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Pre-Feasibility Report PRE-FEASIBILITY REPORT Synthetic Organic Chemicals 5(f) M/s Infinium Pharmachem Pvt. Ltd. Plot No:- 37, 38 & 39, GIDC Sojitra, Dist: ANAND (Gujarat). OCTOBER 2016 Prepared by: EXCEL ENVIRO TECH (NABET Accredited EIA Consultant Organization) TF-2 , SUN HOUSE, Near Old High Court Off Ashram Road, Ahmedabad – 380 009 Tele-fax: 079–27542219 Cell: +91-98255 88910 Email: [email protected] Website : www.excelenviro.com INFINIUM PHARMACHEM PVT. LTD Feasibility Report PA TABLE OF CONTENTS GE7 CHAPTER 1 INTRODUCTION TO THE PROJECT 213 1.1 Project PROPONENTs 2 CHAPTER 2 PROJECT DESCRIPTION 3 2.1 Project Location 3 2.2 Alternate Sites Considered 3 2.3 Products & Raw Material Details 5 2.4 Manufacturing Process 9 2.5 Details of Air Pollution Management 159 2.6 Details water and wastewater 159 2.7 Utilities Requirement 160 2.8 Manpower Requirement 161 CHAPTER 3 SITE ANALYSIS 161 3.1 Connectivity 161 3.2 Existing Landuse Pattern 161 3.3 Topography 161 3.4 Social Infrastructure Available: 162 3.5 Rehabilitation & Resettlement Plan 162 3.6 Landuse Breakup 162 CHAPTER 4 PROPOSED ENVIRONMENTAL INFRASTRUCTURE 163 4.1 Management of Domestic Waste Water 163 4.2 Management of Industrial Waste Water 163 4.3 Air Quality Management: 164 4.4 Solid & Hazardous Waste Management 164 4.5 Hazardous Chemicals Details 165 4.6 Waste Minimization Measures 165 ANNEXURE 166 EC COPY 168 CC&A COPY 173 GIDC Letter 178 NECL Certificate(hazardous waste) 180 NECL Certificate(Incineration) 181 Plant layout 182 1 INFINIUM PHARMACHEM PVT. LTD Feasibility Report CHAPTER 1 PA GE7 13 INTRODUCTION TO THE PROJECT M/s. Infinium Pharmachem Pvt. Ltd is a Small scale unit established in 2009. Infinium pharmachem is India based pharmaceutical intermediates manufacturer which is extremely effective, efficient and professionally managed organization. The company also undertakes contract manufacturing for many products. It can give the assurance of timely delivery, excellent quality and competitive rates. And that is what they call as our core competence at Infinium Pharmachem Pvt. Ltd. They welcome importers, distributors and agents who help to introduce products on their national markets Infinium Pharmachem Pvt. Ltd provides comprehensive range of services as well as prompt and reliable assistance for all their customers around the world Product Range from Infinium Pharmachem Pvt. Ltd. Each and every functional area of organization is led by professionally qualified people who had thorough understanding and experience into that particular area. That is the way how they keep tab on qualitative measures by qualified people, thoroughly. 1.1 PROJECT PROPONENTS Infinium pharmachem Pvt. Ltd is a Private Limited Company launched by Mr. Sanjay V. Patel, Mr. Mitesh Lavajibhai Chikhaliya & Mr. Pravin Bhadabhai Madhani. Directors are young, dynamic and enthusiastic to lead the task towards completeness. Currently, the managerial team includes 4 administrative and 10 working staff. For proposed expansion/diversification activity, more 6 people may get employed at full capacity production. 