Psychedelics Again
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Nietzsche and Psychedelics – Peter Sjöstedt-H –
Antichrist Psychonaut: Nietzsche and Psychedelics – Peter Sjöstedt-H – ‘… And close your eyes with holy dread, For he on honey-dew hath fed, And drunk the milk of Paradise.’ So ends the famous fragment of Kubla Khan by the Romantic poet, Samuel Taylor Coleridge. He tells us that the poem was an immediate transcription of an opium-induced dream he experienced in 1797. As is known, the Romantic poets and their kin were inspired by the use of psychoactive substances such as opium, the old world’s common pain reliever. Pain elimination is its negative advantage, but its positive attribute lies in the psychedelic (‘mind- revealing’)1 state it can engender – a state described no better than by the original English opium eater himself, Thomas De Quincey: O just and righteous opium! … thou bildest upon the bosom of darkness, out of the fantastic imagery of the brain, cities and temples, beyond the art of Phidias and Praxiteles – beyond the splendours of Babylon and Hekatómpylos; and, “from the anarchy of dreaming sleep,” callest into sunny light the faces of long-buried beauties … thou hast the keys of Paradise, O just, subtle, and mighty opium!2 Two decades following the publication of these words the First Opium War commences (1839) in which China is martially punished for trying to hinder the British trade of opium to the Chinese people. Though opium, derived from the innocent garden poppy Papavar somniferum, may cradle the keys to Paradise it also clutches the keys to Perdition: its addictive thus potentially ruinous nature is commonly known. Today, partly for these reasons, opiates are mostly illegal without license – stringently so in their most potent forms of morphine and heroin. -
Enzymatic Encoding Methods for Efficient Synthesis Of
(19) TZZ__T (11) EP 1 957 644 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: C12N 15/10 (2006.01) C12Q 1/68 (2006.01) 01.12.2010 Bulletin 2010/48 C40B 40/06 (2006.01) C40B 50/06 (2006.01) (21) Application number: 06818144.5 (86) International application number: PCT/DK2006/000685 (22) Date of filing: 01.12.2006 (87) International publication number: WO 2007/062664 (07.06.2007 Gazette 2007/23) (54) ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES ENZYMVERMITTELNDE KODIERUNGSMETHODEN FÜR EINE EFFIZIENTE SYNTHESE VON GROSSEN BIBLIOTHEKEN PROCEDES DE CODAGE ENZYMATIQUE DESTINES A LA SYNTHESE EFFICACE DE BIBLIOTHEQUES IMPORTANTES (84) Designated Contracting States: • GOLDBECH, Anne AT BE BG CH CY CZ DE DK EE ES FI FR GB GR DK-2200 Copenhagen N (DK) HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI • DE LEON, Daen SK TR DK-2300 Copenhagen S (DK) Designated Extension States: • KALDOR, Ditte Kievsmose AL BA HR MK RS DK-2880 Bagsvaerd (DK) • SLØK, Frank Abilgaard (30) Priority: 01.12.2005 DK 200501704 DK-3450 Allerød (DK) 02.12.2005 US 741490 P • HUSEMOEN, Birgitte Nystrup DK-2500 Valby (DK) (43) Date of publication of application: • DOLBERG, Johannes 20.08.2008 Bulletin 2008/34 DK-1674 Copenhagen V (DK) • JENSEN, Kim Birkebæk (73) Proprietor: Nuevolution A/S DK-2610 Rødovre (DK) 2100 Copenhagen 0 (DK) • PETERSEN, Lene DK-2100 Copenhagen Ø (DK) (72) Inventors: • NØRREGAARD-MADSEN, Mads • FRANCH, Thomas DK-3460 Birkerød (DK) DK-3070 Snekkersten (DK) • GODSKESEN, -
(Title of the Thesis)*
Dionysian Semiotics: Myco-Dendrolatry and Other Shamanic Motifs in the Myths and Rituals of the Phrygian Mother by Daniel Attrell A thesis presented to the University of Waterloo in fulfillment of the thesis requirement for the degree of Master of Arts in Ancient Mediterranean Cultures Waterloo, Ontario, Canada, 2013 © Daniel Attrell 2013 Author’s Declaration I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. ii Abstract The administration of initiation rites by an ecstatic specialist, now known to western scholarship by the general designation of ‗shaman‘, has proven to be one of humanity‘s oldest, most widespread, and continuous magico-religious traditions. At the heart of their initiatory rituals lay an ordeal – a metaphysical journey - almost ubiquitously brought on by the effects of a life-changing hallucinogenic drug