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General Pathology Lectures

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General Pathology Lectures UNIVERSITY OF ILLINOIS COLLEGE OF MEDICINE AT URBANA-CHAMPAIGN PATHOLOGY - VOLUME I 2013 - 2014 PATHOLOGY TEACHING FACULTY LIST William Albers, MD Farah Gaudier, MD Ramesh Ramanathan, MD Peoria Department of Pediatrics Dept. of Pathology [email protected] 420 N.E. Glen Oak, Suite 304 Carle Physician Group Peoria, IL 61603 [email protected] Michael Schneider, MD Phone: (309) 655-3453 Dept. of Pediatrics/Genetics [email protected] Nasser Gayed, MD Carle Physician Group Dept. of Med. Info. Sciences [email protected] Jerome Anderson, MD 190 Medical Sciences Bldg Department of Pathology 506 South Mathews Avenue William Scott, MD MPH McDonough District Hosp. Urbana, IL 61801 Clinical Assistant Professor McComb, IL 61455 [email protected] Occupational medicine Phone: (309) 837-2368 Carle Physician Group [email protected] Nicole Howell, MD [email protected] Dept. of Pathology Brett Bartlett, MD Carle Physician Group Richard Tapping, PhD Dept. of Pathology [email protected] Associate Professor. SBL Health Centre Dept. of Microbiology Mattoon, IL 61938 Zheng George Liu, MD [email protected] [email protected] Dept. of Pathology Carle Physician Group Teaching Assistant Frank Bellafiore, MD 602 West University Avenue Brent Beenders, PhD Dept. of Pathology Urbana, IL 61801 [email protected] Carle Physician Group [email protected] 602 West University Avenue Urbana, IL 61801 Naveen Manchanda, MD Pathology Office [email protected] Indiana Univ. Sch. of Medicine Jackie Newman Dept. of Hematology/Oncology Phone: (217) 244-2265 Allan Campbell, MD 525 Barnhill Drive [email protected] Dept. Of Pathology Indianapolis, IN 46202 UICOM Peoria IL [email protected] [email protected] Steve Nandkumar, M.D. Gregory Freund, MD Pathology Course Director Head, Dept. of Pathology 249 Medical Sciences Building 190 Medical Sciences Building 506 South Mathews Avenue 506 South Mathews Avenue Urbana, IL 61801 Urbana, IL 61801 [email protected] [email protected] Page 2 Pathology M-2 Introduction INTRODUCTION Pathology – study of the essential nature of diseases and the structural and functional changes produced by them. ( Pathos= suffering; ologos = study) Pathology consists of two major subdivisions. 1. ANATOMIC PATHOLOGY (AP) This covers surgical pathology, cytopathology, and autopsy pathology. 2. CLINICAL PATHOLOGY (CP) This deals with analyses of body fluids and tissues and involves various disciplines of microbiology, serology, clinical chemistry, hematology, transfusion medicine, cytogenetics, etc. General and systemic pathology (AP) and clinical laboratory sciences (CLS) will be taught throughout the year. General pathology emphasizes cellular and molecular biology, biochemistry, and immunology as they relate to the pathogenesis of disease. Systemic pathology deals with diseases of various “organs and systems”. The clinical laboratory sciences (CLS) course deals with laboratory medicine involving lab testing. It is that branch of clinical pathology that applies scientific laboratory methods relevant to patient care, health promotion and disease prevention. The three pillars of evidence-based medicine are: A. What are the results? B. Are the results valid? C. How are the results applicable to patient care? The CLS course will attempt to answer the above utilizing a clinical “case format”. The significance and implications of lab testing, frequency of tests, turn-around-time (TAT), limitations of lab data, quality control and cost effectiveness will be discussed. The overall approach is to emphasize Lab Testing and how it relates to CLINICAL DIAGNOSIS AND MANAGEMENT. RECOMMENDED TEXTBOOKS 1. Robbins and Cotran Pathologic Basis of Disease by Kumar, Abbas, Fausto, and Aster , 8th edition. HIGHLY RECOMMENDED. 2. Robbins Basic Pathology by Kumar, Abbas, Foster, 9th edition. For the CLS course: - NEED NOT PURCHASE 1. Henry’s Clinical Diagnosis and Management by Laboratory Methods by McPherson and Pincus, 22nd edition, Saunders Publishing Company 2. Interpretation of Diagnostic Tests by Jacques Wallach, M.D., 8th edition, Lippincott, Williams, and Wilkins Publishers (cost about $65.00). Pathology M-2 – Introduction Page 3 3. Widmann’s Clinical Interpretation of Lab Tests, 11th edition, by Ronald Sacher, M.D., and Richard McPherson, M.D. EXAMINATIONS There will be eight interim ( part of integrated exams.) and one final examination. The interim examinations are generated within the department; the final examination is the NBME subject ( shelf) examination in pathology supplied and scored by the National Board of Medical Examiners. Note that the NBME reports a percent correct score along with a scaled score. It is this score that will be used in the final weighting described below. All the questions on the interim exams are multiple choice. There are approximately 80 questions on Foundations integrated examination 1, and roughly 4 questions per teaching/learning session on the other exams. for a total of about 315 