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EQUIPMENT SHARING BROCHURE

Version May 21 CONTENTS:

INTRODUCTION 06 BIOINFORMATICS RESEARCH TECHNOLOGY PLATFORM 17 Bioinformatics Computational Biology Data Analysis Nucleotide Sequencing Big Data High Capacity Computing Programming genomics, WISB FLOW CYTOMETRY AND CELL SORTING FACILITY 08 metagenomics, transcriptomics, proteomics, single cell sequencing technologies, sequence assembly, regulatory sequence analysis Flow cytometry, FACS, cell sorting, BD, Fortessa, Fusion BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 FLOW CYTOMETRY FACILITY 08 bioinformatics, sequencing, data analysis, omic analysis, RNA-seq, DNA-seq, single cell genomics, bioinformatics training Flow, Cytometry, Flow Cytometry, FACS, Cell Sorting, Imaging Flow Cytometry, IFC, CFC, Single Cell Cloning, Single Cell, Training LEICESTER INSTITUTE OF STRUCTURAL AND CHEMICAL BIOLOGY 18 FLOW CYTOMETRY PLATFORM 09 Biological NMR spectroscopy, Protein-protein interactions, Protein-ligand interactions, Protein dynamics Flow Cytometry, FACS, Sorting, GCP, Training PROTEIN EXPRESSION FACILITY (PEF) 19 UNIVERSITY OF BIRMINGHAM CYTOF SERVICE 09 Recombinant protein production in Bacterial, S2 and Mammalian cells, University of Birmingham CyTOF, Helios, Mass Cytometry, metal isotope, University of Birmingham PROTEOMICS RESEARCH TECHNOLOGY PLATFORM 19 CONTAINMENT LEVEL 3 (C3) FACILITY 10 Proteomics, mass spectrometry, identification, quantification, post-translational modification, LC-MS, LC-MS/MS, peptide, protein, Hazard Group 3 organisms, Models of infection, Small rodent, Specialist training, Risk assessment for C3 organisms phosphorylation, validation

WARWICK ANTIMICROBIAL SCREENING FACILITY 10 ADVANCED MASS SPECTROMETRY FACILITY AT THE UNIVERSITY OF BIRMINGHAM 20 Drug discovery, Antimicrobial screening, Surface testing, Medical microbiology, Antimicrobial resistance, Medicine, Proteomics, mass spectrometry, identification, post-translational modification, peptide, protein Natural products, Microbiology, Robotic screening ADVANCED IMAGING TECHNOLOGIES 20 AUTOMATED HIGH-THROUGHPUT LIQUID HANDLING ANDMICROBIOREACTOR PLATFORMS 11 Fluorescence, Spinning Disk, Confocal, microscopes, WISB, Time-lapse, Nikon, Andor, Imaging Automation, liquid handling, high throughput, Tecan, screening, Antimicrobial, WISB, robotics, RoboLector, BioLector, microbioreactor, fermentations BIRMINGHAM ADVANCED LIGHT MICROSCOPY (BALM) 21 DEEP SEQ: NEXT GENERATION SEQUENCING FACILITY 11 Life and environmental sciences, Medical and Dental sciences, Fluorescent Light microscopy, Confocal (LCS) microscopy, TIRF, Structure Illumination, Next generation sequencing, Illumina, Oxford Nanopore Technologies, sequencing, single cell, optical mapping, bioinformatics, genomics, High throughput imaging, imaging analysis, trainings transcriptomics, DNA, RNA, 10X Genomics, Bionano ADVANCED IMAGING FACILITY 21 LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 Fluorescence microscopy, whole slide scanning, label free imaging, confocal laser microscopy, live cell imaging, image analysis, training Next Generation Sequencing, microarray, Illumina, 10X Genomics, single cell genomics transcriptomics, microRNA, RNA, DNA, RNA extraction, DNA extraction, digital droplet PCR, qPCR LATTICE LIGHT SHEET 22 CAMDU, Warwick, LLSM, Lattice, LightSheet, Microscopy, Light, Sheet, Live Cell, Dynamics NEUROELECTROPHYSIOLOGY AND ORGAN BATH PHARMACOLOGY LABORATORY 12 Neuroelectrophysiology, Organ Bath Pharmacology, Long-Term Potentiation (LTP), Microelectrodes, Neuronal Signalling, Epilepsy SLIM / SCHOOL OF LIFE SCIENCE IMAGING 22 Microscopy, Imaging, analysis, confocal, electron microscopy, histology CENTRE FOR HUMAN BRAIN HEALTH 13 COMPARE 23 Brain, MRI, MEG, EEG, OPM, Fnirs, sleep lab, Non-invasive brain stimulation Fluorescence, Microscopy, Super-Resolution, SIM, SMLM, STED, Light-Sheet, Lattice, SPIM, FRET, Photometry, TIRFM, image analysis ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 TECHNOLOGY HUB IMAGING FACILITY, COLLEGE OF MEDICAL AND DENTAL SCIENCES 23 Brain, MRI, MEG, EEG, neuropsychology lab, neurosensory lab, sleep lab, TMS, Non-invasive brain stimulation Imaging Suite Laser scanning Wide field fluorescence microscopy Live cell imaging Slide scanning Lightsheet microscopy STEMLAB BIOSUITE 14 CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 Plate Readers, Bioscience, Microbiology, Tissue Culture, Spectrophotometry, Microscopy Transmission Electron Microscopy, TEM, Scanning Electron, Microscopy, SEM, Ultramicrotomy, Critical Point Drying, Negative, staining, Immunolabelling, CLEM, Biological sample preparation LABEL FREE BIOMOLECULAR INTERACTION ANALYSIS 14 SPR, Biacore, ITC, MicroCal, Microscale thermophoresis, Monolith, biomolecular, WISB, affinity, kinetics, thermodynamics, protein-protein, labe ADVANCED BIOIMAGING RTP 24 Cryo-TEM, transmission electron microscopy, biological samples, cellular ultrastructure, nanoparticles, size measurements, negative stain, HEALTH AND LIFE SCIENCES 15 ultrathin sectioning Tablet preparation, tablet testing, dissolution testing MIDLANDS REGIONAL CRYO-EM FACILITY 25 SCHOOL OF SPORT, EXERCISE AND HEALTH SCIENCES 15 Cryo-TEM, transmission electron microscopy, biological samples, structure, single particle analysis, tomography Blood Cell Counter , Dexa Scan, Mri, Ultrasound, Cortex And Carefusion Gas Analysis-Hokanson THIN SECTION LABORATORY 25 MITOCHONDRIAL PROFILING CENTRE 16 Thin sections, micromorphology, polished blocks Mitochondria, metabolism, oxygen consumption, oxidative phosphorylation, high resolution respirometry, Seahorse Extracellular Flux Analysis, cells, tissue ROCK PREPARATION AND THIN SECTIONING FACILITY 26 Thin sections, Polished blocks, Stubs, Core drilling PLANT GROWTH FACILITY 16 Plant growth, soil-crop systems, plant and root phenotyping, pre-harvest, post-harvest, crop monitoring, climate change studies, seed technology, THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 crop establishment, agrochemicals, biostimulants, biopesticides Nanomaterials, Surface Analysis, Imaging, Chemistry, Pharmacy, Engineering, TEM, SEM, XPS, Raman, CryoEM Lithography, OrbiSIMS

