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AMERICAN PHYSIOLOGICAL SOCIETY

2018 PUBLICATIONS CATALOG

JOURNALS v COLLECTIONS v APSSELECT v INFORMATION v OTHER PUBLICATIONS v ABOUT v SUBMIT SUBSCRIBE JULY 2013 f VOLUME 115 Journal o APPLIEDJournal of AMERICAN JOURNALNUMBER 1 OF august 2016 Y OG ® PHYSIOLOGYno.2PHYSIONeurophysiologyL featured research a | multidisciplinaryread more > neuroscience journal volume 310 ISSUE 1 EDITORIALA Lipopolysaccharide downregulates macrophage-derived IL-22 to attenuate ITORIALS alcohol induced hepatocyte cell death INVITEDINVITED EDITORIALSED

ARTICLESARTICLES Original Research // Reviews // Editorials // Articles in Press

Overload-mediated skeletal muscle hypertrophy is not impaired by loss of myofiber STAT3 Cell Physiology

Sodium storage in human tissues is mediated by glycosaminoglycan expression Renal Physiology

LETTERS TO THE EDITOR The human coronary vasodilatory response to Overload-mediated skeletal acute mental stress is mediated by neuronal nitric muscle hypertrophy is not oxide synthase ISSUE 2 S impaired by loss of myofiber Heart and Circulatory Physiology DITORIALSORIARIAALSLSL INVITEDININVITENVITED EDITORIALSEDITORIAEDITEDITOE STAT3

ES Cell Physiology ARTICLESARTICL A novel role for primary cilia in airway remodeling Lung Cellular and Molecular Physiology Although the signal pathways mediating muscle protein synthesis and degradation are well characterized, the transcriptional processes modulating skeletal muscle mass and adaptive growth are poorly understood. Recently, studies in mouse models of muscle wasting or acutely exercised human muscle have suggested a potential Cerebral oxygenation and regional cerebral role for the transcription factor, signal transducer perfusion responses with resistance breathing and activator of transcription 3 (STAT3), in adaptive growth. Hence, in the present study we sought to during central hypovolemia GIES define the contribution of STAT3 to skeletal muscle HODOLO Regulatory, Integrative and Comparative Physiology TIVE MET adaptive growth. In contrast to previous work, two INNOVATIVEINNOVA METHODOLOGIESMETHODOLOGI different resistance exercise protocols did not change STAT3 phosphorylation in human skeletal muscle. To directly address the role of STAT3 in load-induced HIGHLIGHTED TOPIC: (i.e. adaptive) growth, we studied the anabolic Development of a reliable, automated screening effects of 14 days of synergist ablation (SA) in skeletal muscle-specific STAT3 knockout (mKO) mice and system to identify small molecules and biologics their floxed, wild type (WT) littermates. Plantaris that promote human β cell regeneration muscle weight and fibre area in the non-operated leg (Control; CON) was comparable between genotypes. Endocrinology and Metabolism R THE EDITO As expected, SA significantly increased plantaris LETTERSLETTERS TO THE EDITOR weight, muscle fibre cross sectional area and anabolic Published by the Americansignaling in WT mice, although Physiological interestingly, this Society Volume 117 Numberinduction was not4 impaired April in STAT3 mKO 2017 mice. Collectively, these data demonstrate that STAT3 is Roles of autophagy and metabolism in 2 of 2 not required for overload-mediated hypertrophy in pancreatic cancer cell adaptation to A mouse skeletal muscle. MERIC environmental challenges PUBLISHEDPUBLISHED BY THE AMERICANA PHYSIOLOGICAL SOCIETY · JAPPL.ORG Gastrointestinal and Liver Physiology

PUBLISHED BY THE AMERICAN PHYSIOLOGICAL SOCIETY

Empowering discovery to improve health www.physiology.org The American Physiological Society (APS) is devoted to advancing scientific discovery, understanding life, and improving health. As a multidisciplinary community of scientists, APS’s goal is to solve the major problems affecting life by empowering discovery to improve health. TABLE OF CONTENTS

Journals ��2 Journal Benefits ��3 Free Trial Information ��3 Journals Digital Library ��4

American Journal of Physiology® ��5

Journal of Applied Physiology® ��9

Journal of Neurophysiology® ��10

Physiological Genomics® ��10

Physiological Reviews® ��11

Physiology® ��11

Advances in Physiology Education® ��12

The Physiologist® ��12

Physiological Reports® ��13

Comprehensive Physiology® ��13 Journal Legacy Content ��14 Book Monograph Series ��14 Information ��15 Tier Definitions ��16 NEW online journals JOURNALS platform

