmacological Drugs* Pharmacological Drugs* Class Class Anthelmintics • ß-Naphthol Analgesics • Acetylsalicylic acid • Niridazole (Aspirin) • Stibophen • Acetanilide • Paracetamol G6PD Deficiency Antibiotics • Nitrofurans (Acetaminophen) - Nitrofurantoin • Aminophenazone - Nitrofurazone (Aminopyrine) • Quinolones • Dipyrone - Ciprofloxacin (Metamizole) - Moxifloxacin • Phenacetin - Nalidixic acid • Phenazone - Norfloxacin (Antipyrine) - Ofloxacin • Phenylbutazone • Chloramphenicol • Tiaprofenic acid • Sulfonamides - Co-trimoxazole Antibiotics • Furazolidone (Sulfamethoxazole + • Streptomycin Trimethoprim) • Sulfonamides - Sulfacetamide - Sulfacytine - Sulfadiazine - Sulfaguanidine - Sulfadimidine - Sulfamerazine - Sulfamethoxazole - Sulfamethoxypyridazole - Sulfanilamide Anticonvulsants • Phenytoin - Sulfapyridine - Sulfasalazine Antidiabetics • Glibenclamide (Salazosulfapyridine) - Sulfisoxazole Antidotes • Dimercaprol (BAL) (Sulfafurazole) Antihistamines • Antazoline (Antistine) • Diphenhydramine Antimalarials • Mepacrine • Tripelennamine • Pamaquine • Pentaquine Antihypertensives • Hydralazine • Primaquine • Methyldopa Antimethemo- • Methylene blue Antimalarials • Chloroquine & derivatives globinaemic Agents • Proguanil • Pyrimethamine Antimycobacterials • Dapsone • Quinidine • Para-aminosalicylic acid • Quinine • Sulfones - Aldesulfone sodium Antimycobacterials • Isoniazid (Sulfoxone) - Glucosulfone Antiparkinsonism Agents • Trihexyphenidyl - Thiazosulfone (Benzhexol) Antineoplastic Adjuncts • Doxorubicin Cardiovascular Drugs • Dopamine (L-dopa) • Rasburicase • Procainamide • Quinidine Genitourinary Analgesics • Phenazopyridine Diagnostic Agent • Toluidine blue (Pyridium) for Cancer Detection

Others • Acetylphenylhydrazine Gout Preparations • Colchicine • Phenylhydrazine • Probenecid Hormonal Contraceptives • Mestranol Nitrates • Isobutyl nitrite Vitamin K Substance • Menadiol Na sulfate • Menadione • Menadione Na bisulfite • Phytomenadione Vitamins • Ascorbic acid (Vit C) (rare) Others • Arsine • Berberine (in Coptis chinensis) • Fava beans • Naphthalene (in mothballs) • Para-aminobenzoic acid *Nomenclature based on INN (International non-proprietary name) Refer to www.g6pd.org for further information. Please refer to the Contents page for more Summary Tables.