PHENOME CENTRE BIRMINGHAM 17 ELECTRON MICROSCOPY RESEARCH TECHNOLOGY PLATFORM 27 Metabolics, biomarkers Electron Microscopy, Transmission EM, Scanning Transmission EM, Scanning EM (FEG), Focused Ion Beam SEM

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ANALYTICAL SCANNING ELECTRON MICROSCOPY AND AUTOMATED MINERALOGY 27 AEROSPACE INTEGRATION RESEARCH CENTRE (AIRC) 37 Scanning Electron Microscopy, EDS, WDS, micro-XRF, Automated Mineralogy, Imaging, Materials Aerospace technologies and integration, aircraft, airspace, flight simulators, air traffic management, air transportation, unmanned aerial vehicles, engineering photonics, intelligent automation WMG ELECTRON MICROSCOPY SUITE 28 Scanning Electron Microscopy, Focused Ion Beam, (Scanning) / Transmission Electron Microscopy, Precession Electron Diffraction, CRANFIELD IMPACT CENTRE (CIC) 38 X-ray Fluorescence Spectroscopy, Nanoindentation Crash and impact testing, crashworthiness, vehicle safety, accident reconstruction, vehicle engineering, lightweight structures and materials, sled testing of structures and dummies CENTRAL ELECTRON MICROSCOPE UNIT 28 Electron Microscopy, Transmission Electron Microscopy, TEM, Scanning Electron Microscopy, SEM GEOGRAPHY AND ENVIRONMENT 38 Geography, Soils, Sediment, Water Analysis, Ion Chromatography, Total Organic Carbon (TOC), Laser Particle Sizer, Spectrophotometer X-RAY FLUORESCENCE SPECTROMETRY FACILITY (XRF) 29 X-Ray Fluorescence spectrometer, pXRF, powder pellets, fusion beads, analytical balances, furnaces, drying ovens ENVIRONMENTAL ANALYTICAL FACILITY (EAF) 39 Gas and liquid chromatography, metals analysis, wastewater analysis and water treatment technologies, soil analysis, microbiology and mycology, X-RAY DIFFRACTION RTP 29 plant molecular biology, post harvest analytical techniques, environmental chemistry, membrane sciences, volatilesevaluation, algae growth and X-ray Diffraction, XRD, SAXS, XRF, High-resolution, Scattering, powder XRD, Structural solution, nanomaterials, reflectivity, stress, texture, harvesting, small scale anaerobic digestion, complete gas handling system GISAXS, non-ambient SOIL MANAGEMENT FACILITY 39 CHEMISTRY X-RAY CRYSTALLOGRAPHY 30 Soil management and erosion, crops, water, agricultural machinery, off-road vehicles, agrochemicals, cultivation, sowing, rainfall, hydrological Crystallography, X-ray diffraction, single crystal, powder crystal processes, geotextiles, runoff, meteorological data, weeding, pesticides

WARWICK PHOTOEMISSION FACILITY 30 NATIONAL RESEARCH FACILITY FOR WATER AND WASTEWATER TREATMENT 40 X-Ray Photoelectron Spectroscopy, XPS, Ultraviolet Photoelectron Spectroscopy, UPS, Surface Analysis, Surface Science, Surface Chemistry, Sewage treatment, drinking water treatment, wastewater, water science, pilot facility, water monitoring and testing Composition Analysis, Materials, Angle-Resolved Photoemission, ARPES, Low Energy Electron Diffraction, LEED WARWICK THERMAL ENERGY FACILITY 40 (LA)-ICP-MS 31 Thermal Analysis, Materials Testing, Thermal Conductivity, Calorimetry, Dilatometry, Sorption, Solar Simulator, Humidity, Heating and Cooling LA-ICP-MS, ICP-MS, laser, Inductively coupled plasma mass spectrometry, trace elemental analysis WOLFSON SCHOOL ELECTRONICS WORKSHOP AT 41 SCHOOL OF CHEMISTRY MASS SPECTROMETRY AND CHROMATOGRAPHY 31 Printed Circuit Board (PCB), Arduino, Micro-Controllers, Electrical Cabinets, CAD, Ultimaker Mass spectrometry, LC-MS, accurate mass, GC-MS, HPLC, MALDI, electron ionisation CRANFIELD ORDNANCE TEST AND EVALUATION CENTRE (COTEC) 41 VOC AND GAS ANALYSIS FACILITY 32 Defence and security, firing range, munitions testing, ammunition proofing, ordnance proofing, explosive trials, bullet and fragment attack, Electronic nose, Machine olfaction, gas analysis, VOC analysis, GC-MS, headspace analysis, Portable VOC measurements fragmentation trials, testing and evaluation, flare test track, high altitude test facility, pyrotechnics

SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 SCIENTIFIC COMPUTING RESEARCH TECHNOLOGY PLATFORM (SC RTP) 42 Flavour, Aroma, Taste, Volatile Aroma Compounds, GC-MS, gas phase analysis, MS-NOSE, Real time release Scientific Computing, Research Computing, Research Software Engineering, High Performance Computing, Linux

UK HIGH-FIELD SOLID-STATE NMR FACILITY 33 CENTRE FOR MATHEMATICAL COGNITION 42 Solid-state NMR, Magic Angle Spinning (MAS), battery technology, pharmaceuticals, plant cell wall physiology, protein structural biology Eye-tracking (VR, remote and mobile); Psychophysiology (fixed and mobile GSR, ECG, EMG), Observation (fixed and mobile)

NOTTINGHAM DNP MAS NMR FACILITY 33 KEELE UNIVERSITY SMART ENERGY NETWORK DEMONSTRATOR 43 Nuclear Magnetic Resonance, Dynamic Nuclear Polarization, Spectroscopy, Analytical Chemistry, Structural Studies, Catalysts, Smart Energy Network Demonstrator, Intelligent Energy Generation, Living Laboratory Energy materials, Biomolecules GLOSSARY 44 POLYMER CHARACTERISATION RESEARCH TECHNOLOGY PLATFORM 34 GPC, SEC, Gel Permeation Chromatography, Size Exclusion Chromatography, Polymer Analysis, Polymer Characterisation, TGA, DSC, DMA, Thermal Analysis, Materials Testing

MICRO-FOCUS X-RAY COMPUTED TOMOGRAPHY AT WMG 34 X-ray Computed Tomography, NDT, Micro-focus XCT, High-power XCT, In-situ scanning, Material characterisation, Digital imaging