experience. To guide their initiates, these shaman worked with a repertoire of locally acquired instruments, costumes, dances, and ecstasy-inducing substances. Among past Mediterranean cultures, Semitic and Indo-European, these sorts of initiation rites were vital to society‘s spiritual well-being. It was, however, the mystery schools of antiquity – organizations founded upon conserving the secrets of plant-lore, astrology, theurgy and mystical philosophy – which satisfied the role of the shaman in Greco-Roman society. The rites they delivered to the common individual were a form of ritualized ecstasy and they provided an orderly context for religiously-oriented intoxication. -
Daniel Bovet
D ANIEL B OVET The relationships between isosterism and competitive phenomena in the field of drug therapy of the autonomic nervous system and that of the neuromuscular transmission Nobel Lecture, December 11, 1957 Putting to good use the vast possibilities which organic synthesis offers, a number of workers have directed their efforts towards applying it to thera- peutics, and have sought to establish the bases of a science of pharmaceutical chemistry, or, more exactly perhaps, the bases of a science of chemical pharmacology worthy of this name. If such an ambitious programme has not yet been fully realized, we are at least justified in recognizing, in the work which has now been in progress for fifty years, the appearance of a few guiding principles whose value has not ceased to assert itself. This is particularly true, for example, in the case of ideas in isosterism and com- petition. The origin of many drugs must be looked for in substances of a biological nature, and in particular in the alkaloids. The elucidation of their structure has been a starting-off point for chemists to synthesize similar compounds. Cocaine, atropine, and morphia are particularly good examples in this respect, since substances which are made like them have shown, clinically, local anaesthetic, antispasmodic, and marked analgesic properties, respective- ly. In each of these cases the physiological properties of the new compound seem to be similar to the compound to which it is structurally related. This has been verified in many other fields, but it is nevertheless evident that in certain cases, molecules which are chemically closely related have very dif- ferent and even antagonistic properties. -
Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances Joshua Zolton Seither [email protected]
Florida International University FIU Digital Commons FIU Electronic Theses and Dissertations University Graduate School 4-25-2018 Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances Joshua Zolton Seither [email protected] DOI: 10.25148/etd.FIDC006565 Follow this and additional works at: https://digitalcommons.fiu.edu/etd Part of the Chemistry Commons Recommended Citation Seither, Joshua Zolton, "Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances" (2018). FIU Electronic Theses and Dissertations. 3823. https://digitalcommons.fiu.edu/etd/3823 This work is brought to you for free and open access by the University Graduate School at FIU Digital Commons. It has been accepted for inclusion in FIU Electronic Theses and Dissertations by an authorized administrator of FIU Digital Commons. For more information, please contact [email protected]. FLORIDA INTERNATIONAL UNIVERSITY Miami, Florida APPLICATION OF HIGH RESOLUTION MASS SPECTROMETRY FOR THE SCREENING AND CONFIRMATION OF NOVEL PSYCHOACTIVE SUBSTANCES A dissertation submitted in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY in CHEMISTRY by Joshua Zolton Seither 2018 To: Dean Michael R. Heithaus College of Arts, Sciences and Education This dissertation, written by Joshua Zolton Seither, and entitled Application of High- Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances, having been approved in respect to style and intellectual content, is referred to you for judgment. We have read this dissertation and recommend that it be approved. _______________________________________ Piero Gardinali _______________________________________ Bruce McCord _______________________________________ DeEtta Mills _______________________________________ Stanislaw Wnuk _______________________________________ Anthony DeCaprio, Major Professor Date of Defense: April 25, 2018 The dissertation of Joshua Zolton Seither is approved. -
