Angel's Trumpets & Thornapples
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4/23/2015 1 •Psychedelics Or Hallucinogens
4/23/2015 Hallucinogens •Psychedelics or This “classic” hallucinogen column The 2 groups below are quite different produce similar effects From the classic hallucinogens Hallucinogens Drugs Stimulating 5HT Receptors Drugs BLOCKING ACH Receptors • aka “psychotomimetics” LSD Nightshade(Datura) Psilocybin Mushrooms Jimsonweed Morning Glory Seeds Atropine Dimethyltryptamine Scopolamine What do the very mixed group of hallucinogens found around the world share in common? •Drugs Resembling NE Drugs BLOCKING Glutamate Receptors •Peyote cactus Phencyclidine (PCP) •Mescaline Ketamine All contain something that resembles a •Methylated amphetamines like MDMA High dose dextromethorphan •Nutmeg neurotransmitter •New synthetic variations (“bath salts”) •5HT-Like Hallucinogens •LSD History • Serotonin • created by Albert Hofmann for Sandoz Pharmaceuticals LSD • was studying vasoconstriction produced by ergot alkaloids LSD • initial exposure was accidental absorption thru skin • so potent ED is in millionths of a gram (25-250 micrograms) & must be delivered on something else (sugar cube, gelatin square, paper) Psilocybin Activate 5HT2 receptors , especially in prefrontal cortex and limbic areas, but is not readily metabolized •Characteristics of LSD & Other “Typical” •Common Effects Hallucinogens • Sensory distortions (color, size, shape, movement), • Autonomic (mostly sympathetic) changes occur first constantly changing (relatively mild) • Vivid closed eye imagery • Sensory/perceptual changes follow • Synesthesia (crossing of senses – e.g. hearing music -
Protabase Record Display Datura Stramonium L
Protabase Record display www.prota.org Datura stramonium L. Protologue Sp. pl. 1: 179 (1753). Family Solanaceae Chromosome number 2n = 24 Vernacular names Thorn apple, green thorn apple, Jimson weed, Jamestown weed, devil’s apple, devil’s trumpet, stramonium (En). Pomme épineuse, stramoine, datura, feuille du diable, herbe du diable (Fr). Figueira do inferno, pomo espinhoso, erva dos bruxos, palha verde, estramonio (Po). Muranha (Sw). Origin and geographic distribution Datura stramonium is native to the Americas and has been introduced in many tropical, subtropical and even temperate regions. It is a naturalized weed in many African countries, but is probably seriously under-reported. Uses Datura stramonium and Datura metel L. have largely similar medicinal uses throughout the world. The most widely known use of Datura stramonium and of other Datura species is for relieving asthma, cough, tuberculosis and bronchitis by smoking the dried leaves, roots or flowers. ‘Asthma cigarettes’ have been shown to be very effective in some cases, but in other cases they had little or no effect. Cigarettes made with the leaves are also used to treat Parkinson’s disease. A decoction or infusion of leaves is given as a sedative to mental and schizophrenic patients. The leaves are applied as a dressing to cure rheumatic pain, swellings, wounds, gout, burns, ingrown toe-nails, fungal infections, tumours and ulcers. Dried pulverized leaves are dusted on wounds or applied after mixing the powder with fat or Vaseline. In DR Congo pounded fresh root and fresh leaves are soaked in water and the liquid is given in enema as an abortifacient. -
Chemical Compounds, Pharmacological and Toxicological Activity of Brugmansia Suaveolens: a Review
plants Review Chemical Compounds, Pharmacological and Toxicological Activity of Brugmansia suaveolens: A Review Vera L. Petricevich 1 , David Osvaldo Salinas-Sánchez 2, Dante Avilés-Montes 3, Cesar Sotelo-Leyva 4 and Rodolfo Abarca-Vargas 1,* 1 Faculty of Medicine, Autonomous University of the State of Morelos (UAEM), Street: Leñeros, esquina Iztaccíhuatl s/n. Col. Volcanes, Cuernavaca 62350, Morelos, Mexico; [email protected] 2 Biodiversity and Conservation Research Center, Autonomous University of the State of Morelos (UAEM), Av. Universidad 1001, Col. Chamilpa, Cuernavaca 62209, Morelos, Mexico; [email protected] 3 Faculty of