Leader in Niche Scientific Graphing Sigmaplot 12

Exact Graphs and Data Analysis

Leader in Niche Scientific Graphing SigmaPlot 12

Analyze and Graph your Data with Unparalleled Ease and Precision

SigmaPlot® is a scientific data analysis and graphing software package with advanced curve fitting, a vector-based programming language, macro capability and over 50 frequently used statistical tests. SigmaPlot has the analytical features necessary to extract the important information from your research data. With over 100 graph types and a user interface which allows detailed manipulation of every graph object, you can create the exact graph to present your results.

Complete Advisory Statistics Create the Exact Graph Powerful Curve Fitting Advanced Analysis Methods for Scientists & Engineers for your Research Nonlinear, Dynamic and Global Bland-Altman, Dot Density, Over 50 tests with complete Over 100 different 2D and curve fitting and Enzyme Kinetics background statistical assumption 3D graph types in the now implicit testing and appropriate Create Graph ribbon function fitting test suggestion

Tabbed Groups Collect related graphs in a tabbed group for easy relationship to a worksheet

Object Window Objects are identified when clicked on in the Notebook Manager graph Save multiple notebooks, worksheets, graphs, reports, transforms, equations and macros Properties Window The properties associated with the selected object. Dynamic Update changes Interactive Graph Wizard the graph immediately. A step-by-step graph creation No clicking Ok or process Apply required.

Huge Worksheet and Associated Multiple Methods for Zoom, Work Directly on the Page Programming Language Pan and Drag Almost every object is selectable. 32,000,000 rows & 32,000 Press the spacebar and drag the graph with Mini-toolbars allow direct columns. Vector based the hand cursor. Use the slider for large modification. computations. zoom changes or the buttons for 10% changes.

Fine Tune Every Graph Detail Create Your Exact Graph in No Time Data Analysis Methods to Uncover Information in your Data The beauty and utility of SigmaPlot Create compelling graphs for publications, Over 50 of the most frequently used is its ability to modify each graph presentations and reports statistical tests with step-by-step object to produce a graph that in Let the Interactive Graph Wizard lead you directions that do not require you to be total “tells the story” of your through every step of graph creation a statistician research. Choose from over 100 different 2D and Fit your data easily and accurately with 3D graph types the Regression Wizard, Dynamic Fit Control and customize the properties of Wizard and Global Fit Wizard. And now every graph element fit implicit functions Use Dynamic Update to draw your graph Plot mathematical functions with the Exact Graphs and Data Analysis immediately after a property change function plotter Use the Macro recorder to automate repetitive and complex tasks

Download Trial Version at www.sigmaplot.com SigmaPlot 12

Generate Graphs Quickly and Easily with the New Interface Features

Microsoft OfficeTM Style Ribbons Ribbons provide context sensitive feature groupings for enhanced functionality and ease of use. Icons are now high resolution and have expanded tooltips containing hot keys. Keyboard shortcuts are provided by the Alt Key-Tips.

Create Graph Tab Toolbox Tab

Graph Page Tab

Report Tab Worksheet Tab

New Property Browser All the properties for a graph and its objects are contained in the Property Browser. You select and modify the properties there and the Dynamic Update feature updates the graph immediately – you don’t have to click Ok. For example the graph to the right shows the properties for a diagonal-gradient bar fill starting from red and ending at blue with transparency used for both colors. Property group styles may be copied and applied across like groups thus simplifying property specification.

User Interface Features

Tabbed Window View Open Window Tabs Selected Tab Now in SigmaPlot all open windows appear with tabs. Click on a window tab for an instantaneous display of each window. It is an efficient window management tool.

Mini Toolbars Quick Access Toolbar Mini-Toolbars are Group / Now you can add commonly used controls to displayed on the Bring to front Ungroup SigmaPlot’s Quck Access Toolbar such as graph when you select an object or right click on it. You can make quick Creating a new notebook modifications Insert Text Fill Color Saving changes in a notebook directly Cleaning up the workspace by closing all on the graph. windows

Download Trial Version at www.sigmaplot.com SigmaPlot 12

New Graphing Capabilities Enhance Your Ability to Create Publication-Quality Graphs

New Graph Features

The use of Horizontal color transparency gradient used for a visual for impact. histogram of overlapping data values.

