September 25, 2018 u vol. 115 u no. 39

From the Cover

9714 Social networks and partisan bias E9153 mRNA-based cancer vaccine E9182 Gene therapy and muscular dystrophy 9672 Ion-conducting perovskite materials 9779 Arginine deprivation and tuberculosis

Contents

THIS WEEK IN PNAS 9641 In This Issue Cover image: Pictured is a cliff exposed by glacial retreat. Douglas Guilbeault et al. found that in bipartisan social LETTERS (ONLINE ONLY) networks, liberals’ and conservatives’ interpretations of data on Arctic sea ice E9026 Pitfall of big databases became more accurate and less biased Zhangqiang You, Junhua Hu, Qing Wei, Chunwang Li, Xiaofei Deng, and Zhigang Jiang upon exposure to each other’s opinions E9029 Reply to You et al.: The World Database on Protected Areas is an invaluable in the absence of political imagery. resource for global conservation assessments and planning However, such effects were not Paul R. Elsen, William B. Monahan, and Adina M. Merenlender observed when participants were exposed to each other’s opinions in the presence of political party logos. The OPINION—Leading scientists discuss current issues results suggest that exposure to 9642 Reconsidering bioenergy given the urgency of climate protection opposing views can reduce partisan bias John M. DeCicco and William H. Schlesinger in interpretation of climate data, but only in the absence of political cues. See the article by Guilbeault et al. on pages PROFILE 9714–9719. Image courtesy of Unsplash/ 9646 Profile of Yuval Peres Yiran Ding. Sandeep Ravindran See Inaugural Article on page 9666

COMMENTARIES 9649 More security may actually make us feel less secure Vesla M. Weaver See companion article on page 9181 in issue 37 of volume 115 9652 Building immune tolerance through DNA vaccination Robin J. Parks and Emanuela Gussoni See companion article on page E9182 9655 Ionic gating drives correlated insulator–metal transition Andrew M. Rappe See companion article on page 9672

9658 Death of Mycobacterium tuberculosis by L-arginine starvation Valerie Mizrahi and Digby F. Warner See companion article on page 9779

Free online through the PNAS open access option. PNAS u September 25, 2018 u vol. 115 u no. 39 u iii–vi Downloaded by guest on September 26, 2021 E9153 mRNA vaccination with charge-altering releasable PNAS PLUS transporters elicits human T cell responses 9661 Significance Statements and cures established tumors in mice Brief statements written by the authors about the significance of their Ole A. W. Haabeth, Timothy R. Blake, Colin J. papers. McKinlay, Robert M. Waymouth, Paul A. Wender, and Ronald Levy INAUGURAL ARTICLE 9678 Describing strong correlation with fractional-spin correction in density functional theory 9666 Gravitational allocation on the sphere Neil Qiang Su, Chen Li, and Weitao Yang Nina Holden, Yuval Peres, and Alex Zhai See Profile on page 9646 EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES 9684 Deep learning to represent subgrid processes in PHYSICAL SCIENCES climate models APPLIED MATHEMATICS Stephan Rasp, Michael S. Pritchard, and Pierre Gentine 9666 Gravitational allocation on the sphere Nina Holden, Yuval Peres, and Alex Zhai ENGINEERING 90 See Profile on page 9646 9690 Radioactive ( Y) upconversion nanoparticles conjugated with recombinant targeted toxin 9803 Measurement invariance explains the universal law of for synergistic nanotheranostics of cancer generalization for psychological perception Evgenii L. Guryev, Natalia O. Volodina, Natalia Y. Shilyagina, Steven A. Frank Sergey V. Gudkov, Irina V. Balalaeva, Arthur B. Volovetskiy, Alexander V. Lyubeshkin, Alexey V. Sen’, Sergey A. Ermilov, APPLIED PHYSICAL SCIENCES Vladimir A. Vodeneev, Rem V. Petrov, Andrei V. Zvyagin, E9031 Topological localization in out-of-equilibrium Zhores I. Alferov, and Sergey M. Deyev dissipative systems Kinjal Dasbiswas, Kranthi K. Mandadapu, SUSTAINABILITY SCIENCE and Suriyanarayanan Vaikuntanathan 9720 High nitrous oxide fluxes from rice indicate the need 9672 Strongly correlated perovskite lithium ion shuttles to manage water for both long- and short-term Yifei Sun, Michele Kotiuga, Dawgen Lim, Badri Narayanan, climate impacts Mathew Cherukara, Zhen Zhang, Yongqi Dong, Ronghui Kritee Kritee, Drishya Nair, Daniel Zavala-Araiza, Jeremy Kou, Cheng-Jun Sun, Qiyang Lu, Iradwikanari Waluyo, Proville, Joseph Rudek, Tapan K. Adhya, Terrance Loecke, Adrian Hunt, Hidekazu Tanaka, Azusa N. Hattori, Sampath Tashina Esteves, Shalini Balireddygari, Obulapathi Dava, Gamage, Yohannes Abate, Vilas G. Pol, Hua Zhou, Karthik Ram, Abhilash S. R., Murugan Madasamy, Subramanian K. R. S. Sankaranarayanan, Bilge Yildiz, Karin M. Ramakrishna V. Dokka, Daniel Anandaraj, D. Athiyaman, Rabe, and Shriram Ramanathan Malla Reddy, Richie Ahuja, and Steven P. Hamburg See Commentary on page 9655

