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^Jfehington University in St Louis Oct. 8, 2009 record.wustl. Sleep loss linked to increase in Alzheimer's plaques

BY MICHAEL C. PURDY ment of Neurology. "The results also suggest that Chronic sleep deprivation in a we may need to prioritize treating mouse model of Alzheimer's sleep disorders not only for their disease makes Alzheimer's many acute effects but also for brain plaques appear earlier and potential long-term impacts on more often, School of Medicine brain health," he said. researchers reported online in Holtzman's laboratory uses a Science Express. technique called in vivo microdi- Neurodegenerative disorders alysis to monitor levels of amyloid like Alzheimer's disease and beta in the brains of mice geneti- Parkinson's disease often disrupt cally engineered as a model of sleep. The new findings are some Alzheimer's disease. Amyloid beta of the first indications that sleep is a protein fragment that is the loss could play a role in the genesis principal component of Alzheim- of such disorders. er's plaques. The researchers also found that Jae-Eun Kang, Ph.D., a post- orexin, a protein that helps regu- doctoral fellow in Holtzman's lab, late the sleep cycle, appears to be noticed that brain amyloid beta Transcending bigotry through art, friendship A dialogue by alumni Michael Adams (left) directly involved in the increase in levels in mice rose and fell in and Gyo Obata drew a standing room-only crowd to Steinberg Hall Oct. 2.Their talk, titled brain plaques. association with sleep and wake- "Remembering the Internment," focused on the friendship between their famous fathers, the "Orexin or compounds it inter- fulness, increasing in the night, photographer Ansel Adams and the painter (pictured), and how both families were acts with may become new drug when mice are mostly awake, and impacted by the U.S. government's internment of Japanese-Americans during World War II. The ...... decreasing during the day, when event was organized by the Center for the Study of Ethics & Human Values as part of the semes- targets for treatment of Alz- ter-long series "Ethnic Profiling: A Challenge to Democracy." Works by Ansel Adams and Chiura heimer's disease," said senior au- they are mostly asleep. Obata also are included in the exhibition "A Challenge to Democracy: Ethnic Profiling of Japanese thor David M. Holtzman, M.D., A separate study of amyloid Americans During World War II," on view in the Teaching Gallery of the Mildred Lane Kemper Art the Andrew and Gretchen Jones beta levels in human cerebrospinal Museum through Jan. 4,2010. Professor and chair of the Depart- See Sleep, Page 6 Forecast for discovered exoplanet: cloudy with a chance of pebbles

BY DIANA LUTZ atmosphere is made up of the ingredients of Jupiter, which has 300 times the mass of miles, 23 times less than the distance be- rocks, and when a front moves in, pebbles Earth.) tween the parboiled planet Mercury and our So accustomed are we to the sunshine, condense out of the air and rain into lakes of COROT-7b, on the other hand, is less Sun. rain, fog and snow of our home planet molten lava below. than twice the size of Earth and only five Because the planet is so close to the star, that we find it next to impossible to imagine The work, by Laura Schaefer, research times its mass. it is gravitationally locked to it in the same a different atmosphere and other forms of assistant in the planetary chemistry labora- COROT-7b was the first planet found way the moon is locked to Earth. One side precipitation. tory in the Department of Earth & Planetary orbiting the star COROT-7, an orange dwarf of the planet always faces its star, just as one To be sure, Dr. Seuss came up with a Sciences in Arts & Sciences, and Bruce in the constellation Monoceros, or the side of the moon always faces Earth. green, gluey substance called oobleck that Fegley Jr., Ph.D., professor of earth and Unicorn. (This priority is designated by the This star-facing side has a temperature of fell from the skies and gummed up the planetary sciences, appeared in the Oct. 1 letter b.) about 2,600 Kelvin (4,220 degrees Fahren- Kingdom of Didd, but it had to be conjured issue of The Astrophysical Journal. Using the data from both planets, they heit). That's infernally hot — hot enough to up by wizards and clearly was a thing of Astronomers have found nearly 400 were able to calculate that COROT-7b has vaporize rocks. The global average tempera- magic. extra-solar planets, or exoplanets, in the an average density about the same as Earth's. ture of Earth's surface, in contrast, is only Not so with the atmosphere of COROT- past 20 years. But because of the limitations This means it is almost certainly a rocky about 288 Kelvin (59 degrees Fahrenheit). 7b, an exoplanet discovered last February by of the indirect means by which they are planet made up of silicate rocks like those in The side in perpetual shadow, on the the COROT space telescope launched by the discovered, most are Hot Jupiters, chubby Earth's crust, Fegley said. other hand, is positively chilly at 50 Kelvin French and European space agencies. gas giants — as large or larger than Jupiter Not that anyone would call it Earth-like, (-369 degrees Fahrenheit). According to models by Washington — orbiting close to their parent stars. (More much less hospitable to life. The planet and Perhaps because they were cooked off, University scientists, COROT-7b's than 1,300 Earths could be packed inside its star are separated by only 1.6 million See Exoplanet, Page 6

Nine years of helping needy with Give Thanks Give Back

BY NEIL SCHOENHERR St. Louis-area residents struggling to overcome poverty. Now in its ninth year, Washington University's As the holiday season approaches, the news- Give Thanks Give Back campaign again will paper publishes the personal case stories of 100 help make the holiday season brighter for needy families or individuals. Although each of the St. Louis area families. 10,000 cases will receive some assistance, only a The annual event begins at 10 p.m. Thursday, small percentage of families are "adopted," Oct. 8, with a kick-off party at Ursa's Cafe in the meaning that an individual or group agrees to South 40. In addition, students will be manning buy gifts, clothing, household appliances or tables and handing out information outside the other requested items for the family. Danforth University Center from 11 a.m.-l p.m. Members of the University community Tuesday, Oct. 13, and Wednesday, Oct. 14. normally adopt around 120 families each year, "Give Thanks Give Back is a fun and afford- which amounts to more than 300 individuals. able way for students, faculty and staff to help "All of these families live in the area and have out the St. Louis community during the holiday fallen on hard times due to a layoff or injury," season," said senior Lynn Wilkie, a psychology Wilkie said. "We connect students and faculty major in Arts & Sciences and co-chair of this to the families who need assistance, and then year's Give Thanks Give Back student group. the sponsors go shopping for clothing, house- Give Thanks Give Back supports a group hold supplies or educational toys, depending on called "100 Neediest Cases," a joint project of the needs of the family. the St. Louis Post-Dispatch and the United Way. "It's a great way to locally make a difference During the holiday season, the 100 Neediest in someone's life, and we are always amazed and Students help wrap gifts last November for needy families with the annual Cases identifies more than 10,000 cases of See Give Back, Page 2 Give Thanks Give Back campaign. 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS

Creating a culture of integrity BY KURT MUELLER evidenced by corporate scandals, doping by professional athletes David Callahan, Ph.D., public and plagiarizing. He puts the policy activist and scholar of blame on the ruthlessly competi- academic integrity, will present tive economic climate of the past "Creating a Culture of Integrity" two decades and claims that the at 11 a.m. Thursday, Oct. 15, in "winning" class has enough mon- Graham Chapel. ey and clout that they can cheat His talk is the keynote address without consequences, while the of The Center for Academic "anxious" class believes that cheat- Integrity's 18th Annual Inter- ing is the only way to succeed in a national Conference (see below) winner-take-all world. and is being co-spon- Callahan is a co- sored by the Assembly founder of Demos, a Series and the Center public policy center based for Ethics and Human in New York. It is a multi- Values. It is free and issue national organiza- open to the public. tion that combines re- In his 2006 book, search, policy develop- "The Moral Center: ment and advocacy to How We Can Reclaim influence public debates Our Country from Die and catalyze change. Hard Extremists, Rogue Callahan serves as Corporations, Holly- Callahan Demos' international wood Hacks and Pretend program director and Patriots," Callahan examines senior fellow. seven of our most polarizing He earned a bachelor's degree conflicts — family, sex, media, from Hampshire College and a crime, work, poverty and patrio- doctorate in politics from tism — and presents unexpected Princeton University. Practice makes perfect Mark Bagby (center), University emergency coordinator, monitors a solutions that lay out a new road A series of free campus events fire drill Sept. 29 at Simon Hall as students, faculty and staff gather outside the Francis Field map to the American center. precedes the lecture, including gates.The drill was held to test Olin Business School's emergency planning efforts and in "The Moral Center" is a follow- panel discussions on the state of anticipation of this week's National Fire Prevention Week Oct. 5-9. "Olin has been working hard on up text to Callahan's 2004 book integrity at WUSTL (7:30 p.m. its emergency planning, and this drill was a successful test of its planning efforts," Bagby said. "The Cheating Culture: Why Monday, Oct. 12, in the Danforth For more information about what to do in case of a fire on campus, visit emergency.wustl.edu/ Americans Are Doing Wrong to University Center, Room 276); wheretogo/fire.html. Get Ahead." intellectual property (5:30 p.m. If we were given the opportu- Tuesday, Oct. 13, in the Danforth nity to cheat on our taxes or to University Center, Room 276); illegally hook up to our neighbor's and why employers and graduate Trustees hear reports on admissions, construction, cable, Callahan thinks most of us schools look at integrity, not would do so. perfection (7 p.m. Wednesday, financial issues and new scholarship initiative In "The Cheating Culture," Oct. 14, in Umrath Hall Lounge). Callahan wrote that cheating has For more information, visit The fall meeting of the Board assembly space for residential announcement of a new effort to risen in the past 20 years as academicintegrityweek.wustl.edu. of Trustees Oct. 2 featured college students. secure support for scholarships reports on the status and More good news was the re- called "Opening Doors to the Integrity conference here Oct. 16-18 progress of the University, includ- cent announcement of a LEED Future: The Scholarship Initiative ing a report from Chancellor Silver rating from the USGBC for for Washington University." Washington University will Arts & Sciences, who died in Mark S. Wrighton regarding the Village East student apartment Trustee Vice Chair John host The Center for 2004 of metastatic neuro- admissions, construction, finan- building. Other buildings that McDonnell, retired chairman of Academic Integrity's 18th eqdocrine cancer. She was 47. cial issues, appointments and a have earned certification are the board of McDonnell Douglas Annual International Conference Johnson, a WUSTL alumna, new scholarship initiative. LEED Gold for the Danforth Corp., reported specific details Oct. 16-18. The conference is credited with leading the In his remarks, Wrighton University Center and LEED for on the initiative that seeks to theme is "Creating a Culture of effort to develop a campus-wide noted the continuing success of Seigle Hall and the Earth & raise $150 million for scholarships Integrity: Research and Best academic integrity code at the undergraduate admissions Planetary Sciences Building. A and fellowships, including his Practices." WUSTL when she came to program in attracting the most just completed total renovation of $2 million challenge grant intend- Several hundred students, work here in 1989 as special academically talented class in the century-old Busch Hall also may ed to encourage new and in- faculty and staff from around the assistant to then-Chancellor University's history, numbering receive LEED certification. creased annual scholarships for world will discuss the practice William H. Danforth. She dealt about 1,500 students selected At the Tyson Research Center both undergraduate and graduate and philosophy of academic with a wide variety of campus from more than 23,000 applicants. in west St. Louis County, the new students. Chairing the initiative is integrity, focusing on issues policy issues, community rela- More than 60 percent of the stu- Living Learning Center opened Emeritus Trustee Robert L. Virgil, germane to both college and tions, complaint resolution and dents come from more than 500 during the summer and may Ph.D., retired partner at Edward high-school education. High- special projects. miles away, and the class was qualify as one of the first green Jones and emeritus dean of the tech cheating, international The Center for Academic evenly divided between men and buildings to receive a Living Olin Business School. perspectives on academic integ- Integrity is a consortium of women. Building Challenge designation Also reviewed was the an- rity and classroom best practices more than 360 institutions Wrighton's report noted sig- from the Cascadia Region Green nouncement to the WUSTL com- will be among the topics covered. worldwide. It is affiliated with nificant construction achieve- Building Council. munity in September that a short- The conference is open to the the Robert J. Rutland Institute ments, including the BJC Institute The Chancellor noted that fall of $30 million was expected in public, but registration is re- for Ethics at Clemson of Health at Washington Uni- Stephen F. & Camilla T. Brauer fiscal year 2011 due to income quired. Fees for the program, University. versity, which is targeted for com- Hall for Engineering will be com- reductions derived from the loss which include meals and refresh- For more information on pletion in December. The struc- pleted in late spring 2010, ahead of endowment value, which stood ments, range from $225 for conference fees and a detailed ture will be the largest building in of schedule. Designed for LEED at $4.2 billion as of June 30, 2009. students from member institu- schedule, visit academicinteg- the University's history, and it is Gold certification, the new head- Central administrative units tions to $465 for nonmember rity.org or contact Dirk Killen, expected to receive LEED certifi- quarters for the School of Engi- and the six schools on the faculty, staff and administrators. associate dean in the College of cation from the U.S. Green neering will include facilities for Danforth Campus all will be Among those to be honored Arts & Sciences and the col- Building Council (USGBC) when the Department of Energy, Envi- affected and will begin the process is the late Sara L. Johnson, J.D., lege's academic integrity officer, it is completed. ronmental & Chemical Engineer- of resetting spending at a lower associate dean and academic at 935-9457 or dkillen@wustl. On the Danforth Campus, two ing and the Department of Bio- level. coordinator in the College of edu. —Gerry Everding new houses — South 40 and medical Engineering. "Washington University has Umrath — opened to students in The building will provide more underlying financial strength, August with a convenience store, than 150,000 square feet of learn- along with talented, creative and food services, fitness center and ing and research space, including dedicated faculty, students and the Bear Necessities shop operated more than 30 laboratories and a staff," Wrighton told the trustees. by the Women's Society. The sec- distance-learning classroom in- "We have exciting aspirations for ond phase of construction will be tended to extend the engineering the future, and I remain confident completed in August 2010 and school's reach around the world. about the continuing progress of Founded in 1905 • Washington University in St. Louis community news will include a dining area and Wrighton also outlined the the University as we strive to strengthen our quality and Volume 34, Number 9 impact." Lounge. Volunteers are always The trustees passed memorial Associate Vice Chancellor Steven J. Givens Record (USPS 600-430; ISSN 1043-0520), welcome and needed to help wrap resolutions for two recently de- Executive Editor Susan Killenberg McGinn Published for the faculty, staff and friends Give Back gifts. ceased board members — Mar- Editor Leslie Gibson McCarthy of Washington University. Produced weekly Associate Editor Neil Schoenherr garet Busch Wilson and I.E. Mil- during the school year, except school from Page 1 The program has a history of Assistant Editor Jessica Daues holidays, and monthly during June, July success at the University. The lstone. A longtime trustee and Medical News Editor Beth Miller and August by the Office of Public Affairs, Office of Student Activities be- national leader of the NAACP, Calendar Coordinator Angela Hall Washington University, Campus Box 1070, inspired by the generosity that the came involved in 1998 when staff Wilson was senior partner of Print Production Carl Jacobs One Brookings Drive, St. Louis, M0 63130. University shows every year" members adopted a single family. Wilson & Associates at the time of Online Production Tammy Ritterskamp Periodicals postage paid at St. Louis, M0. News & Comments Wilkie said. By 2001, the effort had evolved her passing. Millstone was presi- Where to send address changes University groups or individu- into a campus-wide program dent of K & M Investors as well as (314) 935-5293 Postmaster and nonemployees: Record, als can begin adopting families called Give Thanks Give Back. a major University benefactor and Campus Box 1070 Washington University, Campus Box 1070, following the kick-off party. Gifts In 2002, the University com- construction industry leader for [email protected] One Brookings Drive, St. Louis, MO 63130. are due by Nov. 13, and soon after munity adopted 83 families. In the region. Medical News Employees: Office of Human Resources, gift-wrapping parties are sched- each of the past six years, Give The trustees received reports (314)286-0119 Washington University, Campus Box 1184, from the following standing com- Campus Box 8508 One Brookings Drive, St. Louis, M0 63130. uled to prepare the donations for Thanks Give Back has adopted [email protected] individual recipients. more than 100 families. mittees: educational policy, audit, Reprint permission development, undergraduate Calendar Submissions Articles may be reprinted with permission This year, gift-wrapping events For more information or to Fax:(314)935-4259 are scheduled from noon-5 p.m. volunteer to help, e-mail gtgb@ experience, University finance, and with appropriate credit to Washington Campus Box 1070 University in St. Louis Record. on two consecutive Saturdays, sugroups.wustl.edu or visit medical finance and the alumni [email protected] Nov. 14 and Nov. 21, in Umrath sugroups.wustl.edu/~gtgb. board of governors. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 8,2009 3 School of Medicine Update Four of 106 heart replacement valves from pig hearts failed

BY GWEN ERICSON the valve manufacturer examined the failed pig heart valves, and no Pig heart valves used to re- specific cause for the valve failure place defective aortic valves was identified. The cause of early in human patients failed valve failure, whether it is related to much earlier and more often than patient factors or valve factors, expected, according to a report remains unclear, researchers said. from School of Medicine cardiac Estimates are that one in eight surgeons. people age 75 or older in the This is the first report to dem- United States have at least moder- onstrate this potential problem, ate heart valve disease, and more researchers said. than 100,000 heart valve proce- Between 2001-05, four of 106 dures are performed each year. patients with the pig valves im- These include procedures to either planted in the aortic position repair defective heart valves or developed severe impairment replace them with mechanical after less than four years, and the valves or with tissue replacement patients required surgery to re- valves — usually pig heart valves or place the valves. The findings valves formed from the pericardial were published in the Journal of sac of cow hearts. Generally, me- Thoracic and Cardiovas- chanical valves tend to last cular Surgery. longer than tissue valves, Exploring diversity Jeanne Shen, a fourth-year medical student, studies the photographs in Lead author Jennifer but patients who receive the "My Right Self: Transgender Considerations" exhibit at the Farrell Learning and Teaching S. Lawton, M.D., asso- them have an increased Center at the School of Medicine.The exhibit is a collection of 25 portraits of transgender people ciate professor of sur- risk of blood clots and with editorial captions on their experiences facing discrimination and in navigating health care. gery, said that the must take anticoagulants. The photographs are the work of Arthur Robinson Williams, a documentary photographer and a student at the University of Pennsylvania School of Medicine. The exhibit, sponsored by the valves are expected to "After valve replace- School of Medicine's LGBT Interest Group, will remain on display until Friday, Oct. 9. last 10-15 years in ment surgery, patients patients over 70. All typically get an echocar- four patients who need- diogram to check valve ed a "redo" operation structure at three, six were over 70. Lawton and 12 months and Children's Discovery Institute announces "We noticed an then yearly after that," increased incidence of this com- Lawton said. plication," Lawton said. "We were "If symptoms such as shortness four new pediatric research awards very concerned, and we believe it of breath, chest pain or lighthead- trained personnel will be available Center research effort. is important for others to know edness occur, more frequent exams Bringing new technologies to pediatric medical research is for use by all CDI researchers. This noninvasive technology is about it. A 4 percent failure rate maybe conducted. If patients have the focus of four new awards • Jeff Leonard, M.D., associate capable of accurately representing may not sound like a lot, but we had a pig valve implanted, I would professor of pediatrics and of electrical potentials and activation would not expect that many of the tell them that most likely they will granted to researchers at neurosurgery, remains the pri- patterns from the surface of the valves to fail in such a short pe- be fine, but if they have symptoms, Washington University by the Children's Discovery Institute mary investigator for the CDI heart. Investigators from pediatric riod of time." they need to see their cardiologist (CDI). Pediatric Brain Tumor Bank, cardiology, biomedical engineer- In the four patients affected, and get an echocardiogram." The awards, which began which has been awarded $700,000 ing and pediatric cardiac surgery the pig valves failed after three, Lawton first realized there July 1, total nearly $2.5 million in new funding. Joshua Rubin, will use the technology in their 14, 19 and 44 months. Each pa- might be a problem when one of and will enhance research efforts M.D., Ph.D., assistant professor of research efforts aimed at improv- tient underwent a second opera- her patients developed symptoms pediatrics, of neurology and of ing outcomes for patients with tion to replace the defective valve of valve impairment and needed a in all centers within the institute. neurobiology, continues as co- congenital heart disease. with a valve made from cow heart new valve after about a year. That • Todd Druley, M.D., Ph.D., investigator on the project. With . David Ornitz, M.D., Ph.D., tissue. No patient died as a direct prompted her to examine the re- instructor of pediatrics, will serve pediatric brain tumors, the ex- the Alumni Endowed Professor of consequence of the pig heart valve cords to see if other such cases had as the primary investigator for a project titled "Accelerating Novel treme difficulty in obtaining and Developmental Biology, has re- impairment. occurred. culturing brain tumor cells has ceived an award of $450,000 to The pig heart valves that failed Lawton said surgeons at Barnes- Genetic Discoveries via Next- Generation DNA Sequencing." severely hampered research. The support CDI investigations that early were Medtronic Mosaic Jewish Hospital and Washington New, next-generation sequencing brain tumor bank aims to over- use mouse models to study the porcine valves produced by University are no longer implant- technology has led to more than a come that limitation. genetic cause of disease. The grant Medtronic Inc. but were not from ing this valve and are waiting for To date, the tumor bank has will support a newly developed the same production lot. further data. She said there are 100-fold decrease in the cost of DNA sequencing. With co-inves- collected about 100 brain tumor cryopreservation protocol for Pathologists at WUSTL and at alternatives available for patients. tigator Robi Mitra, Ph.D., assistant specimens, from which genetically managing the mouse lines used in professor of genetics, Druley has faithful tissue culture and graft research, which are expensive to developed pooled sample se- models have been created. The develop and maintain. Division of Hospitalist Medicine quencing techniques, which fur- award will enable expansion of The technique, which uses ther accelerate the value of next- tumor types and characterization cryopreservation of sperm and marks 10th year at medical school generation DNA sequencing to of models to ensure they faithfully proprietary sperm injection tech- detect and quantify rare mirror the original disease. niques, can reduce risks to mouse BY DIANE DUKE WILLIAMS director of the BJC hospitalist mutations. • George Van Hare, M.D., the lines from natural disaster, infer- service. "It also has been well This unique equipment, along Louis Larrick Ward Chair in tility, genetic contamination, The Department of Medicine's received by physicians in the with the new methods Druley and Pediatric Cardiology at St. Louis disease outbreaks and spontane- Division of Hospitalist community." Mitra developed, will enable Children's Hospital and director of ous mutations. Medicine, which has grown from Donald Skor, M.D., a local investigators to rapidly and inex- pediatric cardiology at the School With the addition of these four five physicians to a staff of 47, is endocrinologist who uses the pensively tease apart the genetic of Medicine, has received a awards, CDI has made grants of celebrating its 10th year this fall. hospitalist service at Barnes- underpinnings of complex pediat- $200,000 award to bring a novel more than $6.5 million in 2009. Hospitalists are physicians who Jewish Hospital, is pleased with ric diseases. The $1,125 million electrocardiographic imaging Visit childrensdiscovery.org specialize in the care of patients in the results. award ensures that equipment and modality to the CDI's Heart for more information. the hospital. They usually have "I think we're fortunate that trained in internal medicine, the hospitalist program at family practice or Washington University pediatrics. Medical Center is very Carlson heads new hospitalist medicine division in pediatrics Most often, hospital- good," Skor said. "This is BY BETH MILLER include inpatient care for pediatric patients at ists treat patients re- a well-trained group, and St. Louis Children's Hospital, Missouri Baptist ferred by their primary- they communicate well The Department of Pediatrics has created a Medical Center and Progress West Healthcare care physicians. This with me." Division of Hospitalist Medicine, naming Douglas Center. step allows primary- The hospitalist trend, Carlson, M.D., as its director. In addition, the division is responsible for the care doctors to leave which has grown rapidly Although hospitalist medicine has been a section emergency departments at Missouri Baptist and their hospitalized pa- in the United States in of the pediatrics department for more than Progress West and the newborn nurseries at tients in the care of the past 10 years, has its 15 years, the division was formally created Missouri Baptist, Progress West and Barnes- physicians at the hospi- Thoelke roots in the United in September. Jewish Hospital. The program also oversees tal who can be reached Kingdom and Canada. Carlson, professor of pediatrics, will the sedation service, urgent care within the 24 hours a day. Thoelke said the demand oversee 37 faculty in the division, said Alan St. Louis Children's Hospital Emergency Hospitalists also monitor pa- for hospitalists has increased as L. Schwartz, Ph.D., M.D., the Harriet B. Room (C.A.R.E.S.) and the transport team tients who don't have primary-care community physicians become Spoehrer Professor and head of Pediatrics at St. Louis Children's Hospital. doctors, act as attending physi- more focused on outpatient clin- at the School of Medicine. Hospitalists also help referring physi- cians on the oncology service and ics. As a result, commuting to and "Doug is a superior clinician and educa- cians with the admissions process at provide a hospital-wide consult from the hospital has become less tor," Schwartz said. "He also is an accom- St. Louis Children's Hospital. service to fellow physicians. cost- and time-efficient. plished administrator who is nationally Carlson joined the School of Medicine "This model provides excellent "This is the fastest growing recognized for his leadership of our Carlson faculty in 1987 after completing an intern- care for patients, as we're around specialty in internal medicine, and program." ship and residency at St. Louis Children's throughout the day to provide I feel fortunate to be a part of this The pediatrics hospitalist medicine division Hospital. He also is director of Children's C.A.R.E.S. patient care and to provide up- growth," Thoelke said. "I strongly has grown significantly since it was established by at St. Louis Children's Hospital, director of pediatric dates to the families," said Mark believe this service provides add- F. Sessions Cole, M.D., vice chair of the Department emergency medicine at Missouri Baptist Medical S. Thoelke, M.D., associate profes- ed value to patients and their of Pediatrics, to provide clinical care and medical Center and co-coursemaster of pediatric medical sor of medicine and clinical families." student and resident education. Its services now student education at the School of Medicine. 4 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS University Events Shimomura opens his 'American Diary' for Sam Fox lecture series