CRANFIELD FORENSIC INSTITUTE (CFI) 35 forensic science, archaeology, anthropology, entomology, autopsy, crime scene investigation, digital forensics, materials science, heritage crime

WARWICK CENTRE FOR ULTRAFAST SPECTROSCOPY 35 Ultrafast spectroscopy, terahertz spectroscopy, semiconductors, quantum materials, photostability, prodrugs and nanomedicine, infrared spectrsocopy, ultraviolet spectroscopy, transient absorption spectroscopy, fluorescence spectroscopy

SPECTROSCOPY RTP 36 Optical Spectroscopy, Raman, FT-IR, UV-Vis, Electron Paramagnetic resonance EPR, Photoluminescence, Materials, Imaging

WARWICK LASER MICROMACHINING 36 Laser Micromachining, Drilling, Milling, Cutting, Composites, Polymers, Metal, Diamond, Mask Fabrication, Complex Geometries, Surface Roughening

MULTI-USER ENVIRONMENT FOR AUTONOMOUS VEHICLE INNOVATION (MUEAVI) 37 Intelligent and autonomous vehicles, mechatronics, simulation, intelligent mobility, urban and off-road environment, test track, infrastructure sensor development, traffic, instrumented vehicles, advanced vehicle engineering, emerging technologies

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TECHNICIAN LED ‘’THE FOUNDATIONS OF THE MIDLANDS EQUIPMENT SHARING INNOVATION (MI) PARTNERSHIP WAS BUILT ON ESTABLISHING HOW TO MORE EFFECTIVELY SHARE OUR RESEARCH EQUIPMENT. IT IS A Midlands Universities have delivered many world class I am encouraged by the fantastic engagement we have had research impacts. Often these have required equipment, from our technical community in delivering this brochure. NATURAL EVOLUTION THAT OUR TECHNICAL facilities and research infrastructure and frequently they have The range of submissions are diverse, from high-throughput STAFF BECOME THE DRIVING FORCE OF been enabled only through the work of highly skilled technical sequencing, to world leading solid state NMR and even testing specialists. The Technician Led Equipment Sharing project is for munitions! We very much envisage this brochure as a living THIS DUE TO THE VITAL KNOWLEDGE AND a fantastic opportunity to demonstrate what can be achieved document with regular updates, both to allow the addition by our technical specialists driving the equipment sharing of new facilities and also to keep the information current. EXPERIENCE WHICH THEY BRING. THIS WORK agenda across (MI). We are proud to host Lastly, I really encourage all colleagues across MI to take a TO EMPOWER TECHNICIAN-LED EQUIPMENT significant and sometimes unique facilities across MI. We are closer look at what is available and make contact to see how also cognisant that our expert technical teams are essential your research can make use of the knowledge and facilities SHARING WILL FURTHER STRENGTHEN to maximising the potential of this resource, and by providing available. By sharing these resources, ultimately, we will access to both facilities and knowledge, they will greatly accelerate and add-value to the world-class research COLLABORATIONS ACROSS MI.’’ advance both basic research and realisation of impact. portfolio across MI which in turn will deliver impact that will benefit us all. We will build on the best practice already demonstrated DR HELEN TURNER, by our technical community over the next four years. The TALENT CO-LEAD AND Technician Led Equipment Sharing component of TALENT MIDLANDS INNOVATION DIRECTOR will have equipment showcases both virtually and at each institution, an equipment sharing fund to stimulate sharing by overcoming financial constraints, and this brochure to highlight the facilities and expertise researchers can access. We know this will be the catalyst for fostering new collaborations s across the whole of MI with colleagues from all partners being involved. Our work will increase the visibility of the expertise our technical specialists have, lead to greater recognition of the services provided and increase the sustainability of facilities at a time when finances are going to be under more pressure than ever before.

PROFESSOR SAM KINGMAN Chair of the Midlands Research Infrastructure Committee & Pro-Vice-, University of Nottingham

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WISB FLOW CYTOMETRY AND UNIVERSITY OF BIRMINGHAM CELL SORTING FACILITY FLOW CYTOMETRY PLATFORM

Two cytometry instruments (one analyser and one sorter) with The Flow Cytometry platform at the University of Birmingham complementary laser (355, 405, 488, 561 and 640 nm) and filter supports flow cytometry and cell sorting across the University arrangements form part of the Warwick Integrative Synthetic of Birmingham. We provide a range of services from user Biology Research Technology Facility (WISB RTF). The suite training on standard self-service instruments, through to a includes a BD Fortessa Flow Cytometer with the potential for bespoke service of cell sorting. The platform has recently high-throughput analysis and a BD FACSAria Fusion Cell Sorter. expanded into the delivery of GCP level flow cytometry, in our dedicated GCP level laboratories within the ITM. The Flow The sorter is enclosed in a Class 2 biosafety cabinet providing Cytometry Unit is accessible to all current students and staff, operator and sample protection. It is possible to sort into tubes all UK academics and commercial organisations. or 96 well plates, including single cell sorting. A temperature control system can be used to optimise conditions for cell survival. The WISB RTF manager is happy to discuss the potential of using this equipment for your experiments.

UNIVERSITY OF WARWICK UNIVERSITY OF BIRMINGHAM Key Contact: Sarah Bennett Key Contact: Andrea Mitchell Email: [email protected] Email: [email protected] KEYWORDS: Telephone: 02476523927 KEYWORDS: Telephone: 0121 415 8013 Website: https://www.wisb-uow. Website: https://www.birmingham.ac.uk/university/ Flow cytometry, FACS, cell sorting, BD, Fortessa, Fusion co.uk/technology-facilities/ Flow Cytometry, FACS, Sorting, GCP, Training colleges/mds/facilities/flow-cytometry.aspx Twitter: @WISB_SynBioCtre Facebook: Flowcytometry Bham

UNIVERSITY OF NOTTINGHAM CYTOF AND BIRMINGHAM FLOW CYTOMETRY FACILITY FLOW CYTOMETRY

The University of Nottingham Flow Cytometry Facility provides Mass Cytometry (CyTOF) service is a part of the Flow Cytometry a fully comprehensive Flow Cytometry and Cell Sorting Service platform at the University of Birmingham. Our available open to all research groups across the University, Midlands equipment is Helios™, a CyTOF® system which comprises the Innovation and, by agreement, to external parties. most recent advances in mass cytometry and is designed to provide a new and improved tool for bioanalytical single-cell We provide access to high end imaging and conventional flow detection and analysis through 135 channels. We provide cytometers as well as a full range of training and support support and a bespoke service to researchers at the University designed to make your flow cytometry experiments a success. of Birmingham and across the country to a GCP standard.