Abstract Book 2012.Indd
SUPPLEMENT TO JOURNAL OF PSYCHOPHARMACOLOGY VOL 26, SUPPLEMENT TO ISSUE 8, AUGUST 2012 These papers were presented at the Summer Meeting of the BRITISH ASSOCIATION FOR PSYCHOPHARMACOLOGY 22 – 25 July, Harrogate, UK Indemnity The scientific material presented at this meeting reflects the opinions of the contributing authors and speakers. The British Association for Psychopharmacology accepts no responsibility for the contents of the verbal or any published proceedings of this meeting. BAP OFFICE 36 Cambridge Place Hills Road Cambridge CB2 1NS bap.org.uk Aii CONTENTS Abstract Book 2012 Abstracts begin on page: SYMPOSIUM 1 A1 Drugs as tools in neuropsychiatry: Ketamine (S01-S04) SYMPOSIUM 2 A2 New tricks for old drugs: Opiates, addiction and beyond (S05-S08) SYMPOSIUM 3 A3 Advances in understanding brain corticosteroid responses to stress: relevance to depression (S09-S12) SYMPOSIUM 4 A5 Cognitive impairment in depression: A target for treatment? (S13-S16) SYMPOSIUM 5 A6 New treatment strategies for targeting drug addictions – A translational perspective (S17-S20) SYMPOSIUM 6 A7 Functional imaging markers for monitoring treatment: Mechanisms and efficacy (S21-S24) SYMPOSIUM 7 A9 Schizophrenia Treatment: What’s wrong with it and what might work better (S25-S28) SYMPOSIUM 8 A10 Epigenetics and psychiatry - current understanding and therapeutic potential (S29-S32) SYMPOSIUM 9 A11 Rethinking the compulsive aspects of addiction: From bench to bedside (S33-S36) POSTERS Anxiety 1 (MA01-MA07) A13 Affective Disorders 1 (MB01-MB20) A16 Brain Imaging -
Research Chemicals Und Andere Neue Drogen
Research Chemicals & andere „neue“ Drogen Impulsreferat auf der DO-Leitertagung am 08.04.2014 Dipl.-Psych. Marcus Breuer psycholog. Psychotherapeut Begriffsklärung • Crystal = Crystal Speed; kristallines Metamphetamin • ATS = Amphetamin Type Stimulants • NPS = New Psychoactive Substances • Badesalze = Szenebezeichnung, denkbar ungeeignet, weil sie nichts erklärt und außerdem verharmlost • Research Chemicals = diese Stoffe sind „Abfallprodukte“ aus der Medikamentenentwicklung oder aber gezielte Veränderungen bekannter psychoaktiver Substanzen • Legal Highs = viele dieser neuen Stoffe sind bzw. waren zunächst legal (nicht dem BtmG unterstellt) • Kräutermischungen = Spice & Co., rauchbare synthetische Cannabinoide (viel toxischer als Cannabis) Wirkbogen der Partydrogen Entaktogene Ecstasy-MDMA MDEE Häufigkeit • ATS= Amphetamine Type Stimulants • Amphetamin (Speed) • XTC (MDMA; MDE; MDA) • Methamphetamin (Crystal) • Weltweit zusammen 26 million “regular users” vs: • Kokain 14 million reg. users • Heroin 16 million reg. users Nach WHO and UNODOC-Schätzungen (2010) ist Methamphetamin weltweit alleine die nach CANNABIS am häufigsten konsumierte illegale Substanz(18 Mio) (Nikotin und Alkohol sind Hauptproblem…..) Gesamtzahlen erstauffällige Konsumenten nach BKA: Trend 2000-2009 Drogentrends Exkurs: Research Chemicals I Neue Clubdrugs/Trenddrogen - fast alles RC-Drugs: • Substanzen, die zu Forschungszwecken genutzt werden und als solche „gekauft“ werden…. • RC-Substanzen (research chemicals) / Designerdrugs….. • Zeitweise nicht dem BTMG der jeweiligen -
Pharmacology Notebook 1 PDF (Searchable)
The Shulgin Lab Books December 2012 May 2018 Pharmacology Lab Notes #1 (1960 - 1976) A Bit About This Document: While undertaking the work of investigating the chemistry and pharmacology of many varied psychoactive substances, Alexander “Sasha” Shulgin kept detailed notebooks. His documentation covered not only on his own personal research, but the research of friends and acquaintances. This book, the first of the “Pharmacology” series, represents mostly sub-acute work-ups of various substances and subjective responses by Shulgin and his research group. It covers the time frame of 1960 to 1976. The Creation of This Document: The project to undertake the transcribing of Shulgin’s Lab Books was started in 2008 by a team of volunteers and staff at Erowid, along with members of Team Shulgin. Various books were transcribed without