2018 Department of Ophthalmology Chair Report

SAVE THE▼ DATE Department of 200 Ophthalmology Years www.NYEE.edu Anniversary SPECIALTY REPORT | FALL 2018 www.NYEE.edu Celebration Join us for 200 Years and Counting: Bicentennial Cocktail Celebration October 15, 2020 Research Breakthrough: The Plaza 768 5th Avenue Gene Transfer New York, NY Therapy Restores 200 Years and Counting: Ophthalmology Vision in Mice Symposium October 16, 2020 Stay tuned for details on tickets and registration information. Cover image: Slice of a central retina section showing all layers (ONL, INL, GCL). Red indicates rod photoreceptors, located in outer nuclear layer (ONL). Green indicates Müller glial cells, whose cell bodies are located in inner nuclear layer (INL), and their branches across all three layers. Dark blue indicates the nucleus of all cells in three layers (GCL). Icahn School of Medicine at Medical Directors Neuro-Ophthalmology Uveitis and Ocular Immunology Mount Sinai Departmental Mark Kupersmith, MD Douglas Jabs, MD, MBA Avnish Deobhakta, MD Leadership System Chief, System Chief, Uveitis and Ocular Medical Director, NYEE - Neuro-Ophthalmology, Immunology, MSHS James C. Tsai, MD, MBA East 85th Street MSHS President, NYEE Stephanie Llop, MD System Chair, Department of Robin N. Ginsburg, MD 3 Message From the System Chair of the DepartmentValerie Elmalem, of Ophthalmology MD Sophia Saleem, MD Ophthalmology, MSHS Medical Director, NYEE- Joel Mindel, MD East 102nd Street Louis4 R. Pasquale,Breaking MD New Ground in Gene Transfer Therapy to Restore Vision Affiliated Leadership Ocular Oncology Site Chair, Department of Gennady Landa, MD Paul Finger, MD Ebby Elahi, MD, MBA Ophthalmology, MSH and MSQ Medical Director, NYEE- 6 This i-Doctor Is Transforming the Field of Ophthalmology President, NYEE/MSH System Vice Chair, Translational Williamsburg and Tribeca Ophthalmic Pathology Ophthalmology Alumni Ophthalmology Research, MSHS Jodi Sassoon, MD Society Kira Manusis, MD Inside Feature Site Chair, Pathology, NYEE Medical Director, NYEE- Paul A. Sidoti, MD Robert Fischer, MD Midwood Site Chair, Department • of Imaging Is a Pivotal Part of NYEE's Rich HistoryNada Farhat, MD Director of Ophthalmology, Ophthalmology, NYEE Alan Friedman, MD Elmhurst Hospital Paul A. Sidoti, MD System Chief, Glaucoma, MSHS Codrin Iacob, MD Medical Director, NYEE- • What Do Retinal Imaging and the Hubble Telescope Share? David Goldman, MD East 14th Street Douglas Fredrick, MD Oculoplastic and Medical Director, NYEE-West The Unique Technology of Adaptive Optics. Deputy Chair for Education, MSHS Reconstructive Surgery Palm Beach Angie E. Wen, MD System Chief, Pediatric Robert Della Rocca, MD • An UnprecedentedMedical Look Director, at NYEE- Acute Solar Retinopathy Ophthalmology and Strabismus, System Chief, Oculoplastic Michelle Rhee, MD Columbus Circle MSHS and Reconstructive Surgery, Associate Director of • Targeting Macular Degeneration ThroughMSHS State-of-the-Art ImagingOphthalmology, Elmhurst Douglas A. Jabs, MD, MBA Clinical Divisions at Hospital Deputy Chair for Research, MSHS Mount Sinai Health David Della Rocca, MD Director, Eye and Vision • ResearchAn NYEE-Mount System Sinai Faculty Eye Stroke Practices Protocol Monica Saves Dweck, a YoungMD Woman’s Sight Institute, MSHS Valerie Elmalem, MD Cornea, External Diseases, Alexander Rabinovich, MD • NYEE Diagnostic Imaging Advances: 198 Years of Innovation Salvatore Loiacono, Jr. MPA and Refractive Surgery Harsha Reddy, MD NYEE = New York Eye and Ear John Seedor, MD Deputy Chair for Finance and Infirmary of Mount Sinai Administration, MSHS System Chief, Cornea and Pediatric Ophthalmology 9 NYEE Uses a Rare Retinal Transplant to Close a Patient’s Macular Hole MSHS = Mount Sinai Health System Vice President for Ophthalmology External Diseases, MSHS and Strabismus MSH = The Mount Sinai Hospital Services, NYEE Douglas Fredrick, MD MSQ = Mount Sinai Queens 11 A Clinical Trial SeeksDavid to Ritterband,Boost Patient MD Satisfaction System By Chief, Making Pediatric Intravitreal Injections Less Painful Richard B. Rosen, MD System Chief, Refractive Ophthalmology and Deputy Chair for Clinical Affairs, MSHS Surgery, MSHS Strabismus, MSHS Vice12 Chair and DirectorNew of Pediatric Ophthalmic Ophthalmology Fellowship Program Is Broadening NYEE’s Patient Services Research, NYEE Sumayya Ahmad, MD Tamiesha Frempong, MD, Priti Batta, MD MPH Christopher14 T. Spina,Faculty MS News: PromotionsAnita Gupta, MD Edward Raab, MD Senior Vice President and Chief Noga Harizman, MD Steven Rosenberg, MD Operating15 Officer,Faculty NYEE News: AppointeesRichard Koplin, MD Erin Walsh, MD Kira Manusis, MD Tamiesha Frempong, MD, MPH Angie Wen, MD Primary Care Vice16 Chair for DiversityDepartment and Inclusion, of Ophthalmology at a Glance Ophthalmology/Optometry MSHS Eye Trauma Karen