Zakon, H.H. 1

CURRICULUM VITAE

Harold H. Zakon Section of Neurobiology phone: (512)-471-0194, -3440 The University of Texas fax: (512)-471-9651 Austin, TX 78712 E-mail: [email protected]

EDUCATION 1981-1983: Postdoctoral fellow, Scripps Institution of Oceanography, University of California, San Diego, Lab. of Dr. T.H. Bullock. 1974-1981: Ph.D. in Neurobiology and Behavior, Cornell University, Ithaca, NY. 1968-1972: B. S. with High Honors, Marlboro College, Marlboro, VT.

PROFESSIONAL EXPERIENCE 2001-- Adjunct Professor, Marine Biological Laboratory, Woods Hole, MA. 1999-2006 Chairman, Section of Neurobiology, The University of Texas at Austin. 1998-- Professor, Section of Neurobiology, The University of Texas, Austin. 1994-1998 Professor, Dept. of Zoology, The University of Texas, Austin. 1988-1993: Assoc. Professor, Dept. of Zoology, The University of Texas, Austin. 1983-1988: Assist. Professor, Dept. of Zoology, The University of Texas, Austin. 1981-1983: Postdoctoral fellow at The University of California, San Diego, Calif. 1974-1981: Teaching and Research Assist., Graduate Program at Cornell. 1972-1974: Research Assist., Dept. Psychiatric Research, Harvard Medical School, Cambridge, MA.

PROFESSIONAL SOCIETIES Society for Neuroscience; International Society for Neuroethology; Association for Research in Otolaryngology; American Association for the Advancement of Science; International Brain Research Organization, Society for Behavioral Neuroendocrinology.

PROFESSIONAL SERVICE Reviewer for: Behavior; Brain, Behavior & Evolution; Brain Research; Comparative Physiology & Biochemistry; BMC Neuroscience; Current Biology; General & Comparative Endocrinology; FEBS Letters; Genes, Brain & Behavior; Hearing Research; Hormones and Behavior; J. Biological Chemistry.; J. Comparative Neurology; J. Comparative Physiology A; J. Experimental Biology; J. Molecular Evolution; J. Neurobiology; J. Neurophysiology; J. Neuroscience; Molecular Biology & Evolution; Nature; Nature Neuroscience; Naturwissenschaften; Neuroscience Letters; PLoS Biology; Proceedings of the National Academy of Sciences USA.; Science; Trends in Neurosciences.

Ad Hoc reviewer for N.I.H., N.I.M.H., N.S.F., and N.S.E.R.C. (Canadian). Hearing Research Study Section member (1995- 1999); Genetic Variation and Evolution Study Section member (2009-). Co-director of "Neural Systems and Behavior" Course at the Marine Biological Laboratory at Woods Hole, MA (1995- 1999). Faculty member (2000-2001). Editorial Board of J. Comparative Physiology A (1996--); Hormones & Behavior (2001--2008); Brain, Beavhior & Evolution (2009-). Council member, International Society for Neuroethology Co-Vice Chairman for the first Gordon Conference on Neuroethology (1999), Chairman for second GRC on Neuroethology (2002). Judge in the Siemens-Westinghouse Science Competition, Austin Texas (1999) Co-Chairman, International Society for Neuroethology World Congress (2010) Zakon, H.H. 2

AWARDS ANDS HONORS

2009 Laura & Arther Colwin Fellowship at the Marine Biological Laboratory 2007 Laura & Arther Colwin Fellowship at the Marine Biological Laboratory 2005 Keynote Speaker, Society for Behavioral Neuroendocrinology Annual meeting, Austin , TX; Keynote Speaker for “ Workshop” Ottawa, Canada. 2001 Keynote Speaker, Annual Neuroscience Program. U. Mass, Amherst (see below). 2000 Awarded the University of Texas’ President's Associate's Teaching Excellence Award. 1998 Nominated for Chancellor's Council Outstanding Teaching Award; Distinguished Lecturer, Lousiana State University, Baton Rouge; ISN Young Investigator Award to G. Troy Smith, a postdoctoral fellow in my laboratory. 1997 Capranica Foundation Award for most significant paper in Neuroethology to Michael Ferrari, a graduate student in my laboratory. 1996 Alberta Heritage Foundation Visiting Lecturer, Alberta Canada. 1987 Research Career Development Award (NIH). 1982 Travel grant from the International Brain Research Organization to present a paper at its first world congress in Lausanne, Switzerland. 1981 Best student paper award in Developmental Biology at ASZ meetings in Seattle. 1981 Awarded travel grant by the American Society of Zoologists to attend meeting in Seattle and present a paper in the "Pattern Formation" contributed paper session. 1981 National Institutes of Health Postdoctoral Fellowship. 1980 National Science Foundation Postdoctoral Fellowship. 1980 North Atlantic Treaty Organization (NATO) Postdoctoral Fellowship (declined).