BIOPHYSICS AND COMPUTATIONAL SOCIAL SCIENCES E9201 Structural basis for murine norovirus engagement of ECONOMIC SCIENCES bile acids and the CD300lf receptor Christopher A. Nelson, Craig B. Wilen, Ya-Nan Dai, Robert C. 9696 Predicting human behavior toward members of Orchard, Arthur S. Kim, Roderick A. Stegeman, Leon L. Hsieh, different social groups Thomas J. Smith, Herbert W. Virgin, and Daved H. Fremont Adrianna C. Jenkins, Pierre Karashchuk, Lusha Zhu, and Ming Hsu E9247 Universal method for robust detection of circadian state from gene expression PSYCHOLOGICAL AND COGNITIVE SCIENCES Rosemary Braun, William L. Kath, Marta Iwanaszko, Elzbieta Kula-Eversole, Sabra M. Abbott, Kathryn J. Reid, Phyllis C. Zee, E9067 The culture of social comparison and Ravi Allada Matthew Baldwin and Thomas Mussweiler 9738 Structural conditions on complex networks for the 9702 Cross-cultural invariances in the architecture Michaelis–Menten input–output response of shame Felix Wong, Annwesha Dutta, Debashish Chowdhury, Daniel Sznycer, Dimitris Xygalatas, Elizabeth Agey, Sarah and Jeremy Gunawardena Alami, Xiao-Fen An, Kristina I. Ananyeva, Quentin D. Atkinson, Bernardo R. Broitman, Thomas J. Conte, Carola Flores, Shintaro Fukushima, Hidefumi Hitokoto, Alexander N. E9041 Membrane-wrapped nanoparticles probe divergent Kharitonov, Charity N. Onyishi, Ike E. Onyishi, Pedro P. roles of GM3 and phosphatidylserine in lipid- Romero, Joshua M. Schrock, J. Josh Snodgrass, Lawrence S. mediated viral entry pathways Sugiyama, Kosuke Takemura, Cathryn Townsend, Jin-Ying Zhuang, C. Athena Aktipis, Lee Cronk, Leda Cosmides, Fangda Xu, Asanga Bandara, Hisashi Akiyama, Behnaz and John Tooby Eshaghi, David Stelter, Tom Keyes, John E. Straub, Suryaram Gummuluru, and Bjo¨rn M. Reinhard 9708 Language switching decomposed through MEG and E9051 Macrocycle ring deformation as the secondary design evidence from bimodal bilinguals principle for light-harvesting complexes Esti Blanco-Elorrieta, Karen Emmorey, and Liina Pylkka¨nen Luca De Vico, Andre´ Anda, Vladimir Al. Osipov, Anders Ø. Madsen, and Thorsten Hansen SOCIAL SCIENCES E9058 Pendular alignment and strong chemical binding are 9714 Social learning and partisan bias in the interpretation induced in helium dimer molecules by intense laser fields of climate trends Qi Wei, Sabre Kais, Tomokazu Yasuike, and Dudley Herschbach Douglas Guilbeault, Joshua Becker, and Damon Centola

