March ), 1991 Vol. XLIII No. "Still U.S. Department of Health The Serond and Human Services Best Thing About Payday" National Institutes of Health e Recori A Year in the Life... New Drug Shown To Benefit Hereditary Immune Disorder Project Turns High Schoolers Into NIH Researchers By Laurie K . Doepel By Carla Garnet< A new drug chat enhances the immune Afore than half their year-long NIH stay is with fresh eyes and eager ears, and just as response has had dramatic success in treating over, but the time has been well spent. importantly, additional hands. the hereditary immune disorder chronic gran They know the language now and they cas To the students, it meant leaving school 4 ulomatous disease (CGD), scientists reported ually toss around phrases like "subdoning a days a week after lunch en route ro the Jab, in a recent issue of New England Jonrnal of gene" and "subject to mutagenesis," phrases forfeiting most extracurricular activities and Medicine. The drug, recombinant gamma peculiar to medical research milieus. free time with friends, and volunteering for interferon, reduced the frequency of serious They know the basic techniques and they extra science assignments and homework. To infections by about 70 percent in patients confidently pipette murky liquids into or out their futures, their decision meant the chance with CGD. A genetic defect leaves people of designated containers. They look like they of a lifetime. with CGD vulnerable to certain life know what they are doing. They are familiar "Working at NIH is a far different threatening infections. The drug was twice as fixtures in their various research experience than anything I would normally effective as antibiotics, the current mainstay of environments-and the oldest among them find in high school or even in college," said CGD treatment. just celebrated his l7 ch birthday about 2 Stacy Marcus, a 16-year-old Kennedy High "These findings are important not only weeks ago. School student working in NICHD's Labora because they will help children with CGD, Encouraged co don N IH labcoats and tory of Molecular Genetics. but also because we now have a precedent for explore dajJy hands-on research, nine .. It's a rare experience to be in high school Montgomery County high school juniors came and working in a lab," agreed Gaithersburg co campus last June and decided ro stay. junior Tony Scott, 16, who is thinking of Their decision meant a loc of things ro a lot majoring in pre-med studies in college. He of people: To NIH's then newly created Office works in the Laboratory of Biological Chemis of Education, it meant a chance to co-launch, try at NCI. 'Tm learning things I wouldn't with the Howard Hughes Medical Institute, ordinarily learn and learning chem on a much the office's first pilot projecc co attract young higher level," he said. would-be scientists. To institute researchers, it (See STUDENTS, Page 6 ) meant an opportunity co share their science New Paging Device Available Mainly Affects Women To the Hearing Impaired Conference Weighs Surgery Risks in HPT Patients By Anne Barber By Jane DeMouy A rthur Lee Jones recently received a gift--a paging device. Jones will wear the device at F or some patients with asymptomatic pri all times while at work. This special pager mary hyperparachyroidism (HPn, con assists hearing-impaired employees in the scientious monicoring is an appropriate airer event of an emergency by vibrating and then native co surgery, according to a recent NIH displaying a message telling the wearer which consensus panel convened by NIDDK and the building is being evacuated. Office of Medical Applications of Research. The pager is part of a system char has been Primary hyperparathyroidism is usually installed in Bldgs. 7, 8, 13, 30, 3 1, 36, 38 caused by a benign tumor of one of the four and 4 1 where there are identified hearing parathyroid glands, which releases parathyroid impaired employees. "We are now working on CGD patient .JameJ Mann, at age 4, plays with hormone (PTH), which in turn aces co raise Bldgs. 4, 9, 29, 29A and 38A," says Richard his moiher at the Clinical Center playground. blood calcium. Hyperparachyroidism can cause E. Shaff, chief, Emergency Management bone loss with potential fractures, kidney Branch. testing gamma interferon in other patients problems, neuromuscular weakness, and ocher If ~•ou know of any hearing-impaired with compromised immune defenses who are common sympcoms. Removal of the affected employees located in buildings nor identified susceptible to recurrent infections such as gland by an experienced surgeon is a highly here, please notify Shaffs office, 496-1985. If patients on cancer chemotherapy, neonates, successful treatment for primary you are hearing impaired and need a paging the aged, and victims of trauma," said Dr. hypcrparathyroidism. device, contact your administrative office. John l. Gallin, director of NIAID's Division Mulriphasic screening tests are now identi According co Libby McKnight, a sign lan of Intramural Research and one of the seven fying approximately 100,000 new cases of guage interpreter in the Division of Equal principal investigators on the study. HPT in the United Stares annually, but Opportunity, NIH has approximately 40-45 The International Chronic Granulomatous because many of these patients have no symp deaf employees. Disease Cooperative Study Group, composed toms other than elevated levels of calcium, Jones works as an animal caretaker for of researchers at 13 medical centers world their treatment has been controversial. The N INOS in Bldg. 36, and had to depend on wide, conducted the study under the risk of hyperparathyroidism increases with age, coworkers to locate him in case of evacuation. sponsorship of Genentech, Jnc. , of South San (See HPT, Page 2 J HPT considered cost effective. They may be useful, (Continued from Page 1.J however, if a previous operation failed. Finally, the panel called for a randomized, and occurs most often in postmenopausal multiccnter clinical trial to compare surgical women. and medical management of HPT and for [n discussing the "Diagnosis and Manage basic research on the pathogenesis of the con ment of Asymptomatic Primary dition and the development of pharmacologic Hyperparathyroidism," che panel said diag treatmencs for the disease. D nosis of H PT is based on two findings pcrsiscenc hypercalcemia and elevated scrum parathyroid hormone. New immunoassays for DCRT Holds Seminar on Mac PTH have helped improve diagnosis. Software for Scientists Some paciencs may present without signs or Software for the Macint-osh has developed symptoms of the disorder. These patients need rapidly in the last few years, with a wide not have surgery, the panel said, if a baseline range of application programs now available evaluation finds no evidence of complications for scientists. Areas of potential interest co and they are conscientiously monitored for NIH researchers include extremely user progression of the disease. friendly systems for statistical analysis, The panel said that a patient qualifying for publication-quality graphics and charting, nonsurgical management must have serum cal powerful numerical computation and extensive cium that is only mildly elevated, no previous special function libraries, full "what you see is episodes of life-threatening hypercalcemia, and what )'OU get" palette-driven equation and for normal kidney and bone status. Surgery would mula setting for rapid PostScript scientific text be indicated for an asymptomatic patient with preparation, and gene sequencing information Geraldine Dietz Fox, chair of the N IDCD any of the following: markedly elevated serum and data management. Advisory BoaYd, was named a winner of the DiJ calcium; a history of an episode of life On Apr. 3 and 4, the DCRT Computer tinguished Service Award from the American threatening hypercalcemia; reduced creacinine Center Training Unit will cover these areas in Speech-Language-Hearing Association (ASHA ). clearance; presence of kidney