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Glossary of Drug Names Y> \C British Approved Name U.s. Adopted Name British Trade Name U.S. Trade Name 00 epinephrine Adrenalin amiloride Midamor Colectril aminophylline Theodrox, Aminodur Lixaminol amiphenazole Daptazole amoxycillin amoxicillin Amoxil Amoxil, Larocin ampicillin ampicillin Penbritin Penbritin, etc. bendrofluazide Aprinox, Neonaclex, etc. Benuron, Naturetin bumetanide Burinex carbimazole carbimazole Neomercazole Methimazole chlormethiazole clomethiazole edisylate Heminevrin chlorthalidone chlorthalidone Hygroton Hygroton chlorothiazide Saluric Diuril theophyllinate oxtriphylline Choledyl Choledyl clofibrate clofibrate Atromid-S Atromid-S clonidine clonidine Catapres Catapres, Combipres clopamide Brinaldix cloxacillin cloxacillin Orbenin Tegopen cyclopenthiazide Navidrex debrisoquine debrisoquine Declinax deslanoside Cedilanid-D C) Q diazepam Valium Valium CIl diazoxide diazoxide Eudemine Hyperstat CIl digitoxin digitoxin Digitaline Crystodigin, Digitaline ~ Nativelle Nativelle, Purodigin 0 digoxin digoxin Lanoxin Lanoxin 0'"' edrophonium edrophonium Tensilon Tensilon 2 ethacrynic acid ethacrynic acid Edecrin CIQ Edecrin Z frusemide: Lasix Lasix ~ gitalin GitaJigin a /D CIl C) glyceryl trinitrate ni troglycerin Trinitrin Nitrol 0 guanethidine guanethidine Ismelin Ismelin - '" hydrallazine hydralazine Apresoline Apresoline '"III .:! hydrochlorothiazide Esidrex Hydrodiuril, Oretin 0 hydroflumethiazide Naclex Diucardin, Saluron ..... isoproterenol Saventrine Isuprel t:I lanatoside-C lanatoside-C Cedilanid Cedilanid (Jqa levodopa L-dopa Larodopa, Brocadopa, Levodopa, Bendopa, Z Sinemet, Madopar Dopar, Larodopa III 51 lignocaine lidocaine Xylocaine Xylocaine III mefruside mefruside Baycaron '" metaraminol metaraminol Aramine Aramine methyldopa methyldopa Aldomet Aldomet minoxidil minoxidil nikethamide nikethamide Coramine Coramine ouabain ouabain Ouabaine Ouabain oxprenolol oxprenolol Trasicor phenylbutazone phenylbutazone Butazolidin Butazolidin phenylephrine phenylephrine Neosynephrine Neosynephrine phenytoin phenytoin Epanutin Dilantin pindolol Visken practolol practolol Eraldin procainamide procainamide Pronestyl Pronestyl propanolol propanolol Inderal Inderal Thean quinidine quinidine Quinidine Sulfate reserpine reserpine Serpasil Serpasil, etc. salbutamol Ventolin Ventolin spironolactone Aldactone Aldactone thioridazine thioridazine Melleril Mellaril triamterene Dytac Dyrenium \.» warfarin warfarin Marevan Coumadin, etc. \D \D Index

A wave, 228 Aneurysm Accessory bundles, 78 aortic, 160, 243, 378 Acetyldigoxin, 267 coronary, 193 Acetylstrophanthidin, 267, 272 dissecting, 51, 157, 241, 378 Acidosis, 216, 223 ventricular, 15, 302, 388-390 l3-Adrenergic blockade, 105, 186-188, Aneurysmectomy, 344, 390 246, 306, 322, 351 Angina pectoris, 127 Age changes anemia, 195, 263 baroreceptor function, 104-106 aortic valve disease, 195, 237, 377- blood pressure, 102-104, 145-147 378 cardiac output, 81-98 hypothyroidism, 262 cerebral blood flow, 107-109 ischemic heart disease, 3, 194-195, conduction system, 57-61,64-67 263, 299, 323, 338, 383-384, drug handling, 185, 257, 275, 318-319 386,388 myocardium, 12-13, 58-59 rheumatic heart disease, 232 valves, 13 syphilitic aortitis, 195 Albuminuria, 165 Angiocardiography, 141, 236 Alcoholism, 24, 121 Angiography, 370, 390 Aldosterone, 181, 280, 283 Angiotensin, 104 Aldosterone antagonist, 224 Ankylosing spondylitis, 49, 76, 241 Alkaline phosphatase, 19 Annuloplasty, 374, 382 Alkalosis, 283, 293 Antacids, 272 Alveolocapillary block, 