iv u www.pnas.org Contents Downloaded by guest on September 26, 2021 E9125 Mutually inhibitory Ras-PI(3,4)P feedback loops BIOLOGICAL SCIENCES 2 mediate cell migration AGRICULTURAL SCIENCES Xiaoguang Li, Marc Edwards, Kristen F. Swaney, Nilmani Singh, Sayak Bhattacharya, Jane Borleis, Yu Long, Pablo A. Iglesias, 9720 High nitrous oxide fluxes from rice indicate the need Jie Chen, and Peter N. Devreotes to manage water for both long- and short-term climate impacts 9750 CAMSAP3 maintains neuronal polarity through Kritee Kritee, Drishya Nair, Daniel Zavala-Araiza, Jeremy regulation of microtubule stability Proville, Joseph Rudek, Tapan K. Adhya, Terrance Loecke, Varisa Pongrakhananon, Hiroko Saito, Sylvain Hiver, Tashina Esteves, Shalini Balireddygari, Obulapathi Dava, Takaya Abe, Go Shioi, Wenxiang Meng, Karthik Ram, Abhilash S. R., Murugan Madasamy, and Masatoshi Takeichi Ramakrishna V. Dokka, Daniel Anandaraj, D. Athiyaman, Malla Reddy, Richie Ahuja, and Steven P. Hamburg DEVELOPMENTAL BIOLOGY E9135 Bighead is a Wnt antagonist secreted by the Xenopus APPLIED BIOLOGICAL SCIENCES Spemann organizer that promotes Lrp6 endocytosis 9726 Improving nanopore read accuracy with the R2C2 Yi Ding, Gabriele Colozza, Eric A. Sosa, Yuki method enables the sequencing of highly Moriyama, Samantha Rundle, Lukasz Salwinski, multiplexed full-length single-cell cDNA and Edward M. De Robertis Roger Volden, Theron Palmer, Ashley Byrne, Charles Cole, Robert J. Schmitz, Richard E. Green, and Christopher Vollmers 9702 Cross-cultural invariances in the architecture BIOCHEMISTRY of shame E9075 Structure-specific DNA replication-fork recognition Daniel Sznycer, Dimitris Xygalatas, Elizabeth Agey, Sarah directs helicase and replication restart activities Alami, Xiao-Fen An, Kristina I. Ananyeva, Quentin D. Atkinson, of the PriA helicase Bernardo R. Broitman, Thomas J. Conte, Carola Flores, Tricia A. Windgassen, Maxime Leroux, Kenneth A. Satyshur, Shintaro Fukushima, Hidefumi Hitokoto, Alexander N. Steven J. Sandler, and James L. Keck Kharitonov, Charity N. Onyishi, Ike E. Onyishi, Pedro P. E9085 Function and crystal structure of the dimeric P-loop Romero, Joshua M. Schrock, J. Josh Snodgrass, Lawrence S. Sugiyama, Kosuke Takemura, Cathryn Townsend, Jin-Ying ATPase CFD1 coordinating an exposed [4Fe-4S] Zhuang, C. Athena Aktipis, Lee Cronk, Leda Cosmides, cluster for transfer to apoproteins and John Tooby Oliver Stehling, Jae-Hun Jeoung, Sven A. Freibert, Viktoria D. Paul, Sebastian Ba¨nfer, Brigitte Niggemeyer, Ralf Ro¨sser, 9756 Deceptive signals and behaviors of a cleptoparasitic Holger Dobbek, and Roland Lill beetle show local adaptation to different host bee species 9732 Intermediate step of cohesin’s ATPase cycle allows Leslie Saul-Gershenz, Jocelyn G. Millar, J. Steven McElfresh, cohesin to entrap DNA and Neal M. Williams Gamze O¨ .C¸ amdere, Kristian K. Carlborg, and Douglas Koshland 9761 Genetic divergence and the number of hybridizing BIOPHYSICS AND COMPUTATIONAL BIOLOGY species affect the path to homoploid speciation E9095 Structural basis for activation of voltage sensor Aaron A. Comeault and Daniel R. Matute domains in an ion channel TPC1 Alexander F. Kintzer, Evan M. Green, Pawel K. Dominik, 9767 Cellular hysteresis as a principle to maximize the Michael Bridges, Jean-Paul Armache, Dawid Deneka, efficacy of antibiotic therapy Sangwoo S. Kim, Wayne Hubbell, Anthony A. Kossiakoff, Yifan Roderich Roemhild, Chaitanya S. Gokhale, Philipp Dirksen, Cheng, and Robert M. Stroud Christopher Blake, Philip Rosenstiel, Arne Traulsen, Dan I. Andersson, and Hinrich Schulenburg 9738 Structural conditions on complex networks for the Michaelis–Menten input–output response Felix Wong, Annwesha Dutta, Debashish Chowdhury, GENETICS and Jeremy Gunawardena E9145 Partial maintenance of organ-specific epigenetic 9744 Systematic mapping of free energy landscapes of marks during asexual reproduction leads to a growing filamin domain during biosynthesis heritable phenotypic variation Christopher A. Waudby, Tomasz Wlodarski, Maria-Evangelia Anjar Wibowo, Claude Becker, Julius Durr, Jonathan Price, Stijn Karyadi, Anaı¨s M. E. Cassaignau, Sammy H. S. Chan, Anne S. Spaepen, Sally Hilton, Hadi Putra, Ranjith Papareddy, Quentin Wentink, Julian M. Schmidt-Engler, Carlo Camilloni, Michele Saintain, Sarah Harvey, Gary D. Bending, Paul Schulze-Lefert, Vendruscolo, Lisa D. Cabrita, and John Christodoulou Detlef Weigel, and Jose Gutierrez-Marcos

