Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_002334685Cyc: Desulfovibrio sp. G11 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

ammonium ammonium ammonium glycine betaine ammonium pro

RS10110 RS07190 RS03355 RS01295 RS01735

glycine betaine ammonium ammonium ammonium ammonium pro

Nucleoside and Nucleotide Degradation Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Glycolysis Cofactor, Prosthetic Group, Electron Carrier Degradation a nascent peptidoglycan UDP-N-acetyl- DNA combined (2R,3S)-3- (R)-2- purine nucleotides degradation II (aerobic) a malonyl-[acp] D-ribulose 5-phosphate a [DsrC]-S- formate UTP (S)-NADPHX cob(II)yrinate a,c-diamide glycolysis I (from glucose 6-phosphate) O-acetyl-L-serine hydrogen selenide with (L-alanyl-γ-D- a malonyl-[acp] α-D-muramoyl- di-trans,octa-cis with exogenous isopropylmalate hydroxyglutaryl- phe DMAPP superpathway of thiamine diphosphate biosynthesis I tetrapyrrole biosynthesis thiamine salvage II NAD folate polyglutamylation Aminoacyl-tRNA Charging vitamin B degradation lipid II (meso methyl ester GTP sulfanyl-L-cysteine formate ATP biosynthesis II (late I (from glutamate) 6 O-acetylhomoserine glutamyl-meso-2,6- ketoacyl-ACP L-alanyl-γ-D- -undecaprenyl 3,4-dihydroxy- DNA to form a dissimilatory- ribonucleoside- 3-isopropylmalate CoA bifunctional 4-hydroxy- phosphorylation and diaminopimelate bifunctional 2-hydroxyglutaryl- aspartate ribonucleoside- cobalt incorporation) aminocarboxypropyltransferase/ diaminopimeloyl- synthase III: glutamyl-L-lysyl- phospho-N-phosphate 2-butanone- recombinational type sulfite triphosphate dehydratase ADP-dependent 3-methylbut- 4-amino-2-methyl-5- transhydrogenation D-glucopyranose 6-phosphate AMP containing) Holliday junction 3,4-dihydroxy- CoA dehydratase: aminotransferase: triphosphate uroporphyrinogen-III cys a tetrahydrofolate tRNA charging pyridoxamine pyridoxine cysteine synthase: D-alanyl-D-alanine) peptidoglycan CNY67_RS04875 D-alanyl-D-alanine acetylmuramoyl- 4-phosphate junction reductase reductase: large subunit: NAD(P)H-hydrate 2-enyl Glu pyrimidinemethanol glutaminyl-tRNA gln resolvase RuvX: CNY67_RS07920 CNY67_RS01635 reductase: NAD + pentapeptide glycosyltransferase: synthase: ribB 2-butanone- subunit CNY67_RS11850 dehydratase/ diphosphate uroporphyrinogen-III bifunctional biosynthesis via 5'-nucleotidase CNY67_RS06365 3-oxoacyl-[acyl- pentapeptide- CNY67_RS00165 CNY67_RS05955 2-hydroxyglutaryl- aspartate/ CNY67_RS05955 cysteine ATP-NAD/ glucose-6-phosphate CNY67_RS09500 4-phosphate alpha: dsrA 3-isopropylmalate NAD(P)H-hydrate reductase: C-methyltransferase: hydroxymethylpyrimidine bifunctional serine formate--tetrahydrofolate arg arginine-- transamidation SurE: O-acetylhomoserine carrier-protein] undecaprenyl-transferase: bifunctional crossover junction ribonucleoside- CoA dehydratase: tyrosine/aromatic desulfurase AcoX kinase: isomerase: penicillin- synthase/GTP dehydratase ribonucleoside- epimerase: ispH cobA an L-glutamyl- kinase/ tetrahydrofolate synthase/ hydroxymethyltransferase: glyA ligase: CNY67_RS08565 tRNA ligase: CNY67_RS00725 aminocarboxypropyltransferase/ reductase: diphospho-CNY67_RS06695N- 3,4-dihydroxy- resolution ofendodeoxyribonuclease a [DsrC protein] with[+ 3 isozymes] triphosphate CNY67_RS11580 aminotransferase: (E)-4-hydroxy-3- NifS: nifS CNY67_RS07285 CNY67_RS09965 binding cyclohydrolase II: small subunit: leuD triphosphate CNY67_RS07165 siroheme synthase: [tRNA Glu ] phosphomethylpyrimidine dihydrofolate synthase: CNY67_RS10515 an L-arginyl- Glu cysteine synthase: CNY67_RS04870 acetylmuramoyl- 2-butanone- RuvC: CNY67_RS10530 reductase: (E)-glutaconyl- methylbut-2-en- an [L-cysteine NADP + a nascent peptidoglycan recombinational 2,5-diamino-6-CNY67_RS01405 an intramolecular sulfite (2S)-2- CNY67_RS03680 reductase: Arg pyridoxal protein a 3-oxoglutaryl- UMP γ 4-phosphate CoA keto- NADPH CNY67_RS05845 desulfurase]-S- kinase: thiD CNY67_RS03760 10 [tRNA ] adenosine CNY67_RS09360 γ acyl-carrier protein L-alanyl- -D- junction disulfide bond CNY67_RS13190 1-yl diphosphate a 5,10-methylenetetrahydrofolate an N -formyltetrahydrofolate Arg with (L-alanyl- -D- (5-phospho-D- isopropylmalate CNY67_RS13190 precorrin-1 glutamyl-tRNA a tRNA F6P di-trans,octa-cis 2: mrdA [acp] methyl ester synthase/GTP dUTP phenylpyruvate sulfanyl-L-cysteine a ThiS sulfur- pyridine nucleotide 3-oxoacyl-[acyl- acetate L-selenocysteine glutamyl-meso-2,6- glutamyl-L-lysyl- formation of two formate ribosylamino) reductase: HMP-P an L-glutamyl- -undecaprenyl cyclohydrolase II: dATP cysteine :[Thil sulfur- carrier protein transhydrogenase bifunctional bifunctional adenosine carrier-protein] diaminopimeloyl- D-alanyl-D-alanine intact strands pyrimidin- uroporphyrinogen-III CNY67_RS05835 a tetrahydrofolate Gln IMP CNY67_RS01405 protein cysteine] 5-(2-hydroxyethyl) subunit alpha: tetrahydrofolate synthase/ tetrahydrofolate synthase/ [tRNA ] fructose-1,6- deaminase: diphosphate 4(3H)-one C-methyltransferase: (S)-4-amino-5- bifunctional 6-phosphofructokinase: reductase: D-alanyl-D-alanine) sulfurtransferase: -4-methylthiazole CNY67_RS13700 dihydrofolate synthase: dihydrofolate synthase: glutamyl-tRNA bisphosphatase: CNY67_RS04920 1-deoxy-L-glycero- cobA oxopentanoate hydroxymethylpyrimidine CNY67_RS12630 GMP IMP CNY67_RS04870 pentapeptide formate nifS hydroxyethylthiazole CNY67_RS03760 CNY67_RS03760 cysteine-- amidotransferase: CNY67_RS07870 tetrulose 4-phosphate kinase/ [+ 3 isozymes] cys nicotinate-nicotinamide dehydrogenase: precorrin-2 a [ThiI sulfur- a carboxy- glutamate-1- kinase: tRNA ligase: CNY67_RS06585 4-pyridoxolactone D-glyceraldehyde phosphomethylpyrimidine 10 nucleotide 5'-nucleotidase AIR carrier protein]-S- adenylated-[ThiS semialdehyde CNY67_RS12070 NADPH a 5,10-methylenetetrahydrofolate an N -formyltetrahydrofolate β CNY67_RS03390 3-phosphate CNY67_RS06045 an L-cysteinyl- -D-fructose 1,6-bisphosphate adenylyltransferase: SurE: precorrin-2 C(20)- tyr sulfanyl-L-cysteine sulfur-carrier protein] 2,1- kinase: thiD 4-methyl-5-(2- an L-glutaminyl- a DNA containing α UDP-N-acetyl- a ribonucleoside a [DsrC a negatively Cys Gln DHAP O-acetyl-L- a glutaryl-[acp] adenosylcobinamide- -ribazole formate CTP sulfite L-cysteate phosphomethylpyrimidine 1-deoxy-D- [tRNA ] [tRNA ] CNY67_RS12230 CNY67_RS00725 XMP methanethiol an apurinic/ a malonyl-[acp] α-D-muramoyl- di-trans,octa-cis cobalt-precorrin-7 formate protein]-dithiol supercoiled DNA (S)-NADHX IPP methyltransferase: aminomutase: phosphooxyethyl) Cys fructose-1,6-bisphosphate homoserine methyl ester GDP 5'-phosphate triphosphate dITP formate GTP synthase ThiC: 2-iminoacetate xylulose-5- HMP-PP di-trans,poly-cis a tRNA apyrimidinic site L-alanyl-γ-D- -undecaprenyl bifunctional cobalt- dissimilatory- DNA aspartate bifunctional cobI hemL thiazole aldolase, class II: fba O-acetylhomoserine endonuclease ketoacyl-ACP cobalamin ribonucleoside- ribonucleoside- 4-hydroxy- CNY67_RS11120 synthase ThiH: phosphate -undecaprenyl inosine guanosine glutamyl-L- phosphate precorrin-7 (C(5))- XTP/dITP diphosphatase: type sulfite topoisomerase 1: aminotransferase: ribonucleoside- ADP-dependent Fatty Acid and Lipid Biosynthesis triose-phosphate 5'-nucleotidase 4-pyridoxate aminocarboxypropyltransferase/ III: nth synthase III: synthase: phospho-N- triphosphate triphosphate 3-methylbut- precorrin-3A CNY67_RS01250 synthase: dxs 5-aminolevulinate phosphate biosynthesis fructose-bisphosphate lysyl-D-alanine methyltransferase CbiE/ CNY67_RS02735 reductase CNY67_RS13455 CNY67_RS01635 triphosphate NAD(P)H-hydrate thiamine lipoate salvage I thiamine diphosphate bis(guanylyl molybdenum isomerase: SurE: cysteine synthase: CNY67_RS04875 CNY67_RS14325 acetylmuramoyl- reductase: reductase: 2-enyl HMP-P a thiocarboxy- (2E,6E)-farnesyl aldolase: CNY67_RS12565 purine-nucleoside purine-nucleoside bifunctional DNA- decarboxylating cobalt- nucleoside triphosphate subunit reductase: dehydratase/ 2-iminoacetate 1-deoxy-D-xylulose phosphate IPP biosynthesis cofactor) biosynthesis palmitate biosynthesis II (bacteria and plants) CNY67_RS07980 CNY67_RS00725 CNY67_RS06365 3-oxoacyl-[acyl- [+ 5 isozymes] pentapeptide- CNY67_RS13190 CNY67_RS05955 DNA aspartate/ diphosphate [ThiS-Protein] porphobilinogen diphosphate glutamine-- phosphorylase: phosphorylase: formamidopyrimidine precorrin-6B (C(15) pyrophosphohydrolase: alpha: dsrA CNY67_RS05955 NAD(P)H-hydrate bifunctional 5-phosphate synthase: thiE isoprenyl II (Bacillus) MoO - palmitoleate CDP-diacylglycerol O-acetylhomoserine carrier-protein] adenosylcobalamin undecaprenyl-transferase: ribonucleoside- ribonucleoside- topoisomerase I: tyrosine/aromatic reductase: synthase: tetrahydrofolate biosynthesis (R)-lipoate 2 tRNA ligase/ CNY67_RS12110 CNY67_RS12110 glycosylase/ GMP )-methyltransferase CNY67_RS11565 ribonucleoside- epimerase: hydroxymethylpyrimidine transferase: molybdopterin biosynthesis I (from biosynthesis III xanthosine 5-formyl-3-hydroxy-2- aminocarboxypropyltransferase/ reductase: 5'-phosphate diphospho-CNY67_RS06695N- triphosphate triphosphate [+ 3 isozymes] CNY67_RS13935 aminotransferase: (E)-4-hydroxy-3-ispH thiazole synthase: CNY67_RS13550 di-trans,octa-cisCNY67_RS11785 lipoyltransferase HMP-PP YqeY domain an acetoacetyl-[acp] (5Z)-dodec-5-enoate) DNA-(apurinic or CbiT: CNY67_RS02240 dIMP CNY67_RS03680 triphosphate CNY67_RS07165 precorrin-3B kinase/ (7,8-dihydropterin- and lipoate- thiamine cofactor bis(molybdenum D-glyceraldehyde 3-phosphate methylpyidine-4-carboxylate cysteine synthase: apyrimidinic site) lyase: CNY67_RS04870 acetylmuramoyl- reductase: reductase: a [DsrC]-trisulfide a relaxed DNA methylbut-2-en- CNY67_RS01255 thiamine phosphate -undecaprenyl fusion protein: an acyl-[acyl- hypoxanthine guanine a 3-oxopimeloyl- UMP reductase: phosphomethylpyrimidine porphobilinogen 6-yl)methyl 4-aminobenzoate protein ligase: phosphate cofactor) synthase: a (5Z)-dodec- CNY67_RS09360 CNY67_RS03415 acyl-carrier protein L-alanyl-γ-D- cobalt-precorrin-8 CNY67_RS05955 CNY67_RS13190 3-sulfopyruvate NADH 1-yl diphosphate diphosphate CNY67_RS08465 3-oxoacyl-[acyl- DHAP carrier protein] [acp] methyl ester a 2'-deoxyribonucleoside CNY67_RS13190 kinase: thiD 2-[(2R,5Z)-2-carboxy- thiamine- diphosphate CNY67_RS10310 synthase: bis(molybdenumCNY67_RS11555 5-enoyl-[acp]ketoacyl-ACP type I glyceraldehyde- purine-nucleoside acetate met a 3'-terminal a 5'-phospho- glutamyl-L- dCTP hydroxymethylbilane undecaprenyl- glutamine-- carrier-protein] 5'-triphosphate dGTP 4-methylthiazol-5(2H)- phosphate 7,8- lipoyl-adenylate thiE cofactor) gln synthase III: 3-phosphate phosphorylase: unsaturated sugar [DNA] lysyl- D-alanine HMP-PP synthase: diphosphate tRNA ligase: reductase: 3-hydroxy-2-methylpyridine- ylidene]ethyl phosphate kinase: thiL dihydropteroate thiamine a (7Z)-3-CNY67_RS04875 dehydrogenase: gap CNY67_RS12110 CNY67_RS07270 phosphatase: molybdenum cofactor CNY67_RS13650 CNY67_RS04870 4,5-dicarboxylate precorrin-4 bifunctional lipoyltransferase phosphate an L-glutaminyl- oxotetradec- CNY67_RS06215 guanylyltransferase: Gln a (3R)-3- thiamine thiamine diphosphate and lipoate- thiamine- [tRNA ] sn-glycerol preuroporphyrinogen tetrahydrofolate di-trans,octa-cis CNY67_RS11555 Gln hydroxybutanoyl- 7-enoyl-[acp] an acyl phosphate xanthine 2-phospho-4-(cytidine 5'- (1S,2R)-1- 1-cis- (E)-4-hydroxy-3- a (3R)-3- a [2-oxoglutarate precorrin-4 C(11)- molybdenum cofactor biosynthesis protein ligase: a tRNA 3-phosphate 13-DPG ditrans,octacis- an acyl-[acyl- decaprenyl- carbamoyl a (6S)-5- a ribonucleoside 6,7-dimethyl-8-(1- phosphate synthase/ -undecaprenyl phosphate bis(guanylyl [acp] 3-oxoacyl-[acyl- diphospho)-2-C-methyl-D-erythritol a malonyl-[acp] asp Glu C-(indol-3- vaccenoylglycerol- methylbut-2-en- hydroxyhexacosanoyl- dehydrogenase met methyltransferase: CNY67_RS10310 a peptidoglycan with undecaprenyldiphospho- carrier protein] pyrophosphoryl-(N phosphate formyltetrahydrofolate diphosphate ser D-ribityl)lumazine IMP synthase: thiE dihydrofolate kinase: thiL molybdopterin carrier-protein] 6 cobM phosphate a [lipoyl-carrier 3-hydroxyacyl- 3-hydroxy-2-methylpyridine- (L-alanyl-γ-D-glutamyl- N-acetyl-(N-acetyl-β-D- bifunctional 2-C-methyl- 3-oxoacyl-[acyl- -acetylglucosamine) aspartate ribonucleoside- yl)glycerol riboflavin synthase 3-phosphate1-acyl-sn-glycerol- 1-yl diphosphate4-hydroxy-3- [acp] 3-hydroxyacyl- E2 protein] N synthase: cofactor) reductase: acyl-phosphate bifunctional bifunctional 6 thiamine [acyl-carrier- phosphoglycerate 5-carboxylate L-lysyl-D-alanyl-D- glucosaminyl)muramoyl- D-erythritol 4-phosphate -N-acetylmuramyl- 3-phosphate tryptophan subunit alpha: -dihydrolipoyl- ATP protein]-N - glycerol 3- carrier-protein] peptidoglycan carbamoyltransferase: tetrahydrofolate diphosphate 3-phosphate methylbut-2-en-1- [acyl-carrier- dihydrolipoyl