CURRICULUM VITAE
JOHN STANLEY MATTICK PhD AO FAA FAHMS FRSN HonFRCPA
PERSONAL
Date of Birth: 26th April, 1950 Place of Birth: Sydney, Australia
Nationality: Australian
Current Positions: Executive Director Garvan Institute of Medical Research 384 Victoria Street, Darlinghurst Sydney NSW 2010 Australia Telephone: +61 2 9295 8120 Email: [email protected] URL: http://www.garvan.org.au Conjoint Professor, St Vincent’s Clinical School, and Adjunct Professor, School of Biotechnology & Biomolecular Sciences University of New South Wales Honorary Professor of Molecular Biology, University of Queensland
DEGREES B.Sc. (First Class Honours, Biochemistry) 1968-1971, University of Sydney Ph.D. in Biochemistry 1972-1977, Monash University, Melbourne
HONOURS AND AWARDS
• Pharmacia-LKB Biotechnology Medal, Australian Biochemical Society, 1989 • Butland Visiting Professorship, The University of Auckland, 1997 • Eppendorf Achievement / Millenium Science Award, Lorne Genome Conference, 2000 • Visiting Senior Research Fellowship, St. John’s College, Oxford, 2000 • Officer in the Order of Australia (AO), 2001 • Honorary Fellowship of the Royal College of Pathologists of Australasia (FRCPA), 2002 • Australian Government Centenary Medal, 2003 • CSIRO Eureka Prize for Leadership in Science, 2006 • Associate Membership, European Molecular Biology Organization, 2007 • Inaugural Gutenberg Chair, University of Strasbourg, 2008 • Fellowship of the Australian Academy of Science, 2008 • Julian Wells Medal, Lorne Genome Society, 2009
John Mattick CV Page 1 • International Union of Biochemistry and Molecular Biology (IUBMB) Medal, 2011 • Human Genome Organization (HUGO) Chen Award for Distinguished Achievement in Genetic and Genomic Research, 2012 • Named among the all-time high achievers in Australian health and medical research, by the National Health and Medical Research Council, 2014 • The University of Texas MD Anderson Cancer Center Ernst W. Bertner Memorial Award for Distinguished Contributions to Cancer Research, 2014. • Fellowship of the Australian Academy of Health and Medical Sciences, 2015. • Monash University Faculty of Biomedical and Psychological Sciences Distinguished Alumni Award, 2015. • Named by Thomson Reuters as one of the world’s most influential scientific minds, 2015 • Fellowship of the Royal Society of New South Wales, 2016
PROFESSIONAL HISTORY
1977-1981 Department of Biochemistry, Baylor College of Medicine, Houston, Texas, USA 1977-1979 Research Associate 1979-1981 Member of Faculty (Instructor)
1982-1988 CSIRO Division of Molecular Biology, Sydney 1982-1984 Research Scientist 1984-1987 Senior Research Scientist 1987-1988 Principal Research Scientist
1988-2011 The University of Queensland, Brisbane 1988-2012 Professor of Molecular Biology, Department of Biochemistry 1988-1990 Director, Centre for Molecular Biology and Biotechnology 1991-1993 Director, ARC Special Research Centre for Molecular Biology and Biotechnology 1993-1994 Visiting Scientist, Department of Genetics, University of Cambridge 1994-1999 Director, ARC Special Research Centre for Molecular and Cellular Biology 1996-2002 Director, Australian Genome Research Facility 2000 Visiting Senior Research Fellow, St. John’s College, and Department of Anatomy and Human Genetics, University of Oxford 2000-2002 Co-Director, Institute for Molecular Bioscience 2000-2002 Director, ARC Special Research Centre for Functional and Applied Genomics 2002 Visiting Professor, Institute for Biochemistry, University of Cologne 2003-2005 Director, Institute for Molecular Bioscience 2006-2010 ARC Federation Fellow 2008 Inaugural (visiting) Gutenberg Professor, University of Strasbourg 2010-2013 NHMRC Australia Fellow
John Mattick CV Page 2 2012-present Executive Director, Garvan Institute of Medical Research, Sydney 2012-present Conjoint Professor, St Vincent’s Hospital Clinical School, and Adjunct Professor, School of Biotechnology & Biomolecular Sciences, University of New South Wales 2012-present Honorary Professor, Institute for Molecular Bioscience, The University of Queensland
PROFESSIONAL ACTIVITIES (partial list, see page 65)
• Member, Editorial Boards of Bioessays, Silence, Cell Research, eLife and IUBMB Life • Member, Council of Scientists, Human Frontier Science Program (2005-2008) • Chair, Queensland Studies Authority (2004-2007) • Member, Council, Human Genome Organization (2012-2014) • Member, Council of the Australian Academy of Science (2015-2017)
BIOGRAPHICAL SUMMARY
John Mattick was born in Sydney in 1950. He received his BSc (with First Class Honours) from the University of Sydney in 1972, followed by his PhD in 1978 from Monash University in Melbourne, on the topic of mitochondrial DNA replication and mutation. He undertook postdoctoral work on the molecular biology of the fatty acid synthase complex at Baylor College of Medicine in Houston Texas from 1977 to 1981. He then returned to Australia where he worked at the CSIRO Division of Molecular Biology in Sydney (from 1982 to 1988), and subsequently at the University of Queensland in Brisbane (from 1988 to 2011), where he was the Professor of Molecular Biology, ARC Federation Fellow and later NHMRC Australia Fellow at the Institute for Molecular Bioscience, which he established, along with the Centre for Molecular and Cellular Biology and the Australian Genome Research Facility, among others (see below). He has also spent sabbatical periods at the University of Cambridge (September 1993-March 1994), the University of Oxford (March 2000-September 2000), and the University of Cologne (September 2001-January 2002). In 2012 he was appointed as the Executive Director of the Garvan Institute of Medical Research in Sydney.
Professor Mattick has made several seminal contributions to molecular biology. His postdoctoral work in association with Dr Salih Wakil on the architecture and function of the fatty acid synthase complex is now the standard treatment in all major biochemistry textbooks. He was responsible for the development of one of the first recombinant DNA-based vaccines in the world (against ovine footrot), which was recently credited with eradicating footrot from Nepal. In recognition of this work he was awarded the 1989 Pharmacia-LKB Biotechnology Medal by the Australian Biochemical Society. His laboratory pioneered the genetic analysis of type IV pili, which are surface filaments involved in host attachment and surface translocation by a wide variety of bacterial pathogens, including the cloning and characterization of most of the genes involved. His laboratory was also the first to recognize that these structures are a subset of an evolutionarily and functionally related supersystem involved in the architecture and assembly of surface complexes in bacteria, which have been adapted to protein export, DNA uptake and host colonization. This work was recognized by an invitation to write a major review for Annual Reviews of Microbiology in 2002 on ‘Type IV pili and twitching motility.’
Following his appointment in 1988 as the Foundation Professor of Molecular Biology and Foundation Director of the Centre for Molecular Biology and Biotechnology (CMBBT) at the University of Queensland, Professor Mattick devoted considerable energy to the establishment of this Centre and its maturation into one of the largest research institutes in Australia. The CMBBT focussed on the
John Mattick CV Page 3 molecular genetics of mammals and their diseases, including genome mapping, gene regulation, and developmental and cell biology. It was subsequently designated as a Special Research Centre of the Australian Research Council (ARC), and in 1994 was renamed the ARC Special Research Centre for Molecular and Cellular Biology (CMCB). In 2000 the CMCB amalgamated with the Centre for Drug Design and Development to form the Institute for Molecular Bioscience (IMB), a systems biology institute whose research activities span the spectrum from genomics and computational biology, genetics and developmental biology, molecular cell biology, structural biology and biological chemistry. Professor Mattick was Foundation Co-Director of the IMB from 2000-2002, and Director from 2003-2005, when he relinquished the position to accept an ARC Federation Fellowship to focus on his research into noncoding RNA. At the time of his resignation the IMB had grown to 35 research groups and about 500 staff and research students. During his tenure (1988-2005) as Director of the Centre for Molecular and Cellular Biology, the Australian Genome Research Facility, and the Institute for Molecular Bioscience, Professor Mattick raised over $120m in core funds, not including his own research grants and fellowships or those of others who worked in these centres and institute.
Professor Mattick was also the founder and Foundation Director (1996-2002) of the Australian Genome Research Facility (AGRF), a designated major national research facility which provides large- scale DNA sequencing, genotyping and related services to the Australian and regional research community. He was the Foundation Director of the ARC Special Research Centre for Functional and Applied Genomics (2000-2002), positions he relinquished when he assumed the sole Directorship of the IMB.
Professor Mattick was Chair of the Organizing Committee of the 1999 Human Genome Meeting (HGM’99, Brisbane), and was a member of the Scientific Program Committees of HGM’98 (Turin) and HGM’2000 (Vancouver). He was also Chair of the Interim Review of Genome Canada’s Competition I and II Projects and Platforms, and the Review Panel for the Renewal of Genome Centres, in 2002, 2004 and 2005, respectively. He was a Foundation Member of the Board of the Australian National Genome Information Service (ANGIS), and a Foundation Member and currently Board Member of the Asia-Pacific International Molecular Biology Network (A-IMBN). He has been a Member of the Council of Scientists of the Human Frontier Science Program (HFSP). He has served on project grant and fellowship selection committees for several national and international research funding agencies, including Genome Canada, the Wellcome Trust, the National Health and Medical Research Council, and the Australian Research Council, among others. From 1997-2003 he was a member of the Australian Health Ethics Committee (AHEC) and the Research Committee of the National Health and Medical Research Council, and was involved in the development of the National Statement on the Ethical Conduct of Research involving Humans, the joint Australain Law Reform Commission (ALRC) / AHEC Commonwealth Enquiry into the Protection of Human Genetic Information, the Committee to Revise the Ethical Guidelines on Assisted Reproductive Technology, and the ALCR Reports on Gene Patenting and Genetic Privacy. He was an invited Expert Witness at the 2001 New Zealand Royal Commission on Genetic Engineering, and a participant in the EINSHAC Conferences on Genetics and the Law in 2001 (Hawaii) and 2003 (Sydney). He is also a member of the Advisory Boards of several research institutes in Australia and abroad.
Professor Mattick has also been active in the development of a biotechnology industry in Australia. Apart from the development of a commercial recombinant DNA-based vaccine, he was also involved in the development of Pacific Oligos Pty Ltd (later Proligo Australia), and in the establishment of the IMB commercial arm (IMBcom) which oversaw the establishment of a number of spin-out companies based on IMB research. He speaks frequently to medical conferences, medical societies, science teachers, professional groups, students, and the general public about genome research, biotechnology, and related ethical issues. He was also appointed Chair of the Queensland Studies Authority (2004-2007), the stautaory body that oversees primary and secondary school curriculum development and assessment in that state.
John Mattick CV Page 4 In 2001 Professor Mattick was appointed as an Officer in the Order of Australia (AO) for his services to molecular biology and genomics in Australia. In 2002 he was elected as an Honorary Fellow of the Royal College of Pathologists of Australasia (FRCPA), and in 2003 he was awarded the Centenary Medal by the Australian Government for services to biotechnology. In 2006 he was awarded the CSIRO Eureka Prize for Leadership in Science. In 2007 he was awarded the inaugural Gutenberg Chair at the Université Louis Pasteur de Strasbourg, and elected as an Associate (Foreign) Member of the European Molecular Biology Organisation. In 2008 he was elected a Fellow of the Australian Academy of Science. He was awarded the 2011 International Union of Biochemistry and Molecular Biology (IUBMB) Medal, the 2012 Human Genome Organisation Chen Medal for Distinguished Academic Achievement in Human Genetics and Genomic Research, and the 2014 University of Texas MD Anderson Cancer Center Ernst W. Bertner Memorial Award for Distinguished Contributions to Cancer Research, past recipients of this which include several Nobel laureates and other pioneers of molecular biology.
Professor Mattick’s research interests have been focused for the past two decades on the role of regulatory RNAs in the evolution and development of complex organisms. He has developed the thesis that the majority of the genome of humans and other complex organisms, previously considered to be ‘junk’, is devoted to a vastly expanded regulatory architecture, which is mainly transacted via digital RNA signals and which contains the endogenous program that directs the epigenetic trajectories of differentiation and development. Professor Mattick has published over 280 research articles, which have been cited over 28,000 times (ISI Web of Science), and his work has received editorial coverage in Nature, Science, Scientific American, New Scientist and the New York Times, among others. He is also frequently invited to international meetings to speak on the subject.
PUBLICATIONS
ISI ResearcherID: I-7789-2012 (URL:http://www.researcherid.com/rid/I-7789-2012) Orcid ID: orcid.org/0000-0002-7680-7527
1. Nagley P, Mattick JS, Hall RM and Linnane AW (1975) Biogenesis of mitochondria. 43. A comparative study of petite induction and inhibition of mitochondrial DNA replication in yeast by ethidium bromide and berenil. Molecular and General Genetics 141: 291-304.
2. Hall RM, Mattick JS, Marzuki S and Linnane AW (1975) Evidence for a functional association of DNA synthesis with the membrane in mitochondria of Saccharomyces cerevisiae. Molecular Biology Reports 2: 101-106.
3. Mattick JS and Hall RM (1977) Replicative deoxyribonucleic acid synthesis in isolated mitochondria from Saccharomyces cerevisiae. Journal of Bacteriology 130: 973-982.
4. Mattick JS and Nagley P (1977). Comparative studies of the effects of acridines and other petite inducing drugs on the mitochondrial genome of Saccharomyces cerevisiae. Molecular and General Genetics 152: 267-276.
5. Nagley P and Mattick JS (1977) Mitochondrial DNA replication in petite mutants of yeast: resistance to inhibition by ethidium bromide, berenil and euflavine. Molecular and General Genetics 152: 277-283.
6. Hall RM, Mattick JS, Nagley P, Cobon GS, Eastwood FW and Linnane AW (1977) The action of structural analogues of ethidium bromide on the mitochondrial genome of yeast. Molecular Biology Reports 3: 443-449.
John Mattick CV Page 5 7. Zehner ZE, Mattick JS, Stuart R and Wakil SJ (1980) Goose fatty acid synthetase mRNA. Journal of Biological Chemistry 255: 9519-9522.
8. Mattick JS, Zehner ZE, Calabro MA and Wakil SJ (1981) The isolation and characterization of fatty acid synthetase mRNA from rat mammary gland. European Journal of Biochemistry 114: 643-651.
9. Wakil SJ, Stoops JK and Mattick JS (1981) The fatty acid synthetase: structure-function relationship and mechanism of palmitate synthesis. Cardiovascular Research Centre Bulletin (Houston) 20: 1-23.
10. Gilbert BE and Mattick JS (1981) Homologous mammalian brain cell lysate system for the initiation and translation of exogenous mRNAs. Journal of Neurochemistry 37: 325-332.
11. Kuziora MA, Chalmers JH Jr, Douglas MG, Hitzeman RA, Mattick JS and Wakil SJ (1983) Molecular cloning of fatty acid synthetase genes from Saccharomyces cerevisiae. Journal of Biological Chemistry 258: 11648-11653.
12. Mattick JS, Tsukamoto Y, Nickless J and Wakil SJ (1983) The architecture of the animal fatty acid synthetase. I. Proteolytic dissection and peptide mapping. Journal of Biological Chemistry 258: 15291-15299.
13. Mattick JS, Nickless J, Mizugaki M, Yang C-Y, Uchiyama S and Wakil SJ (1983) The architecture of the animal fatty acid synthetase. II. Separation of the core and thioesterase functions and determination of the N-C orientation of the subunit. Journal of Biological Chemistry 258: 15300- 15304.
14. Wong H, Mattick JS and Wakil SJ (1983) The architecture of the animal fatty acid synthetase. III. Isolation and characterization of b-ketoacyl reductase. Journal of Biological Chemistry 258: 15305-15311.
15. Tsukamoto Y, Wong H, Mattick JS and Wakil SJ (1983) The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action. Journal of Biological Chemistry 258: 15312-15322.
16. Wright IG, Goodger BV, Rode-Bramanis K, Mattick JS, Mahoney DF and Waltisbuhl DJ (1983) The characterization of an esterase derived from Babesia bovis and its use as a vaccine. Zeitschrift fur Parasitenkunde 69: 703-714.
17. Both GW, Mattick JS and Bellamy AR (1983) The serotype-specific glycoprotein of Simian-11 rotavirus: coding assignment and gene sequence. Proceedings of the National Academy of Sciences USA 80: 3091-3095.
18. Both GW, Mattick JS, Siegman L, Atkinson PH, Weiss S, Bellamy AR, Street JE and Metcalf P (1983) Cloning of SA11 rotavirus genes: gene structure and polypeptide assignment for the type-specific glycoprotein. In: Double-stranded RNA Viruses (Compans RW and Bishop DHL, eds.), Academic Press, New York, pp. 73-82.
19. Mattick JS, Anderson BJ, Mott MR and Egerton JR (1984) The isolation and characterization of the fimbriae of Bacteroides nodosus: structural subunit and basal protein antigens. Journal of Bacteriology 160: 740-747.
20. Anderson BJ, Bills MM, Egerton JR and Mattick JS (1984) Cloning and expression in Escherichia coli of the gene encoding the structural subunit of the fimbriae of Bacteroides nodosus. Journal of Bacteriology 160: 748-754.
John Mattick CV Page 6 21. Groot Obbink DJ, Ritchie LJ, Cameron FH, Mattick JS and Ackerman VP (1985) Construction of a gentamicin resistance gene probe for epidemiological studies. Antimicrobial Agents and Chemotherapy 28: 96-102.
22. Mattick JS, Anderson BJ and Egerton JR (1985) Molecular biology and footrot. Reviews in Rural Science 6: 79-90.
23. Mattick JS, Anderson BJ, Mott MR and Egerton JR (1986) Isolation and characterization of Bacteroides nodosus fimbriae: structural subunit and basal protein antigens. In: Footrot in Ruminants: Proceedings of a Workshop, Melbourne (Stewart DJ, Petersen JE, McKern NM, Emery DL, eds.) CSIRO Australia, pp. 211-217.
24. Anderson BJ, Egerton JR and Mattick JS (1986) Electrophoretic and antigenic variation in the structural subunit and basal protein of Bacteroides nodosus fimbriae. In: Footrot in Ruminants: Proceedings of a Workshop, Melbourne (Stewart DJ, Petersen JE, McKern NM, Emery DL, eds.) CSIRO Australia, pp. 219-226.
25. Mattick JS, Anderson BJ, Bills MM and Egerton JR (1986) The cloning and expression of the genes encoding the fimbriae of Bacteroides nodosus. In: Footrot in Ruminants: Proceedings of a Workshop, Melbourne (Stewart DJ, Petersen JE, McKern NM, Emery DL, eds.) CSIRO Australia, pp. 249-256.
26. Moses EK, Yong WK, Mattick JS and Rifkin CG (1986) Expression of Bacteroides nodosus genes encoding extracellular proteins in Escherichia coli. In: Footrot in Ruminants: Proceedings of a Workshop, Melbourne (Stewart DJ, Petersen JE, McKern NM, Emery DL, eds.) CSIRO Australia, pp. 245-247.
27. Anderson BJ, Kristo CL, Egerton JR and Mattick JS (1986) Variation in the structural subunit and basal protein antigens of Bacteroides nodosus fimbriae. Journal of Bacteriology 166: 453- 460.
28. Dalrymple B and Mattick JS (1986) Genes encoding threonine tRNAs with the anticodon CGU from Escherichia coli and Pseudomonas aeruginosa. Biochemistry International 13: 547-553.
29. Mattick JS, Anderson BJ, Bills MM, Cox PT, Dalrymple B, Egerton JR, Elleman TC, Finney K, Hoyne PA, Lehrbach P, McKern NM, McNicholas P, Schwartzkoff CL, Stewart DJ and Wright D (1986) Anaerobe to aerobe: the development of a recombinant DNA-based vaccine against ovine footrot. In: Proceedings of the Seventh Australian Biotechnology Conference, Melbourne, pp. 91-96.
30. Mattick JS, Bills MM, Anderson BJ, Dalrymple BP, Mott MR and Egerton JR (1987) Morphogenetic expression of Bacteroides nodosus fimbriae in Pseudomonas aeruginosa. Journal of Bacteriology 169: 33-41.
31. Dalrymple B and Mattick JS (1987) An analysis of the structure and evolution of type 4 fimbrial proteins. Journal of Molecular Evolution 25: 261-269.
32. Anderson BJ, Mattick JS, Cox PT, Kristo CL and Egerton JR (1987) Western blot (immunoblot) analysis of the fimbrial antigens of Bacteroides nodosus. Journal of Bacteriology 169: 4018-4023.
33. Egerton JR, Cox PT, Anderson BJ, Kristo CL, Norman M and Mattick JS (1987) Protection of sheep against footrot with a recombinant DNA-based fimbrial vaccine. Veterinary Microbiology 14: 393-409.
John Mattick CV Page 7 34. Scott NA, Whalley JM, Mattick JS, Underwood PA, Aboud L, Williams KL and Kirkland P (1988) Identification of major antigenic proteins of bovine herpes virus 1 and their correlation with virus neutralizing activity. Veterinary Microbiology 16: 109-121.
35. Hobbs M, Dalrymple BP, Delaney S and Mattick JS (1988) Transcription of the fimbrial subunit gene and an associated transfer RNA gene from Pseudomonas aeruginosa. Gene 62: 219-227.
36. Jennings PA, Bills MM, Irving DA and Mattick JS (1989) Fimbriae of Bacteroides nodosus: protein engineering of the structural subunit for the production of exogenous peptides. Protein Engineering 2: 365-369.
37. Mattick JS (1989) The molecular biology of the fimbriae (pili) of Bacteroides nodosus and the development of a recombinant DNA-based vaccine. In Footrot and Foot Abscess of Ruminants (Egerton JR, Yong, WK, Rifkin GG, eds.) CRC Press, Boca Raton, pp. 196-218.
38. Mattick JS (1989) Of mice and men - exploring the genetic database. Todays Life Science 1: 6- 12.
39. Mattick JS (1990) Genome research (letter). Nature 346: 604.
40. Gottesman S, Squires C, Pichersky E, Carrington M, Hobbs M, Mattick JS, Dalrymple BP, Kuramitsu H, Shiroza T, Foster T, Clark WP, Ross B, Squires CL and Maurizi MR (1990) Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes. Proceedings of the National Academy of Sciences USA 87: 3513-3517.
41. Beard MK, Mattick JS, Moore LJ, Mott MR, Marrs CF and Egerton JR (1990) Morphogenetic expression of Moraxella bovis fimbriae (pili) in Pseudomonas aeruginosa. Journal of Bacteriology 172: 2601-2607.
42. Mattick JS and Hobbs M (1990) The development of a genetically engineered vaccine against ovine footrot. Todays Life Science 2: 34-42.
43. Smith GA, Young PL and Mattick JS (1990) The location and nucleotide sequence of the thymidine kinase gene of bovine herpesvirus type 1.2. Journal of General Virology 71: 2417-2424.
44. Smith GA, Young PL and Mattick JS (1991) Nucleotide and amino acid sequence analysis of the thymidine kinase gene of a bovine encephalitis herpesvirus. Archives of Virology 119: 199-210.
45. Mattick JS, Anderson BJ, Cox PT, Dalrymple BP, Bills MM, Hobbs M and Egerton JR (1991) Gene sequences and comparison of the fimbrial subunits representative of Bacteroides nodosus serotypes A to I: class I and class II strains. Molecular Microbiology 5: 561-573.
46. Hobbs M, Dalrymple BP, Cox PT, Livingston SP, Delaney SF and Mattick JS (1991) Organization of the fimbrial gene region of Bacteroides nodosus: class I and class II strains. Molecular Microbiology 5: 543-560.
47. Whitchurch CB, Hobbs M, Livingston SP, Krishnapillai V and Mattick JS (1991) Characterization of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria. Gene 101: 33-44.
48. Moore SS, Sargeant LL, King TJ, Mattick JS, Georges M and Hetzel DJS (1991) The conservation of dinucleotide microsatellites among mammalian genomes allows the use of heterologous PCR primer pairs in closely related species. Genomics 10: 654-660.
49. Don RH, Cox PT, Wainwright BJ, Baker K and Mattick JS (1991) ‘Touchdown’ PCR to circumvent spurious priming during gene amplification. Nucleic Acids Research 19: 4008.
John Mattick CV Page 8 50. Cox PT, Don RH and Mattick JS (1991) Rapid animal disease diagnosis: the future is PCR. Lab Animal 20: 22-30.
51. Patel P, Marrs CF, Mattick JS, Ruehl WW, Taylor RK and Koomey M (1991) Shared antigenicity and immunogenicity of type 4 pilins expressed by Pseudomonas aeruginosa, Moraxella bovis, Neisseria gonorrhoeae, Dichelobacter nodosus, and Vibrio cholerae. Infection and Immunity 59: 4674-4676.
