Journal of Dairy & Veterinary Sciences ISSN: 2573-2196

Mini Review Dairy and Vet Sci J Volume 3 Issue 3 - September , 2017 Copyright © All rights are reserved by Kavita R Pandey DOI: 10.19080/JDVS.2017.03.555614 Mini Review on the Dynamic Probiotic-Bacillus coagulans

Kavita R Pandey* Guru Nanak Institute for research and development (GNIRD), G N Khalsa College, India Submission: August 06, 2017; Published: September 20, 2017 *Corresponding author: Kavita R Pandey, Guru Nanak Institute for research and development (GNIRD), G N Khalsa College, India, Email:

Abstract The health conscious consumers have started understanding and gravitating towards probiotic consumption for the rise in documented

probiotic bacteria and yeasts available, Bacillus coagulans is one of the most robust spore forming probiotic which is in high demand by the commercialhealth benefits producers they impart for severalon the hosts.technological Digestive advantages. well-being isThis the mini global review obsession enlists among the reported the rapidly health aging effects population. exerted Amongst by this thedynamic many B. coagulans and also commercial formulations containing them.

probiotic-Keywords: Bacillus coagulans, Probiotics, Commercial production.

Introduction Table 1: Health benefit. maintaining health and disease prevention has been an area Health benefit Reference Health benefits imparted by probitoics and their roles in of extensive research in the past few decades. Some of the Prevents muscle damage during exercise Jäger et al.[6] commonly used probiotics include Lactobacillus rhamnosus, L. Gastrointestinal disorders like IBS and IBD Majeed et al. [8] reuteri, Bacillus coagulans, E. coli Nissle 1917, some enterococci Different types of diarrhea like Antibitoic and yeasts like Saccharomyces boulardii etc. Pandey et al. [1] Majeed et al. [7] associated and travellers diarrhea) Fitzpatrick et al. [4] mechanisms of action) ranging from diarrhea to cancer have reviewed the major health benefits (and their probable prevention etc. One of the nastiest technological problems ColitisCadmium (induced and by mercury Clostridium poisoning difficile) Jafarpour et al. [5] probiotic fermentation industries face is loss of viable cell Hypercholesterolemia Abhari et al. [2] Gut functions improvement in elderly count during harsh processing conditions. Spore forming Nyangale et al. [9] Bacillus probiotics remain in huge demand due to their ability population to withstand the stringent processing conditions. One of the Treating rheumatoid arthritis Abhari et al. [2] sturdiest probiotics is B. coagulans. Poultry (boosting immunity & growth Park et al. [11] enhancement) Bacillus coagulans Preventing bacterial vaginosis Sudha et al.[12] Bacillus coagulans (discovered in 1930) was formerly known Cancer prevention Azimirad et al. [3] as Lactobacillus sporogenes. B. coagulans is a spore forming Global Probitoic Market acid homofermentatively. B. coagulans is a remarkably resilient The penetration of probiotics in the market is very high. non-pathogenic gram positive bacteria that produces L(+) lactic probiotic that is able to withstand extreme conditions (like high Probiotic foods are available in grocery stores and supermarkets, temperatures, processing, stomach acids and bile) and is room while probiotic supplements are available in pharmacies and health food shops. Moreover, the increasing obsession of digestive makes B. coagulans the favorite of commercial probiotic wellbeing and preventive healthcare has accelerated the market temperature-stable for up to 3 years. Sporulation property producers. Various preparations of B. coagulans in powder, growth. There is increase in number of probiotic ingredient tablet and capsule forms exist in the market imparting several suppliers who develop tailored strains of microorganisms for integrating with a diverse set of probiotics products. diseased conditions (some are enlisted in Table 1). health benefits on the hosts like treatment of prevention of some

Dairy and Vet Sci J 3(3): JDVS.MS.ID.555614 (2017) 001 Journal of Dairy and Veterinary Sciences

Dynamic Probiotic for Commercial Producers Conclusions The probiotic ingredients market is segmented on the basis of B. coagulans strains need a further characterization to rule application into food & beverage (dairy, bakery & confectionery, out the speculations like causative agent for infections in patients meat & cereals, etc), dietary supplements, and animal feed. with catheters and leading to rejections in organ transplants The global probiotic market is dominated by players likeYakult etc. Another lacunae in B. coagulans research is lack of large (Japan), Dupont (Danisco), Ganeden (USA), Sabinsa (USA), scale human trials and uncertainty of dosage amounts due to scanty clinical data. There is a need to evaluate the survival of B. largest market for probiotic products and ingredients with Japan coagulans during manufacturing process and storage conditions BioGaia (Sweden), Nestle (Switzerland) etc. Asia-Pacific is the having accounted for a major share. The dietary supplement segment is projected to grow at the highest CAGR of 8.0% from [2-12]. 2015 to 2020. Health effects exerted by any probiotic is strain References B. 1. Park JH, Kim IH (2015) The effects of the supplementation of Bacillus coagulans strains have been enlisted below Table 2. specific. Some of the commercial formulations containing intestinal Salmonella concentration, noxious gas emission, organ Table 2:Commercial probiotic formulations containing Bacillus weightsubtilis and RX7 breast and B2Ameat strainsquality of on broiler the performance, challenged with blood Salmonella profiles, coagulans. typhimurium. Journal of animal physiology and animal nutrition 99(2):