Color gradient and transparency. The transparency allows comparing the area size of both radar plots. The gradient enhances the graph.

Dot Density The dot density plot is a graphical histogram of your data. The SigmaPlot dot density is very much like what an artist would prepare where adjacent data values either stack or nestle. The graph shows dot densities of three data sets with percentiles displayed – one of the statistical options available.

Radar Graph Radar graphs can display multiple variables. This graph allows an eight variable comparison of three data sets.

Scale Graph Original Zoom 5x The ScaleGraph macro allows zooming and panning through a long time series or data sequence. So, for example, zooming in by 5x followed by panning 90% to the left two times produces Pan Left the graph right which shows fine detail of the first two peaks. 90% Twice

Download Trial Version at www.sigmaplot.com SigmaPlot 12

Effectively Manage and Analyze Your Data with the New Analysis Features

New Analysis Features

Enzyme Kinetics The Enzyme Kinetics module is now integrated into SigmaPlot providing you with additional enzyme kinetics analysis features and additional graph types such as Michaelis-Menten, Lineweaver-Burk, Eadie-Hofstee, Scatchard, Hanes-Woolf, Hill and Dixon

Curve Fitting Features Weight variables that are functions of the parameters may now be used. This includes weighting by predicted values, robust fitting and weighting by any parameter function. Parameter covariance matrix and confidence intervals have been added to nonlinear regression reports. Implicit function curve fitting-the ability to compute predicted values that are defined implicitly by the fit model. Deming Graph

Statistics Non-parametric One Deming regression method Sample t-test comparison (account for error Method 2 in both x and y)

Method 1

Normal distribution comparison produces a visualization of the distributions of up to four measured variables to quickly detect and demonstrate possible product defects.

Parallel line analysis to Bland-Altman graph determine and statistics if linear for method regression slopes comparison. and intercepts are different.

Transform Language Row and column titles may now be set with a Transform language statement New functions for root finding and equation solving which includes a function to help solve fit models that are defined implicitly