Biological Science, Autonomous University of the State of Morelos (UAEM), Av. Universidad 1001, Col. Chamilpa, Cuernavaca 62209, Morelos, Mexico; [email protected] 4 Faculty of Chemistry-Biological Sciences, Autonomous University of Guerrero Av. Lázaro Cárdenas s/n, South University City, Chilpancingo 39000, Guerrero, Mexico; [email protected] * Correspondence: [email protected]; Tel.: +52-777-361-2155 Received: 30 July 2020; Accepted: 3 September 2020; Published: 8 September 2020 Abstract: This study investigates updated information in different search engines on the distribution, phytochemistry, pharmacology, and toxicology of Brugmansia suaveolens (Solanaceae) using the extracts or chemical compounds at present. This plant has been used in traditional medicine in different cultures as a hallucinatory, analgesic, aphrodisiac, nematicide, sleep inducer, and muscle relaxant, as well as a treatment for rheumatism, asthma, and inflammation. The flowers, fruits, stems, and roots of the plant are used, and different chemical compounds have been identified, such as alkaloids, volatile compounds (mainly terpenes), coumarins, flavonoids, steroids, and hydrocarbons. The concentration of the different compounds varies according to the biotic and abiotic factors to which the plant is exposed. -
"National List of Vascular Plant Species That Occur in Wetlands: 1996 National Summary."
Intro 1996 National List of Vascular Plant Species That Occur in Wetlands The Fish and Wildlife Service has prepared a National List of Vascular Plant Species That Occur in Wetlands: 1996 National Summary (1996 National List). The 1996 National List is a draft revision of the National List of Plant Species That Occur in Wetlands: 1988 National Summary (Reed 1988) (1988 National List). The 1996 National List is provided to encourage additional public review and comments on the draft regional wetland indicator assignments. The 1996 National List reflects a significant amount of new information that has become available since 1988 on the wetland affinity of vascular plants. This new information has resulted from the extensive use of the 1988 National List in the field by individuals involved in wetland and other resource inventories, wetland identification and delineation, and wetland research. Interim Regional Interagency Review Panel (Regional Panel) changes in indicator status as well as additions and deletions to the 1988 National List were documented in Regional supplements. The National List was originally developed as an appendix to the Classification of Wetlands and Deepwater Habitats of the United States (Cowardin et al.1979) to aid in the consistent application of this classification system for wetlands in the field.. The 1996 National List also was developed to aid in determining the presence of hydrophytic vegetation in the Clean Water Act Section 404 wetland regulatory program and in the implementation of the swampbuster provisions of the Food Security Act. While not required by law or regulation, the Fish and Wildlife Service is making the 1996 National List available for review and comment. -
Marketplace Plants Used in Ceremonial Cleansing Among Andean Qechuans of Ecuador
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Marshall University Marshall University Marshall Digital Scholar Theses, Dissertations and Capstones 2007 Marketplace plants used in ceremonial cleansing among Andean Qechuans of Ecuador Sushma Shrestha Follow this and additional works at: https://mds.marshall.edu/etd Part of the Folklore Commons, Indigenous Studies Commons, and the Social and Cultural Anthropology Commons Recommended Citation Shrestha, Sushma, "Marketplace plants used in ceremonial cleansing among Andean Qechuans of Ecuador" (2007). Theses, Dissertations and Capstones. 