OF THE AMERICAN PHYSIOLOGICAL SOCIETY

The American Physiological Society (APS) is a publisher of journals and books in many disciplines within physiology. The Society publishes 15 distinguished scientific journals and is dedicated to the advancement of physiological research, which has formed the basis for many biomedical advances. The journal publishing program covers the entire spectrum of physiology. These highly regarded, peer-reviewed journals examine major physiological systems from the cellular and molecular to the organ and system levels. APS journals meet the needs of researchers, educators, fellows, students, clinicians, and others in the physiological and biological sciences. APS journals are published and distributed solely by APS, with the exception of Physiology, which is published jointly with the International Union of Physiological Sciences; Comprehensive Physiology, which is published on behalf of APS by Wiley- Blackwell; and Physiological Reports, which is published jointly on behalf of APS and The Physiological Society by Wiley-Blackwell. Information for ordering appears on page 15 of this catalog.

APS JOURNAL TITLES American Journal of Physiology (AJP) consolidated www.physiology.org AJP–Cell Physiology ajpcell.org AJP–Endocrinology and Metabolism ajpendo.org AJP–Gastrointestinal and Liver Physiology ajpgi.org AJP–Heart and Circulatory Physiology ajpheart.org AJP–Lung Cellular and Molecular Physiology ajplung.org AJP–Regulatory, Integrative and Comparative Physiology ajpregu.org AJP–Renal Physiology ajprenal.org Journal of Applied Physiology jappl.physiology.org Journal of Neurophysiology jn.org Physiological Genomics physiolgenomics.org Physiological Reviews prv.org Physiological Reports the-aps.org/prt Physiology physiologyonline.org Comprehensive Physiology comprehensivephysiology.com Advances in Physiology Education advan.org

APS NEWSLETTER The Physiologist the-aps.org/physiologist JOURNAL BENEFITS

FOR LIBRARIANS AND END USERS

• In 2018, the APS journals will be hosted on Atypon’s Literatum online platform, which will offer increased functionality and intuitive navigation for an exceptional online research experience. Physiology.org will continue to offer access to a complete collection of multidisciplinary physiology content from 1898 to the present. NEW AND IMPROVED BENEFITS • Simpler and more efficient management of all APS holdings for librarians

• A special information for librarians section of the website with important information and helpful resources, including access to real-time COUNTER compliant usage reports

• Enhanced cross-platform search with filters for enhanced discoverability

• More accessible linking to full-text content, with the option of a PDFPlus view (enlarged images and linked references); MathJax functionality for cleaner-looking equations

• Altmetric Attention Scores for each article that offer librarians and interested users a glimpse at where and how much articles are being discussed across various media sites

• Immediate access to accepted papers via Articles in PresS, the APS “early view” service for all 10 original research journals

• Personalized profile area for saving favorite journals, articles, and searches and managing email alerts CONTINUED BENEFITS • Global distribution for reaching the broadest readership

• Continued indexing in Index Medicus, BIOSIS Previews, Scopus, Web of Science, and MEDLINE (Physiological Reports is not indexed in Web of Science). Journal content is also accessible through PubMed

• Perpetual electronic archiving/preservation in the LOCKSS and CLOCKSS systems for all APS journal content

FREE TRIAL Experience the APS online journals for 2 months. Fill out the request form at the-aps.org/trial JOURNALS BEST VALUE for DIGITAL LIBRARY institutions

The APS Journals Digital Library is a single online package of the 10 peer-reviewed original research and two review journals of the Society. The Journals Digital Library is available at a significant discount off the individual title rates. Listed below are the journals included in the Digital Library.

AJP–Cell Physiology AJP–Endocrinology and Metabolism AJP–Gastrointestinal and Liver Physiology AJP–Heart and Circulatory Physiology AJP–Lung Cellular and Molecular Physiology AJP–Regulatory, Integrative and Comparative Physiology AJP–Renal Physiology Journal of Applied Physiology Journal of Neurophysiology Physiological Genomics Physiological Reviews Physiology

Online Only Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 $7,680 $8,770 $9,610 Custom Custom tier definitions & custom pricing information on page 16 AMERICAN JOURNAL OF AMERICAN JOURNAL OF PHYSIOLOGY AMERICAN JOURNAL OF PHYSIOLOGY PHYSIOLOGY volume 310 no.2 august 2016 AMERICANvolume 310 JOURNAL OFno.2 AMERICANaugust JOURNAL OF 2016 PHYSIOLOGY PHYSIOLOGY volume 310 no.2 august 2016 consolidated volume 310 no.2 august 2016

