www.biovision.com preclinical lead identification assayspotency and for developmentthe novelof therapeutics. from the therapeutic to achieve similar and efficacy. safety These becan used as controls for regions variable with technology recombinant using manufactured are antibodies monoclonal Our needs. research hematological malignancies. BioVision is pleased to offer research grade biosimilars in human IgG format for your monoclonal antibodies have received FDA approval for the treatment of solid of a variety tumors and (CDC),cytotoxicity antibody-dependent cellular (ADCC) cytotoxicity or regulation of Tcell Several function. through receptor of apoptosis; induction or blockade cell immune-mediated killing by complement-dependent therapy. Several mechanisms of tumor cell killing by antibodies (mAbs) can summarized be as: action direct Human based monoclonal IgG antibodies (mAbs) are the fastest-growing of therapeutics category for cancer Toll Free: 800-891-9699 (US Only) Toll Free: 800-891-9699 F:T: 408-493-1801 408-493-1800 CA 95035 Blvd, Milpitas, 155 Milpitas S. Anti-CD38 (Daratumumab),Anti-CD38 IgG1 Human Ab Anti-CD33 (Gemtuzumab), Ab IgG4 Human Anti-CD3 epsilon (Muromonab), Ab kappa IgG2a, Mouse (),Anti-CD22 IgG1 Human Ab Anti-CD20 (), Chimeric Ab Anti-CD11a (), Human IgG1 Ab (),Anti-CCR4 IgG1, Human Ab kappa (Arcitumomab), IgG1 Human Ab Anti-Carcinoembryonic (),Anti-C5 Ab Humanized IgG1 Human Ab Anti-Beta-galactosidase, Ab IgG4 (Volociximab),Human 1 beta 5 Anti-alpha Biosimilar Monoclonal Antibodies Monoclonal Biosimilar Antibody Name Name Antibody Cat. No. Cat. A2008 A2005 A2138 A1096 A1089 A1049 A1445 A1443 A2151 A1092 A1104 Trade Name LymphoCide Mabthera Mylotarg Darzalex Raptiva ------Isotype IgG2/4 IgG2a IgG1 IgG4 IgG4 IgG1 IgG1 IgG1 IgG1 IgG1 IgG1 200 µg 200 μg 200 µg 200 µg 200 μg 200 µg 200 µg 200 µg 200 100 μg 100 µg 100 μg 100 Size Antibody Name Cat. No. Trade Name Isotype Size Anti-CD4 (Campath-9H), Rabbit IgG, kappa Ab A2012 - IgG 200 μg Anti-CD4 (), Human IgG4 Ab A1091 - IgG4 200 µg Anti-CD40L (), Human IgG1 Ab A1094 Antova IgG1 200 µg Anti-CD41 (), Rabbit IgG, kappa Ab A2006 - IgG 200 μg Anti-CD52 (Campath-1H), Human IgG1 Ab A1105 Campath IgG1 200 µg Anti-CD6 (), Humanized Ab A2164 - IgG1 100 μg Anti-CD80 (), Human IgG1, lambda Ab A2011 - IgG1 200 μg Anti-CTLA-4 (), Humanized Ab A2110 - IgG1 100 μg Anti-CTLA-4 (), Human IgG2 Ab A2163 - IgG2 100 μg Anti-EGFR (Cetuximab), Chimeric Ab A1047 Erbitux IgG1 100 µg Anti-EGFR (Matuzumab), Human IgG1 Ab A1090 - IgG1 200 µg Anti-EGFR (Panitumumab), humanized Ab A1050 Vectibix IgG1 100 µg Anti-EGFR domain III (Nimotuzumab), Human IgG1, kappa Ab A2004 - IgG1 200 μg Anti-Flavivirus group