scone(s) detected six 90-minute modules that will present The award was presented by Roy A. Koenigsknecht, by abdominal radiograph; a markedly elevated expert introductions co: past president of ASHA, "for her tit"eless work O!I 24-hour urinary calcium excretion; or substan • )MP, from SAS Institute: statistics, behalf of the 24 million Americans with speech, tially reduced bone mass. The panel also exploratory data analysis and graphics. language and hearing disorders who will be11efit advised surgery where followup is unlikely, a • SYSTAT, from Intelligent Software: full from the research supported by the institute." coexistent illness complicates management, or featured statistics and plotting system. the patient is less than 50 years old, since the • KalcidaGraph, from Synergy Software: effects of decades of asymptomatic HPT are curve fitting and statistical graphics. unknown, and younger patients will have a • Mathematica, from Wolfram Research: longer life expectancy over which monitoring The NilI Record intensive numerical computations, 2 and 3-D Publ;shed biweekly at Bethesda, Md., by the Editorial must occur. plotting, symbolic manipulation, advanced The choice between surgery and medical Opera,ions Branch, Division of Public Information, for the equation solving, extensive function library. information of employees of rhe Narion.al lnstirutes of management should be '"founded on clinical • MathType, from Design Science: palette Health, Dcpamnent of Health and Human Services, and judgment on a case-by-case basis," according driven equation and formula typesetting. circulated to nonemployees by subscription only through co panel chair Dr. J ohn Poets, physician-in • Mac Vector, from !BI, Inc.; DNA Strider; rhe Government Prinrjng Office. The content is reprincable chief at Massachusetts General Hospital. How Gene Construction Kit, from TextCo: DNA without permission. Pictures may be available on request. co balance the need to identify skeletal, renal, sequencing and library processing. Use of funds for print ing chis periodical has been approved and ocher complirntions against the burdens An overview of the programs and scientific by chc direccor of che Office of Managemenc and Budget through September 30, I 99 I . and expense of long-term monitoring was a software for the Macintosh will be given by principal concern of the panel. . Dr. James D. Malley of DCRT's Laboratory of N IH Record Offlce Correspondents: For asymptomatic patients who do not have Statistical and Mathematical Methodology. Bldg. 31, Room 2B-03 CC, Karen Riedel Phone 4%-2 l 25 OCRT, Anica S. Ferguson surgery, the panel recommended they be Class members are encouraged to attend just evaluated semiannually co establish chat the FAX 402-1485 DRG, N. Sue Meadows those modules of g reatest interest to them, l•IC, Louise Williams disease is nor progressing. Once stability of but course enrollment is required as space is Editor NCI, Pacricia A. Newman these parameters is established in 1 to 3 years, limited. Call 496-2339 to reserve a place. D Richard McManus NCHGR, Leslie Fink testing can occur less frequently. Patients NCNR, Esther McBride should drink lots of water, get plenty of Assistant Editor NCRR, Polly Onderak CC Art Exhibits Planned Ann_e Barber NE!, Linda Huss exercise, and avoid loop or thiazide diuretics, NHLBI, June Wyman as well as diets with restricted or excess The Clinical Center art galleries will Staff Writer NIA, Carolyn Shanoff calcium. include the following presentations between Ca.rla Garnerc NIAID. Ann C. London The panel advised against the use of expen Mar. 12 and ~fay 7: N IAMS, Barbara Weldon Edicorial Assistant NJCHD, Carol Florance sive imaging techniques such as computed Gallery !--Caroline Huff, acrylic on canvas. Marilyn Berman NIDCO, Gail Blatt tomography, ultrasound, thallium technetium Gallery II- Judy Gallegos, watercolors. NIDDK, Eileen Corrigan scanning or magnetic resonance imaging to Gallery lll-1. McGuff-Silverman , pastel Tix NIH Rerrn-,I reserves the right N IDR ' Mary Daum locate benign tumors before initial surgery. In on paper. to make t0rrt'Ctions, NIEHS Award To Enhance Physicians' Knowledge of Environmental Medicine When a patiem goes to his or her doctor own knowledge or by doing a mini-sabbatical ences is a derivative field drawing on many with an illness arising from an environmental co develop their knowledge in an area related disciplines. In addition we realized chat in a exposure, how likely is the patiem to receive a to environmental health sciences. In addition, field attracting young professionals, ic would diagnosis that correctly relates the illness co awardees will be brought together annually co be better not co limit the award to tenured the environment; If a patient has questions share information, ideas and progress reports faculty members. We have learned as we have about the possible risk of specific environmen so they can gain by each ochers' experiences. gone along." tal exposure, does the physician have the Dr. Anne P. Sassaman, who directs rhe Two studies prompted the establishment of answers or know where to get them? And can Division of Extramural Research and Training che award program. "Illness from che Environ the physician effectively communicate to at NIEHS, which administers the awards, says ment: Meeting the Growing Need for Clinical patients concepts of risk related co environ the institute had no idea how the request for Services," a study by the Institute of Medicine mental exposures? applications would be received. Letters detail of the National Academy of Sciences, Division Two major studies, one from the American ing the award were sent out co deans and of Health Promotion and Disease Prevention, College of Physicians and the ocher from the chairpersons of schools of medicine and which was sponsored in part by NIEHS, led National Academy of Sciences, have pointed osteopathy. Thirty-two applications were directly co the development of the program. our the need for a broader awareness and received, representing about 25 percent of the The ocher study, "Occupational and Environ understanding of environmental and occupa schools of medicine or osteopathy in the U.S. mental Medicine: The Internist's Role," from tional diseases- their prevention, diagnosis, Noc only was the number of applications the American College of Physicians health and and treatment-among primary care physi impressive, but also the quality was very high. public policy committee, made clear the need cians. As a result of these findings, the These were reviewed by the Environmental for knowledge of environmental medicine in a National fnstirure of Environmental Health Health Sciences Advisory Council in January broad segment of che medical community. Sciences has established the Environmental and and will be funded beginning in July. Sassaman points out that the NIEHS awards Occupational Medicine Academic Awards to Congress has responded to the awards pro were desig ned co complement the already strengthen curricula in environmental health gram with enthusiasm ·by providing $500,000 excellent work being done by specialists in sciences in United States schools of medicine for the awards in the current budget. This in occupational medicine and by the National and osteopathy. turn has encouraged NIEHS co plan co open Institute for Occupational Safety and Health. The new awards will provide salary supple the program for applications again in 1991. She notes that the NIEHS program will mentation and certain other specified expenses The awards can be made for up ro 5 years, endeavor co reach physicians seeing those co allow a member of a medical school faculty subject to annual reviews. ''We encourage new patients who may be ill from a chronic co spend at lease half of his or her time on applicants. Certainly some of the applicants exposure co an environmental agent unrelated enhancing the teaching of environmental med not funded in the first round may want co to a work setting, who might not otherwise