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Front Matter (PDF) aien @J?ess CARCINOGENESIS: A COMPREHENSIVE SURVEY PROGRESS IN CANCER RESEARCH AND THERAPY Volume 4: Nitrofurans Volume 9: Endocrine Control in Neoplasia G. Bryan, editor R. K. Sharma and W. E. Criss, editors This volume surveys the chemistry, metabolism, mutagenici The 38 chapters in this volume, by leading authorities in the ty, activation, and carcinogenicity of nitrofurans, a group of field, focus on the mode of action of hormones in carcino drugs that are carcinogenic for a variety of mammals. genesis and tumor development, and include the most recent 248 pages, $19.50 (1978) studies concerning hormonal responsiveness in a dozen forms of cancer. Volume 3: Polynuclear Aromatic Hydrocarbons: 381 pages,$32.00 (1978) t Second International Symposium on Volume 8: Polyamines as Biochemical Markers of Normal Analysis, Chemistry, and Biology and Malignant Growth P. W. Jones and R. I. Freudenthal, editors D. H. Russelland B. G. M. Dune This volume reviews our understanding of the factors that This monograph provides clinicians with a treatise that de influence polynuclear aromatic hydrocarbon formation, tails the role of polyamines as biochemical markers of suc high-sensitivity techniques for the measurement of these cess and failure in cancer chemotherapy. widespread environmental contaminants, and their metabolit 198 pages,$17.50 (1978) ic conversion to biologically active metabolites. 512 pages, $39.50 (1978) Volume 5: Cancer Invasion and Metastasis: Biologic Mechanisms and Therapy Volume 2: Mechanisms of Tumor Promotion and S. B. Day, W. P. L. Myers, P. Stansly, Cocarcinogenesis S. Garattini, and M. G. Lewis, editors Thomas J. Slaga, R. K. Boutwell, In this important new volume, leading researchers in the and Andrew Sivak, editors field of metastasis control present an up-to-date account of the current status of this crucial research area. @ : This volume presentsthe results supporting the generality @ ) of the sequential nature of biological events in carcinogenesis, 540 pages,$35.00 (1977) @ ., 3 and is directed to all scientists interested in better under Volume 3: Genetics of Human Cancer • •(@ standing the induction of cancer. J. J. Mulvihill, R. W. Miller, and J. F. Fraumeni, Jr., editors @LI@ 646 pages $4500 (1978) This volume examines cancer in special populations, and in cludes a discussion of population genetics. Approximately 200 single gene traits that involve neoplasia are described L RANDOMIZED TRIALS IN CANCER: A CRITICAL and the applications of the concepts of population and REVIEW BY SITES (European Organization for Research clinical genetics to a more basic understanding of carcino on Treatment of Cancer (EORTC) Monograph Series, Vol. 41 genesis are discussed. M. Staquet, editor 541 pages,$22.50 (1977) This is the first volume ever published to review the entire Prices higher outside the U.S.A. and Canada. subject of randomized clinical trials in cancer therapy. More than 20 different kinds of human cancer are discussed. ORDER FORM 448 pages,$36.00 (1978) Please send: — CHORIOCARCINOMA AND RELATED GESTATIONAL TROPHOBLASTIC TUMORS IN WOMEN @ Roy Hertz ,@ @i1 In this monograph the author presents the concept of tro o To save postage and handling charges, I enclose payment (or V phoblastic neoplasia as a biologically continuous spectrum charge my credit card below). N.Y. residents add 8% sales tax. consisting of the clinical entities of hydatidiform mole, in o Charge my credit card no.: vasive mole, and choriocarcinoma. This comprehensive pre I Circle one: American Express BankAmericard (Visa) sentation covers salient features of trophoblastic disease ‘.,ith Diners Club Master Charge (4-digit no.: respect to epidemiology, pathogenesis, and treatment. Card expiration date: 150 pages,$15.00 (1978) Name (please print): I Address: i@(@RavenPressMailyourorderto: 114OAVENUEOFTHEAMERICASI NEW@YORKNEWYORK10036C98 .. @ , —@-@----@ —i r-@j-@-----@ i___— :::@@ ;— o;:— @r @.) @-@- I @@_________ ____ ________________________ _______ @ @-@‘e@w @- COVER LEGEND. area. The Institute has had four directors: Gaetano Fichera (1928-1935); Pietro Rondoni (1935-1 956); Pietro Bucalossi (1957-1975); and Umberto Veronesi (1975—present). Among its main contributions have been work on daunomycin and Adriamycin, adjuvant chemo therapy of breast cancer, and non-Hodgkin's lymphoma and melanoma. The Istituto di Richerche Farmacologiche “MarioNegri―was founded in 1960and began @ @--@—-@ its activities in 1963, under the legacy of a Milanese philanthropist who died of cancer. It is devoted to research in cancer chemother apy, neuropsychopharmacology, and cardio vascular pharmacology, and it consists of 18 laboratory units with a total of 300 workers. The Institute is headed by Silvio Garattini. Some of its main contributions have been on development of models to study metastases in experimental animals and characterization of Cancer Research this month salutes two immu nostim ulants and immunodepressants. outstanding cancer institutions in Milan, Italy. It has issued numerous monographs such as lstituto Nazionale per lo Studio e Ia Cura dei Chemotherapy of Cancer Dissemination and Tumori of Milan was founded in 1928. Its Metastases (New York: Raven Press, 1973). present structure includes two divisions of Pictured: above, Istituto Nazionale, and Pro experimental oncology and six divisions of fessor Veronesi; below, Istituto Mario Negri, clinical oncology, comprising a comprehen and Professor Garattini sive cancer center with 510 beds in its hospital M.B.S..
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