TECHNICAL BULLETIN

Barcroft™ Magnesium Hydroxide Powders

SPI Pharma’s line of magnesium hydroxide powders is available worldwide and These spray dried powders provides the consistent quality required for pharmaceutical use. These powders are specifically designed for are used in wet granulation and direct compression tableting and suspension use in antacid tablets. applications. The products listed are typical of the SPI Pharma magnesium Resuspendible powders are hydroxide powder product line. Products are customized upon request. used for Milk of Magnesia Typical products and properties: (MOM) and antacid suspensions. They are also used in the production of ™ Barcroft Assay Surface Area Comments Product (as Al(OH)3) salts of weak acids, such as magnesium citrate. 5100CG 95-100% 50 m2/g USP, EP, low lead (<125ppb) 5200M 95-100% 65 m2/g USP, EP, resuspendible • meet USP/EP code 5300D 95-100% 45 m2/g USP dense powder (0.7 g/ml) • available in low and high surface area to meet formulation requirements 5100CG is primarily used in wet granulated antacid and laxative tablets. It is free flowing and blends very well with other ingredients. It is low lead (<125 ppb) • products produce very and can be used in antacids that must meet USA’s California Proposition 65. consistent re-hydrated 5200M is a medium-density product specifically designed for rehydration from pourable gels (MOM) the powdered form to produce a smooth, viscous, nonseparating suspension. This is required for milk of magnesia (MOM) laxative systems. Barcroft™ 5200M • spray dried to control is cost-effective for shipment anywhere in the world since it eliminates the cost particle size and density of shipping water. • low lead product meets 5300D is a denser powder that conforms to USP standards. These products are USA’s California Proposition used in wet granulated laxatives and antacids. Magnesium hydroxide powder is 65 standards <125ppb also used in the production of magnesium citrate and magnesium gluconate. Selecting the right Barcroft™ grade of magnesium powder allows the formulator to make a high-quality antacid at a competitive price. The SPI Pharma technical staff can assist in choosing the product that will run the most efficiently in your production facility. TECHNICAL BULLETIN

Formulating Success Through Innovation

Americas Europe/Middle East/Africa Asia/Pacific Australia Distribution Company www.spipharma.com SPI Pharma, Inc. SPI Pharma SAS SPI Pharma, Inc. – India Branch Anzchem, P/L Rockwood Office Park Les Jardins de la Duranne 21 B, Veerasandra Industrial Area Mills Waterfront Estate 503 Carr Rd., Suite 210 Bat C, 510 rue Rene Descartes Hosur Road, Bangalore – 560100 19/52 Holker Street Wilmington, DE 19809 13290 Aix en Provence Karnataka, India Silverwater, NSW 2128 Tel: 302-576-8554 Les Milles, France Tel: 91 8110 669100 Tel: 61294752200 800-789-9755 Tel: 33491963610 Fax: 91 8110 669150 Fax:61294752211 TB107-MagHydroxPwd Ext. 8554 Fax:33442124693 Sales: 91 8110 669104 8-09 Fax: 302-576-8567