A History of Cardiac Surgery
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October 24–26, 2021 2
SCIENCE · INNOVATION · POLICIES WORLD HEALTH SUMMIT BERLIN, GERMANY & DIGITAL OCTOBER 24–26, 2021 2 “No-one is safe from COVID-19; “All countries have signed up to Universal no-one is safe until we are all Health Coverage by 2030. But we cannot safe from it. Even those who wait ten years. We need health systems conquer the virus within their that work, before we face an outbreak own borders remain prisoners of something more contagious than within these borders until it is COVID-19; more deadly; or both.” conquered everywhere.” ANTÓNIO GUTERRES Secretary-General, United Nations FRANK-WALTER STEINMEIER Federal President, Germany “We firmly believe that the “All pulling together—this must rights of women and girls be the hallmark of the European are not negotiable.” Health Union. I believe this can NATALIA KANEM be a test case for true global Executive Director, United Nations Population Fund (UNFPA) health compact. The need for leadership is clear and I believe the European Union must as- sume this responsibility.” “The lesson is clear: a strong health URSULA VON DER LEYEN system is a resilient health system. Health President, European Commission systems and preparedness are not only “Governments of countries an investment in the future, they are the that are doing well during foundation of our response today.” the pandemic have not TEDROS ADHANOM GHEBREYESUS Director-General, World Health Organization (WHO) only shown political leader- ship, but also have listened “If we don’t address the concerns and to scientists and followed fears we will not do ourselves a favor. their recommendations.” In the end, it is about how technology SOUMYA SWAMINATHAN Chief Scientist, World Health can be advanced as well as how Organization (WHO) we can make healthcare more human.” BERND MONTAG President and CEO, Siemens Healthineers AG, Germany “The pandemic has brought to light the “Academic collabo ration is importance of digital technologies and in place and is really a how it can radically bridging partnership. -
Sir Charles Sherrington'sthe Integrative Action of the Nervous System: a Centenary Appreciation
doi:10.1093/brain/awm022 Brain (2007), 130, 887^894 OCCASIONAL PAPER Sir Charles Sherrington’sThe integrative action of the nervous system: a centenary appreciation Robert E. Burke Formerly Chief of the Laboratory of Neural Control, National Institute of Neurological Disorders, National Institutes of Health, Bethesda, MD, USA Present address: P.O. Box 1722, El Prado, NM 87529,USA E-mail: [email protected] In 1906 Sir Charles Sherrington published The Integrative Action of the Nervous System, which was a collection of ten lectures delivered two years before at Yale University in the United States. In this monograph Sherrington summarized two decades of painstaking experimental observations and his incisive interpretation of them. It settled the then-current debate between the ‘‘Reticular Theory’’ versus ‘‘Neuron Doctrine’’ ideas about the fundamental nature of the nervous system in mammals in favor of the latter, and it changed forever the way in which subsequent generations have viewed the organization of the central nervous system. Sherrington’s magnum opus contains basic concepts and even terminology that are now second nature to every student of the subject. This brief article reviews the historical context in which the book was written, summarizes its content, and considers its impact on Neurology and Neuroscience. Keywords: Neuron Doctrine; spinal reflexes; reflex coordination; control of movement; nervous system organization Introduction The first decade of the 20th century saw two momentous The Silliman lectures events for science. The year 1905 was Albert Einstein’s Sherrington’s 1906 monograph, published simultaneously in ‘miraculous year’ during which three of his most celebrated London, New Haven and New York, was based on a series papers in theoretical physics appeared. -
I86 Ms]BRH I