226 Antibiotics, 44-45, 184, 202, 221, Amiloride, 186, 280, 283, 285 252,256-257,294,355 Aminophylline, 233-234, 285 drugs, 272 Amiphenazole, 224 Anticoagulants, 234, 293-294, 305, Amoxycillin, 222 339,374,381,386 Ampicillin, 222 Antihypertensive therapy, 144, 158, Amyloid, amyloidosis, 11, 17,52,59, 173-174, 184-185, 190 68-69,121 Antinuclear antibody, 322 Anacrotic pulse, 237 Anxiety state, 328 Analgesics, 305 Aorta Anemia aneurysm, 160, 243, 378 angina, 195, 263 coarctation, 13, 391 bacterial endocarditis, 258 dilatation, 51, 243-244 cardiac failure, 263, 288 ~ssection,51, 157,241,378 cardiac pathology, 13, 24 rupture, 241 methyldopa, 187 unfolding, 137 401 402 Index

Aortic incompetence , 186, 199, 312,323 ankylosing spondylitis, 76 Asymmetrical septal hypertrophy, 21 bacterial endocarditis, 254 Asystole, 307, 328, 347, 350 clinical features, 241-244 Atheroma, Atherosclerosis, 15, 22, murmur, 134, 238, 254 159, 183 pathology, 49-51 Atrial dilatation, 36, 233, 244, 388 pulse, 128 Atrial fibrillation rheumatic, 232 bacterial endocarditis, 254 surgery, 378-381, 385 cardiac infarction, 195, 203, 300- syphilitic, 242-243, 294 312 Aortic stenosis diagnosis, 131, 327-328, 330 clinical features, 134, 237-241, 348 epidemiology, 8 epidemiology, 6 mitral valve disease, 232-234, 236 murmur, 134 paroxysmal,335 pathology, 13, 28-32,73,77 pathology, 68-69, 316 pulse, 128, 349 pericardial disease, 264 rheumatic, 232, 376 physiology, 318 surgery, 376-382 prognosis, 294 Aortic valve thyrotoxicosis, 260-261 bicuspid, 13, 376, 391 treatment, 270-271, 275, 319, 322- calcification, 11, 239, 245, 250 323,335,353,374 cusp prolapse, 241 Atrial flutter rupture, 46,241 cardiac infarction, 203, 300, 302, quadricuspid, 13 306 replacement, 378-382 pathology, 316 ring, 49-51, 73, 350 pulmonary embolism, 335 sclerosis, 26, 49, 134, 239, 250, treatment, 319, 323, 327, 330, 335 348, 378 Atrial hypertrophy, 129 vegetations, 259 Atrial myocardium, 17, 58, 68, 75 Aortitis, 50, 138, 195, 241 Atrial myxoma, 24, 236 Aortopathy,50 Atrial pacing, 374 Apexcardiography, 139-140 Atrial septal defect, 13, 130, 133, Arrhythmia, 12, 134, 180, 228, 315- 245, 390 346 Atrial systole, 129, 357 atrial, 58, 68, 75, 316, 380 Atrial tachycardia, 271, 322, 327-328, cardiac infarction, 195, 300, 302, 331 304-305 Atrial thrombosis, 138, 234 nodal, 203, 339 Atrioventricular block (see Heart block) sino-atrial, 17 Atrioventricular node sinus, 324 anatomy, 60-61 supraventricular, 306, 321, 326,329 arrhythmia (See Junctional, etc.) Arterial elasticity, 147 physiology, 317 Arterial embolism, 48, 232, 244,.388 Atrophy, brown, 12 Arterial peo2 (See also Hypercapnia), Atropine, 113, 275, 305-307, 328, 98,218-219,221 333, 345 Arterial P02 , 98, 305 Autonomic nervous system, 118, 316 Arterial pulse, 128, 316 Arterial resistance, 270 Bacteremia, 44, 255 Arteriography, 309, 383 Bacterial endocarditis, 44-47, 250-279 Arteritis, 193 aortic valve disease, 46, 241,250 Ascites, 219, 261, 264 clinical features, 236, 252-257 Index 403

Bacterial endocarditis (cont'd) Bradycardia (cont'd) enterococcal, 45, 251 pacemaker failure, 358 mucoid degeneration of mitral reflex, 104-106 valve, 40-41, 250 Bradytachy syndrome, 328, 353 pathology, 44-47 Brain (See Cerebral) pneumococcal, 46 Bronchitis, 6, 186, 216, 221, 225,232, prognosis, 258-259 287,310 rheumatic heart disease, 45, 233, , 222-223 250 Brucella,31 staphylococcal, 45-46,251-252,259 Bundle branch streptococcal, 45,251-252, 259 anatomy, 33, 61-68 treatment, 257-259 pathology, 69-77 Bacteriuria, 181 Bundle branch block Ballistocardiography, 141 left, 8, 