52. Diefenbach RJ, Candy JM, Mattick JS and Duggleby RG (1992) Effects of substitution of aspartate-440 and tryptophan-487 in the thiamin diphosphate binding region of pyruvate decarboxylase from Zymomonas mobilis. FEBS Letters 296: 95-98.
53. Candy JM, Duggleby RG and Mattick JS (1992) Expression of active yeast pyruvate decarboxylase in Escherichia coli. Journal of General Microbiology 137: 2811-2815.
54. Abedinia M, Layfield R, Jones SM, Nixon PF and Mattick JS (1992) Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase. Biochemical and Biophysical Research Communications 183: 1159-1166.
55. Mattick JS, Ablett EM and Edmondson DL (1992) The Gene Library - preservation and analysis of genetic diversity in Australia. In Conservation of Plant Genes through DNA Banking and in vitro Biotechnology (Adams RP, ed.), Academic Press, New York, pp. 15-35.
56. Mattick JS, Hobbs M, Cox PT and Dalrymple BP (1992) Molecular biology of the fimbriae of Dichelobacter (prev. Bacteroides) nodosus. In Genetics and Molecular Biology of Anaerobic Bacteria (Sebald M, ed.), Springer-Verlag, New York, pp. 517-545.
57. Lapsys NM, Layfield R, Baker E, Callen DF, Sutherland GR, Abedinia M, Nixon PF and Mattick JS (1992) Chromosomal location of the transketolase gene. Cytogenetics and Cell Genetics 6: 274-275.
58. Candy JM, Diefenbach RJ, Mattick JS and Duggleby RG (1992) Revised sequence for the Zymomonas mobilis pyruvate decarboxylase gene and protein. Biochemistry (Life Science Advances) 11: 59-63.
59. Gobius KS, Barnard R, Rowlinson SR, Mattick JS and Waters MJ (1992) The first disulphide loop of the rabbit growth hormone receptor is required for binding to the hormone. Journal of Molecular Endocrinology 9: 213-220.
60. Don RH, Cox PT and Mattick JS (1993) A one tube reaction for synthesis and amplification of total cDNA from small numbers of cells. Nucleic Acids Research 21:783.
61. Ruehl WW, Marrs CF, Beard MK, Shokooki V, Hinojoza JR, Banks S, Bieber D and Mattick JS (1993) Q pili enhance the attachment of Moraxella bovis to bovine corneas in vitro. Molecular Microbiology 7: 285-288.
62. Hobbs M, Collie ESR, Free PD, Livingston SP and Mattick JS (1993) PilS and PilR, a two- component transcriptional regulatory system controlling expression of type 4 fimbriae in Pseudomonas aeruginosa. Molecular Microbiology 7: 669-682.
63. Smith GA, Young PL and Mattick JS (1993) Bovine herpesvirus 1.1 - an exotic disease agent? Australian Veterinary Journal 70: 272-273.
64. Martin PR, Hobbs M, Free PD, Jeske Y and Mattick JS (1993) Characterization of pilQ, a new gene required for the biogenesis of type 4 fimbriae in Pseudomonas aeruginosa. Molecular Microbiology 9: 857-868.
John Mattick CV Page 9 65. Hobbs M and Mattick JS (1993) Common components in the assembly of type 4 fimbriae, DNA transfer systems, filamentous phage and protein secretion apparatus: a general system for the formation of surface-associated protein complexes. Molecular Microbiology 10: 233-243.
66. Smith GA, Young PL, Rodwell BJ, Kelly MA, Storie GJ, Farrah CA and Mattick JS (1994) Development and trial of a bovine herpesvirus 1 - thymidine kinase deletion virus as a vaccine. Australian Veterinary Journal 71:65-70.
67. Spring KJ, Mattick JS and Don RH (1994) Escherichia coli gpt as a positive and negative selectable marker in embryonal stem cells. Biochimica Biophysica Acta 1218: 158-162.
68. Tennent JM and Mattick JS (1994) Type 4 fimbriae. In Fimbriae: aspects of adhesion, genetics, biogenesis and vaccines (Klemm P, ed.), CRC Press, Boca Raton, pp. 127-146.
69. Alm RA, Dalrymple BP and Mattick JS (1994) Sequencing and expression of the aroA gene from Dichelobacter nodosus. Gene 145: 97-101.
70. Ablett EM and Mattick JS (1994) Conservation of invertebrate biodiversity: the role of ex-situ preservation of genetic material. Memoirs of the Queensland Museum 36: 3-6.
71. Whitchurch CB and Mattick JS (1994) Characterisation of a gene pilU required for twitching motility but not phage sensitivity in Pseudomonas aeruginosa. Molecular Microbiology 13: 1079- 1091.
72. Whitchurch CB and Mattick JS (1994) Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake, and the assembly of type 4 fimbriae in other bacteria. Gene 150: 9-15.
73. Mattick JS (1994) Introns - evolution and function. Current Opinion in Genetics and Development 4: 823-831.
74. Alm RA and Mattick JS (1995) Identification of a gene, pilV, required for type 4 fimbrial biogenesis in Pseudomonas aeruginosa whose product possesses a prepilin-type leader sequence and displays homology to members of the protein secretion networks. Molecular Microbiology 16: 485-496.
75. Martin PR, Watson AA, McCaul TF and Mattick JS (1995) Characterization of a five gene cluster required for the biogenesis of type 4 fimbriae in Pseudomonas aeruginosa. Molecular Microbiology 16: 497-508.
76. Mattick JS and Alm RA (1995) Common architecture of type 4 fimbriae and complexes involved in macromolecular traffic. Trends in Microbiology 3: 411-413.
77. Alm RA, Bodero AJ, Watson AA and Mattick JS (1996) Identification of a novel gene, pilZ, essential for type 4 fimbrial biogenesis in Pseudomonas aeruginosa. Journal of Bacteriology 178: 46-53.
78. Kennedy HD, Ramsdale T, Mattick JS and Little MH (1996) An RNA recognition motif in WT1 revealed by structural modelling. Nature Genetics 12: 329-332.
79. Watson AA, Alm RA and Mattick JS (1996) Construction of improved vectors for protein production in Pseudomonas aeruginosa. Gene 172: 163-164.
80. Mattick JS (1996) A genome project of our own. Todays Life Science 8: 23-26.
81. Watson AA, Mattick JS and Alm RA (1996) Functional expression of heterologous type 4 fimbriae in Pseudomonas aeruginosa. Gene 175: 143-150.
John Mattick CV Page 10 82. Alm RA and Mattick JS (1996) Identification of two genes with prepilin-like leader sequences involved in type 4 fimbrial biogenesis in Pseudomonas aeruginosa. Journal of Bacteriology 178: 3809-3817.
83. Whitchurch CB, Alm RA and Mattick JS (1996) The alginate regulator AlgR and an associated sensor FimS are required for twitching motility in Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences USA 93: 9839-9843.
84. Mattick JS, Whitchurch CB and Alm RA (1996) The molecular genetics of type 4 fimbriae in Pseudomonas aeruginosa - a review. Gene 179: 147 -155.
85. Watson AA, Alm RA and Mattick JS (1996) Identification of a gene, pilF, required for type 4 fimbrial biogenesis and twitching motility in Pseudomonas aeruginosa. Gene 180: 49-56.
86. Alm RA, Hallinan JP, Watson AA and Mattick JS (1996) Fimbrial biogenesis genes of Pseudomonas aeruginosa: pilW and pilX increase the similarity of type 4 fimbriae to the GSP protein secretion systems and pilY1 encodes a gonococcal PilC homolog. Molecular Microbiology 22: 161-173.
87. Alm AA and Mattick JS (1997) Genes involved in the biogenesis and function of type-4 fimbriae in Pseudomonas aeruginosa. Gene 192: 89-98.
88. Wood SA, Pascoe WS, Ru K, Yamada T, Hirchenhain J, Kemler R and Mattick JS (1997) Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene. Mechanisms of Development 63: 29-38.
89. Kennedy HD, Wood SA, Ramsdale T, Tam PPL, Steiner KA and Mattick JS (1997) Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif. Biomedical Peptides, Proteins and Nucleic Acids 2: 93-99.
90. Taya S, Yamamoto T, Kano K, Kawano Y, Iwamatsu A, Tsuchiya T, Tanaka K, Kanai M, Wood SA, Mattick JS and Kaibuchi K (1998) The Ras target AF-6 is a physiological substrate of the Fam ubiquitinating enzyme. Journal of Cell Biology 142: 1053-1062.
91. Mattick JS (1999) Let’s show what we’re made of. Opinion. The Australian, p. 13, January 4, 1999.
92. Bolton J, Wood S, Kennedy D, Don RH and Mattick JS (1999) Retinoic acid-dependent upregulation of mouse folate receptor alpha expression in embryonic stem cells, and conservation of alternative splicing patterns. Gene 230: 215-224.
93. McCarthy FM, Smith GA and Mattick JS (1999) Molecular characterisation of Australian bovine enteroviruses. Veterinary Microbiology 68: 71-81.
94. Comolli JC, Hauser AR, Waite L, Whitchurch CB, Mattick JS and Engel JN (1999) Pseudomonas aeruginosa gene products PilT and PilU are required for cytotoxicity in vitro and virulence in a mouse model of acute pneumonia. Infection and Immunity 67: 3625-3630.
95. Semmler ABT, Whitchurch CB and Mattick JS (1999) A re-examination of twitching motility in Pseudomonas aeruginosa. Microbiology 145: 2863-2873.
96. Kanai-Azuma M, Mattick JS, Kaibuchi K and Wood SA (2000) Co-localization of FAM and AF-6, the mammalian homologues of Drosophila faf and canoe, in mouse eye development. Mechanisms of Development 91: 383-386.
John Mattick CV Page 11 97. Guliani S, Smith GA, Young PL, Mattick JS and Mahony TJ (1999) Reactivation of a macropod herpesvirus from the eastern grey kangaroo (Macropus giganteus) following corticosteroid treatment. Veterinary Microbiology 68: 59-69.
98. Semmler ABT, Whitchurch CB, Leech AJ and Mattick JS (2000) Identification of a novel gene, fimV, involved in twitching motility in Pseudomonas aeruginosa. Microbiology 146: 1321-1332.
99. Croft L, Schandorff S, Clark F, Burrage K, Arctander P and Mattick JS (2000) ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome. Nature Genetics 24: 340-341.
100. Croft LJ, Beatson SA, Whitchurch CB, Huang B, Blakeley RL and Mattick JS (2000) An interactive web-based Pseudomonas aeruginosa genome database: discovery of new genes, pathways and structures. Microbiology 146: 2351-2364.
101. Fitzgerald J, Kennedy D, Viseshakul N, Cohen BN, Mattick JS, Bateman JF and Forsayeth JR (2000) UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA- binding protein. Brain Research 877: 110-123.
102. Huang B, Whitchurch CB, Croft LJ, Beatson SA and Mattick JS (2000) A minimal tiling path cosmid library for functional analysis of the Pseudomonas aeruginosa PAO1 genome. Microbial and Comparative Genomics 5: 189-203.
103. Mattick JS (2000) Genomics down under. EMBO Reports 1: 204-207.
104. Ross BC, Czajkowski L, Hocking D, Margetts M, Webb E, Rothel L, Patterson M, Agius C, Camuglia S, Reynolds E, Littlejohn T, Gaeta B, Ng A, Kuczek ES, Mattick JS, Gearing D and Barr IG (2001) Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis. Vaccine 19: 4135-4142.
105. Mattick JS and Gagen MJ (2001) The evolution of controlled multitasked gene networks: the role of introns and other noncoding RNAs in the development of complex organisms. Molecular Biology and Evolution 18: 1611-1630.
106. Pantaleon M, Kanai-Azuma M, Mattick JS, Kaibuchi K, Kaye PL and Wood SA (2001) FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mechanisms of Development 109: 151-160.
107. Mattick JS (2001) Noncoding RNAs: the architects of eukaryotic complexity. EMBO Reports 2: 986-991.
108. Kennedy D, French J, Guitard E, Ru K, Tocque B and Mattick JS (2002) Characterisation of G3BPs: tissue specific expression, chromosomal localisation and rasGAP120 binding studies. Journal of Cell Biochemistry 84: 173-187.
109. Utama B, Kennedy D, Ru K and Mattick JS (2002) Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. Genes to Cells 7: 115-132.
110. Whitchurch CB, Tolker-Nielsen T, Ragas PC and Mattick JS (2002) Extracellular DNA required for bacterial biofilm formation. Science 295: 1487.
111. Beatson SA, Whitchurch CB, Semmler ABT and Mattick JS (2002) Quorum sensing is not required for twitching motility in Pseudomonas aeruginosa. Journal of Bacteriology 184: 3598-3604.
John Mattick CV Page 12 112. Beatson SA, Whitchurch CB, Sargent JL, Levesque RC and Mattick JS (2002) Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa. Journal of Bacteriology 184: 3605-3613.
113. Whitchurch CB, Erova T, Emery JA, Sargent JL, Harris JM, Semmler ABT, Young MD, Mattick JS and Wozniak DJ (2002) Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbria-mediated twitching motility. Journal of Bacteriology 184: 4544-4554.
114. Guliani S, Polkinghorne I, Smith GA, Young P, Mattick JS and Mahony TJ (2002) Macropodid herpesvirus 1 encodes genes for both thymidylate synthase and ICP34.5. Virus Genes 24: 207-213.
115. Yuan Z, Burrage K and Mattick JS (2002) Prediction of protein solvent accessibility using support vector machines. Proteins 48: 566-570.
116. Mattick JS (2002) Type IV pili and twitching motility. Annual Review of Microbiology 56: 289- 314.
117. Nouwens AS, Beatson SA, Whitchurch CB, Walsh BJ, Schweizer HP, Mattick JS and Cordwell SJ (2003) Proteome analysis of extracellular proteins regulated by the las and rhl quorum sensing systems in Pseudomonas aeruginosa. Microbiology 149: 1311-1322.
118. Tajul-Arifin K, Teasdale R, Ravasi T, Hume DA, RIKEN GER Group and GSL Members, and Mattick JS (2003) Identification and analysis of chromodomain-containing proteins encoded in the mouse transcriptome. Genome Research 13: 1416–1429.
119. Saunders NFW, Thomas T, Curmi PMG, Mattick JS, Kuczek E, Slade R, Davis J, Franzmann PD, Boone D, Rusterholtz K, Feldman R, Gates C, Bench S, Sowers K, Kadner K, Aerts A, Dehal P, Detter C, Glavina T, Lucas S, Richardson P, Larimer F, Hauser L, Land M and Cavicchioli R (2003) Mechanisms of thermal adaptation revealed from the genomes of the Antarctic archaea Methanogenium frigidum and Methanococcoides burtonii. Genome Research 13: 1580-1588.
120. Mattick JS (2003) The human genome and the future of medicine. Medical Journal of Australia 179: 212-216.
121. Mattick JS (2003) Challenging the dogma: the hidden layer of non-protein-coding RNAs in complex organisms. Bioessays 25: 930-939.
122. Mattick JS (2003) Noncoding RNAs: a regulatory role? In Nature Encyclopaedia of the Human Genome (Cooper DN, ed.), Nature Publishing Group, Macmillan Publishers Ltd.
123. Mattick JS (2003) Introns and noncoding RNAs: the hidden layer of eukaryotic complexity. In Noncoding RNAs: Molecular Biology and Molecular Medicine (Barciszewski J, Erdmann VA, eds.), pp. 11-32, Landes Bioscience, Georgetown TX.
124. Huang B, Whitchurch CB and Mattick JS (2003) FimX, a multi-domain protein connecting environmental signals to twitching motility in Pseudomonas aeruginosa. Journal of Bacteriology 185: 7068-7076.
125. Taft RJ and Mattick JS (2003) Increasing biological complexity is positively correlated with the relative genome-wide expansion of non-protein-coding DNA sequences. Genome Biology 5: 1-24 (http://genomebiology.com/2003/5/1/P1).
John Mattick CV Page 13 126. Croft LJ, Lercher MJ, Gagen MJ and Mattick JS (2003) Is prokaryotic complexity limited by regulatory overhead? http://genomebiology.com/qc/2003/5/1/p2 and http://arXiv.org/abs/q- bio.MN/0311021.
127. Gagen MJ and Mattick JS (2004) Inherent size constraints on prokaryote gene networks due to “accelerating” growth. http://arXiv.org/abs/q-bio.MN/0312021.
128. Gagen MJ and Mattick JS (2004) Failed “nonaccelerating” models of prokaryote gene regulatory networks. http://arXiv.org/abs/q-bio.MN/0312022.
129. Mattick JS (2004) RNA regulation: a new genetics? Nature Reviews Genetics 5: 316-323.
130. Mattick JS (2004) Response to A. M. Poole: Is all that junk really regulatory RNA? Nature Reviews Genetics 5: doi:10.1038/nrg1321-c2.
131. Whitchurch CB, Leech AJ, Young MD, Kennedy HD, Sargent JL, Bertrand JJ, Semmler ABT, Mellick AS, Martin PR, Alm RA, Hobbs M, Beatson SA, Huang B, Nguyen L, Comolli JC, Engel JN, Darzins A and Mattick JS (2004) Characterization of a complex signal transduction system which controls twitching motility in Pseudomonas aeruginosa. Molecular Microbiology 52: 873-893.
132. Huang B, Ru K, Yuan Z, Whitchurch CB and Mattick JS (2004) tonB3 is required for normal twitching motility and extracellular assembly of type IV pili. Journal of Bacteriology 186: 4387-4389.
133. Yuan Z, Mattick JS and Teasdale RD (2004) SVMtm: support vector machines to predict transmembrane segments. Journal of Computational Chemistry 25: 632-636.
134. Bejerano G, Pheasant M, Makunin IV, Stephen S, Kent WJ, Mattick JS and Haussler D (2004) Ultra-conserved elements in the human genome. Science 304: 1321-1325.
135. Mattick JS (2004) The hidden genetic program of complex organisms. Scientific American 291(4): 60-67.
136. Mattick JS (2004) Digital RNA regulation of complex organisms. Gene Therapy and Regulation 2: 313-319.
137. Pang KC, Stephen S, Engström PG, Tajul-Arifin K, Chen W, Wahlestedt C, Lenhard B, Hayashizaki Y and Mattick JS (2005) RNAdb – a comprehensive mammalian noncoding RNA database. Nucleic Acids Research 33: D125-D130.
138. Whitchurch CB, Beatson SA, Comolli JC, Jakobsen T, Sargent JL, Bertrand JJ, West J, Klausen M, Waite LL, Kang PJ, Tolker-Nielsen T, Mattick JS and Engel JN (2005) Pseudomonas aeruginosa fimL regulates multiple virulence functions by intersecting with Vfr-modulated pathways. Molecular Microbiology 55: 1357-1378.
139. Gagen MJ and Mattick JS (2005) Inherent size constraints on prokaryote gene networks due to “accelerating” growth. Theory in Biosciences 123: 381-411.
140. Mattick JS and Makunin IV (2005) Small regulatory RNAs in mammals. Human Molecular Genetics 14: R121-R132.
141. Mattick JS and Gagen MJ (2005) Accelerating networks. Science 307: 856-858.
142. Frith MC, Pheasant M and Mattick JS (2005) The amazing complexity of the human transcriptome. European Journal of Human Genetics 13: 894-897.
John Mattick CV Page 14 143. Mattick JS (2005) What makes a human? The Scientist 19(4): 32-33.
144. Glazov EA, Pheasant M, McGraw EA, Bejerano G and Mattick JS (2005) Ultraconserved elements in insect genomes: a highly conserved intronic sequence implicated in the control of homothorax mRNA splicing. Genome Research 15: 800-808.
145. Gagen MJ and Mattick JS (2005) Accelerating, hyper-accelerating and decelerating networks. Physical Review E 72: 016123.
146. Mattick JS (2005) The functional genomics of noncoding RNA. Science 309: 1527-1528.
147. Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest ARR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen J, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engström PG, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Harokopos V, Hayashi Y, Henning S, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SPT, Kruger AF, Kummerfeld SK, Kurochkin IV, Lareau LF, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Qu W, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg S, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CAM, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J and Hayashizaki Y (2005) The transcriptional landscape of the mammalian genome. Science 309: 1559-1563.
148. Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith MC, Ravasi T, Pang KC, Mattick JS, Hume DA, Lipovich L, Engström PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk A, Mottagui-Tabar S, Liang Z, Lenhard B and Wahlested C (2005) Antisense transcription in the mammalian transcriptome. Science 309: 1564-1566.
149. Ravasi T, Suzuki H, Pang KC, Katayama S, Furuno M, Okunishi R, Fukuda S, Ru K, Frith M, Gongora M, Grimmond S, Hume DA, Hayashizaki Y and Mattick JS (2006) Experimental validation of the regulated expression of large numbers of noncoding RNAs from the mouse genome. Genome Research 16: 11-19.
150. Pang KC, Frith MC and Mattick JS (2006) Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function. Trends in Genetics 22: 1-5.
151. Simons C, Pheasant M, Makunin IV and Mattick JS (2006) Transposon-free regions in mammalian genomes. Genome Research 16: 164-172.
John Mattick CV Page 15 152. Stanley S, Bailey TC and Mattick JS (2006) GONOME: measuring correlations between GO terms and genomic positions. BMC Bioinformatics 7: 94.
153. Hallinan JS, Bradley DR, Mattick JS and Wiles JH (2006). Effects of an RNA control layer on the state space of boolean models of genetic regulatory networks. 2006 IEEE Congress on Evolutionary Computation, Vancouver, Canada, (2551-2555).
154. Mattick JS (2006) Book review: the underworld of RNA. Nature Genetics 38: 393.
155. Furuno M, Pang KC, Ninomiya N, Fukuda S, Frith MC, Bult C, Mattick JS and Suzuki H (2006) Clusters of internally primed transcripts reveal novel long noncoding RNAs. PLoS Genetics 2: 537-553.
156. Mattick JS and Makunin IV (2006) Non-coding RNA. Human Molecular Genetics 15: R17-R29.
157. Glazov EA, Pheasant M, Nahkuri S and Mattick JS (2006) Evidence for control of splicing by alternative RNA secondary structures in Dipteran homothorax pre-mRNA. RNA Biology 3: 36- 39.
158. Frith MC, Bailey TL, Kasukawa T, Mignone F, Kummerfeld SK, Madera M, Sunkara S, Furuno M, Bult CJ, Quackenbush J, Kai C, Kawai J, Carninci P, Hayashizaki Y, Pesole G and Mattick JS (2006) Discrimination of non-protein-coding transcripts from protein-coding mRNA. RNA Biology 3: 40-48.
159. Kenzelmann M, Rippe K and Mattick JS (2006) RNA: Networks & Imaging. Molecular Systems Biology 2: 1-7.
160. Mehler MF and Mattick JS (2006) Non-coding RNAs in the nervous system. Journal of Physiology 575: 333-341.
161. Leech AJ and Mattick JS (2006) The effect of site-specific mutations in different phosphotransfer domains of the chemosensory protein ChpA on Pseudomonas aeruginosa motility. Journal of Bacteriology 188: 8479–8486.
162. Pang KC, Stephen S, Dinger ME, Engström PG, Lenhard B and Mattick JS (2007) RNAdb 2.0 – an expanded database of mammalian noncoding RNAs. Nucleic Acids Research 35: D178- D182.
163. Taft RJ, Pheasant M and Mattick JS (2007) The relationship between non-protein-coding DNA and eukaryotic complexity. Bioessays 29: 288-299.
164. Mattick JS (2007) A new paradigm for developmental biology. Journal of Experimental Biology 210: 1526-1547.
165. Mattick JS (2007) Noncoding RNA and RNA regulatory networks in the systems biology of animals. In Systems Biology Volume I: Genomics (Rigoutsos I, Stephanopolous G, eds), pp. 269-301, Oxford University Press, Oxford.
166. Mehler MF and Mattick JS (2007) Non-coding RNAs and RNA editing in brain development, functional diversification and neurological disease. Physiological Reviews 87: 799-823.
167. Pheasant M and Mattick JS (2007) Raising the estimate of functional human sequences. Genome Research 17: 1245-1253.
168. Birney, et al. The ENCODE Project Consortium (incl. Mattick JS) (2007) Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447: 799-816.
John Mattick CV Page 16 169. Simons C, Makunin IV, Pheasant M and Mattick JS (2007) Maintenance of transposon-free regions throughout vertebrate evolution. BMC Genomics 8:470.
170. Amaral PP, Dinger ME, Mercer TR and Mattick JS (2008) The eukaryotic genome as an RNA machine. Science 319: 1787-1789.
171. Dinger ME, Amaral PP, Mercer TR, Pang KC, Bruce SJ, Gardiner BB, Askarian-Amiri ME, Ru K, Soldà G, Simons C, Sunkin SM, Crowe ML, Grimmond SM, Perkins AC and Mattick JS (2008) Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Research 18: 1433–1445.
172. Dinger ME, Pang KC, Mercer TR and Mattick JS (2008) Differentiating protein-coding and noncoding RNA: challenges and ambiguities. PLoS Computational Biology 4: e1000176.
173. Dinger ME, Mercer TR and Mattick JS (2008) RNAs as extracellular signaling molecules. Journal of Molecular Endocrinology 40: 151-159.
