sign in sign up
<<
Home , Sodium azide

Repligen Cassette

Sodium /Glycerin Solution Safety Data Sheet

1. PRODUCT AND COMPANY IDENTIFICATION None. 1.1. Product Identifier 5.2. Special Hazards arising from the Substance or Mixture Cassette Preservative ■ Fire hazard: Azide/Glycerin Solution When heated to decomposition, emits toxic fumes. 1.2. Recommended Use of Substance/Preparation ■ Explosion hazard: Filtration (cassette) Device Preservative None known. 1.3. Supplier of Safety Data Sheet 5.3. Advice for Firefighters Repligen Corporation ■ Protection during firefighting: 910 Boston Turnpike Road, Unit #5 Firefighters should wear full protective gear. Shrewsbury, MA 01545 6. ACCIDENTAL RELEASE MEASURES T 508.845.6400 / F 508.845.3030 6.1. Personal Precautions, Protective Equipment and Emergency Procedures 1.4. Emergency and Contact Telephone Number(s) ■ For non-emergency personnel: ChemTel No additional information available. 1.800.255.3924 (US, Canada, Puerto Rico, US Virgin Islands) ■ For emergency responders: +01.813.248.0585 (International) No additional information available. MIS0007989 (Repligen Contract Number) 6.2. Environmental Precautions 2. HAZARDS IDENTIFICATION Avoid release to the environment. 2.1. GHS-US Classification 6.3. Methods and Material for Containment and Cleaning Up Not regulated as a GHS hazardous substance. ■ For containment: 2.2. GHS-US Label Elements Stop the flow of material, if this is without risk. ■ Hazards Pictograms (GHS-US) ■ Methods for clean up: None required. Confine spill and soak up with absorbent. Place in an approved ■ Signal Word (GHS-US) container and dispose in accordance with local, state and federal None required. regulations. ■ Hazard Statements (GHS-US) 6.4. Reference to Other Sections None required. No additional information available. ■ Precautionary Statement 7. HANDLING & STORAGE None required. 7.1. Precautions for Safe Handling 2.3. Other Hazards / Not Otherwise Classified Avoid breathing vapors. No additional information available. 7.2. Conditions for Safe Storage, including any incompatibilities 2.4. Unknown Acute Toxicity (GHS-US) Store in dry, cool, well-ventilated area. Keep container tightly closed. No data available. 7.3. Specific end use(s) 3.0 INGREDIENTS / COMPOSITION INFORMATION Filtration (cassette) Device Preservative Name CAS Number % 8. EXPOSURE CONTROLS / PERSONAL PROTECTION 7732-18-5 77.89 - 81.91 8.1. Control Parameters Glycerin 56-81-5 18 - 22 Sodium Azide (26628-22-8) Sodium Azide 26628-22-8 0.09 - 0.11 USA ACGIH ACGIH Ceiling (mg/m³) 0.29 mg/m³ 4. FIRST AID MEASURES USA ACGIH ACGIH Ceiling (ppm) 0.11 ppm 4.1. Description of First Aid Measures Glycerin (56-81-5) ■ First-aid measures after inhalation: USA OSHA OSHA PEL (TWA) (mg/ m³) 5 mg/m³ Remove person to fresh air. If not breathing, administer CPR or artificial

respiration. Get immediate medical attention. 8.2. Exposure controls

■ First-aid measures after skin contact: ■ Appropriate engineering controls: If skin reddening or irritation develops, seek medical attention. Local exhaust and general ventilation must be adequate to meet ■ First-aid measures after eye contact: exposure standards. Flush with plenty of water for at least 15 minutes. Seek medical advice ■ Hand protection: if irritation develops or persists. Use impervious gloves such as neoprene, nitrile, or rubber for hand ■ First-aid measures after ingestion: protection. If the material is swallowed, get immediate medical attention or advice. ■ Eye protection: DO NOT induce vomiting unless directed to do so by medical personnel. Chemical goggles or safety glasses. 4.2. Most Important Symptoms and Effects, both acute and delayed ■ Skin and body protection: ■ Symptoms / injuries after inhalation: Wear suitable working clothes. May cause respiratory irritation. ■ Respiratory protection: ■ Symptoms / injuries after skin contact: If airborne concentrations are above the applicable exposure limits, use Frequent or prolonged contact may irritate the skin. NIOSH approved respiratory protection. ■ Symptoms / injuries after eye contact: 9. PHYSICAL AND CHEMICAL PROPERTIES May cause irritation. 9.1. Information on Basic Physical and Chemical Properties ■ Symptoms / injuries after ingestion:  Physical state : Liquid Harmful if swallowed.  Color : White 4.3. Immediate Medical Attention and Special Treatment  Odor : Odorless No additional information available.  Odor threshold : No data available 5. FIREFIGHTING MEASURES  pH : No data available 5.1. Extinguishing Media  Relative evaporation rate (butylacetate=1) : No data available ■ Suitable extinguishing media:  : 18 °C Dry chemical, foam, carbon dioxide.  Freezing point : No data available ■ Unsuitable extinguishing media:  Boiling point : 171 °C