77, 140,180,195,238,302, , 121, 228 344,352 Baroreceptors, 103-120, 241, 270 right, 8, 77,132,135,195,344, Basal metabolic rate, 85, 95 352 Bed rest, 289, 294 Bundle of His Belladonna, 328 accessory, 78 Bendrofluazide, 186 anatomy, 33, 61-68 Blood culture, 45, 236, 255 electrography, 135,353 Blood flow, pathology, 69-78 cerebral, 95, 104, 107, 127,156, 317 Calcification skeletal muscle, 95 aortic annulus, 11 skin, 95 aortic knuckle, 137 splanchnic, 95 aortic valve, 11, 25-26, 29, 134,2.39, Blood gases (See also Arterial PC02 , 245,250,379 P02 , Hypercapnia, Hypoxia), ascending aorta, 138, 243 215,221,371,380 cardiac aneurysm, 15, 138 Blood pressure (See also Hyperten- metastatic, 35 sion, Hypotension) mitral annulus, 11, 32, 47, 73, 235, cardiac infarction, 300 250,350 casual, 154-156 mitral valve, 25,42 diastolic, 152, 180 pericardium, 138, 264 digitalis, 284 , 269, 273, 309, 316-317 exercise, 87 Cannon wave, 129 hyponatremia, 293 Capillaries, pulmonary, 88, 92-93, normal, 102-103, 128, 144-145, 214,372,377 177-179 Capillary pulsation, 241 regulation, 101-123 Carbimazole, 261 systolic, 152-177 Carbon dioxide (See Arterial PC02 , Blood transfusion, 263 Hypercapnia) Blood volume, 93, 97, 115 Carcinoid heart disease, 51, 245 Bradyarrhythmia, 237, 272, 345 Carcinoma, 24,47-48,76,121,251, Bradycardia 253,259,263 (j-adrenergic blockade, 186, 351 Cardiac arrest, 321, 346 cardiac infarction, 201, 204, 304, Cardiac aneurysm, 15, 51, 138, 157, 307 241,378 complete heart block, 347-349 Cardiac catheterisation, 81, 91, 97, digitalis, 274-275 141,239,387 404 Index

Cardiac failure (see Congestive heart Catecholamines, 113, 118, 120, 181, failure, Left ventricular failure) 322,351 Cardiac impulse, 129, 219 Cerebral Cardiac index, 81, 377 anoxia, 200 Cardiac infarction (See also Ischemic blood flow, 95,104,107,127,156, heart disease) 288,317,327 arrhythmias, 195, 300, 302, 304- embolism, 52 305,327,340 infarction, 103, 145, 158, 160,164- complications, 15-16, 297-312 165,180,184,201-202,333, congestive heart failure, 288, 292 381 coronary care, 297-312 ischemia, 348 epidemiology, 5, 8, 160 metabolism, 107 heart block, 75-77,350, 357 vascular disease, 103-108, 112, 116, hypertension, 160 122,317 left ventricular failure, 194 Chlordiazepoxide, 305 pathology, 15,49, 196 Chloride, 279, 283 surgical treatment, 357, 369, 383- Chlorothiazide, 280 388,392 Chlorpromazine, 121 symptoms, 127, 197-206, 299 Chlorthalidone,280 Cardiac massage, 345 Cholesterol, 164 Cardiac metastases, 24 Cholestyramine, 272, 275 Cardiac monitoring, 136, 295, 327, , 222 347 Chordae tendineae, 33-34, 37, 39,42, Cardiac neurosis, 292, 311 371 Cardiac output rupture, 40, 46, 372, 374 /3-adrenergic blockade, 186 Chorea, 232 cardiac infarction, 127, 196, 202, Cigarettes, 164, 310 307 Cineangiography, 388 cardiac surgery, 374, 380 Clockwise rotation, 220 complete heart block, 307 Clofibrate, 268 congestive heart failure, 290 Clubbing, 226, 254 digitalis, 270, 272 Coarctation of aorta, 13, 391 normal, 81-98 Collagen, 12 syncope, 110, 122 Collagen disease, 50 Cardiac rehabilitation, 311 Collapsing pulse, 241 Cardiac rupture, 15-16 Commissurotomy, 369, 373 Cardiac skeleton, 12, 60, 65 Confusion, 185, 196, 200,204,219, Cardiac tamponade, 264, 355, 380 237,253,257,261,274,288, Cardiogenic shock, 204-205, 308,323, 299,305,307,312,328,371, 388,390 380 Cardiomyopathy Congestive heart failure clinical features, 245 aortic valve disease, 237,243-244, heart block, 72-73, 75 377-378 pathology, 20-21 arrhythmias, 328, 330, 338 Cardiopulmonary bypass, 369-388 bacterial endocarditis, 254, 258 Cardiothoracic ratio, 137, 180 cardiac infarction, 194, 206, 301, Cardioversion, 204, 271, 274, 306- 308,311,387-389 307, 321,328, 333-339, 344- digitalis, 270-275 345 , 281, 284 Carotid sinus, 103,105,111,211, epidemiology, 3,8,145 270,327,333 heart block, 349, 354, 365 Index 405