MCQs. These numbers are subject to change as thought appropriate by the faculty. Questions on the laboratory sessions will be incorporated as pictures (images) into the examination when applicable. Each of the interim examinations will be weighted in proportion to the number of questions on that examination. Together the interim examinations will constitute 75%, and the final examination (shelf exam – 125 multiple choice questions) 25% of the total weighted score. Should a student fail to achieve a minimum passing level (MPL) for the examination series, the M-2 guidelines as determined by the Office of Student Affairs (including remedial work and a make-up examination) will be followed. The pathology department reserves the right to determine the type of make-up examination. NOTE: UI COM HAS IMPLEMENTED A “FLOATING MPL” SYSTEM DETAILS OF WHICH MAY BE OBTAINED FROM THE OFFICE OF ACADEMIC AFFAIRS. SUFFICE TO SAY THAT THE MPL WILL BE BETWEEN 60 – 65%. Please note that: 1. Students undergoing remediation must take and pass the pathology make-up exam before being allowed further progress in their academic work. 2. The pathology make-up exam will be scheduled on Wed. May 21st 2014 (exact time, place, and type of exam. will be announced later). 3. Delays will not be permitted. Extenuating circumstances will be considered by the Pathology Department on a case by case basis. If you have any questions regarding the curriculum, the course, or the examinations, do not hesitate to contact Dr. Gregory Freund, Head, Department of Pathology, Dr. Steve Nandkumar, Pathology Course Director and Coordinator, or Brent Beenders PhD, Pathology Teaching Assistant. Faculty Department of Pathology “Be not the first by whom the new are tried Nor yet the last to lay the old aside.” Alexander Pope Page 4 Pathology M-2 Introduction UNIVERSITY OF ILLINOIS COLLEGE OF MEDICINE Department of Pathology At Urbana-Champaign 190 Medical Sciences Building (MC-714) 506 S Mathews Urbana, IL 61801 August, 2013 Dear Second Year Medical Students: Congratulations on successfully completing the M-1 year and welcome to the M-2 year! As your teaching assistant for Pathology, I will set up teaching sessions and office hours for all M-2 students. Although the sessions are not mandatory, they are highly recommended. The time for our meetings will be determined after school begins and may vary from week to week as we try to find times that work with both your schedules and mine. Most students find pathology to be the most challenging course they have taken so far in medical school. The course content is large and you are required to know the material at a surprising level of detail. I will be providing practice questions, and I hope to take away some of the stress of wondering what the level of questioning will be like. As far as book resources go, the recommended book for the course is “Big” Robbins (Pathologic Basis of Disease; ISBN 978-1-4160-3121-5). Take care not to confuse this book with “Baby” Robins (Basic Pathology; ISBN 978- 1-4377-1781-5), which is smaller because it removes all of the explanatory text and is often much more difficult to understand than “Big” Robbins. Robbins Review of Pathology (ISBN 0721682596) is a question book that I found to be almost indispensable when I took the course. Past students have also recommended Pretest Pathology. You don’t need to buy them as long as you don’t mind sharing the library copies. I think the questions in these books may be a little harder than a typical exam question, but they are representative of the level of difficulty of questions on the NBME pathology shelf-exam that you will take in the spring. Q banks from Kaplan and USMLE World are useful. There are various pathology resources available on the internet. One that I found to be particularly useful was Webpath (http://www-medlib.med.utah.edu/WebPath/webpath.html). This site features images and a large set of review questions. Also, the GRIPE website http://peir.net is available for viewing digitized images. One final note on books: BRS Pathology is a quick review book for USMLE or for organizing your thoughts, but the level of detail in this book may not be sufficient for you to pass the pathology course. Please feel free to contact me by e-mail ([email protected]) with any questions, comments, concerns, or suggestions as the year goes by. Brent Beenders PhD GOALS AND OBJECTIVES Department of Pathology ( please visit the COM M2 web site and go to learning objectives;this password protected site will give you the lecture titles and their corresponding objectives, compiled by pathology faculty members at all four sites) Pathology Course Goals and Objectives By the end of the course, successful students will achieve the level of competence expected of a medical student completing the M2 year, studying for USMLE Step 1, and preparing for the M3 year and patient care responsibilities through the following broad goals and objectives. Specific learning objectives for large and small groups are included at the time of each section.
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