a clear idea of how to present the information as a final product; eventually this format was chosen and a volunteer began work assembling the document. Each page was painstakingly transcribed from scanned images. All the hand-drawn “dirty pictures” (molecule drawings) and graphs were edited from the original scans and combined with drawn-in marks, outlines, and arrows to form this searchable PDF. Most of the names in this document have been redacted and pseudonyms put in their place. Names are presented as much as possible as they were in the original book, for example “Robert Thompson” is also “Robert”, “R.Thompson”, and “RT”. Initials are frequently used, and no two people share names or initials so the reader can keep track of who’s who. Words highlighted in yellow are words that the transcription team could not decipher. -
Psychedelic Review
The PSYCHEDELIREVIEWC Vol. I June1963 No.1 C_ntents Editorial ............................................... S Statement of Purpose .................................... S "CAN THIS DRUG ENLARGE MAN'S MIND?" ...................... Gerald Heard ? THE SUBJECTIVE AFTER-EFFECTS OF PSYCHEDELIC EXPERIENCES: A Summary of Four Recent Questionnaire Studies .............. The Editors 18 THE HALLUCINOGENIC FUNGI OF MEXICO: An Inquiry Into The Origins of The Religious Idea Among Primitive Peoples ............ R. Gordon Wasson · $7 A TOUCHSTONE FOR COURAGE ................ Plato 43 PROVOKED LIFE: An Essay on the Anthropology of the Ego .............................. Gott[ried Bean 47 THE INDIVIDUAL AS MAN/WORLD... Alan W. Watts 55 ANNIHILATING ILLUMINATION ..... George Andrews 66 THE PHARMACOLOGY OF PSYCHEDELIC DRUGS .............................. Ralph Metgner 69 Notes on Contributors .................................... 11G x.. 877"' Journey to the East, Western philosophers have written of experi- ences which go beyond our everyday shadowy perception and disclose with startling force a direct vision of reality. The quest for this ex- perience and the awareness of its implications is far more highly EDITORIAL developedin the East than in the West; hence the program has often been stated in terms of unifying the Eastern and Western approaches. The age-old issue of freedom versas control has entered a new Discerning men have stressed over and over that we have much to stage in our era. Many critics have described and denounced the pre- learn from the two great cultures of the East: India with its highly vailing external control of our activities and resources, and particu- differentiated practical understanding of different states of conscious- larly the ideological indoctrination and psychological manipulation ness; and China with its superbly developed sensitivity to the corn- to which we are subject through the mass media. -
Ayahuasca's Religious Diaspora in the Wake of the Doctrine of Discovery
University of Denver Digital Commons @ DU Electronic Theses and Dissertations Graduate Studies 2020 Ayahuasca’s Religious Diaspora in the Wake of the Doctrine of Discovery Roger K. Green University of Denver Follow this and additional works at: https://digitalcommons.du.edu/etd Part of the Ethics in Religion Commons, History of Religions of Western Origin Commons, Indigenous Studies Commons, Latin American Studies Commons, Missions and World Christianity Commons, and the Other Religion Commons Recommended Citation Green, Roger K., "Ayahuasca’s Religious Diaspora in the Wake of the Doctrine of Discovery" (2020). Electronic Theses and Dissertations. 1765. https://digitalcommons.du.edu/etd/1765 This Dissertation is brought to you for free and open access by the Graduate Studies at Digital Commons @ DU. It has been accepted for inclusion in Electronic Theses and Dissertations by an authorized administrator of Digital Commons @ DU. For more information, please contact [email protected],[email protected]. Ayahuasca’s Religious Diaspora in the Wake of the Doctrine of Discovery __________ A Dissertation Presented to the Faculty of the University of Denver and the Iliff School of Theology Joint PhD Program University of Denver __________ In Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy ___________ by Roger K. Green June 2020 Advisor: Carl Raschke ©Copyright by Roger K. Green 2020 All Rights Reserved Author: Roger K. Green Title: Ayahuasca’s Religious Diaspora in the Wake of the Doctrine of Discovery Advisor: Carl Raschke Degree Date: June 2020 Abstract ‘Ayahuasca’ is a plant mixture with a variety of recipes and localized names native to South America. -