Congestive heart failure (cont'd) Diabetes mellitus, 24, 35, 115, 121, hypertension, 157, 160, 164-165, 186,284,299,311 180,184 Diamorphine, 305 hypothyroidism, 261-262 Diarrhea, 115 mitral valve disease, 232-234, 372 Diazepam, 289, 335, 339, 344 pathology, 14, 24 Dicrotic notch, 147 prognosis, 294 Diffusing capacity, 226 pulmonary heart disease, 211-212, Digitalis, 267-276, 318-321, 327-339 217,220,229 absorption, 272 signs, 129 actions, 269-270, 275, 316, 318- 321 symptoms, 127 arrhythmias, 196, 306, 327-339 thyrotoxicosis, 260-261 assay, 288, 321 treatment, 270, 272-275, 281, 284, biovailability, 267 287-295.323 cardiac infarction, 204,306 Congo red test, 18 cardiac surgery, 374, 380 Conn's syndrome, 184 intoxication, 136,204,273,290, Constrictive pericarditis, 264 321,340,351 Cor pulmonale (See Pulmonary heart normal heart, 92 disease) potassium, 269, 272, 283 Coronary protein binding, 268 aneurysm, 193 pulmonary heart disease, 225 arteriography, 309, 383-384, 388 sensitivity, 17, 283, 319 artery serum levels, 273, 394, 321 bypass, 387,392 thyrotoxicosis, 260-261 disease (See Ischemic heart disease, Digitoxin, 267, 272 Cardiac infarction) Digoxin (See Digitalis) surgery, 369-383 Diodrast clearance, 94 blood flow, 95, 270 Diphenylhydantoin, 274-275, 321, care, 297-312 324,334,345 sinus rhythm, 339 Diphtheria, 68,72 Corticosteroids, 226, 340 Dissecting aneurysm of aorta, 51, 157, Cough, 205 241,378 syncope, 110 Disseminated lupus erythematosus, Counterclockwise rotation, 135 76, 188, 322 Countershock (See Cardioversion) Diuretics, 185-187,219,224,261, Coxsackie viruses, 23, 44, 264 272-273,276,279-280,283- Cushing's syndrome, 181, 183 285,306,311-312,328,365 Cusp fenestration, 379 Dopamine, 380 Cyanosis, 96, 199, 203, 218, 226,228 Drug rash, 187,280,283 Cystic medionecrosis, 51, 378 Dyazide, 186 Dye dilution, 81-82, 94 Dyspnea, 127, 194,218, 244,285, Defibrillation (See also Cardioversion), 287-288,302,377 308 Dehydration, 115, 121 ECHO viruses, 44 Dementia, 108, 183-184 Echocardiography, 142, 233, 236, Dental extraction, 258 239,264 sepsis, 251 Ectopic beats, 8,131,135,274,302 Depression, 187, 253, 283, 311-312,327 atrial, 323 Deslamoside, 92, 333 ventricular, 195-196, 203, 236,307, Diabetes insipidus, 115 319,321,340,351 406 Index

Eczema, 187 Endotracheal intubation, 224 Edema, 187-188, 194, 215, 219, 271, Enterococcus, 45,251 281,288,290,293-294 Ephedrine, 122,238 Edrophonium, 333 Epilepsy, 110, 112, 348 EDTA,273 Epinephrine, 345 Effusion Erythrocyte sedimentation rate, 236, pericardial, 261, 264 256,258,293 pleural, 138, 194, 261, 293 Erythropoietin, 216 Ejection, cardiac, 91, 132 Esophageal electrocardiographic leads, Elastic stockings, 122 344 Electrocardiogram (See also Arrhyth- Essential hypertension (See Hyperten• mia, Bradycardia, Bundle of sion) His, Ectopic beats, Heart block, Ethacrynic acid, 186, 280-281, 284- Tachycardia) 285, 308 clockwise rotation, 220 Exercise, 83-84, 96-98 counterclockwise rotation, 135 Extrasystole (See Ectopic beat) epidemiology, 5-8 esophageal leads, 344 Failure (See Congestive heart failure, H-V time, 135, 353 Left ventricular failure) intracardiac, 135, 326-327, 353 Fainting (See Syncope) left atrial hypertrophy, 233 Fallot's tetralogy, 13 left ventricular hypertrophy, 6-7, Fenamates, 268 135,157,165-173,244 Fever, 206, 