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Washington University Record, October 8, 2009 Washington University School of Medicine Digital Commons@Becker Washington University Record Washington University Publications 10-8-2009 Washington University Record, October 8, 2009 Follow this and additional works at: http://digitalcommons.wustl.edu/record Recommended Citation "Washington University Record, October 8, 2009" (2009). Washington University Record. Book 1190. http://digitalcommons.wustl.edu/record/1190 This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Medical News: Hospitalist American Diary: Shimomurato Washington People: Kemp medicine divisions growing discuss paintings and performances 4 nationally recognized for SIDS work 8 ^Jfehington University in St Louis Oct. 8, 2009 record.wustl. Sleep loss linked to increase in Alzheimer's plaques BY MICHAEL C. PURDY ment of Neurology. "The results also suggest that Chronic sleep deprivation in a we may need to prioritize treating mouse model of Alzheimer's sleep disorders not only for their disease makes Alzheimer's many acute effects but also for brain plaques appear earlier and potential long-term impacts on more often, School of Medicine brain health," he said. researchers reported online in Holtzman's laboratory uses a Science Express. technique called in vivo microdi- Neurodegenerative disorders alysis to monitor levels of amyloid like Alzheimer's disease and beta in the brains of mice geneti- Parkinson's disease often disrupt cally engineered as a model of sleep. The new findings are some Alzheimer's disease. Amyloid beta of the first indications that sleep is a protein fragment that is the loss could play a role in the genesis principal component of Alzheim- of such disorders. er's plaques. The researchers also found that Jae-Eun Kang, Ph.D., a post- orexin, a protein that helps regu- doctoral fellow in Holtzman's lab, late the sleep cycle, appears to be noticed that brain amyloid beta Transcending bigotry through art, friendship A dialogue by alumni Michael Adams (left) directly involved in the increase in levels in mice rose and fell in and Gyo Obata drew a standing room-only crowd to Steinberg Hall Oct. 2.Their talk, titled brain plaques. association with sleep and wake- "Remembering the Internment," focused on the friendship between their famous fathers, the "Orexin or compounds it inter- fulness, increasing in the night, photographer Ansel Adams and the painter Chiura Obata (pictured), and how both families were acts with may become new drug when mice are mostly awake, and impacted by the U.S. government's internment of Japanese-Americans during World War II. The ...... decreasing during the day, when event was organized by the Center for the Study of Ethics & Human Values as part of the semes- targets for treatment of Alz- ter-long series "Ethnic Profiling: A Challenge to Democracy." Works by Ansel Adams and Chiura heimer's disease," said senior au- they are mostly asleep. Obata also are included in the exhibition "A Challenge to Democracy: Ethnic Profiling of Japanese thor David M. Holtzman, M.D., A separate study of amyloid Americans During World War II," on view in the Teaching Gallery of the Mildred Lane Kemper Art the Andrew and Gretchen Jones beta levels in human cerebrospinal Museum through Jan. 4,2010. Professor and chair of the Depart- See Sleep, Page 6 Forecast for discovered exoplanet: cloudy with a chance of pebbles BY DIANA LUTZ atmosphere is made up of the ingredients of Jupiter, which has 300 times the mass of miles, 23 times less than the distance be- rocks, and when a front moves in, pebbles Earth.) tween the parboiled planet Mercury and our So accustomed are we to the sunshine, condense out of the air and rain into lakes of COROT-7b, on the other hand, is less Sun. rain, fog and snow of our home planet molten lava below. than twice the size of Earth and only five Because the planet is so close to the star, that we find it next to impossible to imagine The work, by Laura Schaefer, research times its mass. it is gravitationally locked to it in the same a different atmosphere and other forms of assistant in the planetary chemistry labora- COROT-7b was the first planet found way the moon is locked to Earth. One side precipitation. tory in the Department of Earth & Planetary orbiting the star COROT-7, an orange dwarf of the planet always faces its star, just as one To be sure, Dr. Seuss came up with a Sciences in Arts & Sciences, and Bruce in the constellation Monoceros, or the side of the moon always faces Earth. green, gluey substance called oobleck that Fegley Jr., Ph.D., professor of earth and Unicorn. (This priority is