1275. https://mds.marshall.edu/etd/1275 This Thesis is brought to you for free and open access by Marshall Digital Scholar. It has been accepted for inclusion in Theses, Dissertations and Capstones by an authorized administrator of Marshall Digital Scholar. For more information, please contact [email protected], [email protected]. Marketplace plants used in ceremonial cleansing among Andean Qechuans of Ecuador Thesis submitted to The Graduate School of Marshall University In partial fulfilment of the Requirements for the degree of Master of Science in Biological Sciences by Sushma Shrestha Dr. Dan K. Evans, Ph.D., Chairperson Dr. Charles Somerville, Ph.D. Dr. Tom Pauley, Ph.D. Marshall University 2007 ii TO MY FAMILY and INDIGINOUS PEOPLE AROUND THE WORLD iii ACKNOWLEDGEMENT I am grateful to Dr. Evans for further igniting my interest in plant and indigenous people. I appreciate all your help in Ecuador and here during the research and beyond with both academic and financial support for the work. You are a wonderful professor, advisor and a travel companion. -
Datura- a Devil Weed Or Angel's Trumpet
Datura- A Devil Weed Or Angel’s Trumpet. Review Article by : Shaheen Bibi Email: [email protected] 1 Datura Inoxia- A Devil weed or Angel’s Trumpet Abstract Datura is a mystery Plant. It belongs to family Solanaceae. There are many important species of genus Datura. Despite of many reports about being toxic, its still debated for its medicinal properties. The genus Datura has a vast history from early time through World War till modern times. Since long time, Datura has been used as a folk medicine in many ancient cultures and even used today. The ethnobotanical information predicts its useful drug value. This plant is well known for its hallucinogenic property. Heiser states that Datura is genus of contrast-from smelly weeds to lovely ornamentals”. 38 Analyzing the chemical profile of Datura , it is reported to be rich in alkaloids. These alkaloids are member of Tropane. Important tropines are Atropine, Scopolamine and Hyoscyamine. The highest in percentage of atropine in D.inoxia is found in its seeds.39 Datura can cause various complications. Some of its effects are systemic. The primary and alarming sign of toxicity with D.inoxia is mydriasis i.e. the change in pupil centration 40,41. Atropine also has the hallucination effect. It blocks the action of acetylcholine at its receptors. Datura inoxia foliage is also harmful for grazing animals or animals that feed on the seeds. Datura inoxia has an anticholinergic property. This property is due to presence of Scopolamine 18. Interestingly, there are beetles and some bees that survive on Datura and they have established certain biochemical mechanisms to defend themselves against the plants intoxicating chemicals. -
Nightshade”—A Hierarchical Classification Approach to T Identification of Hallucinogenic Solanaceae Spp
Talanta 204 (2019) 739–746 Contents lists available at ScienceDirect Talanta journal homepage: www.elsevier.com/locate/talanta Call it a “nightshade”—A hierarchical classification approach to T identification of hallucinogenic Solanaceae spp. using DART-HRMS-derived chemical signatures ∗ Samira Beyramysoltan, Nana-Hawwa Abdul-Rahman, Rabi A. Musah Department of Chemistry, State University of New York at Albany, 1400 Washington Ave, Albany, NY, 12222, USA ARTICLE INFO ABSTRACT Keywords: Plants that produce atropine and scopolamine fall under several genera within the nightshade family. Both Hierarchical classification atropine and scopolamine are used clinically, but they are also important in a forensics context because they are Psychoactive plants abused recreationally for their psychoactive properties. The accurate species attribution of these plants, which Seed species identifiction are related taxonomically, and which all contain the same characteristic biomarkers, is a challenging problem in Metabolome profiling both forensics and horticulture, as the plants are not only mind-altering, but are also important in landscaping as Direct analysis in real time-mass spectrometry ornamentals. Ambient ionization mass spectrometry in combination with a hierarchical classification workflow Chemometrics is shown to enable species identification of these plants. The hierarchical classification simplifies the classifi- cation problem to primarily consider the subset of models that account for the hierarchy taxonomy, instead of having it be based on discrimination between species using a single flat classification model. Accordingly, the seeds of 24 nightshade plant species spanning 5 genera (i.e. Atropa, Brugmansia, Datura, Hyocyamus and Mandragora), were analyzed by direct analysis in real time-high resolution mass spectrometry (DART-HRMS) with minimal sample preparation required. -