253-257, 293, 328 Minnesota code, 6 Fibrinoid necrosis, 183 monitoring, 136,295,327,347 Fibrinolysis, 227 P mitrale, 233 Fibrosing alveolitis, 226 P-R interval, 135, 270, 272, 274, Filiform excrescences, 52 317,322,324-325,335 Fludrocortisone, 122 P wave, 220, 244, 264, 317, 324- Folic acid, 203 325,331,339,341 Framingham study, 143-175 Q/QS patterns, 6, 135 Frusemide (Furosemide), 186,224, Q-T interval, 270 263,280-283,305, 308, 312 right atrial hypertrophy, 244 Fungal endocarditis, 45-46, 252 right ventricular hypertrophy, 8, 219- 220,233,245 Gallop rhythm, 206, 287-288 S-T-T changes, 6, 91, 135, 165 Glomerular filtration, 204, 215, 275, Twave, 8, 135, 220, 261, 264, 317 279,284-285 Electrocardioversion (See Cardioversion) Glucose, 160, 164 Electrolytes (See also , Goiter, 260 Potassium, Sodium), 293, 357 Gout, 186, 284 Embolectomy, 234 Gumma, 34 Embolism, 15,52,253-254, 258,315, 338,381 Heart block (See also Bundle of His) cerebral, 52 bifascicular, 302, 352 coronary, 52, 193 calcific, 69 pulmonary, 227 complete systemic, 48, 232, 234 clinical features, 129,204, 300, Emphysema, 216-218, 220, 228 304,347-349 Endocarditis (See Bacterial endocar• digitalis, 272, 274 ditis, Fungal endocarditis, non• epidemiology, 8,365-366 bacterial thrombotic endocar• pathology, 17, 23, 33, 47, 64, 69- ditis, Rickettsial endocarditis) 76 Index 407

Heart block (cont'd) Hypertension (cont'd) complete (cont'd) epidemiology, 143-175 prognosis, 349, 365-366 cardiac infarction, 299, 305, 310 treatment (See also Pacemaker), malignant, 181-183 307,324,338,345,347-366 management, 184-190, 280, 285, first degree, 8, 244, 272,323 310 intraventricular, 321 pathology, 13, 35, 51,66,77,182- partial, 321-323 183 second degree, 8,204,272,274,353 Hypertensive heart disease, 2, 5, 210, trifascicular, 353 294 Heart failure (See Congestive heart Hypertensive retinopathy, 158 failure, Left ventricular failure) Hyperthyroidism (See Thyrotoxicosis) Heart sounds, 219 Hyperuricemia, 186, 284 first, 130, 138, 233 Hypocapnia, 109 fourth, 132,138,219 Hypoglycemia, 195 second, 131, 134,219, 228,237, Hypokalemia (See also Potassium), 186, 239,241,243 269,272-274,285,331,340 th~d, 132,138,196,219,233,235, Hypomagnesemia (See also Magne• 302 sium),274 Heart volume, 97 Hyponatremia, 117, 273, 276, 293 Hematuria, 184, 257 Hypotension Hemiblock (See also Heart block, bi- aortic valve disease, 237 fascicular) cardiac :nfarction, 205 epidemiology, 8 drugs, 115,121-123,321,322 cardiac function, 91 postural (orthostatic), 104, 109, ischemic heart disease, 195 114-123 pathology, 77 sodium depletion, 293 significance, 135 Hypotensive drugs (See Antihyper• Hemiplegia, 201 tensive drugs) Hemochromatosis, 24 Hypothermia, 373 Hemoglobin, 97 Hypoxemia (See also Arterial P02 ), Hemophilus influenzae, 222 214, 216, 226, 269, 271, 274, Hemoptysis, 203, 293 288, 357 Heparin, 305 Hepatic Immunoglobulins, 19 congestion, 274 Incontinence, 285, 348 failure, 305 Infarctectomy, 390 function, 324 Infective endocarditis (See Bacterial, Hepatitis, 187 Fungal, Rickettsial endocar• Hepatojugular reflux, 129,219, 288 ditis) Hepatomegaly, 244, 288 Innominate vein, 128 His bundle (See Bundle of His) Intermittent claudication, 145, 160, H-V time, 135, 353 165 Hydrochlorothiazide, 285 Internodal atrial myocardium, 58-59, Hypercapnia (See also Arterial PC02 ), 67-68,75,316 199,214,216,218 Interventricular septum, 23, 64-65 Hyperglycemia, 188,284 Intracardiac electrocardiogram, 326- Hyperkalemia (See also Potassium), 327 273,276,346 Intrathoracic pressure, 105, 214 Hyperlipidemia, 160,261,310 Ischemic heart disease (See also Hypertension (See also Blood Pressure) Coronary, Cardiac in faction) clinical features, 133, 183-184 epidemiology, 2, 3, 5, 145, 160,180 408 Index