Celebrated artist Roger nian Museum of American His- Shimomura, whose paintings tory in Washington, D.C. His and performances wittily experimental theater pieces have explore issues of culture, discrimi- been presented at such venues as nation and ethnic stereotypes, will the Franklin Furnace in New York discuss his work for the Sam Fox and the Walker Art Center in School of Design & Visual Arts' . fall Public Lecture Series at 6 p.m. A recipient of the Kansas Monday, Oct. 12. Governor's Arts Award, Shimo- The talk, titled "An American mura's many honors include more Diary," is free and open to the than 30 grants, including four public and takes place in Steinberg from the National Endowment for Hall Auditorium. the Arts. In 1994, he became the Shimomura was born in Seattle first fine arts faculty member in in 1939 but at age 3 was sent to University of Kansas' history to be Idaho's Minidoka War Relocation honored as a University Distin- Center, the camp for Japanese- guished Professor. Americans at which his family In 1998, he was the recipient was interned during World of the Higuchi Research Award, War II. the highest annual research hon- After their release, when or awarded to a faculty member Shimomura was 5, the family in humanities and social sciences. returned to Seattle and began His personal papers and letters are rebuilding their lives. He later being collected by the Smith- attended the University of sonian's Archives of American Washington, earning a bachelor's Art. degree in 1961. Shimomura's lecture is held in Shimomura joined the faculty conjunction with the semester- of the University of Kansas in Roger Shimomura's "Night Watch #3" from the series "Minidoka on my Mind" is an example of the flat, long series "Ethnic Profiling: A 1969, shortly after earning a mas- graphic approach combining American pop art with Japanese style ukiyo-e. Challenge to Democracy," orga- ter's degree from Syracuse nized by the Center for the Study University. Over the years, he has cartoons and Japanese ukiyo-e, or whose father disapproved of "ori- exaggerated ethnic costume as a of Ethics & Human Values. addressed sociopolitical issues "floating world," woodblock prints. entals" — depicts a yellow- young white man stares worriedly. For a complete schedule of affecting Asian-Americans Many of Shimomura's paintings skinned caricature snuggling up to Shimomura's work has been events or more information about through paintings and prints as draw on his own experiences and a pretty Roy Lichtenstein-like featured in more than 125 solo the series, call 935-9358 or visit well as theatrical performance on extensive diaries kept by his blonde. exhibitions and is included in the humanvalues.wustl.edu. pieces that combine the flat immigrant grandmother. One Another painting, based on a permanent collections of more For more information about graphic approach of American work, based on his memory of a profiling incident, depicts Shimo- than 80 museums, including the the Sam Fox School's Public pop art with imagery and motifs high-school dance in 1950s Seattle mura and Native American artist Whitney Museum of American Lecture Series, call 935-9300 or variously suggesting racist — which he attended with a girl Edgar Heap-of-Birds wearing Art in New York and the Smithso- visit samfoxschool.wustl.edu. Retinal Circuits • Medical Apartheid • Essays and Wikipedia