Download Trial Version at www.sigmaplot.com SigmaPlot 12 Features Legends • Running median • Draw lines, ellipses, boxes, arrows • Automatic or manually created; lines and symbols on or off • Bisquare • Layering options GRAPHING FEATURES • Legends for regressions, confidence, and prediction intervals • Inverse square • Over 16 million custom colours • Place line and symbol before or after text • Inverse distance (for 3D smoothing) • Inset graphs inside one another 2D TRANSFORMS • Selection of graph objects • Radar - 5 Types* Function Plotter • Right-click property editing • Dot Density - 4 Types* • Automatic or manually created; lines and symbols on or off Quick Transforms • Colour schemes • Vector - 2 Types • Plot functions on new or existing graphs • Perform quick mathematical transforms provided in a • Paste graphic objects from other programs • Area Plots - 4 Types • Plot multiple different parameter values simultaneously function palette • Graph page rulers • Scatter - 14 types, Line - 4 types, Scatter and Line - 10 types • Equation Solver: solve equations or functions containing a • Automatic Updating of multiple transforms in worksheets • Adjustable snap-to grids • Step - 8 types single independent variable and any number of parameters • Mathematical Transforms Vertical and Horizontal Bar - 4 types, Grouped Bar - 4 types "Picking from Column" Option • Vertical and Horizontal Stacked Bar NEW USER INTERFACE FEATURES* • Set worksheet row and column titles* • Enter colours, patterns, symbols, line styles, tick mark • Box - 2 types • Root() and Implicit() functions* • Microsoft Office Style Ribbons* intervals, tick labels and more directly into your worksheet Polar - 3 types • 36 probability density and cumulative transforms • • Context sensitive feature grouping for enhanced functionality to customise your graph the way you want. Transforms Contour, line and filled - 2 types • Histogram • and ease of use and "picking from column" allow you to create data Histograms - 6 types • Normalise ternary data • • Expanded tooltips that include hot keys dependent colour gradients, symbols and sizes. Ternary - 3 types • Interpolate 3D mesh • • Alt Key Tips provide visual display of keyboard shortcuts Bubble • Sorting • Automate Routine and Complex Tasks Pie New Property Browser* • Fast Fourier transforms with filters • Control Charts • New graph object and property browser. Object selection in the • Lowess smoothing • Visual Basic compatible programming using built-in • Needle graph is displayed in the object window and the object’s properties • Differential equations macro language interface • displayed in the property window. High-low-close, Range, Quartile • Data to RGB-colour transform • Macro recorder to save and play-back operations • • Dynamic Update provides immediate graph redraw with property • Quadrant • Trigonometric and algebraic functions Full automation object support - use Visual Basic to • Population change. No Ok or Apply button press required create your own SigmaPlot-based applications • Property group styles may be copied and applied across like • Random and Gaussian random number generation 3D • Range, accumulation, precision, and more • Run built-in macros or create and add your own scripts groups thus simplifying property specification. • Add menu commands and create dialog boxes • Multiple, intersecting plots with hidden line removal, • New window show/hide buttons for window real-estate management • Transforms are now kept in notebook files as JNB files for smooth or discrete shading, transparent or opaque fills, easier organisation of transforms; create transform libraries; • Export graph to PowerPoint Slide User Interface Improvements* and light source shading associate Transforms with data sets • New 'Insert Graph to Microsoft Word' Toolbox macro • New tabbed window views enables quick window management • • 3D rotation (selection, closing, grouping) Protect and track changes to transforms for 21 CFR Part 11 • New keyboard shortcuts in the Graph Properties and most • Perspective preview Microsoft Excel keyboard shortcuts in the worksheet • New docking panel guides providing simple window placement. GENERAL FEATURES • Scatter • Macro language graph page measurement units specification* This includes the Graph Gallery, Templates, Layouts, Object Large, Scientific Worksheets • Bar and Properties windows • Macro language automatic legend state specification* • • 32,000 columns by 32,000,000 rows 3D line - trajectory • Group open windows into tabbed groups either vertically or • Mesh - with or without contour projections • Handles numeric, text (categorical), and date & time data horizontally. This collects like windows for easy comparison and Windows Application • Contour better window management • Data sorting • • Waterfall • Object-specific mini toolbars are displayed adjacent to selected Insert colour, symbols, line styles and bar patterns • Excel, Word and PowerPoint for Office 2000 and graph, worksheet and report objects. This allows rapid editing of • Independent graphically adjustable row height and column widths Windows 2000 support ToolTips Create Graphs Easily object properties • Missing data handling • Tips and Tricks at startup • Graph Style Gallery: Save any graph with all graph • Customizable Quick Access Toolbar for frequently used • Data point sampling • OLE 2 container and