174. Keith JM, Adams P, Stephen S and Mattick JS (2008) Delineating slowly and rapidly evolving fractions of the Drosophila genome. Journal of Computational Biology 15: 407-430.
175. Korbie DJ and Mattick JS (2008) Touchdown PCR for increased specificity and sensitivity in PCR amplification. Nature Protocols 3: 1452-1456.
176. Mattick JS (2008) A new understanding of the human genome. Lab&More 2: 8-9 [German version: Ein neues Verständnis des humanen Genoms. Lab&More 5: 6-8.]
177. Mattick JS and Mehler MF (2008) RNA editing, DNA recoding and the evolution of human cognition. Trends in Neuroscience 31: 227-233.
178. Mattick JS, Amaral PP, Dinger ME, Mercer TR and Mehler MF (2008) RNA control of epigenetic processes. Australian Biochemist 39 (2): 4-8.
179. Mercer TR, Dinger ME, Mariani J, Kosik KS, Mehler MF and Mattick JS (2008) Non-coding RNAs in long-term memory formation. The Neuroscientist 14: 434-445.
180. Mercer TR, Dinger ME, Sunkin SM, Mehler MF and Mattick JS (2008) Specific expression of non-coding RNAs in mouse brain. Proceedings of the National Academy of Sciences USA 105: 716-721.
181. Nahkuri S, Taft RJ, Korbie DJ and Mattick JS (2008) Molecular evolution of the HBII-52 snoRNA cluster. Journal of Molecular Biology 381: 810-815.
182. Stephen S, Pheasant M, Makunin IV and Mattick JS (2008) Large-scale appearance of ultraconserved elements in tetrapod genomes and slowdown of the molecular clock. Molecular Biology and Evolution 25: 402-408.
183. Amaral PP and Mattick JS (2008) Noncoding RNA in development. Mammalian Genome 19: 454-492.
184. Amaral PP, Neyt C, Wilkins SJ, Askarian-Amiri ME, Sunkin SM, Perkins AC and Mattick JS (2009) Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA 15: 2013–2027.
185. Dinger ME, Amaral PP, Mercer TR and Mattick JS (2009) Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications. Briefings in Functional Genomics and Proteomics 8: 407-423.
John Mattick CV Page 17 186. Dinger ME, Pang KC, Mercer TR, Crowe ML, Grimmond SM and Mattick JS (2009) NRED: a database of long noncoding RNA expression. Nucleic Acids Research 37: D122-D126.
187. Guffanti A, Iacono M, Pelucchi P, Kim N, Soldà G, Croft LJ, Taft RJ, Rizzi E, Askarian-Amiri M, Bonnal RJ, Callari M, Mignone F, Pesole G, Bertalot G, Bernardi LR, Albertini A, Lee C, Mattick JS, Zucchi I and de Bellis G (2009) A transcriptional sketch of a primary human breast cancer by 454 deep sequencing. BMC Genomics 10:163.
188. Mattick JS (2009) Deconstructing the dogma: a new view of the evolution and genetic programming of complex organisms. Annals of the New York Academy of Sciences 1178: 29- 46.
189. Mattick JS (2009) Has evolution learnt how to learn? EMBO Reports 10: 665.
190. Mattick JS (2009) The genetic signatures of noncoding RNAs. PLoS Genetics 5: e1000459.
191. Mattick JS, Amaral PP, Dinger ME, Mercer TR and Mehler MF (2009) RNA regulation of epigenetic processes. Bioessays 31: 51-59.
192. Mercer TR, Dinger ME and Mattick JS (2009) Long noncoding RNAs: insights into functions. Nature Reviews Genetics 10: 155-159.
193. Nahkuri S, Taft RJ and Mattick JS (2009) Nucleosomes are preferentially positioned at exons in somatic and sperm cells. Cell Cycle 8: 3420-3424.
194. Pang KC, Dinger ME, Mercer TR, Malquori LL, Grimmond SM, Chen W and Mattick JS (2009) Genome-wide identification of long noncoding RNAs in CD8+ T cells. Journal of Immunology 182: 7738-7748.
195. Sunwoo H, Dinger ME, Wilusz JE, Amaral PP, Mattick JS and Spector DL (2009) MEN ε/β nuclear retained non-coding RNAs are upregulated upon muscle differentiation and are structural components of paraspeckles. Genome Research 19: 347-359.
196. Taft RJ, Glazov EA, Cloonan N, Simons C, Stephen S, Faulkner GJ, Lassmann T, Forrest ARR, Grimmond SM, Schroder K, Irvine K, Hume DA, Suzuki H, Orlando V, Carninci P, Arakawa T, Nakamura M, Kubosaki A, Hayashida K, Kawazu C, Murata M, Nishiyori H, Fukuda S, Kawai J, Daub CO, Hayashizaki Y and Mattick JS (2009) Tiny RNAs associated with transcription start sites in animals. Nature Genetics 41: 572-578.
197. Taft RJ, Glazov, EA, Lassmann T, Carninci P, Hayashizaki Y and Mattick JS (2009) Small RNAs derived from snoRNAs. RNA 15: 1233-1240.
198. Taft RJ, Kaplan C, Simons C and Mattick JS (2009) Evolution, biogenesis, and function of promoter-associated RNAs. Cell Cycle 8: 2332-2338.
199. Suzuki et al. The FANTOM consortium and RIKEN Genome Exploration Research Group (incl. Mattick JS) (2009) The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics 41: 553-562.
200. Webster RJ, Giles KM, Price KJ, Zhang PM, Mattick JS and Leedman PJ (2009) Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. Journal of Biological Chemistry 284: 5731-5741.
201. Aung HT, Harrison DK, Findlay I, Mattick JS, Martin NG and Carroll BJ (2010) Stringent programming of DNA methylation in humans. Twin Research & Human Genetics 13: 405-411.
John Mattick CV Page 18 202. de Hoon MDL, Taft RJ, Hashimoto T, Kanamori-Katayama M, Kawaji H, Kawano M, Kishima M, Lassmann T, Faulkner GJ, Mattick JS, Daub CO, Carninci P, Kawai J, Suzuki H and Hayashizaki Y (2010) Cross-mapping and the identification of editing sites in mature microRNAs in high-throughput sequencing libraries. Genome Research 20: 257-264.
203. Fernandez-Valverde SL, Taft RJ and Mattick JS. (2010) Dynamic isomiR regulation in Drosophila development. RNA 16: 1881-1888.
204. Jung C-H, Hansen MA, Makunin IV, Korbie DJ and Mattick JS (2010) Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data. BMC Genomics 11: 77.
205. Jung CH, Makunin IV and Mattick JS (2010) Identification of conserved Drosophila-specific euchromatin-restricted noncoding sequence motifs. Genomics 96: 154–166. [Cover picture].
206. Lai J, Lehman ML, Dinger ME, Hendy SC, Mercer TR, Seim I, Lawrence MG, Mattick JS, Clements JA and Nelson CC (2010) A variant of the KLK4 gene is expressed as a cis sense- antisense chimeric transcript in prostate cancer cells. RNA 16: 1156-1166.
207. Mattick JS (2010) Linc-ing long noncoding RNAs and enhancer function. Developmental Cell 19: 485-486.
208. Mattick JS (2010) RNA as the substrate for epigenome-environment interactions. Bioessays 32: 548–552.
209. Mattick JS (2010) The central role of RNA in the genetic programming of complex organisms. Anais da Academia Brasileira de Ciências 82: 933-939.
210. Mattick JS, Taft RJ and Faulkner GJ (2010) A global view of genomic information – moving beyond the gene and the master regulator. Trends in Genetics 26: 21-28.
211. Mazar J, Sinha S, Dinger ME, Mattick JS and Perera RJ (2010) Protein-coding and non- coding gene expression analysis in differentiating human keratinocytes using a three- dimensional epidermal equivalent. Molecular Genetics and Genomics 284: 1–9.
212. Mercer TR, Dinger ME, Bracken CP, Kolle G, Szubert JM, Korbie DJ, Askarian-Amiri ME, Gardiner BB, Goodall GR, Grimmond SM and Mattick JS (2010) Regulated post- transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Research 20: 1639-1650 [Cover picture].
213. Mercer TR, Qureshi IA, Gokhan S, Dinger ME, Guangyu L, Mattick JS and Mehler MF (2010) Long non-coding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neuroscience 11: 14.
214. Oldmeadow C, Mengersen K, Mattick JS and Keith JM (2010) Multiple evolutionary rate classes in animal genome evolution. Molecular Biology and Evolution 27: 942-953.
215. Qureshi IA, Mattick JS and Mehler MF (2010) Long non-coding RNAs in nervous system function and disease. Brain Research 1338: 20-35.
216. Taft RJ, Kaplan CD and Mattick JS (2010) Overlooked small RNA relationships and biogenesis models. Science, E-letter http://www.sciencemag.org/content/327/5963/335.short/reply#sci_el_12952.
217. Taft RJ, Pang KC, Mercer TR, Dinger ME and Mattick JS (2010) Noncoding RNAs: regulators of disease. Journal of Pathology 220: 126–139.
John Mattick CV Page 19 218. Taft RJ, Simons C, Nahkuri S, Oey H, Korbie DJ, Mercer TR, Holst J, Ritchie W, Wong JJ-L, Rasko JEJ, Rokhsar DS, Degnan BM and Mattick JS (2010) Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology 17: 1030-1034.
219. Amaral PP, Clark MD, Gascoigne DK, Dinger ME and Mattick JS (2011) lncRNAdb: a reference database for long noncoding RNAs. Nucleic Acids Research 39: D146-151.
220. Askarian-Amiri MA, Crawford J, French JD, Smith MA, Smart CE, Ru K, Mercer TR, Thompson EW, Lakhani SR, Vargas AC, Campbell IG, Brown MA, Dinger ME and Mattick JS (2011) SNORD-host RNA Zfas is a regulator of mammary development and a potential marker for breast cancer. RNA 17: 878-891.
221. Baillie JK, Barnett MW, Upton KR, Gerhardt DJ, Richmond TA, De Sapio F, Brennan PM, Rizzu P, Smith S, Fell M, Talbot RT, Gustincich S, Freeman TC, Mattick JS, Hume DA, Heutink P, Carninci P, Jeddeloh JA and Faulkner GJ (2011) Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479: 534-537.
222. Bracken CP, Szubert JM, Mercer TR, Dinger ME, Thomson DW, Mattick JS, Michael MZ and Goodall GR (2011) Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Research 39: 5658–5668.
223. Bredy TW, Lin Q, Wei W, Baker-Andresen D and Mattick JS (2011) MicroRNA regulation of neural plasticity and memory. Neurobiology of Learning and Memory 96: 89–94.
224. Buske FA, Mattick JS* and Bailey TL* (*Joint corresponding authors) (2011) Potential in vivo roles of nucleic acid triple helices. RNA Biology 8: 427-439.
225. Clark MB and Mattick JS (2011) Long noncoding RNAs in cell biology. Seminars in Cell and Developmental Biology 22: 366-376.
226. Clark MD, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, Gingeras TR and Mattick JS (2011) The reality of pervasive transcription PLoS Biology 9: e1000625.
227. Dinger ME, Gascoigne DK and Mattick JS (2011) The evolution of RNAs with multiple functions. Biochimie 93: 2013-2018.
228. Faunes F, Sánchez N, Moreno M, Olivares GH, Lee-Liu D, Almonacid L, Slater AW, Norambuena T, Taft RJ, Mattick JS, Melo F and Larrain J (2011) Regulated expression of transposable elements in neural tissues during Xenopus development. PLoS ONE 6: e22569.
229. Fernandez-Valverde SL, Taft RJ and Mattick JS (2011) miRNAs in β cell biology, insulin resistance, diabetes and its complications. Diabetes 60: 1825-1831.
230. Khaitan D, Dinger ME, Mazar J, Crawford J, Smith MA, Mattick JS* and Perera RJ* (*Joint corresponding authors) (2011) The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Research 71: 3852-3862.
231. Lopez Sanchez MIG, Mercer TR, Davies SMK, Shearwood AJ, Nygård KKA, Richman TR, Mattick JS, Rackham O and Filipovska A (2011) RNA processing in human mitochondria. Cell Cycle 10: 2904-2916.
John Mattick CV Page 20 232. Mattick JS (2011) Genome-sequencing anniversary. The genomic foundation is shifting. Science 331: 874.
233. Mattick JS (2011) Long noncoding RNAs in cell and developmental biology. Seminars in Cell and Developmental Biology 22: 327.
234. Mattick JS (2011) The central role of RNA in human development and cognition. FEBS Letters 585: 1600–1616.
235. Mattick JS (2011) The double life of RNA. Biochimie 93: viii–ix.
236. Mattick JS and Clark MB (2011) RNA lights up. Nature Biotechnology 29: 843-844.
237. Mercer TR, Neph S, Dinger ME, Crawford J, Smith MA, Shearwood AJ, Haugen E, Bracken CP, Rackham O, Stamatoyannopoulos JA, Filopovska A and Mattick JS (2011) The human mitochondrial transcriptome. Cell 146: 645-658 [Cover picture].
238. Mercer TR, Wilhelm D, Dinger ME, Soldà G, Korbie DJ, Glazov EA, Truong V, Schwenke M, Simons C, Matthaei KI, Saint RB, Koopman P and Mattick JS (2011) Expression of distinct RNAs from 3’ untranslated regions. Nucleic Acids Research 39: 2393-2403 [Cover picture].
239. Rackham O, Shearwood AJ, Mercer TR, Davies SM, Mattick JS and Filipovska A (2011) Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear- encoded proteins. RNA 17: 2085-2093.
240. Taft RJ, Hawkins PG, Mattick JS and Morris KV (2011) The relationship between tiRNAs and CTCF localization. Epigenetics & Chromatin 4: 13.
241. Thiagarajan RD, Cloonan N, Gardiner B, Mercer TR, Gabriel Kolle, Nourbakhsh E, Wani S, Tang DTP, Krishnan K, Georgas KM, Rumballe BA, Chiu HS, Steen JA, Mattick JS, Little MH, Grimmond SM (2011) Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling. BMC Genomics 12:441.
242. Wong CE, Zhao Y, Wang X-J, Croft LJ, Wang Z-H, Haerizadeh F, Mattick JS, Singh M, Carroll BJ and Bhalla P (2011) MicroRNAs in the shoot apical meristem of soybean. Journal of Experimental Botany 62: 2495-2506.
243. Barry G and Mattick JS (2012) The role of regulatory RNA in cognitive evolution. Trends in Cognitive Sciences 16: 497-503.
244. Buske FA, Bauer DC, Mattick JS and Bailey TL (2012) Triplexator: detecting nucleic acid triple helices in genomic and transcriptomic data. Genome Research 22: 1372-1381.
245. Clark MB, Johnston RL, Inostroza-Ponta M, Fox AH, Fortini E, Moscato P, Dinger ME and Mattick JS (2012) Genome-wide analysis of long noncoding RNA stability. Genome Research 22: 885-898.
246. Cossetti C, Mercer TR, Alpi E, Leonardi T, Drago D, Iraci N, Alfaro-Cervello C, Dinger ME, Dietmann S, Crawford J, Caddeo C, Verdugo MG, Bachi A, Mattick JS and Pluchino S (2012) Neural stem cells sort protein and RNA cargoes for export with exosomes in response to inflammation. Journal of Neuroimmunology 253: 127-127.
247. Gascoigne DK, Cheetham SW, Cattenoz PB, Clark MB, Amaral PP, Ryan J. Taft RJ, Dagmar Wilhelm D, Dinger ME and Mattick JS (2012) Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes. Bioinformatics 28: 3042-3050.
John Mattick CV Page 21 248. Mattick JS (2012) RNA driving the epigenetic bus. The EMBO Journal 31: 515-516.
249. Mattick JS (2012) RNA networks as digital control circuits of nuclear functions. In Genome Organization and Function in the Cell Nucleus (Rippe K, ed.), pp. 353-363, Wiley-VCH, Weinheim (ISBN: 3527326987).
250. Mattick JS (2012) Rocking the foundations of molecular genetics. Proceedings of the National Academy of Sciences USA 109: 16400–16401.
251. Mercer TR, Gerhardt DJ, Dinger ME, Crawford J, Trapnell C, Jeddeloh JA*, Mattick JS* and Rinn JL* (*Joint corresponding authors) (2012) Targeted RNA sequencing reveals the deep complexity of the human transcriptome. Nature Biotechnology 30: 99-104.
252. Nolan L, Beatson S, Croft L, Jones P, George A, Mattick JS, Turnbull L and Whitchurch CB (2012) Extragenic suppressor mutations that restore twitching motility to fimL mutants of Pseudomonas aeruginosa are associated with elevated intracellular cyclic AMP levels. Microbiology Open 1: 490-501.
253. Pineda SS, Wilson D, Mattick JS and King GF (2012) The lethal toxin from Australian funnel- web spiders is encoded by an intronless gene. PLoS ONE 7: e43699.
254. Schonrock N, Harvey RP and Mattick JS (2012) Long noncoding RNAs in cardiac development and pathophysiology. Circulation Research 111: 1349-1362.
255. Smart CE, Askarian Amiri ME, Wronski A, Dinger ME, Crawford J, Ovchinnikov DA, Vargas AC, Reid L, Simpson PT, Song S, Wiesner C, French JD, Dave RK, da Silva L, Purdon A, Andrew M, Mattick JS, Lakhani SR, Brown MA and Kellie S (2012) Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors. PLoS ONE 7: e40742.
256. Amaral PP, Dinger ME and Mattick JS (2013) Noncoding RNAs in homeostasis, disease and stress responses: an evolutionary perspective. Briefings in Functional Genomics 12: 254-278 (doi:10.1093/bfgp/elt016).
257. Buske FA, Bauer DC, Mattick JS and Bailey TL (2013) Triplex-Inspector: an analysis tool for triplex-mediated targeting of genomic loci. Bioinformatics 29: 1895-1897 (doi: 10.1093/bioinformatics/btt315).
258. Cattenoz PB, Taft RJ, Westhof E and Mattick JS (2013) Genome-wide identification of A>I RNA editing sites by inosine-specific cleavage. RNA 19: 257-270.
259. Cheetham SW, Gruhl F, Mattick JS* and Dinger ME* (*Joint corresponding authors) (2013) Long noncoding RNAs and the genetics of cancer. British Journal of Cancer 108: 2419–2425.
260. Clark MB, Choudhary A, Smith, MA, Taft RJ and Mattick JS (2013). The dark matter rises: the expanding world of regulatory RNAs. Essays in Biochemistry 54: 1–16 (doi: 10.1042/BSE0540001).
261. Li J-L, Mazar J, Zhong ZZ, Faulkner GJ, Govindarrajan SS, Zhang Z, Dinger ME, Meredith G, Adams C, Zhang S, Mattick JS, Ray A and Perera RJ (2013) Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network. Scientific Reports 3: 2962 (doi:10.1038/srep02962).
262. Liu G, Mattick JS and Taft RJ (2013) A meta-analysis of the genomic and transcriptomic composition of complex life. Cell Cycle 12: 127–138.
John Mattick CV Page 22 263. Liu GQ, Mercer TR, Shearwood AMJ, Siira SJ, Hibbs ME, Mattick JS, Rackham O and Filipovska A (2013) Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting. Cell Reports 5: 839-848 (http://dx.doi.org/10.1016/j.celrep.2013.09.036).
264. Marcellin E, Mercer TR, Licona-Casani C, Palfreyman RW, Dinger ME, Steen J, Gascoigne DK, Mattick JS and Nielsen LK (2013) Saccharopolyspora erythraea's genome is organised in high- order transcriptional regions mediated by targeted degradation at the metabolic switch. BMC Genomics 14: 15.
265. Mattick JS (2013) Probing the phenomics of noncoding RNA: Genetic knockout experiments on mice confirm that some long noncoding RNA molecules have developmental functions. eLife 2: e01968 (http://dx.doi.org/10.7554/eLife.01968).
266. Mattick JS and Dinger ME (2013) The extent of functionality in the human genome. The HUGO Journal 7:2 (doi:10.1186/1877-6566-7-2).
267. Mercer TR and Mattick JS (2013) Structure and function of long noncoding RNAs in epigenetic regulation. Nature Structural and Molecular Biology 20: 300-307.
268. Mercer TR and Mattick JS (2013) Understanding the regulatory and transcriptional complexity of the genome through structure. Genome Research 23: 1081-1088.
269. Mercer TR, Clark MB, Neph SJ, Edwards SL, Li G, Sandhu KS, Ruan Y, Nielsen L, Mattick JS* and Stamatoyannopoulos JA* (*Joint corresponding authors) (2013) DNaseI-hypersensitive exons co-localize with promoters and distal regulatory elements. Nature Genetics 45: 852–859 (doi: 10.1038/ng.2677).
270. Plummer PN, Balsara S, Umer B, Taft RJ, Ferro V, Mattick JS, Swarbrick A, McMillan N Mittal V and Mellick AS (2013) MicroRNAs as novel anti-angiogenesis therapeutic targets. Journal of Gene Medicine 15: 321-322.
271. Plummer PN, Freeman R, Taft R, Vider J, Sax M, Umer BA, Gao D, Johns CA, Mattick JS, Wilton SD, Ferro V, McMillan NA, Swarbrick A, Mittal V and Mellick AS (2013) MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells. Cancer Research 73: 341-352.
272. Rakoczy J, Fernandez-Valverde SL, Glazov EA, Wainwright EN, Sato T, Takada S, Combes AN, Korbie DJ, Miller D, Grimmond SM, Little MH, Asahara H, Mattick JS, Taft RJ and Wilhelm D (2013) MicroRNAs-140-5p/140-3p modulate Leydig cell numbers in the developing mouse testis. Biology of Reproduction 88 (143): 1-11 (doi: 10.1095/ biolreprod.113.107607).
273. Smith MA, Gesell T, Stadler P and Mattick JS (2013) Widespread purifying selection on RNA structure in mammals. Nucleic Acids Research 41: 8220-8236 (doi:10.1093/nar/gkt596).
274. Barry G, Briggs JA, Vanichkina DP, Poth EM, Beveridge NJ, Ratnu VS, Nayler SP, Nones K, Hu J, Bredy TW, Nakagawa S, Rigo F, Taft RJ, Cairns MJ, Blackshaw S, Wolvetang EJ and Mattick JS (2014) The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. Molecular Psychiatry 19:486–494 (doi: 10.1038/mp.2013.45).
275. Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cevello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao CJ, Muller W, Garcia-Verdugo JM, Mathivanan S, Bachi A, Enright AJ, Mattick JS and Pluchino S (2014) Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signalling in target cells. Molecular Cell 56: 193- 204 (doi: 10.1016/j.molcel.2014.08.020).
John Mattick CV Page 23 276. Liu PY, Erriquez D, Marshall GM, Tee AE, Polly P, Wong M, Liu B, Bell JL, Zhang XD, Giorgio Milazzo G, Belamy B. Cheung BB, Fox A, Swarbrick A, Hüttelmaier S, Kavallaris M, Perini G, Mattick JS, Dinger ME, and Liu T (2014) Effects of a novel long noncoding RNA, lncUSMycN, on N-myc expression and neuroblastoma progression. Journal of the National Cancer Institute 106 (7): dju113 (doi: 10.1093/jnci/dju113).
277. Mattick JS, Dziadek MA, Terrill BN, Kaplan W, Spigelman AD, Bowling FG, Dinger ME (2014) The impact of genomics on the future of medicine and health. Medical Journal of Australia 201: 17-20 (doi: 10.5694/mja13.10920).
278. Mazar J, Zhao W, Khalil AM, Lee B, Shelley J, Govindarajan SS, Yamamoto F, Ratnam M, Aftab MN, Collins S, Finck BN, Han X, Mattick JS, Dinger ME and Perera RJ. (2014) The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells. Oncotarget 5: 8959-8969 .
279. Mercer TR, Clark MB, Crawford J, Brunck ME, Gerhardt DJ, Taft RJ, Nielsen LK, Dinger ME and Mattick JS (2014) Gene discovery and quantification using targeted RNA Capture Sequencing. Nature Protocols 9: 989-1009 (doi:10.1038/nprot.2014.058).
280. Morris KV and Mattick JS (2014) The rise of regulatory RNA. Nature Reviews Genetics 15: 423– 437 (doi:10.1038/nrg3722).
281. Briggs JA, Wolvetang EJ, Mattick JS, Rinn JL and Barry G (2015) Mechanisms of long non- coding RNAs in mammalian nervous system development, plasticity, disease, and evolution. Neuron 88: 861-877 (doi: 10.1016/j.neuron.2015.09.045)
282. Clark MB, Mercer TR, Bussotti G, Leonardi T, Haynes KR, Crawford J, Le Cao KA, Brunck ME, Brown MA, Thomas GP, Taft RJ, Nielsen LK, Enright AJ, Mattick JS* and Dinger ME* (*Joint corresponding authors) (2015) Quantitative profiling of long noncoding RNAs with targeted RNA sequencing. Nature Methods 12: 339-342 (doi:10.1038/nmeth.3321).