"University Events" lists a portion of the computer science, U. of III. at Urbana- to Your Little Friends: How Gut Bacteria 4 p.m. Vision Science Seminar Series. activities taking place Oct. 8-21 at Champaign. McDonnell Medical Sciences How to submit Shape Intestinal Immune Health." Sarkis "Hidden in Plain Sight: Mechanisms of Washington University. Visit the Web for Bldg., Rm. 823. 362-2139. Mazmanian, asst. prof, of biology, Calif. Immune Evasion by Ocular Tumors." Kyle expanded calendars for the Danforth C. McKenna, asst. prof, of ophthalmology 3 p.m. Siteman Cancer Center Basic Science 'University Events' Inst. of Technology. Cori Aud., 4565 Campus (news-info, wustl.edu/calendars) and immunology, l). of Pittsburgh School Seminar Series. Luis F. Parada, chair in McKinley Ave. 286-2890. and the School of Medicine (medschool. of Medicine. Maternity Bldg., Rm. 725. developmental biology, U. of wustl.edu/calendars.html). 12:15 p.m. Clinical Research Training 362-3315. Southwestern Medical Center. Eric P. Submit "University Events" Center Research Ethics Workshop. (Lunch Newman Education Center, Seminar B. items to Angela Hall of the served.) Co-sponsored by the Program for 4:15 p.m. Earth & Planetary Sciences 454-7029. the Ethical and Responsible Conduct of Colloquium. "Transient Rheology: Lab Record staff via: Experiments, Material Theory and the 4 p.m. Office of Technology Management Science and Scholarship. Farreli Learning Challenges of Spatiotemporal Scaling." Technology Commercialization Seminar e-mail — recordcalendar and Teaching Center, Connor Aud. Reid Cooper, prof, of geological sciences, Exhibits Series. "Obtaining Sponsored Research and Registration required: [email protected]. ©wustl.edu Brown U. Earth & Planetary Sciences Building Industry Relationships." Farreli wustl.edu. campus mail — Bldg., Rm. 203. 935-5610. "Chance Aesthetics." Through Jan. 4. Learning and Teaching Center, Connor Aud. 5 p.m. Freedom From Smoking Class. Campus Box 1070 Kemper Art Museum. 935-4523. 747-0908. "Stress Management and Weight Control." fax — 935-4259 "Metabolic City." Through Jan. 4. Kemper 4 p.m. Vision Science Seminar Series. Center for Advanced Medicine, Barnard Friday, Oct. 16 Art Museum. 935-4523. "Activity and the Organization of Retinal Upon request, forms for Health and Cancer Info. Center. To register: 9:15 a.m. Pediatric Grand Rounds. submitting events will be e-mailed, 362-7844. "My Right Self: Transgender Circuits." Daniel Kerschensteiner, asst. prof, "Pediatric AIDS: Worlds Apart." Mark Considerations." Through Oct. 9. Farreli of ophthalmology and visual sciences. mailed or faxed to departments to be 5:30 p.m. Academic Integrity Week Panel Kline, prof, of pediatrics, Baylor College of Learning & Teaching Center Atrium. Maternity Bldg., Rm. 725. 362-3315. filled out and returned. Discussion. "What do iPods, Essays and Medicine. Clopton Aud., 4950 Children's Place. 454-6006. [email protected]. 4:15 p.m. Earth & Planetary Sciences Deadline for submissions Wikipedia Have in Common? Intellectual Property From the Dorm to the Globe." Colloquium. "Effects of Hydration on the is noon the Thursday prior to 6 p.m. Center for the Study of Ethics & Danforth University Center, Rm. 276. Human Values Lecture. "The Children Left Elastic Properties of Mantle Materials and publication date. Earth's Deep Water Cycle." Steven D. 817-980-3130. Behind." Aram A. Schvey, staff attorney & Jacobsen, asst. prof, of earth & planetary 5:30 p.m. Biochemistry & Molecular teaching fellow, Georgetown U. Includes a Film sciences, Northwestern U. Earth & Planetary Biophysics Biophysical Evenings Seminar. slide presentation. Part of "Ethnic Profiling: Sciences Bldg., Rm. 203.935-5610. "Putting Nanomaterials to Work for A Challenge to Democracy" series. Umrath Biomedical Research." Younan Xia, prof, of Hall Lounge. For information: 5 p.m. Freedom From Smoking Class. CME Course. "Annual Update in humanvalues.wustl.edu. Thursday, Oct. 8 "Recovery and Support." Center for Cardiovascular Diseases." Cost varies. The biomedical engineering. Cori Aud., 4565 McKinley Ave. 362-4152. 7 p.m. Korean Film Series. "The Good, the Advanced Medicine, Barnard Health and Chase Park Plaza, 212 N. Kingshighway Bad, the Weird." Kim Ji-woon, dir. Seigle Cancer Info. Center. To register: 362-7844. Blvd. To register: 362-6891. Saturday, Oct. 17 Halt. Rm. L004. 935-5110. 7 p.m. Center for the Study of Ethics & 7:30 a.m.-5 p.m. Neurology, Neurosurgery Wednesday, Oct. 14 10 a.m. Physics Saturday Science Lecture Human Values Panel Discussion. "Security and Radiology CME Course. "Brain Attack! 3:30 p.m. History Colloquium. "Arab Series. "Production of the Elements: Monday, Oct. 12 Based Ethnic Profiling." Part of "Ethnic 2009: Networks and New Therapies." Cost: Perceptions of the Ottomans in the Early Evidence From Fossils Older than the Solar Profiling: A Challenge to Democracy" series. System." Ernst Zinner, research prof, of 7 p.m. Asian and Near Eastern Languages $185 for physicians, $145 for allied health Modern Period: Oppression, Acquiescence, Co-sponsored by the School of Law. Umrath professionals. Eric P. Newman Education physics. Crow Hall, Rm. 201.935-6276. and Literatures Middle East-North Africa or Enthusiasm?" Bruce Masters, prof, of Hall Lounge, humanvalues.wustl.edu. Film Series. "The Sparrow." (Discussion Center. To register: 362-6891. history, Wesleyan U. (Reception follows.) to follow.) Seigle Hall, Rm. L006. Co-sponsored by Jewish, Islamic and Near Monday, Oct. 19 935-5110. Eastern Studies. Busch Hall, Rm. 18. Friday, Oct. 9 Monday, Oct. 12 935-5450. Noon. Work, Families and Public Policy 9:15 a.m. Pediatric Grand Rounds. Annual 4 p.m. Immunology Research Seminar Brown Bag Seminar Series. "Neighbors Thursday, Oct. 15 Philip R. Dodge Lecture. "Contributions of Series. "Actin Assembly and Signaling at 6:30 p.m. Sam Fox School Public Lecture and Co-Workers: The Importance of Neurologists to Autism." Isabelle Rapin, Series. Adam Yarinsky, co-founder, Residential Labor Market Networks." David 7 p.m. Japanese Film Series. "Black Rain." Membranes: Mechanism and Regulation." prof, of neurology & pediatrics, Albert John Cooper, prof, of cell biology & Architecture Research Office. Steinberg Hall Neumark, prof, of economics, U. of Calif., McMillan Hall, Rm. 149. 935-5110. Einstein College of Medicine. Clopton Aud., physiology. Farreli Learning & Teaching Aud.935-9300. Irvine. Seigle Hall, Rm. 348. 935-4918. 4950 Children's Place. 454-6006. Center, Connor Aud. 362-2763. 7 p.m. Academic Integrity Week Panel 4 p.m. Immunology Research Seminar Friday, Oct. 16 11 a.m. Energy, Environmental & Chemical 4 p.m. Interdisciplinary Project in the Discussion. "Integrity Matters More than Series. "The Antibody Paradox." Jeffrey 7 p.m. St. Louis Film Conference. Film Engineering Seminar Series. "Aggregation Humanities Translation Lecture Series. Perfection: The Truth About Applying for Ravetch, prof, molecular genetics and Instructors' Showcase and Reception. and Bacterial Cytotoxity of Carbon-Based "Language Games: Conversations on Jobs & Grad School." Umrath Hall Lounge. immunology, The Rockefeller U. Farreli Shorts or scenes from the work of local Nanomaterials in Aquatic Environments." Translation. Let's Say Yes: Creating a New 817-980-3130. Learning & Teaching Center, Connor Aud. film educators. Steinberg Hall Aud. Menachem Elimelech, prof, of environmental Version of Dante's Inferno." Mary Jo Bang, 7 p.m. Kemper Art Museum Gallery Talk. 362-2763. Reservations required: and chemical engineering, Yale U. Lopata prof, of English. Duncker Hall, Rm. 101. "Playing With Chance: Duchamp, Chess 4 p.m. Siteman Cancer Center Breast [email protected]. Hall, Rm. 101.935-5548. 935-4200. and Roulette." Bradley Bailey, asst. prof, of Cancer Research Group Seminar Series. 4 p.m. Assembly Series. Jason Green, deputy 6:30 p.m. Center for the Study of Ethics & art history, Saint Louis U. (6 p.m. reception "Flies and Breast Cancer: A Search for Wednesday, Oct. 21 associate general counsel to President Human Values Lecture. "An American & games, 6:30 p.m. chess match.) Kemper Therapeutics." Ross L. Cagan, prof, of Art Museum. 935-4523. 7 p.m. Japanese Film Series. "Family Barack Obama. Wilson Hall, Rm. 214. Diary." Roger Shimomura, artist. Part of developmental & regenerative biology, Game." McMillan Hall, Rm. 149. 935-5110. 935-4620. "Ethnic Profiling: A Challenge to Mount Sinai School of Medicine. Farreli Democracy" series. Co-sponsored by the Learning & Teaching Center, Holden Aud. 7 p.m. Diversity Programs Lecture. Annual Thursday, Oct. 15 Sam Fox School of Design & Visual Art. 454-8981. Homer G. Phillips Public Health Lecture 11 a.m. Assembly Series. Center for Steinberg Aud. humanvalues.wustl.edu. Series. Harriet Washington, author of Academic Integrity Conference. David 5:30 p.m. Cardiac Bioelectricity & "Medical Apartheid: The Dark History of 7:30 p.m. Academic Integrity Week Panel Callahan, author. Graham Chapel. Arrhythmia Center Seminar. Medical Experimentation With African Discussion. "Could My Wash. U Degree 935-5285. "Arrhythmogenic Mechanisms in Inherited Lectures Americans From the Colonial Era to the Lose its Credibility?" Danforth University Catecholaminergic Polymorphic Ventricular Noon. Genetics Seminar. "Chemical and Present." (6 p.m. dinner, 8 p.m. panel Center, Rm. 276. 817-980-3130. Tachycardia." Jose Jalife, prof, of Thursday, Oct. 8 discussion.) Eric P. Newman Education Genetic Control of Melanocytes and cardiovascular research, U. of Mich. Center. To R.S.V.P.: 362-6854. Melanoma in Zebrafish." Elizabeth Patton, Medical School. (5 p.m. reception.) Noon. Genetics Seminar. "Function and Tuesday, Oct. 13 Edinburgh Cancer Research Centre, Whitaker Hall, Rm. 218. 935-7887. Evolution of Enhances in Drosophila Noon. Molecular Microbiology and Microbial Scotland. McDonnell Medical Sciences Development — The Informatics Saturday, Oct. 10 Pathogenesis Seminar Series. "Say Hello Bldg., Rm. 823.362-2139. Approach." Saurabh Sinha, asst. prof of 7:30 a.m.-7 p.m. Cardiovascular Disease record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 8,2009 5