I i86 BRH [THE CENTENARY OF COLLEGE OF ms] THE SURGEONS. [JULY 21, 1900. In the of our LL.D., D.C.L., Professor of Clinical Surgery University of Laval; Surgeon- present state very limited knowledge of the General James Jameson, C.B., M.D., LL.D., Director-General, Army complicated processes which take place in the decomposition Medical Service; William Williams Keen, M.D., LL.D., Professor of the and ultimate oxidation of sewage, it is premature to dogma- Principles of Surgery and of Clinical Surgery, Jefferson Medical College, tise with regard to all the details of these but from Philadelphia; Theodor Kocher, Professor of Surgery, University of Bern; processes; Professor Dr. Franz Konig, Geh. Med. Bath, Berlin; Professor Dr. Ernst what is known with regard to the life-history of bacteria, it-is Georg Ferdinand Kuster, Geh. Med. Rath, Marburg: Elie Lambotte, plainly indicated that excessive anaerobic action may greatly Brussels; Odilon Marc Lannelongue, Professor of Surgical Pathology, modify and inhibit the work of anaerobic as well as of aerobic Faculty of Medicine of Paris; Kar Gustaf Lennander, M.D., Professor of Surgery and Obstetrics, University of Upsala; William Macewen, M.D. bacteria; that septic tanks and contact beds may become LL.D., F.R.S., Regius Professor of Surgery, University of Glasgow, " sewage sick" as well as the land used for sewage puri- Colonel Kenneth MacLeod, M.D., LL.D IMS Professor of Clinical fication. and Military Medicine, Armiy Medical School. Netley; Julius Nicolaysen, It is conceivable, therefore, that in cases in which the flow Professor of Surgery, Royal University of Christiania ; Sir Henry Frederick NorburY K.C.B., Director-General, Medical Department of the Royal of sewage to the septic tank is hindered and delayed by low Navy; Leopold Ollier, Professor of Clinical Surgery, UniversitY of Lyonos; gradients, or faulty conditions of the sewers, or other causes, Victor Pactioutine, President, Imperial Military Academy of Medicine, the interposition of a septic tank previous to treatment by St. -
Historical Evolution of Thyroid Surgery: from the Ancient Times to the Dawn of the 21St Century
World J Surg (2010) 34:1793–1804 DOI 10.1007/s00268-010-0580-7 Historical Evolution of Thyroid Surgery: From the Ancient Times to the Dawn of the 21st Century George H. Sakorafas Published online: 17 April 2010 Ó Socie´te´ Internationale de Chirurgie 2010 Abstract Thyroid diseases (mainly goiter) have been The chief legacy which a surgeon can bequeath is a gift recognized for more than 3500 years. Knowledge of the of the spirit. To inspire many successors with a firm nature of these diseases was, of course, limited at that time. belief in the high destiny of our calling, and with a Thyroid surgery was conceived by the ancients, but it was confident and unwavering intention both to search out limited to rare attempts to remove part of an enlarged the secrets of medicine in her innermost recesses, and thyroid gland in cases of impending death by suffocation to practice the knowledge so acquired with lofty pur- or, in very rare cases, of a suppurating thyroid. Like other pose, high ideals, and generous heart, for the benefit of fields of surgery, thyroid surgery was limited by many humanity—that is the best that a man can transmit. problems: the lack of anesthesia and antisepsis, the need Sir Berkeley Moynihan for appropriate instruments, mainly artery forceps (many deaths after thyroid surgery were due to severe postoper- ative hemorrhage or infection). Much of the progress in Introduction thyroid surgery occurred in Europe during the second half of the 19th century. During the first half of the 20th Surgical management of thyroid diseases evolved slowly century, the evolution of thyroid surgery accelerated sig- throughout the ages. -
Metchnikoff and the Phagocytosis Theory
PERSPECTIVES TIMELINE Metchnikoff and the phagocytosis theory Alfred I. Tauber Metchnikoff’s phagocytosis theory was less century. Indeed, the clonal selection theory and an explanation of host defence than a the elucidation of the molecular biology of the proposal that might account for establishing immune response count among the great and maintaining organismal ‘harmony’. By advances in biology during our own era5. tracing the phagocyte’s various functions Metchnikoff has been assigned to the wine cel- Figure 1 | Ilya Metchnikoff, at ~45 years of through phylogeny, he recognized that eating lar of history, to be pulled out on occasion and age. This figure is reproduced from REF. 14. the tadpole’s tail and killing bacteria was the celebrated as an old hero. same fundamental process: preserving the However, to cite Metchnikoff only as a con- integrity, and, in some cases, defining the tributor to early immunology distorts his sem- launched him into the turbulent waters of evo- identity of the organism. inal contributions to a much wider domain. lutionary biology. He wrote his dissertation on He recognized that the development and func- the development of invertebrate germ layers, I first encountered the work of Ilya tion of the individual organism required an for which he shared the prestigious van Baer Metchnikoff (1845–1916; FIG. 1) in Paul de understanding of physiology in an evolution- Prize with Alexander Kovalevski. By the age of Kruif’s classic, The Microbe Hunters 1.Who ary context. The crucial precept: the organism 22 years, he was appointed to the position of would not be struck by the description of this was composed of various elements, each vying docent at the new University of Odessa, where, fiery Russian championing his theory of for dominance. -