283. Londin ER, Loher P, Telonis A, Quann K, Clark P, Jing Y, Hatzimichael E, Korino Y, Honda S, Lally M, Ramratnam B, Comstock C, Knudsen KE, Gomella L, Spaeth G, Hark L, Katz LJ, Witkiewicz A, Rostami A, Jimenez S, Hollingsworth M, Yeh JJ, Shaw C, McKenzie SE, Bray P, Nelson PT, Zupo S, Van Roosbroek K, Keating MJ, Calin G, Yeo CJ, Jimbo M, Cozzitorto JA, Brody J, Delgrosso K, Mattick JS, Fortina P and Rigoutsos I (2015) Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Proceedings of the National Academy of Sciences USA 112: E1106-E1115 (doi:10.1073/pnas.1420955112).
284. Mattick JS and Rinn JL (2015) Long noncoding RNA discovery and annotation. Nature Stuctural and Molecular Biology 22:5-7 (doi:10.1038/nsmb.2942).
285. Mercer TR, Clark MB, Andersen SB, Brunck ME, Haerty W, Crawford J, Taft RJ, Nielsen LK, Dinger ME and Mattick JS (2015) Genome-wide discovery of human splicing branchpoints. Genome Research 25: 290-303 (doi:10.1101/gr.182899.114).
286. Roadmap Epigenomics Consortium (including Mattick JS), Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA,
John Mattick CV Page 24 Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T & Kellis M (2015) Integrative analysis of 111 reference human epigenomes. Nature 518: 317-330 (doi:10.1038/nature14248).
287. Spadaro PA, Flavell CR, Widagdo J, Ratnu VS, Troup M, Ragan C, Mattick JS and Bredy TW (2015) Long noncoding RNA-directed epigenetic regulation of gene expression is associated with anxiety-like behavior in mice. Biological Psychiatry 78: 848-859 (doi: 10.1016/j.biopsych.2015.02.004).
288. Werner A, Piatek MJ and Mattick JS (2015) Transpositional shuffling and quality control in male germ cells to enhance evolution of complex organisms. Annals of the New York Academy of Sciences 1341: 156-163 (doi: 10.1111/nyas).
289. Bell CC, Amaral PP, Kalsbeek A, Magor GW, Gillinder KR, Tangermann P, di Lisio L, Cheetham SW, Gruhl F, Frith J, Tallack MR, Ru KL, Crawford J, Mattick JS, Dinger ME, Perkins AC (2016) The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation. Scientific Reports 6: 26657 (doi: 10.1038/srep26657).
290. Bussotti G, Leonardi T, Clark MB, Mercer TR, Crawford J, Malquori L, Notredame C, Dinger ME, Mattick JS, Enright AJ (2016) Improved definition of the mouse transcriptome via targeted RNA sequencing. Genome Research 26: 705-716 (doi: 10.1101/gr.199760.115).
291. Doble B, Schofield DJ, Tony Roscioli T and Mattick JS (2016) The promise of personalised medicine. The Lancet 387: 433–434 (doi: http://dx.doi.org/10.1016/S0140-6736(16)00176-8).
292. Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY (2016) RNA duplex map in living cells reveals higher order transcriptome structure. Cell 165: 1267-1279 (doi: 10.1016/j.cell.2016.04.028).
293. Schonrock N, Jonkhout N, Mattick JS (2016) Seq and you will find. Current Gene Therapy 16: 220-229. (http://www.ncbi.nlm.nih.gov/pubmed/27216913)
294. Zhao W, Mazar J, Lee B, Sawada J, Li J-L, Shelley J, Govindarajan S, Towler D, Mattick JS, Komatsu M, Dinger ME and Perera RJ (2016) The long non-coding RNA SPRIGHTLY regulates cell proliferation in primary human melanocytes. The Journal of Investigative Dermatology 136: 819–828 (doi: http://dx.doi.org/10.1016/j.jid.2016.01.018).
295. Deveson IW, Chen WY, Wong T, Hardwick SA, Andersen SB, Nielsen LK, Mattick JS, Mercer TR (2016) Representing genetic variation with synthetic DNA standards. Nature Methods 13, 784– 791 (doi: 10.1038/nmeth.3957).
296. Hardwick SA, Chen WY, Wong T, Deveson IW, Blackburn J, Andersen SB, Nielsen LK, Mattick JS, Mercer TR (2016) Spliced synthetic genes as internal controls in RNA sequencing experiments. Nature Methods 13, 792–798 (doi: 10.1038/nmeth.3958).
John Mattick CV Page 25 PUBLICATION STATISTICS (27 November 2016)
ISI Web of Science (Core Collection) Listed publications: 284 Total citations: 28501 Average citations per item: 100 h-index: 83
Scopus Listed publications: 279 Total citations: 31454 Average citations per item: 113 h-index: 87
Google Scholar Total citations: 43465 h-index: 99
PATENTS
1. Antigenic Preparation (Australian Patent No. 34979/84) Cloning and expression of Bacteroides nodosus fimbrial subunit genes in heterologous hosts as a basis for production of new vaccines against footrot. Inventors: J.S. Mattick and B.J. Anderson Filed: Australia and New Zealand 2-11-84.
2. Improved Antigenic Preparation (Australian Patent No. 50154/85; International PCT No. W086/02557) Morphogenetic expression of fimbrial subunit genes in Pseudomonas aeruginosa, or other compatible hosts, as a basis for the production of fimbrial antigens for vaccines against footrot and other type 4 fimbriate pathogens. Inventors: J.S. Mattick, B.J. Anderson and T.C. Elleman Filed: Australia, U.S.A., Europe, South Africa and New Zealand 29-10-85.
3. Peptide Production by Protein Engineering (Australian Patent No. 17049/88; International PCT No. W088/08430) Use of type 4 fimbrial subunits as a vehicle for the expression and export in recombinant bacterial cells of peptide sequences, such as the FMDV VP1 epitope 144-159, introduced by oligonucleotide-directed gene mutagenesis. Inventors: J.S. Mattick and P.A. Jennings Filed: Australia, U.S.A., Europe 27-4-87.
4. RNA Molecules and Uses thereof (United States Patent No. 61/043012; International PCT No. PCT/AU2009/000423) Non protein coding, small RNA molecules associated with gene regulatory activity Inventors: J.S. Mattick, R. Taft and P. Carninci Filed: Australia 07-04-2009
John Mattick CV Page 26 CONFERENCE PRESENTATIONS (*denotes invited speaker)
1. Mattick JS, Hall RM and Marzuki S (1975). Mitochondrial DNA replication in Saccharomyces cerevisiae - evidence for a functional association with membrane. Proc. Aust. Biochem. Soc. 8: 84.
2. Nagley P, Mattick JS and Hall RM (1977) Comparative studies on the genetic and molecular effects of drugs in inducing petite mutants in yeast. Proc. Aust. Biochem. Soc. 10: 62
3. Mattick JS, Murphy M and Smith SC (1977) Single-site mutations simultaneously affecting the mitochondrial ATPase and respiratory complexes in yeast. Proc. Aust. Biochem. Soc. 10: 97.
4. Zehner ZE, Mattick JS, Stuart R and Wakil SJ (1979) Fatty acid synthetase mRNA from vertebrates. Fed. Proc. 38: 299.
5. Stoops JD, Mattick JS, Zehner AE and Wakil SJ (1979) The regulation of fatty acid metabolism in animals. The Gordon Conference on Lipid Metabolism, Meriden, New Hampshire.
6. Mattick JS, Ahrens D and Wong H (1981) Monoclonal antibodies against chicken fatty acid synthetase. Fed. Proc. 40: 1596.
7. Tuskamoto Y, Wong H, Wakil SJ and Mattick JS (1982) The architecture of animal fatty acid synthetase. Fed. Proc. 41: 4421.
8. Mattick JS (1982) The molecular biology of fatty acid synthetase. The 4th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
9. Mattick JS, Stoops JK, Tsukamoto Y, Wong H and Wakil SJ (1982) The architecture and function of fatty acid synthetase. Proc. 12th International Congress of Biochemistry, Perth, Australia, p. 314.
10. Jennings PA, Both GW and Mattick JS (1984) Recombinant DNA approaches to vaccine production. Proc. 14th Australian Society for Immunology Meeting, Perth, Australia, p. 11.
11. *Mattick JS, Anderson BJ and Egerton JR (1985) Fimbriae of Bacteroides nodosus. Proc. Aust. Microbiol. Soc. 6: 130.
12. Mattick JS (1986) Morphogenetic expression of Bacteroides nodosus fimbriae in Pseudomonas aeruginosa. The 8th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
13. *Mattick JS (1986) Recombinant DNA-based vaccines against type 4 fimbriate pathogens. IUB Symposium 153. Genetic manipulation: its application and potential. Hanmer Springs, New Zealand.
14. *Mattick JS, Anderson BJ, Bills MM, Cox PT, Dalrymple BP, Egerton JR, Elleman TC, Finney K, Hoyne PA, Lehrbach P, McKern NM, Nicholas P, Schwartzkoff CL, Stewart DJ and Wright D (1986) Anaerobe to aerobe - the development of a recombinant DNA-based vaccine against ovine footrot. Proc. 7th Australian Biotechnology Conference, pp. 91-96.
15. Mattick JS (1986) Recombinant DNA-based vaccines against type 4 fimbriate pathogens. The Vaccine Conference, Lorne, Australia.
16. Mattick JS, Hobbs M, Anderson BJ, Bills MM, Cox PT and Dalrymple B (1987) The molecular genetics of Bacteroides nodosus fimbriae. The Gordon Conference on Bacterial Adhesion, Newport, Rhode Island, USA.
17. Dalrymple B, Cox PT, Hobbs M, Anderson BJ and Mattick JS (1988) Organization of the fimbrial gene region of Bacteroides nodosus: class I and class II strains and evidence for recombinational
John Mattick CV Page 27 exchange. The 10th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
18. Jennings PA, Bills MM, Elgin H, Finney KG, Irving DO and Mattick JS (1989) Peptide production by protein engineering using type 4 fimbriae as export vehicles. Proceedings 9th Australian Biotechnology Conference, pp. 507-510.
19. Mattick JS, Hobbs M, Cox P and Dalrymple BP (1989) Molecular genetics of type 4 fimbriae: Organization of the fimbrial gene region of Bacteroides nodosus. Proceedings 33rd Annual Conference of the Australian Biochemical Society, Gold Coast, Australia. Vol 21, p S19.
20. *Mattick JS (1989) Current perspectives in molecular genetics. Proceedings Australian Society of Microbiology Annual Scientific Meeting, Adelaide, Australia. Vol. 10(3), p. 401.
21. Hobbs M, Dalrymple BP and Mattick JS (1990) Transcriptional organization of the fimbrial gene region of Bacteroides nodosus. The 12th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
22. *Mattick JS (1990) An introduction to molecular biology. (Further education symposium: practical aspects of DNA technology) 26th Annual Meeting of the Australasian Society of Nephrology, Brisbane, Australia.
23. *Mattick JS (1990) Recent advances in molecular biology - applications in neuroscience. The Australian Neuroscience Society and the Australian Physiological and Pharmacological Society Combined Meeting, Brisbane, Australia.
24. Moore SS, Mattick JS and Hetzel DJS (1990) The use of microsatellites in gene mapping in cattle and sheep. The Australasian Gene Mapping Workshop, Sydney, Australia.
25. Cox PT, Egerton JR and Mattick JS (1990) Use of PCR to analyse a recombination hotspot immediately adjacent to the fimbrial subunit gene of class I isolates of Bacteroides nodosus. Proceedings Australian Society for MIcrobiology Annual Scientific Meeting, Launceston, Australia, Vol 11(3), p. 217.
26. Smith G, Young P and Mattick JS (1990) Development of a recombinant BHV-1 vaccine and vaccine delivery system. 9th Australian Biotechnology Conference, Gold Coast, Australia.
27. Hobbs MH, Whitchurch CB, Livingston SP and Mattick JS (1991) Characterization of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria. Boden Research Conference on Molecular Analysis of Bacterial Pathogenesis, Thredbo, Australia.
28. Mattick JS, Hobbs M, Cox PT and Dalrymple BP (1991) Organization of the fimbrial gene region of Dichelobacter nodosus: class I and class II strains. Boden Research Conference on Molecular Analysis of Bacterial Pathogenesis, Thredbo, Australia.
29. Whitchurch CB, Hobbs M, Livingston SP, Krishnapillai V and Mattick JS (1991) Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria. The 13th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
30. Gobius KS, Barnard R, Mattick JS and Waters MJ (1991) Site-directed mutagenesis of the rabbit growth hormone receptor; identification of residues essential for growth hormone binding. Proceedings of the US Endocrine Society, Vol. 73, p. 248.
31. *Mattick JS (1991) Commercialising research results in biotechnology. Round Table Meeting on Biotechnology in a Developing Economy, Kuala Lumpur, Malaysia.
John Mattick CV Page 28 32. Mattick JS, Hobbs M, Whitchurch CB and Livingston SP (1991) Biogenesis and function of type 4 fimbriae in Pseudomonas aeruginosa: a specialised protein export system. Proceedings Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Queensland Vol 12(3), p. 286.
33. Hobbs M, Collie ESR, Livingston SP and Mattick JS (1992) A two-component transcriptional regulatory system controlling expression of Pseudomonas aeruginosa type 4 fimbriae. The 14th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
34. Whitchurch CB, Hobbs M and Mattick JS (1992) Molecular genetics of bacterial pathogenesis: genes involved in the assembly of cell surface macromolecular complexes. The 14th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
35. Lunn DP, Arnold JM, Mattick JS and Don RH (1992) In vitro analysis of the interactions between the promoter region of the murine Hox-3.1 gene and the homeodomain it encodes. The 14th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
36. McDonald LE, Paterson CA, Mattick JS and Don RH (1992) Identification of developmentally regulated genes using a gene trap reporter construct in mouse embryonic stem cells. The 14th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
37. Hobbs M, Collie ESR, Livingston SP and Mattick JS (1992) A two-component transcriptional regulatory system controlling expression of Pseudomonas aeruginosa type 4 fimbriae. Proceedings Australian Society for Microbiology XX Annual Scientific Meeting, Sydney, Australia, Vol 13 (No. 3), A218.
38. *Mattick JS, Hobbs M, Collie ESR, Free PD and Livingston SP (1992) Sensor-regulator networks in bacterial pathogenesis: a two-component transcriptional regulatory system controlling expression of Pseudomonas aeruginosa type 4 fimbriae. Proceedings of the Genetics Society of Australia Annual Scientific Meeting, Brisbane, Australia.
39. Hobbs M, Livingston SP, Collie ESR, Free PD and *Mattick JS (1992) Molecular genetics of host colonization by Pseudomonas aeruginosa: the regulatory hierarchy controlling expression of type 4 fimbriae. Proceedings of the Second Annual Queenstown Molecular Meeting, Queenstown, New Zealand, p. 13.
40. *Mattick JS (1992) Genome analysis - a framework for the future in biological research and biotechnology. Australian and New Zealand Association for the Advancement of Science, Brisbane, Australia.
41. *Mattick JS (1994) One gene may not equal one protein: RNA-based gene regulation and the significance of introns in eukaryotic evolution. Proceedings of 38th Annual Meeting of the Australian Society for Biochemistry and Molecular Biology, Gold Coast, Australia (Symposium 20-1).
42. Wood GM, Marrs CF, Mattick JS and McCormack JG (1994) The absence of type 4 fimbriae in Moraxella (Branhamella) cattarrhalis. Proceedings Australian Society for Microbiology XX Annual Scientific Meeting, Melbourne, Australia.
43. *Mattick JS (1994) Do genes encode only proteins? The significance of introns and RNA-based gene regulation in eukaryotic development. Second Annual Scientific Meeting of the Australian Vascular Biology Society, Hahndorf, Australia.
44. Mattick JS (1995) Do genes encode only proteins? The significance of introns and RNA-based gene regulation in eukaryotic development. The 17th Annual Conference on the Organization and Expression of the Genome, Lorne, Australia.
John Mattick CV Page 29 45. Kennedy HD, Wood SA and *Mattick JS (1995) The family of genes controlling alternative splicing in mammals. The 8th International Congress on Isozymes - Gene Families: Structure, Function, Genetics and Evolution, Brisbane, Australia.
46. *Mattick JS (1995) A-Z is not enough: the molecular genetics of type 4 fimbriae in Pseudomonas aeruginosa and related pathogens. The 3rd Australian Conference on Molecular Analysis of Bacterial Pathogens, Marysville, Australia.
47. *Mattick JS (1995) Intron-exon structure and the evolution of parallel processing. Michael J. D. White Memorial Lecture, Genetics Society of Australia, Canberra, Australia.
48. Alm RA and *Mattick JS (1995) Genes involved in the biogenesis and function of type 4 fimbriae in Pseudomonas aeruginosa. Workshop on Type 4 pili - biogenesis, adhesins, protein export, and DNA import, Schloß Ringberg, Germany.
49. *Mattick JS (1996) Genome research - the information superhighway of biotechnology. 10th International Biotechnology Symposium, Sydney, Australia. Abstract S6-5, p. 42.
50. Wood SA and Mattick JS (1996) Fam is a novel ubiquitin-specific protease expressed during postimplantation mouse development. Australian and New Zealand Society for Cell Biology Meeting, Brisbane, Australia.
51. *Mattick JS (1996) Genome research and drug discovery. 2nd Australia-Japan Symposium on Drug Design and Development, Cairns, Australia.
52. *Mattick JS (1997) The Australian Genome Research Facility. 2nd International Strategy Meeting on Human Genome Sequencing, Hamilton, Bermuda.
53. Whitchurch CB, Darzins A, Alm RA, Hobbs M, Martin PR, Nourse CR, Watson A and Mattick JS (1997) Pseudomonas aeruginosa genes pilL, chpA and chpB are necessary for type 4 fimbrial biosynthesis and twitching motility. 97th General Meeting of the American Society of Microbiology, Miami USA. Abstract D-41, p. 214.
54. *Mattick JS, Whitchurch CB, Martin PR, Alm RA and Hobbs M (1997) Regulatory pathways affecting the biogenesis and function of type 4 fimbriae in Pseudomonas aeruginosa. VI International Meeting on Pseudomonas: Molecular Biology and Biotechnology, Madrid, Spain.
55. *Mattick JS, Alm R, Whitchurch CB, Martin R and Hobbs M (1998) The molecular genetics of type 4 fimbriae in Pseudomonas aeruginosa and related bacterial pathogens. 9th National Biotechnology Seminar, Penang, Malaysia.
56. Comolli J, Waite L, Hauser A, Whitchurch CB, Mattick JS and Engel J (1998) Pilin function is necessary for Pseudomonas aeruginosa cytotoxicity and invasion of epithelial cells. 98th General Meeting of the American Society of Microbiology, Abstract B-81, p. 69.
57. *Mattick JS (1998) Genomics in Australia. Conference on Biological Informatics, Australian Academy of Science, Canberra, Australia.
58. *Mattick JS (1998) The implications of the human genome project for medicine and healthcare in the 21st century. Australian Pharmaceutical Manufacturers Association Conference, Canberra, Australia.
59. *Mattick JS (1998) Genomics and genetics in drug discovery and drug delivery. Third Australia / Japan Symposium on Drug Design and Development, Tokushima, Japan.
60. *Mattick JS (1998) Intron function and eukaryote evolution. Queenstown 1998 Molecular Biology Meeting, Queenstown, New Zealand.
John Mattick CV Page 30 61. *Mattick JS (1998) Genomics and genetics - from bacteria to humans. Joint Meeting of the New Zealand Microbiology Society and The New Zealand Society for Biochemistry and Molecular Biology, Masterton, New Zealand.
62. *Mattick JS (1998) Host colonisation by Pseudomonas aeruginosa. Joint Meeting of the New Zealand Microbiology Society and the New Zealand Society for Biochemistry and Molecular Biology, Masterton, New Zealand.
63. Beatson SA, Whitchurch CB and *Mattick JS (1998) Whole genome analysis of Pseudomonas aeruginosa: identification of novel genes and pathways. Joint Meeting of the New Zealand Microbiology Society and the New Zealand Society for Biochemistry and Molecular Biology, Masterton, New Zealand.
64. Croft LJ, Huang B, Blakeley RL, Beatson SA, Whitchurch CB and Mattick JS (1999) Annotation of the Pseudomonas aeruginosa PA01 genome. Human Genome Meeting 1999 (HGM’99), Brisbane, Australia.
65. Croft LJ, Whitchurch CB, Beatson SA, Blakeley RL, Huang B and *Mattick JS (1999) Exploring the Pseudomonas aeruginosa genome. Abstract S31. Pseudomonas’99: biotechnology and pathogenesis. American Society for Microbiology, Maui, USA.
66. Whitchurch CB, Young M, Leech A, Semmler A and Mattick JS (1999) The molecular genetics of type 4 fimbriae and twitching motility in Pseudomonas aeruginosa. Abstract S41. Pseudomonas’99: biotechnology and pathogenesis. American Society for Microbiology, Maui, USA.
67. Clark F, Croft LJ, Schandorff S, Burrage K and Mattick JS (1999) ISIS – the intron database: a glimpse of intron function. Abstract S-18-03. Combio ’99 (43rd Annual Meeting of the Australian Society for Biochemistry and Molecular Biology, 18th Annual Meeting of the Australian and New Zealand Society for Plant and Developmental Biology, and the 39th annual Meeting of the Australian Society of Plant Physiologists), Gold Coast, Australia.
68. Croft LJ, Beatson SA, Whitchurch CB, Blakeley RL, Huang B and Mattick JS (1999) One approach to developing a bacterial genome database. Abstract S-25-02. Combio ’99 (43rd Annual Meeting of the Australian Society for Biochemistry and Molecular Biology, 18th Annual Meeting of the Australian and New Zealand Society for Plant and Developmental Biology, and the 39th annual Meeting of the Australian Society of Plant Physiologists), Gold Coast, Australia.
69. McCarthy F, Smith GA and Mattick JS (1999) Molecular characterisation of Australian bovine enterovirus. Poster VP20.27. ICV Conference, Sydney, Australia.
70. Kennedy HD, French J, Verhagen A and Mattick JS (1999) The ras-GTPase-activating protein SH3-domain-binding family of proteins (G3BPs): implications in ras-GAP120 signalling to RNA stability and cancer progression. Abstract S-33-03. Combio ’99 (43rd Annual Meeting of the Australian Society for Biochemistry and Molecular Biology, 18th Annual Meeting of the Australian and New Zealand Society for Plant and Developmental Biology, and the 39th annual Meeting of the Australian Society of Plant Physiologists), Gold Coast, Australia.
71. Utama B, Kennedy HD, Ru K and Mattick JS (1999) Isolation and preliminary characterization of a novel nucleolar protein. Abstract P-W-51. Combio ’99 (43rd Annual Meeting of the Australian Society for Biochemistry and Molecular Biology, 18th Annual Meeting of the Australian and New Zealand Society for Plant and Developmental Biology, and the 39th annual Meeting of the Australian Society of Plant Physiologists), Gold Coast, Australia.
72. Croft LJ, Whitchurch CB, Beatson SA, Blakeley RL, Huang B and *Mattick JS (1999) Exploring the Pseudomonas aeruginosa genome. Abstract OP-A28, p. 433. 11th National Biotechnology Seminar, Melaka, Malaysia.
John Mattick CV Page 31 73. Croft LJ, Schandorff S, Clark F, Burrage K, Arctander P and Mattick JS (2000) ISIS, an intron information system, and the prevalence of alternative splicing in the human genome. Human Genome Meeting 2000 (HGM’2000), Vancouver, Canada.
74. *Mattick JS (2000) After the human genome project: implications for medicine, healthcare and humanity in the 21st century. Abstract 125, p. 38. The 11th International Congress of Endocrinology (ICE 2000), Sydney, Australia.
75. Erova T, Whitchurch CB, Leech AJ, Mattick JS and Wozniak DJ (2000) Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbriae-mediated twitching motility but not for alginate production. 2nd Euroconference on Bacterial Neural Networks, Dublin, Ireland.
76. Whitchurch CB, Young MD, Leech AJ, Semmler ABT and Mattick JS (2000) Complex regulatory networks in Pseudomonas aeruginosa pathogenesis. Australian Society for Microbiology Annual General Meeting, Cairns, Australia.
77. Beatson SA, Croft LJ, Whitchurch CB, Huang B, Blakeley RL and Mattick JS (2000) The Pseudomonas aeruginosa Interactive Genome Database: a platform for genomic analysis. Australian Society for Microbiology, Annual General Meeting, Cairns, Australia.
78. Young MD, Mattick JS and Whitchurch CB (2000) Involvement of the Chp signal transduction pathway in control of twitching motility and production of autoinducers and multiple virulence factors in Pseudomonas aeruginosa. Australian Society for Microbiology, Annual General Meeting, Cairns, Australia.
79. *Mattick JS (2001) Twitching motility. Keystone Symposium: Microbial interactions with their environment: genome approaches. Taos, USA.