CELL BIOLOGY IMMUNOLOGY AND INFLAMMATION β E9105 Autonomous conformational regulation of 3 integrin E9153 mRNA vaccination with charge-altering releasable and the conformation-dependent property of transporters elicits human T cell responses HPA-1a alloantibodies and cures established tumors in mice Aye Myat Myat Thinn, Zhengli Wang, Dongwen Zhou, Yan Ole A. W. Haabeth, Timothy R. Blake, Colin J. Zhao, Brian R. Curtis, and Jieqing Zhu McKinlay, Robert M. Waymouth, Paul A. Wender, E9115 LRRK2 and its substrate Rab GTPases are sequentially and Ronald Levy targeted onto stressed lysosomes and maintain E9162 Interferon stimulation creates chromatin marks and their homeostasis establishes transcriptional memory Tomoya Eguchi, Tomoki Kuwahara, Maria Sakurai, Tadayuki Rui Kamada, Wenjing Yang, Yubo Zhang, Mira C. Patel, Yanqin Komori, Tetta Fujimoto, Genta Ito, Shin-ichiro Yoshimura, Yang, Ryota Ouda, Anup Dey, Yoshiyuki Wakabayashi, Akihiro Harada, Mitsunori Fukuda, Masato Koike, Kazuyasu Sakaguchi, Takashi Fujita, Tomohiko Tamura, Jun and Takeshi Iwatsubo Zhu, and Keiko Ozato