Schumann Romances
SCHUMANN ROMANCES ROBERT SCHUMANN (1810–1856) ROBERT SCHUMANN Drei Romanzen für Oboe und Klavier op. 94 (1849, erschienen/published 1849) Zwei Lieder, bearbeitet für Oboe und Klavier/Two songs, arranged for oboe and piano: 1 I Nicht schnell 03:30 15 „Meine Rose“ (Nikolaus Lenau) op. 90, Nr. 2 (Langsam, mit innigem Ausdruck) 2 II Einfach, innig – Etwas lebhafter – Im Tempo 03:58 (1850, erschienen/published 1850) 03:24 3 III Nicht schnell 04:37 16 „Mein schöner Stern“ (Friedrich Rückert) op. 101, Nr. 4 (Langsam) (1849, erschienen/published 1852) 02:16 Aus/From: Kinderszenen. Leichte Stücke für Klavier op. 15 (1838, erschienen/published 1839) Bearbeitung für Violine und Klavier von/Arranged for violin and piano by Emilius Lund (1870) 17 „Abendlied“ für Klavier zu drei Händen op. 85, Nr. 12 4 Nr. 7 Träumerei 02:24 (1849, erschienen/published 1850) 5 Nr. 8 Am Kamin 01:09 Bearbeitung für Oboe und Klavier/Arranged for oboe and piano (1870) 02:20 Studien für den Pedalflügel. Sechs Stücke in kanonischer Form op. 56 Aus/From: Fünf Stücke im Volkston für Violoncello und Klavier op. 102 (1845, erschienen/published 1845) (1849, erschienen/published 1851) Bearbeitung für Violine (Oboe), Violoncello und Klavier von/ Bearbeitung für Oboe und Klavier/Arranged for oboe and piano Arranged for violin (oboe), violoncello and piano by Theodor Kirchner (1888) 18 II Langsam 03:03 6 I Nicht zu schnell 02:18 19 III Nicht schnell, mit viel Ton zu spielen 03:27 7 II Mit innigem Ausdruck 03:40 20 IV Nicht zu rasch 01:57 8 III Andantino – Etwas schneller – Tempo I 01:39 9 IV Innig – Etwas bewegter 03:40 10 V Nicht zu schnell 02:10 CÉLINE MOINET Oboe 11 VI Adagio 03:06 NORBERT ANGER Violoncello (6–11) FLORIAN UHLIG Klavier/piano CLARA SCHUMANN (1819–1896) Drei Romanzen für Violine und Klavier op. -
Chirurgia 1 Mad C 4'2006 A.Qxd
History of Medicine Chirurgia (2020) 115: 7-11 No. 1, January - February Copyright© Celsius http://dx.doi.org/10.21614/chirurgia.115.1.7 The Man Behind Roux-En-Y Anastomosis Carmen Naum1, Rodica Bîrlã1,2, Cristina Gândea1,2, Elena Vasiliu2, Silviu Constantinoiu1,2 1Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2General and Esophageal Surgery Department, Center of Excellence in Esophageal Surgery, Saint Mary Clinical Hospital, Bucharest, Romania Corresponding author: Rezumat Rodica Birla, MD General and Esophageal Surgery Department, Center of Excellence in Esophageal Surgery, Sf. Maria César Roux (1857–1934) s-a născut în satul Mont-la-Ville din Clinical Hospital, Bucharest, Romania cantonul Vaud, Elveţia şi a fost cel de-al cincilea fiu, dintre cei 11, E-mail: [email protected] ai unui inspector şcolar. A studiat medicina la Universitatea din Berna şi i-a avut printre profesori pe Thomas Langhans în patologie şi pe Thomas Kocher în chirurgie. Roux, la fel ca mulţi chirurgi din acea perioadă a practicat chirurgia ginecologică, ortopedică, generală, toracică şi endocrină, dar a devenit celebru în chirurgia viscerală. El a dominat toate domeniile chirurgicale şi a influenţat chirurgia cu spiritul său inovator, dar contribuţia sa cea mai mare a fost anastomoza Roux-în-Y. Fiind un chirurg meticulos, dar care în acelaşi timp, opera repede, o persoană muncitoare, dedicată pacienţilor şi studenţilor săi, el şi-a găsit un loc în istoria medicinei. A murit în 1934, iar moartea sa bruscă a fost un motiv de doliu naţional în Elveţia. Cuvinte cheie: Roux, César Roux, Roux-în-Y, gastroenterostomy, istoria chirurgiei Abstract César Roux (1857–1934) was born in the village of Mont-la-Ville in the canton of Vaud, Switzerland and he was the fifth son, among 11 children, of an inspector of schools. -
Emil Von Behring (1854–1917) the German Bacteriologist