80. *Mattick JS (2001) Is there an intrinsic difference between eukaryotes and prokaryotes in their genetic operating system: The evolution of controlled multitasked molecular networks: a role for introns and other noncoding RNAs. Keystone Symposium: Microbial interactions with their environment: genome approaches. Taos, USA.
81. *Mattick JS (2001) Functional genomics, RNomics and computational biology: exploring the genetic and molecular basis of phenotypic complexity and diversity. Asia-Pacific International Molecular Biology Meeting, Tokyo, Japan.
82. *Mattick JS (2001) Biological software. Commercialising Health Innovations Forum / Australian Biotechnology Association (CHIF/ABA) Conference, Sydney, Australia.
83. *Mattick JS (2001) The human genome project – implications for cancer. Centenary Surgical Oncology Meeting 2001, Princess Alexandra Hospital, Brisbane, Australia.
84. *Mattick JS (2001) The role of introns and other noncoding RNAs in the evolution and development of complex organisms. European Society of Evolutionary Biology Meeting 2001, Åarhus, Denmark.
85. *Mattick JS (2001) The demonisation of genetics. The Australian Institute of Health, Law and Ethics 5th Annual Conference, Melbourne, Australia (Plenary: Kirby Oration).
86. *Mattick JS (2001) Molecular genetic networks and the architecture of eukaryotic complexity. Ninth Frank and Bobbie Fenner Conference in Medical Research - Bioinformation Science, Australian Academy of Science, Canberra.
87. Beatson SA, Whitchurch CB and Mattick JS (2001) Pseudomonas aeruginosa twitching motility requires vfr but not the las or rhl quorum sensing systems. 101st Annual General Meeting of the American Society for Microbiology, Orlando, USA.
John Mattick CV Page 32 88. Erova T, Whitchurch CB, Leech AJ, Mattick JS and Wozniak DJ (2001) Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbriae-mediated twitching motility but not for alginate production. 101st Annual General Meeting of the American Society for Microbiology, Orlando, USA.
89. Whitchurch CB, Beatson SA, Sargent JL, Young MD, Engel JN and Mattick JS (2001) Type IV fimbrial biogenesis and twitching motility are coordinately regulated with the production of multiple virulence factors of Pseudomonas aeruginosa. Gordon Research Conference - Molecular Mechanisms of Microbial Adhesion, Salve Regina University, Newport, USA.
90. Nouwens AS, Beatson SA, Whitchurch CB, Young MD, Schweizer HP, Willcox MMDP, Walsh BJ, Mattick JS and Cordwell SJ (2001) Identification of extracellular proteins in Pseudomonas aeruginosa via proteomics: invasive, cytotoxic and quorum sensing aspects. Pseudomonas 2001 - Eighth International Congress on Pseudomonas: Biotechnology and Pathogenesis, Brussels, Belgium.
91. Beatson SA, Whitchurch CB, Commoli JC, Kang PJ, Mattick JS and Engel JN (2001) FimL co- ordinates twitching motility, cytotoxicity and quorum sensing in Pseudomonas aeruginosa via control of the virulence factor regulator, Vfr. Pseudomonas 2001 - Eighth International Congress on Pseudomonas: Biotechnology and Pathogenesis, Brussels, Belgium.
92. Whitchurch CB, Beatson SA, Young MD, Sargent JL, Leech AJ, Engel JN, Free PD, Wozniak D, Jaeger K-E and *Mattick JS (2001) The co-ordinate regulation of twitching motility and other virulence factors in Pseudomonas aeruginosa. Pseudomonas 2001 - Eighth International Congress on Pseudomonas: Biotechnology and Pathogenesis, Brussels, Belgium.
93. *Mattick JS (2001) Perspectives in genomics. PHIMR/IRD Reproductive Genomics Symposium, Melbourne, Australia.
94. *Mattick JS (2002) An elephant is not like E. coli: the role of non-coding RNA in the evolution and development of complex organisms. Annual Conference of the Indian Society of Developmental Biology, Kanpur, India.
95. *Mattick JS (2002) The control architecture of the human genome. BioScience Asia 2002, Taipei, Taiwan.
96. *Mattick JS (2002) Noncoding RNA – the secret of eukaryotic complexity. The 2nd Rudbeck Symposium on Molecular Medicine. University of Uppsala, Uppsala, Sweden (Plenary).
97. *Mattick JS (2002) Maximizing the value of genomic information: Modulation of RNA targets and RNA-based regulatory architecture. BIO’2002 Conference, Toronto, Canada.
98. *Mattick JS (2002) Current ethical landscape and issues for biotechnology in Australia. BIO’2002 Conference, Toronto, Canada.
99. *Mattick JS (2002) The role of introns and other noncoding RNAs in the evolution and development of complex organisms. Molecular Evolution Conference (jointly organized by the International Society of Molecular Evolution and the Society for Molecular Biology and Evolution), Sorrento, Italy.
100. *Mattick JS (2002) Non-coding RNA in human genomic programming – the control architecture of a complex system. Chromosomes to Genes Conference, Women’s and Children’s Hospital, Adelaide, Australia.
101. Cavicchioli R, Curmi P, Davies J, Giaquinto L, Goodchild A, Guilhaus M, Mazard S, Saunders N, Thomas T, Wasinger V, Davies J, Kuczek E, Mattick JS, Slade R, Franzmann P, Aerts A, Dehal P, Detter C, Glavina T, Kadner K, Lucas S, Larimer F, Bench S, Gates C, Feldman R, Boone D,
John Mattick CV Page 33 Rusterholtz K and Sowers K (2002) Genomic studies of psychrophiles. 151st Ordinary Meeting of the Society for General Microbiology, Loughborough, UK.
102. Aung H, Harrison D , Findlay I, Mattick JS, Martin, N and Carroll, BJ (2002) Stringent genetic programming of DNA methylation in humans. 7th Australian Twin Registry Conference and 3rd Australasian Human Gene Mapping Meeting, Hobart, Australia.
103. *Mattick JS (2003) Programming of complex organisms: the hidden layer of noncoding RNA. Lorne Protein Conference, Lorne, Australia (Plenary).
104. *Mattick JS (2003) The autopoietic programming of complex organisms: the hidden layer of noncoding RNA. Bioinformatics 2003, SocBIN – Society for Bioinformatics in the Nordic Countries, Helsinki, Finland (Plenary).
105. *Mattick JS (2003) Programming of the autopoietic development of complex organisms: the hidden layer of noncoding RNA. 11th International Conference on Intelligent Systems for Molecular Biology, Brisbane, Australia (Plenary).
106. Geard N, Wiles J and Mattick JS (2003) Modeling the role of small RNAs in gene regulation. 11th International Conference on Intelligent Systems for Molecular Biology, Brisbane, Australia.
107. Tonkes B, Wiles J and Mattick JS (2003) Controling complexity in biological networks. 11th International Conference on Intelligent Systems for Molecular Biology, Brisbane, Australia.
108. *Mattick JS (2003) Genetic programming of complex organisms: the hidden layer of noncoding RNA. International Congress of Genetics, Melbourne, Australia.
109. *Mattick JS (2003) Genetic programming of complex organisms: the hidden layer of noncoding RNA. IXth International Congress on Inborn Errors of Metabolism, Brisbane, Australia (Plenary).
110. *Mattick JS (2003) Efference RNA-mediated regulatory networks encoded in exons and introns - a digital feed-forward system controlling differentiation and development. Symposium-05-02 (p. 30 Abstract Book), Combio2003, Melbourne, Australia.
111. *Mattick JS (2003) Genomic programming of complex organisms: the hidden layer of noncoding RNA. Okinawa International Symposium: New Horizons in Molecular Sciences and Systems - An Integrated Approach, Nara, Japan (Plenary).
112. *Mattick JS (2003) The hidden layer of efference RNA-mediated regulatory networks: a digital feed-forward system underpinning the evolution and development of complex organisms. 2003 Congress on Evolutionary Computation, Canberra, Australia (Plenary).
113. *Mattick JS (2003) Genomic programming of complex organisms: the hidden layer of noncoding RNA. BioInfoSummer 2003: Mathematical, statistical and computational challenges in bioinformatics, Australian National University, Canberra (Plenary).
114. Ravasi T, Wells C, Ru K, Mattick JS, Sweet MJ, Himes R, and Hume DA (2004) Noncoding RNAs: are they real? Lorne Genome Conference, Lorne, Australia.
115. *Mattick JS (2004) The hidden layer of noncoding RNA: a digital control system underpinning mammalian development and diversity. HGM’2004, Berlin, Germany.
116. *Mattick JS (2004) Programming of the autopoietic development of complex organisms: the hidden layer of noncoding RNA. ISAC (International Society of Analytical Cytology) International Congress, Montpellier, France (Closing Plenary: Robert Hooke Distinguished Lecture).
117. *Mattick JS (2004) Endogenous programming of mammalian development: the hidden layer of noncoding RNA-mediated regulatory networks. Gordon Conference on Mammalian Gametogenesis and Embryogenesis, New London, Connecticut, USA.
John Mattick CV Page 34 118. Makunin IV, Stephen S, Pheasant M, Bejerano G, Kent JW, Haussler D, and Mattick JS (2004) Extremely conserved non-coding sequences in vertebrate genomes. Proceedings of the Fourth International Conference on Bioinformatics of Genome Regulation and Structure, Novosibirsk, Russia, Vol 1, pp. 138-140.
119. *Mattick JS (2004) The regulatory architecture of the human genome. Nutrition Society of Australia 28th Annual Scientific Meeting in conjunction with the Nutrition Society of New Zealand and the International Congress of Clinical Nutrition, Brisbane, Australia (Plenary).
120. *Mattick JS (2004) The genomic programming of animal growth and development. Horizons in Livestock Science, Gold Coast, Australia (Plenary).
121. *Mattick JS (2004) The genomic programming of complex organisms: the hidden layer of noncoding RNA. GSAC XVI, Washington D.C., USA (Plenary).
122. *Mattick JS (2004) The genomic programming of complex organisms: the hidden layer of noncoding RNA. The Fifth Princess Chulabhorn International Science Congress: Evolving Genetics and its Global Impact, Bangkok, Thailand, Vol. 1, pp109-111 (Plenary).
123. *Mattick JS (2004) The genomic programming of complex organisms: the hidden layer of noncoding RNA. 17th FAOBMB Symposium/ 2nd IUBMB Special Meeting/ 7th A-IMBN Conference, Bangkok, Thailand (Plenary).
124. Pang KC, Ravasi T, Suzuki H, Pheasant M, Stephen S, Stanley S, Ru K, Chen W, Hume DA, Hayashizaki Y, and Mattick JS (2004) The hidden layer of noncoding RNAs: is this what distinguishes mouse from man? Human Genetics Organisation (HUGO) Pacific Meeting, Singapore.
125. Suzuki H, Ravasi T, Pang KC, Katayama S, Furuno M, Okunishi R, Fukuda S, Ru K, Frith MC, Gongora M, Grimmond SM, Hume DA, Hayashizaki Y and Mattick JS (2005) Experimental validation of the regulated expression of large numbers of noncoding RNAs from the mouse genome. Systems Biology: global regulation of gene expression Cold Spring Harbor Laboratory, New York, USA.
126. *Mattick JS (2005) Information in Biological systems. AMSI Winter School in Bioinformatics, University of Queensland, Brisbane, Australia.
127. *Mattick JS (2005) The hidden layer of noncoding RNA in the evolution and development of complex organisms. Annual Meeting of the Society for Molecular Biology and Evolution (MBE’05), Auckland, New Zealand.
128. *Mattick JS (2005) Genomic programming of complex organisms: the hidden layer of noncoding RNA. International Workshop on Encoding Information in DNA Sequences, Nara, Okinawa, Japan (Plenary).
129. *Mattick JS (2005) The hidden layer of digital RNA programming in complex organisms. CSIRO Conference on Emerging Science: Small RNAs, Canberra, Australia.
130. *Mattick JS (2005) The hidden layer of noncoding RNA in the evolution and development of complex organisms. 15th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand (Plenary).
131. *Mattick JS (2005) RNA regulation: a new genetics. 9th International Conference on Environmental Mutagens and 36th Annual Meeting of The Environmental Mutagen Society (Abstract No. 454, p. 142), San Francisco, USA (Plenary).
132. *Mattick JS (2005) Noncoding RNA-mediated regulatory networks in mammalian differentiation and development. Y Chromosome and Male Germ Cell Biology in Health and Diseases in the
John Mattick CV Page 35 Post Genomic Era (NICHD/NIH sponsored meeting, Abstract p. 14). Asilomar, California, USA (Plenary).
133. *Mattick JS (2005) The hidden layer of noncoding RNA in the genetic programming of complex organisms. (Abstract pp. 47-49 Proceedings) 77th Annual Meeting of Japan Society of Genetics, Tokyo, Japan (Plenary).
134. *Mattick JS (2005) The role of noncoding RNA in evolution and development of complex organisms. 6th Anton Dohrn Workshop on Evolutionary Genomics, Ischia, Naples, Italy (Plenary).
135. Pang KC, Gardiner B, Crowe M, Frith MC, Grimmond SM, Mattick JS and Chen W (2005) The hidden layer of noncoding RNA in killer T cells. The 35th Australasian Society for Immunology Annual Scientific Meeting, Melbourne, Australia.
136. *Mattick JS (2006) RNA regulatory networks in animal and plant development, epigenetic memory and disease. 2006 NZBio Conference, Auckland, New Zealand.
137. *Mattick JS (2006) Issues arising from genomic science. Australasian Law Reform Agencies Conference, Sydney, Australia.
138. *Mattick JS (2006) Legal, philosophical and social Issues in genetics and biotechnology. Supreme and Federal Court Judges Conference, Brisbane, Australia (Plenary).
139. Pang KC, Frith MC, Ravasi T, Gardiner B, Dinger ME, Gongora MM, Crowe M, Ru K, Hume DA, Hayashizaki Y, Grimmond SM, Chen W and Mattick JS (2006) Evolution and developmental expression of noncoding RNAs. Lorne Genome Conference (Promega Student Poster Award), Lorne, Australia.
140. Dinger ME, Glazov EA, Pang KC, Crowe M and Mattick JS (2006) Identification of differentially expressed ncRNAs involved in myoblast differentiation using a novel ncRNA microarray. Lorne Genome Conference, Lorne, Australia.
141. Tajul-Arifin K and Mattick JS (2006) Evolutionary approach to identifying domain subtypes. 4th Asia-Pacific Bioinformatics Conference (APBC2006), Taiwan.
142. *Mattick JS (2006) The hidden layer of digital RNA signaling in complex organisms. RNA and Imaging Symposium of the DFG Research Training Group 886: Molecular imaging methods for the analysis of gene and protein expression. Kirchhoff-Institut für Physik, University of Heidelberg, Heidelberg, Germany (Opening Plenary).
143. *Mattick JS (2006) Genomic information and eukaryotic complexity. 3rd International Conference on Legume Genomics & Genetics, Brisbane, Australia (Plenary).
144. Perkins A, Bruce S, Dinger ME, Gardiner B, Steptoe A, Burke L, Mattick JS and Grimmond SM (2008) Transcription factors, non-coding RNAs and ES cell differentiation in vitro and in vivo. Transgenic Research (Meeting Report) 15: 778 (ISSN: 0962-8819).
145. Mattick JS, Dinger ME, Pheasant M, Glazov EA, Pang KC, Croft LJ, Makunin IV, Frith MC, Simons C, Gagen MJ, Taft RJ, Solda G, Nahkuri S, Mercer TR, Stanley S and Stephen S (2006) Evolution, identification and expression of non-coding RNAs in animals. RNA Symposium, Cold Spring Harbor, USA.
146. *Mattick JS (2006) The hidden layer of non-coding RNA in the evolution and development of complex organisms. 48th Karolinska Institutet Nobel Conference: "The Functional RNA World," Stockholm, Sweden (Plenary).
John Mattick CV Page 36 147. *Mattick JS (2006) Genetic information and biological complexity. ASM 2006 (2006 Annual Scientific Meeting & Exhibition of the Australian Society for Microbiology), Gold Coast, Australia (Opening Plenary).
148. *Mattick JS (2006) Ethics and ideologies in biology and medicine. 2006 ABA Public Lecture: ABA/ANZIHLE 2006 Conference (11th conference of the Australasian Bioethics Association incorporating the 10th annual conference of the Australian & New Zealand Institute of Health, Law & Ethics Issues), Brisbane, Australia (Opening Plenary).
149. Dinger ME, Glazov EA, Pang KC, Pheasant M, Croft LJ and *Mattick JS (2006) Bioinformatic identification and experimental validation of functional noncoding RNAs. 11th International Congress of Human Genetics, Brisbane, Australia.
150. *Mattick JS (2006) The role of non-coding RNA in human development. Endocrine Society of Australia (ESA) & Society for Reproductive Biology (SRB) Annual Scientific Meeting, Gold Coast, Australia (Opening Plenary).
151. *Mattick JS (2006) Recruiting and retaining the best. International Network of Research Management Societies (INORMS) Inaugural Conference, Brisbane, Australia.
152. *Mattick JS (2006) The genomes of complex organisms encode an RNA machine that controls differentiation and development. 9th A-IMBN Conference and 16th MSMBB Scientific Meeting, Kuala Lumpur, Malaysia (Plenary).
153. Dinger ME, Pang KC, Bruce S, Perkins AC, Grimmond SM and *Mattick JS (2006) Dynamic expression of noncoding RNA during mammalian differentiation and development. ComBio2006 (Joint Annual Conferences of the Australian Society for Biochemistry & Molecular Biology, the Australian Society of Plant Scientists, the Australian Physiological Society, the Australia and New Zealand Society for Cell and Developmental Biology, the New Zealand Society for Biochemistry and Molecular Biology and the New Zealand Society of Plant Physiologists), Brisbane, Australia.
154. *Mattick JS, Pheasant M, Dinger ME, Pang KC, Makunin IV and Simons C (2006) The central role of noncoding RNA in the evolution and development of complex organisms. Marine Genomics, Sorrento, Italy (Plenary).
155. *Mattick JS (2006) The hidden layer of noncoding RNA in the epigenetic control of human differentiation and development. Australian Health and Medical Research Congress, Melbourne, Australia (Plenary: MEPSA George Christie Lecture).
156. *Mattick JS (2006) The majority of the human genome encodes a hidden RNA regulatory system that controls differentiation and development. 28th Annual Scientific Meeting, High Blood Pressure Research Council of Australia, (abstract published in Hypertension Volume 49, Number 6, pp. 1462-1481, June 2007), Brisbane, Australia (Plenary: Austin Doyle Lecture)
157. *Mattick JS (2006) The majority of the human genome is devoted to an RNA regulatory system that directs differentiation and development. Barcelona BioMed Conference on "RNAi: basic biology to clinical impact", Barcelona, Spain.
158. *Mattick JS (2007) The human genome as an RNA machine. Centenary Institute Colloquium: Opportunities in microRNA research. Sydney, Australia.
159. Webster RJ, Giles KM, Mattick JS and Leedman PJ (2007) MicroRNA regulation of growth factor receptor gene expression in human cancer. The 28th Lorne Genome Conference, Lorne, Australia.
John Mattick CV Page 37 160. *Mattick JS (2007) The majority of the mammalian genome is devoted to an RNA regulatory system that directs differentiation and development. The 28th Lorne Genome Conference, Lorne, Australia.
161. *Mattick JS (2007) The human genome as an RNA machine. 4th India-Australia Biotechnology Conference, Brisbane, Australia (Plenary).
162. Sunkin SM, Mercer TR, Dinger ME, Mehler MF, Jones AR and Mattick JS (2007) The noncoding RNA expression landscape in the mammalian brain. Cold Spring Harbor Laboratory Biology of the Genomes Conference, Cold Spring Harbor, USA.
163. *Mattick JS (2007) The human genome as an RNA machine. HGM'2007 (2007 Human Genome Meeting), Montreal, Canada.
164. Mercer TR, Dinger ME, Sunkin SM, Mehler MF and Mattick JS (2007) Precise expression patterns and subcellular localization of non-coding RNAs in mouse brain. IBRO World Congress of Neuroscience, Melbourne, Australia.
165. *Mattick JS (2007) Noncoding RNAs in differentiation and development. 6th Discovery Science and Biotechnology Meeting, Brisbane, Australia.
166. Pheasant M and *Mattick JS (2007) Much if not most of the human genome may be functional. SMBE'2007 (2007 Society of Molecular Biology and Evolution Meeting), Halifax, Canada.
167. *Mattick JS, Croft LJ, Dinger ME, Pheasant M, Makunin IV, Askarian Amiri M, Mercer TR, Pang KC, Simons C and Taft RJ (2007) The majority of the genomes of complex organisms encode regulatory RNAs that control differentiation and development. GSA'2007: 54th Annual Conference of the Genetics Society of Australasia, Sydney, Australia (Plenary).
168. *Mattick JS, Croft LJ, Dinger ME, Pheasant M, Makunin IV, Askarian-Amiri ME, Mercer TR, Pang KC, Simons C and Taft RJ (2007) The human genome as an RNA machine. FEBS'2007 (32nd FEBS Congress): Molecular Machines, Vienna, Austria.
169. *Mattick JS (2007) The majority of the genome of complex organisms is devoted to an RNA regulatory system that directs differentiation and development. ISCB/ECCB'2007: 15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) & 6th European Conference on Computational Biology (ECCB), Vienna, Austria (Keynote Plenary).
170. *Mattick JS (2007) The human genome as an RNA machine. MGED-10/AMATA-7 (joint meeting of the 10th Annual Microarray and Gene Expression Data Society and the 7th Annual Australian Microarray and Associated Technologies Association conference), Brisbane, Australia (Opening Plenary).
171. *Mattick JS (2007) The hidden layer of non-coding RNA in the evolution and genomic programming of complex organisms. 17th Annual Combined Biological Sciences Meeting, Perth, Australia (Opening Plenary).
172. *Mattick JS (2007) The human genome as an RNA machine. The 5th Colmar Symposium: “The New RNA Frontiers”, Colmar, France (Plenary).
173. Amaral PP, Dinger ME, Mercer TR, Bruce SJ, Askarian-Amiri M, Wilkins SJ, Neyt C, Soldà GME, Sunkin SM, Perkins AC and Mattick JS (2008) Characterization of long noncoding RNAs associated with developmental genes in vertebrates. The 29th Lorne Genome Conference, Lorne, Australia.
174. *Mattick JS (2008) The hidden layer of regulatory RNA in the development of complex organisms. Foundation des Treilles Meeting on "New catalytic and regulatory functions of RNA in eukaryotes," Nice, France (Plenary).
John Mattick CV Page 38 175. *Mattick JS (2008) The eukaryotic genome as an RNA machine. Genomes to Systems Conference, Manchester, UK (Plenary).
176. *Mattick JS (2008) The role of noncoding RNA in regulating gene expression in mammalian cells. Cell Culture Engineering XI, Coolum, Australia (Opening Plenary).
177. *Mattick JS (2008) The mammalian genome as an RNA machine. 2008 ASBMB (American Society for Biochemistry and Molecular Biology) Annual Meeting, San Diego, USA.
178. *Mattick JS (2008) The complexity and hidden layers of genetic information. Australian Genome Research Facility Tenth Anniversary Genomics Symposium, Melbourne, Australia (Plenary).
179. Nahkuri S, Taft RJ and Mattick JS (2008) Evolution of a snoRNA cluster by duplication. First International EURASNET Conference on Alternative Splicing: Abstract 63. Krakow, Poland.
180. Dinger ME, Mercer TR, Amaral PP, Pang KC, Sunkin SM, Mehler MF and Mattick JS (2008) Long noncoding RNAs in the central nervous system. Keystone Symposium: RNAi, MicroRNA, and Non- Coding RNA, Abstract #162. Whistler, Canada.
181. Pang KC, Dinger ME, Mercer TR, Amaral PP, Soldà GM, Bruce S, Gardiner G, Crowe ML, Perkins AC, Grimmond SM and Mattick JS (2008) Long noncoding RNAs in mouse embryonic stem cell differentiation. Keystone Symposium: RNAi, MicroRNA, and Non-Coding RNA, Abstract #355. Whistler, Canada.
182. Wilhelm D, Soldà GM, Dinger ME, Mercer TR, Simons C, Koopman P and Mattick JS (2008) Identification of a new class of non-coding RNAs associated with 3' untranslated regions. Keystone Symposium: RNAi, MicroRNA, and Non-Coding RNA, Abstract #472. Whistler, Canada.
183. Amaral PP, Dinger ME, Mercer TR, Pang KC, Askarian-Amiri M, Bruce SJ, Wilkins SJ, Neyt C, Soldà GM, Sunkin SM, Perkins AC and Mattick JS (2008) Characterization of long noncoding RNAs in mouse embryonic stem cell differentiation and vertebrate development. (P478, p. 319). XX International Congress of Genetics, Berlin, Germany.
184. Mercer TR, Dinger ME, Amaral PP and *Mattick JS (2008) RNA control of epigenetic processes. Queenstown Epigenetics Meeting, Queenstown, New Zealand.