The Twenty Greatest Music Concerts I've Ever Seen
THE TWENTY GREATEST MUSIC CONCERTS I'VE EVER SEEN Whew, I'm done. Let me remind everyone how this worked. I would go through my Ipod in that weird Ipod alphabetical order and when I would come upon an artist that I have seen live, I would replay that concert in my head. (BTW, since this segment started I no longer even have an ipod. All my music is on my laptop and phone now.) The number you see at the end of the concert description is the number of times I have seen that artist live. If it was multiple times, I would do my best to describe the one concert that I considered to be their best. If no number appears, it means I only saw that artist once. Mind you, I have seen many artists live that I do not have a song by on my Ipod. That artist is not represented here. So although the final number of concerts I have seen came to 828 concerts (wow, 828!), the number is actually higher. And there are "bar" bands and artists (like LeCompt and Sam Butera, for example) where I have seen them perform hundreds of sets, but I counted those as "one," although I have seen Lecompt in "concert" also. Any show you see with the four stars (****) means they came damn close to being one of the Top Twenty, but they fell just short. So here's the Twenty. Enjoy and thanks so much for all of your input. And don't sue me if I have a date wrong here and there. -
Sinopsis De La Familia Acanthaceae En El Perú
Revista Forestal del Perú, 34 (1): 21 - 40, (2019) ISSN 0556-6592 (Versión impresa) / ISSN 2523-1855 (Versión electrónica) © Facultad de Ciencias Forestales, Universidad Nacional Agraria La Molina, Lima-Perú DOI: http://dx.doi.org/10.21704/rfp.v34i1.1282 Sinopsis de la familia Acanthaceae en el Perú A synopsis of the family Acanthaceae in Peru Rosa M. Villanueva-Espinoza1, * y Florangel M. Condo1 Recibido: 03 marzo 2019 | Aceptado: 28 abril 2019 | Publicado en línea: 30 junio 2019 Citación: Villanueva-Espinoza, RM; Condo, FM. 2019. Sinopsis de la familia Acanthaceae en el Perú. Revista Forestal del Perú 34(1): 21-40. DOI: http://dx.doi.org/10.21704/rfp.v34i1.1282 Resumen La familia Acanthaceae en el Perú solo ha sido revisada por Brako y Zarucchi en 1993, desde en- tonces, se ha generado nueva información sobre esta familia. El presente trabajo es una sinopsis de la familia Acanthaceae donde cuatro subfamilias (incluyendo Avicennioideae) y 38 géneros son reconocidos. El tratamiento de cada género incluye su distribución geográfica, número de especies, endemismo y carácteres diagnósticos. Un total de ocho nombres (Juruasia Lindau, Lo phostachys Pohl, Teliostachya Nees, Streblacanthus Kuntze, Blechum P. Browne, Habracanthus Nees, Cylindrosolenium Lindau, Hansteinia Oerst.) son subordinados como sinónimos y, tres especies endémicas son adicionadas para el país. Palabras clave: Acanthaceae, actualización, morfología, Perú, taxonomía Abstract The family Acanthaceae in Peru has just been reviewed by Brako and Zarruchi in 1993, since then, new information about this family has been generated. The present work is a synopsis of family Acanthaceae where four subfamilies (includying Avicennioideae) and 38 genera are recognized. -
Trap Pilates POPUP