INVITED LECTURES IN SYMPOSIA 2011 Florida State University (pending) 2010 International School of Neuroethology, Buenos Aires, Argentina. 2009 Janelia Conference: Neural Circuits Controlling Sexual Behavior, Janelia Farm, VA (pending). 2007 Heiligenberg Symposium, University of California, San Diego; Symposium for retirement of Curt Bell, Oregon Health Sciences Center, Portland, OR.; Symposium on “Neurosensory Ecology“ Tuscany, Italy; Symposium on “New Perspectives on Fish Neurobiology: Evolution, Development, and Function” Shanghai, China. 2006 Symposium on “Design, molecular basis, and evolution of muscles for different activities.“ American Physiological Society conference “Comparative Physiology 2006: integrating diversity”, Virginia Beach, VA. 2004 Symposium on “Orchestration of Behavior by Neuromodulators” International Society for Neuroethology, Nyborg, Denmark. 2003 Third Neural Coding Workshop, The University of Chicago. 2001 Symposium on “Comparative Neuroendocrinology: cellular and molecular approaches.” in the Society for Behavioral Neuroendocrinology, Scottsdale, AZ.; Plenary Speaker for Northwest Developmental Biology meeting, Friday Harbor; Karger Workshop at the J.B. Johnston Club, “Convergence in Evolution of the Nervous System.” ; symposium on “Electroreception” Bonn, Germany ; Keynote Speaker “Neuroscience and Behavior Program” annual banquet, University of Massachusetts at Amherst. 1998 Symposium "Electroreception and Electrocommunication" San Diego, CA.; symposium on "Life Span Actions of Developmental Hormones" at the Society for Behavioral Neuroendocrinology, Atlanta, GA; Karger Workshop at the J. B. Johnston Club "Steroid Hormones and the Brain" Society for Neuroscience meeting, Los Angeles. Zakon, H.H. 3

1995 Symposium on "Behavior" in the International Symposium on Reproductive Physiology of Fish" in Austin, TX. 1993 Presidential Symposium on “Sensory Transduction” Association for Research in Otolaryngology, St. Petersburg, Florida; Symposium on “Hormones and Behavior” and Keynote Address, Midwestern Chapter of the Society for Neuroscience, Chicago, IL; Joint U.S.-Russian meeting on Sensory Biology, College Park, MD.; Symposium on "Repair and Regeneration in the Inner Ear" Hearing Research Trust, Wye College, England; Organized symposium on "Steroid Action and Excitable Cells" at Soc. for Neurosci. Meetings, Wash. D.C. 1992 Symposium on “Electrobiochemistry” at the Gordon Conference, Tilton, N.H.; Symposium on “Regeneration of Sensory Receptors.” at the Society for Neuroscience Meetings, Anaheim, CA; Symposium on “The Neurobiology of Reproduction.” J.B. Johnston Club, Anaheim, CA. 1991 Symposium on “GnRH Pulse Generation” sponsored by the National Institutes of Health, Bethesda, MD. 1990 Symposium on "Neuroendocrine Strategies in a Tropical Environment" American Society of Zoologists, San Antonio, TX; Symposium on "Regeneration of Vertebrate Sensory Receptors" CIBA Foundation, London, England. 1989 Symposium on "The Neurobiology of Weakly Electric Fish." Gif-sur-Yvette, France; Symposium on "Hormones, Neural circuits and Communication." Society for Neuroscience meetings in November 1989, Phoenix, AZ. 1986 Symposium on "Biology of Change in Otolaryngology: Developmental Biology, Plasticity and Compensation, and Injury and Repair Mechanisms." Association for Research in Otolaryngology, Tampa, Florida; International Meeting on "The Amphibian Auditory System." Bielefeld, Germany. 1985 International Meeting on "Sensory Biology of Aquatic ," Sarasota, Florida sponsored by ONR; Organizer and Chairman for session on "Sensory-neural development" at the Larval Fish Conference, Marine Sciences Institute, Port Aransas, Texas; Co-organizer (w/ G. Pollak, W. Wilczynski) for Symposium "Common Principles in the Neuroethology of Acoustic and Electric Communication." An inaugural meeting of the International Society for Neuroethology, at University of Texas, Austin, TX. 1984 Cajal Club, annual meeting of the American Association of Anatomists, Seattle, Wash. 1983 J.B. Johnston Club, annual meeting of the Society for Neuroscience, Boston, Mass.