ornithine 5'-nucleotidase precorrin-5 CNY67_RS03760 diphosphate protein] CNY67_RS04870 kinase: pgk alanine) pentapeptide L-alanyl-γ-D-glutamyl-L- cytidylyltransferase/2- (pentapeptide) synthase CNY67_RS04835 L-lysine thiamine phosphate GTP uroporphyrinogen-III NAD biosynthesis from 2- lipoyl-L-lysine a (3R,7Z)-3- phosphate peptidoglycan reductase: glycosyltransferase: CNY67_RS02850 synthase/ reductase, acyltransferase: yl diphosphate protein] dehydrogenase: acetyltransferase/ SurE: 7,8-dihydrofolate Glu dehydratase urate lysyl-D-alanyl-D-alanine C-methyl-D-erythritol ω, mono- subunit cys amino-3-carboxymuconate hydroxytetradec- acyltransferase: glycosyltransferase: CNY67_RS04870 a peptidoglycanCNY67_RS09500 aspartate/ornithine dihydrofolate adenosylcobalamin- 6,7-dimethyl-8- 1,2-dicis- CNY67_RS08030 synthase: dehydratase lpdA N-acetylglutamate CNY67_RS00725 monoglutamate FabZ: fabZ 2,4-cyclodiphosphate trans,octa-cis beta: trpB thiamine- GTP 3',8- NAD biosynthesis semialdehyde 7-enoyl-[acp] plsY CNY67_RS09500 ketoacyl-ACP dimer carbamoyltransferase synthase: dependent: ribityllumazine vaccenoyl- 2-C-methyl-D-CNY67_RS05790 FabZ: fabZ synthase: phosphate octaprenyl diphosphate an L-glutamyl- 3-phospho-D-glycerate 2-(acetamidomethylene) synthase: -decaprenyl CNY67_RS03250 [+ 2 isozymes] synthase: a (2E)-hexacos- dihydrolipoyl inosine cysteine cyclase I (from aspartate) aminocarboxymuconate Glu a (2E)-but- 3-hydroxyacyl- a peptidoglycan with penicillin-binding synthase III: (mycobacteria) Asp/Orn-binding region: CNY67_RS03760 a 2'- D-glyceraldehyde phosphatidate erythritol-2,4- CNY67_RS01760 kinase: thiL a carboxy- biosynthesis [tRNA ] succinate CNY67_RS08355 diphosphate a (6S)-5- trp CNY67_RS04830 2-enoyl-[acp] a [2-oxoglutaratedehydrogenase: N-acetyl-L- precorrin-6A desulfurase MoaA: semialdehyde a tRNA glu 2-enoyl-[acp] [acyl-carrier- a 1-acyl-sn (L-alanyl-γ-D-glutamyl- protein 2: mrdA CNY67_RS04875 CNY67_RS07570 deoxyribonucleoside 3-phosphate cyclodiphosphate adenylated phosphopantothenate biosynthesis I NAD phosphorylation and dephosphorylation 2,3-bisphosphoglycerate- di-trans,octa-cis- 2-C-methyl-D-erythritol- N-carbamoyl- formyltetrahydrofolate dehydrogenaselpdA methionine NifS: nifS moaA asp (2E,6E)-farnesyl crotonyl-[acyl- protein] -glycerol 3- purine ribonucleosides degradation L-lysyl-D-alanyl-D- undecaprenyl diphosphate CMP acyl-carrier protein a 3-oxoacyl-[acp] 5'-diphosphate riboflavin ARP thiamine diphosphate an [L-cysteine [small subunit of IPP independent 2,4-cyclodiphosphate L-aspartate E2 protein] N 6 (8S)-3',8-cyclo-7,8- a 7,8-dihydrofolate diphosphate dehydratase phosphate alanine) pentapeptide L-aspartate + octaprenyl- carrier-protein] desulfurase]-S- molybdopterin dihydroguanosine quinolinate 3-methyl-2-oxobutanoate NAD FabZ: fabZ 1-acyl-sn-glycerol- phosphoglycerate -lipoyl-L-lysine sulfanyl-L-cysteine synthase] oxidase: nadB diphosphate reductase: mutase: CNY67_RS11475 succinate semialdehyde 5'-triphosphate ∆ 3 ∆ 7 3-phosphate adenosine precorrin-6B 2-iminosuccinate nicotinate- 3-methyl-2-oxobutanoate synthase: isoleucine-- CNY67_RS06415 a trans- -cis- - cyclic pyranopterin ile acyltransferase: an inactive lipid II (meso 2251 a (3R)-3- a [pyruvate nucleotide hydroxymethyltransferase: CNY67_RS02620 tRNA ligase: tetradecenoyl-[acp] a ring-opened 7- 1-palmitoylglycerol a formylmethanofuran lysine within a damaged [EntB aryl- guanosine 1-myristoylglycerol acetyl-CoA monophosphate cytochrome pyridine nucleotide all-trans-octaprenyl a butanoyl-[acp] CNY67_RS08030 2-phospho-D-glycerate adenosine deaminase: ribonucleoside a reduced diaminopimelate a palmitoyl-[acp] lipoyl-adenylate coenzyme A hydroxytetracosanoyl- dehydrogenase siroheme biosynthesis diphosphorylase a tetrahydrofolate CNY67_RS12850 ∆ 7 a 1,2-diacyl- SAM methylguanine in DNA gcv protein H DNA pyrimidine in 23S rRNA 3-phosphate GTP dGDP thioredoxin pathway synthase panB diphosphate an L-isoleucyl- cis- - 3-phosphate carrier protein] 6 (carboxylating) d ubiquinol transhydrogenase ATP-NAD/ CNY67_RS04920 triphosphate flavodoxin bifunctional DNA- containing) peptidoglycan 1-acyl-sn-glycerol- formylmethanofuran lipoyltransferase bifunctional DNA- holo-[acyl- 23S rRNA 1-acyl-sn-glycerol- [acp] 3-hydroxyacyl- E2 protein] N acetyl-CoA a thiocarboxylated [tRNA Ile ] tetradecenoyl- sn-glycerol MoaC: moaC oxidase subunit alpha: AcoX kinase: ketoacyl-ACP nicotinate-nicotinamide reductase anaerobic formamidopyrimidine glycosyltransferase: dehydrogenase subunit and lipoate- formamidopyrimidine (guanosine(2251) 3-phosphate adenylate/guanylate -dihydrolipoyl- carboxylase: nucleoside- uroporphyrinogen-III [small subunit of cyclic : nadC 2-dehydropantoate a tRNA Ile [acp]:NAD+ 3-phosphate enolase: CNY67_RS00990 3-phosphate carrier- [acyl-carrier- dihydrolipoyl an oxidized quinolinate subunit CNY67_RS13700 CNY67_RS07285 synthase III: ribonucleoside- glycosylase/ E: CNY67_RS05465 protein ligase: glycosylase/ -2'-O)- acyltransferase: cyclase domain- L-lysine CNY67_RS12115 diphosphate precorrin-7 uroporphyrinogen-III molybdopterin pyranopterin oxidoreductase: phosphatidate nucleotide CNY67_RS09500 acyltransferase: protein] protein] dehydrogenase: thioredoxin NaMN II: cydB CNY67_RS04875 triphosphate DNA-(apurinic or formylmethanofuran CNY67_RS10310 DNA-(apurinic or methyltransferase CNY67_RS08030 containing protein: acetyl-CoA kinase: C-methyltransferase: synthase] phosphate [+ 3 isozymes] CNY67_RS06415 cytidylyltransferase: adenylyltransferase: penicillin- CNY67_RS08030 synthase: 1-myristoyl-2- dehydratase lpdA nicotinate- reductase apyrimidinic site) lyase: dipalmitoyl dehydrogenase subunit a [glycine-cleavage apyrimidinic site) lyase: RlmB: CNY67_RS08270 carboxylase: CNY67_RS09705 cobA guanylyl molybdenum 3-oxoacyl-[acyl- CNY67_RS11790 CNY67_RS12230 binding acyl-carrier protein acpS palmitoleoyl FabZ: fabZ nucleotide nicotinate-nicotinamide cofactor biosynthesis carrier-protein] a (7Z)-tetradec- activating CNY67_RS03415 phosphatidate E: CNY67_RS07635 AMP complex H protein] CNY67_RS03415 a holo-[EntB aryl- CNY67_RS12795 cyclic-GMP a (2E)-tetracos- dihydrolipoyl CNY67_RS12125 dGTP β phosphoenolpyruvate 2,6-diamino-4- protein 6 2-O- phosphatidate siroheme synthase: thioredoxin- diphosphorylase nucleotide -alanine (R)-pantoate leucine-- 7-enoyl-[acp] a CDP- protein: nrdG an active an apurinic site N -lipoyl-L-lysine an apyrimidinic 3',5'-ADP dehydrogenase: NADP + MoO - leu reductase: xanthosine adenosine inosine guanosine a methanofuran carrier protein] 2251 2-enoyl-[acp] a [pyruvate malonyl-CoA 2 diacylglycerol a flavodoxin ribonucleoside hydroxy-5-(N-methyl) lipid II (meso 2:di-trans,octa-cis mrdA methylguanosine precorrin-8x CNY67_RS05845 disulfide (carboxylating) adenylyltransferase: lipoate biosynthesis tRNA ligase: CNY67_RS04870 met 5'-deoxyadenosine within DNA site in DNA dehydrogenaselpdA precorrin-1 : nadC CNY67_RS12230 4-aminobenzoate molybdopterin ketoacyl-ACP semiquinone triphosphate formamidopyrimidine diaminopimelate -undecaprenyl in 23S rRNA reductase: molybdopterin and incorporation I CNY67_RS04820 an L-leucyl- phosphoenolpyruvate E2 protein] N 6 pantoate--beta-alanine biosynthesis cofactor molybdenum cofactor synthase III: reductase precorrin-8X trxB Leu a 3-oxohexanoyl- synthase: CNY67_RS05120 pyruvate kinase: pyk containing) diphosphate uroporphyrinogen-III nicotinate adenine guanylyltransferase: [tRNA ] CNY67_RS04875 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside -lipoyl-L-lysine methylmutase: NaMN ligase: CNY67_RS14980 Leu [acp] thioredoxin- dinucleotide chorismate guanylyl CNY67_RS11555 a tRNA [+ 2 isozymes] CNY67_RS00145 C-methyltransferase: an octanoyl-[acp] 3-oxoacyl-[acyl- phosphorylase: phosphorylase: phosphorylase: phosphorylase: cobA disulfide reductase: nicotinate-nicotinamide NAD synthetase: molybdenum 3-oxoacyl-[acyl- cyclopropane fatty acid CNY67_RS12110 CNY67_RS12110 CNY67_RS12110 CNY67_RS12110 lipoyl(octanoyl) carrier-protein] undecaprenyl- α di-trans,octa-cis a 3-methyl- an apo-[LYS2 L- 1-cis- a (3R)-3- CNY67_RS07855 molybdopterin nucleotide CNY67_RS13695 (R)-pantothenate cofactor carrier-protein] (CFA) biosynthesis pyruvate UDP- -D- [EntF L-seryl- a 3-oxopimeloyl- hydrogenobyrinate a [lipoyl-carriertransferase: lipB reductase: diphospho-N- an acetyl-[acp] a malonyl-[acp] -undecaprenyl branched 2,3,4- acetyl phosphate methylamine 2,3- 2-aminoadipyl- coenzyme A coenzyme A vaccenoylglycerol- asp hydroxyglutaryl- precorrin-2 adenine adenylyltransferase: NAD synthetase: 4-amino-4- reductase: galactose ATP carrier protein] XTP [acp] methyl ester ATP dADP S-adenosyl- protein] N 6 - CNY67_RS04870 a [phospholipid] α acetylmuramoyl- UDP-N-acetyl- ketoacyl-ACP synthase phosphate saturated fattylong-chain acid fatty glycine/sarcosine/ dihydroxybenzoate carrier-protein] 3-phosphate1-acyl-sn-glycerol- [acp] methyl ester hydrogenobyrinate dinucleotide CNY67_RS12230 CNY67_RS14180 pantothenate kinase: deoxychorismate CNY67_RS04870 -D-ribose-1-phosphate undecaprenyl- holo-[acyl- holo-[acyl- XTP/dITP diphosphatase: 3-oxoacyl-[acyl- aspartate 3-hydroxyacyl- L-methionine octanoyl-L-lysine adenosylcobalamin a (9Z)-3- olefinic fatty acid L-alanyl-γ-D- α-D-glucosamine III: CNY67_RS04875 acid--CoA ligase: betaine reductase 2,3- 3-phosphate adenylate/guanylate nucleoside- a,c-diamide synthase: siroheme synthase: a reduced molybdopterin CNY67_RS00985 val a (3R)-3- cyclopropane-fatty- phosphate galactose carrier- carrier- CNY67_RS02735 carrier-protein] aminotransferase: [acyl-carrier- biosynthesis nicotinate adenine + aminodeoxychorismate salvage from cobalamin valine--tRNA ligase: oxohexadec- glutamyl-L-lysyl- undecaprenyldiphospho- dihydroxybenzoate- cyclase domain- diphosphate CNY67_RS00150 CNY67_RS05845 thioredoxin molybdenumtransferase NAD lipoyl hydroxyhexanoyl- acyl-phospholipid 3-oxoacyl-[acyl-carrier- phosphotransferase CNY67_RS08360a 3-methyl- complex protein A: protein] protein] acyltransferase: reductase: CNY67_RS01635 protein] dinucleotide (R)-4'-phosphopantothenate lyase: CNY67_RS00160 synthase: CNY67_RS01730 an L-valyl- 9-enoyl-[acp] Macromolecule Modification D-alanyl-D-alanine muramoylpentapeptide beta-N- CNY67_RS00645 AMP ligase: nucleoside triphosphate containing protein: kinase: met MoeA: CNY67_RS03595 [acp] synthase: ditrans,octacis- protein] reductase: WbaP: branched synthase: synthase: 1-cis-vaccenoyl-CNY67_RS08030 a (3R)-3-CNY67_RS04870 dehydratase hydrogenobyrinate cob(I)alamin [tRNA Val ] 3-oxoacyl-[acyl- acetylglucosaminyltransferase: diphosphate AMP 2,3- CNY67_RS08780 pyrophosphohydrolase: CNY67_RS08270 aspartate/ CNY67_RS09705 sirohydrochlorin NAD synthetase: lipA 3-hydroxyacyl- CNY67_RS03260 undecaprenyldiphospho- CNY67_RS04870 CNY67_RS03670 2,3,4-saturated [+ 2 isozymes] acpS acpS 2-palmitoleoyl hydroxypimeloyl- FabZ: fabZ a,c-diamide methionine molybdopterin NAD synthetase: 4-aminobenzoate a [lipoyl-carrier cob(I)alamin a tRNA Val carrier-protein] a [phospholipid] murG dihydroxybenzoyl a holo-[LYS2 L- a holo-[EntF CNY67_RS11565 cyclic-AMP tyrosine/aromatic a (2E)- CNY67_RS13695 [acyl-carrier- tRNA-uridine 2-thiolation (bacteria) D-ribose 5-phosphate β dATP adenosyltransferase: CNY67_RS13695 6 fatty acid containing N-acetyl-(N-acetyl- -D- an acetoacetyl-[acp] acyl-carrier protein fatty acyl-CoA sarcosine 2-aminoadipyl- 3',5'-ADP 3',5'-ADP L-seryl-carrier phosphatidate [acp] methyl ester aminotransferase: enoylglutaryl- cobalt chelatase: siroheme synthase: molybdenumtransferase protein]-N - adenolsyltransferase: reductase: UDP sugar transferase: adenylate XMP CNY67_RS14985 NAD synthetase: protein] cyclopropane glucosaminyl)muramoyl- carrier-protein] protein] [acp] methyl ester MoeA: CNY67_RS10085 [+ 2 isozymes] lipoyl-L-lysine CNY67_RS03205 CNY67_RS04870 α CNY67_RS00590 CNY67_RS03680 CNY67_RS15240 CNY67_RS05845 SAM MoO - CNY67_RS14180 dehydratase L-alanyl-γ-D-glutamyl-L- -D-galactosyl- 2 adenosylcobalamin a (3R,9Z)-3- UMP oxaloacetate cob(II)yrinate FabZ: fabZ cys diphosphoundecaprenol molybdopterin NAD + hydroxyhexadec- lysyl-D-alanyl-D-alanine siroheme alanine-- a,c-diamide cofactor ala a (2E)-hex- 9-enoyl-[acp] purine deoxyribonucleosides degradation I tRNA ligase: cysteine 2-enoyl-[acp] 3-hydroxyacyl- CNY67_RS13540 long-chain fatty desulfurase ditrans,octacis- a 7,8-dihydro-8- 1-stearoyl- a (7Z,10Z,13Z,16Z a [protein]-L- all trans-decaprenyl- an (11Z)-3- a [lipoyl-carrier a (3R,5Z)-3- an L-alanyl- [acyl-carrier- a peptidoglycan a lipid II a cis- 1-palmitoylglycerol 5 1-palmitoylglycerol a 3-oxoicosanoyl- acid activation NifS: nifS a palmitoyl-[acp] sn-glycerol ,19Z)-3-oxodocosa- glutamate-O 2-methoxy-6- oxooctadec- protein]-N 6 -[(R) hydroxydodec- Ala hexanoyl-[acyl- undecaprenyldiphospho-N- oxoguanine in DNA ITP 3-phosphate dIDP [tRNA ] protein] an [L-cysteine 