Ischemic heart disease (cont'd) Left ventricular hypertrophy (cont'd) clinical aspects, 193-206, 210,215, ischemic heart disease, 1;:S, 1 ~o 260-261,294,297-312,329,340 mitral incompetence, 233, 372 pathology, 12, 15, 22, 72, 75-77, Left ventricular systolic pressure, 377 85, 193 Lenegre's disease, 70 surgery, 383-390 Leucocytosis, 293 Isoprenaline (Isoproterenol), 307,321, Lev's disease, 70 328,345,347,350-351,358, Lidocaine (lignocaine), 274, 307, 321, 374,385 340,344-345,351,358 Isotope cardiography, 141 Lipofuscin, 12 Isotope dilution, 268 Magnesium, 269, 273-274, 276, 317 Jet lesions, 36-37, 41, 345-346 Malar flush, 233 Jugular venous pressure, 219, 264 Malignant hypertension, 181-183 Jugular venous pulse, 228 Marfan syndrome, 42 Junctional rhythm, 325, 329 Maximal heart rate, 86 Junctional tachycardia, 330 Maximal oxygen uptake, 96 Medial sclerosis, 128 Kerley's lines, 138, 233, 288 Meprobamate, 121 Kyphoscoliosis, 129, 137, 210, 228, Mercurial diuretics, 280, 283 264 Mesothelioma, 75 Metaraminol, 385 Lambl's excrescences, 43 Methyldopa, 187 Lean body mass, 85 Minnesota code, 6 Left anterior hemiblock (See Hemi• Minoxidil, 188 block) Mitral annulus, 32,47,73,138,350, Left axis deviation, 77, 91, 135, 352 372 Left ventricular aneurysm, 15, 302, Mitral cusps, 21, 36-44, 47,250,373 388-390 Mitral incompetence Left ventricular dilatation, 22,129 bacterial endocarditis, 35, 44, 47, Left ventricular failure 250,254 aortic valve disease, 377, 383 nonrheumatic, 34-42, 196, 235-236, clinical features, 199, 287-288 245,250,372-374,389 epidemiology, 3 pathology, 34-44 hypertension, 185 rheumatic, 42-44, 232-234, 372-374 ischemic heart disease, 194, 199, Mitral stenosis, 134, 202, 232-233, 205,310,388 371,382 mitral incompetence, 372 Mitral valve radiology, 138, 288 mucoid degeneration, 35, 47,236 treatment, 281, 290 prolapse, 47, 141, 236 Left ventricular hypertrophy replacement, 373-374, 389 aortic valve disease, 13, 134, 237- vegetations, 45 244,377-378 Mitral valvotomy, 373-374 cardiomyopathy, 13, 20 Monoamine oxidase inhibitors, 121- causes, 13 122 clinical features, 129, 140 Morphine, 228, 289, 305,307,331 conduction defects, 65-66, 73, 349 Multiple system disease, 118 electrocardiographic, 8,135,157, Multivalvular disease, 245, 382-383 165 Murmur epidemiology, 8 aortic diastolic, 238, 243 hypertension, 6, 13, 65, 157, 165,180 Austin Flint, 134 Index 409

Murmur (cont'd) Pacemaker, pacing (cont'd) early diastolic, 253-254 demand,357-359 ejection, 133, 237, 241, 243, 245, electrode displacement, 354-355 250,254 endocardial, 354, 357 late systolic, 35, 133, 250 failure, 358-359 mid-diastolic, 233 fixed-rate, 357 -359 pansystolic, 133, 233, 235, 244, 250 induction, 363 regurgitant, 129, 133 isotopic, 363 systolic, 34, 133, 235, 239 lithium-iodide, 365 Mycoplasma, 44 longevity, 360 Myocardial telephone transmission, 358 abscess, 46 threshold rise, 358 fibrosis, 15, 91 transvenous, 307, 356 granuloma, 23 Packed cell volume, 216, 263 infarction (See Cardiac infarction) Paget's disease, 35, 73 Myocarditis, 15,23,72,263 Palpitation, 204 Myoclonus, 218 Papillary muscle, 64 Myofibers, 15,21,24 dysfunction, 196, 235, 245 rupture, 16, 235, 372, 388-389 Neomycin, 272 Paranoia, 371, 380 Nephrosclerosis, 158 Parkinsonism, 119-120, 187 Neuropathy, 120-121 Patent ductus arteriosus, 13, 392 Neurosyphilis, 241, 244 Peak expiratory flow rate, 288 Nikethamide, 224 Penicillin, 257 Pentazocine, 305 