INVITED LECTURES AT VARIOUS INSTITUTIONS 2010 Clemente Estable Institute, Montevideo, Uruguay; SUNY Stony Brook, NY; ; University of Arizona (pending). 2009 University of California, Davis; Washington University, St. Louis; Oberlin College (pending); Case Western Reserve (pending). 2008 McGill University; University of Oregon; Oregon State University. 2007 University of Texas Marine Sciences Institute, Port Aransas, TX; Institute of Zoology, Beijing, China. 2006 Georgia State University, Atlanta, GA.; University of Texas, San Antonio; Universidad San Francisco de Quito, Quito, Ecuador. 2005 University of Pennsylvania; University of Virginia; Albert Einstein College of Medicine. 2004 Texas A&M, College Station; Texas A&M, Kingsville; Hunter College, New York; City College of New York; University of Illinois, Urbana-Champaign. 2003 Columbia University; University of Texas, Galveston. 2002 Michigan State University; University of Oklahoma, Norman, OK; Johns Hopkins University; University of Maryland. Zakon, H.H. 4

2001 California Institute of Technology, Pasadena, CA; University of Arkansas, Fayetteville; University of California at Davis; University of Washington, Seattle; Harvard University; University of Massachusetts, Amherst. 2000 University of Illinois, Chicago; Northwestern University, Evanston, IL; University of Chicago, Chicago, IL.; New Mexico State University, Las Cruces, NM. 1999 Baylor University, Houston, TX; Cornell University, Ithaca, N.Y.; University College, London, England. 1998 University of California, Los Angeles; University of Southern California; University of Washington, Seattle; Texas Women's University, Denton, TX; Harvard Medical School, Boston, MA; Lousiana State University, Baton Rouge, LA; Florida International University, Miami. 1997 University of Connecticut, Storrs; Marine Biological Laboratory, Woods Hole, MA. 1996 University of Lethbridge, Canada; University of Calgary, Canada; University of Oregon Health Sci. Ctr., Portland; University of Virginia, Charlottesville; University of Cincinnati; University of Texas at San Antonio. 1995 University of Tennessee, Knoxville; Baylor University, Dallas, TX. 1994 University of Texas at Galveston; Baylor University; University of Oregon at Eugene; University of Pennsylvaina, Philadelphia, PA.; University of North Texas, Denton, TX; Marine Biological Laboratory, Woods Hole, MA. 1993 University of Indiana, Bloomington; Union College, Schenectady, N.Y.; University of Virginia, Charlottesville, VA. 1992 University of Washington, Seattle; University of California at San Diego, La Jolla. 1991 Univ. of Utah; University of Pittsburgh; Brown University; Massachusetts Institute of Technology; University of Colorado at Boulder; University of Colorado Medical School, Denver; Colorado State University, Fort Collins; Harvard University. 1990 Univ. of Maryland; Cambridge University, Cambridge, England. 1989 Texas A&M; Univ. of Oklahoma; American Museum of Natural History, N.Y.; Columbia University, N.Y.; University of Northern Arizona; University of Arizona. 1988 Northwestern Univ.; Univ. of Illinois Chicago Circle; University of Rochester, Rochester, N.Y.; Cornell University. 1987 U.T. Houston; Portland State University, Oregon; University of Oregon, Eugene, OR; University of Missouri, Columbia, Mo. 1986 CNRS, Gif-sur-Yvette, France; Boston University; Massachusetts Institute of Technology; Rockefeller University; University of Texas at Galveston; Marlboro College, Vermont. 1984 Rice University. 1983 Cambridge University, Cambridge, England; Universität Konstanz, Germany; CNRS, Gif- sur-Yvette, France. 1982 Cornell University; University of California at Los Angeles. 1981 The University of Illinois at Champaign-Urbana; The University of Connecticut at Storrs, CT.

RESEARCH SUPPORT My laboratory has been supported continuously since 1983 mainly by the National Institutes of Health, and the National Science Foundation I have also had funding from the Office of Naval Research, Department of the Army, and the Texas Advanced Research Program.