2 of 2 www.physiology.org PUBLISHED BY THE AMERICAN PHYSIOLOGICAL SOCIETY

1 of 2 PUBLISHED BY THE AMERICAN PHYSIOLOGICAL SOCIETY

The consolidated American Journal of Physiology (AJP) has been in uninterrupted print publication since 1898. This publication is composed of the seven AJP specialty journals. It is printed monthly in two parts and published online as articles are ready. The most economical way for institutions to subscribe to all seven sections of the American Journal of Physiology is to purchase the consolidated version.

The consolidated American Journal of Physiology contains the following seven section journals.

• AJP–Cell Physiology • AJP–Endocrinology and Metabolism • AJP–Gastrointestinal and Liver Physiology • AJP–Heart and Circulatory Physiology • AJP–Lung Cellular and Molecular Physiology • AJP–Regulatory, Integrative and Comparative Physiology • AJP–Renal Physiology 1 of 2 PUBLISHED BY THE AMERICAN PHYSIOLOGICALVOLUME 314/315 SOCIETY Individual specialty sections published online as articles are ready. 1 of 2 Printed monthly. Two volumes per year. PUBLISHED BY THE AMERICAN PHYSIOLOGICALApproximately SOCIETY 1,800 articles and 17,800 pages per year. ISSN: 0002-9513

Online Only Print & Online Print Only Domestic International Domestic International Tier 1 $3,925 $5,490 $6,055 Tiers 1– 5 $7,055 $7,760 Tier 2 4,815 6,365 7,005 Tier 3 5,525 7,170 7,850 Single Copies & Back Issues Tier 4 Custom Custom Custom Subscriber Non-Subscriber Tier 5 Custom Custom Custom $340 each $680 each tier definitions & custom pricing information on page 16 when available AMERICAN JOURNAL OF PHYSIOLOGY

Cell Physiology

ajpcell.org

Editor: Josephine Adams, PhD, University of Bristol The American Journal of Physiology–Cell Physiology is on the cutting-edge of cell physiology research. Cell biologists, physiologists, biochemists, and biophysicists find this journal essential reading for original innovative work about normal and abnormal cell functions. Stringently reviewed, thorough, and thought-provoking papers are published on the structure and function of cell membranes, contractile systems, and cellular organelles, as well as mechanisms of development, cell-to-cell interaction, gene expression, and neural, endocrine, and metabolic control. AJP–Cell Physiology has a 2016 Impact Factor of 3.602 and a cited half-life of 9.7 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 200 articles and 2,100 pages per year. eISSN: 1522-1563 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $740 $885 $1,045 Custom Custom $50 each $100 each tier definitions & custom pricing information on page 16 when available, through December 2011

AMERICAN JOURNAL OF PHYSIOLOGY

Endocrinology and Metabolism

ajpendo.org

Editor: André Marette, PhD, Laval University The results of original investigation pertaining to endocrine and metabolic systems on levels of organization ranging from the molecular, subcellular, and cellular levels to whole animals, including humans, appear in the American Journal of Physiology–Endocrinology and Metabolism. Areas investigated include the secretion, action, and function of hormones of the endocrine brain, anterior pituitary gland, adrenals, pancreas, thyroid, parathyroid, gonads and reproductive tissue, adipose tissue, and the paracrine and autocrine control of endocrine cell performance. AJP–Endocrinology and Metabolism has a 2016 Impact Factor of 4.142 and a cited half-life of 9.3 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 190 articles and 2,100 pages per year. eISSN: 1522-1555 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $525 $630 $745 Custom Custom $45 each $90 each tier definitions & custom pricing information on page 16 when available, through December 2011 AMERICAN JOURNAL OF PHYSIOLOGY Gastrointestinal and Liver Physiology ajpgi.org

Editor: Nigel Bunnett, PhD, Columbia University A broad range of information is presented in the American Journal of Physiology–Gastrointestinal and Liver Physiology, including papers on digestion, secretion, absorption, metabolism, motility, microbiology and colonization, growth and development, and neurobiology relevant to these organs, as well as those dealing with neural, endocrine, and circulatory control mechanisms. AJP–Gastrointestinal and Liver Physiology has a 2016 Impact Factor of 3.468 and a cited half-life of 9.0 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 220 articles and 2,300 pages per year. eISSN: 1522-1547 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $565 $670 $785 Custom Custom $45 each $90 each tier definitions & custom pricing information on page 16 when available, through December 2011