Obesity, 311 Pericardial Obstructive airway disease, 210, 318 calcification, 138, 264 Oliguria, 206 effusion, 261, 264 Olivopontocerebellar atrophy, 119 rub, 206,261, 264,355 Opening snap, 233,236 Pericarditis Osler's nodes, 254 constrictive, 9, 264 Osteitis deformans (See Paget's purulent, 264 disease) viral,262 Ouabain, 267, 272 Peripheral vascular disease, 180 Oxalosis, 24 resistance, 104 Oxprenolol, 186, 219, 222-223,226, Petechiae, 258-259 228-229 Phenobarbitone, 331 Oxygen, 305 Phenylbutazone, 268 Oxygen uptake, 96 Phenylephrine, 104, 122, 345 Phenytoin (See Diphenylhydantoin) P cells, 57, 66, 68 Pheochromocytoma, 181, 184, 322 pH, 269, 271, 316 Phonocardiography, 138, 233, 239 P mitrale, 233 Physical fitness, 310 P-R interval, 135, 270, 272, 274, training, 93-94 317,322,324,325,335 work capacity, 97 P wave, 220, 244, 264, 317, 324-325, Pindolol, 186 331,339,341 Plasma proteins (See also Hypopro- Pacemaker, pacing, 321, 328, 333, teinemia), 19, 236 346 Plasma volume, 216 atrial, 333 Pneumococcus, 46, 222 battery depletion, 359 Poliomyelitis, 44 410 Index

Polyarteritis, 76, 193 Pulmonary heart disease, 6, 209-210, Polycythemia, 216, 222 215,225,228,290,294 Polyneuropathy, 121 Pulmonary hypertension, 227, 245 Potassium (See also Hyperkalemia, Pulmonary incompetence, 134, 219, Hypokalemia) 245 depletion, 7, 134, 274, 276, 283, Pulmonary infarction (See also Pul• 293 monary embolism), 203, 227 dietary, 283 Pulmonary valve disease, 13, 245, 391 intravenous, 331, 345 Pulmonary vascular resistance, 214, loss, 224, 281 225 megaloblastic anemia, 263 Pulmonary venous hypertension, 138 myocardial, 76, 269, 273, 316 Pulmonary venous pressure, 199, 371 serum level, 306, 308 Pulmonary volumes, 97 supplements, 186, 263, 272, 280, Pulse 283, 290, 292-293, 311, 331 anacrotic, 237, 349 Practolol, 186, 305, 323, 327 bisferiens, 238 Precordial thump, 307 collapsing, 241 Preejection period, 140 paradoxus, 264 Preexcitation syndrome, 78 peripheral, 128, 179 Procainamide, 307, 322, 334-335, Pulse pressure, 87, 237, 241, 243, 339-340, 344-345 377 Prognosis Pulse wave recording, 147 aortic valve disease, 243-244, 294, Pyelonephritis, 181 377-378 Pyuria, 181, 184 bacterial endocarditis, 258-259 complete heart block, 349 Q/QS pattern, 6, 135 congestive heart failure, 294-295 Q-T interval, 270 fibrosing alveolitis, 226 Quinidine, 323, 333-335, 338-340, ischemic heart disease, 294, 301- 344-345 302, 384-385 pulmonary heart disease, 225, 294 Radioimmunoassay, 268, 321 rheumatic heart disease, 234, 372 Radioiodine, 261, 294 Propanolol, 87, 186, 261, 274, 321- Radiology, 137 323, 327 -328 Red cell mass, 216 Proptosis, 218 Red cell viscosity, 216 Prothrombin time, 294 Rehabilitation, 292, 304, 309 Prosthetic valves, 52, 371, 374-375, Reiter's disease, 49 380-383 Renal artery occlusion, 181 Proxyphylline,222 Renal blood flow, 94, 215 Psittacosis, 44 Renal failure, 204, 276, 285, 305, Pulmonary artery pressure, 87 -89,211 328,332,349,354 Pulmonary blood flow, 211 Renal function, 24, 158, 185, 196, Pulmonary capillaries, 88, 92-93,214 271-272,275,280,284-285, Pulmonary compliance, 226 290 Pulmonary edema, 184, 199,301- Rerun, 122, 182, 186 302,305,308,372,378 Reserpine, 187, 327 Pulmonary embolism, 68, 203, 233, Respiratory, 288, 293-295, 335, 338, 356, acidosis, 223 386 infection (See also Bronchitis), 288, Pulmonary fibrosis, 225 293-294 Pulmonary function, 97, 210, 226,228 stimulants, 224 Index 411