Current Support: “Evolution of sodium channel genes” (NIH 5R01GM084879-02). “Evolution of resistance to scorpion venoms: a comparative genomic approach.” (DoD W911NF-06-1-0213).

Zakon, H.H. 5

University and Departmental Service I have served on a number of University-level committees including: The Dean's committee on Matching Funds in the College of Natural Sciences; Committee for Minority Affairs in the College of Natural Sciences; Danforth-Compton Minority Fellowship Selection Committee; Co-Chair, Search Committee for Director of the Marine Sciences Institute; College Curriculum Committee; Institutional Animal Care and Use Committee. I was Chairman of the Section of Neurobiology from 1999-2006.

I served on many Zoology departmental committees including: chairman of faculty search committees, the department's long-range planning committee, senior professor salary committee, and tenure review committees. I was also the Assistant Graduate Advisor. Most recently, I was chairman of the Section of Neurobiology from 1999-2006.

I serve on the dissertation committees of many graduate students, including some in other institutions (UT Galveston; UT San Antonio). I have been a co-dissertation advisor (co- orientadór) for a student at the Universidad de Republica, Montivideo Uruguay.

Teaching My main undergraduate teaching has been a large (~150 students) upper division course Vertebrate Physiology (ZOO 365R) which I often co-teach with Dr. George Pollak. I also teach undergraduates in individual instruction courses virtually every semester. In addition, I have taught a number of graduate seminars alone or with colleagues Animal Communication with Dr. Michael Ryan, Functional Neuroanatomy with Dr. Walter Wilczynski, Developmental Neurobiology with Dr. Wesley Thompson, and Hormones and the Brain which I teach alone. I have also given guest lectures in a number of courses on campus. I co-teach with Dr. John Mihic Principles of Neuroscience (BIO382T) an introductory course for all first year graduate students in the Neuroscience program.

Graduate Advising I have had 11 graduate students and 9 postdoctoral fellows previously. I currently have 3 graduate students and 3 postdoctoral associate in my laboratory. In addition, I have served on over 50 Ph.D. committees from students in Zoology, Psychology, Human Ecology, Engineering, and Neuroscience. And have been outside members of committees at UT San Antonio and Instituto Clemente Estable, Montivideo, Uruguay.

PUBLICATIONS 1) Johnston, R., D. Zahorik, K. Immler, H. Zakon (1978) Alteration of male sexual behavior by learned aversions to hamster vaginal secretion. J. Comp. and Physiol. Psych. 92: 85-93. 2) Zakon, H. and R.R. Capranica (1981) An anatomical and physiological study of regeneration of the eighth nerve in the leopard frog. Brain Res. 209: 325-338. 3) Zakon, H. and R.R. Capranica (1981) Reformation of organized connections in the auditory system after regeneration of the eighth nerve. Science 213: 242-244. 4) Wilczynski, W. and H. Zakon (1982) Transcellular transfer of HRP in the amphibian visual system. Brain Res. 239: 29-40. 5) Meyer, J.H. and H.H. Zakon (1982) Androgens alter the tuning of electroreceptors. Science 217: 635- 637. 6) Zakon, H.H. (1983) Reorganization of connectivity in the amphibian central auditory system following VIIIth nerve regeneration: time course. J. Neurophysiol. 49: 1410-1427. Zakon, H.H. 6