icine. This enhancement could be in the form screngchen their applications and reapply," receive appropriate care. "We are reaching out of increased availability of courses on the sub Sassaman said. co a broad segment of the medical com ject, or through introduccion of material on "We're relying on applicants co be innova munity. We are not involved in training for a environmental health science in courses already tive," she added. The awards program is subspecialty. We wane to sensitize a broad being offered, or by combining these and per modeled after a similar award made by segment of the primary care physicians and haps ocher innovative methods. NHLBI. others in the medical community ro be alert Recipients will be encouraged to expand "The institute realized that we couldn't to environmental diseases. "-Thomas R. their own educational skills, for example by hold applicants to a sec, core curriculum," Hawkins 0 caking additional course work co extend their Sassaman noted. "Environmental health sci- Cafeteria Has Nutrition Month Recipe Card Promotion March is Nutrition Month. The theme this year is "Play to Reduce the Risk of Disease ... Eat Well to Win," so the GSI Cafeteria Service i$ sponsori ng a promotional g iveaway for NIH employees. Be a Daily Prize Winner: get the "Seay Young at Heare" recipe card with a gold star on the back and win a free cafeteria meal (up to $5). There will be one scar ro find each day at only one of the cafeterias during the month of March. Be a Grand Prize Winner: get the "Stay Young at H eare" recipe card with a red star on the back and win dinner for two (up to $50) at Potomac's Landing. On Friday, Mar. 29, one card in one of the cafeterias will have Bob Mehnert, public infomk:ltion officer al NLM for the past 20 years, was recently i11d11cted into the NIH the red scar. Blood Bank's Hall of Fame upon the occasion of his 100th blood donation he,·e. An NIH'e,· since 1965, Discover the stars at any of the Guest Serv Mehnert has been donating blood since April 1966. Married with three, children and eight grandchildren, ices cafeterias. If you get one, turn in the Mehnert enjoys being able to help Clinical Center patients with his regular blood donatiom. Looking on is scarred recipe card to the cafeteria cashier. No Gail Carter(:), supervisor of the NIH Platelet Cenrer, and N1me Fran Moyer. purchase is necessary. 0 page 4 ~Record March 'i, 1991 CGD (Continued from Pag e I. ) Francisco, the biotechnology compan)' that manufactures the drug. This study marks a high point in decades of research invested in unraveling the basis of the genetic defect in CGD that began in 1957 when the disease was first described. "The finding that gamma inted'eron treat ment dramatically benefits patients with CGD provides an excellent example of how invest ment in basic research can lead co clinically useful payoffs," said Dr. Anthony S. Fauci, NIAID director. lnheri,ed Defect Affects I mmunity CGD actuall)• represents a group of closely related diseases caused by a defect in any one of four genes. The defect can be inherited in different ways-as a dominant trait from one parent, as a recessive trait from both parents, or as a recessive sex-linked trait from the mother. Two-thirds of CGD patients inherit the sex-li nked form of the disease, and thus, like hemophilia, CGD most often affects young boys. Regardless of how a person inherits rhe defect, though, the result is the same: pha Dr. J ohn !. Gal/in, directQr of NIAID'1 DiviJio11 of Intramural Research, disct1Sses the role of phagocytic gocytes, rhe scavenger cells of the immune cells in diseau. He was one ofseven principal investigators st11dying CGD. system, fail to produce the oxygen-rich chemi cals needed to kill most fungal and bacterial length of the lives of CGD patients. of age: 81 percent of those receiving interferon germs. These chemicals-including hydrogen Before 1970, children born with CGD often were free of serious infection after a year as peroxide, hypochlorous acid (bleach), and dido 't live past their 10th birthday. Treat compared with 20 percent of those receiving ocher oxygen-free radicals--are normally toxic ment with antibiotics, introduced in the placebo. The researchers do not know why the to cells. But during a metabolic process 1980's, has helped reduce the average interval treatment was more effective in this age known as the respiratory burst, the immune between life-threatening bacterial infections group. The drug appeared co be most effective system harnesses their toxic potential to work (with no effect, however, on fungal infec in reducing abscesses and infections of the on its behalf. tions). But the onset of a serious infection still lymph nodes, lungs, and deep tissues. The inherited defect also causes excessive requites a long hospital stay for administering Gamma interferon benefitted patients inflammarory reactions manifest in conditions intravenous antibiotics, causing a tremendous regardless of their age and mode of inheritance such as gingivitis (swollen, inflamed gums), stress on affected families. Patients treated of the disease, and whether or not they grossly enlarged lymph glands, and tumor-like with gamma interferon with or without pro received prophylactic antibiotics. The therapy masses called granulomas. While not malig phylactic antibiotics are expected to lead a was well tolerated and caused no serious side nant, granulomas can cause serious problems nearly normal life, with significantly fewer effects. by obstructing passage of food through the and shorter hospitalizations required to man Based on this study, the FDA approved esophagus, stomach, and intestines as well as age their disease. the drug for use in CGD patients last by blocking urine flow from the kidneys and Patients in the current study who received December. D bladder. the gamma interferon required three times Although CGD affects only about 4,000 fewer days of hospitalization for the treatment people worldwide, an understanding of the of serious infections than did patients receiv basis of the disease bears on many ocher ing placebo. Atlantic City Trip, Apr. 12 inflammatory diseases involving problems in The phase 111 , placebo-controlled efficacy this metabolic pathway. Oxygen-free radicals, study involved 128 patients treated at 13 Travel by deluxe mororcoach co Trump's while deficient in CGD patients, arc over medical centers: 10 in the United States and Taj Mahal Casino on Friday, Apr. 12. Cost is abundant in cataracts, vasculitis, rheumatoid one each in The Netherlands, Switzerland, and $25 per person and includes round crip trans arthritis, adult respiratory distress syndrome, Denmark. The average age of che patients in portation from NIH and a casino package of and arrhythmias caused by heart attacks or the study was 15 years old. $10 in coin and S5 in food . Motorcoach will stroke, as well as other diseases. The results showed that gamma interferon leave from Bldg. 3 IC parking lot at 7 a. m. Drug May Limit Hospital Stays markedly reduced the threat of infections. and return ac approximately 9 p.m. Half as many patients receiving gamma inter Sign up for the trip at any R&W location. The scientists predict that the new drug-J feron developed serious infections as did chose For more information, contact the R&W bioengineered form of an immune-enhancing on placebo. Activities Desk, 496-4600. D substance produced naturally in the body The most dramatic treatment effects were will significantly improve both the quality and seen among the 52 patients less than 10 years page 5 ~Record March 5, 1991 New GenBank Programs and Services Available GenBank, a computeriied database of DNA Using GenBank Convex computer should be addressed to the and RNA sequences, now has its Authorln Convex system staff, 496-4823. program available for the Macintosh computer. GenBank's nucleotide sequences are avail Additional information about GenBank is Auchorlo, which has been available for the able on magnetic capes, on compact discs, or available from