designated by the This star-facing side has a temperature of fell from the skies and gummed up the planetary sciences, appeared in the Oct. 1 letter b.) about 2,600 Kelvin (4,220 degrees Fahren- Kingdom of Didd, but it had to be conjured issue of The Astrophysical Journal. Using the data from both planets, they heit). That's infernally hot — hot enough to up by wizards and clearly was a thing of Astronomers have found nearly 400 were able to calculate that COROT-7b has vaporize rocks. The global average tempera- magic. extra-solar planets, or exoplanets, in the an average density about the same as Earth's. ture of Earth's surface, in contrast, is only Not so with the atmosphere of COROT- past 20 years. But because of the limitations This means it is almost certainly a rocky about 288 Kelvin (59 degrees Fahrenheit). 7b, an exoplanet discovered last February by of the indirect means by which they are planet made up of silicate rocks like those in The side in perpetual shadow, on the the COROT space telescope launched by the discovered, most are Hot Jupiters, chubby Earth's crust, Fegley said. other hand, is positively chilly at 50 Kelvin French and European space agencies. gas giants — as large or larger than Jupiter Not that anyone would call it Earth-like, (-369 degrees Fahrenheit). According to models by Washington — orbiting close to their parent stars. (More much less hospitable to life. The planet and Perhaps because they were cooked off, University scientists, COROT-7b's than 1,300 Earths could be packed inside its star are separated by only 1.6 million See Exoplanet, Page 6 Nine years of helping needy with Give Thanks Give Back BY NEIL SCHOENHERR St. Louis-area residents struggling to overcome poverty. Now in its ninth year, Washington University's As the holiday season approaches, the news- Give Thanks Give Back campaign again will paper publishes the personal case stories of 100 help make the holiday season brighter for needy families or individuals. Although each of the St. Louis area families. 10,000 cases will receive some assistance, only a The annual event begins at 10 p.m. Thursday, small percentage of families are "adopted," Oct. 8, with a kick-off party at Ursa's Cafe in the meaning that an individual or group agrees to South 40. In addition, students will be manning buy gifts, clothing, household appliances or tables and handing out information outside the other requested items for the family. Danforth University Center from 11 a.m.-l p.m. Members of the University community Tuesday, Oct. 13, and Wednesday, Oct. 14. normally adopt around 120 families each year, "Give Thanks Give Back is a fun and afford- which amounts to more than 300 individuals. able way for students, faculty and staff to help "All of these families live in the area and have out the St. Louis community during the holiday fallen on hard times due to a layoff or injury," season," said senior Lynn Wilkie, a psychology Wilkie said. "We connect students and faculty major in Arts & Sciences and co-chair of this to the families who need assistance, and then year's Give Thanks Give Back student group. the sponsors go shopping for clothing, house- Give Thanks Give Back supports a group hold supplies or educational toys, depending on called "100 Neediest Cases," a joint project of the needs of the family. the St. Louis Post-Dispatch and the United Way. "It's a great way to locally make a difference During the holiday season, the 100 Neediest in someone's life, and we are always amazed and Students help wrap gifts last November for needy families with the annual Cases identifies more than 10,000 cases of See Give Back, Page 2 Give Thanks Give Back campaign. 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Creating a culture of integrity BY KURT MUELLER evidenced by corporate scandals, doping by professional athletes David Callahan, Ph.D., public and plagiarizing. He puts the policy activist and scholar of blame on the ruthlessly competi- academic integrity, will present tive economic climate of the past "Creating a Culture of Integrity" two decades and claims that the at 11 a.m. Thursday, Oct. 15, in "winning" class has enough mon- Graham Chapel. ey and clout that they can cheat His talk is the keynote address without consequences, while the of The Center for Academic "anxious" class believes that cheat- Integrity's 18th Annual Inter- ing is the only way to succeed in a national Conference (see below) winner-take-all world. and is being co-spon- Callahan is a co- sored by the Assembly founder of Demos, a Series and the Center public policy center based for Ethics and Human in New York.
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