7) Zakon, H.H. and J.H. Meyer (1983) Plasticity of electroreceptor tuning in the weakly electric fish, Sternopygus dariensis. J. Comp. Physiol. A 153: 477-487. 8) Meyer, J.H., H. H. Zakon, W. Heiligenberg (1984) Steroid influences upon the electrosensory system of weakly electric fish: direct effects upon discharge frequencies with indirect effects upon electroreceptor tuning. J. Comp. Physiol. A 154: 625-631. 9) Zakon, H.H. (1984) Postembryonic changes in the peripheral electrosensory system of a weakly electric fish: addition of receptor organs with age. J. Comp. Neurol. 228: 557-570. 10) Wilczynski, W., H.H. Zakon and E.A. Brenowitz (1984) Acoustic communication in spring peepers: call characteristics and neurophysiological aspects. J. Comp. Physiol. 155: 577-584. 11) Brenowitz, E.A., W. Wilczynski, and H.H. Zakon (1984) Acoustic communication in spring peepers: environmental and behavioral aspects. J. Comp. Physiol. A 155: 585-592. 12) Keller, C., H.H. Zakon, and D.Y. Sanchez (1986) Evidence for a direct effect of androgens upon electroreceptor tuning. J. Comp. Physiol. A 158: 301-310. 13) Zakon, H.H. (1986) Emergence of tuning in newly-generated tuberous electroreceptors. J. Neurosci. 6: 3297-3308. 14) Zakon, H.H. (l986) The Electroreceptive Periphery. in: Electroreception, T.H. Bullock and W. Heiligenberg, (Eds.), John Wiley Inc., N.Y., pp 103-156. 15) Wilczynski, W., H.H. Zakon, and G.D. Pollak (Editors) (1986) Common Principles in the Neuroethology of Acoustic and Electric Communication. Symposium Proceedings published in Brain, Behavior and Evolution. 28, 156 pp. 16) Zakon, H.H. (1987) Regeneration and Recovery of Function in the Amphibian Auditory System. in: Biology of Change in Otolaryngology: Developmental Biology, Plasticity and Compensation, and Injury and Repair Mechanisms. Ruben, R. and Van de Water, T. (Eds.) Elsevier Press, Amsterdam. pp 305-317. 17) Mills, A. and H.H. Zakon (1987) Coordination of EOD frequency and pulse duration in a weakly electric wave fish: the influence of androgens. J. Comp. Physiol. A 161: 417-430. 18) Zakon, H.H. (1987) Variation in the mode of receptor cell addition in the electrosensory system of gymnotiform fishes. J. Comp. Neurol. 262: 195-214. 19) Zakon, H.H. (1987) Hormone-mediated Plasticity In the Electrosensory System of Weakly Electric Fish. Trends in Neuroscience 10: 416-421. 20) Zakon, H.H. (1988) Electroreceptors: diversity in structure and function. in: Sensory Systems of Aquatic Animals. A.N. Popper, R.R. Fay, J. Atema, W.N. Tavolga (Eds). Springer-Verlag, New York. pp. 813-850. 21) Zakon, H.H. and W. Wilczynski (1988) The Physiology of the Anuran VIIIth Nerve. in: The Amphibian Auditory System, B. Fritzsch, W. Wolkowiak, M.J. Ryan, W. Wilczynski, T. Hetherington (Eds.) pp. 125-155. 22) Zakon, H.H. (1988) Regeneration of the Amphibian Auditory System. in: The Amphibian Auditory System, B. Fritzsch, W. Walkowiak, M.J. Ryan, W. Wilczynski, T. Hetherington (Eds.) pp. 393-411. 23) Lannoo, M.J., L.Maler and H. H. Zakon (1989) Nerve branch-independent somatotopy in the primary afferent projection of weakly electric teleosts (Gymnotifornes). Neuroscience Letters 97: 11-17. 24) Fritzsch, B. and H.H. Zakon (1989) A simple, reliable and inexpensive silver stain for nerve fibers in bleached skin. Zeitschrift für Naturforschung 43: 606-. 25) Ferrari, M. and H.H. Zakon (1989) The tuning of electroreceptors is independent of the activity of the pacemaker nucleus. J. Neuroscience 9: 1354-1361. 26) Bell, C.C., H. H. Zakon and T. Finger (1989) Studies on mormyromast electroreceptor organs and their afferents in mormyrid fish: I. Morphology. J. Comp. Neurol. 186: 391-407. 27) Sanchez, D.Y. and H.H. Zakon (1990) The effects of postembryonic cell addition on the response properties of electroreceptive afferents. J. Neuroscience 10: 361-369. 28) Zakon, H.H., H.-Y. Yan and P. Thomas (1990) Human chorionic gonadotropin-induced shifts in the electrosensory system of the weakly electric fish, Sternopygus. J. Neurobiology 21: 826-833. Zakon, H.H. 7