the concraccor, JncelliGenecics, IBM PC and compatibles for over a year, facil online in several computer systems. For the at ( 415) 962-7 364 (see e-mail address above); itates authors' direct submission of sequence most up-to-dace sequence information, scien or the National Institute of General Medical data. GenBank and scientific journals are now tists can use electronic communications co Sciences project officers, Dr. Irene Eckscrand, asking members of the molecular biology com access the database directly. The GenBank 496-7137 (e-mail address: iae@ nihcu), and munity to submit their sequence data directly Online Service (GOS) is updated nightly and Dr. James Cassatt, 496-7463 (e-mail: to the databank prior to publication. therefore provides an important cool for czj@ nihcu). Questions about data submission Authorln is an easy-co-use software tool sequence retrieval, sequence similarity search are answered by the GenBank subcontraccor, designed to help researchers collate their ing, sequence analysis, and electronic Los Alamos National Laboratory, (505) sequence and annotation data for computer communications. GOS is connected to the 665-2177 (e-mail: genbank%[email protected]). readable submission to GenBank. Authors may Internet computer network, allowing world - Doris Brody 0 enter cheir data in any order and may revise wide eleccronic mail, remote login, and file them ac any time prior to submission. Par transfer to and from your computer. You can tially completed entries may be saved and now dial the GenBank computer directly at Originator of 'Fractals' To Speak completed in a later session. To reduce typ (415) 961-6860, but you will incur long dis tance phone charges. For more information, ing, menus are provided for many of the Dr. Benoit B. Mandelbrot, the originator of call (415) 962-7307, or e-mail your question fields. the theory of fractals and a physicist at IBM's co: consultanc@ genbank. bio. nee. The software features on-screen forms in T .J. Watson Research Center in Y orkcown The Division of Computer Research and which co enter information about the submit Heights, N.Y., will lecture on "The Fractal Technology provides a number of compucer ter of che sequence, literature citations Cosmos," on Wednesday, Mar. 13 at 2:30 based, sequence analysis-related services for associated with the sequence, the source p.m. in Masur Auditorium, Bldg. 10. organism, natural and laboratory hosts, and N IH intramural scientists. The main com Mandelbrot has given his lecture a second biologically significant sequence features. puter on which sequence analysis cools are citle-"Fraccals: For the Pleasure of che Eye Extensive online help is also available. Files available is the NIH Convex System, which and the Pleasure of the Mind." From his syl generated by Authorln are simple text files provides accounts under the Management labus for the talk: "Why is geometry so often and may be copied co a disk and mailed co Fund co NIH intramural investigators. Avail described as 'cold' and 'dry?' One reason may GenBank, or they may be mailed able on the Convex are the GCG (Generics be that clouds are not spheres, mountains are elecrronically to GenBank from computer sys Computer Group), a suite of programs provid nor cones, coastlines are nor circles, and more tems connected co the Biener or Internet ing a plethora of sequence analysis cools as generally, man's oldest questions concerning networks. well as access co several locally maintained the shape of his world were left without If you would like co receive a copy of databases, including GenBank; the National answer by Euclid and his successors. In face, Authorln, which is available from GenBank at library of Medicine-developed BLAST suite of they came co be disdained by machemacicians, no charge, send your name and address co: programs that were developed for very rapid who viewed themselves as increasingly build GenBank, c/o lntelliGenecics Inc., 700 Ease similarity searches against GenBank; PIR (Pro ing theories totally unrelated co anything one El Camino Real, Mountain View, CA 94040 tein Identification Resource); and an can see or feel. (e-mail address: authorin@genbank. bio. nee). expanding set of individual programs chat carry out specific casks related co sequence "By describing some highlights of the the GenBank Curator Program analysis. ory of fractals, l will seek co deprive chis self GenBank has also initiated the GenBank In addition co GenBank, DCRT maintains image of its foundation." Curator Program. If you are familiar with a on the NIH Convex System the current ver Mandelbrot wi ll, through use of compucer domain or family of sequences represented sions of the sequence databases from EMBL generaced shapes, suggest chat "behind some within the database and with the existing (European Molecular Biology Laboratory) and of the mathematicians' wildest creations, and annotation, and have some ideas on how the NBRF (National Biomedical Research Founda unknown co chem, lurked a world that is hard annotation could be improved (for example, co tion), and the following databases: Vecbase to tell from che real one, and a second world reflect similarities in features across entries, co (DNA vector sequences), PIR, Swiss-·Prot chat is purely fantastic, yet surprisingly beau improve existing nomenclature, or co point (protein database from EMBL), and PDB tiful and surprisingly useful fo the scientist." our sequence merges or software chat could be (Brookhaven Protein Dara Bank of protein The second talk in a series of "liscener developed to aid data integrity and valida structural data). friendly" lectures on chaos and fractals, tion), GenBank would like to hear from you. DCRT is also developing a program to Mandelbrot's presentation is sponsored by the Suggestions for work co be done on the provide and support sequence analysis software lncerinsciruce Chaos Council and FAES. 0 database should be submitted co GenBank in for personal computers used by NIH scien the form of informal project proposals, which tists. In the fall, the division distributed will be reviewed by both GenBank and NIH copies of the Internacional Biotechnologies Normal Volunteers Needed Staff. Inc. MacVeccor sequence analysis package, for Authors of successful proposals will travel to which it provides continued support. For The NIMH is recruiting normal volunteers Los Alamos and work with the annotation or information about DCRT's sequence analysis of African-American or Italian descent for a computation staff co carry our the proposed services, call Dr. Peter FiczGerald, 402-1 14 l, blood marker study. Participation requires one project. Travel co Los Alamos, hotel costs, and or Dr. George Michael, 402-1140. To apply blood sample (40cc). Volunteers will be paid subsistence will be covered by the GenBank for a Convex account, call DCRT project con for their participation. Call Kayleen Hadd, contract. trol, 496-6 146. Specific questions about the 496-6565. 0 page 6 The Record March 5, 1991 STUDENTS Photos: Carla Garnert (Continued from Page 1) Based on their school attendance, grades, faculty recommendations and personal essays, Marcus, Scott and seven of their peers were accepted into the NIH/HHMI/Montgomery County School intern program, which specifi cally targets minorities and women for carc:er preparation in science. Every week, Monday through Thursday, the students spend the sec " I 've always lilted science. But science hasn't ond half of their days in NIH laboratories, always bem p1JShed. ScientistJ haven't gotten the averaging about 4 or 5 hours a day. publicity or the glamour like the Donald Trumps Two Montgomery County high school sci have. I didn't know what scientists were really ence teachers also train for half-days here, a lik;. l mean, I thought they were a little like mad move designed co test dissemination of tech scientists--you know, the Frankenstein type." niques learned at NIH co the widest student - Michael Duong, student intern population possible. NIH provided the labs and preceptors, HHM[ donated $80,000 co the program, and Kennedy and Gaithersburg Michael Duong high schools supplied the students. "The aim of this program is co give stu dents and teachers a full sense of che scientific process," said Dr. Michael Fordis, director of NIH's Office of Education. After hands-on lab work at the curring edge of science, "a lot of students- some of whom initially might not be interested in research careers-may suddenly see science as a road to pursue," he said. Tania Moss of Gaithersburg High School has a Joe of career options and is already look ing into several colleges including Xavier, Louisiana State University and Howard Uni Stacy Marcus versity. She decided co cry laborat0ry work because science is one of many school subjects she enjoys and performs well in. 