UNIVERSITY OF NOTTINGHAM UNIVERSITY OF BIRMINGHAM Key Contact: David Onion Email: [email protected] Key Contact: Adriana Flores-Langaric KEYWORDS: Telephone: 0115 82 30740 KEYWORDS: Email: [email protected] Website: https://www.nottingham.ac.uk/life-sciences/ Telephone: 1214158013 Flow, Cytometry, Flow Cytometry, FACS, Cell Sorting, Imaging Flow facilities/flow-cytometry-facility/index.aspx CyTOF, Helios, Mass Cytometry, metal isotope, Website: https://www.birmingham.ac.uk/university/ Cytometry, IFC, CFC, Single Cell Cloning, Single Cell, Training Twitter: @UoNFCF University of Birmingham colleges/mds/facilities/flow-cytometry.aspx

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CONTAINMENT LEVEL 3 AUTOMATED HIGH-THROUGHPUT (C3) FACILITY LIQUID HANDLING AND MICROBIOREACTOR PLATFORMS

This facility provides a laboratory suite to work safely with Two robotic liquid handling platforms with integral devices ACDP Hazard Group 3 microorganisms. One facility contains (colony picker, plate reader, incubators, thermocycler, vacuum four individual laboratories with microbiological safety cabinets filtration system and heating/cooling/shaking plate holders) (MSC) in each where all bacterial or viral manipulation occurs and a high-throughput Microbioreactor are available for the and other equipment essential for working with microorganisms automation of high-throughput protocols; such as screening, and their safe storage. A second C3 Facility (located in the plate replication, DNA extractions, transformations and Pre-Clinical Research Facility) is fitted with bespoke MSCs and bioprocess optimisation. other specialized equipment to carry out work with murine of infection including aerosol. The equipment is part of the Warwick Integrative Synthetic Biology Research Technology Facility (WISB RTF) and in We provide training to staff and students to meet compliance addition, provides services as part of the Warwick Antimicrobial required to access this type of facility and assistance for Screening Facility. The WISB RTF manager is happy to discuss documentation, experimental procedure design and risk the potential of automating your applications. assessment. If you would like to know more about the facility, contact us at [email protected] UNIVERSITY OF WARWICK Key Contact: Sarah Bennett Key Contact: Marialuisa Crosatti KEYWORDS: Email: [email protected] KEYWORDS: Email: [email protected] Telephone: 02476523927 Telephone: 0116 373 6456 Automation, liquid handling, high throughput, Tecan, screening, Website: https://www.wisb-uow. Hazard Group 3 organisms, Models of infection, Small rodent, Website: https://www2.le.ac.uk/colleges/ Antimicrobial Screening, WISB, robotics, RoboLector, BioLector, co.uk/technology-facilities/ Specialist training, Risk assessment for C3 organisms medbiopsych/facilities-and-services/cbs/c3 microbioreactor, fermentations Twitter: @WISB_SynBioCtre

WARWICK ANTIMICROBIAL DEEP SEQ: NEXT GENERATION SCREENING FACILITY SEQUENCING FACILITY

Antimicrobial screening is the first step of antimicrobial drug The sequencing facility offers research scientists access to discovery to identify suitable candidates against bacterial state of the art high-throughput sequencing technology. Our and fungal infections. Antimicrobial susceptibility testing experienced team of dedicated experimental scientists and ascertains the effectiveness of candidates against a panel of bioinformaticians offer support with experimental design, target organisms, such as the ESKAPE pathogens (Enterococcus library prep, sequencing and bioinformatics as required. Deep faecium, Staphylococcus aureus, Klebsiella pneumoniae, Seq houses the Illumina MiSeq and NextSeq500, which can Acinetobacter baumannii, Pseudomonas aeruginosa, and supply single or paired reads from 75 to 600 cycles. Enterobacter species), or custom selections of clinically or industrially relevant microorganisms. DeepSeq are experts in the long read Oxford NanoPore Technologies platforms, we house the MinION, GridION and Toxicity studies towards representative mammalian cell lines PromethION platforms. DeepSeq also runs the Bionano SaphyrII provide an initial assessment of suitability for clinical use and for optical mapping as well as the 10X Genomics Chromium can be used to narrow the pool of candidates to those that platform for single cell applications and work with groups on are selectively active against microbes.Risk assessment of 10X Genomics spatial transcriptomics projects. antimicrobial resistance generation evaluates the effective lifespan of a candidate drug. UNIVERSITY OF WARWICK UNIVERSITY OF NOTTINGHAM KEYWORDS: Key Contact: John Moat KEYWORDS: Key Contact: Victoria Wright Email: [email protected] Email: [email protected] Drug discovery, Antimicrobial screening, Surface testing, Medical Telephone: 07795232881 Next generation sequencing, Illumina, Oxford Nanopore Technologies, Telephone: 0115 82 30665 microbiology, Antimicrobial resistance, Medicine, Natural products, Website: https://warwick.ac.uk/fac/cross_fac/amrscreening sequencing, single cell, optical mapping, bioinformatics, genomics, Website: https://www.nottingham.ac.uk/deepseq/ Microbiology, Robotic screening LinkedIn: www.linkedin.com/in/john-moat-23b6b979 transcriptomics, DNA, RNA, 10X Genomics, Bionano Twitter: @DeepSeqNotts

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LEICESTER GENOMICS CORE CENTRE FOR HUMAN FACILITY (NUCLEUS) BRAIN HEALTH

The Leicester Genomics Facility offers solutions for researchers It is an interdisciplinary brain research facility established with the to conduct research in genomics. Researchers are assisted from mission of understanding what makes a brain healthy, how to maintain the experimental design through to the publication of their it, and how to prevent and reverse damage. The CHBH is at the forefront work. They can access Illumina next generation sequencing with of understanding how the brain binds together separate processes and forensic capability, sequencing library preparation, microarray, allocates resources through the coordination of large-scale oscillatory qPCR, digital droplet PCR, 10x Genomics single cell genomics, activity, and in using these mechanisms to understand cognitive function. Oxford Nanopore MinION, and automated DNA/RNA isolation. The facility has contributed to the publication of multiple Our research facilities include the following: articles. It is part of the Leicester Core Biotechnology Services, - Magnetic resonance imaging (MRI) which includes expertise beyond genetics. This structure facilitates the development of multi-disciplinary projects, such - Magnetoencephalography (MEG) as spatial transcriptomics and custom bio-analysis pipelines. - Electroencephalography (EEG) - Optically Pumped Magnetometers (OPM) - Functional near infrared (fNIRS) - Sleep labs - Non-Invasive Brain Stimulation UNIVERSITY OF BIRMINGHAM UNIVERSITY OF LEICESTER KEYWORDS: Key Contact: Emily Loftus Key Contact: Dr Nicolas Sylvius Next Generation Sequencing, microarray, Illumina, 10X Genomics, KEYWORDS: Email: [email protected] Email: [email protected] single cell genomics transcriptomics, microRNA, RNA, DNA, RNA Telephone: 0121 414 6261 Telephone: 01162523365 Brain, MRI, MEG, EEG, OPM, Fnirs, sleep lab, Non-invasive extraction, DNA extraction, digital droplet PCR, qPCR Website: www.birmingham.ac.uk/research/ Website: https://le.ac.uk/cbs/facilities/nucleus brain stimulation centre-for-human-brain-health