29) Fritzsch, B., H.H. Zakon and D. Y. Sanchez (1990) The time course of structural changes in regenerating electroreceptors of a weakly electric fish. J. Comp. Neurol. 300: 386-404. 30) Mills, A. C. and H.H. Zakon (1991) Chronic androgen treatment increases action potential duration in the electric organ of Sternopygus. J. Neuroscience 11(8): 2349-2361. 31) Zakon, H.H. (1991) Regeneration of electroreceptors in weakly electric fish in: Regeneration of Vertebrate Sensory Receptor Cells E. Rubel, (Ed.), Wiley Chichester, (CIBA Foundation symposium 160), pp. 294-313. 32) Zakon, H.H., Thomas, P. and Yan, H.-Y. (1991) Electric organ discharge frequency and plasma sex steroid levels during gonadal recrudescence in a natural population of the weakly electric fish Sternopygus macrurus. J. Comp. Physiol. A 169: 493-499. 33) Zakon, H.H., A.C. Mills and M. Ferrari (1991) Androgen-modulation of the electrical activity of the electrosensory system of a weakly electric fish. Seminars in the Neurosciences. 3: 449-457. 34) Fleishman, L., Lemon, W., and H.H. Zakon (1992) Communication in the weakly electric fish Sternopygus macrurus. II. Behavioral test of conspecific EOD detection ability. J. Comp. Physiol. A, 170: 349-356. 35) Mills, A.C., H.H. Zakon, Marchaterre, M.A. and A.H. Bass (1992) Electric organ morphology of Sternopygus macrurus, a wave-type, weakly electric fish with a sexually dimorphic EOD. J. Neurobiol. 23: 920-932. 36) Patterson, J. and Zakon, H.H. (1993) Bromodeoxyuridine labeling reveals satellite-like cells in the electric organ. J. Neurobiology 24: 660-674. 37) Ferrari, M.B. and Zakon, H.H. (1993) Conductances contributing to the action potential of Sternopygus electrocytes. J. Comp. Physiol. A 173: 281-292. 38) Zakon, H.H. (1993) Weakly electric fish as model systems for studying long-term steroid action on neural circuits. Brain, Behav. and Evol. 42: 242-251. 39) Zakon, H.H. (1994) Techniques for recording from electric organs. in Biochemistry and Molecular Biology of Fishes, Vol. III (Ed.) T. Mommsen and P. Hochachka, Elsevier chapter 9: pp. 93-106. 40) Weisleder, P., Lu, Y., and Zakon, H.H. (1994) Effects of denervation upon receptor cell survival and basal cell proliferation in tuberous electroreceptor organs of a weakly electric fish. J. Comp. Neurol. 347: 545-552. 41) Zakon, H.H. (1995) Electric organs: structure, physiology, hormone-sensitivity, and biochemistry. Biochemistry and Molecular Biology of Fishes, Vol. IV (Ed.) T. Mommsen and P. Hochachka, Elsevier chapter 11: pp. 259-277. 42) Ferrari, M.B., McAnelly, L.M. and Zakon, H.H. (1995) Individual variation in and androgen- modulation of the sodium current in electric organ. J. Neuroscience 15: 4023-4032. 43) Weisleder, P. and Zakon, H.H. (1996) Tuberous electroreceptor organs form in denervated regenerating skin of a weakly electric fish. J. Comp. Neurol. 376: 563-574. 44) Schaefer, J.E. and Zakon, H.H. (1996) Opposing actions of androgen and estrogen on in vitro firing frequency of neuronal oscillators in the electromotor system. J. Neuroscience 16: 2860-2868. 45) Patterson, J.M. and Zakon, H.H. (1996) Differential expression of proteins in muscle and electric organ, a muscle derivative. J. Comp. Neurol. 370: 367-376. 46) Zakon, H.H. (1996) Hormonal modulation of communication signals in electric fish. Devel. Neurosci. 18: 115-123. 47) McAnelly, L. and Zakon, H.H. (1996) Protein kinase A activation increases sodium current magnitude in the electric organ of Sternopygus. J. Neuroscience 16: 4383-4388. 48) Dunlap, K., McAnelly. L.M., and Zakon, H.H. (1997) Estrogen modifies an electrocommunication signal by altering the electrocyte sodium current in an electric fish, Sternopygus. J. of Neurosci. 17: 2869-2875. 49) Patterson, J.M. and Zakon, H.H. (1997) Transdifferentiation of muscle to electric organ: regulation of muscle-specific proteins is independent of patterned nerve activity. Dev. Biol. 186: 115-126. 50) Zakon, H.H. (1998) Effects of steroid hormones on electrical activity of excitable cells. Trends in Neurosciences 21: 202-207. Zakon, H.H. 8

