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1 1½ - 2½ - 6 ml 25 ml 25 ml 1 1 10 ml 2 - 5 ml 18 ml 18 ml 1 ¾ 7.5 ml 1½ 15 ml 3 ml 12 ml 12 ml - ½ 5 ml 1 10 ml 2 ml 8 ml 8 ml see Chapter 5, management of the child with malaria see Chapter 5, management of the child with malaria see Chapter 5, management of the child with malaria Dose according to body weight (calculate if is below or over) - ¼ 2.5 ml ½ 5 ml 1 ml 4 ml 4 ml 3-6 kg3-6 6-10 kg 10-15 kg 15-20 kg 20-29 kg ANNEX 4: DRUG DOSAGES FOR CHILDREN (FORMULARY) Form chewable tablet, 400mg tablet, 200mg tablet/capsule 250 mg oral suspension, 125mg/5ml tablet/capsule 250 mg oral suspension, 125mg/5ml Vial of 500 mg mixed with 2.1 ml sterile water to give 500 mg/2.5 ml injection, 40mg/ml in 1ml ampoule injection, 80mg/ml in 1ml ampoule tablet 10+120 mg vial of 60 mg in 0.6 ml with 3.4 water or saline to give 60 mg/4 ml vial of 60 mg in 0.6 ml with 3.4 water or saline to give 60 mg/4 ml tablet, 50mg tablet, 50mg vial of 1.2 million units in 4 ml vial of 600 mg mixed with 9.6 ml sterile water to give 600 mg /10 ml vial of 1 g mixed with 9.6 ml sterile water to give 1 g/10 ml oral 4 mg/kg/day for 3 days 25 mg/kg 2 times per day for 3 days : IV or IM 2.4 mg/kg over 3 minutes at 0, 12 and 24 combined with , - or . IM 1.2million units over 5 years, 0.6 million below years IM 60 mg/kg/6 hours IM IV 50-100 mg/kg for 2 to 5 days 200 mg (half tablet) 12-24 months 400 mg (one tablet) over 24 months 10 mg base/kg/3 days (total dose 30 base/kg) 15 mg/kg/dose for 7 days non-severe pneumonia: IM 50 mg/kg/6 hours IM 3.2 mg/kg once on day 1 then IM 1.6 mg/kg daily until oral therapy is possible, total one week fixed dose treatment (20+120 mg) twice daily for 3 days severe malaria hours on day 1. then continue with 2.4 mg/kg over 3 minutes on day 2 until oral therapy is possible If/when possible change to oral 2 mg/kg total treatment one week. uncomplicated malaria falciparum: amodiaquine amoxicillin ampicillin artemether + benzathine benzylpenicillin benzylpenicillin ceftriaxone MedicinesDosage 95 96

MANUAL FOR THE HEALTH CARE OF CHILDREN IN EMERGENCIES

Medicines Dosage Form Dose according to body weight (calculate if weight is below or over) 3-6 kg 6-10 kg 10-15 kg 15-20 kg 20-29 kg