NEUROELECTROPHYSIOLOGY ASTON INSTITUTE OF HEALTH AND ORGAN BATH & NEURODEVELOPMENT PHARMACOLOGY LABORATORY

The combined neuroelectrophysiology and organ bath The Aston Neuroimaging Facility is a key research facility pharmacology laboratory at provides staff within the Aston Institute of Health & Neurodevelopment (IHN), and students with the ability to examine first-hand the effects exploiting advanced technology to explore brains, development of drugs on living brain slices (equipment pictured) or on a and healthy behaviours. Our research in children spans four variety of other organs, such as hearts, intestines, lungs, etc. crosscutting areas of research strength (Social Cognition/ The main purpose of the lab is to study the processes behind Autism, Reading/Dyslexia, Epilepsy, Eating/Nutrition, and long-term potentiation (LTP) using hippocampal brain slices extends from ‘bench to bedside’; our discoveries become the and probing the desired areas with microelectrodes. next advances in healthcare and educational policy for literacy, eating and neurodevelopmental disorders. IHN's capabilities Drugs can be administered in a controlled fashion to enhance, in advanced technologies, child-centred assessments/ reduced, or completely block neuronal signalling. Neurological technologies and Care Quality Commission registered clinical conditions, such as epilepsy, can also be induced and examined. service create a rich hub of opportunity for research. Further information, interest in the laboratory or to discuss training/advice can be discussed via the contact information.

UNIVERSITY OF ASTON ASTON UNIVERSITY Key Contact: Dr Karen Woodhall KEYWORDS: KEYWORDS: Email: [email protected] Key Contact: Dani Burrell (Neuroscience Technician) Website: www.aston.ac.uk/lhs/research/groups/ Neuroelectrophysiology, Organ Bath Pharmacology, Long-Term Email: [email protected] Brain, MRI, MEG, EEG, neuropsychology lab, neurosensory lab, aston-institute-of-health-and-neurodevelopment Potentiation (LTP), Microelectrodes, Neuronal Signalling, Epilepsy Telephone: 0121 204 3156 sleep lab, TMS, Non-invasive brain stimulation Twitter: @Aston_IHN

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STEMLAB HEALTH AND LIFE SCIENCES BIOSUITE

The STEMLab BioSuite is a fully operational facility equipped Pharmaceutical equipment for the preparation and testing of for Biochemistry, molecular biology, and microbiology. tablet formulations; Riva mini press (13mm flat faced punch), Equipment includes FluoStar Omega plate readers, Flow dissolution baths, disintergration baths, tablet hardness testers. Cytometer, GelDoc and ChemiDoc Biorad imagers, optical microscopes, GeneSys spectro-photometers, bioreactors, Biological Safety Cabinets in a purpose build cell culture lab. This facility is predominantly a teaching facility shared across Schools and their respective disciplines, such as Biology, Biochemistry, Medicinal Chemistry, and Chemical Engineering. With a vast array of technical support, we are happy to share our expertise and knowledge.

LOUGHBOROUGH UNIVERSITY ASTON UNIVERSITY Key Contact: Eleanor Braithwaite KEYWORDS: Email: [email protected] KEYWORDS: Key Contact: Christine Jakeman Telephone: 01509 228 461 Email: [email protected] Plate Readers; Bioscience; Microbiology; Tissue Culture; Website: https://www.lboro.ac.uk/ Tablet preparation, tablet testing, dissolution testing Telephone: 01212043969 Spectrophotometry; Microscopy, flow cytometry study/stemlab/insidestemlab/ Website: https://www.aston.ac.uk/

LABEL FREE BIOMOLECULAR SCHOOL OF SPORT, INTERACTION ANALYSIS EXERCISE AND HEALTH SCIENCES

Three individual instruments for the analysis of biomolecular Ranked number 1 in the world QS world university rankings, interactions form part of the Warwick Integrative Synthetic SSEHS has a worldwide reputation for advancing research Biology Research Technology Facility (WISB RTF). The suite and knowledge in medicine, cellular and molecular biology, includes a Biacore T200 for Surface Plasmon Resonance (SPR), a nutrition, biomechanics, physiology, sport psychology and Monolith NT.115 for Microscale Thermophoresis and a MicroCal sport management. Here at Loughborough we have outstanding VP-ITC for Isothermal Titration Calorimetry. facilities and world class equipment, such as sports equipment, cortex and CareFusion online gas analysis, ECG, Hokanson and These instruments can be used to determine the affinity and Horiba blood cell counter. We are also home to the National binding kinetics of a ligand to its receptor. Examples of the Centre for Sport Exercise and Medicine East Midlands. various bond types include protein-protein, protein-DNA, receptor-drug, enzyme-substrate. The WISB RTF manager is Our researchers are also able to access diagnostic imagery happy to discuss the potential of using this equipment for your such as, ultrasound, x-ray, dexa scan and MRI. Technical staff biomolecular interaction analyses. support teaching and research across different sectors, almost all technical staff are trained in phlebotomy. We are happy to discuss any support and / or equipment queries. UNIVERSITY OF WARWICK Key Contact: Sarah Bennett LOUGHBOROUGH UNIVERSITY KEYWORDS: Email: [email protected] Telephone: 02476523927 KEYWORDS: Key Contact: Clare Smith (Laboratory assistant (NCSEM)) SPR, Biacore, ITC, MicroCal, Microscale thermophoresis, Website: https://www.wisb-uow. Email: [email protected] Monolith, biomolecular, WISB, affinity, kinetics, thermodynamics, co.uk/technology-facilities/ Blood Cell Counter, Dexa Scan, Mri, Ultrasound, Cortex And Telephone: 01509 228225 protein-protein, label free Twitter: @WISB_SynBioCtre Carefusion Gas Analysis-Hokanson Website: https://www.lboro.ac.uk/departments/ssehs/