Contents PNAS u September 25, 2018 u vol. 115 u no. 39 u v Downloaded by guest on September 26, 2021 E9172 Deconvolution of pro- and antiviral genomic responses NEUROSCIENCE in Zika virus-infected and bystander macrophages E9220 Cortical circuit activity underlying sleep slow Aaron F. Carlin, Edward A. Vizcarra, Emilie Branche, Karla M. oscillations and spindles Viramontes, Lester Suarez-Amaran, Klaus Ley, Sven Heinz, Niels Niethard, Hong-Viet V. Ngo, Ingrid Ehrlich, Christopher Benner, Sujan Shresta, and Christopher K. Glass and Jan Born 9773 Functional characterization of reappearing E9230 Tissue plasminogen activator promotes white matter B cells after anti-CD20 treatment of CNS integrity and functional recovery in a murine autoimmune disease model of traumatic brain injury Darius Ha¨usler, Silke Ha¨usser-Kinzel, Linda Feldmann, Sebastian Yuguo Xia, Hongjian Pu, Rehana K. Leak, Yejie Shi, Hongfeng Torke, Gildas Lepennetier, Claude C. A. Bernard, Scott S. Zamvil, Mu, Xiaoming Hu, Zhengyu Lu, Lesley M. Foley, T. Kevin Wolfgang Bru¨ck, Klaus Lehmann-Horn, and Martin S. Weber Hitchens, C. Edward Dixon, Michael V. L. Bennett, and Jun Chen MEDICAL SCIENCES E9182 Engineered DNA plasmid reduces immunity to PLANT BIOLOGY dystrophin while improving muscle force in a model E9239 AP2 transcription factor CBX1 with a specific function of gene therapy of Duchenne dystrophy in symbiotic exchange of nutrients in mycorrhizal Peggy P. Ho, Lauren J. Lahey, Foteini Mourkioti, Peggy E. Kraft, Lotus japonicus Antonio Filareto, Moritz Brandt, Klas E. G. Magnusson, Eric E. Li Xue, Lompong Klinnawee, Yue Zhou, Georgios Finn, Jeffrey S. Chamberlain, William H. Robinson, Helen M. Saridis, Vinod Vijayakumar, Mathias Brands, Blau, and Lawrence Steinman Peter Do¨rmann, Tamara Gigolashvili, Franziska Turck, See Commentary on page 9652 and Marcel Bucher E9192 Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death PSYCHOLOGICAL AND COGNITIVE SCIENCES Ricard Garcia-Carbonell, Jerry Wong, Ju Youn Kim, Lisa Abernathy 9696 Predicting human behavior toward members of Close, Brigid S. Boland, Thomas L. Wong, Philip A. Harris, different social groups SamuelB.Ho,SoumitaDas,PeterB.Ernst,RomanSasik,WilliamJ. Adrianna C. Jenkins, Pierre Karashchuk, Lusha Zhu, Sandborn, John Bertin, Pete J. Gough, John T. Chang, Michelle and Ming Hsu Kelliher, David Boone, Monica Guma, and Michael Karin 9803 Measurement invariance explains the universal law of MICROBIOLOGY generalization for psychological perception Steven A. Frank E9041 Membrane-wrapped nanoparticles probe divergent roles of GM3 and phosphatidylserine in lipid- mediated viral entry pathways SYSTEMS BIOLOGY Fangda Xu, Asanga Bandara, Hisashi Akiyama, Behnaz E9247 Universal method for robust detection of circadian Eshaghi, David Stelter, Tom Keyes, John E. Straub, Suryaram state from gene expression Gummuluru, and Bjo¨rn M. Reinhard Rosemary Braun, William L. Kath, Marta Iwanaszko, Elzbieta E9201 Structural basis for murine norovirus engagement of Kula-Eversole, Sabra M. Abbott, Kathryn J. Reid, Phyllis C. Zee, bile acids and the CD300lf receptor and Ravi Allada Christopher A. Nelson, Craig B. Wilen, Ya-Nan Dai, Robert C. Orchard, Arthur S. Kim, Roderick A. Stegeman, Leon L. Hsieh, Thomas J. Smith, Herbert W. Virgin, and Daved H. Fremont CORRECTIONS (ONLINE ONLY) E9211 Homologous recombination is an intrinsic defense against antiviral RNA interference LETTER Lauren C. Aguado, Tristan X. Jordan, Emily Hsieh, Daniel E9257 Psychological targeting Blanco-Melo, John Heard, Maryline Panis, Marco Vignuzzi, Byron Sharp, Nick Danenberg, and Steven Bellman and Benjamin R. tenOever 9779 Arginine-deprivation–induced oxidative damage CHEMISTRY, BIOPHYSICS AND COMPUTATIONAL BIOLOGY sterilizes Mycobacterium tuberculosis E9258 On the importance of accounting for nuclear Sangeeta Tiwari, Andries J. van Tonder, Catherine Vilche`ze, quantum effects in ab initio calibrated force Vitor Mendes, Sherine E. Thomas, Adel Malek, Bing Chen, fields in biological simulations Mei Chen, John Kim, Tom L. Blundell, Julian Parkhill, Brian Leonid Pereyaslavets, Igor Kurnikov, Ganesh Kamath, Weinrick, Michael Berney, and William R. Jacobs Jr. Oleg Butin, Alexey Illarionov, Igor Leontyev, Michael See Commentary on page 9658 Olevanov, Michael Levitt, Roger D. Kornberg, 9785 A plant-responsive bacterial-signaling system senses and Boris Fain an ethanolamine derivative Bruna G. Coutinho, Emily Mevers, Amy L. Schaefer, BIOPHYSICS AND COMPUTATIONAL BIOLOGY Dale A. Pelletier, Caroline S. Harwood, Jon Clardy, E9259 Tethered multifluorophore motion reveals and E. Peter Greenberg equilibrium transition kinetics of single 9791 Cell-to-cell bacterial interactions promoted by drier DNA double helices conditions on soil surfaces Matthias Schickinger, Martin Zacharias, and Hendrik Dietz Robin Tecon, Ali Ebrahimi, Hannah Kleyer, Shai Erev Levi, and Dani Or DEVELOPMENTAL BIOLOGY 9797 Superoxide dismutase activity confers (p)ppGpp- E9260 Drosophila E-cadherin is required for the mediated antibiotic tolerance to stationary-phase maintenance of ring canals anchoring to Pseudomonas aeruginosa mechanically withstand tissue growth Dorival Martins, Geoffrey McKay, Gowthami Sampathkumar, Nicolas Loyer, Irina Kolotuev, Mathieu Pinot, Malika Khakimova, Ann M. English, and Dao Nguyen and Roland Le Borgne

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