2'-deoxyadenosine peptidoglycan vaccenoyl-[acp] 3-phosphate -methyl-ester 1,4-benzoquinol [acp] Ala carrier-protein] acetyl-(N-acetylglucosaminyl) bifunctional DNA- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-[acyl- ubiquinone 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- 11-enoyl-[acp]3-oxoacyl-[acyl- -dihydrolipoyl]- 5-enoyl-[acp]3-hydroxyacyl- a tRNA dehydratase a long-chain desulfurase]-S- adenosine deaminase: glycosyltransferase: chemotaxis XTP/dITP diphosphatase: nucleoside- reductase: muramoyl-L-alanyl-γ- formamidopyrimidine 3-phosphate 3-phosphate carrier-protein] biosynthesis 3-phosphate carrier-protein] carrier-protein] L-lysine dihydrolipoyl [acyl-carrier- Amino Acid Biosynthesis FabZ: fabZ fatty acidlong-chain fatty sulfanyl-L-cysteine CNY67_RS04920 CNY67_RS09500 response regulator CNY67_RS02735 diphosphate CNY67_RS06415 D-isoglutaminyl-N-(β- glycosylase/ acyltransferase: acyltransferase: reductase: methyltransferase acyltransferase: reductase: reductase: dehydrogenase: protein] a (2E,9Z)- acid--CoA ligase: protein-glutamate nucleoside triphosphate kinase: nicotinate-nicotinamide D-asparaginyl)-L-lysyl- penicillin-binding DNA-(apurinic or CNY67_RS08030 CNY67_RS08030 CNY67_RS04870 UbiE: CNY67_RS08030 CNY67_RS04870 CNY67_RS04870 lpdA dehydratase superpathway of L- hexadeca-2,9- CNY67_RS08360 peptidoglycan 1-palmitoyl-2- 1-stearoyl- a (3R,7Z,10Z,13Z,16Z methylesterase: pyrophosphohydrolase: 1-palmitoyl-2- a (3R)-3- a (3R,11Z)-3- CNY67_RS09705 L-histidine biosynthesis superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) L-lysine biosynthesis VI β-alanine L-isoleucine a hexanoyl-[acp] dienoyl-[acp] a long-chain nucleotide D-alanyl-D-alanineglycosyltransferase: protein 2: mrdA apyrimidinic site) lyase: CNY67_RS09050 6-methoxy-3-methyl-CNY67_RS02645 cis-vaccenoyl dihydrolipoyl FabZ: fabZ isoleucine biosynthesis I L-tryptophan biosynthesis asparagine-- acyl-carrier protein cis-vaccenoyl 2-palmitoyl- ,19Z)-3-hydroxydocosa- α CNY67_RS11565 hydroxyicosanoyl- hydroxyoctadec- biosynthesis III asn fatty acyl-CoA a [TusA sulfur- adenylyltransferase: di-trans,octa-cis- CNY67_RS03415 acyl-carrier protein a [protein]- - dehydrogenase: a (2E,5Z)-dodeca- dITP biosynthesis IV tRNA ligase: palmitoleoyl- CNY67_RS09500 a peptidoglycan an apurinic site 7,8-dihydro- phosphatidate sn-glycerol 7,10,13,16,19-pentaenoyl-[acp] MeOH 2-all-trans-decaprenyl- phosphatidate [acp] 11-enoyl-[acp] N-acetylglutamyl- 3-oxoacyl-[acyl- carrier protein]- 2'-deoxyinosine CNY67_RS12230 purine-nucleoside 2'-deoxyguanosine undecaprenyl diphosphate L-glutamate IMP a [lipoyl-carrierlpdA 3,5-dienoyl-[acp] oxaloacetate PRPP pyruvate CNY67_RS14605 [acp]:NAD+ penicillin-binding within DNA 8-oxoguanine 3-phosphate 1,4-benzoquinol thr phosphate asp asp propanoate gln an L-asparaginyl- carrier-protein] oxidoreductase: S-sulfanyl- phosphorylase: di-trans,octa-cis- a peptidoglycan protein]-N 6 - aspartate Asn protein 2: mrdA ATP acetolactate aspartate kinase: aspartate 1- long-chain fatty [tRNA ] reductase: CNY67_RS06415 L-cysteine CNY67_RS12110 undecaprenyl diphosphate dimer (E. faeciums) lipoyl-L-lysine aminotransferase: anthranilate tRNA Asn phosphoribosyltransferase: synthase threonine CNY67_RS07155 decarboxylase: acid--CoA ligase: CNY67_RS04870 purine-nucleoside purine-nucleoside CNY67_RS01635 ammonia- synthase: trpD CNY67_RS12690 small subunit: L-aspartyl- CNY67_RS07515 CNY67_RS08360 anthranilate ketoacyl-ACP a palmitoleoyl-[acp] phosphorylase: phosphorylase: aspartate/ lyase, bifunctional N-acetyl-gamma- ditrans,octacis- (R)-4'- 1-cis- 1-stearoyl- 4-(cytidine 5'- a (6Z)-3- a (3R)-3- 1-(5-phospho- CNY67_RS02675 4-phosphate β-alanine propanoyl-CoA synthase III: a [TusD sulfur- CNY67_RS12110 CNY67_RS12110 1-palmitoylglycerol tyrosine/aromatic biosynthetic: ornithine glutamyl-phosphate undecaprenyldiphospho-N- phosphopantothenoyl- MEP CTP a cis- vaccenoylglycerol- a stearoyl-[acp] sn-glycerol SAH a protein diphospho)-2-C- 2-phosphoglycolate a 3-oxoglutaryl- oxooctadec- (R)-NADPHX hydroxyicosanoyl- β-D-ribosyl)-ATP acetolactate anthranilate CNY67_RS04875 carrier protein]- vaccenoyl-[acp] 3-phosphate [acp] methyl ester IDP aminotransferase: ilvA acetyltransferase/ reductase: aspartate- 2-oxoacid:ferredoxin acetyl-(N-acetylglucosaminyl) L-cysteine 3-phosphate 3-phosphate methyl-D-erythritol phosphoglycolate 1-acyl-sn-glycerol- 6-enoyl-[acp] bifunctional [acp] phosphoribosyltransferase: trpD aspartate-- S-sulfanyl- α bifunctional bifunctional 2-C-methyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 5-methylthioadenosine/S- ATP-dependent 4-(cytidine 5'- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-hydroxyacyl- CNY67_RS03680 synthase, N-acetylglutamate CNY67_RS10225 semialdehyde oxidoreductase asp a 3-oxooctanoyl- 2-deoxy- -D-ribose 1-phosphate muramoyl-L-alanyl-γ-D- phosphatase: ADP-dependent nucleoside- (2Z)-2-aminobut- acetylglutamate tRNA ligase: L-cysteine phosphopantothenoylcysteine D-erythritol 4-phosphate 3-phosphate 3-phosphate adenosylhomocysteine Clp protease diphospho)- 3-phosphate carrier-protein] carrier-protein] [acyl-carrier- large subunit, synthase: subunit gamma: [acp] β CNY67_RS07145 NAD(P)H-hydrate diphosphate asp 2-enoate kinase: argB dehydrogenase: N-(5-phosphoribosyl)-anthranilate CNY67_RS00045 an L-aspartyl- palmitoleate thymine degradation isoglutaminyl-N-( -D- decarboxylase/ cytidylyltransferase/2- acyltransferase: acyltransferase: deaminase: proteolytic subunit: 2-C-methyl-D- acyltransferase: reductase: reductase: protein] biosynthetic CNY67_RS01760 N-acetyl-L- CNY67_RS00765 peptidoglycan kinase: 1-(5-phospho-β- N-acetyl-L- CNY67_RS14610 L-alanine asp 3-oxoacyl-[acyl- fatty acid elongation -- saturated asparaginyl)-L-lysyl-D-alanine CNY67_RS08030 CNY67_RS08030 CNY67_RS02515 CNY67_RS10775 erythritol kinase: phosphoglycolate CNY67_RS08030 CNY67_RS04870 CNY67_RS04870 dehydratase/ dehydratase type: ilvB Glu glutamate 5- [tRNA ] glycosyltransferase: phosphopantothenate-- C-methyl-D-erythritol 1,2-dicis- 1-stearoyl-2- 1-palmitoyl-2- a (3R)-3- a (3R,6Z)-3- CNY67_RS09705 N-(5'-phosphoribosyl) asp carrier-protein] thymine S-Inosyl-L- phosphatase: NAD(P)H-hydrate aspartate kinase: D-ribosyl)-AMP glutamate semialdehyde L-aspartate- biosynthesis III 2-oxobutanoate L-alanine tRNA CNY67_RS09500 cysteine ligase CoaBC: coaBC 2,4-cyclodiphosphate acyl-carrier protein vaccenoyl- stearoyl-sn a peptide a peptide 2-phospho-4-(cytidineCNY67_RS06030 palmitoleoyl hydroxyglutaryl- hydroxyoctadec- FabZ: fabZ N-acetylornithine anthranilate isomerase: biosynthesis II reductase: a [TusE sulfur acyl-carrier protein homocysteine CNY67_RS07565 epimerase: a (2E)-icos- ITP CNY67_RS07155 phosphoribosyl- (S)-2-acetolactate semialdehyde 34 pyrimidine deoxyribonucleotides 4'-phosphopantetheine synthase: CNY67_RS08355 phosphatidate -glycerol 3- 5'-diphospho)-2-C- phosphatidate [acp] methyl ester 6-enoyl-[acp] aminotransferase: CNY67_RS04995 CNY67_RS04870 an acetoacetyl-[acp] a uridine carrier protein]-S penicillin-binding 4-(cytidine 5'-diphospho) CNY67_RS07165 2-enoyl-[acp] AMP 2-iminobutanoate 4-hydroxy- cys acetolactate in tRNA dephosphorylation di-trans,octa-cis- a peptidoglycan phosphate methyl-D-erythritol glycolate L-aspartyl- ketol-acid CNY67_RS02355 1-(o-carboxyphenylamino)-1'- pyruvate a (3R)-3- -sulfanylcysteine 5,6-dihydrothymine protein 2: mrdA -2-C-methyl-D-erythritol cyclohydrolase: tetrahydrodipicolinate cysteine synthase nucleoside triphosphate undecaprenyl diphosphate dimer (tetrapeptide) (S)-NADPHX 4-phosphate reductoisomerase: bifunctional deoxyribulose 5'-phosphate alanine hydroxyoctanoyl- hydantoinase/ CNY67_RS12695 synthase: desulfurase small subunit: tyrosine-- tRNA-specific pyrophosphohydrolase: 1-(5-phospho-β-D-ribosyl)- CNY67_RS02670 ornithine indole-3-glycerol transaminase: tyr [acp] oxoprolinase: aspartate- CNY67_RS02455 NifS: nifS CNY67_RS02675 tRNA ligase: 3-hydroxyacyl- 2-thiouridylase: CNY67_RS11565 5-[(5-phosphoribosylamino) (2R)-2,3- gln acetyltransferase/ phosphate synthase: CNY67_RS15120 CNY67_RS01375 dCTP dCMP semialdehyde (2S,4S)-4- ala acetolactate CNY67_RS12640 [acyl-carrier- CNY67_RS11320 ditrans,octacis- a (2R)-2-hydroxy 1-stearoyl- adenosylcobinamide- a cytidine 1402 N-acetyl-D- 1-palmitoylglycerol a (7Z)-3-oxo- an insertion a (3R)-3- methylideneamino]imidazole- dihydroxy-3- 2-oxobutanoate N-acetylglutamate CNY67_RS04990 ala an L-tyrosyl- a CDP- sn-glycerol an acyl-[acyl- α-ribazole a cis-delta21-3- 5-MTR-1-P hydroxy-2,3,4,5- synthase, Tyr undecaprenyldiphospho-N- even numbered sn-glycerol GDP H O diphosphate mannosamine hexadec-7- sequence hydroxypimeloyl- dehydrogenase: methylbutanoate synthase: [tRNA ] protein] a 3-oxoacyl-[acp] 3-(carbamoylamino)- diacylglycerol 3-phosphate carrier protein] 2 ATP H O in 16S rRNA 3-phosphate oxo-C40:1-[acp] 4-carboxamide carbamoyl- 2 N-acetylneuraminate tetrahydrodipicolinate large subunit, (1S,2R)-1-C-(indol-3- Tyr 34 dUTP diphosphatase: acetyl-(N-acetylglucosaminyl) straight chain 2,3,4- CDP-diacylglycerol-- 3-phosphate cobalamin manganese- 16S rRNA 1-acyl-sn-glycerol- enoyl-[acp] element IS30 [acp] methyl ester S-methyl-5- CNY67_RS14610 dihydroxy-acid acetolactate CNY67_RS01760 N-acetyl-L- a tRNA dehydratase a 2-thiouridine 2-methylpropanoate 1-acyl-sn-glycerol- ATPase: 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- transposase: 3-hydroxyacyl- 1-(5-phosphoribosyl) phosphate 4-hydroxy- biosynthetic yl)glycerol 3-phosphate CNY67_RS02360 muramoyl-L-alanyl-γ-D- saturated fattylong-chain acid fatty glycerol-3-phosphate 3- synthase: dependent inorganic (cytosine(1402)-N(4) synthase: 3-phosphate thioribose-1- dehydratase: synthase ornithine FabZ: fabZ in tRNA 3-phosphate CNY67_RS00255 carrier-protein] carrier-protein] CNY67_RS14665 [acyl-carrier- L-aspartate- -5-((5- synthase tetrahydrodipicolinate type: ilvB isoglutaminyl-L-lysyl- acid--CoA ligase: phosphatidyltransferase: CNY67_RS14325 pyrophosphatase: )-methyltransferase CNY67_RS09315 acyltransferase: phosphate ilvD small subunit: tryptophan synthase nucleoside triphosphate peptidoglycan a (R)-2-hydroxy even acyltransferase: reductase: reductase: transposase: protein] semialdehyde phosphoribosylamino) large reductase: a (2E)-oct- (glycyl) -D-alanyl-D-alanine CNY67_RS08360 pgsA [+ 5 isozymes] CNY67_RS05880 [+ 6 isozymes] RsmH: acetylneuraminic CNY67_RS08030 isomerase: CNY67_RS02675 (S)-2-aceto-2- subunit beta: trpB pyrophosphohydrolase: 5 numbered straight 1-(3-sn- CNY67_RS08030a 1-stearoyl 2- 1-palmitoyl- a (3R,7Z)-3-CNY67_RS04870 a cis-delta21-3-CNY67_RS04870 an insertionCNY67_RS08710 dehydratase methylideneamino) 3-methyl-2- subunit: carB 2-enoyl-[acp] 3-oxoacyl-[acyl- glycosyltransferase: diphosphate AMP H + phosphate ADP CNY67_RS06670 acid synthetase: homoserine CNY67_RS06180 (R)-3-amino-2- CNY67_RS11565 + 4 mtnA oxobutanoate acetolactate hydroxybutanoate [+ 2 isozymes] tryptophan- carrier-protein] CNY67_RS09500 chain 2,3,4-saturated phosphatidyl) acyl-carrier protein acyl-sn-glycerol phosphate H an N - 2-myristoyl hydroxy-hexadec- hydroxyC40:1- sequence IS30 a (2E)- FabZ: fabZ 5-(methylthio) dehydrogenase: imidazole-4- Trp a 5-carboxymethylaminomethyl- dUTP dUMP CMP GMP adenosylcobalamin CNY67_RS02745 carbamoyl- dihydrodipicolinate a tRNA octanoyl-[acyl- methylpropanoate methylcytidine 1402 phosphatidate ribulose 1- synthase, 2-aceto-2-hydroxy- -tRNA reductase: 34 penicillin-binding fatty acyl CoA -sn-glycerol 3-phosphate N-acetyl-β- 7-enoyl-[acp] [acp] with integrated enoylpimeloyl- CNY67_RS15125 carboxamide phosphate superpathway of L-methionine reductase: ser indole carrier-protein] ketoacyl-ACP 2-thiouridine in tRNA 2-isopropylmalate branched-chain large subunit, butanoate ligase: trpS CNY67_RS04870 a peptidoglycan di-trans,octa-cisprotein 2: mrdA- 3-phosphate in 16S rRNA neuraminate transposon [acp] methyl ester phosphate isomerase: hisA synthase biosynthesis (by sulfhydrylation) CNY67_RS12015 an L-tryptophanyl- reductase: synthase III: L-homoserine synthase: amino acid biosynthetic isomeroreductase: [tRNA Trp ] 5-hydroxy-CTP 5-hydroxy-CMP dimer (S. aureus) undecaprenyl diphosphate phosphoribulosylformimino- small subunit: tryptophan synthase CNY67_RS06415 CNY67_RS04875 a (3R)-3- CNY67_RS11855 transaminase: type: ilvB (S)-2,3,4,5- L-lysine biosynthesis III CNY67_RS02670 trp a 2,3,4-saturated AICAR-phosphate CNY67_RS06635 oxaloacetate subunit beta: trpB hydroxyacyl-[acyl- a 5-aminomethyl- trp RS07125 trp CNY67_RS01370 tetrahydrodipicolinate (R)-2,3-dihydroxy- fatty acyl-[acp] (S)-2-aceto-2- [+ 2 isozymes] an octanoyl-[acp] 34 carbamoyl 3-hydroxyacyl-carrier protein] 2-thiouridine a cis-delta19- 527 a (3R,5Z)-3- a (3R)-3- a (3R,7Z)-3- (2S)-2- L-ornithine aspartate LL-diaminopimelate 3-methylpentanoate 1-myristoylglycerol a 2,3,4-saturated a 2,3,4-saturated 2- a nucleoside