server properties and add a bitmap image to the gallery to recreate user-specific controls • Graphical feedback of current curve and datapoint • Use Excel worksheets inside SigmaPlot complex graphs • Text support of up to 256 characters • Right mouse button property editing • DATA ANALYSIS FEATURES Graph Ribbons: select ribbon icon of the graph type and style • Change the font type and grid colours • Selection of objects on graph page Enzyme Kinetics Module* you want to create a graph or to add additional curves to an • Change font for worksheet • Full precision and date/time Microsoft Excel copy and paste existing graph • Analyze multiple models and rank by best fit • Multiple Undo • Graph Wizard: easy to use, step-by-step wizard for helping • Create multiple enzyme kinetics graphs: Michaelis-Menten, • Format empty cells - formatted selected columns even if they IMPORT & EXPORT OPTIONS you select a graph type and pick data Lineweaver-Burk, Eadie-Hofstee,Scatchard, Hanes-Woolf, Hill, Dixon do not contain data • Default graph settings: set preferences for graph options to • More flexible column titles allow for duplicates and numeric only titles Import create favorite graphs more easily Regression Wizard • Enhanced data/time recognition and more formats • Directly import SAS data sets (.sd2 and .sas7bdat files) • • Templates: create custom graph page templates to store for Linear and nonlinear regressions • Arrow-key functionality is similar to that of Microsoft Excel • Directly import Minitab data sets (.mtw & .mpj files) • easy accessibility and future use Over 100 built-in, graphically-illustrated equations • Freeze Panes and print preview • Open Axon Binary, Axon Text, ASCII Plain, Comma and • Marquardt-Levenberg algorithm with up to 10 • general import filter, 1-2-3TM, Symphony TM, Quattro TM, Excel, Technical Axes Multi-line editing - text wraps to fit the column while the independent variables and 100 parameters row height automa tically adjusts dBASE E, DIF, all SigmaPlot files through SigmaPlot 11, • Reciprocal (including Arrhenius) • Define tolerance, step size and iterations • SigmaStat files (all versions), SYSTAT, SigmaScan Pro, • Weibull Find and replace data • Define linear constraints and fix parameters to a constant value Sigma Scan, SigmaScan Image, Mocha • Linear • Mini-toolbar for worksheet cell editing* • Automatically determines your initial parameters • Import any ODBC compliant database • Log10, Natural log • Zoom enabled worksheet* • Writes a complete statistical report to your SigmaPlot Notebook • Run SQL queries on tables and selectively import • Probit • Quick Transforms list in Property Browser Object Window* • Automatically graphs your results on new or existing graphs • Quick worksheet window scrolling with middle mouse wheel* information • Logit • Option to add 95 or 99% confidence and prediction bands to a • Probability • Formatted text in worksheet cells. Text in worksheet can Export results graph contain super and subscripts, Greek letters, etc. and this can be • SAS files (.sd2 and .sas7bdat files) • Ternary percentage, unary • Optional Reduced Chi-Square Regression weighting used in tick labels* • Minitab files (.mtw & .mpj files) • Polar (both clockwise and counter clockwise) • Customize the SigmaPlot fit library or create your own fit functions • ASCII Text, Tabbed, Comma, 1-2-3TM, Excel, DIF, all • Category (text data automatically binned into groups) • SigmaPlot Notebook Manager Generalized weight variables: predicted values, robust regression* SigmaPlot files though SigmaPlot 11, SigmaScan Pro • Time and date • Holds SigmaPlot worksheets, Excel worksheets, reports, regression • Parameter covariance matrix and confidence intervals in report* • PDF, PSD and HTML export of graphs and reports • User-defined custom axis to create almost any scale wizard equations, graph pages, transforms and macros • Predicted values defined implicitly by the fit model* • Direct-editing of notebook summary information Import Graphics Options Axis Features Dynamic Fit Wizard • Load popular graphic file formats directly into SigmaPlot • Control of display, thickness, colour, range, and axis offset SigmaPlot Report Editor • Solves difficult curve fitting problems by finding local and global graphic page • Multiple axes: Add Axis Wizard for creating multiple axes easily fit solutions • Insert tables with pre-defined styles or customize completely* • Import BMP, JPEG, GIF, TIFF, Cursor and Icon Files & many more • Ticks: customize major & minor intervals, in & out orientation, • Selects many initial maximally-distant starting parameter sets • Copy/Paste tabular data both ways between the SigmaPlot top & bottom location, length, thickness, colour, and tick mark and ranks the resulting fits report and Excel worksheet* selection from column to create custom axes Graph Publication Export Options • Shows the local minima with a Dynamic Fit Profile graph • Zoom enabled report* • Tick Labels: customise prefix, suffix, numeric, and time & date • Vertical and horizontal rulers* • Export an individual graph, a group of graphs and objects, • Axis breaks: customize symbol, thickness, colour, length, Global Fit Wizard • Ability to change the report background color* or an entire page • Different levels of resolution and colour depths:PDF, EPS, gap width, and post break interval • Fit multiple data sets