Emil von Behring (1854–1917) The German bacteriologist and Nobel Prize winner Emil von Behring ranks among the most important medical scientists. Behring was born in Hansdorff, West Prussia, as the son of a teacher in 1854. He grew up in narrow circumstances among eleven brothers and sisters. His desire to study medicine could only be realized by fulfilling the obligation to work as an military doctor for a longer period of time. Between 1874 and 1878 he studied medicine at the Akademie für das militärärztliche Bildungswesen in Berlin. In 1890, after having published his paper Ueber das Zustandekommen der Diphtherie- Immunität und der Tetanus-Immunität bei Thieren, he captured his scientific breakthrough. While having worked as Robert Koch’s scientific assistant at the Berlin Hygienic Institute he had been able to show – together with his Japanese colleague Shibasaburo Kitasato (1852–1931) – via experimentation on animal that it was possible to neutralize pathogenic germs by giving „antitoxins“. Behring demonstrated that the antitoxic qualities of blood are not seated in cells, but in the cell-free serum. Antitoxins recovered of human convalenscents or laboratorty animals, prove themselves as life-saving when being applied to diseased humans. At last – due to Behring’s discovery of the body’s own immune defence and due to his development of serotherapy against diphtheria and tetanus – a remedy existed which was able to combat via antitoxin those infectious diseases which had already broken out. Having developped a serum therapy against diphtheria and tetanus Behring won the first Nobel Prize in Medicine in 1901. Six years before, in 1895, he had become professor of Hygienics within the Faculty of Medicine at the University of Marburg, a position he would hold for the rest of his life. -
The Ninth Season Through Brahms CHAMBER MUSIC FESTIVAL and INSTITUTE July 22–August 13, 2011 David Finckel and Wu Han, Artistic Directors
The Ninth Season Through Brahms CHAMBER MUSIC FESTIVAL AND INSTITUTE July 22–August 13, 2011 David Finckel and Wu Han, Artistic Directors Music@Menlo Through Brahms the ninth season July 22–August 13, 2011 david finckel and wu han, artistic directors Contents 2 Season Dedication 3 A Message from the Artistic Directors 4 Welcome from the Executive Director 4 Board, Administration, and Mission Statement 5 Through Brahms Program Overview 6 Essay: “Johannes Brahms: The Great Romantic” by Calum MacDonald 8 Encounters I–IV 11 Concert Programs I–VI 30 String Quartet Programs 37 Carte Blanche Concerts I–IV 50 Chamber Music Institute 52 Prelude Performances 61 Koret Young Performers Concerts 64 Café Conversations 65 Master Classes 66 Open House 67 2011 Visual Artist: John Morra 68 Listening Room 69 Music@Menlo LIVE 70 2011–2012 Winter Series 72 Artist and Faculty Biographies 85 Internship Program 86 Glossary 88 Join Music@Menlo 92 Acknowledgments 95 Ticket and Performance Information 96 Calendar Cover artwork: Mertz No. 12, 2009, by John Morra. Inside (p. 67): Paintings by John Morra. Photograph of Johannes Brahms in his studio (p. 1): © The Art Archive/Museum der Stadt Wien/ Alfredo Dagli Orti. Photograph of the grave of Johannes Brahms in the Zentralfriedhof (central cemetery), Vienna, Austria (p. 5): © Chris Stock/Lebrecht Music and Arts. Photograph of Brahms (p. 7): Courtesy of Eugene Drucker in memory of Ernest Drucker. Da-Hong Seetoo (p. 69) and Ani Kavafian (p. 75): Christian Steiner. Paul Appleby (p. 72): Ken Howard. Carey Bell (p. 73): Steve Savage. Sasha Cooke (p. 74): Nick Granito. -
Nobel Laureate Surgeons
Literature Review World Journal of Surgery and Surgical Research Published: 12 Mar, 2020 Nobel Laureate Surgeons Jayant Radhakrishnan1* and Mohammad Ezzi1,2 1Department of Surgery and Urology, University of Illinois, USA 2Department of Surgery, Jazan University, Saudi Arabia Abstract This is a brief account of the notable contributions and some foibles of surgeons who have won the Nobel Prize for physiology or medicine since it was first awarded in 1901. Keywords: Nobel Prize in physiology or medicine; Surgical Nobel laureates; Pathology and surgery Introduction The Nobel Prize for physiology or medicine has been awarded to 219 scientists in the last 119 years. Eleven members of this illustrious group are surgeons although their awards have not always been for surgical innovations. Names of these surgeons with the year of the award and why they received it are listed below: Emil Theodor Kocher - 1909: Thyroid physiology, pathology and surgery. Alvar Gullstrand - 1911: Path of refracted light through the ocular lens. Alexis Carrel - 1912: Methods for suturing blood vessels and transplantation. Robert Barany - 1914: Function of the vestibular apparatus. Frederick