AMERICAN JOURNAL OF PHYSIOLOGY Heart and Circulatory Physiology ajpheart.org

Editor: Irving Zucker, PhD, University of Nebraska Medical Center The work published in the American Journal of Physiology–Heart and Circulatory Physiology purposefully spans a wide range of cardiovascular investigation—from genetic, molecular, and cellular physiology of the heart and vasculature to human and animal cardiovascular physiology under normal and stressed states. Studies published in AJP-Heart and Circulatory Physiology focus on uncovering underlying mechanisms of normal and abnormal cardiovascular physiology. The international editorial team ensures that the papers published undergo rigorous peer review and provide new mechanistic information to guide our continuously developing understanding of cardiovascular physiology. AJP–Heart and Circulatory Physiology has a 2016 Impact Factor of 3.348 and a cited half-life of >10.0 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 330 articles and 3,400 pages per year. eISSN: 1522-1539 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $1,010 $1,215 $1,435 Custom Custom $75 each $150 each tier definitions & custom pricing information on page 16 when available, through December 2011 AMERICAN JOURNAL OF PHYSIOLOGY Lung Cellular and Molecular Physiology ajplung.org

Editor: Sadis Matalon, PhD (term ends Dec. 31, 2017), University of Alabama at Birmingham Rory Morty, PhD (term begins Jan. 1, 2018), University of Giessen and Marburg Lung Center Original theoretical and research papers are published in the American Journal of Physiology–Lung Cellular and Molecular Physiology dealing with molecular, cellular, and morphological aspects of normal and abnormal function and response of cells and components of the respiratory system. AJP–Lung Cellular and Molecular Physiology has a 2016 Impact Factor of 4.281 and a cited half-life of 8.8 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 230 articles and 2,500 pages per year. eISSN: 1522-1504 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $495 $605 $715 Custom Custom $45 each $90 each tier definitions & custom pricing information on page 16 when available, through December 2011

AMERICAN JOURNAL OF PHYSIOLOGY Regulatory, Integrative and Comparative Physiology ajpregu.org

Editor: Willis Samson, PhD, Saint Louis University School of Medicine The American Journal of Physiology–Regulatory, Integrative and Comparative Physiology specializes in innovative articles that illuminate physiological processes at all levels of biological organization. The contents represent broad interests in regulation, integration, and homeostasis. Significant topics addressed include comparative physiology, regulation and integration in autonomic physiology, behavior, cardiovascular physiology, endocrinology, energetics, fluids and electrolytes, functional morphology, ingestion, periodicity, respiration, and temperature. AJP–Regulatory, Integrative and Comparative Physiology has a 2016 Impact Factor of 2.982 and a cited half-life of >10.0 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 280 articles and 2,600 pages per year. eISSN: 1522-1490 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $710 $850 $1,000 Custom Custom $50 each $100 each tier definitions & custom pricing information on page 16 when available, through December 2011 AMERICAN JOURNAL OF PHYSIOLOGY

Renal Physiology

ajprenal.org Editor: P. Darwin Bell, PhD, University of Alabama at Birmingham With a sterling reputation as one of the finest journals publishing information on kidney and urinary tract physiology, epithelial cell biology, and control of body fluid volume and composition, the American Journal of Physiology–Renal Physiology appeals to scientists from many disciplines. Investigations involve human or animal models, including invertebrates, plus isolated, reconstituted, or artificial organella, or membrane systems or cells. AJP–Renal Physiology has a 2016 Impact Factor of 3.611 and a cited half-life of 8.7 years. VOLUME 314/315 Published online as articles are ready and archived as monthly issues. Printed monthly in the consolidated version of AJP. Two volumes per year. Approximately 300 articles and 2,800 pages per year. eISSN: 1522-1466 (Online)

JULY 2013 VOLUME 115 NUMBER 1 Journal of APPLIED PHYSIOLOGY ISSUE 1 EDITORIALA

INVITEDINVITED EDITORIALSEDITORIALS

ARTICLESARTICLES

LETTERS TO THE EDITOR Journal of Applied Physiology ISSUE 2 INVITEDININVITENVITED EDITORIALSEDITORIAEDITEDITOEDITORIALSORIARIAALSLSLS

ARTICLESARTICLES

INNOVATIVEINNOVATIVE METHODOLOGIESMETHODOLOGIMETHODOLOGIES

HIGHLIGHTED TOPIC:

LETTERSLETTERS TO THE EDITOREDITOR

PUBLISHEDPUBLISHED BY THE AAMERICANMERICA PHYSIOLOGICAL SOCIETY · JAPPL.ORG jappl.physiology.org

Editor: Sue Bodine, PhD, University of Iowa A leader in its field, the Journal of Applied Physiology publishes original papers that deal with normal or abnormal function in six discrete, but often related, areas: 1) respiratory physiology, 2) nonrespiratory functions of the lungs, 3) environmental physiology, 4) temperature regulation, 5) exercise physiology, and 6) interdependence. Priority is given to papers dealing with integrative and adaptive mechanisms. Papers devoted to human research are encouraged. The Journal of Applied Physiology has a 2016 Impact Factor of 3.351 and a cited half-life of >10.0 years. VOLUME 124/125 Published online as articles are ready and archived as monthly issues. Printed monthly. Two volumes per year. Approximately 350 articles and 2,900 pages per year. ISSN: 8750-7587 (Print); eISSN: 1522-1601 (Online)

Online Only Print & Online Print Only Domestic International Domestic International Tier 1 $1,245 $1,745 $1,855 Tiers 1– 5 $2,250 $2,385 Tier 2 1,490 2,040 2,155 Tier 3 1,765 2,280 2,410 Single Copies & Back Issues Tier 4 Custom Custom Custom Subscriber Non-Subscriber Tier 5 Custom Custom Custom $120 each $240 each tier definitions & custom pricing information on page 16 when available Journal of Neurophysiology® a multidisciplinary neuroscience journal Journal of Neurophysiology

Published by the American Physiological Society Volume 117 Number 4 April 2017 jn.org

Editor: Bill Yates, PhD, University of Pittsburgh The Journal of Neurophysiology publishes original articles on the function of the nervous system. All levels of function are included, from the membrane and cell to systems and behavior. Experimental approaches include molecular neurobiology, cell culture and slice preparations, membrane physiology, developmental neurobiology, functional neuroanatomy, neurochemistry, neuropharmacology, systems electrophysiology, imaging and mapping techniques, and behavioral analysis. Experimental preparations may be invertebrate or vertebrate species, including humans. Theoretical studies are acceptable if they are tied closely to the interpretation of experimental data and elucidate principles of broad interest. The Journal of Neurophysiology has a 2016 Impact Factor of 2.396 and a cited half-life of >10.0 years. VOLUME 119/120 Published online as articles are ready and archived as monthly issues. Printed monthly. Two volumes per year. Approximately 530 articles and 6,200 pages per year. ISSN: 0022-3077 (Print); eISSN: 1522-1598 (Online) Online Only Print & Online Print Only Domestic International Domestic International Tier 1 $1,420 $1,985 $2,160 Tiers 1– 5 $2,570 $2,770 Tier 2 1,695 2,305 2,495 Tier 3 2,010 2,605 2,795 Single Copies & Back Issues Tier 4 Custom Custom Custom Subscriber Non-Subscriber Tier 5 Custom Custom Custom $150 each $300 each tier definitions & custom pricing information on page 16 when available

Physiological Genomics

physiolgenomics.org

Editor: Bina Joe, PhD, University of Toledo College of Medicine Physiological Genomics publishes research, reviews, and rapid reports in areas of research focused on uncovering the links between genes and physiology at all levels of biological organization. Topics range from single genes to whole genome, especially concerning links to human physiology, but also any model organism, organ, tissue, or cell. Physiological Genomics has a 2016 Impact Factor of 3.044 and a cited half-life of 8.4 years. VOLUME 50 Published online as articles are ready and archived as monthly issues. One volume per year. Approximately 90 articles and 1,000 pages per year. eISSN: 1531-2267 (Online)

Online Only Single Copies & Back Issues Tier 1 Tier 2 Tier 3 Tier 4 Tier 5 Subscriber Non-Subscriber $345 $420 $495 Custom Custom $65 each $130 each tier definitions & custom pricing information on page 16 when available, through October 2010 Physiological Reviews