a guanine a cis-delta19-3- a [protein]-L- hydroxybutanoate phosphate asp [acyl-carrier- in tRNA a palmitoyl-[acp] a malonyl-[acp] a palmitoleoyl-[acp] glycine betaine a ribonucleic acid a purine 37-methoxy-38- L-homoserine hydroxy-tetradec- hydroxydocosanoyl- hydroxy-hexadec- imidazole glycerol isopropylmalate aminotransferase: aminotransferase: dihydroxy-acid trp 3-oxoacyl-[acyl- 3-phosphate fatty acyl-[acp] lysophosphatidate triphosphate GTP H O in 16S rRNA oxo-C38:1-[acp] methionine ketol-acid protein] tRNA(5- UTP and CTP dephosphorylation I glycine/sarcosine/ ribonucleoside 2 16S rRNA peptide- O-phospho- phosphate 3-isopropylmalate val CNY67_RS01635 CNY67_RS07215 aspartate kinase: dehydratase: S-methyl-5'-thioadenosine 3-oxoacyl-[acyl-carrier- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- DNA-directed methyl-C57:1-[acp]cyclopropane-fatty- 5-enoyl-[acp]3-oxoacyl-[acyl- 3-oxoacyl-[acyl- [acp] 3-hydroxyacyl- 7-enoyl-[acp]3-hydroxyacyl- reductoisomerase: threonine-- carrier-protein] dehydratase methylaminomethyl- betaine reductase purine-nucleoside GTPase HflX: hflX (guanine(527)-N(7) homoserine O- methionine L-homoserine synthase dehydratase CNY67_RS07155 ilvD thr degradation III protein] reductase: 3-phosphate 3-phosphate RNA polymerase acyl-phospholipid carrier-protein] carrier-protein] [acyl-carrier- [acyl-carrier- CNY67_RS02670 aspartate/ L,L- tRNA ligase: reductase: FabZ: fabZ 2-thiouridylate) UTP complex protein A: phosphorylase: GTPase Era: )-methyltransferase succinyltransferase: (S)-S-oxide subunit HisF: small subunit: leuD L-aspartyl- CNY67_RS04870 acyltransferase: acyltransferase: subunit omega: synthase: reductase: reductase: protein] protein] threonine (R)-2,3-dihydroxy- tyrosine/aromatic diaminopimelate (S)-3-methyl-2- L-selenocysteine biosynthesis I (bacteria) CNY67_RS11950 an L-threonyl- CNY67_RS04870 methyltransferase: S-methyl-5'- CNY67_RS00645 CNY67_RS12110 CNY67_RS12755 RsmG: CNY67_RS07555 reductase: CNY67_RS00510 4-phosphate ketoacyl-ACP synthase CNY67_RS080301-myristoyl-2- CNY67_RS08030 CNY67_RS01280 α-D-ribose- CNY67_RS03260 a (5Z)-3-oxo-CNY67_RS04870 a cis-delta19-3-CNY67_RS04870 dehydratase dehydratase synthase: 3-isopropylmalate 3-methylpentanoate aminotransferase: diaminopimelate oxopentanoate [tRNA Thr ] ketoacyl-ACP CNY67_RS13530 thioadenosine CTP a 2,3,4-saturated a purine base phosphate GDP H + CNY67_RS10505 O-succinyl-L- msrA ornithine 5-methylthioadenosine/S- trimethylamine acetyl phosphate 1-phosphate a cis-methoxy- 7 FabZ: fabZ FabZ: fabZ thrC imidazole glycerol CNY67_RS03680 Thr III: CNY67_RS04875 acyl-carrier protein palmitoleoyl 1,2-diacyl-sn [+ 3 isozymes] an N - tetradec-5- hydroxyC38:1- a (2E,7Z)- a protein-L- dehydratase dihydroxy-acid epimerase: aspartate- branched-chain selenide a tRNA synthase III: 2,3,4- adenosylhomocysteine synthetase: pyrG acyl-carrier protein C59-meroacyl-[acp] homoserine a (2E)-docos- phosphate carbamoyltransferase: tRNA-specific acyl-carrier protein a 3-oxooctadecanoyl-[acp] phosphatidate -glycerol 3- a ribonucleic acid methylguanine 527 enoyl-[acp] [acp] hexadeca-2,7- methionine- large subunit: dehydratase: CNY67_RS07210 semialdehyde amino acid ser a tRNA sec CNY67_RS04875 saturated- a trans-2- deaminase: 2-enoyl-[acp] thr synthase argF a 2,3,4-saturated 2-thiouridylase: UMP phosphate in 16S rRNA dienoyl-[acp] (S)-S-oxide CNY67_RS11850 ilvD asp dehydrogenase: transaminase: selenide, fatty-acid- enoyl-[acyl- CNY67_RS02515 CTP subunit HisH: meso- a 3-oxodecanoyl- fatty acyl-[acp] CNY67_RS11320 S-methyl-5'- 5'-nucleotidase CNY67_RS14610 CNY67_RS01370 water [acp] carrier protein] a 5-methylaminomethyl- threonine CNY67_RS00505 2-isopropylmaleate (S)-3-methyl-2- diaminopimelate serine--tRNA ligase: [acp] thioinosine SurE: aspartate kinase: dikinase reductase: 34 an [amino group carrier a 1-acyl-sn sulfate RS06325 sulfate ammonia- oxopentanoate sulfate L-aspartate- CNY67_RS15085 2-thiouridine 1-cis- an odd numbered a guanine 34 a (9Z)-3-oxo- a (3R,5Z)-3- CNY67_RS07155 diaminopimelate ile SelD: selD ser 3-oxoacyl-[acyl- fabF CNY67_RS00725 a pimeloyl-[acp] ala phytenate queuine a purine 2'- a RNA-DNA hybrid a 3-oxohexacosanoyl- protein]-C-terminal-γ- a cis-delta17-3- -glycerol 3- thr lyase, D-erythro- 3-isopropylmalate branched-chain semialdehyde serine--tRNA ligase: in tRNA a palmitoleoyl-[acp] vaccenoylglycerol- straight chain in tRNA an arachidoyl-[acp] octadec-9- hydroxy-tetradec- decarboxylase: lysA an L-seryl- carrier-protein] CMP long-chain fatty tRNA guanosine(34) deoxyribonucleoside ribonuclease HII: [acp] (L-glutamyl)-L-glutamate oxo-C36:1-[acp] phosphate biosynthetic: AICAR imidazole-glycerol- dehydratase amino acid CNY67_RS15085 an L-seryl- queuosine biosynthesis uridine 8-amino-7-oxononanoate 1-acyl-sn-glycerol-3-phosphate 2,3,4-saturated 3-oxoacyl-[acyl- enoyl-[acp]3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- 5-enoyl-[acp]3-hydroxyacyl- threonine L-aspartyl- 4-hydroxy- superpathway selenophosphate sec reductase: long-chain fatty acid--CoA ligase: purine-nucleoside ketoacyl-ACP small subunit: leuD L-citrulline [tRNA ] ser 5'-nucleotidase synthase: CNY67_RS01805 3-phosphate fatty acid transglycosylase CNY67_RS03465 carrier-protein] acetylglutamate carrier-protein] carrier-protein] 3-phosphate [acyl-carrier- ilvA phosphate transaminase: 4-phosphate tetrahydrodipicolinate of L-threonine [tRNA ] CNY67_RS04870 2,3,4-saturated fatty acid--CoA ligase: phosphorylase: synthase III: ammonia- lys ser 5-MTR-1-P SurE: CNY67_RS08360 Tgt: ribonuclease HI: kinase: argB sulfate RS05675 sulfate imidazoleglycerol- 3-isopropylmalate CNY67_RS01370 a tRNA a (3R)-3- acyl-[acp]:NAD+ preQ 8-amino-7-oxononanoate acyltransferase: an odd numbered α CNY67_RS12110 reductase: reductase: reductase: acyltransferase: protein] lyase, (2Z)-2-aminobut- synthase: biosynthesis 0 CNY67_RS00725 CNY67_RS08360 CNY67_RS01980 2-deoxy- - CNY67_RS04875 phosphate dehydratase argininosuccinate aspartate- APS L-seryl-tRNA(Sec) hydroxydecanoyl- synthase: CNY67_RS05545 CNY67_RS080301-cis-vaccenoyl- straight chain CNY67_RS00195 a (3R)-3-CNY67_RS04870 an [amino group carrier a 3- a (3R,9Z)-3-CNY67_RS04870 a cis-delta17-3-CNY67_RS04870 a 1-acyl-2-CNY67_RS08030 dehydratase biosynthetic: 2-enoate CNY67_RS02455 oxidoreductase: 7-cyano-7- diphosphate AMP diphosphate AMP phytenoyl-CoA D-ribose 1- a purine base a nucleoside 5'- dehydratase: large subunit: ile synthase: semialdehyde (2S,4S)-4- oxaloacetate selenium [acp] cytidine acyl-carrier protein 8-amino-7-oxononanoate acyl-carrier protein 2-palmitoleoyl 2,3,4-saturated a queuosine 34 DNA hydroxyhexacosanoyl- protein]-C-terminal- oxodocosanoyl- hydroxy-octadec- hydroxyC36:1- palmitoyl-sn FabZ: fabZ ilvA adenylyl- aspartate CNY67_RS06415 deazaguanine guanine phosphate monophosphate a (2E,5Z)- CNY67_RS03370 CNY67_RS11850 CNY67_RS06625 dehydrogenase: hydroxy-2,3,4,5- transferase: 3-hydroxyacyl- phosphatidate fatty acyl CoA in tRNA [acp] γ-(5-phospho-L- [acp] 9-enoyl-[acp] [acp] -glycerol 3- 2-oxobutanoate sulfate kinase: aminotransferase: reductase: tetradeca-2,5- L-arginino- CNY67_RS14610 tetrahydrodipicolinate CNY67_RS03755 proline-- [acyl-carrier- Amine and Polyamine Degradation glutamyl)-L-glutamate phosphate imidazole acetol- (2R,3S)-3- CNY67_RS00670 CNY67_RS01635 CNY67_RS00445 dienoyl-[acp] isopropylmalate succinate 4-hydroxy- tRNA ligase: protein] 2-iminobutanoate phosphate L-aspartate- an L- NADPH-dependent Inorganic Nutrient Metabolism argininosuccinate PAPS tetrahydrodipicolinate aspartate/ CNY67_RS14025 dehydratase histidinol- 3-isopropylmalate semialdehyde 7-cyano-7- 4-aminobutanoate a [2-oxoglutarate- 1-stearoyl- an [amino group carrier protein]- a 2'- 1-deoxy-L- 34 a (7Z)-3- a supercoiled a (3R,6Z)-3- tyrosine/aromatic selenocysteinyl- proline-- FabZ: fabZ gondoate biosynthesis choline 1-palmitoylglycerol a 3-oxotetracosanoyl- reduced riboflavin a cytidine a cis-delta15-3- dehydrogenase: L-proline lyase: argH reductase: sec deazaguanine degradation I dehydrogenase a sulfurated decanoate C-terminal-γ-(L-glutamate 5- deoxyribonucleoside [DNA] ARP glycero-tetrulose ethylphosphate phosphate homoserine phosphoadenosine aminotransferase: [tRNA ] pro (anaerobic) sulfate reduction V (dissimilatory, to thiosulfate) SAM a palmitoleoyl-[acp] an oleoyl-[acp] sn-glycerol in tRNA oxohexacos- duplex DNA hydroxyoctadec- CNY67_RS06180 tRNA ligase: degradation III 6 3-phosphate [acp] oxo-C34:1-[acp] transaminase: leuB biosynthesis I L-phenylalanine dehydrogenase: a (2E)-dec- reductase QueF: E2 protein] N - [sulfur carrier] 3-phosphate long-chain fatty semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- 5'-triphosphate DNA polymerase 4-phosphate sulfite reductase: tRNA (cytidine(34) 7-enoyl-[acp] helicase: 6-enoyl-[acp] cytochrome phosphosulfate CNY67_RS03680 CNY67_RS05795 4-aminobutanoate lipoyl 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 6,7-dimethyl-8- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-hydroxyacyl- hisC (2S)-2-isopropyl- biosynthesis I arg CNY67_RS15125 dihydrodipicolinate an L-prolyl- 2-enoyl-[acp] CNY67_RS10985 octanoyl-L-lysine acid--CoA ligase: glutamyl-phosphate III subunit delta': CNY67_RS02590 -2'-O)- CNY67_RS14375 d ubiquinol reductase: asp Pro a malonyl-[acp] an oleoyl-[acp] choline 3-phosphate 3-phosphate ribityllumazine carrier-protein] carrier-protein] carrier-protein] [acyl-carrier- 2-oxobutanoate 3-oxosuccinate reductase: [tRNA ] preQ sulfate synthase: CNY67_RS08360 NADPH-dependent methyltransferase: replicative Glu CNY67_RS05060 decanoyl-[acyl- 1 a [2-oxoglutarate acyltransferase: acyltransferase: reductase: CNY67_RS14570 synthase: reductase: reductase: reductase: protein] oxidase L-histidinol- a tRNA Pro ketoacyl-ACP choline lipA chorismate L-homoserine CNY67_RS12015 CNY67_RS10225 FMN reductase: CNY67_RS01380 DNA helicase: subunit sulfite RS01390 sulfite acetolactate phosphate glutamate 5- carrier-protein] synthase III: tRNA guanosine(34) succinate trimethylamine- an unsulfurated dehydrogenase CNY67_RS080301-palmitoyl-2- CNY67_RS080301-stearoyl-2- diphosphate AMP decanoyl-CoA an [amino group carrier protein]- [+ 7 isozymes] CNY67_RS04830 a (3R)-3-CNY67_RS04870 a 2'-O- a (3R,7Z)-3-CNY67_RS04870 a cis-delta15-3-CNY67_RS04870 dehydratase chorismate mutase: sulfite aspartate kinase: 5'-deoxyadenosine met 6 6,7-dimethyl-8-(1- CNY67_RS03800 34 CNY67_RS02005 synthase kinase: proB (S)-2,3,4,5- reductase: an (11Z)-3-CNY67_RS04875 semialdehyde lyase: cutC [sulfur carrier] E2 protein] N acyl-carrier protein palmitoleoyl acyl-carrier protein oleoyl-sn-glycerol C-terminal-γ-(5-phospho- [DNA] hydroxytetracosanoyl- methylcytidine hydroxyhexacos- hydroxyC34:1- a (2E,6Z)-FabZ: fabZ II: cydB histidinol- γ CNY67_RS12555 CNY67_RS07155 transglycosylase D-ribityl)lumazine a single -L-glutamyl tetrahydrodipicolinate CNY67_RS06415 oxo-icos-11- trimethylamine -lipoyl-L-lysine L-glutamyl)-L-glutamate riboflavin in tRNA ethanol small subunit: phosphatase: 4-methyl-2- Tgt: NAD-dependent phosphatidate 3-phosphate [acp] 7-enoyl-[acp] [acp] stranded DNA octadecadienoyl- 5-phosphate prephenate enoyl-[acp] CNY67_RS02675 CNY67_RS02205 oxopentanoate L-aspartyl- phenylalanine- CNY67_RS01980 APS succinate- [acp] gamma-glutamyl- a decanoyl-[acp] 3-oxoacyl-[acyl- a 7-aminomethyl-7- acetolactate histidinol branched-chain prephenate superpathway of L- O-acetyl-L- 4-phosphate -tRNA ligase semialdehyde phosphate carrier-protein] deazaguanosine 34 adenylyl-sulfate reductase synthase, amino acid dehydratase: asparagine biosynthesis homoserine hydrogen sulfide α ε subunit alpha: dehydrogenase: a [pyruvate a 2-methyl cyclic 1402 a (5Z)-3- a (3R,9Z)-3- phosphate L- -amino- - aspartate- 3-oxoacyl-[acyl- reductase: subunit beta: aprB 5'-deoxy-5'- a cytidine + a phosphate large subunit, transaminase: reductase: CNY67_RS12555 CNY67_RS11970 in tRNA gabD dehydrogenase a sulfurated branched 2,3,4- linoleate a purine dehypoxanthine NAD NADPH acetyl phosphate oxotetracos- a cis-delta13-3- hydroxy-octadec- phosphatase: CNY67_RS12225 keto-pimelate semialdehyde carrier-protein] CNY67_RS04870 tRNA preQ1(34) S- adenylylsulfate reductase SAM dGTP arsenate fluoroadenosine in 16S rRNA oxo-C32:1-[acp] FMN ATP monoester biosynthetic CNY67_RS01370 keto- E2 protein] N 6 - [sulfur carrier] saturated fatty acid long-chain fatty ribonucleoside futalosine purine-nucleoside 16S rRNA pyridine nucleotide 5-enoyl-[acp] 9-enoyl-[acp] CNY67_RS12730 asp O-acetylhomoserine diaminopimelate dehydrogenase: phenylalanine- reductase: a (3R,11Z)-3- adenosylmethionine subunit alpha: aprA succinate lipoyl deoxyguanosinetriphosphate long-chain fatty purine-nucleoside 1,4-dihydroxy- glycine reductase: 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-hydroxyacyl- cytochrome type: ilvB L-glutamate-5- phenylpyruvate -tRNA ligase