Grant Banting - 1923: Extraction of insulin and treatment of diabetes. Alexander Fleming - 1945: Discovery of penicillin. Walter Rudolf Hess - 1949: Brain mapping for control of internal bodily functions. Werner Theodor Otto Forssmann - 1956: Cardiac catheterization. Charles Brenton Huggins - 1966: Hormonal control of prostate cancer. OPEN ACCESS Joseph Edward Murray - 1990: Organ transplantation. *Correspondence: Shinya Yamanaka-2012: Reprogramming of mature cells for pluripotency. Jayant Radhakrishnan, Department of Surgery and Urology, University of Emil Theodor Kocher (August 25, 1841 to July 27, 1917) Illinois, 1502, 71st, Street Darien, IL Kocher received the award in 1909 “for his work on the physiology, pathology and surgery of the 60561, Chicago, Illinois, USA, thyroid gland” [1]. -
Gerald Edelman - Wikipedia, the Free Encyclopedia
Gerald Edelman - Wikipedia, the free encyclopedia Create account Log in Article Talk Read Edit View history Gerald Edelman From Wikipedia, the free encyclopedia Main page Gerald Maurice Edelman (born July 1, 1929) is an Contents American biologist who shared the 1972 Nobel Prize in Gerald Maurice Edelman Featured content Physiology or Medicine for work with Rodney Robert Born July 1, 1929 (age 83) Current events Porter on the immune system.[1] Edelman's Nobel Prize- Ozone Park, Queens, New York Nationality Random article winning research concerned discovery of the structure of American [2] Fields Donate to Wikipedia antibody molecules. In interviews, he has said that the immunology; neuroscience way the components of the immune system evolve over Alma Ursinus College, University of Interaction the life of the individual is analogous to the way the mater Pennsylvania School of Medicine Help components of the brain evolve in a lifetime. There is a Known for immune system About Wikipedia continuity in this way between his work on the immune system, for which he won the Nobel Prize, and his later Notable Nobel Prize in Physiology or Community portal work in neuroscience and in philosophy of mind. awards Medicine in 1972 Recent changes Contact Wikipedia Contents [hide] Toolbox 1 Education and career 2 Nobel Prize Print/export 2.1 Disulphide bonds 2.2 Molecular models of antibody structure Languages 2.3 Antibody sequencing 2.4 Topobiology 3 Theory of consciousness Беларуская 3.1 Neural Darwinism Български 4 Evolution Theory Català 5 Personal Deutsch 6 See also Español 7 References Euskara 8 Bibliography Français 9 Further reading 10 External links Hrvatski Ido Education and career [edit] Bahasa Indonesia Italiano Gerald Edelman was born in 1929 in Ozone Park, Queens, New York to Jewish parents, physician Edward Edelman, and Anna Freedman Edelman, who worked in the insurance industry.[3] After עברית Kiswahili being raised in New York, he attended college in Pennsylvania where he graduated magna cum Nederlands laude with a B.S. -
BSH N-L 17 Autumn 04
ISSUE 17 WINTER 2004 British Society for Heart Failure NEWSLETTERNEWSLETTER British Cardiac Society Conference 2005 In this issue… This conference will take place in Manchester on This issue of the BSH Newsletter reports on 23–26 May 2005 and the BSH is delighted to have the consensus conference on mechanical circulatory received confirmation that we will be involved in even support (MCS) programmes in the UK, which more sessions this time! We will have five sessions, took place in Oxford, UK, on 2 July 2004. The day as follows (exact times/dates to be confirmed): conference included sessions on: • Pragmatic diagnosis of heart failure Background to MCS 1 Chairs: Henry Dargie/John Chambers/Fran Sivers Use of MCS in short-term circulatory assist 3 Bridge-to-transplantation or -recovery 5 • Heart failure with preserved systolic function Long-term treatment of heart failure 6 Chairs: John Cleland/Jackie Taylor How to proceed with MCS in the UK health system 8 • Sudden death in heart failure Chairs: Mick Davies/Janet McComb 7th BSH Autumn meeting 2004 – Reports • Tomorrow's world Chairs: Theresa McDonagh/Anne-Marie Seymour The newsletter reporting from this meeting (taking • How to manage acute heart failure place 25–26 November 2004) is estimated to be Chairs: tbc circulated to members in February/March 2005. There will also be an article in the British Journal of Detailed programmes will posted on the BSH website Cardiology in the Jan/Feb 2005 issue, focusing on in December and the printed programmes circulated specific issues from the meeting. to BSH members and Friends in the new year.