prv.org

Editor: Dennis Brown, PhD (term ends Dec. 31, 2017), Harvard Medical School Sadis Matalon, PhD (term begins Jan. 1, 2018), University of Alabama at Birmingham Physiological Reviews provides state-of-the-art coverage of timely issues in the physiological and biomedical sciences. The journal appeals to physiologists, neuroscientists, cell biologists, biophysicists, nutritionists, and clinicians with special interests in pathophysiology. Topics are covered in a broad and comprehensive manner. Ranked number one in its field, Physiological Reviews has a 2016 Impact Factor of 27.312 and a cited half-life of >10.0 years. VOLUME 98 Published online as articles are ready and archived as quarterly issues. Printed quarterly—January, April, July, and October. One volume per year. Approximately 40 reviews and 1,600 pages per year. ISSN: 0031-9333 (Print); eISSN: 1522-1210 (Online) Online Only Print & Online Print Only Domestic International Domestic International Tier 1 $475 $655 $700 Tiers 1– 5 $840 $895 Tier 2 580 765 805 Tier 3 690 855 910 Single Copies & Back Issues Tier 4 Custom Custom Custom Subscriber Non-Subscriber Tier 5 Custom Custom Custom $120 each $240 each tier definitions & custom pricing information on page 16 when available

Physiology

physiologyonline.org

Editor: Gary Sieck, PhD, Mayo Clinic Physiology publishes invited review articles written by leaders in their fields. These articles are peer reviewed and highlight major advances in the broadly defined field of physiology. The journal also publishes shorter articles that either highlight important emerging topics and technologies or explore differing points of view. The journal is a valuable tool for researchers, educators, and students. Published jointly by the International Union of Physiological Sciences (IUPS) and the American Physiological Society, Physiology has a 2016 Impact Factor of 6.076 and a cited half-life of 7.2 years. VOLUME 33 Published online as articles are ready and archived as bimonthly issues. Printed bimonthly—January, March, May, July, September, and November. One volume per year. Approximately 50 articles and 450 pages per year. ISSN: 1548-9213 (Print); eISSN: 1548-9221 (Online) Online Only Print & Online Print Only Domestic International Domestic International Tier 1 $295 $415 $435 Tiers 1– 5 $535 $565 Tier 2 360 485 505 Tier 3 420 545 575 Single Copies & Back Issues Tier 4 Custom Custom Custom Subscriber Non-Subscriber Tier 5 Custom Custom Custom $55 each $110 each tier definitions & custom pricing information on page 16 when available Advances in Physiology Education

advan.org

Editor: Douglas Curran-Everett, PhD, National Jewish Health Physiology instructors interested in educational research find Advances in Physiology Education to be an invaluable forum for learning and exchanging new ideas. All aspects of physiology education at academic levels are covered, including research reports, scholarly essays, and practical aids to teaching. Instructors will find information on curriculum design and implementation; new approaches to discovering the diversity of solutions to common physiological problems; creative approaches, including use of technology, to teaching physiology in large and small settings; and more. Advances in Physiology Education has a 2016 Impact Factor of 1.755 and a cited half-life of 8.7 years. VOLUME 42 Published online as articles are ready and archived as quarterly issues. Printed in December only. One volume per year. Approximately 90 articles and 550 pages per year. ISSN: 1043-4046 (Print); eISSN: 1522-1229 (Online) Online Only Print Only Single Copies & Back Issues Tiers 1–5 Domestic International Subscriber Non-Subscriber Free Worldwide $130 $155 $90 $180 tier definitions & custom pricing information on page 16 when available

Published by the American Physiological Society – Integrating the Life Sciences from Molecule to Organism THEPHYSIOLOGIST

Guyton Award Lecture July 2017 • Vol. 60/No. 4

Thomas Schmidt 2017 Arthur C. Guyton Physiology Educator of the Year Awardee Dinner with a