'Tm not sure I want co work in a research lab, but I wanted co be in chis program because I am interested in becoming a doc Tania Moss tor," said Moss, a Louisiana native caught between wanting co go home for college and wanting to scay in chis area. Moss, 16, is originally from Gibsland, La., a small town just outside Shreveport. She spends her four afternoons a week in NIDR's Laboratory of Immunology. "I had no idea what research was all about," she said. "Here, I've learned to produce a project from the beginning stages and I've already worked with lab animals." Moss said her friends chink she is crazy to Tony Scott work for no pay, after normal school hours, giving up what would usually be rime co hang out. "Bue I knew chis was something chat would be good for my future," she said. " I t's rt sacrifice I 'll make fo,· just one year, b11t the Scott's friends envy him the chance co leave benefits L reap will last a lot longer than that ... school legirimacely. "They just don:c know -Ebony Davis, student intern how much work is involved," he said, Ebony Davis grinning. Michael Duong, also of Gaithersburg High, cook a mature view of his fortune as an intern in NICHD's Cell Biology and Metabolism Branch. He is, after all, a bit wiser at 17. "I see this almost like a parc-cime job," he p0ge 7 The Record March 5, 1991 said. "Jc is much more rewarding to me than PAGER are responsible for maintaining the fire alarm any sport. Something I do here may help in system." some small way co unn,vel some mystery. I (Continued from Page 1.J Lanouette remembers, "Bldg. 36 was the don't chink it will, but it could. Every single first building co get the system but there was bit helps, I like co chink." "I felt like I needed this before because I work a flaw in it. lt worked, but nor perfectly." Duong, who has considered myriad pose in many different animal rooms, and I was Dennis Poets, electronics technician in the school professions ranging from law co medi always afraid that people would be so busy Telecommunications Branch, says, "The sys cine to business, said science as an acrracrive they might nor hear or remember which ani tem is fully automatic. Once a fire alarm is career has been shortchanged. mal room I was working in, in case of a fire," accivared, it signals a transmitter located in "I've always liked science," he said. "Bur he said. "Now, I can feel the vibra.tion, look Building lO char in cums sends a predeter science hasn't always been pushed. Scientists and see which building the alarm is actually mined message to all hearing-impaired pagers haven't gotten the publicity or the glamour going off in, and know when ir is cime ro get simultaneously. This alphanumeric message like the Donald Trumps have. I didn't know our." notifies the carrier which building is actually what scientists were really like. I mean, I Getting a paging device system for the in alarm. The entire signalling process takes thought they were a lirrle like mad hearing impaired at NIH is the result of a place in a matter of seconds." scientists- you know, the Frankenstein type." cooperative elforc between the Division of Steven Scala, a technical coordinator for the Before coming to N IH, Ebony Davis of Safety, the N I H advisory committee for Coordination and Planning Branch, DES, says Kennedy High School had a clearer, more employees with disabilities, the Division of much planning went inco selection of chis par realistic image of researchers and science per Technical Services' Telecommunications ticular paging system. The initial study began sonnel: Her mom is an epidemiologist at Branch and the Division of Engineering in November 1988, with DS and DES con Fairfax Hospital. Davis also has more definite Services. ducring studies on various paging systems. career plans in mind. Shaff describes the device as a small, rela "The pager system," Scala says, "was a very "I want co travel," said the 16-year-old tively lightweight alphanumeric display pager serious need. Everyone recognized how impor Daytona Beach, Fla., native who works in that activates whenever an alarm goes off in tant chis was. Teamwork went beyond DS, NIDDK's Laboratory of Biochemistry and any building in which the system has been DES and telecommunications, it demanded Metabolism. "More than likely, I'll choose a installed. "This provides additional protection cooperation from all involved. We estimate specialty in the infectious disease field." co the hearing-impaired person," continues the second round of buildings will be com Shaff, "in chat coverage is ensured in build Like Moss and Duong, Davis said she con pleted by April I." siders herself lucky ro be in the intern ings ocher than their primary worksire." "I am very happy that the alerting proce program. Like all the interns, her school The pager selected for this program does dure is now being implemented," said Shaff. schedule is still loaded with rough, advanced nor require recharging and is powered by a "Ir should provide a greatly enhanced level of placement courses even though she must spend single AA battery, available in the self-service protection to an important segment of our scores. "An alphanumeric 'low battery' indica abour 40 percent of each school week at NIH. NIH population char has, heretofore, been tor is displayed on the pager when the battery "Ir's a sacrifice I'll make for just I year, but dependent on the assistance of ochers during needs to be replaced," Shaff says. emergenoes. the benefits I reap will last a lor longer than Mike Lanouette, an electrician leader in the that," she said. "My mom chinks I've kind of Jones sums up rhe feeling of all deaf Shops Branch, DES, was also involved with overextended myself, bur she supports me. I'd employees when he says, "I am so happy to the program "because the paging syscem is get this pager. It will certainly help me and I tell next year's juniors to chink about chis pro interfaced with the fire alarm system, and we gram really hard. Realize it's going co be a lot will feel safer. " of work, bur it's worth it." These interns have been chosen well. There is a level of maturity, a sense of responsibility, in chem that is rare in individuals so young. Duong defined the feeling. "This is nor like in school where something you do is just going to affecc you," he said. " I feel like I'm part of a ream, here. l'm careful about making a mistake because it could hurt the team. It's going co affect everyone around you. I feel like I'm pan of a bigger machine." D NLM Holds Historical Lecture The National Library of Medicine is spon soring a historical lecture on Wednesday, Mar. 13, at noon in the Lister Hill Center Auditorium, Bldg. 38A. The speaker, Dr. Robert Davis of Case Western Reserve Univer sity, will talk about "Another Kind of Glory: Black Doctors in the Civil War." All are Arthur Lee jo,us ( l) receive., a paging device designed fM 11se by hearing-impaired empl1Jyees from Emergency invited. D Management Branch Chief Richard E. Shaff as Libby McKnight, a sign language interpreter, explains the functions. The pager is now available in Bldgs. 