TRAP PILATES …Everything is Love "The Carters" June 2018 POP UP… Shhh I Do Trap Pilates DeJa- Vu INTR0 Beyonce & JayZ SUMMER Roll Ups….( Pelvic Curl | HipLifts) (Shoulder Bridge | Leg Lifts) The Carters APESHIT On Back..arms above head...lift up lifting right leg up lower slowly then lift left leg..alternating SLOWLY The Carters Into (ROWING) Fingers laced together going Side to Side then arms to ceiling REPEAT BOSS Scissors into Circles The Carters 713 Starting w/ Plank on hands…knee taps then lift booty & then Inhale all the way forward to your tippy toes The Carters exhale booty toward the ceiling….then keep booty up…TWERK shake booty Drunk in Love Lit & Wasted Beyonce & Jayz Crazy in Love Hands behind head...Lift Shoulders extend legs out and back into crunches then to the ceiling into Beyonce & JayZ crunches BLACK EFFECT Double Leg lifts The Carters FRIENDS Plank dips The Carters Top Off U Dance Jay Z, Beyonce, Future, DJ Khalid Upgrade You Squats....($$$MOVES) Beyonce & Jay-Z Legs apart feet plie out back straight squat down and up then pulses then lift and hold then lower lift heel one at a time then into frogy jumps keeping legs wide and touch floor with hands and jump back to top NICE DJ Bow into Legs Plie out Heel Raises The Carters 03'Bonnie & Clyde On all 4 toes (Push Up Prep Position) into Shoulder U Dance Beyonce & JayZ Repeat HEARD ABOUT US On Back then bend knees feet into mat...Hip lifts keeping booty off the mat..into doubles The Cartersl then walk feet ..out out in in.. -
Drugs That Can Cause Delirium (Anticholinergic / Toxic Metabolites)
Drugs that can Cause Delirium (anticholinergic / toxic metabolites) Deliriants (drugs causing delirium) Prescription drugs . Central acting agents – Sedative hypnotics (e.g., benzodiazepines) – Anticonvulsants (e.g., barbiturates) – Antiparkinsonian agents (e.g., benztropine, trihexyphenidyl) . Analgesics – Narcotics (NB. meperidine*) – Non-steroidal anti-inflammatory drugs* . Antihistamines (first generation, e.g., hydroxyzine) . Gastrointestinal agents – Antispasmodics – H2-blockers* . Antinauseants – Scopolamine – Dimenhydrinate . Antibiotics – Fluoroquinolones* . Psychotropic medications – Tricyclic antidepressants – Lithium* . Cardiac medications – Antiarrhythmics – Digitalis* – Antihypertensives (b-blockers, methyldopa) . Miscellaneous – Skeletal muscle relaxants – Steroids Over the counter medications and complementary/alternative medications . Antihistamines (NB. first generation) – diphenhydramine, chlorpheniramine). Antinauseants – dimenhydrinate, scopolamine . Liquid medications containing alcohol . Mandrake . Henbane . Jimson weed . Atropa belladonna extract * Requires adjustment in renal impairment. From: K Alagiakrishnan, C A Wiens. (2004). An approach to drug induced delirium in the elderly. Postgrad Med J, 80, 388–393. Delirium in the Older Person: A Medical Emergency. Island Health www.viha.ca/mhas/resources/delirium/ Drugs that can cause delirium. Reviewed: 8-2014 Some commonly used medications with moderate to high anticholinergic properties and alternative suggestions Type of medication Alternatives with less deliriogenic -
Chemical Composition of the Seeds of Datura Innoxia
IJISET - International Journal of Innovative Science, Engineering & Technology, Vol. 3 Issue 2, February 2016. www.ijiset.com ISSN 2348 – 7968 Chemical composition of the seeds of Datura innoxia 1 2 1 2 Kendeson Anawuese ChristianaP ,P Iloka Gabriel SundayP ,P Bulama Joshua SamailaP P andP P Dashak Albert DayilP .P 1 2 P DepartmentP of Chemical Sciences, Federal University Kashere, P.M.B 0182, Gombe, Nigeria. P DepartmentP of Chemistry, University of Jos, P.M.B 2084, Jos, Nigeria. Correspondence Author: [email protected] Abstract The elemental analysis carried out on the seeds of the plant Datura innoxia showed the presence of phosphorus, nitrogen and chlorine. The moisture content was determined and found to be 6.61% ± 0.16. The ash content was 3.08% ± 0.13. The total carbohydrate and reducing sugar contents were determined and found to be 25.07% ± 0.88 and 21.69% ± 1.11 respectively. The lignin content was found to be 5.58% ± 0.16 while the crude fibre content was determined to be 42.42% ± 0.02. The percentage crude protein was found to be 8.64% ± 0.05, and the nitrogen content was determined to be 1.52% ±0.01. The non-polar and polar fat contents were found to be 18.24% ± 0.33 and 23.51% ± 0.25 respectively. The mineral composition of the Datura innoxia was determined and found to contain Ca, Mg, K, Na, Cu, Zn, Mn, Fe, Ni, Cd and Pb. The K, Mg and Ca contents were found to be 3450, 2500, and 2000 mg/100g respectively.