charcoal, activated under 1 year 1 g/kg, over 1 year, 25-50 g/kg tablets IM 25 mg/kg/6 hours maximum dose 1 g vial 1 g/ 10 ml Calculate exact quantity required: 0.25 ml contains 25 mg oral 50 mg/kg every 8 hours capsule, 250 mg - - 1 1½ 2 oral suspension, 150 mg/5 ml 3-5 ml 6-9 ml 10-14 ml 15-19 ml - chlorhexidine cetrimide 20 ml made up to 1 ll with clean water solution, 5% for dilution solution 10 mg base once daily for 2 days then 5 mg base/kg on day 3 (in tablet, 100mg, Day 1 and 2 ½ 1 1½ 2 2½ chloroquine-sensitive areas) Day 3 ½ ½ ½ 1 1 tablet, 150mg Day 1 and 2 - ½ 1 1½ 1½ Day 3 - ½ ½ 1 1 syrup, 50mg/5ml Day 1 and 2 5 ml 7.5 ml 15 ml - - Day 3 2.5 ml 5 ml 10 ml - - oral 15 mg/kg twice daily for 5 days tablet 100 mg ½ 1 ½ 2 3 oral 5mg/kg 3 times daily for 7 days capsule, 150 mg - - - - 1 dexamethasone IM 0.6 mg/kg single dose vial 5 mg/ 1 ml 0.5 ml 0.9 ml 1.4 ml 2 ml 3 ml diazepam convulsions:rectal 0.5 mg/kg vial 10 mg/ 2 ml 0.4 ml 0.75 ml 1.2 ml 1.7 ml 2.5 ml NOT TO BE USED for neonates give phenobarbital! convulsions:IV 0.2-0.3 mg/kg vial 10 mg/ 2 ml 0.25 ml 0.4 ml 0.6 ml 0.75 ml 1.25 ml NOT TO BE USED for neonates give phenobarbital! sedation before procedures: IV 0.1-0.2 mg/kg vial 10 mg/ 2 ml 0.1 ml 0.2 ml 0.3 ml 0.4 ml 0.6 ml dihydro + fixed dose treatment, 3 or 4 doses over 3 days piperaquin (artekin)* oral, not below 8 years capsule or tablet, 100mg erythromycin oral, 12.5 mg/kg 4 times daily for 3 days capsule or tablet, 250mg ¼ ½ 1 1 1½ ferrous sulphate + oral 3 mg Fe/kg/day oral solution 20 mg/ml iron 1 ml 1.25 ml 2 ml 2.5 ml 4 ml folic acid * oral, 1.25 mg/kg 4 times daily for 3 days tablet, 100 mg - - ¼ ¼ ¼ furosemide IV 1-2 mg/kg every 12 hours vial, 10 mg/ml 0.8 ml 1.6 ml 2.4 ml 3.4 ml 5 ml gentamicin IM 7.5 mg/kg once daily vial 10 mg/ml Calculate exact quantity required: 0.1 ml contains 7.5 mg 3 ½ 5 ml 10 ml 2 3.5 ml 1.7 ml 700-1000 ml 1000-1400 1 ¼ 2.4 ml 4.8 ml 1 1.6 ml 0.8 ml 400-700 ml 1 ¼ 1.5 ml 3 ml ¾ 1 ml 0.5 ml Calculate exact quantity required Calculate exact quantity required: 0.1 ml contains 20 mg Calculate exact quantity required: 0.05 ml contains 10 mg Dose according to body weight (calculate if is below or over) 3-6 kg3-6 6-10 kg 10-15 kg 15-20 kg 20-29 kg 200-400 ml - - 0.8 ml 1.6 ml ½ 0.5 ml 0.35 ml ANNEX 4: DRUG DOSAGES FOR CHILDREN (FORMULARY) Form aqueous solution 0.5% injectable solution 10% isotonic injectable solution 50% hypertonic oral solution chewable tablet, 100mg tablet, 250mg (as hydrochloride) oral solution 10 mg/5 ml; injection mg in 5 ml ampoule ORS solution ORS solution tablet 100 mg tablet 500 mg vial 5 ml vial 5 ml vial 200 mg/ml vial 200 mg/ml tablet, 200 mg vial 3 million units in 4 ml water vial 3 million units in 4 ml water up to two years 50-100 ml after each 10 mg/kg after 30 minutes IV or IM 20 mg/kg IM 50.000 IU/kg/day for 7 days IM 100.000 IU/kg/dayfor 7 days 1 teaspoon in litre of clean water 5 ml/kg of 10%, or 1 50% by slow push 6-24 months 10 ml, over 24 15 ml in case of poisoning for inducing vomiting and if not treated in previous 6 NB over 12 months ONLY months 100 mg 2 times per day for 3 days, or: 500 once only 25 mg/kg once(or as 15 then 12-24 hours later 10 mg/kg) NB not under 5 months! NB dosage must be calculated exactly! increase if necessary for severe oral 0.2-0.4 mg/kg 4-6 hourly, painIM 0.1-0.2 mg/kg 4-6 hourlyIV 0.05-0.1 infusion 0.005-0.01 mg/kg/hour plan A: after each loose stool: loose stool, over two years 100-200 ml plan B: first 4 hours 10-15 mg/kg, up to 4 times per day IM 0.2 mg/kg max 10 mg rectally 0.4 ml/kg (with blunt syringe) convulsions: if convulsions continue: oral, 20 mg/kg (max 300 mg) 4 times daily for 5 days burns: stridor: gentian violet (methylrosanilinium chloride) glucose (dextrose) Ipecacunaha, pediatric mebendazole mefloquine morphine oral rehydration salts (ORS) oxygen paracetamol paraldehyde* phenobarbital pivmecillinam* procaine penicillin benzylpenicillin MedicinesDosage 97 98

MANUAL FOR THE HEALTH CARE OF CHILDREN IN EMERGENCIES

Medicines Dosage Form Dose according to body weight (calculate if weight is below or over) 3-6 kg 6-10 kg 10-15 kg 15-20 kg 20-29 kg

total max one week, oral preferred, minimal 3 IV doses before changing to oral medication loading dose: IV 20 mg salt/kg over 4 hours once in 5-10 % vial 150 mg/ml 0.6 ml 1.2 ml 2 ml 2.4 ml 4 ml dextrose or 0.9% saline to 10 ml/kg maintenance doses: IV 10 mg salt/kg over 4 hours three times daily 0.3 ml 0.6 ml 1 ml 21.2 ml 2 ml for 4 days in 5-10 % dextrose or 0.9% saline to 10 ml/kg maintenance dose: oral 10 mg salt/kg three times daily tablet 300 mg - - ½ ½ 1 Ringer’s lactated 20 ml/kg, maximum two times 20 ml bolus severe dehydration : injectable solution solution under 1 year 100 ml of which 30 ml in first hour, rest over 5 hours, over 1 year up to 5 years total 100 ml of which 30 ml in 30 minutes then rest on 2.5 hours salbutamol if child wheezes or coughs at night 1 puff (demonstrate proper use to inhalation (aerosol), 100micrograms (as caregiver) sulfate) per dose silver topical preparation for burns cream 1% in 500 g container sodium chloride (saline) injectable solution, 0.9% isotonic (equivalent to Na+ 154mmol/l, Cl- 154mmol/l) + oral PCP prophylaxis (cotrimoxazole) eye ointment eye ointment, 1% (hydrochloride) vitamin A (retinol) 50.000 IU under 6 months, 100.000 IU over 6 months 200.000 IU tablet 50.000, 100.000 or 200.000 units over 2 years and adults measles two doses, on day 1 and 2 malnutrition one dose on day 1 vitamin K (menadion)* according to national guidelines vial 1 or 2 mg/ml zinc sulfate 10 mg/day under 6 months 20 mg/day over 6 months tablets, 20 mg