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(12) Patent Application Publication (10) Pub. No.: US 2007/0116831 A1 Prakash Et Al

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(12) Patent Application Publication (10) Pub. No.: US 2007/0116831 A1 Prakash Et Al US 20070116831A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2007/0116831 A1 Prakash et al. (43) Pub. Date: May 24, 2007 (54) DENTAL COMPOSITION WITH Publication Classification HIGH-POTENCY SWEETENER (51) Int. Cl. (75) Inventors: Indra Prakash, Alpharetta, GA (US); A2.3L I/236 (2006.01) Grant E. DuBois, Roswell, GA (US) (52) U.S. Cl. .............................................................. 426/548 Correspondence Address: SUTHERLAND ASBILL & BRENNAN LLP (57) ABSTRACT 999 PEACHTREE STREET, N.E. ATLANTA, GA 30309 (US) The present invention relates generally to dental composi tions comprising non-caloric or low-caloric high-potency (73) Assignee: THE COCA-COLA COMPANY., Sweeteners and methods for making and using them. In Atlanta, GA (US) particular, the present invention relates to different dental compositions comprising at least one non-caloric or low (21) Appl. No.: 11/556,052 caloric natural and/or synthetic high-potency Sweetener, at (22) Filed: Nov. 2, 2006 least one Sweet taste improving composition, and an active dental Substance. The present invention also relates to dental Related U.S. Application Data compositions and methods that can improve the tastes of non-caloric or low-caloric natural and/or synthetic, high (60) Provisional application No. 60/739,302, filed on Nov. potency Sweeteners by imparting a more Sugar-like taste or 23, 2005. Provisional application No. 60/739,124, characteristic. In particular, the dental compositions and filed on Nov. 23, 2005. Provisional application No. methods provide a more Sugar-like temporal profile, includ 60/805.216, filed on Jun. 19, 2006. Provisional appli ing Sweetness onset and Sweetness linger, and/or a more cation No. 60/805,209, filed on Jun. 19, 2006. Sugar-like flavor profile. : : - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Patent Application Publication May 24, 2007 Sheet 2 of 5 US 2007/0116831 A1 ---' v- - - - - - - - - - - - - - - ww rrr,www.wak w... rt. la s n O) sys- rarvarur s w Nissassiss's S. www. ***** wer : www.swww'ss's ... : S. www.am WY Yas ...ar ress a . ...yyyyyyar & Tarawa. S. r S&-- wners: as SSSS Srrrrrrrrrrrrrrrrrrrr.-A-W-SSSSSSSS &Sissyr -- c- ----------Yaa-classsssss-s-s-s-s-rry . YYYYYYYYYYYYY-------------arrara-arrarars S. s Nkx &wS S... r s1 Patent Application Publication May 24, 2007 Sheet 3 of 5 US 2007/01 16831 A1 '. ."K"'ss's'ssww'ss'ssssssssssssss-s-swr’s-s-s-s-s-s-s-s-s-s-s-s-s-s-srxx x . ... assassis................-. -------.S. s ss 8 s s: *. 8 ... 8 SS & . 8 8 is- O) ...a...as - r. A. ------. was Ts. a. w v, Sh SS". w s w w s S ... ', s Patent Application Publication May 24, 2007 Sheet 4 of 5 US 2007/0116831 A1 Y--------,-,-,-,-,-,-,-,-,-,-,-sasssssssssssss------------------------- s& & O) t -- v wn-Yvv. WMMwww.SSS &&Sys:'''''''''''''''''' a' . A. 's------------------------ . Patent Application Publication May 24, 2007 Sheet 5 of 5 US 2007/01 16831 A1 &~~~~#~~~~~*~?ae sessitarsasterseystowns&Nes s US 2007/01 16831 A1 May 24, 2007 DENTAL COMPOSITION WITH HIGH-POTENCY expanded. Accordingly, it would be desirable to selectively SWEETENER modify the taste characteristics of natural and synthetic high-potency Sweeteners. RELATED APPLICATION DATA 0001. The present application claims priority under 35 SUMMARY OF THE INVENTION U.S.C. S 119 to U.S. Provisional Application No. 60/739, 0005 Generally, this invention addresses the above 302, entitled “Natural High-Potency Sweetener Composi described need by providing a dental composition having tions With Improved Temporal Profile And/Or Flavor Pro improved temporal profile and/or flavor profile and a method file, Methods For Their Formulations, and Uses, filed on for improving the temporal profile and/or flavor profile for Nov. 23, 2005: U.S. Provisional Application No. 60/739, dental compositions. In particular, this invention improves 124, entitled “Synthetic Sweetener Compositions with the temporal profile and/or flavor profile by imparting a Improved Temporal Profile and/or Flavor Profile, Methods more sugar-like temporal profile and/or flavor profile. More for Their Formulation, and Uses, filed on Nov. 23, 2005; particularly, this invention comprises a dental composition U.S. Provisional Application No. 60/805,209, entitled comprising an active dental Substance; at least one high “Natural High-Potency Tabletop Sweetener Compositions potency Sweetener, and at least one Sweet taste improving with Improved Temporal and/or Flavor Profiles, Methods for composition. Their Formulation, and Uses, filed on Jun. 19, 2006; and 0006 Objects and advantages of the invention will be set U.S. Provisional Application No. 60/805,216, entitled forth in part in the following description, or may be obvious “Rebaudioside A Composition and Method for Purifying from the description, or may be learned through practice of Rebaudioside A, filed on Jun. 19, 2006. These applications the invention. Unless otherwise defined, all technical and are hereby incorporated by reference in their entirety. scientific terms and abbreviations used herein have the same meaning as commonly understood by one of ordinary skill FIELD OF THE INVENTION in the art to which this invention pertains. Although methods 0002 The present invention relates generally to a dental and compositions similar or equivalent to those described composition comprising a high-potency Sweetener compo herein can be used in practice of the present invention, sition with improved temporal profile and/or flavor profile. suitable methods and compositions are described without intending that any such methods and compositions limit the BACKGROUND OF THE INVENTION invention herein. 