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MITOCHONDRIAL PROFILING PHENOME CENTRE CENTRE BIRMINGHAM

Over the last two decades it has become increasingly important Phenome Centre Birmingham offers a complete collaborative service to to identify and quantify changes in specific components that academic, industry, and government partners, providing expertise and advice constitute mitochondrial function for understanding relationships in metabolic phenotyping studies from conception and experimental design between bioenergetics and changes in a cells phenotype. At through data acquisition to data analysis and biological interpretation. the Mitochondrial Profiling Centre, we provide a number of services to support state-of-the art high resolution respirometry Phenome Centre Birmingham conducts metabolic phenotyping studies with and extracellular flux analysis to probe real-time functional the following objectives: measurements of mitochondrial and cellular bioenergetics in - To understand molecular mechanisms associated with human ageing, different biological samples including, isolated mitochondria, disease onset and progression. intact cells, permeabilized tissue and tissue homogenates. - To identify metabolic biomarkers for stratification of the human population to be applied in risk stratification of developing a specific disease, in diagnosis of a disease, in defining progression or remission from a disease, and in the identification of responders and non-responders to nutritional, exercise or drug interventions. - To understand molecular mechanisms and identify metabolic markers associated with human toxicology. UNIVERSITY OF BIRMINGHAM UNIVERSITY OF BIRMINGHAM KEYWORDS: Key Contact: Warwick Dunn Key Contact: Jonathan Barlow KEYWORDS: Email: [email protected] Mitochondria, metabolism, oxygen consumption, oxidative Email: [email protected] Telephone: 0121 414 5458 phosphorylation, high resolution respirometry, Seahorse Telephone: 7970411964 Metabolics, biomarkers Website: https://www.birmingham.ac.uk/ Extracellular Flux Analysis, cells, tissue Website: https://www.birmingham.ac.uk/facilities/mpc research/activity/phenome-centre

PLANT GROWTH FACILITY BIOINFORMATICS RESEARCH TECHNOLOGY PLATFORM

Cranfield is home to a range of plant growth facilities for The Warwick Bioinformatics RTP provides access to the experimental work involving plant physiology, plant phenotyping, computational skills and expertise required for accurate plant-microbe interactions, and plant-soil interactions. interpretation of data from high-throughput biomedical experiments. The facilities are home to a unique platform for assessing pilot Our team provides assistance across a broad range of data types scale crop-soil systems and sensor development, and include and platforms and at all stages of the experimental procedure; from a 9m high, 300m2 Venlo glasshouse housing an overhead consultation on experimental design, through the implementation of LemnaTec sensor gantry; a 4m high, 230m2 Venlo glasshouse cutting edge data analysis pipelines and interpretation, to delivering with three compartments, including thermal screens, roof results as figures and as interactive web tools. Please contact us to vents, supplementary lighting, electric heating and automatic discuss how we can help with your research. irrigation; and four 10.5m2 walk-in Weiss plant growth rooms with temperature (15-35°C), relative humidity (60-95%) and supplementary CO2 and LED lighting. Key Contact: Ceri Dawson Email: [email protected] UNIVERSITY OF WARWICK KEYWORDS: Telephone: 01234 750111 ext. 5666 KEYWORDS: Website: https://www.cranfield.ac.uk/ Key Contact: Sascha Ott, Richard Stark Plant growth, soil-crop systems, plant and root phenotyping, facilities/plant-growth-facility Bioinformatics Computational Biology Data Analysis Nucleotide Email: [email protected] pre-harvest, post-harvest, crop monitoring, climate change studies, Linkedin: https://www.linkedin.com/ Sequencing Big Data High Capacity Computing Programming genomics, Telephone: 024 761 50258 / 024 765 74266 seed technology, crop establishment, agrochemicals, biostimulants, school/cranfield-university/ metagenomics, transcriptomics, proteomics, single cell sequencing Website: https://warwick.ac.uk/ biopesticides Twitter: @CranfieldUni technologies, sequence assembly, regulatory sequence analysis research/rtp/bioinformatics/

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BIOINFORMATICS ANALYSIS PROTEIN EXPRESSION SUPPORT HUB (BASH) FACILITY (PEF)

The Leicester Bioinformatics Analysis Support Hub (BASH) provides The PEF acts as a focal point for advice about all aspects of bioinformatic and clinical informatic support to researchers in the recombinant protein production in Bacterial, S2 and Mammalian design, planning, analysis and reporting of their research studies. cells. The variety of proteins currently produced are used in a wide Services include experimental design of projects, bioinformatic analysis range of downstream applications and the PEF aims to be responsive and reporting of high throughout sequencing and microarray data, to customer needs where possible. The PEF resides within a database development and management, and regular training through designated, fully-equipped laboratory suite and provides a central workshops and courses on bioinformatics. The facility works in close location to undertake recombinant protein expression within a collaboration with other facilities of the Leicester Core Biotechnology dedicated space. We provide a range of expression and purification Services, including the Genomics Core Facility, to prepare grant services or training which can be commissioned at any time. Current proposals and experimental design. activities are distributed across the Birmingham campus research community, but the PEF welcomes collaboration with Midlands Innovation and external companies.

UNIVERSITY OF BIRMINGHAM UNIVERSITY OF LEICESTER Key Contact: Jamie Webster KEYWORDS: Key Contact: Dr Jin-li Luo KEYWORDS: Email: [email protected] Email: [email protected] Telephone: +44 (0)121 414 9266 Bioinformatics, sequencing, data analysis, omic analysis, RNA-seq, Telephone: 0116 252 5822 Recombinant protein production in Bacterial, S2 and Mammalian Website: https://www.birmingham.ac.uk/university/ DNA-seq, single cell genomics, bioinformatics training Website: https://le.ac.uk/cbs/facilities/bbash cells, University of Birmingham colleges/mds/facilities/protein-expression-facility.aspx

LEICESTER INSTITUTE PROTEOMICS RESEARCH OF STRUCTURAL AND TECHNOLOGY PLATFORM CHEMICAL BIOLOGY

The Leicester Institute of Structural and Chemical Biology was created The Proteomics RTP provides service to researchers seeking to in 2016 to bring together established strengths in structural biology, identify and quantify proteins and their modifications. The analysis chemical biology and single-molecule research from across the Colleges. of protein mixtures from gel slices, co-immunoprecipitations The high field NMR spectrometers in the institute enable superior levels or enrichments is routine and we can identify several thousand of sensitivity and resolution. We are one of the few centres to combine proteins in complex samples such as, cell lysates and tissue extracts. both solution and solid state NMR to answer biological questions. You will find support from an enthusiastic team to help with Solution–state NMR allows the study of protein structure and dynamics scientific discussion, experimental design, sample preparation, under physiological conditions, whereas solid-state NMR alleviates analysis of data and provision of training. Orbitrap Fusion with molecular weight limitations allowing the study of high molecular UltiMate 3000 RSLCnano System weight complexes or of proteins embedded in lipid bilayers. • Identify and Quantify unknowns from complex mixtures For further information about the facility please contact us. using LC-MS Quantiva triple quadrupole with UltiMate 3000 RSLCnano System • Validate targets generated from analysis of complex mixtures using LC-MS. UNIVERSITY OF WARWICK UNIVERSITY OF LEICESTER Key Contact: Dr Andrew Bottrill Key Contact: Fred Muskett KEYWORDS: Email: [email protected] KEYWORDS: Email: [email protected] Telephone: 02476 574182 Telephone: 0116 2297096 Proteomics, mass spectrometry, identification, quantification, Website: https://warwick.ac.uk/fac/sci/ Biological NMR spectroscopy, Protein-protein interactions, Website: https://le.ac.uk/liscb post-translational modification, LC-MS, LC-MS/MS, peptide, protein, lifesci/research/facilities/proteomics/ Protein-ligand interactions, Protein dynamics Facebook: @UniofLeicester phosphorylation, validation Twitter: @RTP_Warwick