2 INFINIUM PHARMACHEM PVT. LTD Feasibility Report CHAPTER 2 PA GE7 PROJECT DESCRIPTION 13 2.1 PROJECT LOCATION The Project is located at coordinates 22o31’48’’N 72o42’55’’E in, GIDC Sojitra, Ta-Sojitra, Anand. Plot No: 37, 38 & 39 about 20.0 km far from Anand railway station and 55 km far from Vadodara Airport. The Plant is 600 m away from State Highway (SH-83) that provides a convenient & competitive trade gateway to domestic market transportation. Location Of The Project With Surroundings 2.2 ALTERNATE SITES CONSIDERED The company has not considered any alternate site as it already has an existing plant for manufacturing of Inorganic Iodine Derivatives at the site. Necessary permissions from State Pollution control Board for the same have been obtained. The proposed products are value addition to the existing products (being organic Iodine Derivatives). As the unit is located in notified area of GIDC, the site is having all required infrastructure facilities in form of; water, electricity, and Road available for the existing as well as proposed activities. 3 INFINIUM PHARMACHEM PVT. LTD Feasibility Report PA GE7 13 Location of site within 500 m Radius Location of site within 5-km Radius 4 INFINIUM PHARMACHEM PVT. LTD Feasibility Report 2.3 PRODUCTS & RAW MATERIAL DETAILS Product Details PA GE7 The Details of existing and proposed products are given in following table:13 Quantity Name of the products (MT/Month) Existing Products Potassium Iodide 50 MT/Month Sodium Iodide Ammonia Iodide, Copper Iodide, Zinc Iodide, Calcium Iodate, Potassium Iodate, Sodium Meta Proposed Products per Iodate Inorganic Iodine Derivatives (1)Sodium Iodide, (2)Potassium Iodide, (3) Ammonium Iodide, (4) Copper Iodide, (5) Zinc Iodide, (6)Silver Iodide, (7)Calcium Iodate, (8) Potassium Iodate, (9)Soidum Iodate, (10)Sodium Meta Par Iodate, (11) Lithium Iodide Hydrate, (12)Nickel Iodide, (13) Lead Iodide, (14) Cadmium Iodide, (15)Thallium Iodide, (16)Antimony Iodide, (17)Hydroiodic Acid, (18)Calcium Iodide Hydrate, (19) Iodine, (20)Iodine Monochloride, (21) Iodine 0.1N Standard 50 MT/Month Solution, (22) Cesium Iodide, (23) Iodine Monochloride Solution In Acetic Acid, (24) Iodine Monochloride Solution In MDC, (25)Barium Iodide Dihydrate, (26) Iodic Acid (Solution), Organic(27)Iodic Iodine Acid (Crystal), Derivatives(28)Per-Iodic Acid (1)Iodobenzene Diacetate, (2)Bis Trifluoro Acetoxy Iodobenzene, (3)4-Iodobenzoicacid, (4) 3- Iodobenzoic Acid, (5)Methyl Tri Phenyl Phosphonium Iodide, (6) Ethyl Tri Phenyl Phosphonium Iodide, (7) Iso Propyl Tri Phenyl Phosphonium Iodide, (8) 1-Iodohexane, (9)1- Iodoheptane, (10)Cyclo Hexyliodide, (11)4-Iodoaniline, (12) 2-Fluoro -4-Iodoaniline, (13)1, 4 – Diiodobenzene, (14)4 – Iodophenol, (15)2 – Iodotoluene, (16)3 , 5 – Diiodosalicylicacid, (17) 1,3-Diiodo-5,5-Dimethyl Hydantoin, (18)N-Iodo Succinimide, (19) 2 – Iodophenol, (20)Iodoform, (21) Tetrabutyl Ammonium Iodide, (22)Trimethyl Sulfoniumiodide, (23) Chloroiodomethane, (24) Di Iodo Methane, (25) Ethyl Magnesium Iodide - 1M Solution In 50 MT/month THF, (26) Methyl Magnesium Iodide - 1M Solution In THF, (27)Thymol Iodide, (28) 1,3 – Diiodopropane, (29) 1 , 10-Diiododecane, (30)2-Iodoethanol, (31) 1-Bromo 2-Iodobenzene, (32) 1-Bromo 4-Iodobenzene, (33) 3-Iodo-N-Phenyl Carbazole, (34)4-Fluoro Iodobenzene, (35) 2-Nitro Iodobenzene, (36) 2-Iodo Aniline, (37) 2-Butyl-3(3,5-Diiodo-4-Hydroxy Benzoyl) Benzofuran, (38)Methyl Ammonium Iodide, (39) 1,3-Diiodo Benzene, (40) 5-Iodo Uracil, (41) 1,4-Diiodo Butane, (42)2-Iodoacetic Acid, (43)3- Iodo Pyridine, (44)4- Iodo Pyridine, Total(45)Iodophor, (46)Povidone – Iodine Powder, (47)Diiodoethane, (48)6- Iodo Indazole, (49)4- Bromo-2-Iodoaniline, (50) 3-Iodoaniline PRODUCTS TO BE