IF.SD1-POP.1034 R2 EN (English) APPROVED 20 DEC 2018 TangenX™ PRO Cassette Preservative - Sodium Azide/Glycerin Solution SAFETY DATA SHEET

 Flash point : 390 °C Glycerin (56-81-5)  Self ignition temperature : No data available BCF fish 1 (no bioaccumulation)  Decomposition temperature : No data available Log Pow -1.76  Flammability (solid, gas) : No data available 12.4. Mobility in Soil  Vapor pressure : No data available No additional information available.  Relative vapor density at 20 °C : No data available 12.5. Other Adverse Effects  Specific gravity : 1.2607 No additional information available.  : Complete  Log Pow : No data available 13. DISPOSAL CONSIDERATIONS  Log Kow : No data available 13.1. Waste Treatment Methods  Viscosity, kinematic : No data available ■ Waste disposal recommendations:  Viscosity, dynamic : No data available Dispose of contents/container in accordance with local/regional/  properties : No data available national/international regulations.  Oxidising properties : No data available 14. TRANSPORT INFORMATION  Explosive limits : No data available  In accordance with DOT. 9.2. Other Information  Not regulated for transportation as a dangerous good / hazardous No additional information available. material. 10. STABILITY AND REACTIVITY 15. REGULATORY INFORMATION 10.1. Reactivity 15.1. US Federal Regulations No additional information available. Water (7732-18-5) 10.2. Chemical Stability Listed on the United States TSCA (Toxic Substances Control Act) inventory The product is stable at normal handling and storage conditions.

10.3. Possibility of Hazardous Reactions Sodium Azide (26628-22-8) Will not occur. Listed on the United States TSCA (Toxic Substances Control Act) inventory 10.4. Conditions to Avoid Listed on SARA Section 302 (Specific toxic chemical listings) None. Listed on SARA Section 313 (Specific toxic chemical listings) 10.5. Incompatible Materials SARA Section 302 - Threshold 500 / This material is a reactive solid. The TPQ Strong acids. Strong bases. Strong oxidizing agents. does not default to 10000 pounds for non-powder, Planning Quantity (TPQ) non-molten, non-solution form. 10.6. Hazardous Decomposition Products SARA Section 313 - Emission Oxides of carbon. 1.0% Reporting 11. TOXICOLOGICAL INFORMATION 11.1. Information on Toxicological Effects Glycerin (56-81-5)  Acute toxicity Harmful if swallowed Listed on the United States TSCA (Toxic Substances Control Act) inventory Y2 - Y2 / Indicates an exempt polymer that is a Cassette Preservative - Sodium Azide/Glycerin Solution EPA TSCA Regulatory Flag polyester and is made only from reactants included in ATE (oral) 500.000 mg/kg bodyweight a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. Sodium Azide (26628-22-8) 15.2. US State Regulations LD50 oral rat 27 mg/kg ■ Sodium Azide (26628-22-8)

Glycerin (56-81-5) U.S. - Massachusetts - Right To Know List LD50 dermal rabbit > 10 g/kg U.S. - Minnesota - Hazardous Substance List LC50 inhalation rat (mg/l) > 570 mg/m³ (Exposure time: 1 h) U.S. - New Jersey - Right to Know Hazardous Substance List ATE (oral) 12600.000 mg/kg U.S. - Pennsylvania - RTK (Right to Know) List  Skin corrosion/irritation : Not classified ■ Glycerin (56-81-5) U.S. - Massachusetts - Right To Know List  Serious eye damage/irritation : Not classified U.S. - Minnesota - Hazardous Substance List  Respiratory or skin sensitization : Not classified U.S. - New Jersey - Right to Know Hazardous Substance List  Germ cell mutagenicity : Not classified U.S. - Pennsylvania - RTK (Right to Know) List  Carcinogenicity : Not classified  Reproductive toxicity : Not classified 16. OTHER INFORMATION  Specific target organ toxicity : Not classified  No additional information available. (single exposure)  22-Feb-2016 Safety data sheet was updated. Revised GHS  Specific target organ toxicity : Not classified classification and DOT transport information. (repeated exposure)  This information is based on our current knowledge and is intended  Aspiration hazard : Not classified to describe the product for the purposes of health, safety and 12. ECOLOGICAL INFORMATION environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product. 12.1. Toxicity  TangenX™ PRO is a Repligen trademark registered in the USA.

Sodium Azide (26628-22-8) 0.8 mg/l (Exposure time: 96 h - LC50 fishes 1 Repligen Corporation Species: Oncorhynchus mykiss) 111 Locke Drive 0.7 mg/l (Exposure time: 96 h - Marlborough MA, 01752 USA LC50 fish 2 Species: Lepomis macrochirus) Glycerin (56-81-5) 508.845.6400 (phone) 508.845.3030 (fax) 51 - 57 ml/l (Exposure time: 96 h - LC50 fishes 1 www.repligen.com/tangenx (website) Species: Oncorhynchus mykiss [static]) 508.845.1621 (order fax)

12.2. Persistence and Degradability [email protected] (email) No additional information available.

12.3. Bioaccumulative Potential

IF.SD1-POP.1034 R2 EN (English) APPROVED 20 DEC 2018