Restlessness, 205, 237, 289 S-T-T changes, 6, 91,135,165 Retention of urine, 306-307 Staphylococcus, 45-46, 251, 259 Rheumatic Steroids, 45, 345, 351 carditis, 29, 44 Stokes-Adams syndrome, 321, 345, fever, 35,44, 231-232, 250, 371, 347-348,353,365 382 Streptoccus, 45, 251, 259 heart disease, 2, 6, 29, 31, 39,43- Streptomycin, 257 44,68-69,231,237,241,244, Stroke (See also Cerebral infarction), 250,336,338,372,376 165,184,202 Rheumatoid Stroke volume, 87, 91, 93,140-141 arthritis, 76 Subaortic stenosis, 20 granuloma, 32, 49 Subarachnoid hemorrhage, 158 Rickettsial endocarditis, 32 Sudden death, 14-15,41,200,297, Right atrial hypertrophy, 129, 244 304,357,377 Right ventricular hypertrophy, 8,129, Sulfonamides, 184, 268 218-220,233,245 Superior mediastinal obstruction, 244 Rigidity of vessels, 84, 147 Sweating, 115, 119, 184, 198, 205, 237, 328-329 Salbutamol, 222 Sympathetic nervous system, 103, Salt (See also Sodium) 188 intake, 181 Syncope restriction, 185, 289, 337-338 aortic valve disease, 237,348-349, Sarcoidosis, 23 377 Sarcoma, 75 arrhythmias, 328-329 Scoliosis, 129, 137 cardiac infarction, 195-196, 201 Septicemia, 259, 356 carotid sinus, 111 Serological tests, 243 causes, 110-114 Sick-sinus syndrome (See also Sino• cough, 110 atrial disease), 327-328,330, defecation, 114 339 definition, 104, 109 Sino-atrial heart block, 196, 204, 345, 347- arrhythmia, 17 349,358,365 block, 68, 345 left atrial myxoma, 236 disease, 68, 353 micturition, 113-114 node, 57, 67-68, 316-317 pulmonary embolism, 203-228 Sinus Syphilitic arrest, 68, 328, 353 aortic incompetence, 50, 244, 294 arrhythmia, 324 aortitis, 50, 138, 195 bradycardia, 68, 203, 261, 307,321, gumma, 23 323,327-328,345,353 heart disease, 241 tachycardia, 203, 302, 323, 327- ostial involvement, 193 328 Systolic click, 35, 236 Sleep, 105 Systolic pressure, 87, 152, 177, 300 Sodium Systolic time intervals, 140 bicarbonate, 345 depletion, 293 Twave,8, 135, 220,261, 264, 317 intake, 181 Tabes dorsalis, 120, 231 lactate, 345 Tachyarrhythmia, 195, 201, 274,329 restriction, 337-338 Tachycardia Spinal cord, 119, 120, 122 atrial, 271, 322, 327 -328, 331 Spirononlactone, 186, 268, 280, 285 cardiac infarction, 271 412 Index

Tachycardia (cont'd) , 284 junctional, 330-331 pulmonary embolism, 203, 293 Vagus nerve, 103, 113, 316 sinus, 203,302,307,323,327-328 Valsalva maneuver, 105, 114, 332 supraventricular, 271, 274, 302, Valvotomy, 373 306, 318-319, 323, 330 Valvulitis, 29, 44 ventricular, 333, 340-341, 344-345 Valvuloplasty, 374 Tamponade,264,355,380 Varicose veins, 117 , 185, 187, 272-273, 276, Vasovagal attack, 348 279-280, 283-285, 312 Vegetations, 35, 45, 47, 259 Thioridazine, 289 Vein graft, 385 Thrill, 238 Venesection, 223 Thromboembolism, 201, 228,305, Venous disease, 288, 293 374 Venous pressure, 128-129, 194,244, Thrombophlebitis, 117 264,270-271,288 Thyroid function tests, 260, 262 Venous pulse, 128-129, 133, 244,290 Thyroid nodule, 260 Venous thrombosis, 293, 295, 305,345 Thyrotoxicosis, 13, 24, 218, 260,271, Ventilation, assisted, 224 276,288,292,322-323,328, Ventilation-perfusion relationshps, 336, 338 210 Thyroxine, 195, 262 Ventricular fibrillation, 204, 274,308 Tracheostomy, 224 Ventricular filling pressures, 88, 91 Transient ischemic attacks, 103 Ventricular septal defect, 389 Tranquillizers, 121, 331 rupture, 16 Triamterene, 186, 280, 283 Ventricular septum, 64 Tricuspid Vertebrobasilar disease, 348 incompetence, 51, 129, 219, 244, Vitamin B12 deficiency, 263 372, 382 Vomiting, 204, 228 stenosis, 51, 244 valve disease, 36, 51, 60, 232, 382- Wandering pacemaker, 324 383 Warfarin, 268, 311 Tuberculoma, 34 Wolff-Parkinson-White syndrome, Tuberculosis, 23 78 Tyramine, 122 derivatives, 279 , 284, 290, 293 Uremia, 204 Yellow vision, 274