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United for global health 2017-2018 Report The Institut Pasteur International Network Table of contents KEY FIGURES 01 The Institut Pasteur International Network, key figures 05 Missions and organization of the Institut Pasteur International Network 06 Development of the Network: a cross-functional priority in the new Institut Pasteur Strategic Plan in 07 The Pasteur International Network association 08 A shared scientific strategy to support the Network’s global health ambitions 25 10 Highlights 2017 32 countries 14 Highlights 2018 member institutes 18 National and international technical expertise 20 PREVENT across 22 A one health approach for effectively detecting vector-borne diseases 24 Organizing monitoring and early warning systems 5 26 Concrete actions: the first Institut Pasteur de Guinée laboratory continents 28 A better understanding of epidemics: the 2017 outbreak of pneumonic plague in Madagascar 30 ALERT 32 The Institut Pasteur International Network against resistance 34 Circumventing viral disease vector insecticide resistance 36 Understanding and fighting pediatric antibiotic resistance 38 PROTECT 40 Essential support for laboratories monitoring pathogens 116 25 42 Contributing to a global vaccination strategy to eliminate rabies by 2030 scientists and students benefiting from international courses organized(1) 44 Leptospirosis: a worrying neglected disease funding of international grants(1) (see pages 52-53) 46 Fighting leishmaniasis, a global scourge (see pages 52-53) 48 Chronic malnutrition in children: a new microbial signature in the gut 50 DEVELOP 52 Training human resources and supporting scientific careers 54 4-year research groups (G4) for developing innovative projects 56 International Joint Research Units to strengthen partnerships 57 Scientific platforms for sharing resources 5 2 60 Partnerships: an essential component 4-year research groups currently running(1) International Joint Research Units created(1) Network Directors and Scientific Directors (see pages 54-55) (see page 56) THANKS A SCIENTIFIC NETWORK We would like to thank all the employees working in the Institut Pasteur International Network, particularly those who accepted to appear in and/or contribute to this report. We also thank the members of the Institut Pasteur Department of International Affairs for their daily commitment, as well as Marc Jouan, 4,580 1,200 International Vice-President from 2014 to 2018, who joined the Institut Pasteur de Nouvelle-Calédonie in January 2019. The average number of Web of Science The number of articles uploaded to HAL- Particular thanks go to Évelyne Malanchère for her commitment, throughout her career, to welcoming foreign delegations, articles published by Network members each RIIP(2), an open platform for archiving and and Olivier Rescanière, International Communications Manager until 2018. year, either individually or in collaboration(1). accessing scientific publications(1). We express our sincere gratitude to all the Institut Pasteur teams in Paris for their assistance and cooperation, and all the partners and institutions whose constant support contributes to the development of cooperation programs within the Network to provide valuable benefits for public health. 1 Data for 2017-2018. 2 Hyper articles online (HAL). 1 The Institut Pasteur International Network Comprising 32 members, the Institut Pasteur International Network is active on five continents. Leveraging its vast scientific and human community, the Institut Pasteur International Network takes part in national and international research, public health and education programs. ● SAINT PETERSBURG AMERICAS EUROPE Brazil Belgium LILLE ●● BRUSSELS PARIS Fiocruz Sciensano LAVAL ● ● https://portal.fiocruz.br www.sciensano.be ● SOFIA Canada Bulgaria ● ROME ● TEHRAN Armand-Frappier Stephan Angeloff Institute ● ATHENS Santé Biotechnologie of Microbiology ● ● TUNIS ALGIERS ● SEOUL Research center www.microbio.bas.bg ● www.iaf.inrs.ca France CASABLANCA France Institut Pasteur (Paris) ● SHANGHAI Institut Pasteur www.pasteur.fr de la Guadeloupe Institut Pasteur de Lille HONG KONG http://web.pasteur-guadeloupe.fr www.pasteur-lille.fr HANOI ● ● Institut Pasteur Greece POINTE-À-PITRE VIENTIANE ● ● ● DAKAR de la Guyane Hellenic Pasteur Institute ● NIAMEY ● NHA TRANG www.pasteur-cayenne.fr www.pasteur.gr CONAKRY PHNOM PENH ●● HO CHI MINH CITY Uruguay Italy ● CAYENNE ● Institut Pasteur Institut Pasteur in Italy – ABIDJAN ● de Montevideo Cenci Bolognetti Foundation YAOUNDÉ ● ● BANGUI www.pasteur.edu.uy/en/home www.istitutopasteur.it Russia Institut Pasteur in Saint-Petersburg AFRICA www.pasteurorg.ru Cameroon RIO DE JANEIRO ● Pasteur Center ● ANTANARIVO in Cameroon www.pasteur-yaounde.org NOUMEA Ivory Coast NORTH AFRICA-IRAN ● Institut Pasteur