7, 8 , 13, 30, 31 , 36, 38 and 41. page 8 The Record March 5, 1991 NIDDK Scientific Director Jesse Roth Retires Dy Kathy Kranzfelder In 1963, the rail-thin, chain-smoking phy years-from 'infancy' through the real matu megaly, an excess growth hormone state that sician came ro NIH as a clinical associate. rity of an important scientific career," said leads co abnormal bone growth and metabolic Imellecrually gifted and well trained, rhe 29- Gorden. abnormalities. Roch also played a major role year-old endocrinologist quickly outgrew the Dr. Jacob Robbins, chief of NIDDK's in developing radioimmunoassays for the hor role of protege, becoming section chief, then Clinical Endocrinology Branch, hired Roth in mones adrenocorticotropin and vasopressin. branch chief and eventually institute scientific 1963 through the NIH matching program. Io the late l960's Roth, Gorden and Pastan director. Along the way, he quit smoking and Roth's obvious talent and potential led to his showed that circularing insulin is not a uni put on a few pounds, married and thrice appointment as a senior investigator after 2 form entity but rakes several forms, some became a far her, but he never lost his years and chief of the diabetes section I year similar to insulin and ochers resembling an commitment. lacer. insulin precursor molecule. Many other labora ·'Nothing deters Jesse," said Dr. Ed Steers, "Jesse matured very rapidly and became a tories followed up on this pioneering work, deputy director of NIDDK's Division of Intra leader not jusr among his colleagues, but looking for evidence of heterogeneity in other mural Research. "Nothing at all. Jesse's oarionally and internationally," said Robbins. circulating hormones. Roth and Gorden hallmark is his unbridled enthusiasm and his "He did that through his energy, productivity extended their studies to include growth imagination. H is willingness and facility for and also his ability ro break new grounds with hormone. trying anything and everything just know no his ideas." The diabetes section developed "Of perhaps greatest imporrance in Dr. bounds." quickly and by 1974, when it was designated Roth's work has been in che area of hormone Jesse is Dr. Jesse Roth, retiring scientific a branch, Roth was named chief. Seven years action," wrote NIH deputy director for intra director for NIDDK's Division of Intramural later he became NIDDK scientific director. mural research Dr. Ed Rall in 1979, when he Research. Steers, who has worked closely with was NIDDK's scientific director. "While Roth for rhe past 7 years, can speak with many invesrigacors, including his own mentors some aurhoriry about Roch's renaciry, inge Berson and Yalow, had attempted ro demon nuity, enthusiasm, intelligence, humor, strate directly hormone receptors on target imagination, leadership and energy--<:jualirics. tissues, it was J esse Roth and his colleagues Sreers said Roch both possesses and inspires. (Dr. Ira Pastan of NCI and Drs. Robert According to Steers, the intramural division Lefkowitz and William Pricer) who were first was extensively reorganized under Roth. "Jesse successful, with che measurement of ACTH took several individuals who were in bad receptors on adrenal tissues in 1970." situations-for myriad reasons--and through Their seminal work on receprors showed the reassignment and relocation helped creare new essential role of cell surface receptors in opportunities for chem. In addition, he created activating cells and showed that there arc several new labs, and new sections and moved rapid changes in the number and avidity of certain sections out of old laboratories into receptors in response to changes in the new laboratories. He put people in close phys environment and in disease states. The concept ical and scientific contact with each other, of a cell surface receptor represented an which started new directions and new initia encirely new way of understanding the action tives," said Steers. of hormones on target cells. Roch's experi Roth's changes, however, did not always Dr. Jesse Roth ments served as a model for later studies evolve easily. "Understand, too," Steers con showing that many ocher hormones also bind tinued, "that some people were quire upset. Roch came to NIH from rhe Veterans to receptors on the surface of cells. Roch and When you change things, it raises anxiety. Administration Hospital in Bronx, N.Y., his collaborators also contributed significantly But, you know, that's nor necessarily bad. where he was an American Diabetes Associa to our undersranding of how the endocrine We're in a highly competitive, highly anxious tion research fellow. There he worked with sysrem regulates i rself through feedback loops. business, and so a high anxiety level is proba Drs. Solomon Berson and Rosalyn Yalow oo His scudies with Pasran, Lefkowitz and bly more positive than negative. " developing new radioimmunoassays, a now Pricer in many ways opened the field of inves Roth has never been one to quietly observe indispensible technique for measuring circulat tigation into disease states involving insulin without contributing to a situation. "In a ing hormones and numerous other biologically receptors. Roth and his collaborators found crowd you could pick out Jesse quickly important substances. (Berson's and Yalow's insulin receptor defects in diabetes compli because he would usually have something to unique contributions were recognized by rhe cated by obesity, in acromegaly, anorexia say fairly early in the event," said NIDDK Nobel Prize in physiology or medicine co nervosa, lipoatrophic diabetes, and in many director Dr. Phil Gorden, who has known Yalow in 1977 .) ocher forms of insulin resistance. Their studies Roth for the past 23 years. "Jesse usually has While at the Veterans Hospital, Roth of the insulin receptor led them co uncover an excess of ideas to solve any one problem. If reamed up with Dr. Seymour Glick to meas cwo new diseases, both characterized by you need one way to do something, Jesse ure growth hormone secretion and decipher its extreme resistance to the effects of insulin. would offer 10. If you need two, he's got 20. physiology. These studies led to more accurate Those with severe insulin resistance type A Jesse functions on sort of a logarithmic scale cl iagnoses of growth hormone deficiency states have since been shown by Or. Simeon Taylor, in this world." as well as growth hormone excess scares. These chief of NIDDK's Diabetes Branch, and col Roth's cenure at N IDDK is a classic exam rests are still rhe "gold standard" against leagues to have specific inborn defects in the ple of the NIH success story, according ro which all new rests are evaluated. This work insulin receptor molecule, while chose with Gorden, who was recruited to NIH by Roth also served as the foundation for Roch's type B have antibodies that react with and in 1966. "NIH was able to retain Jesse for 27 research at NIH on rhe treatment of aero- thereby disturb their insulin receptors. page 9 The Record March 5, 199 I More recently, Roth has begun exploring Pollen To Direct NIAMS Board STEP Forum Discusses the evolutionary origins of polypeptide hor 'Talking with Reporters' mones, seeking co identify che lowest Geraldine Pollen has been named executive Since both intramural and extramural NIH organisms having molecules related co these director of the National Advisory Board for are often involved in scientific breakthroughs, hormones and recepcors. Arthritis and Musculoskeletal and Skin media interest in NIH is high. The Staff Roth, who graduated from Columbia Uni Diseases. Training in Extramural Programs (STEP) com versity in 1955 and cook his M.D. from She will be responsible for the day-to-day mittee is therefore presenting a forum on Albert Einstein College of Medicine in 1959, management of the board and will serve as "Talking with Reporters." has garnered an impressive list of honors in his liaison with the direcror and the Office of the Who should talk with reporters) What career, including the Lita Annenbcrg Hazen Secretary in carrying out the responsibilities of should you tell reporters? When should you Award and the Mellon