51) Unguez, G.A, and Zakon, H.H. (1998) Phenotypic conversion of distinct muscle fiber populations to electrocytes in a weakly electric fish. J. Comp. Neurol. 399: 20-34. 52) Dunlap, K. and Zakon, H. (1998) Hormones and reproductive communication signals in fish. Encyclopedia of Reproduction. Editors-in-Chief, E. Knobil and J.D. Neil. Academic Press, vol. 2, pp. 64-71. 53) Zakon, H.H., Lu, Y. and Weisleder, P. (1998) Sensory cells determine afferent terminal morphology in cross-innervated electroreceptor organs: implications for hair cells. J. Neurosci. 18: 2581-2591. 54) Dunlap, K., Thomas, P., Zakon, H.H. (1998) Diversity of sexual dimorphism in electrocommunication signals and its androgen regulation in a genus of electric fish, . J. Comp. Physiol A 183: 77-86. 55) Zakon, H.H., Gustavson, S. and Prins, G. (1998) Distribution of androgen receptors in the brain, electric organ and electroreceptors of the weakly electric fish, Sternopygus. J. Comp. Neurol. (in press). 56) Dunlap, K.D. and Zakon, H.H. (1998) Behavioral actions of androgens and androgen receptor expression in the electrocommunication system of an electric fish, Eigenmannia virescens. Hormones and Behavior 34: 30-38. 57) Unguez, G.A. and Zakon, H.H. (1998) Re-expression of myogenic proteins in mature electric organ following removal of neural input. J. Neuroscience 18: 9924-9935. 58) Zakon, H.H. and Unguez, G.A. (1999) Development and regeneration of the electric organ. J. Exp. Biol. 202: 1427-1434. 59) Zakon, H.H., McAnelly, M.L., Smith, G.T., Dunlap, K., Lopreato, G., Oestreich, J., Few, W.P. (1999) Plasticity of the electric organ discharge: implications for the regulation of ionic currents. J. Exp. Biol. 202: 1409-1416. 60) Zakon, H.H. and Dunlap, K.D. (1999) Sex hormones and communication signals: a tale of two . Brain, Behavior, and Evolution 54: 61-69. 61) Zakon, H.H. (2000) Sex Steroids and Weakly Electric Fish: A model system for Activational Mechanisms of Hormone Action. In:.Sexual Differentiation of the Brain (Ed) A. Matsumoto, CRC Press pp. 95-112. 62) Smith, G.T. and Zakon, H.H. (2000) Pharmacological characterization of ionic currents that regulate the rhythm of the medullary pacemaker nucleus in a weakly electric fish. J. Neurbiol 42: 270-286. 63) McAnelly, ML Zakon, HH (2000) Co-regulation of voltage-dependent kinetics of Na+ and K+ currents. J. Neurosci. 20: 3408-3414. 64) Smith, GT, Lu, Y, Zakon, HH (2000) Parvocells: A novel interneuron type in the pacemaker nucleus of a weakly electric fish. J. Comp. Neurol. 423: 427-439. 65) Few, WP, Zakon, HH (2001) Local action of androgens and androgen receptor expression in the electric organ of a weakly electric fish. Hormones & Behavior, 40: 434-442. 66) Lopreato, G., Lu, Y., Southwell, A., Atkinson, N., Hillis, D., Wilcox, T. and Zakon, HH (2001) Evolution and divergence of Na+ channel genes in vertebrates. Proceedings of the National Academy of Sciences 98: 7588-7592. 67) Zakon, HH, Smith, GT (2002) Hormones, behavior, and electric fish. in Hormones, Brain and Behavior, (Eds.) D.Pfaff, A.Arnold, A.Etgen, S. Fahrbach, and R. Rubin, Academic Press, pp. 349- 374. 68) Triefenbach, FA, Zakon HH (2002) Signaling responses to sexual and reproductive status cues in the weakly electric fish, Apteronotus leptorhynchus. Animal Behaviour 65: 19-28. 69) Oestreich, J, Zakon, HH (2002) The long-term resetting of a brainstem pacemaker nucleus by synaptic input: a model for sensorimotor adaptation. J. Neurosci. 22(18): 8287-8296. 70) Zakon, HH (2002) Convergence on the molecular level. Brain, Behavior and Evolution. 59: 250-261. 71) Tallarovic, SK and Zakon, HH (2002) Electrocommunication signals in female brown ghost electric knifefish, Apteronotus leptorhynchus. J Comp Physiol A 188: 649-657 Zakon, H.H. 9