Kennedy to present faculty recital Oct. 10 Pianist Martin Kennedy, Ph.D., Soprano Stella Markou, direc- trombonist for the SLSO. Sports assistant professor of compo- tor of Vocal Studies at the Next up will be "Suite," featur- sition and theory in the De- University ing violinists Dana Myers and partment of Music in Arts & of Missouri- Charlene Clark, both teachers of O'Brien leads 23-0 WUSTL improves to 11-7-6 Sciences, will present a free fac- St. Louis, and applied music; Weijing Wang, all-time against Emory and ended ulty recital at 2 p.m. Saturday, guitarist Vince violist for the SLSO; and violon- rout of Rhodes a five-game losing streak to the Varvel, teacher Oct. 10, in the 560 Music cellist Catherine Lehr, assistant Junior Jim O'Brien rushed for a Eagles. The Bears (6-1-3, 1-0 Center's E. Desmond Lee of applied principal cello for the SLSO career-high 146 yards and UAA) host No. 10 Carnegie Concert Hall. music, will After a brief intermission, the eclipsed 1,000 yards for his career Mellon University at 11 a.m. then perform The program will include five recital will conclude with "Piano to lead the football team to a 23-0 Sunday, Oct. 11, at Francis Field. Kennedy's "My original works by Kennedy, Concerto," featuring Kennedy as victory over Rhodes College Beloved is beginning with the recent well as pianist Peter Henderson, Oct. 3. Mine," fol- Cross country "Trivial Pursuits," performed by assistant professor of music at The Bears had a 378-273 ad- Kennedy lowed by Kennedy and violinist Erin Maryville University. vantage in total offense, including competes at classic Schreiber, assistant concertmas- "Theme and For more information, call a season-high 222 yards on the The men's and women's cross Variations," featuring Kennedy ter of the Saint Louis Symphony 935-5566 or e-mail kschultz@ ground. Junior quarterback country teams competed at the Orchestra (SLSO). and Timothy Myers, principal artsci.wustl.edu. Stephen Sherman was 11-for-17 Greater Louisville Classic Oct. 3, for 113 yards and touchdown, with the women taking ninth in a while sophomore wide receiver field of 35 teams and the men Easton Knott had two receptions finishing 17th in a field of 38. Chess meets 'Chance' at WUSTL Oct. 14 for 55 yards and a touchdown. The competitive meet featured mostly NCAA Division I schools. talk about Duchamps work by chess and gambling could meet in WUSTL evened its record at Iarcel Duchamp was 2-2 and returns to action Satur- Junior Taryn Surtees led the wom- Bradley Bailey, Ph.D., assistant the middle." among the most influen- day, Oct. 10, at No. 12-ranked en's squad, finishing 21st with a tial artists of the 20th professor of art history at Saint The 2009 U.S. Women's Chess Wabash College in Crawfords- time of 18:04.28 in the 5k run. For century. Louis University. Championship, which began ville, Ind. the men, junior Michael Burnstein He also was a dedicated chess Bailey recently co-authored Oct. 3 at the Chess Club and paced the team with a 45th-place player who saw strong correla- — with Jennifer Shahade, the 2002 Scholastic Center of Saint Louis, Women's golf finish and a time of 25:06.99 on tions between his art and the and 2004 U.S. Women's Chess 4657 Maryland Ave., includes the men's 8k course. game, famously remarking to the Champion, and independent 10 of the nation's elite players. ranked No. 9 in poll Both teams return to action scholar Francis Naumann, Ph.D. The final round of play will New York State Chess Associ- The women's golf team is ranked Saturday, Oct. 10, at the Cross — "Marcel Duchamp: The Art of take place Oct. 13, with the win- ation, "I have come to the per- No. 9 in the Golf World/National Country Challenge in Terre Chess," the first English-language ner crowned that evening. For sonal conclusion that while all Golf Coaches Association Div- Haute, Ind. study exploring the links between more information visit artists are not chess players, all ision III Coaches' Poll. Duchamps art and chess activities. saindouischessclub.org. chess players are artists." This marks the first time in Bailey also curated the exhibi- "Chance Aesthetics," on view Women's tennis At 6 p.m. Wednesday, Oct. 14, school history the Bears have tion "Marcel Duchamp: Chess at the Kemper Art Museum strong at regionals the Mildred Lane Kemper Art achieved a top 25 ranking. Museum and the Chess Club and Master" on view last summer at though Jan. 4, 2010, features more The women's tennis team per- Scholastic Center of Saint Louis the Saint Louis University than 60 artworks by more than 40 Volleyball has winning formed well at the 2009 Inter- will present "Playing with Chance: Museum of Art. avant-garde artists — including collegiate Tennis Association Duchamp, Chess and Roulette." For the Oct. 14 match, the Duchamp — from Europe and the weekend in Rochester Central Region Singles and The event — held in conjunc- players will employ a specially United States. The No. 5 volleyball team won Doubles Championships, held tion with the exhibition "Chance designed roulette wheel to deter- Organized by Meredith the first University Athletic Asso- Oct. 2-5 in Greencastle, Ind. Aesthetics" — will begin with a mine their moves — thus combin- Malone, Ph.D., the museum's ciation (UAA) round robin of the WUSTL was led by freshman live game combining roulette and ing the ultimate game of strategy assistant curator, the exhibition season with a 3-0 record last Kate Klein, who posted a 4-1 chess played in the museum's with the ultimate game of chance. investigates the use of chance and weekend in Rochester, N.Y. record en route to a semifinal atrium by the newly crowned "The game features a merging randomness as key compositional The Bears defeated Brandeis appearance in the singles draw. 2009 U.S. Women's Chess of roulette and chess that I created principles in modern art. University, 3-0, Oct. 3 and then Senior Allison Dender and Champion (to be determined with curator Larry List," said Both the exhibition and the swept the University of Rochester sophomore Natalie Tingir ad- Tuesday, Oct. 13) as well as a Shahade, who will be in atten- Oct. 14 events are free and open and Case Western Reserve vanced to the semifinal round of special guest. dance. "The idea was inspired by to the public. For more informa- University Oct. 4. the main doubles draw. Dender Immediately following the roulette- and chess-crazed tion, call 935-4523 or visit Senior middle hitter Erin won the consolation singles brack- match at 7 p.m. will be a gallery Duchamps wish that somehow kemperartmuseum.wustl.edu. Albers had the best weekend et, and sophomore Luisa Errichetti offensively, leading the team with and senior Stacey Goebel played 33 kills, 3.67 per set, and a .407 into the semifinal round of the consolation doubles tournament. Tuesday, Oct. 20 Latin America's Great Myth of Origin." John Saturday, Oct. 10 hitting percentage. Freshman Chasteen., prof, of Latin American history, Marilee Fisher had 108 assists WUSTL has concluded play for Noon. Barnes-Jewish Hospital Ethics The U. of N.C. at Chapel Hill. Duncker Hall, 11 a.m. Volleyball vs. U. of Wis.-La Crosse. over three matches, and freshman the fall season and will be back in Committee Lunch and Learn Brown Bag Rm. 201, Hurst Lounge. 935-5175. Washington University Invitational. WU Field action in early 2010 for the spring Forum. "Health Care Reform: Are New House. 935-4705. libero Kelly Pang averaged 6.0 Ethical Issues Raised?" Andy Ziskind, senior digs per set, tallying 54 over the season. vice president, BJC Healthcare. Clopton Sunday, Oct. 11 weekend. Aud., 4950 Children's Place. 747-5361. WUSTL (15-3, 3-0 UAA) 11 a.m. Men's Soccer vs. Carnegie Mellon Women's soccer Noon. Molecular Microbiology and Microbial Music U. Francis Field. 935-4705. hosts the Washington University ties at Emory Pathogenesis Seminar Series. "Life or Invitational this weekend at the 1:30 p.m. Women's Soccer vs. Carnegie Death: Modulation of Cell Cycle and Cell WU Field House. The Bears begin The No. 13-ranked women's soccer Death by Human Cytomegalovirus." Dong Thursday, Oct. 8 Mellon U. Francis Field. 935-4705. play Friday, Oct. 9, facing team posted a 1-1 double overtime Yu, asst. prof, of molecular microbiology. 8 p.m. Jazz at Holmes. Miles Davis tribute Cori Aud., 4565 McKinley Ave. 286-1123. Elmhurst College at 5:15 p.m., tie at Emory University in the recreating "Birth of the Cool." Ridgley Hall, Tuesday, Oct. 13 University Athletic Association Holmes Lounge. 862-0274. and Central College at 7:30 p.m. 5 p.m. Freedom From Smoking Class. "Fun 7 p.m. Men's Soccer vs. Fontbonne U. (UAA) opener for both teams Exercise and Assertive Communication." Francis Field. 935-4705. Center for Advanced Medicine, Barnard Saturday, Oct. 10 Men's soccer tops Oct. 4 in Atlanta. Health and Cancer Info. Center. To register: Sophomore Emma Brown 362-7844. 2 p.m. Faculty Recital. Martin Kennedy. Friday, Oct. 16 Emory in UAA opener scored the lone goal for WUSTL at E. Desmond Lee Concert Hall, 560 Trinity 5:30 p.m. Men's Soccer vs. Case Western The men's soccer team is off to a the 21:32 mark in the first half. Ave. 935-5566. Reserve U. Francis Field. 935-4705. Wednesday, Oct. 21 1-0 start in University Athletic The goal was Brown's UAA- 8 a.m.-4 p.m. Infectious Diseases CME 8 p.m. Women's Soccer vs. Case Western Association (UAA) play, thanks to leading 10th of the season. Sunday, Oct. 11 Reserve U. Francis Field. 935-4705. Conference. "Annual Infectious Disease a 2-0 win at Emory University Freshman Clara Jaques played all Update for Primary Providers — New Faces 3 p.m. Concert. Symphony Orchestra. Oct. 4. 110 minutes in goal, facing 13 of Old Foes: C.difficile and Novel H1N1 E. Desmond Lee Concert Hall, 560 Trinity Saturday, Oct. 17 Influenza." Cost: $135 for physicians, $115 Ave. 935-5566. Junior Harry Beddo scored the shots and making a career-high for allied health professionals. Eric P. 1 p.m. Football vs. College of Wooster. game-winning goal in the 13th eight saves. Newman Education Center. 454-8275. Sunday, Oct. 18 Francis Field. 935-4705. minute to lift the Bears to the The Bears (7-2-1, 0-0-1 UAA) stepped out of conference play Noon. Siteman Cancer Center Prevention & 3 p.m. Concert. Liederabend, featuring win. Senior John Hengel added Control Seminar Series. "If We Want More Jennifer Jakob. Graham Chapel. 935-5566. Sunday, Oct. 18 an insurance score in the 81st Oct. 7 at Division II University Evidence-Based Practice, We Need More Noon. Men's Soccer vs. U. of Rochester. minute. Senior goalkeeper John of Missouri-St. Louis. WUSTL Practice-Based Evidence." Lawrence W. Francis Field. 935-4705. hosts UAA foe Carnegie Mellon Green, adjunct prof., U. of Calif., San Monday, Oct. 19 Smelcer made five saves, picking Francisco. Goldfarb Hall, Rm. 132. 2:30 p.m. Women's Soccer vs. U. of up his fifth shutout of the season University at 1:30 p.m. Sunday, 7 p.m. Center for the Study of Ethics & Rochester. Francis Field. 935-4705. 454-8981. Human Values Lecture Concert. Musicians and the 25th of his career. Oct. 11. 3:30 p.m. History Colloquium. "A History of from the St. Louis Symphony Orchestra will Qi in China and America." Ruth Rogaski, perform & original poems about ethnic assoc. prof, of Asian studies, Vanderbilt U. poetry will be read. (Snacks provided.) Part (Reception follows.) Co-sponsored East of "Ethnic Profiling: A Challenge to Asian studies. Busch Hall, Rm. 18. Democracy" series. Ridgley Hall, Holmes On Stage 935-5450. Lounge. For information: humanvalues. wustl.edu. 4 p.m. Biochemistry & Molecular Biophysics Friday, Oct. 16 Seminar. "Mitochondrial Biogenesis and 8 p.m. Performing Arts Dept. Presentation. Heredity." Daniel Bogenhagen, prof, of Wednesday, Oct. 21 "Ragtime." (Also 8 p.m. Oct. 17,23 and 24, pharmacological sciences, The State U. of 8 p.m. Concert. Danforth University Center 30 and 31; 2 p.m. Oct. 18.) Edison Theatre. New York. McDonnell Medical Sciences Chamber Music Series. "For the Love of the 935-5858. Bldg., Rm. 264. 362-4152. Cello." Danforth University Center, Formal 4:30 p.m. Romance Languages and Lounge. 935-5566. Literatures Lecture. "The Dance of Two and And More Green Your Office Sports Wednesday, Oct. 21 Shredding paper helps WUSTL's Friday, Oct. 9 6-9 p.m. Center for the Study of Ethics & recycling efforts. Through the Human Values Fashion Show. "The Way University's contractor, Shred-it, 5:15 p.m. Volleyball vs. Elmhurst College. People Dress: Clothing and Ethnic Profiling.' Washington University Invitational. WU Bonnie Kruger, senior lecturer in drama. WUSTL recycles more than Field House. 935-4705. Part of "Ethnic Profiling: A Challenge to 725,000 pounds of paper; this is 7:30 p.m. Volleyball vs. Central College. Democracy" series. (Panel discussion 125,000 pounds more than Washington University Invitational. WU follows.) Women's Bldg. humanvalues. WUSTL recycles through its Field House. 935-4705. wustl.edu. mixed-paper collection. Sophomore Emma Brown leads the UAA in goal-scoring. 6 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS

Retirees honored by WUSTL

BY JESSICA DAUES form of service to the commu- Noted arch itect Yarinsk y to speak nity," Glore said. "They have When Adrienne Glore, former embraced community service associate dean of students, within and beyond campus as a for Sam Fox School Oct. 14 arrived at Washington Univer- critical part of their own sity in the late 1970s, the Uni- development." Jft dam Yarinsky, a principal ARO's built projects have led by Peter Rose & Partners of versity was evolving from a Glore was one of 26 staff ■ M and co-founder of ARO: ranged from the U.S. Armed Boston and also included archi- small, streetcar college to an members who retired from the ^^Architecture Research Forces Recruiting Station in tecture alumnus Gullivar international, world-class University this past year. All 26 Office in New York, will dis- Times Square and the stunning Shepherd of Michael van university. retirees received a commenda- cuss his work for the Sam Fox Colorado House in Telluride to Valkenburgh Associates, land- Glore, who retired from the tion from Chancellor Mark School of Design & Visual Arts the restorations of the Donald scape architects. University this past year after 31 S. Wrighton and a walnut fall Public Lecture Series at Judd loft in 's The competition was orga- years of service, witnessed many plaque featuring the University 6:30 p.m. Wednesday, Oct. 14, SoHo neighborhood and the nized by Sitra, an independent changes as WUSTL has devel- seal and the number of years of in Steinberg Hall Auditorium. School of Architecture at public fund promoting the oped, but she said the way his or her service. Yarinsky is serving as a Princeton University. welfare of Finnish society, and WUSTL students have embraced "I am proud of the visiting professor in the Sam The firm's numerous awards aimed to show that interna- community service has im- Washington University com- Fox School's College of include two National Honor tional targets for lowering CO2 pressed her the most. munity and recognize that the Architecture and Graduate Awards from the American emissions can be reached and "When I first came here, tradition of excellence we enjoy School of Architecture & Institute of Architects (ALA); even outperformed while also students focused on their own is due in large measure to the Urban Design. He launched multiple Merit Awards from the maintaining high levels of eco- promise, their own personal support provided to our stu- ARO in 1993 with partner ALA New York Chapter; and a nomic and architectural value. success," Glore said. "While dents and faculty by our staff Stephen Cassell, and in the Design Distinction Award from The groups design — re- certainly that was important, members," Wrighton said. "Our years since, the firm has earned ID Magazine. Twice, ARO has cently named one of five final- there seemed to be something staff has been an integral part a reputation as equal parts been a finalist for the Smith- ists as the competition moves missing — something more was of the Washington University design office and research sonian Cooper-Hewitt Museum's from the ideas to implementa- needed to round out their success story, and I value your laboratory. National Design Award for tion stage — would create a experience. service and loyalty." In the mid-1990s, ARO Architecture. large yet energy-efficient build- "Toward the last half of my The 26 retirees contributed a began experimenting with In 2003, Princeton Architec- ing complex on a reclaimed career, the missing piece total of 546 years of service to standard-sized plywood to tural Press published a mono- harbor in the Jatkasaari quarter, emerged among students in the the University. create its flexible Modular Wall graph of their work. In 2007, located at the western edge of system, while the Paper Wall Yarinksy was made a fellow of Helsinki's central business project in 2000 employed the ALA. district. computer-aided manufacturing Last summer, ARO collabo- For more information about Retirees and their lengths of service technologies — which are rated with Peter MacKeith, asso- Low2No, visit low2no.org/ capable of cutting and scoring ciate dean and associate profes- competition/. Jane N. Bettlach (33 years); Rosemarie B. Brefeld (18 years); in ways that cannot be repli- sor of architecture, as part of the Yarinsky s talk is free and A. Van Brokaw (21 years); Edna Ruth Canada (28 years); Karen cated by hand — to create a Low2No Sustainable Develop- open to the public. For more Levin Coburn (28 years); Catherine E. Cummings (23 years); David dimensional wall structure ment Design Competition in information call 935-9300 or Anthony Fitzpatrick (22 years); Adrienne Lyman Glore (31 years); entirely out of paper. Helsinki, Finland. The team was visit samfoxschool.wustl.edu. Rosemary Hahn (38 years); John W. Hansford (25 years); Dorothy L. Kelly (23 years); Stephen F. Kuppinger (27 years); Mary Ann Layton (10 years); Frances E. Noonan (5 years); Sharon K. Panian (16 years); Mindy Price (19 years); Linda R. Ragsdale (12 years); Law school's empirical research center receives Louis P. Recht III (20 years); Mary E. Rydgig (15 years); Martha E. Simpson (17 years); Ralph H. Thaman Jr. (16 years); Patricia grant to help update Supreme Court Database M. Thomann (18 years); Bobby Lee Trulove (32 years); Ronald Nelson Van Fleet II (9 years); George Michael Veith (35 years); Researchers at the School of throughout the court's history. effort among scholars at North- Law's Center for Empirical "The Supreme Court Database western University, and Carol A. Wibbenmeyer (5 years). Research in the Law (CERL) will project is important to the aca- State University, the University of receive $191,000 to update the demic community and the pub- Pennsylvania, Princeton Univer- Supreme Court Database as part lic," said Andrew D. Martin, sity, Stony Brook University and of a $900,000 grant from the Ph.D., professor of law and pro- Washington University. element in rock," Fegley said, "so National Science Foundation. fessor and chair of the CERL serves as the techno- when you vaporize rock, what you The database, originally cre- Department of Political Science logical home for the project and Exoplanet end up doing is producing a lot of ated by Harold Spaeth, J.D., pro- in Arts & Sciences. "Hundreds of is responsible for maintaining Math calculations used oxygen." fessor of political science at academic studies are based on and updating the project's Web- to model atmosphere The peculiar atmosphere has Michigan State University, con- these data, and having a more based infrastructure. - from Page 1 its own singular weather. "As you tains information about all comprehensive collection will Martin, the founding director go higher, the atmosphere gets Supreme Court cases from 1953 to broaden the scholarly impact. of CERL, said that, when com- cooler and eventually you get the present. "The project also provides a plete, the database will "open up COROT-7b's atmosphere has ■ saturated with different types of Over the next four years, the Web tool that lawyers, journalists the doors to all types of questions none of the volatile elements or 'rock' the way you get saturated database will be expanded to and interested citizens can use to that we haven't been able to compounds that make up Earth's with water in the atmosphere of include cases dating back to the research cases and perform sta- answer before." atmosphere, such as water, nitro- Earth," Fegley said. first case heard by the Supreme tistical summaries of the He said that scientists and gen and carbon dioxide. "But instead of a water cloud Court in 1793. Supreme Court," Martin said. legal scholars for the first time "The only atmosphere this forming and then raining water Once complete, it will be the "The project will greatly contrib- will be able to map the nations object has is produced from vapor droplets, you get a 'rock cloud' most comprehensive repository of ute to our understanding of the legal development dating back to arising from hot molten silicates forming and it starts raining out statistical records available, span- court." the Supreme Court's first in a lava lake or lava ocean," little pebbles of different types of ning every justice vote and case The project is a collaborative decisions. Fegley said. rock," Fegley said. To find out what the atmo- Even more strangely, the kind sphere was like, Schaefer and of rock condensing out of the Fegley used thermochemical cloud depends on the altitude. we're awake." injected orexin into the brains of equilibrium calculations to model The atmosphere works the same Depriving the mice of sleep the mice, mice stayed awake COROT-7b's atmosphere. way as fractionating columns, the Sleep caused a 25 percent increase in longer and amyloid beta levels The calculations, which reveal tall knobby columns that make Brain's synapses more amyloid beta levels. Levels were increased. which mineral assemblages are petrochemical plants recognizable active when awake lower when mice were allowed to When researchers used a drug stable under different conditions, from afar. - from Page 1 sleep. Blocking a hormone previ- called almorexant to block both were carried out with MAGMA, In a fractionating column, ously linked to stress and amyloid orexin receptors, amyloid beta a computer program Fegley crude oil is boiled and its compo- beta production had no effect on levels were significantly lower and developed in 1986 with the late nents condense out on a series of fluid led by Randall Bateman, these changes, suggesting that animals were awake less. A.G.W. Cameron, Ph.D., a profes- trays, with the heaviest one (with M.D., assistant professor of they weren't caused by the stress Miranda M. Lim, M.D., Ph.D., sor of astrophysics at Harvard the highest boiling point) sulking neurology, also showed that of sleep deprivation, Holtzman a neurology resident and postdoc- University. at the bottom, and the lightest amyloid beta levels generally said. toral researcher in Holtzman's lab, Schaefer and Fegley modified (and most volatile) rising to the were higher when subjects were performed long-term behavioral the MAGMA program in 2004 in top. awake and lower when they experiments with the mice. order to study high-temperature Instead of condensing out slept. She found that three weeks of volcanism on Io, Jupiter's inner- hydrocarbons such as asphalt, To confirm the link, Kang "This suggests the chronic sleep deprivation acceler- most Galilean satellite. This modi- petroleum jelly, kerosene and learned to use electroencepha- ated amyloid plaque deposition in fied version was used in this work. gasoline, the exoplanet's atmo- lography (EEG) on the mice at possibility that a the brain. Because the scientists didn't sphere condenses out minerals the Sleep and Circadian Neuro- treatment like this In contrast, when mice were know the exact composition of such as enstatite, corundum, biology Laboratory at Stanford given almorexant for two months, the planet, they ran the program spinel, and wollastonite. In both University with researchers Seiji could be tested to see plaque deposition dropped by with four different starting com- cases, the fractions fall out in Nishino, M.D, Ph.D., and if it could delay the more than 80 percent in some positions. "We got essentially the order of boiling point. Nobuhiro Fujiki, M.D, Ph.D. brain regions. same result in all four cases," Elemental sodium and potas- The EEG readings let re- onset of Alzheimer's "This suggests the possibility Fegley said. "Sodium, potassium, sium, which have very low boiling searchers more definitively de- disease." that a treatment like this could be silicon monoxide and then oxy- points in comparison with rocks, termine when mice were asleep tested to see if it could delay the gen — either atomic or molecular do not rain out but would instead or awake and validated the con- DAVID M. HOLTZMAN onset of Alzheimer's disease," oxygen — make up most of the stay in the atmosphere, where nection: Mice that stayed awake Holtzman said. atmosphere." they would form high gas clouds longer had higher amyloid beta Holtzman said that not only But there are also smaller buffeted by the stellar wind from levels. does the risk of Alzheimer's in- amounts of the other elements COROT-7. "This makes sense in light of Researchers elsewhere had crease with age, the sleep/wake found in silicate rock, such as These large clouds may be an earlier study in our lab where linked mutations in orexin to cycle also starts to break down, magnesium, aluminum, calcium detectable by Earth-based tele- John Cirrito (Ph.D., research narcolepsy, a disorder character- with older adults progressively and iron. scopes. The sodium, for example, assistant professor of neurology) ized by excessive daytime sleepi- getting less sleep. Why is there oxygen on a dead should glow in the orange part of showed that increases in synaptic ness. The brain has two kinds of Investigators are considering planet — when it didn't show up the spectrum, like a giant but very activity resulted in increased receptors for orexin, which also is epidemiological studies of wheth- in Earth's atmosphere until 2.4 faint sodium vapor streetlamp. levels of amyloid beta," Holtzman associated with regulation of er chronic sleep loss in young and billion years ago — when plants Observers have recently spot- said. "The brain's synapses may feeding behavior. middle-aged adults increases risk started to produce it? ted sodium in the atmospheres of generally be more active when When Holtzman's group of Alzheimer's disease later in life. "Oxygen is the most abundant two other exoplanets as well. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 8,2009 7 Notables