Award. From the the board. In addition, she will serve as execu release information? Where, why and how Endocrine Society he received the Ernst tive secretary for the congressionally mandated should you talk with reporters? Oppenheimer Memorial Award in 1974 and arthritis and musculoskeletal diseases inter The forum is scheduled to be held on the Koch Award in 1985; and from the .Amer agency coordinating committee and for the Wednesday, Mar. 27, from I to 3 p.m. , 10 ican Diabetes Association he received the Eli skin diseases inceragency coordinating commit Wilson Hall, Bldg . l. Lilly Award in 1974 and the Banting Award tee. She will also serve as special assistant co The two-panel forum will emphasize using in 1982. In 1989, the University of Rome the proper protocols for reporting scientific conferred an honorary doctoral degree in medi breakthroughs. One panel consists of two cine co Roth, one of Italy's highest academic reporters: Joseph Palca, Science magazine and honors. Larry Thompson, the Washington Post , who In addition co his own accomplishments, will address how science news is reported; the Roth has often been credited with playing a differences between reporting policy issues, vital role in the careers of young investigators health issues, and scientific discoveries; and around the world and thus expanding how NIH staff can increase scientific coverage endocrine research to centers in Europe, Israel in the media. and Japan, as well as around the United The second panel is comprised of two repre Scates. "There are many who make very sentatives from NIH communications offices: irnpnrtant contributions in rheir lives. But Constance Raab, director, Scientific and chose who do chat and make major contribu Health Communications, NIAMS, and Scorm tions to the development of ocher bright, Whaley, NIH associate director for communi talented people-that's an extra dimension cations, Office of Communications, OD. They that Jesse has truly excelled in as a scientist will discuss NIH policies on talking directly and scientific director," said Gorden. with reporters and how co be more effective Last December, more than l50 friends and when talking ro them. colleagues gathered at the Bethesda Naval STEP forums do not require advanced regis Officers' Club to wish Roch well in his new tration and are open ro all NIH personnel. career at the Johns Hopkins School of Medi Geraldine Pollen Attendance will be on a space available basis. cine, where he is professor of medicine and Additional information is available from the director of the division of geriatric medicine the director, NIAMS. STEP program office, Bldg. 3 l, Rm. 5844, and gerontology. Joining him was his wife, Prior ro this appointment, Pollen was chief 496-l493. Susan, and their children- Alisa, 17; Alex of the Office of Information and Legislative 0 ander, 16; and Alana, 11. Affaics, National Center for Nursing Research. ECS Presents Video Series On behalf of Roth's many friends and col She has been a program analyst in the Legisla The Employee Counseling Services con tion and Analysis Branch, NINOS, and a leagues, Or. Simeon Taylor and Maxine rinues co present its new video series on work, Lesniak, Roth's long-time assistant, presented program analyst and special assistant to the career, and personal growth issues co the NIH Roth with several gifts, beginning with a col director, Division of Financial Management, community. The next presentation in the lection of books on American and Italian art, NIH. She is the recipient of several special series is titled "Assertiveness Training." subjects for which Roth has a great apprecia achievement awards including the NIH Merit Award. Pollen is also the coauthor of a book This videotape is divided into four intercon tion. To cease Roth about the endowed chair nected 50-minuce segments. They will be on teaching nutrition to children. that accompanies his new academic poses, he shown on consecutive Tuesdays in March from was also give a tacky, straight-backed chrome A native of New York City, Pollen received noon co 1 p.m. in Conf. Rm. E/F located ac chair with yellow vinyl rnshions, anocher her undergraduate degree in political science Executive Plaza North. A question-and-answer object of his appreciation. Roth, who stands from Barnard College and her master's degree session led by Kathleen Moore of ECS will fol 6'4" tall and suffers from a temperamental in curriculum development and teaching from Columbia University. D low each session. The segments are as follows: back, found his best seated comfort at NIH in Mar. 5: "The Basics of Assertiveness" these chrome and vinyl chairs. His gift chair Mar. 12: "Getting Beyond the Basics" was engraved "The Jesse Roth Endowed Chair NIDR Asks for Volunteers Mar. 19: "Assertiveness Strategies" of Geriatric Management." Taylor and Lesniak Volunteers are needed for an NIDR study of Mar. 26: "Dealing with Others are also gathering reprints of all of Roth's the extraction of third molars (wisdom teeth). Assertively'· publications for binding. D Dental treatment for the removal of wisdom Look for details about the May 7, 14, 2 I teeth will be provided free of charge in and 26 series entitled, "Stress Management for exchange for participation in clinical studies Professionals. " Please contact the Employee evaluating new pain medications. For more Counseling Services, 496-3164, with your information call 496-8896. D questions about this program. D page 10 March 5, 1991 Good Idea Brings Cash A suggestion that has saved NIH laborato ries thousands of dollars during the past year and will save many thousands more has brought a cash award to its originator. Daniel Reggia, a medical equipment repairer in Scientific Equipment Services, Bio medical Engineering and Instrumentation Program (BEIP), NCRR, saw a way to pro long the life and increase the efficiency of carbon dioxide incubators commonly used for growing cells. Laboratories had co replace many outdated or defective incubators yearly ac an average cost of $5,000. Reggia suggested that BEIP stock and use small, newly developed carbon dioxide control devices chat upgrade and renovate such incubators at less than one-fifth the cost of replacement. Electromechanical unit chief Johnny Robbins promptly acted on the sug gestion and later nominated Reggia for a cash award. Howard Metz, BEIP assistant director for scientific equipment services, recently pre sented the award with research Daniel Reggia ( I) accepts cash award from Howard Metz, BEIP assistant director for scientific equipment instrumentation section chief Lewis Cascio and serviw. Looking on are research instrumentation section Chief Lewis Cascio am/Johnny Robbim ( r), Robbins. eie.tmm«hanical unit chief, who nominated Reggia /r,r the award. Nutrition Month Videofest Set The Clinical Center nutrition department C Language Classes Planned Extramural Grants Workshop Set will present a series of nutrition videos during the month of March. Learn successful nutri An unusual opportunity to learn C Lan A workshop on extramural programs and tion strategies and how co apply them. A guage at no cost is being made available co to help postdoctoral registered dietitian will be available to answer _grant support, designed NIH employees through the DCRT Computer fellows understand the research grant process, questions after each of the presentations. All Training Program. A sequence of classes at all will be held in Lister Hill Auditorium, Bldg. videos will be shown in the Little Theater levels is scheduled so a student can progress 38A, on Friday, Apr. 19, from 8:30 a.m. co from noon to l p.m. from the beginning co the advanced level in a 5 p.m. Mar. 5 "Eating to Live, Living to Eat" 2-month period. The workshop, sponsored by the National "Good and Healthy" C is a portable genera.I-purpose language Institute of General Medical Sciences, is Mar. 14 "How co be a Low-Fat Eater in a chat has become the language of choice for intended for intramural postdoctoral fellows, High-Fae World" most