I certainly appreciate this opportunity to share Nobel Laureate with you some of my philosophy of teaching and briefly reflect on my own academic career asan Two of the Trainee Advisory Committee educator. I firmly believe that teaching is a special members, Ryan Downey (Teaching privilege, since it has given me the opportunity Section) and Ijeoma Obi (Water and to nurture, encourage, and motivate future Electrolyte Homeostasis Section), as generations of scientists, educators, and healthcare well as Jinae Roa (Porter Physiology providers. However, first and most importantly, Development Fellow, Eleanor Ison I want to convey to you how very honored I Franklin designee) had the pleasure of was to first be nominated for, and subsequently Thomas Schmidt having dinner with Dr. Louis Ignarro, selected, as the recipient of the 2017 Arthur C. the 1998 co-recipient Nobel Prize Guyton Educator of the Year Award. I know that winner in Physiology or Medicine for most physiologists appreciate the fact that not discovering the signaling role of nitric only was Dr. Guyton recognized as a highly respected cardiovascular physiologist with expertise in hypertension, but he was also the author of oxide in the cardiovascular system. This one of the world’s best-selling and most widely used textbooks of medical indeed was the highlight of the 2017 physiology. The fact that I have received an award that is named after this Experimental Biology conference. outstanding physiologist makes this recognition even more meaningful. During my career, I have been honored to receive a number of teaching The evening began with Dr. Ignarro awards, and those experiences have been very gratifying as well as giving his Nobel Prize award lecture humbling. However, for me personally, it is very important to never lose followed by a long line of trainees and The Physiologist sight of the fact that I truly enjoy teaching and helping students. Over 150 professors waiting to get an autograph years ago, President Abraham Lincoln said, “Don’t worry when you are and to have their picture taken with not recognized but strive to be worthy of recognition.” Those words have him. On our walk to dinner, I kept inspired me throughout my academic career and have been posted above my desk for many years. They serve as a daily reminder of how fortunate I have been, both in terms of the opportunities that I have had to contribute Continued on page 188 to the education of so many diverse students, as well as to contribute to both curriculum development at my own institution and to the educational programs offered by several national and international organizations with THIS ISSUE: clearly defined educational goals. 183 A Physiologist Does Second, I’d like to express my gratitude to the American Physiological Retirement Society (APS) for giving me numerous opportunities during my career to not only serve the Society in meaningful ways but to also promote the 189 APS 170th Business Meeting study of physiology at all educational levels. I hope that over the years I have made important contributions, not only by serving on the Education and Career Opportunities in Physiology Committees, but also as an 199 ACDP Survey Results invited faculty member for several APS Professional Skills Workshops and as faculty member/facilitator for the Institute on Teaching and Learning “Becoming an Effective Teacher” course. I certainly want to express my gratitude to the APS professional staff, not only for their encouragement 204 AAMC Compensation Survey and enthusiasm, but also for their confidence in my leadership abilities. I especially want to thank Marsha Matyas, Melinda Lowy, Brooke Bruthers, and Miranda Byse of the Education Office, and Marty Frank, APS Continued on page 185 the-aps.org the-aps.org/physiologist

Editor: Martin Frank, PhD, American Physiological Society The Physiologist, the newsletter of the APS, features articles on Society affairs and announcements, as well as articles of importance to today’s physiologist. The November and January issues may include abstracts of volunteered papers submitted for APS conferences. VOLUME 61 Published online bimonthly. Printed bimonthly—January, March, May, July, September, and November. One volume per year. ISSN: 0031-9376

Online Only Print Only Single Copies & Back Issues Tiers 1–5 Domestic International Subscriber Non-Subscriber Free Worldwide $235 $285 $30 $60 tier definitions & custom pricing information on page 16 when available Physiological Reports Physiological Reports

the-aps.org/prt

Editor: Susan Wray, PhD (term ends Dec. 31, 2017), University of Liverpool Thomas Kleyman, MD (term begins Jan. 1, 2018), University of Pittsburgh Physiological Reports is an open access journal published jointly by the American Physiological Society and The Physiological Society. Physiological Reports publishes peer-reviewed research across all areas of basic, translational, and clinical physiological and allied disciplines. As a collaboration between APS and The Physiological Society, Physiological Reports is in a unique position to serve the international physiology community through quick time to publication, while upholding a quality standard of sound research that constitutes a useful contribution to the field. The journal is published on behalf of the societies by Wiley-Blackwell and is now indexed in MEDLINE. VOLUME 6 Published online as bimonthly issues. One volume per year. Approximately 380 articles. ISSN: 2051-817X

Comprehensive Physiology

comprehensivephysiology.com Editor: David Pollock, PhD, University of Alabama at Birmingham Comprehensive Physiology is the most authoritative and comprehensive collection of physiology information that has ever been assembled. Its starting point is more than 30,000 pages and 34 volumes of content from APS’ renowned Handbook of Physiology series, which is presented now for the first time in a dynamic online format. With the click of a mouse, researchers can instantly jump to expert reviews presenting the most current science in physiology. Comprehensive Physiology includes the latest discoveries and methods, as well as insights into what new research is needed and where the field is heading. The journal features regular issues delivering thousands of pages of new information every year. New material will not only update and expand upon the Handbook of Physiology’s classic content but also add fresh, expertly written reviews to present new and emerging topics in physiology. Comprehensive Physiology covers all of the field’s subdisciplines, including neurophysiology, heart and circulatory physiology, applied physiology, gastrointestinal and liver physiology, endocrinology and metabolism, renal physiology, and more. A valuable scientific resource for your library, Comprehensive Physiology offers new and updated materials published in a quarterly serial format. The journal is indexed in PubMed/MEDLINE, Scopus, and Clarivate Analytics Web of Science. Comprehensive Physiology has a 2016 Impact Factor of 6.949 and a cited half-life of 3.8 years. VOLUME 8 Published online as quarterly issues. One volume per year. Approximately 410 articles. ISBN: 9780470650714 JOURNAL 100 YEARS of science LEGACY CONTENT online

The Journal Legacy Content of the American Physiological Society is an online package of 100 years of scientific research from 13 APS journals. It can be purchased separately at a one-time charge.