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ADVANCED MASS BIRMINGHAM ADVANCED SPECTROMETRY FACILITY AT THE LIGHT MICROSCOPY (BALM) UNIVERSITY OF BIRMINGHAM

The Advanced Mass Spectrometry Facility (AMSF) supports Located in the School of Biosciences at the University of Birmingham, the medical and biological research with cutting edge proteomics, Birmingham Advanced Light Microscopy (BALM) facility provides state native mass spectrometry, and imaging mass spec. of the art imaging equipment and techniques for the medical, life and environmental sciences. BALM offers a range of services from user training Using state-of-the-art high resolution mass spectrometry on standard equipment through collaborative microscopy experiments, (including the first Thermo Lumos-Eclipse in a UK research assisted sessions and imaging analysis. Advanced fluorescence imaging facility), we provide cutting edge top-down and bottom- systems (including Confocal, TIRF, SIM and widefield), are routinely used for up proteomics, identification of protein-protein and high resolution imaging of samples ranging between microbacteria, biofilms, protein-ligand interactions, PTM analysis, and native mass cancer cells, drosophila, zebrafish, Arabidopsis and more. spectrometry services. Together with other two sisters facilities (Technology Hub and COMPARE), Additionally, we are involved with the development of high BALM is part of the Imaging Suite, a cross college group of imaging facilities sensitivity mass spectral imaging techniques and continue accessible to all internal and external (commercial and academic). All the to apply our expertise in instrument development to imaging specialists are available to discuss microscopy experiments at all expanding the range of capabilities for both our collaborating levels, preliminary data acquisition, grant submissions advices, costing and UNIVERSITY OF BIRMINGHAM researchers and clients. any other questions on equipment and techniques. Key Contact: Dr. Alessandro Di Maio (BALM imaging specialist) UNIVERSITY OF BIRMINGHAM Other Contact: Dr. Andrea Mitchell (Technical KEYWORDS: Lead for Imaging and Flow Cytometry) Key Contact: Todd Mize Email: [email protected] KEYWORDS: Life and environmental sciences, Medical and Dental sciences, Fluorescent Email: [email protected] Telephone: 0121 414 5398 Light microscopy, Confocal (LCS) microscopy, TIRF, Structure Illumination, Proteomics, mass spectrometry, identification, post-translational Website: www.birmingham.ac.uk/facilities/ Website: https://www.birmingham.ac.uk/ High throughput imaging, imaging analysis, trainings, microscopy modification, peptide, protein advanced-mass-spectrometry facilities/balm/index.aspxhs/

ADVANCED IMAGING ADVANCED IMAGING TECHNOLOGIES FACILITY

A Spinning Disk Confocal Laser Microscope and two Leicester Advanced Imaging Facility (AIF) The Advanced Widefield Fluorescence Microscopes (Nikon/Andor) Imaging Facility (AIF) is the light microscopy facility of the form part of the Warwick Integrative Synthetic Biology College of Life Sciences at the University of Leicester. The Research Technology Facility (WISB RTF). facility offers a wide range of state if the art light microscope systems including label free imaging, high content screening, The three systems are set up to enable time-lapse whole slide scanning and confocal super resolution imaging over multiple days; with environment control microscopy. We provide support for sample preparation, chambers controlling heat and CO2 levels, a perfect focus user training, experimental setup including for FRAP, system to deal with focus drift and a motorised stage. The FLIP and FRET, CLEM (in collaboration with the Electron WISB RTF manager is happy to discuss the potential of Microscopy Facility (EMF)), and image analysis using ImageJ/ using these microscopes for your experiments. Fiji, Imaris and Huygens deconvolution. Personalized Fiji macros can be developed to analyse your image datasets.

UNIVERSITY OF WARWICK Key Contact: Sarah Bennett UNIVERSITY OF LEICESTER Email: [email protected] KEYWORDS: Telephone: 02476523927 KEYWORDS: Key Contact: Dr Kees Straatman Website: Email: [email protected] Fluorescence, Spinning Disk, Confocal, microscopy, WISB, https://www.wisb-uow. Fluorescence microscopy, whole slide scanning, label free imaging, Telephone: 0116 229 7085 Time-lapse, Nikon, Andor, Imaging co.uk/technology-facilities/ Twitter: @WISB_SynBioCtre confocal laser microscopy, live cell imaging, image analysis, training Website: https://le.ac.uk/cbs/facilities/aif

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WARWICK LATTICE COMPARE LIGHT SHEET

Our Wellcome-funded 3i Lattice LightSheet facility is open at The Centre of Membrane Proteins and Receptors (COMPARE) is a the University of Warwick. Six weeks per year are available multidisciplinary research centre that crosses the Universities of for visiting researchers and ongoing collaborations are Birmingham and Nottingham. COMPARE researchers use cutting welcome. The instrument uses a very thin, structured sheet edge technology, including advanced microscopy, to identify new of light to rapidly collect 4D movies of living cells. approaches for prevention and treatment of chronic conditions such as cardiovascular, metabolic diseases and cancer. At the Due to the thinness of the sheet, photo-bleaching and core of COMPARE is our advanced imaging facility, which is home photo-damage are minimised allowing capture of hundreds to multiple commercial and custom built microscopes together of image planes in a second and visualisation of dynamic with advanced tools for computational analysis. We provide processes inside cells in unprecedented detail. access, support and training in all our of technology including Our instrument is usually run in dithered mode giving super-resolution microscopy, single-particle tracking, light resolution of up to 230 x 230 x 370 nm (x x y x z) with 62.5x sheet microscopy, fluorescent correlation spectroscopy, FRET, magnification and an imaging depth up to 50 µm. The photometry and label-free imaging. system has 4 laser-lines and two cameras allowing truly simultaneous imaging. UNIVERSITIES OF BIRMINGHAM UNIVERSITY OF WARWICK AND NOTTINGHAM Key Contact: Helena Coker Key Contact: Deirdre Kavanagh (Birmingham) Email: [email protected] Other Contact: Joelle Goulding (Nottingham) KEYWORDS: Telephone: 024761 51934 KEYWORDS: Email: [email protected] Website: https://warwick.ac.uk/ Telephone: 0121 414 3325 CAMDU, Warwick, LLSM, Lattice, LightSheet, Microscopy, Light, camdu/microscopes/lattice/ Fluorescence, Microscopy, Super-Resolution, SIM, SMLM, STED, Website: https://www.birmingham- Sheet, Live Cell, Dynamics Twitter: @WarwickCAMDU Light-Sheet, Lattice, SPIM, FRET, Photometry, TIRFM, image analysis nottingham.ac.uk/compare/