Algeria MONTEVIDEO ● de Côte d’Ivoire Institut Pasteur d’Algérie www.pasteur.ci www.pasteur.dz Guinea Iran Institut Pasteur de Guinée Institut Pasteur in Iran www.pasteur-guinee.org http://en.pasteur.ac.ir/ Madagascar Morocco ASIA-PACIFIC France Institut Pasteur Institut Pasteur du Maroc Cambodia Institut Pasteur de Nouvelle-Calédonie de Madagascar www.pasteur.ma Institut Pasteur du Cambodge www.institutpasteur.nc www.pasteur.mg Tunisia www.pasteur-kh.org Laos Niger Institut Pasteur de Tunis China Institut Pasteur du Laos CERMES www.pasteur.tn Honk Kong University-Pasteur Research Pole www.pasteur.la www.cermes.net www.hkupasteur.hku.hk Vietnam Central African Republic Institut Pasteur of Shanghai – National Institute of Hygiene Epidemiology (Hanoi) Institut Pasteur de Bangui Chinese Academy of Sciences https://nihe.org.vn www.pasteur-bangui.org www.shanghaipasteur.cas.cn Institut Pasteur in Ho Chi Minh City Senegal Korea www.pasteurhcm.gov.vn Institut Pasteur de Dakar Institut Pasteur Korea Institut Pasteur in Nha Trang www.pasteur.sn www.ip-korea.org http://pasteur-nhatrang.org.vn/ 2 3 Stewart Cole Missions and organization President of the Institut Pasteur OF THE INSTITUT PASTEUR INTERNATIONAL NETWORK The development of the Institut Pasteur “International Network is one of my priorities. The 2019-2023 Strategic Plan is a clear reflection of this. The scientific collaborations the Institut Pasteur conducts with The Institut Pasteur Department of International Affairs will its 32 International Network partners provide a concrete continue its efforts to strengthen the competitiveness and response to global health challenges. Together, they have visibility of the Institut Pasteur International Network. The history been able to develop the scientific synergies that are key that Pasteur institutes share commits us to advancing further, to leveraging advances made in fundamental research for building on high-quality research, training opportunities and the the good of public health. provision of public health, particularly to vulnerable populations. Active in 25 countries across The mission of the Institut Pasteur International Network is to contribute to the With the support of the Institut Pasteur, the Network has been Through a collaborative approach in line with the Network’s 5 continents, the Institut improvement of human health, in particular relating to infections, through: able to take action against the recent health crises (Ebola, Zika) scientific strategy, approved by the Council of Directors in Pasteur International that have seriously affected different continents. September 2017, the Network will develop major international biomedical research; I also wish to strengthen the attractiveness of the Network initiatives to position itself as a leading global player as regards Network (“the Network”) public health activities; by supporting the participation of its researchers in major global public health challenges. These programs will leverage brings together 32 training; international projects, encouraging openness across its institutes knowledge and scientific expertise in the fields of prevention and institutions united by the innovation and technology transfer. to pool resources (bioinformatics, biobanks, vectopole, treatment for the benefit of local populations. The Department of Pasteurian values and imaging) and emphasizing their attractiveness to international International Affairs will also continue its active policy of creating missions for the benefit of These activities are carried out with a view to promoting sustainable development, based researchers. I am confident in the Institut Pasteur International 4-year research groups (G4) to encourage talented young on developing local capabilities with respect for human rights and the environment. Network’s capabilities to draw inspiration from shared scientific scientists to return to the countries in which the institutes local populations. A unique ambitions, taking into account the diversity of scientific and are located. Active in 25 countries across 5 continents, model of cooperation in the The 32 member institutes of the Institut Pasteur International Network, partners and political environments, to increase the visibility and impact the Network acts to combat emerging diseases. This represents field of health, the Network associates in scientific research, public health services and education alliances, have of its research in global health. an outstanding base from which to develop international brings together men and signed the Institut Pasteur International Network Cooperation Agreement, which scientific cooperation. women who contribute on includes a Charter of Pasteurian Values adopted by all members of the network. These values include
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