Hendler-Goldberg, MD John Aljian, MD Bessie Abraham, OD Sandra K. Masur, PhD Ronald Gentile, MD Jared Hayashi, OD Vice Chair for Mentoring, MSHS Harsha Reddy, MD Vanessa Hernandez, OD Caitlin Morrison, OD Donna J. Gagliuso, MD Glaucoma Elena Schmidt, OD Affiliated Teaching Residency Program Director, MSH Paul Sidoti, MD Institutions System Chief, Glaucoma, Retina James J. Peters VA Anita Gupta, MD MSHS Nazanin Barzideh, MD Medical Center Residency Program Director, NYEE Avnish Deobhakta, MD 130 West Kingsbridge Road Director, Comprehensive Nisha Chadha, MD Robin Ginsburg, MD Bronx, NY 10468 Service, NYEE Donna Gagliuso, MD Meenakashi Gupta, MD NYC Health+Hospitals/Elmhurst Noga Harizman, MD Gennady Landa, MD 79-01 Broadway Paul S. Lee, MD Tsontcho Ianchulev, MD Jessica Lee, MD Queens, NY 11373 Associate Residency Program Nathan Radcliffe, MD Gareth Lema, MD, PhD Mount Sinai Union Square Director, MSH Robert Ritch, MD Richard Rosen, MD 10 Union Square East Chief of Ophthalmology, James J. Tania Tai, MD R. Theodore Smith, MD, PhD New York, NY 10003 Peters VA Medical Center James Tsai, MD, MBA Kateki Vinod, MD 173 MESSAGE FROM THE SYSTEM CHAIR OF THE DEPARTMENT OF OPHTHALMOLOGY James C. Tsai, MD, MBA The New York City metropolitan region deserves to have one of the world’s leading centers for ophthalmology and vision research. I am delighted to highlight the many steps that New York Eye and Ear Infirmary of Mount Sinai (NYEE) has taken over the past year to move ever closer to that goal. Rather than rest on our laurels as the oldest specialty hospital in America, founded in 1820, we are focused on extending our longstanding reputation for clinical excellence to that of innovation and development of exciting new treatments and approaches for complex blinding eye diseases. Recruiting top scientific talent is an integral part of our overall strategy, as evidenced by our recent appointment of Louis Pasquale, MD, FARVO, as Vice Chair of Translational James C. Tsai, MD, MBA, President, New York Eye and Ear Infirmary of Mount Sinai, Ophthalmology Research for the Mount Sinai System Chair, Department of Ophthalmology, Delafield-Rodgers Professor of Ophthalmology, Health System and Site Chair of Ophthalmology Icahn School of Medicine at Mount Sinai at The Mount Sinai Hospital. Dr. Pasquale, who has gained international recognition for his research, will focus on integrating NYEE into the cutting-edge, Program. Together, these programs are helping to ensure we work interdisciplinary clinical and translational research network of synergistically with such well-established academic departments the Icahn School of Medicine at Mount Sinai. Our commitment to and research centers at Mount Sinai as The Friedman Brain education complements our research initiatives, which is one of the Institute, the Icahn Institute for Genomics and Multiscale Biology, reasons we have recruited Douglas Fredrick, MD, as Deputy Chair and The Black Family Stem Cell Institute. for Education in the Department of Ophthalmology and System Chief of Pediatric Ophthalmology. Among Dr. Fredrick’s priorities Our research and clinical efforts rest on another powerful pillar will be consolidating and combining the already outstanding with a rich history at NYEE: imaging. We are home to one of the ophthalmology residency programs at NYEE and The Mount Sinai leading imaging laboratories in the world under the direction Hospital into one of the largest residency programs in the nation. of Richard Rosen, MD, Vice Chair and Director of Ophthalmic In addition, our pursuit of clinical excellence is highlighted by the Research at NYEE. As the articles in this Specialty Report appointment of Paul Sidoti, MD, as Site Chair of Ophthalmology illustrate, this extraordinary imaging team, working with the most at NYEE. sophisticated equipment anywhere, is allowing us to explore and understand diseases like glaucoma and macular degeneration at a The many accomplishments of our researchers and clinicians this level we never could before. New York Eye and Ear Infirmary past year underscore the breadth of NYEE’s capabilities—and their enormous potential. For example, a team of scientists led As we approach our bicentennial in 2020, it’s important to note (Founded August, 1820) by Bo Chen, PhD, who heads up our Ocular Stem Cell Program, that 2018 marks the centennial of The American Journal of 1 restored vision in congenitally blind mice by activating and Ophthalmology (AJO). A recent article in that journal describes reprogramming retinal stem cells. This breakthrough process, how the histories of AJO and NYEE have been inextricably described in the August 15, 2018 issue of Nature, could unveil a bound. Indeed, in its venerable role as recorder of institutional promising and long-awaited

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