185. Mercer TR, Dinger ME, Wilhelm D, Soldà G, Simons C, Glazov EA, Koopman P and *Mattick JS (2008) Regulated independent expression of 3' untranslated regions in mammals. Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
186. *Mattick JS (2008) The eukaryotic genome as an RNA machine. EMBO New Members Meeting, Tampere, Finland.
187. *Mattick JS (2008) The human genome as an RNA machine. European BioPerspectives, Hannover, Germany (Plenary).
188. *Mattick JS (2008) The human genome as an RNA machine. The 18th St Vincent's & Mater Health Research Symposium, Sydney, Australia (Opening Plenary).
189. *Mattick JS (2008) The human genome as an RNA machine. The RiGHT Symposium: RNA Interference Technology as Human Therapeutic Tool, Brussels, Belgium (Keynote Plenary).
190. *Mattick JS (2008) The genome is the transcriptome. The 8th Annual Australasian Microarray and Associated Technologies (AMATA) conference, Dunedin, New Zealand (Opening Plenary).
191. Mattick JS, Croft LJ, Pheasant M, Tim R Mercer TR and Dinger ME (2008) The mammalian genome as an RNA machine. FASEB Journal 22:397.3 [Meeting Abstract].
John Mattick CV Page 39 192. Jung C, Makunin IV and Mattick JS (2008) Bioinformatic analysis of conserved noncoding motifs: identification of two Drosophila-specific euchromatin-restricted sequences. Abstract 81, 4th EMBO Conference: From Functional Genomics to Systems Biology, Heidelberg, Germany.
193. *Mattick JS (2008) A new understanding of the human genome. 19th International Conference on Genome Informatics (GIW-2008), Gold Coast, Australia (Plenary).
194. Hansen MA, Jung C-H, Fernadez-Valverde S and Mattick JS (2008) Biopieces: a bioinformatics toolset and framework. 19th International Conference on Genome Informatics (GIW-2008), Gold Coast, Australia.
195. *Mattick JS (2009) A new understanding of the human genome. The Seventh Asia Pacific Bioinformatics Conference (APBC2009), Beijing, China (Plenary).
196. *Mattick JS (2009) The human genome as an RNA machine. Miami 2009 Winter Symposium: Interpreting the Human Genome. Miami, USA.
197. *Mattick JS (2009) The eukaryotic genome as an RNA machine: a new view of the evolution and genomic programming of complex organisms. Evolution - The Experience, Conference. Melbourne, Australia.
198. *Mattick JS (2009) The hidden layer of RNA in epigenetics, development and cell biology. The 2009 Lorne Genome Conference, Lorne, Australia (Plenary: Julian Wells Lecture).
199. *Mattick JS (2009) The hidden layer of RNA regulation in human development and cognition. The New World of RNAs, Biovision: 6th World Life Sciences Forum, Lyon, France.
200. *Mattick JS (2009) The role of RNA in the evolution, development and cognition of complex organisms. 2009 Cologne Spring Meeting: The Variable Genome, Cologne, Germany.
201. *Mattick JS (2009) The central role of RNA in the epigenetic control of differentiation and development. Mater Medical Research Institute 2009 Annual Stem Cell Symposium, Brisbane, Australia (Opening Plenary).
202. Amaral PP, Dinger ME, Mercer TR, Taft RJ and Mattick JS (2009) The RNA hypothesis for regulatory evolution in complex organisms. 74th Cold Spring Harbor Symposium on Quantitative Biology - Evolution: The Molecular Landscape, Cold Spring Harbor, New York, USA.
203. Mattick JS (2009) The eukaryotic genome as an RNA machine: a new view of the evolution and genomic programming of complex organisms. 74th Cold Spring Harbor Symposium on Quantitative Biology - Evolution: The Molecular Landscape, Cold Spring Harbor, New York, USA.
204. *Mattick JS (2009) The central role of RNA in evolution, development and cognition. Keystone Symposium: MicroRNA and Cancer, Abstract #005. Keystone, Colorado, USA. (Plenary).
205. *Mattick JS (2009) Conservatism, ideology and revolution in science. The Adelaide Festival of Ideas, Adelaide, Australia. (Plenary).
206. *Mattick JS (2009) RNA regulatory networks in brain function and disease. 4th European Society for Neurochemistry Conference on Advances in Molecular Mechanisms of Neurological Disorders, Leipzig, Germany (Plenary).
207. *Mattick JS (2009) The hidden layer of RNA regulation and RNA editing in brain. Wellcome Trust Conference on the Evolution of Brain, Behaviour & Intelligence, Hinxton, UK (Plenary).
208. *Mattick JS (2009) A new understanding of the human genome. Charles Darwin Symposium 2009 (Charles Darwin: Shaping our Science, Society and Future), Darwin, Australia (Plenary)
John Mattick CV Page 40 209. *Mattick JS (2009) The central role of RNA regulation in animal evolution, development and diversity. Comparative Genomics Workshop, 30th Anniversary Conference of the Association for the Advancement of Animal Breeding and Genetics (AAABG), Barossa Valley, Australia (Opening Plenary).
210. Dinger ME, Mercer TR and Mattick JS (2009) Beyond the exome: Re-interpretation of genome- wide association studies using an empirically-based annotation of the noncoding transcriptome. AMATA 2009 (9th Annual Australian Microarray and Associated Technologies Association) conference, Katoomba, Australia.
211. *Mattick JS, Taft RJ, Amaral PP, Nahkuri S, Mercer TR and Dinger ME (2009) RNA regulation of the epigenome. Epigenetics Annual Scientific Conference 2009, Melbourne, Australia (Plenary).
212. Askarian-Amiri ME, French JD, Dinger ME, Ru K, Smart CE, Brown MA and Mattick JS (2009) Characterization of a long noncoding RNA associated with mouse mammary gland development. Abstract #158, Epigenetics 2009, Melbourne, Australia.
213. Taft RJ, Amaral PP, Nahkuri S, Dinger ME, Mercer TR and *Mattick JS (2009) RNA regulation of the epigenome. Chromatin: Structure & Function Conference 2009, Costa Rica (Opening Plenary).
214. *Mattick JS (2010) RNA as the engine of complexity: a new view of human evolution and genomic programming. The Asiatic Society International Seminar on Darwin and Human Evolution, Kolkata, India (Plenary).
215. Dinger ME, Mercer TR and Mattick JS (2010) GWAS revisited: a new perspective on genome-wide association studies based on an empirical annotation of the coding and noncoding transcriptome. The 2010 Lorne Genome Conference, Lorne, Australia.
216. *Mattick JS (2010) The hidden layer of regulation of human development and brain function. Royal College of Pathologists of Australasia Pathology Update, Melbourne, Australia.
217. *Mattick JS (2010) RNA regulation of the epigenome. Epigenomics, Behaviour & Disease Symposium, Queensland Brain Institute, University of Queensland, Brisbane, Australia.
218. *Mattick JS (2010) RNA as the regulator of epigenetic memory and the mediator of epigenome- environment interactions. Keystone Symposium: Developmental Origins and Epigenesis in Human Health and Disease. Singapore (Plenary).
219. *Mattick JS (2010) Regulation of the epigenome. Mater Medical Research Institute Stem Cell Symposium 2010, Brisbane, Australia.
220. *Mattick JS (2010) The hidden layer of noncoding RNA in the epigenetic control of human development and cognition. European Society for Human Genetics, Gothenburg, Sweden.
221. *Mattick JS (2010) The central role of RNA in the evolution and ontogeny of developmentally complex and cognitively sophisticated organisms. ASBMB WA Branch Mundaring Weir Symposium, Fremantle, Australia (Plenary).
222. *Mattick JS (2010) The central role of RNA in the genetic programming of complex organisms. IRT 2010, Lyon, France (Opening Plenary).
223. *Mattick JS (2010) The central role of regulatory RNA in human evolution and development. 56th Brazilian Congress of Genetics, Guarujá, Brazil (Plenary).
224. *Mattick JS (2010) Challenging the dogma: the central role of RNA in the genomic programming of complex organisms. My1Bio Conference 2010, Kuala Lumpur, Malaysia (Plenary).
John Mattick CV Page 41 225. *Mattick JS (2010) The soft wiring underpinning human development and cognition. TRX10 Translational Research Excellence 2010), Brisbane, Australia (Opening Plenary).
226. *Mattick JS (2010) The expanding universe of regulatory RNA. 2010 Cold Spring Harbor Asia Conference on RNA Biology, Suzhou, China (Plenary).
227. *Mattick JS (2010) The expanding universe of regulatory RNA. RNAi Asia, Singapore, (Plenary).
228. *Mattick JS (2010) RNA regulation of epigenetic memory and epigenome-environment interactions. 2010 Australian Health and Medical Research Congress, Melbourne, Australia.
229. *Mattick JS (2010) RNA rules. 12th VCCRI International Symposium “Charting the depths of RNA: from molecules to therapies”, Sydney, Australia.
230. *Mattick JS (2010) Information and data challenges in biology. 6th IEEE International Conference on eScience, Brisbane, Australia (Plenary).
231. *Mattick JS (2010) RNA regulation of epigenetic processes. Howard Hughes Medical Institute Workshop “Unravelling Epigenomes in Health and Disease”, Washington, USA.
232. *Mattick JS (2011) RNA rules. EURASNET meeting on Alternative Splicing, Granada, Spain (Closing Plenary).
233. *Mattick JS (2011) RNA regulation of human development, cognition and disease. HGM 2011, Dubai, United Arab Emirates.
234. *Mattick JS (2011) Exploring the mammalian transcriptome. 2011 Illumina APAC Scientific Summit, Bali, Indonesia (Plenary).
235. Mattick JS (2011) RNA at the epicentre of human development and cognition. 7th Australasian Gene Therapy Society Meeting, Melbourne, Australia (Plenary).
236. Mattick JS (2011) The hidden layer of RNA regulation in animal evolution and development. 7th Advances in Reproductive Biology and Genetics, Columbia, Missouri, USA (Plenary)
237. *Mattick JS (2011) Challenging the dogma: the central role of RNA in human development and cognition. FEBS 2011, Turin, Italy (Plenary: IUBMB Lecture PL.6, FEBS Journal 278 (Suppl.1): 2 (2011).
238. Khaitan D, Dinger ME, Mazar J, Crawford J, Smith MA, Mattick JS and Perera R (2011) The melanoma-upregulated long noncoding RNA SPRY4-IN1 modulates apoptosis and invasion. FEBS 2011, Turin, Italy (Symposium talk S2.1.6, Poster P02.14) FEBS Journal 278 (Suppl.1): 88 (2011).
239. *Mattick JS (2011) Genetic information and the data avalanche in biology. QUESTnet 2011, Gold Coast, Australia (Keynote Plenary).
240. *Mattick JS (2011) The central role of RNA in human development. AIMS / NZIMLS SPC 2011 (Australian Institute of Medical Scientists / New Zealand Institute of Medical Laboratory Science South Pacific Congress 2011), Gold Coast, Australia (Opening Plenary).
241. *Mattick JS (2011) RNA control of epigenetic processes. International Meeting on Chromatin Changes in Differentiation and Malignancies, Giessen, Germany (Plenary).
242. *Mattick JS (2011) RNA rules. Wellcome Trust Conference on Epigenomics of Common Diseases, Hinxton, UK (Plenary).
243. *Mattick JS (2011) RNA at the epicentre of development and cognition. Theo Murphy International Scientific Meeting on Non-protein-coding RNAs - the DNA–RNA dialogue in shaping the transcriptome. Royal Society Kavli Hall, Chicheley, UK (Plenary).
John Mattick CV Page 42 244. *Mattick JS (2011) The hidden layer of RNA regulation underpinning human development and cognition. The 14th SSBP (Society for the Study of Behavioural Phenotypes) International Research Symposium, Brisbane, Australia (Opening Plenary).
245. *Mattick JS (2011) RNA regulation – challenging the dogma. AACB50 (49th Annual Meeting of the Australasian Association of Clinical Biochemists). Sydney, Australia (Opening Plenary: David Curnow Plenary Lecture).
246. *Mattick JS (2011) The multifunctional nature of RNA and the hidden human proteome. The 9th Australian Peptide Conference, Hamilton Island, Australia (Opening Plenary).
247. *Mattick JS (2011) RNA signaling in cell and developmental biology. The 5th Barossa Meeting on Cell Signaling and Molecular Medicine, Barossa Valley, Australia.
248. *Mattick JS (2012) The genomic revolution and the genomic programming of human development. The Royal Australasian College of Physicians Annual Congress, Brisbane, Australia (Opening Plenary: Arthur E Mills Oration).
249. *Mattick JS (2012) The extraordinary precision of chromatin architecture and transcription. Epigenetics 2012, Adelaide, Australia.
250. *Mattick JS (2012) Long noncoding RNAs in human evolution, development and cognition. Keystone Symposium: Non-Coding RNAs. Snowbird, Utah, USA (Plenary; Co-organizer).
251. *Mattick JS (2012) RNA at the epicentre of human evolution, development and cognition. XLI Annual Meeting of the Brazilian Biochemistry and Molecular Society (SBBq), Foz do Iguaçu, Brazil (Opening Plenary).
252. *Mattick JS (2012) RNA at the epicentre of human development. INSERM Atelier de Formation 215: Diversity of the non-coding transcriptome revealed by RNAseq, Bordeaux, France (Opening Plenary).
253. *Mattick JS (2012) The extraordinary depth and complexity of the human transcriptome. Non- coding Genome, Institut Curie, Paris, France (Opening Plenary).
254. *Mattick JS (2012) The hidden layer of RNA-mediated epigenetic regulation in human development. 2012 SGI (Society for Gynaecological Investigation) Summit, "Prematurity and Stillbirth: Antecedents, Mechanisms and Sequelae”, Brisbane, Australia (Plenary).
255. *Mattick JS (2012) Strategic planning of the research portfolio with community engagement. Philanthropy in Health and Medical Research Conference 2012, Melbourne, Australia (Plenary).
256. *Mattick JS (2012) RNA at the epicentre of human development. QMB Non-coding RNA, Queenstown, New Zealand (Plenary).
257. *Mattick JS, Mariasegaram M, Dinger ME, Poronnik P, Nikolic-Paterson D and Greg Tesch G (2012) The epigenetic control of human development and disease: characterization of long noncoding RNAs in a mouse model of diabetic nephropathy. International Society of Nephrology Forefronts Symposium on ‘Tubulointerstitial Disease in Diabetic Nephropathy’, Melbourne, Australia.
258. *Mattick JS (2012) The hidden layer of RNA-mediated epigenetic regulation in human development and disease. Sydney Cancer Conference, Sydney, Australia (Plenary).
259. *Mattick JS (2012) RNA at the epicentre of human development. Frontiers in Cancer Science, Singapore (Plenary).
260. *Mattick JS (2012) The impact of genomics on biology and medicine. Endocrinology and Diabetes Forum: Advances and Future Directions, Sydney, Australia (Opening Plenary).
John Mattick CV Page 43 261. *Mattick JS (2012) The central role of RNA in human development and cognition. 2012 Merck Millipore Asia Bioforums, Singapore, Ghuangzhou and Taipei (Opening Plenaries).
262. *Mattick JS (2012) Challenging the dogma: the central role of RNA in the evolution and development of complex organisms. Biology 2012 and Beyond, 25th Anniversary Symposium, CSIR Centre for Cellular and Molecular Biology, Hyderabad, India (Plenary).
263. *Mattick JS (2012) The impact of genomics on medicine and healthcare. Private Healthcare Australia Conference 2012, Melbourne, Australia (Plenary).
264. *Mattick JS (2012) Transcriptome profiling; the most accurate and sensitive marker of cell state? 2nd Biomarker Discovery Conference, Shoal Bay, Australia (Plenary).
265. *Mattick JS (2013) The role of regulatory RNA in human development and disease. Keystone Symposium: Noncoding RNAs in Development and Cancer. Vancouver, Canada (Plenary).
266. *Mattick JS (2013) The role of regulatory RNA in human development and disease. Wellcome Trust Conference on Genomic Disorders, Cambridge, UK (Plenary).
267. *Mattick JS (2013) Long noncoding RNAs in human development and disease. Human Genome Meeting 2013 and 21st International Congress of Genetics, Singapore.
268. *Mattick JS (2013) The human genome as the zip file extraordinaire. Australian Society for Medical Research (ASMR) NSW Annual Scientific Meeting, Sydney, Australia (Plenary).
269. *Mattick JS (2013) The hidden layer of regulatory RNA in human development. 4th International NanoMedicine Conference, Sydney, Australia (Plenary).
270. *Mattick JS (2013) The hidden layer of RNA regulation of human development and physiology. NSW Endocrine/Renal Scientific Meeting, Sydney, Australia.
271. *Mattick JS (2013) The human genome as the zip file extraordinaire. Genetics Society of Australia 2013 Annual Conference, Sydney, Australia (Plenary).
272. *Mattick JS (2013) RNA at the epicentre of human evolution, development and cognition. IUPS2013 (International Union of Physiological Societies), Birmingham, UK.
273. *Mattick JS (2013) Challenging the dogma: a new view of the genomic programming of human development. American Association for Clinical Chemistry Annual Meeting, Houston, USA (Plenary).
274. *Mattick JS (2013) The hidden layer of RNA regulation in human development. Australian Centre for Perinatal Science Inaugural Conference, Sydney, Australia (Plenary).
275. *Mattick JS (2013) The hidden layer of RNA regulation in human development. 2013 Riboclub Meeting, Quebec, Canada (Opening Plenary).
276. *Mattick JS, Mercer TR, Clark MB and Dinger ME (2013) The human genome as the zip file extraordinaire. The 14th International Meeting on Human Genome Variation and Complex Genome Analysis (HGV2013), Seoul, Korea (Plenary).
277. *Mattick JS (2013) The hidden layer of RNA regulation in human development. Nobel Symposium: Regulatory RNAs in Development, Disease and Evolution, Karolinska Institute, Stockholm, Sweden (Plenary).
278. *Mattick JS, Mercer TR, Clark MB and Dinger ME (2013) The human genome as the zip file extraordinaire. EMBO∣EMBL Symposium: The Non-Coding Genome, Heidelberg, Germany (Plenary).
John Mattick CV Page 44 279. *Mattick JS (2013) The hidden layer of regulatory RNA in human development and disease, 1st Malaysian National Conference for Cancer Research and 5th Regional Conference on Molecular Medicine, Kuala Lumpur, Malaysia (Plenary).
280. *Mattick JS (2014) The central role of RNA in cognitive function, 11th Annual World Congress of the Society for Brain Mapping & Therapeutics (SBMT), Sydney, Australia (Plenary).
281. *Mattick JS (2013) RNA at the epicentre of human development, Society for Toxicology 53rd Annual Meeting, Phoenix, USA (Plenary).
282. *Mattick JS (2014) RNA at the epicenter of human development. Non-coding RNA: From basic mechanisms to cancer, DKFZ, Heidelberg, Germany (Keynote Lecture).
283. *Mattick JS (2014) RNA at the epicenter of human development. 1st PSB Blue Symposium, EMBL Grenoble, France (Keynote Lecture).
284. *Mattick JS (2014) RNA at the epicenter of human evolution, development and cognition. DNA Habitat and its RNA Inhabitants, Salzburg, Austria (Keynote Lecture).
285. *Mattick JS (2014) The impact of genomics on medicine and healthcare. 13th Annual Health Insurance Summit, Sydney, Australia (Plenary).
286. *Mattick JS (2014) RNA at the epicentre of human development. InCoB (International Conference on Bioinformatics), Sydney, Australia (Plenary).
287. *Mattick JS (2014) Development and implementation of clinical genomics. 38th Annual Scientific Meeting, Human Genetics Society of Australasia, Adelaide, Australia (Plenary 3).
288. *Mattick JS (2014) Identification of new RNA genes in GWAS regions associated with complex diseases. 38th Annual Scientific Meeting, Human Genetics Society of Australasia, Adelaide, Australia (Plenary 6).
289. *Mattick JS (2014) The massive hidden layer of RNA regulation in complex organisms. The 15th International Conference on Systems Biology (ICSB), Melbourne, Australia (Plenary).
290. *Mattick JS (2014) The central importance of genomics to medical research and health economics. The Conversation: The Future of Medical Research, Sydney, Australia (Plenary).
291. *Mattick JS (2014) The central role of regulatory RNA in human development and disease. MD Anderson Cancer Center Symposia on Cancer Research: Illuminating dark matter – ncRNA in disease and cancer. Houston, USA (Plenary – Bertner Award Lecture).
292. *Mattick JS (2014) The human genome as the zip file extraordinaire. AGTA (Australasian Genomic Technologies Association), Melbourne, Australia (Opening Plenary).
293. *Mattick JS (2014) RNA signalling. 7th Garvan Signalling Symposium, Sydney, Australia.
294. *Mattick JS (2014) Neuroscience: the last casualty of the protein-centric zeitgeist of molecular biology. Brain Sciences UNSW Symposium – Brain Health Complexity: From Molecules to Systems, University of New South Wales, Sydney, Australia.
295. *Mattick JS (2014) RNA at the epicentre of human development. Inaugural Joint Meeting of the Australian and Japanese RNA Societies, Sydney, Australia (Opening Plenary).
296. *Mattick JS (2014) The transformational impact of genomics on science and medicine. International Proteostasis & Disease Syposium 2014, Wollongong, Australia.
297. *Mattick JS (2014) The impact of genomics on research and medicine. 2014 Laboratory Management Conference, Sydney, Australia (Opening Keynote Lecture).
John Mattick CV Page 45 298. *Mattick JS (2014) The impact of genomics on research and medicine. Informa Conference on Genomics in Healthcare, Sydney, Australia (Keynote Address).
299. *Mattick JS (2014) Transforming the diagnosis, understanding and treatment of paediatric disease through genomics. UNSW Paediatric Research Showcase, Sydney, Australia (Keynote Address).
300. *Mattick JS (2014) New and emerging technologies in genomics. The Future of Research Conference, Sydney, Australia.
301. *Mattick JS (2014) The challenge of innovation for Austrlia in a dynamic Asian context. Strategic Management Society 2014 Special Conference, Sydney, Australia.
302. *Mattick JS (2015) RNA at the epicentre of human development. Functions of Noncoding RNAs in Evolution, Epigenetics and Therapeutic Applications. Genome Institute of Singapore (Opening Keynote Lecture).
303. *Mattick JS (2015) The human genome as the zip file extraordinaire. Keystone Symposium: Long Noncoding RNAs - From Evolution to Function. Keystone, Colorado, USA.
304. *Mattick JS (2015) The misunderstanding of molecular biology. Science on the Swan: Hot Topics in Life Course and Development. Perth, Australia (Plenary).
305. *Mattick JS (2015) The hidden layer of RNA regulation in human genetic programming. Australian and New Zealand Microcirculation Society Annual Meeting. Leura, NSW, Australia (Opening Keynote Lecture).
306. *Mattick JS (2015) The genome generation. International Summit on Population and Medical Genomics, St Andrews, Scotland, UK (Plenary).
307. *Mattick JS (2015) Medical research and the PHI industry. Informa 14th Annual Health Insurance Summit, Sydney, Australia.
308. *Mattick JS (2015) The transformation of medicine and the Lions Kids Cancer Genome Project. Lions International 2015 ANZI Pacific Forum, Auckland, New Zealand (Keynote Lecture).
309. *Mattick JS (2015) RNA at the centre: the nature and scaling of the molecular processes controlling autopoiesis in complex organisms. Royal Society Theo Murphy Meeting on Long Noncoding RNAs: evolution of new epigenetic and post-transcriptional functions. Milton Keynes, England (Plenary Lecture).
310. *Mattick JS (2015) The central role of regulatory RNA in human development and brain function. 2nd International Conference on FMR1 premutation: basic mechanisms ans clinical involvement, Sitges, Barcelona, Spain (Plenary Lecture).
311. *Mattick JS (2015) The genome generation. SAHMRI Scientific Symposium on Big Data, Adelaide, Australia (Plenary Lecture).
312. *Mattick JS (2015) The extraordinary complexity of the human coding and noncoding transcriptome. 11th International Conference of the Brazilian Association of Bioinformatics and Computational Biology, Sao Paulo, Brazil (Opening Keynote Lecture).
313. *Mattick JS (2015) The hidden layer of regulatory RNA in mammalian genome biology. 29th Annual Conference of the International Mammalian Genome Society, Yokohama, Japan (Plenary: Verne M. Chapman Lecture).
314. *Mattick JS (2015) The central role of regulatory RNA in chromatin organization and epigenetic memory. International Human Epigenome Consortium Annual Meeting, Tokyo, Japan (Plenary Lecture).
John Mattick CV Page 46 315. *Mattick JS (2015) The transformation of biology and medicine through genome sequencing. ELEVATE, Illumina APAC Regional Meeting, Siem Riep, Cambodia (Plenary Lecture).
316. *Mattick JS, Deveson D, Hardwick S, Bartonicek N, Dinger ME, Mercer TR (2016) The extraordinary depth and complexity of the human transcriptome. The 13th International Congress of Human Genetics, Kyoto, Japan.