advanced applications. C is particularly staff fellows, clinical associates, and research "Tomorrow's Kitchen" popular in the UNIX environment. associates who will be leaving NIH during the Mar. 19 "Eating Healthy for Weight Control'' The C Language program consists of four next year. Others will be considered for par "Eating Healthy for Heart Health" pans: ticipation if space allows. Mar. 28 "Eating Healthy When Dining Out" "Getting Started with C" on Mar. 11, 12, The program will cover the types of federal "Eating Healthy for Life" D 13, 15 from l to 4 p.m.; "C Language fun and nonfederal support available to new inves damcntaJs" Mar. 18-22, 8:30 a.m. to 5 p.m.; tigators, the NIH review process, the fine FAES Summer Grants Available "C Language Workshop" on Mar. 29, 10 a.m. points of preparing a grant application and The FAES will award grants at 3/4 the sti ti! noon; "C Language Data Structures" on appropriate persons to contact with problems pend paid co summer IRTA recipients for Apr. 2, 9, 16, 23, 30 from 9 to 11:30 a.m. or questions. conducting research at the NIH chis summer. All classes will be taught in Bldg. 12A. Small group discussions for answering indi An additional $500 to cover travel and living Call 496-2339 for information or to reserve a vidual questions will be led by experienced expenses might be available if need can be space. D staff people from several institutes and the demonstrated. High school, undergraduate, Division of Research Grants. graduate and medical students who will work Healthy Volunteers Needed Application forms arc avai lable from intra for a minimum of 8 weeks are eligible. mural laboratory and branch chiefs. Applications are available in the FAES busi Healthy volunte~rs, male and female ages Applications muse be returned by Mar. 18 and ness office, Bldg. 10, Rm. B 1Cl8, or by 30 through 65, are needed co participate in should be sent to Extramural Workshop, calling 496-7976. Completed applications studies of endocrine secretion. Volunteers Westwood Bldg., Rm. 9L8. including a description of the research co be must be on no medications, and may partici For additional details, call Dr. Marcus performed and a supporting statement from pate in one or several studies. All volunteers Rhoades, 496-7137. 0 the NIH sponsor muse be received by Apr. 5. will be compensated for their time. If inter Notification of the awards will be made to ested, call the Clinical Neuroendocrinology the NIH sponsor by the end of April. 0 Branch, NIMH, 480-0944. 0 page 11 The Record March 5, 1991 ~ TRAINING TIPS Supporting Family Caregivers Focus of Nurse Lecture, Mar. 6 The NIH Training Center of the Division '"Research Issues: Supporting Family Care of Personnel Management offers the following: givers," will be the topic of the Distinguished Nurse-Scholar lecture on Wednesday, Mar. 6 Cwrse.r and Programs Starting Dater from 7 to 9 p.m. in Bldg. 1, Wilson Hall. Management and S11pervisory 496-637 l The lecture will be presented by Dr. May Using Animals in Intramural Research 414 L. Wykle, Florence Cellar professor and chair Practical Management Approaches 41 17 Creativity with and through G roups 41 J 7 person of psychiatric, mental health and Hands-on Animal Techniques Workshop: 4124 gerontological nursing and director of the Rodenc Tc-choiques University Center on Aging and Health, Case How T o Wri,e and Publish Scientific Papers 4/ 15 Western Reserve University. Special Coune.r 496-6211 The presenration is sponsored by the Basic Employee Relations 4124 National Center for Nursing Research, the Appropriation Law Seminar 4117 Clinical Center nursing department and the Break the Smoking Habit 4/ IO National Institute on Aging. For phone reser Personal Computing Training 496-6211 vation or information, call (30 I) 496- 1330. D Welcome ro Mac 4/1, 41 16 ln During Nutrition Month, Eat Well To Win By Karen A. Donato and Nancy W. Gaston M ore people, more often are eating more of nationwide in a variety of settings including Nutrition Education Efforts their food away from home. Does chat sound business dining facilities, universities and like you? Busy lifescyle, eight work and travel schools, hospitals and retirement homes. Since Efforts have been made by the GSI Cafeteria schedules) then, particularly in September for National Service co supply nutrition education to its The U.S. Department of Agriculture's Cholesterol Education Month and in March NIH patrons. In che past, various NIH nutri Nationwide Food Consumption Survey indi during Nutrition Month, featured heart tion publications have been available at the cates chat adults consume about 30 percent of healthy entrees are offered in the NIH cash registers, particularly in March during their calories away from home; the National cafeterias. Nutrition Month. In recent years, the NIH Restaurant Association cites that more than 43 Last September, 15 additional "Stay Young nutrition coordinating committee (NCC) cents of every food dollar is spent on food ac Hean," recipes were developed for GSI ro developed posters and table tent cards to eaten away from home. These stat istics might incorporate on their menu and now are part of encourage patrons to attend nutrition seminars cause concern for chose who are really "into" their regular fare throughout cb.e year. During and other campus activities during Nutrition getting a nutritious, healthy diet. For NIH March, the "Stay Young at Heare" recipes are Month, and to reflect upon and modify their employees, however, the Guest Services, Inc. highlighted with a red heart on the cafeteria eating behavior and physical activity. Some (GS!) Cafeteria Service on campus. offers hearr menu boards. Nutrition Month themes from past years healthy entrees and other healthy menu selec include: "Reduce the W eight of Your World, tions. March is a good time ro check them Welcome to Your Cafeteria Reduce Your Risk of Disease: Achieve Your out, during Nutrition Month. Desirable Body Weight," "Seay Young at Recently the GSI Cafeteria Service posted Heart," "Learn the Facts ·on Fae, " "Follow che Healthy Eating at Cafeterias green and white boards, entitled "Welcome co Dietary Guidelines Down the Road to Better Your NIH Cafeteria," at each cafeteria's Health," "Ways and Whys of W eight Con With assistance from the NIH nutrition entrance; they describe healthy menu choices trol," "Nurrition and Exercise--Team up for coordinating committee's nutrition education and food preparation methods_ Take a moment Good Health ... the Olympic Way," and subcommittee, the NIH area manager of GS! co read rhem the next time you enter one of "March for Good Nutrition: Take Steps has a long, continuous history of both sup the cafeterias. Against Disease." porting and promoting a healthy eating program for NIH cafeteria patrons. As early as Nutrition Month Acdvities l982, sale-free vegetables, fresh fruits, a salad bar complete wich fresh fruits and vegetables, G-Sttv1tt:815 ...... IO olfrr ti.-opck. The GS! cafeteria's efforts to provide natural drinks, whole grain bagels and breads, ln elldl NIB aifeta'la: nutritious menu selections to NIH patrons and and baked chicken and fish have been avail I ~hJlt-,nlMult;-Gn;nlOlbald-b-""1dwidlos its participation in nutrition education able. Heart healthy lunch menu choices also 2. 'lllOlr ran Haps and 8ra'I ~ activities on campus peak each year in Septem i,ow&l~ot-T""' have been a regular feature in the NIH caf Pastl, ID!o-~ ber (National Cholesterol Education Month) eterias for several years. \ '~()IM.-pft W. Adcili(i(l ktlkilltt and in March for Nutrition Month. This So)-Oilb-f~ March, watch for the cafeteria's nutrition "Stay Young at Heart" 1. 1.ow!a.~M&.«-~--Miltald Imm month heart healthy specials. Daily announce ~ IDw&l,...,,nl __ ..,._..,U)OU!Cm9 ments will appear on the cafeteria's menu One of the many efforts for more nutritious 0- t.oofa_""" Washington area, as well as in 22 states calorie-controlleJ menu choices. l f.S. (;QVF,.RN MF.N T PIU NTING
March 5, 1991, NIH Record, Vol. XLIII, No. 5
