Syst. Biol. 67(1):1–13, 2018 © The Author(s) 2017. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email:
[email protected] DOI:10.1093/sysbio/syx064 Advance Access publication July 13, 2017 Genomic Signature of an Avian Lilliput Effect across the K-Pg Extinction ,∗, , , JACOB S. BERV1 † AND DANIEL J. FIELD2 3 † 1Department of Ecology & Evolutionary Biology, Cornell University, 215 Tower Road, Ithaca NY, 14853, USA; 2Department of Geology & Geophysics, Yale University, 210 Whitney Avenue New Haven, CT, 06511, USA; and 3Department of Biology and Biochemistry, Milner Centre for Evolution, University of Bath, Building 4 South, Claverton Down, Bath, BA2 7AY, UK ∗ Correspondence to be sent to: Department of Ecology & Evolutionary Biology, Cornell University, Ithaca, NY, USA; E-mail:
[email protected]. †Jacob S. Berv and Daniel J. Field contributed equally to this work. Received 12 February 2017; reviews returned 03 July 2017; accepted 05 July 2017 Associate Editor: Simon Ho Abstract.—Survivorship following major mass extinctions may be associated with a decrease in body size—a phenomenon called the Lilliput Effect. Body size is a strong predictor of many life history traits (LHTs), and is known to influence demography and intrinsic biological processes. Pronounced changes in organismal size throughout Earth history are therefore likely to be associated with concomitant genome-wide changes in evolutionary rates. Here, we report pronounced heterogeneity in rates of molecular evolution (varying up to ∼20-fold) across a large-scale avian phylogenomic data set and show that nucleotide substitution rates are strongly correlated with body size and metabolic rate.