317. *Mattick JS (2016) The central role of RNA in human development, cognition and adaptation. 6th International Conference on The Science of Nutrition in Medicine and Healthcare, Sydney, Australia (Closing Plenary Lecture).
318. *Mattick JS (2016) RNA structure meets function. EMBO Workshop, Stockholm, Sweden (Opening Keynote Lecture).
319. *Mattick JS (2016) The hidden layer of regulatory RNA in human development and cognition. 31st Congress of the International Society for the Advancement of Cytology, Seattle, USA (Keynote Lecture).
320. Borcz A, Buckley MF, Budd P, Burnett L, Constantinescue L, Copty J, Cowley M, Dinger ME, Ewans L, Gonzalez M, Groza T, Kaplan W, Lubka-Pathak M, Lundie B, Mattick JS, Mead S, Miller D, Morris P, Pinese M, Roscioli T, Saroufim D, Statham A, Stockmyer J, Ying K (2016) Accrediting Australasia's first clinical whole genome sequening (WGS) service. HGSA 40th Annual Scientific meeting, Hobart, Australia.
321. *Mattick JS (2016) The revolutionary impact of genomics on medicine and healthcare. 25th Annual Brisbane and Women's Hospital Symposium, Brisbane, Australia.
322. *Mattick JS (2016) Understanding ourselves: genomics and machine learning. Humans, Machines, and the Quest for Better Mental Health Conference, University of New South Wales, Sydney, Australia.
323. *Mattick JS (2016) Regulatory RNA: the epicentre of vertebrate evolution and development. The 9th Zebrafish Disease Models Society, Singapore (Keynote Lecture).
324. *Mattick JS (2016) Biomedical discovery in warp drive: the integration of genomic data, clinical records, the internet of things and machine learning. eResearch Australasia Conferene 2016, Melbourne (Plenary Lecture).
325. *Mattick JS (2016) RNA at the epicentre of human development and cognition. International Fellows Symposium on Neurogenomics. Garvan Institute of Medical Research, Sydney.
326. *Mattick JS (2016) The genomic programming of human development and cognition, and the coming revolution in medical research and healthcare. Third EMBL Postgraduate Symposium, South Australian Health & Medical Research Institute, Adelaide, Australia (Plenary Lecture).
LECTURES / RESEARCH SEMINARS
1. The new genetics and the story of life. The Queensland Museum, 1991.
2. The scientific and commercial implications of genome projects and genome analysis. The 10th Australian Biotechnology Conference, Melbourne, February 1992.
3. The significance of genome research. International Genome Science Meeting, Adelaide, February 1992.
4. Microbial genomes. International Genome Science Meeting, Adelaide, February 1992.
John Mattick CV Page 47 5. The new genetics and zoological conservation. The Second Joint ARAZPA/ASZK Annual Zoological Conference, Currumbin Sanctuary, April 1992.
6. Genome analysis - a paradigm shift in biological research. The Campus Genetics Society, University of New South Wales, April 1992.
7. The new genetics and the story of life. The 1992 Butler Memorial Lecture, University of Queensland, September 1992.
8. A genome approach to exploring biological systems. Fairfield Hospital, Melbourne, July 1993.
9. The molecular genetics of type 4 fimbriae in bacterial pathogens. Department of Genetics, Cambridge University, Cambridge, September 1993.
10. The Gene Library. Department of Biochemistry and Molecular Biology, UMIST, Manchester, October 1993.
11. Does one gene equal one protein? Department of Genetics, Cambridge University, Cambridge, March 1994.
12. Does one gene equal one protein: the significance of introns and RNA-based gene regulation in eukaryotic evolution. Adelaide Children’s Hospital, Adelaide, June 1994
13. Does one gene equal one protein: the significance of introns and RNA-based gene regulation in eukaryotic evolution. Childrens Medical Research Institute, Sydney, June 1994.
14. Does one gene equal one protein: the significance of introns and RNA-based gene regulation in eukaryotic evolution. Department of Biochemistry, University of Queensland, Brisbane, August 1994.
15. Does one gene equal one protein: the significance of introns and RNA-based gene regulation in eukaryotic evolution. Queensland Institute for Medical Research, Brisbane, August 1994.
16. The new genetics? Genetic Futures: the scientific, ethical, social, religious and environmental implications of genetic technology. Conference held by The Australian Institute of Ethics and the Professions at St Johns College, the University of Queensland, September 1994.
17. Biogenesis of type 4 fimbriae in Pseudomonas aeruginosa and related pathogens. Department of Microbiology and Immunology, The University of Adelaide, Adelaide, October 1994
18. Graduation Address The University of New South Wales Faculties of Science and Medicine, Sydney, October 1994.
19. Does one gene equal one protein: the role of introns in eukaryotic development. The John Curtin School of Medical Research, Australian National University, Canberra, October 1994.
20. The 1995 Colliver Lecture: The new genetics - implications for our future. The Queensland Museum, Brisbane, June 1995.
21. The biogenesis, function and regulation of type 4 fimbriae, and their relationship to other virulence factors in Pseudomonas aeruginosa. Institute of Molecular Medicine, University of Oxford, Oxford, November 1995.
22. The importance of genome research to medicine. Australian Medical Students Association 1996 Meeting, Brisbane, June 1996.
23. RNA signalling and processing in mammalian development. The Institute for Reproduction and Development, Monash Medical Centre, July 1996.
John Mattick CV Page 48 24. The impact of molecular genetics on the future of chemistry. 14th International Conference on Chemical Education, Brisbane, July 1996.
25. RNA signalling and processing in mammalian development. Johnson and Johnson Research Centre, Sydney, August 1996.
26. Genomes and development. Faculty of Science, Queensland University of Technology, Brisbane, September 1996.
27. The Australian Genome Research Facility. Peter MacCallum Institute for Cancer Research, Melbourne, September 1996.
28. The Australian Genome Research Facility. Genetics, Cancer and Cardiovascular Disease Conference, Lorne, September 1996.
29. The human genome project. Royal Society of Queensland Special Symposium on Exploring our genes and genetic heritage, Brisbane, October 1996
30. Understanding the human genome. XIIIth Annual Royal North Shore Hospital/ University of Technology Sydney Scientific Research Meeting, Sydney, November 1996.
31. The impact of genome projects on medical research and the future of medicine. AWT Edwards Oration at the 35th National Scientific Conference of the Australian Society for Medical Research, Gold Coast, November 1996.
32. The information age in biotechnology. The Licensed Executives Society (Australia and New Zealand), Brisbane, March 1997.
33. Butland Visiting Professor Oration: The human genome project and the future of medicine. University of Auckland, Auckland, August 1997.
34. RNA-mediated gene regulation in mammalian development. Faculty of Health Sciences, University of Auckland, Auckland, August 1997.
35. Type 4 fimbriae. Faculty of Health Sciences, University of Auckland, Auckland, August 1997.
36. The human genome project and the changing face of biology. CONSTAQ ‘97 (1997 Conference of the Science Teachers Association of Queensland), Brisbane, August 1997.
37. The human genome project and the future of biology. The Leo Howard Vacation School, University of Queensland, Brisbane, January 1998.
38. The impact of genomics on the future of biology and medicine. Human Genome Research - Science and Society. The Garvan Institute of Medical Research, Sydney, April 1998.
39. Genomics and biotechnology. NZ Medical Research Council Foresight Meeting, Auckland, June 1998.
40. Genomics in Australia. Bioinformatics Conference, Australian Academy of Science, Canberra, July 1998.
41. The Institute of Molecular Bioscience. University of Queensland Customs House, Brisbane, November 1998.
42. Genomics. 9th Wheat Breeding Assembly, Toowoomba, September 1999.
43. The impact of genomics on the future of medicine. Australian College of Legal Medicine, Canberra, October 1999.
John Mattick CV Page 49 44. Novel therapies for the new millenium. Leukaemia Foundation Annual Conference, QIMR, Brisbane, October, 1999.
45. Genomics. Biofutures Conference, The Brisbane Institute, Brisbane, October 1999.
46. Host colonisation by Pseudomonas aeruginosa – complex signal transduction pathways which integrate multiple virulence factors and colonial behaviour. Children’s Medical Research Institute, Westmead, Sydney, October 1999.
47. The end of reductionist biology. The Queensland Protein Group, Brisbane, November 1999.
48. Twitching motility in bacteria. Department of Plant Sciences, The University of Oxford UK, May 2000.
49. The molecular genetics of type IV pili and host colonisation in Pseudomonas aeruginosa. Department of Cell and Molecular Biology, Umeå University, Umeå Sweden, June 2000.
50. The role of introns and RNA-based gene regulation in eukaryotic evolution and development. Department of Human Anatomy and Genetics, The University of Oxford UK, June 2000.
51. The development of the Institute for Molecular Biosciences and the future of biology as an information science. School of Biomedical Sciences, University of Ulster, Coleraine UK, June 2000.
52. The molecular genetics of type IV fimbriae and host colonisation in Pseudomonas aeruginosa and construction of an interactive web-based genome database. Department of Microbiology and Immunobiology, Queens University, Belfast UK, June 2000.
53. The implications of the human genome project for medicine, healthcare and humanity in the 21st century. The Kuringai District Medical Association and South African Medical Association, Sun City, South Africa, July 2000.
54. Striking the balance in Australia: “A Code of Ethical Practice for Biotechnology” Australian Biotechnology Event, World Expo 2000, Hannover, Germany, July 2000.
55. Biomedical, Biotechnology and Pharmaceutical Innovation: Australia's Opportunities. Australian Biotechnology Event, World Expo 2000, Hannover, Germany, July 2000.
56. The role of introns and RNA-based gene regulation in eukaryotic evolution and development. EMBL (European Molecular Biology Laboratory), Heidelberg, Germany, July 2000.
57. The molecular genetics of type IV fimbriae and host colonisation in Pseudomonas aeruginosa and construction of an interactive web-based genome database. Department of Medical Microbiology, St Bartholomew's and the Royal London School of Medicine and Dentistry, London, UK, July 2000.
58. The molecular genetics of type IV fimbriae and host colonisation in Pseudomonas aeruginosa and construction of an interactive web-based genome database. Lehrstuhl Biologie der Mikroorganismen, Ruhr-Universitaet Bochum, Bochum, Germany, September 2000.
59. The molecular genetics of type IV fimbriae and host colonisation in Pseudomonas aeruginosa and construction of an interactive web-based genome database. Institute for Molecular Medicine, Oxford, UK, September 2000.
60. The evolution of controlled multitasked networks: a role for introns and other noncoding RNAs. CNRS Marseille, France, September 2000.
61. The molecular genetics and genomics of Pseudomonas aeruginosa host colonisation and pathogenesis. Austin Research Institute, Melbourne, November 2000.
John Mattick CV Page 50 62. The modern RNA world: tips of an iceberg. Ludwig Institute for Cancer Research, Melbourne, November 2000.
63. Non-human genome sequences (pathogens and vectors). WHO Multi-regional Meeting on Genomics and Health, Bangkok, Thailand, July 2001.
64. The role of introns and other noncoding RNAs in eukaryotic evolution and development. Walter and Eliza Hall Institute of Medical Research, Melbourne, August 2001.
65. Relationships between Research, Health and the Economy. Queensland Health Research and Development Forum, Brisbane, August 2001.
66. RNA-based gene regulation in evolution and development. Victor Chang Cardiac Research Institute, Sydney, October 2001.
67. The genomics juggernaut: is government keeping pace with science? Australian Medical Writers Association (AMWA) Conference, Brisbane, November 2001.
68. Life from a genomic perspective. Department of Biochemistry and Molecular Biology, Australian National University, Canberra, November 2001.
69. The role of noncoding RNAs in eukaryotic evolution and development. Department of Biochemistry, University of Western Australia, Perth, March 2002.
70. The Human Genome Project – understanding ourselves. Institute of Advanced Studies, University of Western Australia, Perth, March 2002.
71. Introns and noncoding RNAs – the hidden layer of biological complexity. School of Medical Sciences, University of Queensland, Brisbane, August 2002.
72. The genetic basis of human complexity and variation. St. Vincent’s Institute of Medical Research, Melbourne, August 2002.
73. Exciting new perspectives on the role of junk DNA as a regulator of gene expression. Murdoch Childrens Research Institute, Melbourne, August 2002.
74. An elephant is not like E. coli: the role of introns and other noncoding RNAs in the evolution and development of complex organisms. Kölling Institute of Medical Research, Sydney, September 2002.
75. The new genetics and biochemistry: noncoding RNA transactions in eukaryotic differentiation and development. Institute for Biochemistry, University of Köln, Köln, Germany, October 2002.
76. An elephant is not like E. coli: the role of introns and noncoding RNAs in eukaryotic evolution and development. School of Life Sciences, University of Dundee, Dundee, Scotland, November 2002.
77. The role of introns and noncoding RNAs in eukaryotic evolution and development. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, November 2002.
78. An elephant is not like E. coli: the role of introns and noncoding RNAs in eukaryotic evolution and development. Institute for Molecular and Medical Biology, Université Libre de Bruxelles, Brussels, Belgium, November 2002.
79. The hidden layer of eukaryotic complexity: introns and noncoding RNAs in eukaryotic evolution and development. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland, December 2002.
John Mattick CV Page 51 80. An elephant is not like E. coli: the role of introns and noncoding RNAs in eukaryotic evolution and development. Institute for Technical Biochemistry, University of Stuttgart, Stuttgart, Germany, December 2002.
81. An elephant is not like E. coli: the role of introns and noncoding RNAs in eukaryotic evolution and development. Institute of Experimental Pathology, University of Münster, Münster, Germany, January 2003.
82. The hidden layer of eukaryotic complexity: introns and noncoding RNAs in eukaryotic evolution and development. European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, January 2003.
83. An elephant is not like E. coli: the role of introns and noncoding RNAs in eukaryotic evolution and development. University of Liége, Liége, Belgium, January 2003.
84. The programming of complex organisms: the hidden layer of noncoding RNA. Australia-Japan Biomedical Sciences Symposium, Melbourne, February 2003.
85. The programming of complex organisms: the hidden layer of noncoding RNA. Genetics Society (Inaugural Lecture), National University of Ireland, Cork, Ireland, March 2003.
86. The programming of complex organisms: the hidden layer of noncoding RNA. Department of Evolutionary Biology, University of Copenhagen, Copenhagen, Denmark, March 2003.
87. The programming of complex organisms: the hidden layer of noncoding RNA. Department of Physics, University of Queensland, Brisbane, March 2003.
88. The programming of complex organisms: the hidden layer of noncoding RNA. School of Molecular and Microbial Sciences, University of Queensland, Brisbane, March 2003.
89. Graduation Address. The University of Southern Queensland, Toowoomba, April 2003.
90. The autopoietic programming of complex organisms: the hidden layer of noncoding RNA. Karolinska Institute, Stockholm, Sweden, June 2003.
91. The autopoietic programming of complex organisms: the hidden layer of noncoding RNA. National Cancer Institute, NIH, Bethesda, USA, June 2003.
92. Programming the autopoietic development of complex organisms: the hidden layer of non-coding RNA. The Complex Systems Seminar Series, University of Queensland, Brisbane, August 2003.
93. The genetic programming of human development: the hidden layer of noncoding RNA. Westmead Hospital Research Symposium (Plenary Speaker), Sydney, August 2003.
94. The genomic programming of complex organisms. RIKEN Genome Sciences Center, Yokohama, Japan, August 2003.
95. The human genome project. EINSHAC – Australian Genetics in the Courtroom, Sydney, September 2003.
96. Genomic programming of complex organisms: the hidden layer of noncoding RNA. Affymetrix Inc., Santa Clara CA, USA, November 2003.
97. Genomic programming of complex organisms: the hidden layer of noncoding RNA. California Institute of Technology, Pasadena CA, USA, November 2003.
98. Convocation Address, Emmanuel college, University of Queensland, Brisbane February 2004.
99. The human genome project: science, medicine and ethics. Chartered Accountants Business Forum (Qld) 2004, Sanctuary Cove, March 2004.
John Mattick CV Page 52 100. The programming of complex organisms: the hidden layer of noncoding RNA. Invited meeting on ncRNA in regulation and evolution – Testing the hypothesis of ncRNA based regulatory networks, University of Copenhagen, March 2004.
101. The programming of complex organisms: the hidden layer of noncoding RNA. RIKEN Genome Sciences Center, Yokohama, Japan, July 2004.
102. The digital programming of eukaryotic complexity and variation by noncoding RNA. John Curtin School of Medical Research, Australian National University, Canberra, September 2004.
103. The genomic programming of complex organisms: the hidden layer of noncoding RNA. Purdue University, West Lafayette, Indiana, USA, September 2004.
104. Genomic programming of human development. Fourth Annual Baker Heart Research Institute and The George Institute for International Health Symposium, Noosa, October 2004.
105. Human genomic programming: the hidden layer of noncoding RNA. Hunter Medical Research Institute, University of Newcastle, Newcastle, February 2005.
106. The hidden layer of digital RNA programming in complex organisms. Départment de Biologie du Développement, Institut Pasteur, Paris, March 2005.
107. The role of noncoding RNA in the evolution and development of complex organisms. University of Waikato, Hamilton, New Zealand, April 2005.
108. The hidden layer of noncoding RNA in the genetic programming of complex organisms. The Hanson Institute, Adelaide, April 2005.
109. The hidden layer of noncoding RNA in the digital programming of complex organisms. EMBO Symposium in Molecular Medicine, University of Uppsala, Sweden, June 2005.
110. International Research in Science at Technology at the University of Queensland. Indooroopilly State High School, July 2005.
111. Noncoding RNA: the hidden layer of genetic programming in complex organisms. 7th Melbourne Bioinformatics Course, Howard Florey Institute of Experimental Physiology and Medicine, July 2005.
112. The hidden layer of noncoding RNA in the evolution and development of complex organisms. Institute for Systems Biology, Seattle, Washington, USA, September 2005.
113. The hidden layer of noncoding RNA in the evolution and development of complex organisms. Fred Hutchinson Cancer Research Center, Seattle, Washington, USA, September 2005.
114. The hidden layer of noncoding RNA in human genetic programming. Human Genetics Society of Australasia (Queensland Branch) seminar, Royal Children's Hospital, Brisbane, January 2006.
115. The hidden layer of noncoding RNA regulatory networks in the evolution and development of complex organisms. Max-Planck-Institut für Infektionsbiologie, Berlin, Germany, March 2006.
116. The hidden layer of noncoding RNA regulatory networks in the evolution and development of complex organisms. Centre de Regulació Genòmica, Barcelona, Spain, March 2006.
117. The hidden layer of noncoding RNA regulatory networks in the evolution and developmental programming of complex organisms. Liverpool Centre for BioComplexity and Faculty of Biological Sciences, University of Liverpool, United Kingdom, March 2006.
118. The secrets of our genes. Brisscience, Brisbane, March 2006.
John Mattick CV Page 53 119. The role of noncoding RNA in human development. Centre for Immunology and Cancer Research, Princess Alexandra Hospital, Brisbane, March 2006.
120. The hidden layer of noncoding RNA in the evolution and developmental programming of complex organisms. Centre for Biotechnology Colloquium, University of Bielefeld, Bielefeld, Germany April 2006.
121. The hidden layer of noncoding RNA in the genomic programming of human differentiation and development. Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Canada, May 2006.
122. The hidden layer of non-coding RNA in the evolution and development of complex organisms. Innovator Series Lecture: IBM TJ Watson Research Laboratories, New York, USA, May 2006.
123. The hidden layer of non-coding RNA in the evolution and development of complex organisms. Department of Control & Dynamical Systems, Electrical Engineering, and BioEngineering, California Institute of Technology, Pasadena CA, USA, June 2006.
124. The hidden layer of non-coding RNA in the evolution and development of complex organisms. EMBO Symposium in Molecular Medicine, University of Uppsala, Sweden, June 2006.
125. The majority of the genome in complex organisms encodes an RNA regulatory system. Department of Genetics, University of Melbourne, Melbourne, August 2006.
126. Noncoding RNA. 8th Melbourne Bioinformatics Course, Howard Florey Institute of Experimental Physiology and Medicine, Melbourne, September 2006.
127. The majority of the human genome encodes a hidden RNA regulatory system that controls differentiation and development. Academic Medical Center, University of Amsterdam, The Netherlands, September 2006.
128. The majority of the human genome encodes a hidden RNA regulatory system that controls differentiation and development. The Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht, The Netherlands, September 2006.
129. The majority of the human genome encodes a hidden RNA regulatory system that controls differentiation and development. MGC Symposium Lecture, Leiden University Medical Center, Leiden, The Netherlands, September 2006.
130. The human genome as an RNA machine. Centenary Institute of Cancer Medicine and Cell Biology, Sydney, January 2007.
131. The human genome as an RNA machine. Sanger Institute, Cambridge, United Kingdom, March 2007.
132. The human genome as an RNA machine. Novartis, Basel, Switzerland, March 2007.
133. The hidden layer of noncoding RNA in the evolution and development of complex organisms. Department of Biology, University of Milan, Milan, Italy, March 2007.
134. The hidden layer of noncoding RNA in the evolution and development of complex organisms. Department of Biology, McGill University, Montreal, Canada, March 2007.
135. The human genome as an RNA machine. Australian Institute of Biomaterials and Nanotechnology, Brisbane, April 2007.
136. RNA control of brain development, function and memory. Queensland Institute of Medical Research, Brisbane, April 2007.
John Mattick CV Page 54 137. The hidden layer of noncoding RNA in the evolution and development of complex organisms. Department of Biochemistry and Molecular Biology, James Cook University of North Queensland, Townsville, May 2007.
138. The human genome as an RNA machine. Computational Biology Research Centre, Tokyo, Japan, June 2007.
139. The hidden layer of RNA regulatory networks in the evolution and development of complex organisms. Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, August 2007.
140. The human genome as an RNA machine. The Burnet Institute, Melbourne, September 2007.
141. RNA control of brain development, function and memory. Queensland Brain Institute, September 2007.
142. Frontiers in genomics: the human genome as an RNA machine. Center for Genomic Sciences, Universidad Nacional Autonoma de Mexico, Cuernavaca, Mexico, October 2007.
143. The forthcoming explosion in genetic information and in our understanding of the genetic programming of human complexity and variation. Australian Federal Court Conference "Genes to proteins - proteomics in the courts", Sydney, October 2007.
144. The role of RNA in the digital-analog coupling of gene expression and regulation. ACB-BINZ Bioinformatics Student Symposium, Brisbane, October 2007.
145. The human genome: more complex than we imagined. Australian National University (public lecture), Canberra, December 2007.
146. The human genome as an RNA machine. Australian BioInfoSummer07: Mathematical Sciences Institute Summer Symposium, Australian National University, Canberra, December 2007.
147. The human genome as an RNA machine. Leonardo Lecture, Istituto Scientifico San Raffaele and Universita'Vita-Salute San Raffaele, Milan, Italy, March 2008.
148. The human genome as an RNA machine. Cambridge Biological Society, Cambridge UK, March 2008.
149. The amazing advances in genome science and technology. Centre for Military & Veterans Health Think Tank, Canberra, May 2008.
150. The human genome as an RNA machine. Friedrich Miescher Institute (FMI), Basel Switzerland, June 2008.
151. The human genome as an RNA machine. Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France, June 2008
152. Noncoding RNA in cell and developmental biology. Institut de Biologie Moléculaire et Cellulaire (IBMC), Centre National de la Recherche Scientifique, Strasbourg, France, June 2008.
153. The hidden layer of RNA regulatory networks in human development and cognition. Université Pierre et Marie Curie, Paris, France, June 2008.
154. The hidden layer of noncoding RNA in cell and developmental biology. Max Planck Institute for Molecular Genetics, Berlin, Germany, July 2008.
155. The human genome as an RNA machine. Queensland Institutes of Health Symposium, Coolum, August 2008.
John Mattick CV Page 55 156. The influence of DNA on free will. New South Wales Supreme Court Annual Conference, Shoal Bay, August 2008.
157. The eukaryotic genome as an RNA machine. Department of Biology, University of Copenhagen, Denmark, September 2008.
158. The human genome as an RNA machine. St Vincent's & Mater Health Research Symposium, Garvan Institute of Medical Research, Sydney, September 2008.
159. The eukaryotic genome as an RNA machine. Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, October 2008.
160. The eukaryotic genome as an RNA machine. Qiagen, Hilden, Germany, October 2008.
161. RNA-directed epigenetic processes in development, cognition and evolution. Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France, October 2008.
162. The role of non-coding RNA in human evolution, development and cognition. German Cancer Research Centre (DKFZ), Heidelberg, Germany, March 2009.
163. The hidden layer of RNA regulation in the evolution, development and cognition of complex organisms. Institute for Biomedicine, University of Bergen, Norway, March 2009.
164. Noncoding RNAs in the evolution and development of complex organisms. School of Biological Sciences, University of Queensland, Brisbane, April 2009.
165. The central role of RNA in human evolution, development and cognition. The Broad Institute, MIT, Cambridge, Massachusetts, USA, June 2009.