Product Strain Manufacturer 2. 326-334. J (2015) The effects of prebiotic, probiotic and synbiotic diets Ganeden (USA) containingAbhari K, ShekarforoushBacillus coagulans SS, Hosseinzadeh S, Nazifi S, Sajedianfard https://www. rat. Veterinary Science Development 5(2). ganedenprobiotics.com/ and inulin on serum lipid profile in the B. coagulans 3. Staimune J, et al. (2016) The effects of orally administered Bacillus coagulans probiotic-news/news/ andAbhari inulin K, Shekarforoushon prevention and SS, Hosseinzadehprogression of S, rheumatoid Nazifi S, Sajedianfard arthritis in GBI-30, 6086 ganeden-receives-fda- rats. Food & nutrition research 60(1): 30876. gras-on-probiotic-derived- sta 4. Azimirad M, Alebouyeh M, Naji T (2017) Inhibition of immune-health-ingredient- Sporlac R Sanzyme (Japan) B. coagulans and B. subtilis (for aphthous http://sporlac.com/ Lipopolysaccharide-Induced Interleukin 8 in Human Adenocarcinoma stomatitis) Cell Line HT-29 by Spore Probiotics: Suja Probiotics (USA) 5. (natto).Fitzpatrick Probiotics LR, Small and JS, antimicrobial Greene WH, Karpaproteins KD, 9(1): Farmer 56-63. S, et al. (2012) prodsporlac-Ds.aspx Bacillus coagulans https://www.sujajuice.com/ Pineapple probiotic pathogens 4(1): 13. GBI-30, 6086 limits the recurrence of Clostridium enhanced water difficile-Induced colitis following vancomycin withdrawal in mice. Gut products/pressed-probiotic-cayenne/ 6. waters/pineapple-lemon- (2015) Impact of synbiotic diets including inulin, Bacillus coagulans Brad’s plant based andJafarpour Lactobacillus D, Shekarforoush plantarum SS,on intestinal Ghaisari HR,microbiota Nazifi S,of Sajedianfardrat exposed to J Radical ranch cadmium and mercury. Veterinary Science Development 5(2). B. coagulans https://bradsplantbased. crunchy probiotic kale 7. Jäger R, Shields KA, Lowery RP, De Souza EO, Partl JM, et al. (2016) Probiotic Bacillus coagulans GBI-30 com/shop/crunchy-kale/ crunchy-kale-radical-ranch- muscle damage and increases recovery. PeerJ 4: e2276. Enjoy GBI-30, 6086 reduces exercise-induced wprobiotics-12-pack/ 8. Majeed M, Nagabhushanam K, Natarajan S, Sivakumar A, Ali F, et B. coagulans https://enjoylifefoods.com/ al. (2016) Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: Enjoy Life Pancake+ a double blind randomized placebo controlled pilot clinical waffle mix GBI-30 our-food/baking-mixes/ study. Nutrition journal 15(1): 21. pancake-waffle-mix/INDIA Nutty delight B.coagulans https://www.probiotaevent. 9. Majeed M, Nagabhushanam K, Sankaran N, Vaidyanathan P, Arumugam museli SNZ 1969 S, et al. (2017) U.S. Patent No. 9,579,352. Washington, DC: U.S. Patent com/wp-content/ uploads/2017/02/Emma- 10. andNyangale Trademark EP, Farmer Office. S, Cash HA, Keller D, Chernoff D et al. (2015) Bacillus Schofield-Probiota-2017.pdfGaneden (USA) coagulans NurtureMe B. coagulans https://nurturme.com/ GBI-30, 6086 modulates Faecalibacteriumprausnitzii in 11. olderPandey men KR, and Naik women. SR, TheVakil Journal BV (2015) of nutrition Probiotics, 145(7): prebiotics 1446-1452. and MayPro (Japan) proDURA B. coagulans http://maypro.com/ synbiotics-a review. Journal of food science and technology 52(12): products/produra#_ednref1 12. 7577-7587.Sudha MR, Yelikar KA, Deshpande S (2012) Clinical Study of

B. coagulans Sabinsa (USA) Patients with Bacterial Vaginosis. Indian journal of microbiology 52(3): Lactospore Bacilluscoagulans Unique IS-2 (ATCC PTA-11748) in the Treatment of MTCC 5856 http://www.lactospore.com/ 396-399.

How to cite this article: Kavita R P. Mini Review on the Dynamic Probiotic-Bacillus coagulans. Dairy and Vet Sci J. 2017; 3(3): 555614 .DOI: 10.19080/ 002 JDVS.2017.03.555613 Journal of Dairy and Veterinary Sciences

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How to cite this article: Kavita R P. Mini Review on the Dynamic Probiotic-Bacillus coagulans. Dairy and Vet Sci J. 2017; 3(3): 555614 .DOI: 10.19080/ 003 JDVS.2017.03.555613