hydroxy-icos- octanoyl-L-lysine acid--CoA ligase: acid--CoA ligase: phosphorylase: (cytidine(1402)-2'-O) transhydrogenase bifunctional d ubiquinol aminocarboxypropyltransferase/ dehydrogenase: CNY67_RS14610 phe CNY67_RS04870 ribosyltransferase- synthase: triphosphohydrolase: phosphorylase: 6-naphthoate CNY67_RS00630 carrier-protein] carrier-protein] [acyl-carrier- (S)-2-aceto-2- histidinol leu semialdehyde aspartate/ subunit beta: 11-enoyl-[acp] sulfite CNY67_RS08360 CNY67_RS08360 CNY67_RS12110 -methyltransferase: subunit alpha: reductase: reductase: riboflavin kinase/ protein] oxidase cysteine synthase: CNY67_RS07015 L-aspartate- ketoacyl-ACP isomerase QueA: Alcohol Degradation lipA a [pyruvate CNY67_RS00660 a 2-methyl CNY67_RS12110 synthase: 5-fluoro-5- [+ 2 isozymes] predicted hydroxybutanoate tyrosine/aromatic asparagine asparagine CNY67_RS11980 3-hydroxyacyl- rsmI CNY67_RS13700 CNY67_RS04870 CNY67_RS04870 FAD synthetase: dehydratase subunit histidinol CNY67_RS06365 meso- semialdehyde an L-phenylalanyl- synthase III: CNY67_RS00785 an unsulfurated 5'-deoxyadenosine met dehydrogenase 2'-deoxyguanosine PPP branched AMP diphosphate linoleoyl-CoA ribose-1-arsenate a purine base CNY67_RS07315 deoxy-D-ribose adenine a 2'-O- a (3R,5Z)-3- a cis-delta13-3- ABC Phe 6 i AMP diphosphate an unknown 1,4-dihydroxy- 1402 [+ 3 isozymes] CNY67_RS12710 2+ 2+ ketol-acid aminotransferase: synthase synthase [tRNA ] [acyl-carrier- [sulfur carrier] E2 protein] N methylcytidine gly FabZ: fabZ II: cydB 2+ 2+ Ni Ni dehydrogenase: O-acetylhomoserine diaminopimelate CNY67_RS04875 34 dissimilatory-type dissimilatory-type 2,3,4-saturated 1-phosphate hydroxytetracos- hydroxyC32:1- FAD a (2E,9Z)- Cd CadA Cd transporter reductoisomerase: CNY67_RS03680 (glutamine- (glutamine- L-cysteine homoserine Phe protein] an epoxyqueuosine glycerol degradation I compound 6-naphthoate NADP + NADH hisD aminocarboxypropyltransferase/ a tRNA a 3- sulfite reductase sulfite reductase -lipoyl-L-lysine fatty acyl-CoA in 16S rRNA 5-enoyl-[acp] [acp] octadeca-2,9- an alcohol of Ni2+ CNY67_RS02670 (S)-1-pyrroline- hydrolyzing) hydrolyzing) biosynthesis I dehydrogenase: dehydratase in tRNA cysteine synthase: diaminopimelate oxododecanoyl- subunit alpha: dsrA subunit alpha: dsrA urea cycle dienoyl-[acp] histidinal 5-carboxylate phe : asnB : asnB CNY67_RS15125 FabZ: fabZ (R)-2,3-dihydroxy- glycine CNY67_RS09360 decarboxylase: lysA [acp] glycerol pyrroline-5- [+ 3 isozymes] [+ 3 isozymes] glycerol lactate RS01235 lactate 3-methylpentanoate biosynthesis III ser 3-oxoacyl-[acyl- a (2E,11Z)-icosa- Ca 2+ RecA Ca 2+ histidinol L-homoserine ammonium undecaprenyl-diphospho-N α ω a 1-alkyl-sn a (5Z)-3- a (3R,11Z)-3- (3R,5S)-3- carboxylate serine carrier-protein] 34 kinase: , -9Z- 5'-chloro-5'- 1-[18-hydroxyoleyl]- dihydroxy-acid dehydrogenase: lys methionine-- 2,11-dienoyl-[acp] a queuosine -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine 16-hydroxypalmitate 1-myristoylglycerol oleate futalosine roseoflavin met -glycerol 3- a cis-delta11-3- glyoxylate reductase: asn asn acetyltransferase: met reductase: trithionate thiosulfate glpK a myristoyl-[acp] octadecenedioate deoxyadenosine 2-lyso-phosphatidate ATP oxododec- hydroxyoctadec- hydroxy-1- dehydratase: hisD L-homocysteine tRNA ligase: in tRNA carbamoyl- D-glutamyl-L-lysyl- D-alanine long-chain fatty 3-phosphate long-chain fatty long-chain fatty futalosine purine-nucleoside 1-acyl-sn-glycerol- 5'-phosphate phosphate oxo-C30:1-[acp] alanine--glyoxylate proC CNY67_RS13600 an L-methionyl- CNY67_RS04870 (2E,11Z)-icosa- arg sn-glycerol undecaprenyldiphospho- 1-acyl-sn-glycerol- aspartate/ 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- 5-enoyl-[acp]3-oxoacyl-[acyl- 11-enoyl-[acp]3-hydroxyacyl- pyrroline-5- ilvD L-glutamate CNY67_RS06200 phosphate acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: hydrolase: phosphorylase: 3-phosphate bifunctional aminotransferase L-glutamine biosynthesis I O-acetyl-L-serine [elongator a (3R)-3- 2,11-dienoyl- 3-phosphate muramoylpentapeptide beta-N- 3-phosphate tyrosine/aromatic 3-phosphate carrier-protein] carrier-protein] [acyl-carrier- carboxylatepyrroline-5- a cation RS07845 a cation (S)-3-methyl-2- his biosynthesis III synthase CNY67_RS08360 CNY67_RS08360 CNY67_RS08360 mqnB CNY67_RS12110 acyltransferase: riboflavin kinase/ citrate RS08480 citrate pro elongator Met hydroxydodecanoyl- [acp] reductase: acetylglucosaminyltransferase: acyltransferase: acyltransferase: reductase: reductase: protein] carboxylate family protein: O-phospho- glycine biosynthesis I tRNA ] large anaerobic ω-carboxy- 5-chloro-5- aminotransferase: oxopentanoate Met CNY67_RS06415 CNY67_RS08030 FAD synthetase: reductase: CNY67_RS11050 cysteine tRNA [acp] argininosuccinate subunit: carB glycerol-3- ditrans,octacis-undecaprenyldiphospho-murG 16-hydroxypalmitoyl- CNY67_RS08030 dehypoxanthine 1-[18-hydroxyoeoyl]-2- CNY67_RS03680 a 2-acyl-1-alkyl-CNY67_RS08030 a cis-delta11-3-CNY67_RS04870 a (3R,5Z)-3-CNY67_RS04870 dehydratase branched-chain Glu 2-oxoglutarate L-homoserine 3-hydroxyacyl- lipoprotein posttranslational thiosulfate AMP diphosphate dimyristoyl AMP diphosphate (9Z)-octadec- diphosphate AMP oleoyl-CoA hypoxanthine adenine deoxyribose CNY67_RS12710 4-(methylsulfanyl) proC gly synthase A: cysK NADP-specific lyase: argH phosphate UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- CoA acyl-carrier protein futalosine [18-hydroxy-lioleoyl]-sn roseoflavin adenine sn-glycerol hydroxyC30:1- hydroxydodec- a (2E,11Z)-FabZ: fabZ trans-4-hydroxy- amino acid glutamine synthetase: threonine [acyl-carrier- a gondoyl-[acp] modification carbamoyl- phosphatidate 9-enoyl-CoA 1-phosphate -2-oxobutanoate chloride RS12475 chloride [+ 2 isozymes] glutamate ser dehydrogenase L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine -glycerol 3-phosphate dinucleotide 3-phosphate [acp] 5-enoyl-[acp] octadeca-2,11- L-proline citrate RS05340 citrate transaminase: CNY67_RS04975 synthase: protein] a [prolipoprotein]- phosphate dehydrogenase: serine subunit A: glpA dienoyl-[acp] CNY67_RS01370 glutamine synthetase cys thrC lysine- dehydratase L-cysteine L-arginino- synthase CNY67_RS08125 hydroxymethyltransferase: glyA a tRNA Lys L-ornithine small subunit: anaerobic glycerol- type III: CNY67_RS07200 -tRNA FabZ: fabZ prolipoprotein succinate ile gln Glu thr gly CNY67_RS06635 3-phosphate a 2-oxo a cis-delta21-39- 1498 a (9Z)-3- ligase: lysS a nucleoside a double 3-oxo- a uracil a nucleoside 2+ 2+ fluoride RS07075 fluoride an L-lysyl- a (2E)-dodec- diacylglyceryl dehydrogenase 18-hydroxystearate 1-palmitoylglycerol octanoate isobutanal hydantoin an oxidized Mo RS14210 Mo Lys carboxylate a myristoyl-[acp] stranded DNA docosapentaenoyl-CoA oxo-40-methyl- in 16S rRNA oxooctacos- ala [tRNA ] 2-enoyl-[acp] transferase: carbamoyl 3-phosphate triphosphate cytochrome c diphosphate subunit C: 2-oxoacid:ferredoxin long-chain fatty long-chain fatty acetaldehyde ATP-dependent 3-oxoacyl-[acyl- C59:1-[acp] hydantoinase/ 16S rRNA 3 9-enoyl-[acp] nucleoside- lys CNY67_RS11890 ornithine phosphate 1-acyl-sn-glycerol- nucleoside triphosphate cyclopropane-fatty- periplasmic [NiFe] 3-oxoacyl-[acyl- alanine dodecanoyl-[acyl- argininosuccinate CNY67_RS05380 oxidoreductase acid--CoA ligase: acid--CoA ligase: dehydrogenase RecD-like carrier-protein] oxoprolinase: (uracil(1498)-N(3))- diphosphate a [prolipoprotein]- carbamoyltransferase: 3-phosphate pyrophosphohydrolase: acyl-phospholipid hydrogenase carrier-protein] racemase: carrier-protein] (S-diacylglyceryl) synthase: subunit gamma: CNY67_RS08360 acyltransferase: CNY67_RS08360 (acetylating): DNA helicase: reductase: synthase: CNY67_RS01375 methyltransferase: small subunit: reductase: kinase: Na + RS07130 Na + argF DHAP CNY67_RS11565 alr Mo 2+ RS11395 Mo 2+ reductase: CNY67_RS00765 CNY67_RS08920 CNY67_RS14995 CNY67_RS04870 3 CNY67_RS08020 CNY67_RS09705 Metabolic Regulator -L-cysteine CNY67_RS06625 a reduced 18-hydroxystearoyl- CNY67_RS080301-palmitoyl- a nucleoside 5'- (5Z,8Z,11Z,14Z,17Z) CNY67_RS03260 an N - CNY67_RS06355 a cis-delta9-3-CNY67_RS04870 Carbohydrate Biosynthesis AMP diphosphate diphosphate AMP octanoyl-CoA + N-carbamoylglycine a nucleoside CNY67_RS06415 L-citrulline H + ferredoxin [iron- CO an acyl-CoA CoA H NADH isobutanoyl-CoA a 5'-phosphooligonucleotide -3R-hydroxy- a cis-keto-C60- methyluracil 1498 a reduced D-ala Biosynthesis histidine-- 2 acyl-carrier protein 2-myristoyl monophosphate hydroxyC28:1- his signal meroacyl-[acp] cytochrome c triphosphate tRNA ligase: sulfur] cluster phosphatidate docosapentaenoyl-CoA in 16S rRNA 3 [acp] gluconeogenesis I a dodecanoyl-[acp] peptidase nitrate RS02415 nitrate O-antigen building blocks biosynthesis (E. coli) PRPP biosynthesis I ppGpp biosynthesis CNY67_RS00040 ADP-L-glycero-β- an L-histidyl- II: lspA sulfoacetaldehyde degradation I His 6-phospho a 1-acyl-sn D-manno-heptose UDP-α-D- α-D- [tRNA ] decaprenyl-diphospho-N- UDP-N-acetyl- (15Z)- an L-phenylalanyl- an N-terminal an (R)-2- an (S)-2- (indol-3- a 3- an aromatic (S)-malate D-glucopyranose D-ribose 5- pppGpp a tRNA His 3-oxoacyl-[acyl- acetylmuramoyl-pentapeptide α-D-glucosamine D-glucono- coenzyme A acyl-carrier protein oxodocosanoyl- (S)-dihydroorotate a stearoyl-[acp] MEP -glycerol 3- histidinol biosynthesis galactose glucopyranose an (S-diacyl- a lipoprotein tetracosenoate [tRNA Phe ] arginyl-[protein] halocarboxylate halocarboxylate yl)pyruvate amino acid 6-phosphate phosphate sulfoacetaldehyde sulfite oxidation III undecaprenyldiphospho- long-chain fatty HAD family 1,5-lactone HAD family indolepyruvate phosphate D-sedoheptulose 1-phosphate glucose-6- ribose-phosphate bifunctional (p)ppGpp carrier-protein] sn-glyceryl) signal peptide leucyl/phenylalanyl- [acp] 3-oxoacyl-[acyl- 1-deoxy-D-xylulose- 1-acyl-sn-glycerol- aspartate/ histidinol glucose-1-phosphate muramoylpentapeptide beta-N- acid--CoA ligase: hydrolase: hydrolase: ferredoxin ACP S- dihydroorotase: ketoacyl-ACP malate 7-phosphate phosphate pyrophosphokinase: synthetase/guanosine- reductase: -L-cysteinyl- tRNA--protein 6-phosphogluconolactonase: carrier-protein] 5-phosphate 3-phosphate tyrosine/aromatic dehydrogenase: NAD-dependent D-sedoheptulose UDP-Galf thymidylyltransferase: guanosine 3'- laurate sulfite acetylglucosaminyltransferase: CNY67_RS08360 CNY67_RS01885 CNY67_RS01885 oxidoreductase: malonyltransferase: CNY67_RS02855 synthase III: dehydrogenase, isomerase: CNY67_RS06020 3',5'-bis(diphosphate) 3'- CNY67_RS04870 [apolipoprotein] sulfoacetaldehyde transferase: pgl reductase: reductoisomerase: acyltransferase: aminotransferase: hisD malic enzyme 4: 7-phosphate rfbA diphosphate 5'- adenylyl-sulfate murG CNY67_RS12210 CNY67_RS10510 CNY67_RS04875 IMP NAD-requiring: dTDP-α-D-glucose CNY67_RS09965 PRPP pyrophosphohydrolase: glycine--tRNA ketoacyl-ACP long-chain fatty acetyltransferase: xsc decaprenyl-pyrophosphoryl- (Z)-15- CNY67_RS06160 [+ 2 isozymes] D-gluconate [+ 2 isozymes] a (3R)-3-CNY67_RS04870 N-carbamoyl- 1-deoxy-D-CNY67_RS11795 a 1,2-diacyl-CNY67_RS08030 CNY67_RS03680 CNY67_RS05305 isomerase: triphosphate 3'- reductase AMP diphosphate L-phenylalanyl-L- an (S)-2- an (R)-2- S-2-(indol-3 a 3-oxoicosanoyl- an aromatic his dehydrogenase: CNY67_RS05305 F6P ligase subunit beta: synthase III: acid--CoA ligase: tetracosenoyl-CoA Phe a halide anion a halide anion a malonyl-[acp] sn-glycerol D-glycero-D-CNY67_RS12950 dTDP- CNY67_RS05295 diphosphatase: UDP (N-acetylglucosamine)-N- a tRNA hydroxycarboxylate 6-phosphate hydroxyacid yl)acetyl-CoA hydroxydocosanoyl- L-aspartate [acp] xylulose 5- CNY67_RS03390 CNY67_RS09595 CNY67_RS04875 CNY67_RS08360 a peptide subunit beta: aprB arginyl-[protein] 3-phosphate 2-oxo-acid manno-heptose glucose 4,6- glutamine-- CNY67_RS05295 an N-acyl-(S- acetyl phosphate sulfite acetylmuramyl-(pentapeptide) [acp] phosphate glycine- diacyl-sn-glyceryl) adenylylsulfate pyruvate 7-phosphate dehydratase: fructose-6- lauroyl-CoA reductase subunit heptose 7- rfbB phosphate -tRNA a 3-oxotetradecanoyl- -L-cysteinyl- phosphate a 3- alpha: aprA an L-phenylalanyl- an N-terminal an (S)-2- an (R)-2- a [protein]-L- D-galactopyranose phosphate transaminase GTP ppGpp ligase [acp] [lipoprotein] acetyltransferase: CAIR asp 18-hydroxyoleate a protein F6P a myristoyl-[acp] oxodocosanoyl- an octanoyl-[acp] a hexanoyl-[acp] phosphoenol dTDP-4-dehydro- APS [tRNA Phe ] halocarboxylate halocarboxylate proline (ω = 180) IMP dGDP 6-phosphate oxaloacetate phosphoenolpyruvate kinase: rfaE2 subunit CNY67_RS13495 long-chain fatty L-lysyl-[protein] HAD family HAD family diphosphate--fructose- peptidyl-prolyl cis- pyruvate ribose 5- β 6-deoxy-α-D- (isomerizing) gly 3-oxoacyl-[acyl- phosphoribosylaminoimidazolesuccinocarboxamide leucyl/phenylalanyl- HyaD/HybD family [acp] 3-oxoacyl-[acyl- synthase: D-glycero- -D- alpha: acid--CoA ligase: hydrolase: hydrolase: 6-phosphate 1- ketoacyl-ACP trans isomerase: ketoacyl-ACP ketoacyl-ACP phosphate glucopyranose : glmS carrier-protein] phosphate synthase: CNY67_RS06425 tRNA--protein hydrogenase maturation carrier-protein] pyruvate CNY67_RS05120 manno-heptose nucleoside- bifunctional (p)ppGpp glyQ CNY67_RS08360 CNY67_RS01885 CNY67_RS01885 phosphotransferase: synthase III: CNY67_RS15430 synthase III: synthase III: IMP cyclohydrolase: isomerase D-glucosamine Gly reductase: acetyltransferase transferase: endopeptidase: hybD kinase: pyk [+ 2 isozymes] 1,7-bisphosphate dTDP-4- diphosphate synthetase/guanosine- a glycyl-[tRNA ] tRNA processing phosphoribosylaminoimidazolesuccinocarboxamide CNY67_RS04875 reductase: CNY67_RS04875 CNY67_RS04875 6-phosphate CNY67_RS04870 stearate biosynthesis PlsX: CNY67_RS04880 pyruvate fermentation Carboxylate Degradation CNY67_RS06160 [+ 2 isozymes] [+ 2 isozymes] CNY67_RS06185 [+ 4 isozymes] CNY67_RS09780 B: rpiB D-glycero-beta-D- dehydrorhamnose kinase: Gly synthase: CNY67_RS13400 18-hydroxyoleoyl- a peptide a peptide β a (3R)-3-CNY67_RS04870 3',5'-bis(diphosphate) 3'- bifunctional (p)ppGpp a tRNA a (3R)-3- sulfate to acetate IV AMP diphosphate L-phenylalanyl- an (S)-2- an (R)-2- -D-fructose 1,6- a 3-oxohexadecanoyl- a [protein]-L- a 3-oxodecanoyl- a 3-oxooctanoyl- dGTP pyruvate D-tagatofuranose manno-heptose- 3,5-epimerase: phosphoglucosamine CNY67_RS09705 II (bacteria and plants) CoA a tRNA Phe a halide anion a halide anion hydroxydocosanoyl- ω FAICAR phosphoenol pyrophosphohydrolase: synthetase/guanosine- hydroxytetradecanoyl- a polycistronic acetyl-CoA SAICAR L-lysyl-[protein] hydroxycarboxylate hydroxyacid bisphosphate [acp] proline ( = 0) [acp] [acp] 6-phosphate 1,7-bisphosphate CNY67_RS09805 mutase: [acp] pyruvate CNY67_RS05295 3',5'-bis(diphosphate) 3'- [acp] tRNA precursor pyruvate 7-phosphatase: dTDP-4- CNY67_RS04175 a palmitoyl-[acp] enolase: pyrophosphohydrolase: 3-hydroxyacyl- CNY67_RS03230 dehydrorhamnose D-glucosamine CNY67_RS05295 ketoacyl-ACP CNY67_RS00990 D-glycero-β-D- methionine-- [acyl-carrier- ribonuclease E: 2-amino-6-[1-hydroxyethyl]- a 23S rRNA a double- an organic a [protein]-L- D-ribulose 3,5-epimerase: rfbC 1-phosphate GDP met synthase III: glycyl radical 7-hydroxylaurate a (3Z)-dec- 2,3- roseoflavin manno-heptose tRNA ligase: protein] CNY67_RS10275 ribonuclease E: Carbohydrate Degradation superpathway of acetate pimeloyl-CoA ala 7-methyl-7,8-dihydropterin an acyl-carrier protein coenzyme A a malonyl-[acp] uridine 1911/1915/1917 a lignoceroyl-[acp] helix DNA hydroperoxide β-isoaspartate a malonyl-[acp] phosphoenol dADP 5-phosphate 2-phospho- dTDP-4-dehydro- UDP-N- CNY67_RS04875 CNY67_RS10275 protein: long-chain fatty 3-enoyl-[acp] 23S rRNA diaminopropanoate DNA helicase UvrD: lipid hydroperoxide protein-L- bifunctional pyruvate ribulose- 1-phosphate CNY67_RS06200 an L-methionyl- dehydratase a 3-oxooctadecanoyl- utilization and formation 8-amino-7-oxononanoate 2-amino-4-hydroxy-6- holo-[acyl- ketoacyl-ACP D-glycerate β-L-rhamnose acetylglucosamine CNY67_RS06110 acid--CoA ligase: pseudouridine(1911/ ketoacyl-ACP CNY67_RS14385 peroxidase: isoaspartate O- ketoacyl-ACP riboflavin kinase/ phosphate 3- Met FabZ: fabZ [acp] a tRNA precursor D-mannose degradation synthase: CNY67_RS01805 hydroxymethyldihydropteridine carrier-protein] synthase III: diaminopropionate pyruvate 2,3-bisphosphoglycerate- D-glycero-beta-D- dTDP-4- diphosphorylase/ Amine and Polyamine Biosynthesis [initiator tRNA ] synthase III: synthase III: FAD synthetase: Met with a 5' extension exoribonuclease: rnr a tRNA precursor with acetate diphosphokinase: folK CNY67_RS08360 synthase: acpS CNY67_RS04875 1915/1917) synthase: ammonia-lyase: dpaL DNA helicase UvrD: CNY67_RS07715 methyltransferase: kinase: pyk epimerase: independent manno-heptose dehydrorhamnose Cell Structure Biosynthesis initiator tRNA a (2E)-tetradec- 3-oxoacyl-[acyl- acetate--CoA 8-amino-7-oxononanoate a (5Z)-3- CNY67_RS04875 CNY67_RS04875 glucosamine-1- and a long 3' trailer a 5' extension and D-mannopyranose acetyl-CoA formate [1-(2-amino-7-methyl-4-oxo- CNY67_RS04935 CNY67_RS07500 [+ 2 isozymes] βCNY67_RS07910 CNY67_RS12710 rpe carrier-protein] 7-hydroxylauroyl- acyl-carrier protein 3',5'-ADP acyl-carrier protein oxododec- 1911/ an unwound a protein L- - a 3- phosphoglycerate 1-phosphate reductase: rfbD phosphate N- 2-enoyl-[acp] ligase: acs synthase: CNY67_RS05545 7,8-dihydro-3H-pteridin- AMP diphosphate a pseudouridine a 3-oxohexacosanoyl- roseoflavin dATP pyruvate D-xylulose Secondary Metabolite Biosynthesis putrescine reductase: a short 3' extension 6-phosphate acetate kinase: CoA 5-enoyl-[acp] pyruvate double- an alcohol isoaspartate oxodocosanoyl- mutase: adenylyltransferase: dTDP-β-L- acetyltransferase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) myristoyl-[acyl- RNase BN mannose-1-phosphate phosphate 8-amino-7-oxononanoate coenzyme A 6-yl)]ethyl diphosphate 1915/1917 in 23S rRNA [acp] 5'-phosphate 5-phosphate biosynthesis I CNY67_RS04870 ribonuclease CNY67_RS13500 stranded DNA α-methyl ester [acp] CNY67_RS11475 rfaE2 rhamnose glmU carrier-protein] ribonuclease: guanylyltransferase/ acetyltransferase: preQ biosynthesis UDP-N-acetyl- a (3R)-3- P protein 3-phospho- D-glycero-beta-D- N-acetyl-α-D- 0 spermine biosynthesis reductase: rnr mannose-6- CNY67_RS13495 myo-inositol arg α-D-glucosamine hydroxyoctadecanoyl- component: acetyl phosphate acetyl-CoA D-glycerate manno-heptose glucosamine CNY67_RS06415 rnpA phosphate isomerase: 6-(hydroxymethyl) a very-long- a (6S)-5- a [lipoyl-carrier 3-[(1- a [protein]- D-ribose 5- biosynthesis biosynthetic UDP-N-acetylglucosamine [acp] phosphate NaMN 5,6-dimethylbenzimidazole a (7Z)-hexadec- (R)-lipoate DNA with lesion (S)-malate NMN 1-phosphate 1-phosphate CNY67_RS13005 -7,8-dihydropterin chain fatty acid formyltetrahydrofolate a malonyl-[acp] protein]-L-lysine SAM carboxyvinyl) a dodecanoyl-[acp] a behenoyl-[acp] a butanoyl-[acp] L-histidine phosphate phosphoglycerate GTP D-glucopyranose arginine SAM 1-carboxyvinyltransferase: 3-hydroxyacyl- a tRNA precursor a tRNA precursor with acetyltransferase 7-enoyl-[acp] adenylyltransferase: a myristoyl-[acp] F6P nicotinate-nucleotide-- 2-amino-4-hydroxy-6- long-chain fatty 5-formyltetrahydrofolate ketoacyl-ACP lipoyltransferase oxy]benzoateaminofutalosine excinuclease fumarate hydratase: 5'-nucleotidase histidine kinase: ribose 5- kinase: pgk UDP-N- 6-phosphate decarboxylase: murA [acyl-carrier- with a 5' extension a short 3' extension PlsX: ketoacyl-ACP ketoacyl-ACP ketoacyl-ACP rfaE2 acetylglucosamine GTP protein] CNY67_RS04880 dimethylbenzimidazole hydroxymethyldihydropteridine acid--CoA ligase: cyclo-ligase: synthase III: and lipoate- synthase MqnE: ABC subunit UvrB: CNY67_RS05330 SurE: CNY67_RS00455 phosphate β cyclohydrolase CNY67_RS09670 UDP-N-acetyl-α- 3-oxoacyl-[acyl- phosphate phosphoribosyltransferase: CNY67_RS08360 protein ligase: synthase III: synthase III: CNY67_RS06170 synthase III: fumarate hydratase: isomerase 13-DPG ADP-D-glycero- - diphosphorylase/ agmatine dehydratase diphosphokinase: folK CNY67_RS10265 CNY67_RS04875a (9Z)-3-oxo- CNY67_RS07310 CNY67_RS00725 [+ 7 isozymes] I FolE2: spermidine dAdoMet D-glucosamine- carrier-protein] ribonuclease: acetyl phosphate acetyltransferase: cobT (7,8-dihydropterin- CNY67_RS10310 6-amino-6- CNY67_RS04875 CNY67_RS04875 [+ 2 isozymes] CNY67_RS04875 CNY67_RS05335 1-(β-D a [protein]- B: rpiB D-manno-heptose glucosamine-1- 7,8- Ins(3)P FabZ: fabZ α a very-long-chain a 5,10- acyl-carrier protein octadec-9- met D-ribulose CNY67_RS03625 enolpyruvate reductase: rnpA CNY67_RS13495 -ribazole 6-yl)methyl AMP diphosphate a [lipoyl-carrier protein]- deoxyfutalosine a 3-oxotetradecanoyl- a 3-oxotetracosanoyl- DNA without a 3-oxohexanoyl- fumarate ribofuranosyl) N-phospho- ADP- phosphate N- agmatinase: nicotinate fatty acyl-CoA methenyltetrahydrofolate enoyl-[acp] 6 type I dihydroneopterin spermine synthase: UDP-N- CNY67_RS04870 a (2E)-octadec- phosphate 5'-phosphate diphosphate N -lipoyl-L-lysine [acp] [acp] lesion [acp] L-histidine 5-phosphate glyceromanno- acetyltransferase: speB acetate kinase: nicotinamide glyceraldehyde- GDP-mannose biosynthesis 3'-triphosphate inositol CNY67_RS01960 acetylenolpyruvoylglucosamine 2-enoyl-[acp] acetyltransferase heptose 6- glmU ketoacyl-ACP an uncharged tRNA CNY67_RS13500 3-phosphate 6-carboxytetrahydropterin monophosphatase: S-methyl-5'- reductase: murB PlsX: triose-phosphate dehydrogenase: epimerase: rfaD D-glucopyranose UDP-N-acetyl- CNY67_RS07995 putrescine spermine synthase III: steroyl-[acp] synthase QueD: queD thioadenosine CNY67_RS04880 (4S)-4-hydroxy-2- a double a 1-phosphatidyl- a guanine 966 3-octaprenyl-4- 1-oleyl-2-lyso- phosphoenol isomerase: gap 6-phosphate α-D-glucosamine UDP-N-acetyl- CNY67_RS04875 reductase: acetate phenylacetate β-D-fructofuranose 1-phosphate 2-methylbutanoate ethylnitronate a (5Z)-tetradec- an aldehyde acryloyl-CoA ADP- glucose-6- 6-carboxy-5,6,7,8- myo-inositol ala α CNY67_RS06415 a malonyl-[acp] oxoheptanedioate stranded DNA 1D-myo-inositol in 16S rRNA hydroxybenzoate a decanoyl-[acp] phosphatidate pyruvate CNY67_RS07980 -D-muramate a 3-oxohexadecanoyl- phenylacetate--CoA fructose-1,6-bisphosphate acetate- nitronate 5-enoyl-[acp] D-glyceraldehyde glyceromanno- phosphate tetrahydropterin Glu ketoacyl-ACP 2,4-dihydroxyhept- phosphatidylinositol 16S rRNA 3-octaprenyl-4- 1-acyl-sn-glycerol- aldehyde crotonyl-CoA DHAP 3-phosphate heptose 6- [acp] ligase: CNY67_RS12480 aldolase, class II: fba -CoA monooxygenase: 2-ene-1,7-dioic endonuclease I: (guanine(966)-N(2) hydroxybenzoate ketoacyl-ACP 3-phosphate ferredoxin carboxylase/ pyruvate isomerase: α UDP-N- a stearoyl-[acp] synthase III: kinase: UDP- -D-glucuronate 5-oxo-L-proline metabolism ligase: acs CNY67_RS07490 CNY67_RS05985 synthase III: kinase: pyk epimerase: rfaD CNY67_RS09965 glutamate acetylmuramate-- 3-oxoacyl-[acyl- [+ 3 isozymes] fructose-bisphosphate [unspecified CNY67_RS04875a (7Z)-3-oxo- acid aldolase: CNY67_RS13080 )-methyltransferase carboxy-lyase: acyltransferase: oxidoreductase: reductase: β biosynthesis (from C1 Compound Utilization and Assimilation CNY67_RS04875 ADP-L-glycero- - F6P racemase: L-alanine ligase: carrier-protein] an N-terminal aldolase: CNY67_RS12565 2-methylbutanoyl- degradation nitrite acetaldehyde CNY67_RS01865 a 1-phosphatidyl- 2 RsmD: rsmD CNY67_RS10480 CNY67_RS08030 CNY67_RS03575 ccrA UDP-glucose) diphosphate AMP phenylacetyl-CoA AMP diphosphate acyl-carrier protein hexadec-7- succinate a 5'-phosphooligonucleotide an N - a 3- dioleoyl (R)-methylmalonyl- pyruvate D-manno-heptose 7-carboxy-7- murI CNY67_RS06715 reductase: L-glutaminyl- an N-terminal L- D-glyceraldehyde DHAP CoA products] pyruvate 1D-myo-inositol 966 2-octaprenylphenol a carboxylate fructose-1,6- UDP-α-D-glucose enoyl-[acp] semialdehyde methylguanine oxododecanoyl- phosphatidate CoA mannose-1-phosphate deazaguanine UDP-N-acetyl- CNY67_RS04870 [protein] glutamyl-[protein] formate assimilation 4-phosphate bisphosphate UDP-glucose/ formate in 16S rRNA [acp] α guanylyltransferase/ UDP-α-D-glucose D-glt α-D-muramoyl- a (3R)-3- stearate into 5,10- aldolase, UDP-N-acetyl- -D- GDP-mannose 7-cyano-7- oxidation to CO mannose-6- biosynthesis I L-alanine hydroxyhexadecanoyl- methylenetetrahydrofolate 2 class II: fba mannosaminouronate dehydrogenase deazaguanine RNase G phosphate isomerase: [acp] long-chain fatty CoB-CoM a 2,3,4-saturated a (3Z)-dodec- MoO - 1-myristoylglycerol pyridoxamine biosynthesis D-glucopyranose synthase formate formate dihydromethanophenazine a 5-methyltetrahydrofolate isovalerate 2 uroporphyrinogen-III a [protein] Ser/Thr degradation Ins(6)P cobyrinate riboflavin fructose- UDP-N-acetyl- CNY67_RS13005 family protein: UDP-N- 3-hydroxyacyl- acid--CoA ligase: a [protein] with heterodisulfide fatty acid a malonyl-[acp] molybdopterin ATP 3-phosphate 5'-phosphate 6-phosphate QueC: queC γ formate-- thiosulfate heterodisulfide long-chain fatty 3-enoyl-[acp] substrate mRNA bifunctional bisphosphate α-D-glucosamine D-mannopyranose alpha-D-glucose α CNY67_RS07175 acetylmuramoyl- [acyl-carrier- CNY67_RS08360 an N-terminal 5- -L-glutamyl 5,10- acetate--CoA ketoacyl-ACP cofactor uroporphyrinogen-III serine/threonine 1-acyl-sn-glycerol- pyridoxamine 5'- inositol cobyrinate a,c- UDP-N- UDP- -D- glutathione tetrahydrofolate reductase: reductase subunit acid--CoA ligase: molybdenum cofactor riboflavin kinase/ aldolase: 6-phosphate phosphate-specific preQ L-alanine-- protein] oxo-L-proline 5-phosphate methylenetetrahydrofolate ligase: acs synthase III: C-methyltransferase: protein kinase: 3-phosphate ribonuclease E: phosphate oxidase: monophosphatase: diamide synthase: acetylglucosamine glucuronate 0 stearoyl-CoA ligase: CNY67_RS04550 A: CNY67_RS01445 CNY67_RS08360 guanylyltransferase: FAD synthetase: CNY67_RS12565 phosphoglucomutase: D-glutamate dehydratase reductase: CNY67_RS02075 CNY67_RS04875a (5Z)-3-oxo- cobA CNY67_RS06555 acyltransferase: CNY67_RS10275 CNY67_RS11740 CNY67_RS07995 CNY67_RS00150 2-epimerase: phosphomannomutase: 10CNY67_RS08565 CO adenylyl CNY67_RS11555 ligase: murD FabZ: fabZ an N - 2 [+ 4 isozymes] a 5,10- a 2,3,4-saturated isovaleryl-CoA AMP diphosphate a [protein] (L-serine/L- CNY67_RS08030 cob(II)yrinate CNY67_RS12710 CNY67_RS05580 CNY67_RS13010 α-D-glucopyranoseCNY67_RS07810 Aromatic Compound Biosynthesis AMP diphosphate acyl-carrier protein tetradec-5- molybdenum precorrin-2 dimyristoyl myo-inositol UDP-N-acetyl-α- formyltetrahydrofolate methanophenazine coenzyme M coenzyme B methylenetetrahydrofolate fatty acyl CoA enoyl-[acp] threonine) phosphate an mRNA fragment PLP a,c-diamide FMN α-D-mannose 1-phosphate UDP-N-acetyl- a (2E)-hexadec- cofactor phosphatidate β-D-fructose 1,6- D-mannosamine meso- bifunctional 1-phosphate α-D-muramoyl-L- chorismate biosynthesis 2-enoyl-[acp] 5-oxo-L-proline bisphosphate UDP-N-acetyl-D- UTP--glucose- diaminopimelate 5,10-methylene- UDP-α-D- alanyl-D-glutamate from 3-dehydroquinate salicylate biosynthesis I mannosamine mannose-1-phosphate 1-phosphate palmitoyl-[acyl- 38- fructose-1,6- hydantoinase/ tetrahydrofolate a [carboxyl-carrier protein dimer]- 10 a uridine galactose acetyl-CoA an N - an L-methionyl- α-linolenate S-methyl-L- carboxynorspermidine 1-aminocyclopropane- a ribonucleoside pyridoxine 3-ethylmalate crotonyl-CoA dehydrogenase: guanylyltransferase: uridylyltransferase: carrier-protein] dehydrogenase/ 6 propanoyl-CoA phosphate L-homocysteine VibB coenzyme A Ins(1)P bisphosphatase: biosynthesis UDP-N- 3-dehydroquinate chorismate oxoprolinase: N -carboxybiotinyl-L-lysine formyltetrahydrofolate [initiator tRNA Met ] methionine 1-carboxylate 40 in tRNA 5'-monophosphate 5'-phosphate CNY67_RS07870 CNY67_RS05585 CNY67_RS13005 galU reductase: CNY67_RS01375 5,10-methylene- acetyl-CoA carboxylase: methionyl-tRNA long-chain fatty phosphate homocysteine S- holo-[acyl- tRNA 3-isopropylmalate crotonyl-CoA α α acetylmuramoyl- Isochorismate D-cysteine 5'-nucleotidase pyridoxamine 5'- inositol UDP-N-acetyl-α-D- UDP- -D-glucose GDP- -D- α type II 3- CNY67_RS06415 phosphatidylethanolamine tetrahydrofolate CNY67_RS12115 acid--CoA ligase: propanoyltransferase: carboxynorspermidine pseudouridine(38- carboxylase/ UDP- -D-glucose L-alanyl-D- synthase (salicylate formyltransferase: methyltransferase: carrier-protein] SurE: phosphate oxidase: monophosphatase: dehydrogenase: F6P mannosaminuronate UDP-glucose mannose dehydroquinate biosynthesis I cyclohydrolase: acetyl-CoA carboxylase: CNY67_RS08360 CNY67_RS08930 decarboxylase: nspC desulfhydrase: 40) synthase TruA: reductase: glutamate--2, 6- biosynthesis): a palmitoyl-[acp] Glu an N-formyl- CNY67_RS00055 CNY67_RS06070 synthase: acpS CNY67_RS00725 CNY67_RS11740 CNY67_RS07995 leuB 4-epimerase dehydratase: aroQ CNY67_RS00995 CNY67_RS12125 propanoyl a holo-[VibB aryl- CNY67_RS12570 CNY67_RS10750 ccrA L-methionyl- a tetrahydrofolate met 3',5'-ADP 38- glucose-6- GalE: galE diaminopimelate CNY67_RS08830 a CDP-diacylglycerol a [biotin carboxyl-carrier-protein AMP diphosphate α-linolenoyl-CoA phosphate norspermidine a pseudouridine a ribonucleoside myo-inositol 2-oxovalerate (2S)- a 5,10- malonyl-CoA met carrier protein] 2-oxobutanoate PLP phosphate UDP-α-D-galactose ligase: isochorismate CDP-diacylglycerol--serine dimer]-N 6 -biotinyl-L-lysine [initiator tRNA ] 40 in tRNA ethylmalonyl-CoA D-ala 3-dehydroshikimate isomerase: CNY67_RS06685 O-phosphatidyltransferase: methenyltetrahydrofolate Amino Acid Degradation CNY67_RS09965 Nucleoside and Nucleotide Biosynthesis shikimate isochorismate- bifunctional pssA N-end rule pathway I (prokaryotic) D-alanine--D- pyruvate lyase: a 2,3,4-saturated a peptide with α D-glucopyranose UDP-N-acetyl- dehydrogenase: palmitate a 3-sn-phosphatidyl-L-serine 5,10-methylene- glycine cleavage phosphatidylglycerophosphate 3-aci- an N-modified a peptide with a Kdo CTP CDP- -D-glucose α alanine ligase: CNY67_RS08835 L-methionine degradation pristanate CTP 1,2-diacyl-sn- an N-terminal formate D-threo-isocitrate Ins(2)P MeOH N5-CAIR predicted 6-phosphate guanosine ribonucleotides pyrimidine deoxyribonucleotides de novo biosynthesis III -D-muramoyl- CNY67_RS01600 leucyl/phenylalanyl- tetrahydrofolate (1-octadecenoyl(9Z), 2-palmitoyl) nitropropanoate aminoacyl-[tRNA] leader sequence CDP-glucose 4,6- superpathway of pyrimidine xanthine and γ CNY67_RS09820 long-chain fatty phosphatidylserine a [glycine-cleavage I (to L-homocysteine) nitronate long-chain fatty glycerol 3-phosphate 3-deoxy-manno- formate NADP-dependent 5-(carboxyamino) ABC de novo biosynthesis superpathway of 5-aminoimidazole adenine and adenosine salvage III L-alanyl- -D- salicylate tRNA--protein dehydrogenase/ phosphatidate Xaa-L-prolineleucyl aminoacyl-tRNA signal inositol adenosine nucleobases salvage xanthosine salvage shikimate acid--CoA ligase: decarboxylase proenzyme: complex H protein] phosphatidylglycerophosphatase monooxygenase: acid--CoA ligase: octulosonate dehydrogenase- dehydratase: rfbG isocitrate catalase: imidazole met transporter met UDP CTP ribonucleotide biosynthesis glutamyl-meso-2,6- D-alanyl-D-alanine transferase: 5,10-methylene- glycine cytidylyltransferase: aminopeptidase: hydrolase: peptidase monophosphatase: ribonucleotides de CNY67_RS08360 CNY67_RS11865 a [protein] N 6 -lipoyl-L-lysine A: CNY67_RS11900 CNY67_RS07490 CNY67_RS08360 cytidylyltransferase: N subunit CDP-glucose 4,6- dehydrogenase: CNY67_RS09490 ribonucleotide of L- ribonucleoside- uracil diaminopimelate shikimate kinase: an N-terminal CNY67_RS06160 tetrahydrofolate dehydrogenase met [unspecified CNY67_RS11790 a peptide with CNY67_RS01040 CNY67_RS06005 I: lepB CNY67_RS07995 IMP PRPP novo biosynthesis N-terminal L- methionine a CDP-2,3,4-saturated- a proteinogenic an N-modified an uncharged CNY67_RS01875 alpha: fdnG dehydratase: rfbG CNY67_RS00560 mutase: purE methionine diphosphate reductase, adenine uracil xanthosine CNY67_RS02270 palmitoyl-CoA an L-1-phosphatidylethanolamine arginyl-[protein] cyclohydrolase: (aminomethyl- 1-oleoyl-2-palmitoyl- degradation nitrite 3-oxopropanoate an N-terminal a leader sequence a peptide CDP-4-dehydro- IMP CDP amidophosphoribosyltransferase: UDP-N- leucyl-L-arginine CNY67_RS00995 transferring): adenosyltransferase: AMP diphosphate pristanoyl-CoA diacylglycerol amino acid amino acid tRNA CMP-Kdo an electron- CO 2-oxoglutarate myo-inositol formaldehyde CAIR adenosylcobalamin- purine-nucleoside phosphoribosyltransferase: phosphatidylglycerol products] L-proline 2 CNY67_RS00035 IMP asp purine-nucleoside shikimate transfer quinol 6-deoxy-D-glucose dehydrogenase: dependent: phosphorylase: CNY67_RS07645 acetylmuramoylalanyl- dihydrolipoyl CNY67_RS10290 CNY67_RS14985 ribonucleoside- phosphorylase: kinase AroL: a 5,10- SAM CNY67_RS03390 CNY67_RS03250 amidophosphoribosyltransferase: CNY67_RS12110 adenylosuccinate D-glutamyl-2, 6- 4-hydroxyphenylpyruvate leucyl/phenylalanyl- dehydrogenase: glycine XMP diphosphate reductase, bifunctional pyr operon CNY67_RS12110 CNY67_RS01175 methylenetetrahydrofolate CNY67_RS03795 adenosine synthetase: diaminopimelate--D- biosynthesis tRNA--protein 6 dUDP adenosylcobalamin- 5-phospho-β- transcriptional regulator/uracil xanthine lpdA dehydrogenase 34 an O - an N-formyl-L- CNY67_RS14565 alanyl-D-alanine ligase: shikimate 3- transferase: 1-(3-sn-phosphatidyl)- a 5-carboxymethylaminomethyluridine a [protein]- a single a ribonucleoside a reduced a [glycerolipid]- 5,6-dihydrouracil 3-oxo- ethanol dependent: D-ribosylamine phosphoribosyltransferase: dihydrolipoyl (decarboxylating): DL-allothreonine Leu methylguanine methionylaminoacyl- superoxide Ins(5)P D-cysteine xanthosine-5'- nucleoside-diphosphate adenosine deaminase: adenylo-succinate CNY67_RS06690 phosphate CNY67_RS06160 a [protein] sn-glycerol 3-phosphate in tRNA L-cysteine stranded DNA triphosphate rubredoxin ATP an mRNA oleate icosatrienoyl-CoA CNY67_RS03250 phosphoribosylamine- CNY67_RS09645 tyr an N-terminal dehydrogenase: a [glycine-cleavageCNY67_RS10295 tRNA (cytidine(34) in DNA DNA repair tRNA peptide DNA cyclopropane-fatty- hydantoinase/ 3-oxoacyl-[acyl- phosphate:L- kinase: CNY67_RS09705 CNY67_RS04920 N-terminal L- a [glycine-cleavage serine desulfoferrodoxin: inositol catalase: D-cysteine adenylosuccinate UMP 3-phosphoshikimate 1- aspartate/ L-lysyl-[protein] lpdA complex H protein] N 6 - phosphatidylglycerophosphatase -2'-O)- deformylase: primase: polynucleotide acyl-phospholipid carrier-protein] -glycine ligase: leucyl-L-lysine 6 hydroxymethyltransferase: glyA protein RadA: CNY67_RS02060 oxoprolinase: monophosphatase: glutamine dUTP dCDP nicotinate-nicotinamide lyase: UDP-N-acetyl- carboxyvinyltransferase: complex H protein] N SAH A: CNY67_RS11900 methyltransferase: adenylyltransferase: synthase: reductase: CNY67_RS09490 desulfhydrase: CNY67_RS15170 UMP kinase: α tyrosine/aromatic aminomethyldihydrolipoyl- CNY67_RS06140 def dnaG an oxidized CNY67_RS01375 CNY67_RS07995 amido-ligase nucleotide CNY67_RS00530 -D-muramoyl- CNY67_RS01430 -dihydrolipoyl-L-lysine gly acetaldehyde CNY67_RS01380 a [protein]-S- a L-methionylaminoacyl- ssDNA/pppN(pN) CNY67_RS05200 CNY67_RS03260 CNY67_RS04870 CNY67_RS12570 dUTP diphosphatase: nucleoside-diphosphate XMP γ aminotransferase: L-lysine a guanine in DNA formate (AMP-forming): GAR adenylyltransferase: CNY67_RS11770 L-alanyl- -D- an L-1-phosphatidyl- a 5-carboxymethylaminomethyl- methyl-L-cysteine tRNA hybrid rubredoxin an mRNA a [phospholipid]- 3-ureidopropanoate 3R-hydroxy- myo-inositol acetaldehyde CNY67_RS02360 kinase: CNY67_RS09705 3-phosphoshikimate 1- CNY67_RS03680 adenosylhomocysteinase: n -1 pyruvate CNY67_RS03385 (d)CMP kinase: guanine and guanosine salvage glutamyl-meso-2,6- di-trans,octa-cis sn-glycerol 2'-O-methyluridine 34 in tRNA Leu dihydrosterculate icosatrienoyl-CoA nucleoside triphosphate CNY67_RS12230 AMP carboxyvinyltransferase: 4-hydroxyphenylpyruvate CNY67_RS00210 dCTP CNY67_RS10435 diaminopimeloyl- -undecaprenyl Respiration pyrophosphohydrolase: D-alanyl-D-alanine CNY67_RS12550 GMP UDP phosphate 4 CNY67_RS11565 inosine 5-enolpyruvoyl- L-homocysteine an O - an electron- adenosyl- guanosine aminomethyltransferase: a sulfurated lysine within quinoxaline-2- a [protein]- + + 2-(4-hydroxyphenyl) meso- an L-cysteinyl- adenylate kinase: nucleoside-diphosphate shikimate 3- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA SAM dethiobiotin an octanoyl-[acp] acyl-carrier protein methylthymine NADH H NADH menadione H a protein cobyrinate Ins(4)P meso-tartrate ala dUMP FGAR purine-nucleoside phospho-N- gcvT [sulfur carrier] gcv protein H carboxyl adenylate L-cysteine transfer quinone -2-oxoacetate diaminopimelate [tRNA Cys ] guanylate kinase: purine-nucleoside CNY67_RS02365 kinase: CNY67_RS09705 phosphate in DNA oxidoreductase: oxidoreductase: a,c-diamide CMP phosphorylase: pyrimidine deoxyribonucleotide acetylmuramoyl- an [apo BCAA biotin lipoyl(octanoyl) acyl carrier protein: DNA repair endopeptidase La: benzoylformate diaminopimelate aminoacyl-tRNA cobyric acid inositol tartrate alanine CNY67_RS09190 thymidylate synthase phosphoribosylformylglycinamidine phosphorylase: chorismate CNY67_RS04495 CNY67_RS04495 phosphorylation UTP CNY67_RS12110 phosphorylation pentapeptide- dehydrogenase synthase transferase: lipB CNY67_RS04865 protein RadA: CNY67_RS10760 decarboxylase: dehydrogenase: hydrolase: synthase CobQ: monophosphatase: dehydrogenase: transaminase: complementing protein synthase: CNY67_RS02615 CNY67_RS12110 ADP synthase: a [glycine-cleavage [+ 3 isozymes] [+ 2 isozymes] guanine transferase: E2 protein] N 6 3-methyl-2- BioB: bioB a quinoxaline-2- CNY67_RS06140 CNY67_RS04215 CNY67_RS06005 CNY67_RS07995 CNY67_RS14865 ThyX: CNY67_RS11355 CNY67_RS14990 L-serine degradation an unsulfurated acyl-carrier protein complex H protein] a [protein]-S- an electron- + + a peptide a peptide CNY67_RS07015 CNY67_RS01200 CNY67_RS15120 CMP phosphoribosylformylglycinamidine CTP synthetase: pyrG dTMP dCMP L-arginine degradation III AMP carboxyl-[aryl- NAD menadiol NAD Cys 2-hydroxy-3- GDP CNY67_RS06695 -lipoyl-L-lysine oxobutanoate L-threonine met 5'-deoxyadenosine biotin 6 a thymine in DNA (S)-2,3,4,5- a tRNA cys (d)CMP kinase: hypoxanthine dTMP kinase: (d)CMP kinase: (arginine decarboxylase/ [sulfur carrier] N -octanoyl-L-lysine methyl-L-cysteine transfer quinol 4-hydroxybenzaldehyde adenosylcobyrate myo-inositol pyruvate dTMP synthase: CNY67_RS07485 ATP synthase chorismate 3-methyl-2- dehydrogenase degradation II carrier protein] tetrahydrodipicolinate oxosuccinate CNY67_RS10435 CTP hypoxanthine