166. The role of noncoding RNA in the evolution, development, functions and environmental responses of complex organisms. Monsanto Corporation, St. Louis, Missouri, USA, June 2009.
167. RNA as the computational engine of the cell. Centenary Institute of Cancer Medicine and Cell Biology, Sydney, June 2009.
168. The hidden layer of RNA regulation in human development and cognition. Murdoch Children’s Research Institute, Melbourne, June 2009.
169. The central role of RNA in human evolution and development. Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, July 2009.
170. The human genome as an RNA machine: the hidden layer of RNA regulation in development, epigenetic memory and brain function. The John Curtin School of Medical Research, Australian National University, Canberra, July 2009.
171. RNA as the computational engine for human development and gene-environment interactions. The Gurdon Institute, Cambridge, UK, September 2009.
172. The central role of RNA in human evolution, development and cognition. Duke-NUS Signature Series, National University of Singapore, Singapore, November 2009.
173. The central role of RNA in human evolution, development and cognition. Science Teachers Association of Queensland, Brisbane, November 2009.
174. The central role of RNA in human evolution, development and cognition. University of Calcutta, Kolkata, India, February 2010.
175. The hidden layer of regulatory RNA in the evolution of developmental and cognitive complexity. Department of Biochemistry & Molecular Biology, Monash University, Melbourne, March 2010.
John Mattick CV Page 56 176. The central role of RNA in the evolution and development of complex organisms. Singapore Developmental Biology Club, Institute for Molecular and Cellular Biology, Singapore, April 2010.
177. The fusion of genetics, genomics and transcriptomics. Bioinformatics Institute Symposium, University of Auckland, Auckland, New Zealand, May 2010.
178. RNA drives epigenetics. Pharmacy Australia Centre of Excellence University of Queensland, Brisbane, June 2010.
179. Regulation of the epigenome. University Medical Center Groningen, Groningen, The Netherlands, June 2010.
180. The central role of RNA in the epigenetic regulation of human development and brain function. Department of Genetics & Pathology, University of Uppsala, Uppsala, Sweden, June 2010.
181. Challenging the dogma: the hidden layer of regulatory RNA in human evolution, development and cognition. Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, July 2010.
182. The central role of regulatory RNA in human evolution, development and cognition. Pasteur Institute, Paris, France, September 2010.
183. New classes and functions of regulatory RNA. Institut de Biologie Moléculaire et Cellulaire (IBMC), Centre National de la Recherche Scientifique, Strasbourg, France, September 2010.
184. RNA as the computational engine of human development and cognition. Department of Biochemistry, Institute of Chemistry, Universidade de São Paulo, São Paulo, Brazil, September 2010.
185. Challenging the dogma: RNA as the computational engine of developmental and cognitive complexity. School of Molecular Bioscience, University of Sydney, Sydney, October 2010.
186. The central role of RNA in human development and cognition. Center for Systems Biology, Soochow University, Suzhou, China, November 2010.
187. RNA as the computational engine of development and cognition. US National Science Foundation, Arlington VA, USA, December 2010.
188. The central role of RNA in human development and cognition. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore MD, USA, December 2010.
189. RNA at the epicenter of systems biology. Institute for Systems Biology, Seattle WA, USA, March 2011.
190. RNA rules. Institute for Molecular Bioscience, University of Queensland, Brisbane, April 2011.
191. The programming of life. Australian Genome Research Facility, Western Australian Institute for Medical Research (WAIMR), Perth, April 2011.
192. RNA rules. Health Innovations Research Institute, RMIT, Melbourne, April 2011.
193. The genomic programming of human development and cognitive plasticity. School of Psychology, University of Queensland, Brisbane, April 2011.
194. The epigenetic programming of human development and cognition. Garvan Institute of Medical Research, Sydney, May 2011.
195. RNA rules. 50th Anniversary Celebration Monash University Department of Biochemistry and Molecular Biology, Melbourne, May 2011.
John Mattick CV Page 57 196. The hidden layer of RNA regulation in animal evolution and development. Stazione Zoologica Anton Dohrn, Naples, June 2011.
197. RNA rules. Department of Physiology, Anatomy and Genetics, University of Oxford, June 2011.
198. RNA at the epicenter of human development. Childrens Medical Research Institute, Sydney, August 2011.
199. RNA at the epicenter of human development. Institute for Molecular Science, LaTrobe University, Melbourne, August 2011.
200. RNA rules. School of Biosciences, University of Birmingham, Birmingham, September 2011.
201. Personal genomics and health. The 20th Annual RBWH Healthcare Symposium, Royal Brisbane and Women’s Hospital, Brisbane, October 2011.
202. Challenging the dogma: a new view of the genomic programming of human development. Peter MacCallum Cancer Centre, Melbourne, October 2011.
203. The genomic programming of development and cognition. Melbourne Brain Centre, November 2011.
204. Revolutionary insights from genome informatics. Bioinformatics Interest Group of South Australia, Adelaide, November 2011.
205. The evolution of complexity. School of Biochemistry and Biotechnology, University of New South Wales, Sydney, March 2012.
206. RNA rules. Somalogic Inc., Boulder, Colorado, April 2012.
207. The hidden role of RNA in human development, cognition and disease. Kolling Institute of Medical Research, Sydney, May 2012.
208. Challenging the dogma: the central role of RNA in the evolution and development of complex organisms. Universidade Federal de Minas Gerais, Belo Horizonte, Brazil, May 2012.
209. The impact of genomics on biology and medicine. Grand Rounds, St Vincent’s Hospital, Sydney, June 2012.
210. Challenging the dogma: RNA at the epicenter of human development. Australian Regenerative Medicine Institute, Monash University, Melbourne, June 2012.
211. The genomic revolution and the emancipation of biology. VIBEnet Workshop, University of Sydney, June 2012.
212. The impact of genomics on biology and medicine. Grand Rounds, Bankstown-Lidcome Hospital, Sydney, June 2012.
213. Challenging the dogma: RNA at the epicenter of human development. School of Medical & Molecular Biosciences, University of Technology, Sydney, August 2012.
214. The genomic revolution and the accelerating pace of change. Notre Dame University Medical School, Sydney, August 2012.
215. Frontiers in genomics: role of non-coding RNAs in the evolution and development of complex organisms. Centro de Ciencias Genómicas, National University of Mexico (CCG-UNAM), Cuernavaca, Mexico, September 2012.
216. Most assumptions in molecular biology and genetics are wrong. Stanford University Department of Genetics Annual Retreat, Monterey CA, USA, September 2012.
John Mattick CV Page 58 217. RNA: the master controller of human development and diversity. Personalised Medicine Workshop, Hunter Medical Research Institute, Newcastle, December 2012.
218. Challenging the dogma: the hidden layer of regulatorty RNA in human evolution and development. Vancouver Prostate Centre, University of British Columbia, Vancouver, January 2013.
219. Challenging the dogma: how molecular biology got it wrong. School of Pharmacy, University of Sydney, Sydney, March 2013.
220. How genome analysis will change medicine and healthcare. St Vincent’s Private Hospital Strategic Panning Workshop, Sydney, March 2013.
221. Most assumptions in molecular biology are wrong. Westmead Millenium Institute, Sydney, April 2013.
222. The hidden layer of RNA regulation in human genetic programming. Kolling Institute of Medical Research, Sydney, May 2013.
223. The hidden layer of RNA regulation in human development. Memorial Sloan-Kettering Cancer Centre, New York, USA, May 2013.
224. Dean’s Distinguished Lecture: The central role of RNA in human development. Weill Cornell Medical College, New York, USA, May 2013.
225. The central role of RNA in human development. RaNA Therapeutics Inc., Boston, USA, May 2013.
226. The hidden layer of RNA regulation in human development and cognition. Scripps Research Institute, La Jolla CA, USA, May 2013.
227. The central role of RNA in human development. Isis Pharmaceuticals Inc., Carlsbad CA, USA, May 2013.
228. The hidden layer of RNA regulation in human development. School of Biomedical Sciences, Monash University, Melbourne, May 2013.
229. Director’s Series School Seminar: The hidden layer of RNA regulation in human development. Research School of Biology, Australian National University, Melbourne, May 2013.
230. Most assumptions in molecular biology are wrong. ANSTO (Australian Nuclear Science and Technology Organisation) Distinguished Seminar Series, Sydney, July 2013.
231. RNA at the epicentre of human evolution, development and cognition. Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle, UK, July 2013.
232. The human genome as the zip file extraordinaire. Department of Cell Biology, Baylor College of Medicine, Houston TX, USA, July 2013.
233. The impact of genomics on the future of medicine and health. Royal College of Pathologists of Australasia NSW/ACT Annual General Meeting, Sydney, September 2013.
234. The hidden layer of RNA regulation in human development. Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Canada, September 2013.
235. The human genome as the zip file extraordinaire. Faculty of Science, University of Geneva, Switzerland, October 2013.
236. The impact of genomics on the future of medicine and healthcare. Jeremy Anderson Oration, Peninsula Health Research Dinner, Frankston, Vic, November 2013.
John Mattick CV Page 59 237. The human genome as the zip file extraordinaire. John Curtin School of Medical research, Australian National University, Canberra, February 2014.
238. Challenging the dogma: a new view of the genomic programming of complex organisms. The Beyond Center and the Biodesign Institute, Arizona State University, Phoenix, USA, March 2014.
239. The molecular basis of human development and cognition. Royal Prince Alfred Hospital Neurology / Neuropathology Meeting, Sydney, April 2014.
240. The impact of genomics on science and medicine. Ingham Institute for Applied Medical Research, Liverpool, NSW, May 2014.
241. Kidson Lecture: The central role of regulatory RNA in human development and cognition. QIMR Berghofer Medical Research Institute, Brisbane, May 2014.
242. The human genome as a programmable and plastic zip file. Pharmazentrum, Basel, Switzerland, June, 2014.
243. RNA at the epicenter of human development. Institute of Human Genetics, CNRS Montpellier, France, June 2014.
244. The central role of RNA in human development and cognition. Institut de biologie moléculaire et cellulaire du CNRS, Strasbourg, France, July 2014.
245. Getting ahead of the curve. PUG Peptide Users Group Symposium, Monash University, Melbourne, July 2014.
246. RNA at the epicentre of human development and cognition. Black Dog Institute, Sydney, August 2014.
247. Development and implementation of clinical genomics. St Vincent’s Institute and St Vincent’s Hospital, Melbourne, August 2014.
248. The transformational impact of genomics on medicine and healthcare. Public Lecture, Griffith University, Gold Coast, August 2014.
249. Most assumptions in molecular biology are wrong. Westmead Hospital Research Week Symposium, Sydney, August 2014.
250. The impact of genomics on medicine and healthcare. Medibank, Melbourne, September 2014.
251. The transformational impact of genomics on medicine and healthcare. AMCHAM (American Chamber of Commerce in Australia), Sydney, November 2014.
252. The impact of genomics on science and medicine. Hunter Medical Research Institute, Newcastle, January 2015.
253. The impact of genomics on medicine and pharmaceutical development. Janssen J&J Annual Conference, Sydney, February 2015.
254. Why would people want to read and cite your papers? BioMed Central Roadshow, The University of Sydney, February 2015.
255. The revolutionary impact of genomics on healthcare and the economy. Australian Press Council, Sydney, May 2015.
256. The impact of genomics on science and medicine. International Laboratory for Human Genomic Research, National University of Mexico (UNAM), Querétaro, Mexico, June 2015.
John Mattick CV Page 60 257. Challenging the Dogma. ANU (Australian National University) Emeritus Faculty Annual Lecture, Canberra, June 2015.
258. The revolutionary impact of genomics on medicine and healthcare. University of New South Wales Rural Clinical School, Port Macquarie Base Hospital, July 2015.
259. Douglas Ormonde Butler Memorial Lecture: Hidden layers of hard- and soft-wired information in the human genome. The University of Queensland, Brisbane, September 2015.
260. Douglas Ormonde Butler Memorial Public Lecture Public Lecture (BrisScience): The revolutionary impact of genomics on medicine, healthcare and the economy of the 21st century. Cultural Centre, Brisbane, September 2015.
261. The central role of regulatory RNA in human development and brain function. RIKEN, Waco (Tokyo), Japan, January 2016.
262. The misunderstanding of molecular biology. Cell and Molecular Biology Training Program Symposium, Case Western Reserve University, Cleveland OH, USA, January 2016.
263. RNA at the epicentre of human development and cognition. Cell and Molecular Biology Training Program Symposium, Case Western Reserve University, Cleveland OH, USA, January 2016.
264. The transformation of medicine through genome sequencing. Healthcare of the Future Conference, Society of Medical Innovation, University of New South Wales, Sydney, Australia, March 2016.
265. Next gen neuroscience: clues from genomics, transcriptomics and strage observations. Neuroscience Leaders Workshop, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada, April 2016.
266. Clinical genomics in Australia. Genome British Columbia, Vancouver, Canada, April 2016.
267. The reformation of molecular biology and evolution. Institute for Molecular Bioscience, University of Queensland, Brisbane, May 2016.
268. The Australian Genome Program. Illumina PopSeq Leaders Council Meeting, Little Chesterton (Cambridge), UK, May 2016.
269. The Future of Genomics Research. Scientific Symposium and Celebration in memory of Georges C. St. Laurent III, PhD, Washington, DC, USA, September 2016.
270. Biomedical discovery in warp drive: the integration of genomic data, clinical records, the internet of things and machine learning. Institute for Molecular and Celllar Biology, Singapore, October 2016.
271. Biomedical discovery in warp drive: the integration of genomic data, clinical records, the internet of things and machine learning. Centre for Pattern Reconition and Analysis (PRsDA), Deakin University, Geelong, Australia, November 2016.
272. The central role of RNA in human evolution and development. The 2016 Ian Constable Lecture, Lions Eye Institute and the UWA Institute of Advanced Studies, University of Western Australia, Perth, December 2016.
SCIENTIFIC AND ACADEMIC SERVICES
Scientific Journals • Bioessays – Editorial Board
John Mattick CV Page 61 • RNA Biology – Editorial Board • PLoS Computational Biology – Editorial Board • Genomic Medicine – Editorial Board • Genome Research - Editorial Board • Gene - Advisory Board • Asia-Pacific Journal of Molecular Biology and Biotechnology - Editorial Board • HFSP Journal - Reviewing Editor • Journal of Law and Information Science - Editorial Board • Silence - Editorial Board • Cell Research - Editorial Board • eLife – Editorial Board
The University of Queensland • Member, Faculty of Science 1989-1996 • Member, Faculty of Medicine / Health Sciences 1990-1996 • Member of the Executive, Faculty of Chemical and Biological Sciences 1997-1999 • Member, Butler Memorial Fund Lecture Committee 1991-2000 • Member, Academic Board 1989-2005
Other Institutions • Member, NHMRC C.J.Martin Fellowships Referee Panel 1990 • Member, Australian Wool Corporation Genetic Projects Review Group 1990 • Member, Selection Committee for the Australian National Genome Information Service 1990 • Member, NHMRC Fogarty Fellowships Committee 1991-1992 • Member of Organizing Committee, the Xth Australian Biotechnology Conference, Gold Coast, Queensland, 1991 • Organizer/Convener, the 14th Annual Conference on the Organization and Expression of the Genome, Lorne, Victoria, 1992 • Member, Review Committee of the Molecular Parasitology Program, CSIRO Division of Tropical Animal Production 1992 • Member, Quinquennial Review Committee of the Garvan Institute for Medical Research 1992 • Member, Hamilton NHMRC Program Grant Review Committee 1992 • Member, NHMRC Genome Working Party 1991-1993 • Member, Biomedicine Advisory Board of the Australian Nuclear Science and Technology Organisation 1991-1994 • Member, NHMRC Assigners Panel 1990-1995 • Member, Martin NHMRC Program Grant Review Committee, 1995 • Member, Joint Review of the John Curtin School of Medical Research, Australian National University, 1995 • Member of Organizing Committee, the 8th International Conference on Isozymes - Gene Families: Structure, Function, Genetics and Evolution. Brisbane, Queensland, 1995 • Chair, NHMRC Genome Working Party 1994-1996
John Mattick CV Page 62 • Member of International Advisory Committee, the 10th International Biotechnology Symposium. Sydney, New South Wales, 1996 • Foundation Director, Lorne Genome Conference Inc. 1992-1997 • Member of Council, Royal Society of Queensland, 1996-1997 • Member, Scientific Advisory Committee, Cooperative Research Centre for Vaccine Technology, 1996-1997 • Member, Organizing Committee of the 19th Annual Conference on the Organization and Expression of the Genome, Lorne, Victoria, 1997 • Member, Review Committee of Research at the Royal Adelaide Hospital, IMVS and the Hanson Centre, 1997 • Member, NHMRC Regional Grants Interviewing Committee 1988-1992, 1994, 1998 • Chairman, NHMRC Regional Grants Interviewing Committee 1992, 1994, 1998 • Member, Research Review Committee of the Prince Charles Hospital, Brisbane, 1998 • Member, Organising Committee of HGM'98 (Human Genome Meeting), Turin 1998 • Member, Board of Pacific Oligos Pty. Ltd., 1997-1999 • Member, Board of the Cooperative Research Centre for The Discovery of Genes for Common Human Diseases, 1997-1999 • Chair, Organising Committee of HGM'99 (Human Genome Meeting), Brisbane 1999 • Chair, Initial Quinquennial Review of the Victor Chang Heart Research Institute, 1999 • Member, Organising Committee, IXth International Congress of Bacteriology and Applied Microbiology, Sydney, 1999 • Member, Program Committee ASM Pseudomonas ’99 Conference, Maui, Hawaii, 1999 • Member, Board, Mater Medical Research Institute, 1999 • Member, Executive and Board of the Australian Genome Information Centre 1991-2000 • Co-Editor (with Prof. Paul Davies), Frontiers of Science series (Allen & Unwin), 1999-2000 • Member, Organising Committee of HGM'2000 (Human Genome Meeting) Vancouver, 2000 • Member, Scientific Advisory Board, Medica Holdings Pty. Ltd., 1999-2001 • Invited Expert Witness, NZ Royal Commission on Genetic Engineering, 2001 • Invited Participant, EINSHAC Conference in Hawaii on Genetics and the Law, which was attended by senior judiciary from the U.S., Australia and other countries, 2001 • Member, Research Review Committee of the Adelaide Women’s and Children’s Hospital, 2001 • Member, Scientific Advisory Board of Benitec Pty. Ltd., 2001 • Member, Board of the Australian Proteome Analysis Facility, 1999-2002 • Member, Board of Genset Pacific Pty. Ltd., 2000-2002 • Member, Queensland Biotechnology Advisory Council, 2000-2002 • Member, Advisory Board of the Research School of Biological Sciences, The Australian National University, 2001-2002 • Member, Review Panel, Genome Canada Competition II, 2002 • Member, Scientific Advisory Committee, COMBIO2002 • Member, Board of Directors of Benitec Pty Ltd, 2002 • Member, Research Committee of the National Health and Medical Research Council, 1997-2003 • Member, NHMRC Australian Health Ethics Committee, 1997-2003
John Mattick CV Page 63 • Member, AHEC Committee to Revise the Ethical Guidelines on Assisted Reproductive Technology, 2001-2003 • Chair, Scientific Advisory Board of Benitec Pty. Ltd., 2002-2003 • Member, Scientific Program Committee, XIX International Congress of Genetics, 2003 • Member, Organising Committee and Scientific Program Committee, Intelligent Systems in Molecular Biology (ISMB) Conference, 2003 • Chair, International Review Committee, Centre for Molecular Biosciences, University of Ulster, Northern Ireland, 2003 • Invited Participant, EINSHAC Conference in Sydney on Genetics and the Law, which was attended by senior judiciary from the U.S., Australia and other countries, 2003 • Chair, Genome Canada Competition I Interim Review, 2003 • Reviewer, Initial Projects, Okinawa Institute of Science and Technology, Japan Science and Technology Agency, 2003 • Member, Advisory Board of the John Curtin School for Medical Research, The Australian National University, 1997-2004 • Non-Executive Director, Australian Genome Research Facility (AGRF), 2003-2004 • Chair, Scientific Advisory Committee and Quinquennial Review of the Victor Chang Cardiac Research Institute, Sydney, 2004 • Chair, Genome Canada Competition II Interim Review, 2004 • Member, Advisory Committee, Ironside State School Centre of Excellence in Primary Science Education, 2002-2005 • Member, Scientific Advisory Group, International Wheat Genome project (IGROW), 2002-2005 • Chair, International Scientific Advisory Board, Centre for Molecular Biosciences, University of Ulster, Northern Ireland, 2005 • Chair, Genome Canada Review of Genome Centre Renewals, 2005 • Member, International Scientific Advisory Board, Centre for Molecular Biosciences, University of Ulster, Northern Ireland, 2002-2006 • Chair, Thinking Systems Panel, Australian Research Council, 2006 • Chair, Genome Canada Review of Applied Health Projects and Programs, 2006 • Member, Advisory Committee of the Centre for Biophotonics and Laser Science, University of Queensland, 2003-2007 • Chair, Queensland Studies Authority, 2004-2007 • Editor, Genome Research, 2005-2008 • Member, Council of Scientists, Human Frontier Science Program, 2005-2008 • Member, RIKEN Genomic Sciences Center Advisory Council, 2005-2008 • Reviewing Editor, HFSP Journal, 2006-2009 • Member, National Program Committee, Epigenetics 2009 Conference, Melbourne, 2009 • Editor, RNA Biology, 2003–2010. • Member of the Scientific Expert Advisory Committee, Australian Research Council Centre of Excellence for Integrative Legume Research, 2003-2010 • Editor, Genomic Medicine, 2005-2010 • Member, Editorial Board of the Journal of Law and Information Science, 2006-2010
John Mattick CV Page 64 • Reviewer and Subcommittee Chair, Large-Scale Applied Research Project Competition, Genome Canada, 2010 • Member, Forensic Expert Reference Group, Queensland Police, 2005-2011 • Editor, PloS Computational Biology, 2005-2012 • Member, National Collaborative Research Infrastructure Strategy (NCRIS) Characterisation Council, 2010-2012 • Member, Malaysian Biotechnology International Advisory Panel, 2010-2012 • Member, Scientific Advisory Board, Liggins Institute for Medical Research, Auckland, 2001-2012 • Member, Editorial Board of Silence, 2009-2013 • Member, ARC Laureate Fellowships Selection Panel, 2013 • Member, Editorial Board eLife, 2012-2014 • Foundation Member, Asia-Pacific International Molecular Biology Network, 1998-2015 • Member, Advisory Panel, Universiti Kebangsaan Malaysia – Malaysia Technology Development Corporation (UKM-MTDC) Biotechnology Academy, 1999-2005 • Member, Steering Committee, Ramaciotti Centre for Genomics, University of New South Wales, 2000-present • Deputy Chair, Scientific Advisory Board of the Liggins Institute for Medical Research, Auckland, 2001-2005 • Editor, Bioessays, 2003-2013 • Member of the Governing Council and Vice President, Asia-Pacific International Molecular Biology Network (IMBN), 2003-present • Member, Advisory Board, ARC Centre for Kangaroo Genomics, 2004-2010 • Specialist advisor for the HUGO (Human Genome Organization) Gene Nomenclature Committee for non-coding RNAs, 2006-2010 • Member, Scientific Advisory Committee, Bioplatforms Australia, 2008-present • Member, Editorial Board of Cell Research, 2010-present • Member, 2002-2010, and Chair 2010-2014, Research Advisory Board, Peter MacCallum Cancer Research Centre • Member, Editorial Board IUBMB Life, 2012-present • Member, Executive Council, St Vincent’s Hospital Campus, 2012-present • Member, Council, Human Genome Organization, 2012-present • Member, Advisory Board of the i3 Institute, University of Trechnology Sydney, 2013-present • Member, Advisory Board, University of Queensland Centre for Clinical Research, 2013-present • Member, Research Advisory Committee, SAHMRI – South Australian Health and Medical Research Institute, 2014-present • Member, Council, Australian Academy of Science, 2015-2017 • Member, Council, Physics Foundation, University of Sydney, 2015-2018 • Member, NSW Government Medical Devices Seeding Fund Expert Assessment Panel, 2015-2018 • Member, Steering Committee, Genome Australia, 2015-present • Member, Science Strategy Panel, Australian Museum, 2015-present • Member, Research Committee, Faculty of Medicine, UNSW Australia, 2015-present
John Mattick CV Page 65 • Member, Shadow Board, AHSP – Academic Health Science Partnership, 2015-present • Member, Expert Panel Competitive Research, National Research Foundation, Singapore, 2016 • Member, Board of Counselors, GIGA Institute, University of Liege, Belgium, 2016 • Member ACOLA (Ausralian Council of Learned Academies) Committee on Precision Medicine, 2016-2017
MEMBERSHIP OF PROFESSIONAL SOCIETIES
• The Australian Society for Biochemistry and Molecular Biology • The Genetics Society of Australia • The Lorne Genome Conference • The Royal College of Pathologists of Australasia • The Human Genome Organization • The International Society for Computational Biology
John Mattick CV Page 66