Journal of Advanced Clinical & Research Insights (2019), 6, 86–90 REVIEW ARTICLE Genetics in an orthodontic perspective G. R. Raveendra Varma1, B. Harsha1, Santosh Palla2, S. P. Amulya Sravan3, J. Raju4, K. Rajavardhan5 1Department of Orthodontics and Dentofacial Orthopaedics, KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India, 2Department of Oral Medicine and Radiology, KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India, 3Department of Orthodontics and Dentofacial Orthopaedics, Lenora Institute of Dental Sciences, Rajamundry, Andhra Pradesh, India, 4Department of Orthodontics and Dentofacial Orthopaedics, St Joseph Dental College, Andhra Pradesh, India, 5Department of Pedodontics and Preventive Dentistry, Institute of Dental Education and Advanced studies, Gwalior, Madhya Pradesh, India Keywords: Abstract Gene mapping, gene therapy, genetics, Genetics is the science concerned with the structure and function of all genes in different homeobox, mutations, orthodontics, single- organisms. Malocclusion is a manifestation of genetic and environmental interaction on nucleotide polymorphisms the development of the orofacial region. It is important to consider genetic factors to Correspondence: understand the cause of existing problems, which has influence the outcome of treatment. Dr. G. R. Raveendra Varma, Department of The review aims to provide information to the dental practitioner and orthodontist on Orthodontics and Dentofacial Orthopaedics, basics of genetics and common disorders with gene impairments. These genetic factors KIMS Dental College and Hospital, NH-216, in turn have an impact on outcome of orthodontic treatment. Chaitanya Health City, Amalapuram, Andhra Pradesh, India. Phone: +91-9849411828. E-mail:
[email protected] Received: 16 March 2019; Accepted: 18 April 2019 doi: 10.15713/ins.jcri.267 Introduction to Basics of Genetics ribosomes, mitochondria, and nucleus.