Night Life in Europe and Recreative Drug Use. SONAR 98
Night life in Europe and recreative drug use. SONAR 98 Authors: Amador Calafat, Karl Bohrn, Montserrat Juan, Anna Kokkevi, Nicole Maalsté, Fernando Mendes, Alfonso Palmer, Kellie Sherlock, Joseph Simon, Paolo Stocco, Mª Pau Sureda, Peter Tossmann, Goof van de Wijngaart, Patricia Zavatti Nigut life in Europe and recreative drug use. SONAR and recreative Nigut life in Europe 98 Financed with the assistance of the EUROPEAN COMMISSION IREFREA IREFREA IREFREA is a european network interested in the promotion and research of primary prevention of different sorts of juvenile malaise and the study of associated protective and risk factors. NIGHT LIFE IN EUROPE AND RECREATIVE DRUG USE. SONAR 98 Research Coordinator: Amador Calafat 3 NIGHT LIFE IN EUROPE AND RECREATIVE DRUG USE. SONAR 98 Authors: Amador Calafat, Karl Bohrn, Montserrat Juan, Anna Kokkevi, Nicole Maalsté, Fernando Mendes, Alfonso Palmer, Kellie Sherlock, Joseph Simon, Paolo Stocco, Mª Pau Sureda, Peter Tossmann, Goof van de Wijngaart, Patrizia Zavatti Collaborators: Susanne Ebner (Vienna); Laura de Fazio (Modena); Alan Haughton (Manchester); Lucia Mariano (Coimbra); Claudia Pilgrim (Berlin); Jérome Reynaud (Nice); Ioanna Siamou (Athens); Rebecca Simpson (Manchester); Sabine Tyrväinen (Vienna); Erika Van Vliet (Utrecht) IREFREA Financed with the assistance of the EUROPEAN COMMISSION NEITHER THE COMMISSION, NOR ANY PERSON ACTING IN ITS NAME, IS RESPONSIBLE FOR THE USE THAT MIGHT BE MADE OF THE INFORMATION INCLUDED IN THIS DOCUMENT ORGANISATIONS, INSTITUTIONS AND NATIONAL RESEARCH GROUPS PARTICIPATING IN THIS RESEARCH IREFREA DEUSCHTLAND CSST / CREDIT Horst Brömer Joseph Simon Drogenhilfe Tannehof Berlin e v 10, Av. Malausséna. 06000 Nice (France) Wilhelmsaue, 116. 10715 Berlin Tel:+330493926321 - Fax: +330493026320 tel +49307440213 - Fax: +493076403229 E-mail: [email protected] [email protected] INSTITUTE SOZIAL UND GESUNDHERST IREFREA - ESPAÑA Karl Böhrn Amador Calafat, Montse Juan, Mª Pau Sureda Pladenhanergasse, 20/1. -
Reproductions Supplied by EDRS Are the Best That Can Be Made from the Original Document
DOCUMENT RESUME ED 450 312 CG 030 735 TITLE Annual Report on the State of the Drugs Problem in the European Union, 2000. INSTITUTION European Monitoring Centre for Drugs and Drug Addiction, Lisbon (Portugal). ISBN ISBN-92-9168-097-4 PUB DATE 2000-00-00 NOTE 44p. AVAILABLE FROM For full text: http://www.emcdda.org. PUB TYPE Information Analyses (070) Numerical/Quantitative Data (110) EDRS PRICE MF01/PCO2 Plus Postage. DESCRIPTORS Children; Cocaine; Communicable Diseases; Crime; Death; *Drug Education; Foreign Countries; Heroin; Marijuana; Policy; Prevention; Substance Abuse; *Trend Analysis IDENTIFIERS Amphetamines; Ecstasy (Drug); *European Union ABSTRACT This report presents an overview of the drug phenomenon in Europe at the start of the new millennium. The first chapter begins with a discussion of overall drug trends. Specifically, it examines trends in drug use and the consequences including multiple drug use; problem drug use and demand for treatment; drug-related deaths; drug-related infectious diseases; and other morbidity. A discussion of the trends in response to drug use looks at policy and strategy development; prevention; reducing the harmful consequences of drug use; and treatment. Chapter two discusses the prevalence and patterns of drug use. Health consequences of drug use, law-enforcement indicators, and drug-market indicators (seizures, price, and purity) are covered in this chapter. The third chapter explains policy and strategy developments as well as demand-reduction responses as they relate to the drug use problem. Chapter four examines substitution treatment, prosecution of drug-related offenses, and problems facing women drug users and their children. The final chapter discusses the drug problem in Central and Eastern Europe.