Gehlert to be installed as E. Desmond Lee University Libraries receives grant Professor of Racial and Ethnic Diversity to digitalize historic court records

BY JESSICA MARTIN her ability to work across scientific Research, now a joint center with disciplines as well as work effec- WUSTL. 1 Afashington University The project will fund a Sarah Gehlert, Ph.D., will be tively with diverse communities to Gehlert's publications focus on ■ ■ Libraries has received a course through American installed as the E. Desmond address disparities," said Edward social influences on health, espe- $376,426 National Leadership culture studies to be taught by Lee Professor of Racial and F. Lawlor, Ph.D., dean and the cially the health of vulnerable Grant from the Institute of Kenneth Winn, Ph.D., former Ethnic Diversity at the George William E. Gordon Distinguished populations. She is working on the Museum and Library Services state archivist. Warren Brown School of Social Professor. "Her work embodies the influence of neighborhood and for "The St. Louis Freedom "The course will provide an Work at 4 p.m. Wednesday, spirit of community engagement community factors, such as com- Suits Legal Encoding Project" opportunity for students to Oct. 14, in the Brown Hall on which the E. Desmond Lee munity violence and unsafe hous- — one of the largest grants engage with primary source Lounge. chair is based." ing, on psychosocial functioning ever received by the University material in a new way — The professorship is named for Gehlert, also a scholar at the among African-American women . Libraries. through contributing to a Lee, former chairman of Lee/ Institute for Public Health, joined newly diagnosed with breast The University Libraries digital project in addition to Rowan Co., which Lee co-found- the Brown School in 2009 from the cancer. will partner with the Missouri traditional methods," said ed in 1939. A WUSTL alumnus, University of , where she Gehlert, president of the History Museum and several Andrew Rouner, Ph.D., digital Lee is known for his widespread was the Helen Ross Professor in Society for Social Work and internal partners — including library director. philanthropic efforts, encouraging the School of Social Service Ad- Research, serves on the external the Humanities Digital "Beyond creating a rich community and regional partner- ministration, Institute of Mind and advisory committee of the Univer- Workshop, the Law School resource for users," Rouner ships to better educate people of Biology, and the Department of sity of Chicago's Specialized Pro- Library and the American said, "one of the most exciting all ages and economic back- Comparative Human Develop- gram of Research Excellence in Culture Studies Program in aspects of the project is the grounds. ment. She is a research member of Breast Cancer and the Chicago Arts & Sciences — on the broad collaboration not only In 1996, Lee was named the Siteman Cancer Center. Breast Cancer Mortality Reduc- project, which focuses on outside but within the St. Louis Man of the Year, and While at Chicago, Gehlert tion Task Force. pre-CMl War suits brought by University, and the opportunity in 1997, he received the National served as the associate director of Her professional activities also enslaved persons against slave- for the library to engage as Outstanding Philanthropist the university's National Institutes include memberships on the holders in the St. Louis Circuit partners more directly with Award. In 1999, Worth magazine of Health (NIH)-funded Institute nine-member board of scientific Court. faculty and students in the named Lee one of "The 100 Most for Translational Medicine and councilors of the National Human In addition to transcribing academic enterprise." Generous Americans." co-chaired its Community Genome Research Institute at the records, the project will The two-year project begins For his outstanding efforts, the Translation Science Cluster. NIH; the professional advisory develop a standard for encod- Dec. 1. For more information, University bestowed Lee with the She remains the principal in- board of the Epilepsy Foundation ing the legal function of the e-mail Rouner at arouner@ Robert S. Brookings Award in vestigator and director of the of Greater Chicago; and the steer- documents, which will provide wustl.edu or visit digital.wusd. 2000 as well as an honorary de- University of Chicago's NIH- ing committee of the Washington a model for similar archives. edu. gree in 2002. funded Center for Inter- Park Children's Free Clinic in "Sarah is a unique scholar in disciplinary Health Disparities Chicago.

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Reinvestment Act.... high-school juniors and seniors to Institute of Child Health & grant was Andrew A. Nyblade, Francesc Ferrer, Ph.D., assis- the various aspects of the scientif- Human Development for research Ph.D., of Pennsylvania State Of note tant professor of physics in Arts 8c ic enterprise as practiced by scien- titled "Time Use and Household University. This grant is supported Sciences, has received a three-year, tists in academic, private or cor- Production." This grant is sup- by the American Recovery and Elizabeth Brunt, M.D., profes- $120,000 grant from the National porate research institutions. ... ported by the American Recovery Reinvestment Act. sor of pathology and immunology, Science Foundation for research Sophia E. Hayes, Ph.D., asso- and Reinvestment Act. ... has received a five-year, $329,257 titled "Research in Cosmic Rays, ciate professor of chemistry in Gang Shen, Ph.D. postdoc- subcontract from Saint Louis Magnetic Fields and the Nature of Arts & Sciences, has received a toral research associate in chemis- University and the National Dark Matter." ... three-year, $375,539 grant from try in Arts 8c Sciences, has re- Speaking of Institute of Diabetes and Digestive First-year students Nate Haus- the National Science Foundation ceived a three-year, $342,000 and Kidney Diseases for research fater, Jereme Kramer, Zach for research titled "MRI: De- grant from the United States Cynthia Hudson and Makiba titled "The Saint Louis University Levinson, Varun Manohara, velopment of Combined Op- Army Medical Research Acqui- Foster, WUSTL librarians, pre- Component of the NASH Clinical Andrew Wiens and Mark Wil- tically-pumped and Optically- sition Activity for research sented on "Social Media and Research Network." ... ensky are graduates of the 2008 detected NMR of Bulk and Nano- titled "Development of Lipid Collaboration 2.0" at the annual Sarah C.R. Elgin, Ph.D., the Students and Teachers as Research structured Semiconductors." This and Nanoparticle-Based Anti- Association of Specialized and Viktor Hamburger Professor in Scientist (STARS) Program, spon- grant is supported by the Ameri- sense Breast Cancer Imaging Professional Accreditors (ASPA) Arts & Sciences, has received a sored by the University of Mis- can Recovery and Reinvestment Agents." ... conference in St. Louis Sept. 13. two-year, $201,488 grant from the souri-St. Louis. For their work, Act.... Philip Skemer, Ph.D., assis- The ASPA is an association of National Institute of General Levinson and Weins received the Kenneth F. Kelton, Ph.D., the tant professor of earth and plan- U.S. agencies that assess the qual- Medical Sciences for research LMI Aerospace/D3 Technologies Arthur Holly Compton Professor etary sciences in Arts & Sciences, ity of specialized and professional titled "Formation, Structure and Award for Excellence in Research. in Arts & Sciences and chair of has received a four-year, $285,000 higher education programs and Function of Heterochromatin." Washington University faculty the Department of Physics, has grant from the National Science schools. Member organizations This grant is supported by the members serve as mentors to the received a three-year, $405,000 Foundation for research titled include the American Library American Recovery and STARS program, which introduces grant from the National Science "Deformation and Micro- Association, American Dental Foundation for research tided structural Evolution of Harz- Association and American "Relations Between Structure, burgite." This grant is supported Medical Association.... Phase Formation and Phase by the American Recovery and Alex MacCurdy, senior in the Transitions in Supercooled Reinvestment Act.... School of Engineering and Metallic Liquids and Glasses." ... William D. Smart, Ph.D., Campus Watch Applied Science, presented his Rebecca Lester, Ph.D., assis- assistant professor of computer research on "Vacuum Insulation tant professor, and Anubha Sood, science and engineering, has Systems in Cryogenic Storage graduate student, both in anthro- received a three-year, $487,209 Vessels" at the NASA Under- The following incidents were reported to University Police Sept. 30-0ct. 5. pology in Arts & Sciences, have grant from the National Science graduate Student Research Readers with information that could assist in investigating these incidents are received a one-year, $7,025 grant Foundation for research tided Program this past summer at urged to call 935-5555. This information is provided as a public service to from the National Science "HCC: Small: A Physical John C. Stennis Space Center in promote safety awareness and is available on the University Police Web site at Foundation for research tided Vocabulary for Human-Robot Mississippi. Working with NASA police.wustl.edu. . - "Women's Pathways to Mental Interaction." ... scientists and engineers, students Health: Comparing Psychiatry Radhakrishna Sureshkumar, participating in the program Sept. 30 4:27 p.m. — A student re- and Mystical-Spiritual Healing in Ph.D., professor of chemical conducted and presented research ported money had been taken Urban North India." ... engineering, has received a three- 10:46 a.m. — A student during the 10-week internship on from her backpack at Olin Mark J. Miller, Ph.D., year, $174,992 grant from the reported that an iPod and a select topic.... Library. assistant professor of pathology National Science Foundation for wallet were stolen from a Yoram Rudy, Ph.D., the Fred and immunology, has received a research titled "Towards a backpack at Olin Library. Oct. 3 Saigh Distinguished Professor of five-year, $1,900,000 grant from Molecular-Scale Understanding 1:14 p.m. — A backpack Engineering, delivered the Tawara 10:47 a.m. — A laptop was the Nat-ional Institute of Allergy of Flow-Induced Gelation in containing a laptop was re- Lecture "Cardiac Excitation and reported stolen from Olin and Infectious Diseases for re- Rodlike Micelle Solutions." ... ported stolen at Olin Library. Arrhythmia in the Human Heart: Library. search tided "Bacterial Capture Xiang Tang, Ph.D., assistant 2:04 p.m. — Two cars were Insights from Noninvasive ECG and Antigen Presentation in professor of mathematics in Arts broken into while parked Imaging (ECGI)" at the Inter- Oct. 4 Spleen." ... 8c Sciences, has received a three- outside Whitaker Hall. national Congress of Physio- 10:31 a.m. — A purse con- Juan B. Pena, Ph.D., assistant year, $109,088 grant from the 5:15 p.m. — A purse was logical Sciences in Kyoto, Japan, taining a camera was reported professor of social work, has National Science Foundation for reported stolen from an office July 30. During Aug. 2-13, Rudy stolen from South 40 House. received a two-year, $152,000 research titled "Noncommutative in Givens Hall. presented a series of invited lec- grant from the National Institute Geometry: Its Applications to tures in Taiwan at the following of Mental Health for research Geometry and Analysis." ... Oct. 1 Additionally, University police universities: National Taiwan titled "Suicidal Behaviors Among Douglas A. Wiens, Ph.D., 12:18 p.m. — A book bag responded to five sick cases, two University in , National Dominican Youth." ... professor of earth and planetary was reported stolen from Olin accidental injuries, one automo- Cheng Kung University in Tainan, Robert A. Pollak, Ph.D., the sciences in Arts 8c Sciences, has Library. bile accident, one lost item, one Providence University, and Na- Robert E. Hernreich Distin- received a three-year, $249,999 report of damaged property, one tional Chung Hsing Universities in guished Professor of Economics grant from the National Science Oct. 2 report of fraud, one report of Taichung. A National Workshop at in the Olin Business School and in Foundation for research titled 1:55 p.m. — A student tampering and one resisting National Cheng Kung University Arts & Sciences, has received a "Polenet East: An International reported a backpack was stolen arrest. Aug. 2 celebrated 18 years to the two-year, $335,516 grant from the Seismological Network for East from Olin Library. publication of the Luo-Rudy mod- Eunice Kennedy Shriver National Antarctica." Also receiving the el of the cardiac cell. 8 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 8, 2009 Washington People