72) Unguez, GA and Zakon, HH (2002) Skeletal muscle transformation into electric organ in S. macrurus depends on innervation. J. Neurobiology 53: 391-402. 73) McAnelly, L, Silva, A. and Zakon, HH (2003) Cyclic AMP modulates electrical signaling in a weakly electric fish. J. Comp. Physiol. A 189: 273-282. 74) Zakon, HH (2003) Insights into the mechanisms of neuronal processing from electric fish. Current Opinions in Neurobiology 13: 744-750. 75) Tallarovic, S and Zakon, HH (2005) Electric organ discharge frequency jamming during social interactions in brown , Apteronotus leptorhynchus. Animal Behavior 70: 1355-1365. 76) Oestreich, J and Zakon, HH (2005) Species-specific differences in sensorimotor adaptation are correlated with differences in social structure. J. Comp. Physiol A 191(9): 845-856. 77) Oestreich, J, Dembrow, N, George, A. and Zakon, HH (2006) A "sample-and hold" pulse- counting integrator as a mechanism for graded memory underlying sensorimotor adaptation. Neuron 49: 577-588. 78) Zakon, HH, Lu, Y, Zwickl, DJ, Hillis DM (2006) Sodium channel genes and the evolution of diversity in communication signals of electric fishes: convergent molecular evolution. Proceedings of the National Academy of Sciences USA 103: 3675-3680. 79) Novak, AE, Jost, MC, Lu, Y, Taylor, AD, Zakon, HH, Ribera, AB (2006) Gene duplications and evolution of vertebrate voltage-gated sodium channels. J. Molecular Evolution 63: 208 – 221. 80) Stoddard, PK , Zakon ,HH, Markham, MR, McAnelly, ML (2006) Regulation and modulation of electric waveforms in gymnotiform electric fish. J. Comp. Physiol. A 153: 477-487 81) Few, WP, and Zakon, HH (2007) Sex differences in and hormonal regulation of Kv1 potassium channel gene expression in the electric organ: molecular control of a social signal. Developmental Neurobiology 67: 535-549. 82) Liu, H., Wu. M-M., Zakon (2007) Individual variation and hormonal modulation of a

Developmental Neurobiology 67(10): 1289-1304. 83) McAnelly ML, Zakon HH (2007) Androgen modulates the kinetics of the delayed rectifying K+ current in the electric organ of a weakly electric fish. Developmental Neurobiology 67(12): 1589-1597. 84) Jost, MC, Zakon, HH, Hillis, DM, Lu, Y, Kyle, JW, Fozzard, HA (2008) Toxin-resistant sodium channels: Parallel adaptive evolution across a complete gene family. Molec. Biol. & Evol. 25: 1016-1024. 85) Triefenbach, F, Zakon, HH (2008) Changes in signaling during agonistic interactions between male weakly electric knifefish, Apteronotus leptorhynchus. Animal Behavior 75: 1263-1272. 86) Zakon, HH, Zwickl, DJ, Lu, Y, Hillis, DM (2008) Molecular evolution of communication signals in electric fish. J. Exp. Biol. 211: 1814-1818. 87) Liu H, Wu, M, Zakon HH (2008) A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signal. J. Neurosci. 28: 9173-9182. 88) Markham M, McAnelly L, Stoddard P, Zakon HH (2009) Circadian and social cues regulate ion channel trafficking. PLoS Biology 7(9): e1000203. 89) Dembrow, NC, Pettit, DL, Zakon, HH (2010) Calcium dynamics encode the magnitude of a graded memory underlying sensorimotor adaptation. J. Neurophysiology. 103: 2372-2381.

BOOK REVIEWS AND COMMENTARY 1) Zakon, HH (1984) Fish Neurobiology (Ed.) R.G. Northcutt and R. Davis for Copeia. no2. 559-560. 2) Zakon, HH (1991) Electrocommunication in Teleost Fish: behavior and experiments by Bernd Kramer in Trends in Neurosciences. Zakon, H.H. 10

3) Zakon, HH (1992) Neural Nets in Electric Fish by Walter Heiligenberg in Trends in Neurosciences. 4) Zakon, HH (2000) Sensory Exotica by Howard Hughes in Nature Neuroscience. 5) Zakon HH Heeding the Hormonal Call. (2004) Science 305: 349-350. 6) Zakon HH (2006) Divide and conquer: cell addition and aggressive signaling in electric fish. Hormones & Behavior 50: 8-9.

Other Papers from my laboratory 1) Fleishman, L. (1992) Communication in the weakly electric fish Sternopygus macrurus. I. The neural basis of conspecific EOD detection. J. Comp. Physiol. A, 170: 335-348. 2) Dunlap, K.D. (2002) Hormonal and body size correlates of electrocommunication behavior during dyadic interactions in a weakly electric fish, Apteronotus leptorhynchus, Hormones and Behavior 41: 187-194.