CNY67_RS00715 CNY67_RS10435 agmatinase pathway) nucleoside- dTMP kinase: subunit: undecaprenyldiphospho- oxobutanoate subunit VorB: ser CDP FGAM CNY67_RS14490 phosphoribosyltransferase: hpt dTDP dCDP N-acetylmuramoyl-L- diphosphate CNY67_RS00715 hypoxanthine dehydrogenase CNY67_RS00775 thr L-serine alanyl-γ-D-glutamyl-meso arg nucleoside- phosphoribosyltransferase: hpt [+ 8 isozymes] nucleoside- nucleoside- subunit VorB: 2503 orotidine 5'- + + a myo-inositol 3-[(4'-methylthio) kinase: dTDP phosphoribosylformylglycinamidine ammonia-lyase: biosynthetic adenine in 23S rRNA 3-methyl-2-oxobutanoate icosapentaenoate coenzyme A FMN NAD(P)H H FMNH NAD O-ureido-L- asp phenylglyoxylate an aldehyde ser diphosphate GMP diphosphate diphosphate -2,6-diaminopimeloyl- CNY67_RS00775 4'-phosphopantetheine ATP phosphate 2 monophosphate L-saccharopine butyl]malate CNY67_RS09705 cyclo-ligase: CNY67_RS03220 2-aminoprop-CNY67_RS15095 arginine 23S rRNA (adenine(2503) 3-methyl-2-oxobutanoate long-chain fatty NADPH-dependent NADPH-dependent homoserine nucleoside-diphosphate kinase: ATP kinase: kinase: D-alanyl-D-alanine an [apo BCAA orotate argininosuccinate inositol saccharopine 3-isopropylmalate benzoylformate aldehyde IMP [+ 2 isozymes] an [apo BCAA dehydrogenase L-2-amino-3- 2-enoate decarboxylase: -C(2))-methyltransferase dehydrogenase subunit pantetheine-phosphate acid--CoA ligase: FMN reductase: FMN reductase: L-serine kinase: CNY67_RS09705 CNY67_RS09705 CNY67_RS09705 CNY67_RS09705 undecaprenyldiphospho- dehydrogenase phosphoribosyltransferase: synthase: monophosphatase: dehydrogenase: dehydrogenase: decarboxylase: oxidoreductase: GTP AIR 6 oxobutanoate CNY67_RS09670 RlmN: CNY67_RS12205 ammonia-lyase: muramoylpentapeptide beta-N- 6 E2 protein] N -S-[2- VorB: CNY67_RS00775 adenylyltransferase: pyrE CNY67_RS08360 CNY67_RS03800 CNY67_RS03800 dTTP E2 protein] N agmatine icosapentaenoyl- CNY67_RS06625 CNY67_RS07995 CNY67_RS00700 leuB CNY67_RS04215 CNY67_RS03300 CTP dTTP dCTP methylpropanoyl]dihydrolipoyl- CNY67_RS01935 + + CNY67_RS15095 acetylglucosaminyltransferase: -dihydrolipoyl- 8-amino-7- a 2-methyladenine 2503 in 23S rRNA 5'-deoxyadenosine met NADH CO isobutanoyl-CoA orotate PRPP NAD(P) FMNH H NADH FMN canavaninosuccinate 7-(methylthio)-2- 2 3'-dephospho-CoA CoA 2 allysine Glu benzaldehyde a carboxylate murG L-lysine L-lysine oxononanoate myo-inositol oxoheptanoate pyruvate lipid II (meso agmatinase: synthase: 2-iminopropanoate speB diaminopimelate CNY67_RS01805 containing) putrescine phosphoenol an [HPr]- RNase III mRNA 34 RNase E degradation 3-[(7'-methylthio) a proteinogenic 2+ a cytidine an L-asparaginyl- orotidine 5'- 3-methyl-2- Fermentation gly pyruvate glutathione processing a [glutamine- thiosulfate dithioerythritol sirohydrochlorin Co lys D-glycerate methylglyoxal amino acid pyruvate L-histidine ATP in tRNA Ile2 substrate mRNA [tRNA Asn ] heptyl]malate phosphate oxobutanoate pyruvate, phosphate phosphoenolpyruvate- substrate synthetase]-L-tyrosine thiosulfate sirohydrochlorin gamma- ribonuclease tRNA(Ile)-lysidine aminoacyl-tRNA 3-isopropylmalate glycerate orotidine-5'- dehydrogenase L-aspartate pyruvate dikinase: CNY67_RS04680 -protein adenylyltransferase: reductase: cobaltochelatase: ribonuclease E: glyoxalase: pyruvate fermentation glutamyltransferase: ggt III: rnc synthetase: hydrolase: dehydrogenase: dehydrogenase: phosphate subunit VorB: degradation I α γ phosphotransferase: ptsP RNase III CNY67_RS03785 CNY67_RS04550 CNY67_RS07095 CNY67_RS10275 CNY67_RS14035 to ethanol I an -( -L-glutamyl) an [HPr protein]- a [glutamine synthetase]-O CNY67_RS14630 CNY67_RS06005 leuB CNY67_RS09920 decarboxylase: CNY67_RS00775 + L-cysteinyl-glycine 4,5-cis-dihydroxy- cobalt- 34 L-glutamine diphosphate AMP phosphoenolpyruvate H -L-amino acid π an mRNA fragment processing sulfite a lysidine Asn L-asparagine N -phospho- pyruvate 4 -(5'-adenylyl)-L-tyrosine tRNA asn 10-(methylthio)- CNY67_RS09195 degradation I product mRNA 1,2-dithiacyclohexane sirohydrochlorin in tRNA Ile2 an mRNA fragment hydroxypyruvate (R)-lactate pyruvate asp degradation I L-histidine 2-oxodecanoate UMP aspartate aminotransferase: gln asn α Hydrogen Production glycyl radical a [glycine-cleavage RNase E mRNA -D- a [histone]-N 6 - 3-[(6'-methylthio) 3-[(5'-methylthio) CNY67_RS01635 imidazole glycerol a proteinogenic 2+ a (1->4)-α-D-glucan protein: asparaginase: SAM complex H protein] a sulfurated [sulfur carrier] leukotriene-C4 isobutanoate processing glucopyranose CTP protoporphyrin IX Mg a [histone]-L-lysine NaMN L-tartrate oxaloacetate aspartate/ phosphate synthase amino acid acetyl-L-lysine hexyl]malate pentyl]malate CNY67_RS06110 N 6 -octanoyl-L-lysine acetate--CoA substrate 1-phosphate histone magnesium 1,4-alpha-glucan hydrogen production III subunit HisH: CNY67_RS15290 lipoyl gamma- ribonuclease E: glucose-1-phosphate histone-lysine N- 3-isopropylmalate 3-isopropylmalate 5'-nucleotidase tartrate NAD-dependent tyrosine/aromatic ligase: acs deacetylase: chelatase: branching protein: CNY67_RS00505 asp synthase: lipA glutamyltransferase: ggt CNY67_RS10275 cytidylyltransferase: methyltransferase: dehydrogenase: dehydrogenase: SurE: dehydrogenase: malic enzyme 4: a reduced aminotransferase: a [glycine-cleavage α γ RNase E CNY67_RS00705 CNY67_RS13580 acetyl-CoA formate [+ 6 isozymes] an unsulfurated an -( -L-glutamyl) CNY67_RS08700 CNY67_RS00565 leuB leuB CNY67_RS00725 CNY67_RS14865 CNY67_RS05305 ferredoxin [iron- CNY67_RS03680 5'-deoxyadenosine met complex H protein] leukotriene-D4 isobutanoyl-CoA AMP diphosphate an mRNA fragment processing rfbF Mg- a (1,6)-α-D-glucosyl- oxaloacetate Glu [sulfur carrier] -L-amino acid CDP-α-D-glucose acetate a [histone]-L-lysine a [histone] N 6 - 9-(methylthio)- 8-(methylthio)- β-D- 2-hydroxy-3- formate RS05695 formate 6 protoporphyrin α pyruvate sulfur] clustercarbon monoxide- acetaldehyde N -lipoyl-L-lysine product mRNA (1,4)- -glucan methyl-L-lysine 2-oxononanoate 2-oxooctanoate ribosylnicotinate oxosuccinate induced dehydrogenase hydrogenase: (acetylating): a single- all-trans- a glucosylated CNY67_RS02770 CNY67_RS08920 5,10-methylene- 3-methyl-2- a [protein]- + 3-[(3'-methylthio) α Secondary Metabolite Degradation octaprenyl 4-hydroxybenzoate [DNA] a [protein]-L-lysine FMNH NADP canavaninosuccinate wound RNA -amylose pyruvate [+ 2 isozymes] tetrahydromethanopterin oxobutanoate stranded RNA L-glutamine 2 a protein a protein propyl]malate glycogenin H acetaldehyde 3-methyl-2-oxobutanoate polyribonucleotide diphosphate exodeoxyribonuclease transglutaminase: NADPH-dependent argininosuccinate beta-aspartyl- 3-isopropylmalate 1,4-alpha-glucan 1,4-alpha-glucan pyruvate 2 4-hydroxybenzoate peptidase S41: Detoxification hydroxymethyltransferase: nucleotidyltransferase: pnp III: xth CNY67_RS08120 FMN reductase: lyase: argH RNA helicase: branching protein: branching protein: D-galactarate octaprenyltransferase: a 2'- a protein with an CNY67_RS09695 peptidase: dehydrogenase: carboxylase: degradation I D-galactarate panB a nucleoside a single- CNY67_RS03800 CNY67_RS03845 CNY67_RS08700 CNY67_RS08700 CNY67_RS10995 deoxyribonucleoside [DNA] N 6 -(γ-glutamyl)- fumarate L-canavanine CNY67_RS00615 leuB CNY67_RS05210 degradation II reactive oxygen species degradation diphosphate stranded RNA 3-octaprenyl-4- + a peptide a peptide arginine dependent THMPT 2-dehydropantoate 5'-monophosphate L-lysine crosslink H NADPH FMN asp a protein 6-(methylthio)- a glycogen amylopectin D-galactarate hydroxybenzoate an unwound RNA oxaloacetate ethanol D-galactarate acid resistance 2-oxohexanoate NADH repair D-galactarate superoxide dehydratase: D-galactarate dehydratase: CNY67_RS15445 arg a single RNase R degradation a [protein]- an organic a (1->4)- a double a (1->4)- NADH 5-dehydro-4- CNY67_RS15445 superoxide dismutase: a 5-L-glutamyl- a [protein]-L-glutamine serotonin a 9S rRNA precorrin-2 Co 2+ carbonic acid D-glycerate 5-dehydro-4- biosynthetic stranded DNA glutathione hypoglycin A an amino acid substrate RNA L-cysteine hydroperoxide asp fumarate α-D-glucan stranded DNA α-D-glucan deoxy-D-glucarate CNY67_RS11660 exodeoxyribonuclease [peptide] ribonuclease sirohydrochlorin carbonic deoxy-D-glucarate arginine gamma- transglutaminase: ribonuclease E: peroxiredoxin: L-aspartate 1,4-alpha-glucan DNA gyrase 1,4-alpha-glucan VII large subunit: xseA gamma- R: rnr cobaltochelatase: anhydrase: glycerate kinase: hydrogen peroxide decarboxylase: glutamyltransferase: ggt CNY67_RS08120 CNY67_RS10275 ahpC oxidase: nadB branching protein: subunit A: branching protein: αglutamyltransferase: ggt a [protein] N 6 -[(5-hydroxy-1H an intra- CNY67_RS02905 Chemoautotrophic CNY67_RS09670 a single-stranded a ribonucleoside an -(5-L- a diribonucleotide a nucleoside 5'- an rRNA fragment a 5S rRNA an alcohol CNY67_RS07095 CNY67_RS08700 CNY67_RS00025 CNY67_RS01925 CNY67_RS08700 L-cysteinyl-glycine hypoglycin B -indol-3-yl)ethyl]-L-glutamine protein disulfide succinate 2-iminosuccinate Energy Metabolism tartronate agmatine oligodeoxyribonucleotide 5'-monophosphate a peptide glutamyl)- monophosphate cobalt-precorrin-2 a negatively CO H O 3-phospho- (R)-NADHX catalase: a GlgE-glycogen 2 2 starch semialdehyde 2,5- amino acid supercoiled DNA D-glycerate bifunctional hydrogen dioxopentanoate CNY67_RS09490 ADP-dependent oxidation NAD(P)-dependent oxidoreductase: H O hydroxyl radical NAD(P)H-hydrate I (aerobic) 2 10 D-sedoheptulose D-glyceraldehyde D-erythrose D-xylulose UTP 2'-deoxycytidine cytidine a (1->4)- O an N - + + a [protein] N-terminal- (2R,3S)-3- dehydratase/ CNY67_RS08695 2 AICAR glutathione glycyl-glycine a plastoquinone NAD(P)H H hydrogencarbonate H SAICAR H O α H formyltetrahydrofolate 7-phosphate 3-phosphate formyl-L-methionine 4-phosphate 5-phosphate nucleoside triphosphate isopropylmalate 2 2 -D-glucan NAD(P)H-hydrate 2 NAD(P)H-dependent cytidine deaminase: adenylosuccinate cytidine deaminase: Ni/Fe- D-glycerate 2-oxoglutarate phosphoribosylaminoimidazolecarboxamide gamma- transketolase: tkt carbonic anhydrase: peptide transketolase: tkt pyrophosphohydrolase: 3-isopropylmalate hydrogenase: 1,4-alpha-glucan epimerase: oxidoreductase: CNY67_RS04845 lyase: CNY67_RS04845 hydrogenase, b- formyltransferase: CNY67_RS14555 glutamyltransferase: ggt CNY67_RS01925 deformylase: def CNY67_RS11565 dehydrogenase: CNY67_RS10035 branching protein: CNY67_RS07165 γ-L-glutamyl- CNY67_RS00430 D-xylulose D-ribose 5- an N-terminal L- D-glyceraldehyde CNY67_RS00530 CNY67_RS08700 (S)-NADHX type cytochrome FAICAR a tetrahydrofolate L-cysteinyl-glycine H O CO formate F6P leuB H O glycylglycine + 5-phosphate phosphate 2 2 methionyl-[protein] 3-phosphate UMP 2'-deoxyuridine 2 uridine subunit: cybH NAD(P) a plastoquinol AICAR fumarate 4-methyl-2- a glycogen ATP-dependent hydrogenase: 2-phospho- oxopentanoate NADH-hydrate CNY67_RS10035 D-glycerate dehydratase: A(H2) CNY67_RS07165

NADH a branched- chain a basic an amino an amino an amino amino acid a dicarboxylate molybdate amino acid acid acid acid phosphate phosphate a branched- a branched- an L-sorbose 1-phosphate phosphonate D-serine a sugar 6- an inorganic phosphonate a C4- chain chain D-mannose D-fructose 1-phosphate glycine betaine D-ala cis-vaccenoyl-CoA an amino an amino a nucleotide benzoate (S)-lactate a polyamine a tricarboxylate acid H + acid phosphate Mg 2+ Mg 2+ Co 2+ an aromatic uracil phosphate anion phosphite dicarboxylate 6-phosphate gly a 2,3,4-saturated fatty acyl CoA + + + + + predicted amino acid amino acid D-mannose 6-phosphate gly phosphate H H H H H phosphate amino acid ABC predicted predicted predicted predicted predicted predicted predicted transporter predicted ABC ABC ABC ABC ABC ABC ABC ABC RS07650 RS07460 GrpE RS01680 RS04430 RS14855 RS13510 of a RS11760 BrnQ RS03450 RS07455 transporter of transporter RS10120 RS07520 RS01240 RS06460 RS14860 RS08360 RS02345 transporter transporter transporter RS14195 AtpE RS13700 RS14190 RS13705 RS14185 RS07730 RS05475 RS04430 RS10325 MgtA MgtE CbiQ RS11045 transporter transporter transporter branched- phosphonate of a basic of an of an of an of molybdate of phosphate of phosphate chain amino acid amino acid amino acid amino acid a branched- a branched- L-sorbose D-serine uracil a sugar an inorganic phosphonate a C4- amino acid D-mannose glycine betaine cis-vaccenate an amino + 2+ 2+ 2+ a nucleotide benzoate chain chain D-fructose D-ala (S)-lactate a polyamine a tricarboxylate H phosphate Mg Mg Co anion phosphite dicarboxylate gly a 2,3,4-saturated fatty acid acid H + H + H + H + H + an amino an aromatic amino acid amino acid D-mannose phosphonate gly phosphate phosphate molybdate a basic an amino an amino an amino acid phosphate phosphate amino acid a branched- amino acid acid acid acid chain a dicarboxylate amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.