0003 Natural caloric sugars, such as sucrose, fructose, BRIEF DESCRIPTION OF THE DRAWINGS and glucose are utilized heavily in beverage, food, dental, and oral hygienic/cosmetic industries due to their pleasant 0007 FIG. 1 is a powder X-ray diffraction scan of rebau taste. In particular, Sucrose imparts a desirable taste for dioside A polymorph Form 1 on a plot of the scattering consumers. Although Sucrose provides Superior Sweetness intensity versus the scattering angle 20 in accordance with characteristics, it is caloric. While calories are necessary for an embodiment of this invention. proper bodily functions, there is a need in the market to 0008 FIG. 2 is a powder X-ray diffraction scan of rebau provide alternative non-caloric or low-caloric Sweeteners dioside A polymorph Form 2 on a plot of the scattering with Sugar-like taste for consumers with sedentary lifestyles intensity versus the scattering angle 20 in accordance with or those who are calorie conscious. However, in general, an embodiment of this invention. non-caloric or low caloric Sweeteners have associated unde sirable tastes to consumers such as delayed Sweetness onset; 0009 FIG. 3 is a powder X-ray diffraction scan of rebau lingering Sweet aftertaste; bitter taste; metallic taste; astrin dioside A polymorph Form 3A on a plot of the scattering gent taste; cooling taste; licorice-like taste; and/or the like. intensity versus the scattering angle 20 in accordance with an embodiment of this invention. 0004 For example, the sweet tastes of natural and/or synthetic high-potency Sweeteners are slower in onset and 0010 FIG. 4 is a powder X-ray diffraction scan of rebau longer in duration than the Sweet taste produced by Sugar dioside A polymorph Form 3B on a plot of the scattering and thus change the taste balance of a food composition. intensity versus the scattering angle 20 in accordance with Because of these differences, use of a natural high-potency an embodiment of this invention. Sweetener to replace a bulk Sweetener, such as Sugar, in a 0011 FIG. 5 is a powder-X-ray diffraction scan of rebau food or beverage, causes an unbalanced temporal profile dioside A polymorph Form 4 on a plot of the scattering and/or flavor profile. In addition to the difference in temporal intensity versus the scattering angle 20 in accordance with profile, high-potency Sweeteners generally exhibit (i) lower an embodiment of this invention. maximal response than Sugar, (ii) off tastes including bitter, metallic, cooling, astringent, licorice-like taste, etc., and/or DETAILED DESCRIPTION OF THE (iii) Sweetness which diminishes on iterative tasting. It is INVENTION well known to those skilled in the art of food/beverage formulation that changing the Sweetener in a composition 0012 Reference now will be made in detail to the pres requires re-balancing of the flavor and other taste compo ently proffered embodiments of the invention. Each example nents (e.g., acidulants). If the taste profile of natural and is provided by way of explanation of embodiments of the synthetic high-potency Sweeteners could be modified to invention, not limitation of the invention. In fact, it will be impart specific desired taste characteristics to be more apparent to those skilled in the art that various modifications Sugar-like, the type and variety of compositions that may be and variations can be made in the present invention without prepared with that sweetener would be significantly departing from the spirit or scope of the invention. For US 2007/01 16831 A1 May 24, 2007 instance, features illustrated or described as part of one not limited to, water, sodium lauryl sulfate or other sulfates, embodiment, can be used on another embodiment to yield a humectants, enzymes, vitamins, herbs, calcium, flavorings still further embodiment. Thus, it is intended that the present (e.g., mint, bubblegum, cinnamon, lemon, or orange), Sur invention cover Such modifications and variations within the face-active agents, binders, preservatives, gelling agents, pH Scope of the appended claims and their equivalents. modifiers, peroxide activators, stabilizers, coloring agents, 0013 Generally described, embodiments of the present or similar type materials, or combinations thereof invention provide dental compositions comprising at least one natural and/or synthetic high-potency Sweetener, at least 0019. The base material of the dental composition may one Sweet taste improving composition, and an active dental optionally include other artificial or natural Sweeteners, bulk Substance.
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