Legacy Content is a separate program from the Subscription Program in that you pay once for perpetual access. The package includes content from 13 APS journals (see chart below). The content goes back to the first issue of each journal—including the first volume, the American Journal of Physiology, published in 1898. Legacy Content is viewable as fully searchable scanned images of the printed pages. Journal Titles Legacy Content Dates Journal of Applied Physiology Jan. 1948 – Sept. 1996 Journal of Neurophysiology Jan. 1938 – Dec. 1996 American Journal of Physiology (AJP) Jan. 1898 – Dec. 1976 AJP–Cell Physiology Jan. 1977 – Sept. 1997 AJP–Endocrinology and Metabolism Jan. 1977 – Sept. 1997 AJP–Gastrointestinal and Liver Physiology Jan. 1980 – Sept. 1997 AJP–Heart and Circulatory Physiology Jan. 1977 – Sept. 1997 AJP–Lung Cellular and Molecular Physiology Aug. 1989 – Sept. 1997 AJP–Regulatory, Integrative and Comparative Physiology Jan. 1977 – Sept. 1997 AJP–Renal Physiology Jan. 1977 – Sept. 1997 Physiological Reviews Jan. 1921 – Dec. 1997 Physiology Feb. 1986 – Dec. 1997 Advances in Physiology Education June 1989 – Nov. 1997

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BOOK MONOGRAPH SERIES

APS has collaborated with Springer to digitize 34 book titles previously published in the book monograph series including the following popular series, Methods in Physiology, Physiology in Health and Disease, and Perspectives in Physiology (formerly People and Ideas). Additionally, APS and Springer will be publishing new titles.

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Overload-mediated skeletal muscle hypertrophy is not impaired by loss of myofiber STAT3 Cell Physiology

Overload-mediated skeletal muscle hypertrophy is Sodiumnot storage in human tissues is mediated by glycosaminoglycan expression impaired by loss of myofiber STAT3 Renal Physiology The human coronary vasodilatory response to Cell Physiology acute mental stress is mediated by neuronal Overload-mediated skeletal nitric oxide synthase Heart and Circulatory Physiology muscle hypertrophy is not impaired by loss of FREE myofiber STAT3 A novel role for primary cilia in airway remodeling Cell Physiology Lung Cellular and Molecular Physiology

Although the signal pathways mediating muscle protein synthesis and degradation are well characterized, the transcriptional processes modulating skeletal muscle mass and adaptive Cerebral oxygenation and regional cerebral growth are poorly understood. Recently, studies perfusion responses with resistance breathing 2-month in mouse models of muscle wasting or acutely exercised human muscle have suggested a potential during central hypovolemia role for the transcription factor, signal transducer and activator of transcription 3 (STAT3), in adaptive Regulatory, Integrative and Comparative Physiology growth. Hence, in the present study we sought to define the contribution of STAT3 to skeletal muscle adaptive growth. In contrast to previous work, two different resistance exercise protocols did not change STAT3 phosphorylation in human skeletal muscle. To Development of a reliable, automated screening directly address the role of STAT3 in load-induced system to identify small molecules and biologics (i.e. adaptive) growth, we studied the anabolic effects of 14 days of synergist ablation (SA) in skeletal that promote human β cell regeneration muscle-specific STAT3 knockout (mKO) mice and Endocrinology and Metabolism their floxed, wild type (WT) littermates. Plantaris muscle weight and fibre area in the non-operated leg (Control; CON) was comparable between genotypes. As expected, SA significantly increased plantaris online weight, muscle fibre cross sectional area and anabolic Roles of autophagy and metabolism signaling in WT mice, although interestingly, this induction was not impaired in STAT3 mKO mice. in pancreatic cancer cell adaptation to Collectively, these data demonstrate that STAT3 is not required for overload-mediated hypertrophy in environmental challenges trial mouse skeletal muscle. Gastrointestinal and Liver Physiology