AMENDED 150 MT/month Inorganic Iodine Derivatives Organic Iodine Derivatives (1)Potassium Metaper Iodate (1)Methyl Iodide, (2)Ethyl Iodide, (3)1-Iodo Propane, (4)2-Iodopropane, (5)1-Iodo Butane, (6A)Allyl Iodide(Hydriodic Acid Route) (6B)Iodine Route, (7)Trimethyl Sulfoxonium Iodide, (8)Iodo Benzene, (9)3-Iodo Toluene, (10)2-Iodo Methyl Benzoate, (11)2-Iodo Benzoicacid, (12)Dess-Martin Periodinane, (13)3-Iodo Benzotriflouride 5 INFINIUM PHARMACHEM PVT. LTD Feasibility Report PA Raw Material Details (approx. consumption) Sr. No. Raw Material Name Consumption per monthGE7 1 1-Butanol (N-Butanol) 600 kg 13 2 1-Heptanol (N-Heptyl Alcohol) 68 kg 3 1-Propanol (N-Propyl Alcohol) 145 kg 4 1,10 Decandiol 152 kg 5 1,3-Dibromo 5,5-Dimethyl Hydentoin 154 kg 6 1,3-Dibromo Propane 77 kg 7 2-Amino Phenol 107 kg 8 2-Bromoaniline 570 kg 9 2-Butyl-3(4-Hydroxy Benzoyl)Benzofuran 1090 kg 10 2-Chloroethanol 150.00 kg 11 2-Fluoro Aniline 50 kg 12 2-Nitro Aniline 130 kg 13 2-Nitro Iodobenzene 276 kg 14 2-Propanol (IPA) 452 kg 15 2-Toludine 56 kg 16 3-Amino N-Phenyl Carbazole 79 kg 17 3-Amino Pyridine 52 kg 18 3-Aminobenzoic Acid 63 kg 19 3-Nitro Aniline 81 kg 20 3-Toludine 54 kg 21 3-Trifluoromethyl Aniline 70 kg 22 4-Amino Benzoic Acid 144 kg 23 4-Amino Phenol(P-Amino Phenol) 275 kg 24 4-Amino Pyridine 49 kg 25 4-Bromo Aniline 64 kg 26 4-Bromo Aniline 133 kg 27 4-Fluoroaniline 55 kg 28 40 % Monomethyl Amine 261 kg 29 6-Amino Indazole 72 kg 30 Acetic Acid 463 kg 31 Acetic Anhydride 2918 kg 32 Acetone 11280 Lit 33 Acetylene 30 kg 34 Allyl Alcohol 57 kg 35 Ammonia (NH3) 14 Lit 36 Aniline 3494 kg 37 Catalyst (AiBN) 2 kg 38 Charcoal 99 kg 39 CHLOROFORM (CHCl3) 191 Lit 40 Cyclohexane 187 kg 41 Cyclohexanol 65 kg 42 Diethyl Sulphate (DES) 817 kg 43 Dimethyl Sulphate (DMS) 11597 kg 44 Dimethyl Sulphide 295 kg 45 Dimethyl Sulphoxide (DMSO) 5217 kg 46 Ethelyne Dichloride (EDC) 3813 Lit 47 Ethyl Acetate 4509 kg 6 INFINIUM PHARMACHEM PVT. LTD Feasibility Report Sr. No. Raw Material Name Consumption per month 48 Formic Acid 4721 kg PA 49 HYDROCHLORIC ACID (HCl) 662 Lit GE7 50 Hydrogen Peroxide (H2O2) 1015 kg 13 51 Hydroiodic Acid (HI) 167 kg 52 Ice 3333 kg 53 Iodine (I2) 31991 kg 54 Iodine Monochloride 60 kg 55 Iodobenzene Diacetate 111 kg 56 Iron Powder (Fe) 43 kg 57 Magnesium Metal 15 kg 58 Meta Phenelyne Diamine 39 kg 59 Methanol (CH3OH) 16802 Lit 60 Methelyne Dichloride (MDC) 4339 kg 61 Methyl Anthranilate 937 kg 62 Monochloro Acetic Acid (MCA) 64 kg 63 N-Chlorosuccinimide (NCS) 1040 kg 64 N-HEPTANE 6971 kg 65 N-HEXANOL (N-HEXYL ALCOHOL) 61 kg 66 Phosphate Buffer (pH-7) 423 kg 67 Phosphate Buffer (Powder) 3776 kg 68 Phosphoric Acid 123 kg 69 Potassium Bromate 129 kg 70 Potassium Hydroxide(KOH) 10037 kg 71 Potassiun Iodide (KI) 3606 kg 72 Red Phosphorous 392 kg 73 Salicylic Acid 390 kg 74 Soda Ash 950 kg 75 Sodium Acetate 963 kg 76 Sodium Bicarbonate (SBC) 819 kg 77 Sodium Bisulphite (SBS) 343 kg 78 SODIUM HYDROXIDE (NaOH) 2590 kg 79 Sodium Hypochlorite (Hypo) 700 Lit 80 SODIUM IODIDE (NaI) 106 kg 81 SODIUM NITRITE(NaNO2) 420 kg 82 Sodium Sulphide 712 kg 83 Sulphuric Acid (H2SO4) 7195 kg 84 Tetrahydrofuran (THF) 666 kg 85 Thymol 555 kg 86 Toluene 7400 Lit 87 Tributyl Amine 827 kg 88 Trifluoro Acetic Acid (TFA) 111 kg 89 Triphenyl Phosphine (TPP) 472 kg 90 Uracil 53 kg 91 Water (H2o) 62575 Lit 92 Xylene 202 kg 2.4 MANUFACTURING PROCESS: 7 INFINIUM PHARMACHEM PVT.
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