James Kemp, M.D., began his medical career on the poorest Indian reservation in the country shortly after two high-profile incidents amplified tensions between the U.S. government and American Indians. In the mid-1970s, on the Pine Ridge Indian Reservation in southwest South Dakota, two separate confrontations between the government and activists known as the American Indian Movement left four FBI agents and three American Indians dead. As part of a U.S. Public Health BY BETH MILLER Service scholarship, Kemp went to the Indian Health Service at Pine Ridge in 1979 as a pediatri- cian fresh from residencies at SSM Cardinal Glennon Children's Medical Center in St. Louis and Baylor College of Medicine in . As a South Dakota native, Kemp felt called to serve in his home state. rr "Pine Ridge was a place with a long tradition of adventurous James Kemp, M.D. (right), talks with 10-year-old Darnell Yarbrough Jr., a patient in the Pediatric Sleep physicians who wanted to be in Diagnostics Laboratory and Sleep Disorders Clinic at St. Louis Children's Hospital. "Under (Kemp's) exciting places," says Kemp, pro- leadership, the pediatric sleep center and laboratory are becoming a regionally visible, interdiscipli- fessor of pediatrics and a pulmon- nary program, meeting the needs of the community and the medical center," says Thomas W. Ferkol, ologist at St. Louis Children's M.D., director of the Division of Allergy and Pulmonary Medicine and of the Cystic Fibrosis Center at Hospital. "It was very interesting, St. Louis Children's Hospital.

fun with what we're doing, and my their research, the American is treating children with sleep job is to see to it that the kid gets Academy of Pediatrics' Back to problems, such as obstructive The sleep doctor back to being a kid.'" Sleep campaign launched in 1994, sleep apnea, which occurs when Kemp took that attitude to encouraging parents to place their the upper airway narrows as the but it was dangerous also — it was heart, says Alan L. Schwartz, babies to sleep on their backs to muscles relax naturally during Kemp seeks roots a very violent place." Ph.D., M.D., the Harriet B. Spoeh- avoid suffocation from pillows, sleep. This reduces oxygen in the Some of the patients he saw rer Professor and head of the stuffed animals, comforters and blood and causes arousal from of kids' sleep were distrustful of him and the Department of Pediatrics. bumper pads in the crib. Because sleep. He is co-director of the other physicians at Pine Ridge. "Jim Kemp is a superior clini- of the campaign, Kemp says, most Pediatric Sleep Diagnostics disorders, sudden "They thought if we were any cian, a state-of-the-art expert in infant deaths no longer occur in Laboratory and Sleep Disorders good we'd be practicing in the both pulmonary diseases of chil- cribs — babies are dying from Clinic at the hospital. infant deaths suburbs someplace," he says. dren and sleep disorders, an en- sharing beds or couches with Kemp says removing tonsils But the reservation's people, gaging bedside teacher and a adults. and adenoids resolves the prob- the Oglala Sioux, had serious and critical thinker and scholar," "We have a situation in the lem in up to 80 percent of chil- complicated health problems that Schwartz says. "He is always ask- United States where SIDS is going dren. But the children he treats required good physicians. ing deep questions of pathophysi- down, but infant deaths are stay- are the ones whose problems "I'd done residencies in large ology and how to minimize dis- ing the same," Kemp says. "One don't improve after surgery. urban areas, and in this place, I ease burden on children." reason is the diminished impact "Some kids have terrible ob- saw every single problem I'd seen of Back to Sleep in high-risk structive sleep apnea due to obe- as a resident — congenital heart Sharpening the focus populations. Another reason is sity, big tonsils, craniofacial mal- disease, septic shock, premature After two years with the U.S. the high rates of bed sharing. formations and Down syndrome," births — but I was in the middle Public Health Service, Kemp Probably 70 percent to 80 percent he says. "Figuring out how to of a place where the nearest sub- entered private practice as a pe- of babies who die during sleep die address their clinical problems is stantial hospital was 120 miles diatrician in Mitchell, S.D. sleeping with their parents, and something that we're working on away," he says. "I was 29, and I Looking to specialize, he returned we're dealing with how to address here. It's rewarding, but also very was it." to Baylor College of Medicine and that now." challenging." Texas Children's Hospital for a In 2007, Kemp was named Much of the challenge is en- The inspiration three-year fellowship in pediatric co-leader of an $11 million grant couraging young children with Kemp's desire to become a pedia- pulmonary medicine, the start of from the Bill & Melinda Gates obstructive sleep apnea to wear James Kemp trician bloomed early in life. His his career as a "sleep doctor." Foundation funding a campaign CPAP (continuous positive airway mother, Peggy Kemp, now 84, was "I got into this area because I to prevent infant deaths from bed pressure) masks, which help to a nurse in a children's rehabilita- am interested in the control of sharing. The grant, awarded to keep the airway open while they Family: Wife, Debra, clinical tion hospital. breathing in babies," he says. "As a Baltimore-based First Candle, sleep. The only other option these research nurse coordinator in the "She taught me the impact on pulmonologist, I see lots of kids funds a pilot program in three children have is a tracheostomy, Center for Clinical Studies; son families when bad things happen with problems with breathing states that will distribute nearly or surgically cutting a hole in the Philip, a recent graduate of Columbia to kids and the importance of during sleep because of diseases 250,000 cribs to needy families throat. University in New York; son Patrick, those kids having fun in their like muscular dystrophy or ob- and educate them about the ben- Kemp gives much of the credit a junior at Macalester College in lives," he says. "When my brothers structive sleep apnea, cleft palate efits of using cribs. for getting children to use the St. Paul, Minn. and I would go to see her at work, and obesity." "Among poor families, the CPAP machines to the hospital's Hobbies: Travel, fishing and biking we saw how much fun she had Kemp came to the School of primary reason people sleep with staff on 7 East and in Child Life Senior rock groupie: Kemp unwinds with kids who were very unlucky." Medicine and St. Louis Children's their kids is they can't afford a Services. by going to small venues to listen to Kemp also was influenced by Hospital in 1989 as an instructor bed," he says. "There is also a "The Child Life staff has cre- rock bands. Some of his favorites one of his clinical professors at in pediatrics. He worked with controversy that bed-sharing is ated games parents can play with are Javier Mendoza, Dave Alvin and Creighton University School of Bradley Thach, M.D., professor of good because it promotes breast- their kids to get them to wear the the Guilty Men, The Blasters and the Medicine, Warren Bosley, M.D. pediatrics, studying sudden infant feeding, but there are other ways mask to sleep," he says. "That's Asylum Street Spankers. "When I did an elective with death syndrome (SIDS) and to increase rates of breastfeeding." the great thing about working at him, I saw how his attitude to- working in the new sleep lab at Kemp's colleagues say he is a St. Louis Children's Hospital Reading: "Traitor to His Class: The ward what he was doing was so St. Louis Children's Hospital. national leader in infantile apnea — you've got somebody whose Privileged Life and Radical lighthearted," he says. "His pa- Kemp and Thach studied how the with an infectious passion for job it is to do these kinds of things Presidency of Franklin Delano tients were sick, but his attitude sleep environment around a baby's teaching. that may seem goofy to those Roosevelt" by H.W. Brands was 'We're in this to serve the face might compromise the baby's "His seminal work with Brad caring for adults, but it's abso- patient, we're in this to have some breathing. Thach provided the mechanism lutely essential to being "Our approach to by which prone positioning led to successful." babies dying in the sudden infant death syndrome Kemp's success with his pa- prone (face down) and profoundly changed clinical tients is evident in a young cystic position was that they practice," says Thomas W Ferkol, fibrosis patient who recently weren't getting access to M.D., professor of pediatrics and graduated from high school with fresh air," he says. "If of cell biology and physiology, plans to become an engineer. But they were sunk down director of the Division of Allergy when that patient was in middle on a pillow, they would and Pulmonary Medicine and school, he was so unhappy that he be exchanging air only of the Cystic Fibrosis Center at considered dropping out of with the inside of the St. Louis Children's Hospital. school. pillow, leading to subtle "Under his leadership, the pediat- "I told him, 'I'm not going to suffocation." ric sleep center and laboratory are buy cystic fibrosis as an excuse for Kemp and Thach becoming a regionally visible, you not being a success,'" Kemp have worked with the interdisciplinary program, meet- recalls. "He is smart and 'worth it,' U.S. Consumer Pro- ing the needs of the community and I knew him well enough that ducts Safety Commis- and the medical center." I could talk that way. He didn't sion for many years to want to fall behind and drop out, develop safety stan- In the clinic either — he wanted to amount to dards for cribs and Although Kemp is renowned something. So he found a new infant bedding. nationwide for his research into school and blossomed. And that's The Kemp family: (from left) Debra, Jim, Patrick and Philip. Thanks in part to safe sleep practices, his main role why I do what I do."