using shared parameters • Enhanced PDF export* TIFF, JPEG, EMF, BMP Symbol Line and Fill Types Automatic Linear Regressions • Drag and Drop Word 2007 and Word 2010 content directly to • Over 80 symbol types the report* • True colour EPS vector and CMYK EPS export • Up to 10th order with confidence and prediction intervals • Compressed CMYK TIFF • More line types for line plots and line scatter plots, and regression statistics • Cut and paste or use OLE to combine all the important aspects free-form lines, boxes and ellipses of your analysis into one document. • 50 fill patterns for bar charts, box plots, pie charts, Column Descriptive Statistics Generated Automatically • Choose from a wide range of styles, sizes, and colours Publish as Web Page area plots and free-form boxes and ellipses from any system font. • Export graphs as high-resolution Web objects STATISTICS • • WebViewer: free browser plug-in to view data used to create Error bars Export to most word processors • Over 50 of the most frequently used statistical tests to analyze scientific data • graph or print, pan and zoom in on graph without • Mean, Median, First and Last values for symbols Add decimal tabs, tab leader, true date/time fields • Advisor Wizard guides you through the process of choosing the • losing resolution • Standard deviation, Standard error, Min and Max, First and Last entry Auto-numbering appropriate statistical test • The WebViewer supports IE 4.01 or higher. A screen resolution • 10th, 25th, 75th, and 90th Percentile, 95% or 99% confidence Page Layout and Annotation Options • Report generation that translates the statistics into plain and simple English JPEG file is automatically displayed for browser applications • Calculate error bars from replicate values across rows • Zoom, pan, +/- controls and zoom dialog & slider always • Descriptive statistics available on status bar* and operating systems • User-defined upper and lower error bar values • Non-parametric tests: t-tests, ANOVA • • Drag graph with "hand" mouse cursor* One way, two way and asymmetric error bars • One-way, two-way, three-way ANOVA • • Quick window scrolling with middle mouse wheel* SYSTEM REQUIREMENTS Percentile method: 2-types • Repeated measures • Direct graphic file import into graph page • Windows Vista, Windows 7 : Multiline Text Editor • Rates and proportions • Real-time mouse-over XY and page coordinate feedback • Control font, size, style, colour, Greek, multiple levels of • Regression, including Linear, Stepwise, Best Subsets, Polynomial and Logistic • Click-through accessibility to select and edit graph objects - 1 GHz 32-bit (x86) or 64-bit (x64) processor superscript & subscript, 360 degree rotation, left, right • Correlation buried under other items - 1 GB of system memory & center justification, and line spacing • Survival analysis (Kaplan-Meir, Cox Regression) • OLE 2 container and server - 100 MB of available hard disk space - CD-ROM drive Grids and Fills • Power and sample size analysis • Automatic or manual legends • One-sample signed rank test* • True WYSIWYG - 800x600 SVGA/256 colour display or better • Control of colour, line type, thickness, and display of major & - Internet Explorer 6 or higher minor grids in X, Y, & Z direction • Deming regression for errors in both x and y* • Multiline text editor • Multiple curves and plots on one graph • Control of pattern and edge colour, pattern style, pattern • Normal distribution comparison for QC analysis* • Windows XP : density, and edge thickness Symbols • Multiple axes on one graph • Parallel line analysis* • Arrange graphs with built-in templates - 500 megahertz (MHz) processor, - 256 MB of system memory, Reference Lines • Bland-Altman analysis for method comparison* • Multiple levels of zooming and custom zooming - 100 MB of available hard disk space • Control mean, standard deviation, standard error, user-defined • Easily change the size and position of multiple selected - CD-ROM drive, constants, 95% and 99% confidence intervals SMOOTHING objects simultaneously to lay out and arrange graphs • Up to 5 horizontal or vertical lines - 800x600 SVGA/256 colour display or better 2D & 3D Smoothing Routines and other objects quickly - Internet Explorer 6 or higher • Control of colour, line type, and thickness • Negative exponential • Scale graph to any size Drop lines • Running average • Resize graphic elements proportionally with resizing graph • Display in any or all X, Y, and Z directions • Loess • Alignment and position tools * New Features added in SigmaPlot 12

For more information, visit us at www.sigmaplot.com Exact Graphs and Data Analysis

North, Central & UK and Ireland : Germany and Austria : Asia-Pacific : South America : Systat Software Inc. Systat Software GmbH. Cranes Software International Ltd. Systat Software, Inc. 4th Floor, Block B, Vista Centre, Schimmelbuschstrasse 25, #29, 7th Cross, 14th Main 1735, Technology Drive, Suite 430, 50, Salisbury Road, D-40699, Erkrath, Germany Vasanthnagar, Bangalore - 560 052 San Jose, CA 95110 USA Hounslow, TW4 6JQ, London, UK Phone: +49.2104.9540 Karnataka, INDIA. Phone : 800-797-7401 Phone : +44-(0)208-538 0128 Fax: +49.2104.95410 Phone : +91 - 80 - 4151 6400 Fax : 800-797-7406 Fax : +44-(0)208-538 0273 e-mail: [email protected] Fax : +91 - 80 - 4151 6500 e-mail : [email protected] e-mail : [email protected] e-mail : [email protected]