antigen, Human IgG1 Ab A1102 - IgG1 200 µg Anti-HER2 (Pertuzumab), Humanized Ab A2111 Perjeta IgG1 100 μg Anti-HER2 (Trastuzumab), humanized Ab A1046 Herceptin IgG1 100 µg Anti-Human Ephrin Type A receptor 2 (1C1), Human IgG1 Ab A1095 - IgG1 200 µg Anti-IgE (), Humanized Ab A2145 - IgG1 100 μg Anti-IGF-1R (Teprotumumab), Human IgG1 Ab A2160 Tepezza IgG1 100 μg Anti-IL-12β (), Human IgG1 Ab A2137 - IgG1 100 μg Anti-IL-17Rα (), Human IgG2 Ab A2155 Siliq, Kyntheum IgG2 100 μg Anti-IL-17α (), Humanized Ab A2149 Taltz IgG4 100 μg Anti-IL-17α (), Human IgG1 Ab A2154 - IgG1 100 μg Anti-IL-1β (), Human IgG1 Ab A2144 - IgG1 100 μg Anti-IL-23α (), Human IgG1 Ab A2147 - IgG1 100 μg Anti-IL-23α (), Humanized Ab A2159 - IgG1 100 μg Anti-IL-2R alpha (CD25) (), Human IgG1 Ab A1098 Simulect IgG1 200 µg Anti-IL-2R alpha (), Human IgG1 Ab A1099 Zenapax IgG1 200 µg Anti-IL-4Rα (), Human IgG4 Ab A2148 Dupixent IgG4 100 μg Anti-IL5 (), Humanized Ab A2158 - IgG1 100 μg Anti-IL-5Rα (), Humanized Ab A2162 Fasenra IgG1 100 μg Anti-IL-6 receptor (), Human IgG1 Ab A1447 Actemra IgG1 200 µg Anti-IL-6Rα (), Human IgG1 Ab A2133 - IgG1 100 µg Anti-Integrin alpha 4 (), Human IgG4 Ab A1444 Tysabri IgG4 200 µg Anti-OX40L (), Human IgG1 Ab A1088 Xolair IgG1 200 µg Anti-PCSK9 (), Human IgG1 Ab A2153 Praluent IgG1 100 μg Anti-PD-1 (), Humanized Ab A2132 - IgG4 100 µg Anti-PD-1 (), Humanized Ab A1307 Opdivo IgG4 100 µg Anti-PD-1 (), Humanized Ab A1306 Keytruda IgG4 100 µg Anti-PD-1 (Sintilimab), Human IgG4 Ab A2156 - IgG4 100 μg Anti-PD-1 (), Humanized Ab A2131 - IgG4 100 µg Anti-PD-1 (Toripalimab), Humanized Ab A2161 - IgG4 100 μg Anti-PD-L1 (), Humanized Ab A1305 Tecentriq IgG1 100 µg www.biovision.com www.biovision.com

2 Antibody Name Cat. No. Trade Name Isotype Size Anti-PD-L1 (), Human IgG1 Ab A2152 - IgG1 100 μg Anti-PD-L1 (), Human IgG1 Ab A2109 - IgG1 100 μg Anti-RSV (Felvizumab), Human IgG1 Ab A1446 - IgG1 200 µg Anti-TAG 72 (Satumomab), Mouse IgG1, kappa Ab A2017 - IgG1 200 μg Anti-TNF alpha (Humicade), Human IgG4 Ab A1093 Humicade IgG4 200 µg Anti-TNF alpha (), Human IgG1 Ab A1097 Remicade IgG1 200 µg Anti-TNFSF11 (), Human IgG2 Ab A2150 IgG2 100 μg Anti-TNF-α (), humanized Ab A1048 Humira IgG1 100 µg Anti-TNF-α (), Humanized Ab A2142 - G1 100 μg Anti-TNF-α (), Human IgG1 Ab A2141 - IgG1 100 μg Anti-V5 epitope tag, Human IgG1 Ab A1103 - IgG1 200 µg Anti-VEGF (), humanized Ab A1045 Avastin IgG1 100 µg Anti-VEGF-A Humanized Ab A2136 - IgG1 100 μg Anti-VEGFR2 (), Human IgG1 Ab A2139 Cyramza IgG1 100 μg Anti-α4β7 Integrin (), Humanized Ab A2140 Entyvio IgG1, 100 μg Human IgG4, κ Isotype Control Ab A1101 - IgG4, 200 µg

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