SLIM / SCHOOL OF LIFE TECHNOLOGY HUB IMAGING SCIENCE IMAGING FACILITY, COLLEGE OF MEDICAL AND DENTAL SCIENCES

SLIM provides access to state-of-the-art microscopy from wide field, confocal, The Technology Hub Imaging Facility provides a diverse portfolio super resolution to electron microscopy supported by a team of 5 talented of imaging platforms including two point scanning confocal imaging specialists with a combined 100+ years expertise in microscopy, microscopes, an LSM780 and LSM880, both of which are equipped image-analysis and sample-preparation. for live cell imaging and time-lapse. The LSM880 is capable of fast super resolution imaging via the Airyscan detector. The creation The team are all Associate Fellows of the HEA and are very active in teaching of virtual slides through imaging of whole tissue mounts can be imaging theory and image analysis. The facility is available for collaborative achieved with the AxioScanZ.1 Slide Scanner using Histology, and service work both within University of Nottingham and externally. IHC and fluorescent stained samples. The PALM MicroBeam Laser Technology: Confocal Super resolution: STORM, PALM, SIM, STED TIRF Capture Micro-Dissection is the perfect precursor for proteomics High Content Imaging Label Free Microscopy FCS Luminescence Wide Field studies. Microscope access is via training using a blend of virtual Histology and sample processing Electron Microscopy Teaching: Workshops and in-person resources with independent booking rights granted. in imaging theory, post processing and image analysis.

UNIVERSITY OF NOTTINGHAM UNIVERSITY OF BIRMINGHAM Key Contact: Tim Self Key Contact: Rob Shaw Email: [email protected] Email: [email protected] KEYWORDS: Telephone: 0115 8230090 KEYWORDS: Telephone: 0121 414 9072 Website: https://www.nottingham.ac.uk/ Website: https://www.birmingham. Microscopy, Imaging, analysis, confocal, electron microscopy, histology life-sciences/facilities/slim/index.aspx Imaging Suite, Laser scanning, Wide field fluorescence microscopy, ac.uk/university/colleges/mds/facilities/ Twitter: @SLIM_Nottingham Live cell imaging, Slide scanning, Lightsheet microscopy technology-hub/imaging-facility.aspx

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CORE BIOTECHNOLOGY MIDLANDS REGIONAL SERVICES ELECTRON CRYO-EM FACILITY MICROSCOPY FACILITY

The EMF offers preparation, imaging and analysis of The Midlands Regional Cryo-EM Facility hosted at the Leicester Institute for biological samples for EM. The facility houses a TEM, SEM, Structural and Chemical Biology. Our Thermo Fisher Titan Krios G3 offers ultramicrotomes, coating unit, critical point dryer and wetlab. structural biologists the ability to answer important biological questions Staff are experienced in techniques including negative staining, by providing a complete workflow from sample to structure. The Krios is ultramicrotomy, immunogold labelling and SEM sample equipped with a Falcon 3 EC and K3 direct electron detectors and a Volta preparation and offer sample prep and advice for Correlative Phase Plate. This has yielded 3D reconstructions of 1.9Å on user projects Light and Electron Microscopy (CLEM) and 3D-EM (SBFSEM). and 1.7Å on ideal test specimens. Samples include viruses, proteins, nanoparticles, bacteria, Researchers can access equipment and support to complete a Cryo- cell cultures, tissues and model organisms and staff have EM project using either Single Particle Analysis (SPA) or Cryo-Electron experience with clinical biopsies, forensic material and CII & Tomography (Cryo-ET) and microscope access can be done on a completely CIII hazardous organisms. EMF staff are happy to discuss either remote basis or on site. We offer sample vitrificaton using either the industry a brief service or longer collaborative arrangements. Regular standard Thermo Fisher Vitrobot or a custom-made plunger with single- users are offered training. sided blotting and glow-discharging apparatus. Our High Performance Image Processing Facility completes the sample to structure workflow. UNIVERSITY OF LEICESTER Key Contact: Natalie Allcock UNIVERSITY OF LEICESTER KEYWORDS: Email: [email protected] Telephone: 0116 2523370 KEYWORDS: Key Contact: Christos Savva Transmission Electron Microscopy, TEM, Scanning Electron Website: www.le.ac.uk/cbs-em Email: [email protected] Microscopy, SEM, Ultramicrotomy, Critical Point Drying, Negative Twitter: @bioem_leicester Cryo-TEM, transmission electron microscopy, biological samples, Telephone: 0116 229 7109 staining, Immunolabelling, CLEM, Biological sample preparation Instagram: @bioem_leicester structure, single particle analysis, tomography Website: www.leicester.ac.uk/cryoem

ADVANCED THIN SECTION BIOIMAGING RTP LABORATORY

With two transmission electron microscopes and a range of The thin section labs have a range of cutting, mounting, sectioning preparatory equipment, the Advanced Bioimaging RTP at the and polishing equipment and resins to process a variety of materials. University of Warwick can analyse many different types of samples for various properties. We specialise in the analysis of biological samples Our laboratories offer standard and non-standard-sized polished from proteins, viruses and bacteriophage to the ultrastructure of thin sections and blocks for use in light and electron microscopy. cells, with techniques such as resin embedding and cryo-TEM. These methods also translate well to soft materials such as nanoparticles, vesicles, liposomes, where membrane thickness, particle size and general morphological characterisation are common requests. We are always happy to discuss projects so please contact us if you have any questions.

UNIVERSITY OF WARWICK UNIVERSITY OF LEICESTER Key Contact: Dr Saskia Bakker KEYWORDS: Email: [email protected] Key Contact: Annika Burns Telephone: 02476574095 KEYWORDS: Email: [email protected] Cryo-TEM, transmission electron microscopy, biological samples, Website: https://warwick.ac.uk/fac/sci/med/ Telephone: 0116 252 3792 cellular ultrastructure, nanoparticles, size measurements, negative research/bioimaging/whatwecando/ Thin sections, micromorphology, polished blocks Website: https://le.ac.uk/gge/services- stain, ultrathin sectioning Twitter: @strucbiowarwick for-business/facilities

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ROCK PREPARATION AND ELECTRON MICROSCOPY THIN SECTIONING FACILITY RESEARCH TECHNOLOGY PLATFORM

The Rock Preparation and Thin Sectioning Facility houses The Electron Microscopy suite at the University of Warwick cutting, drilling, crushing, powdering, polishing, sectioning is a Research Technology Platform primarily for materials and mounting equipment, capable of preparing a broad research, with particular emphasis on organic and inorganic range of geological materials. The Facility offers preparation semiconductors, functional ceramics, oxides, molecular of standard/polished thin sections in a range of sizes and electronic systems, two dimensional materials and nanotubes. mounting (resin/stub) of fine material for transmitted light/ electron microscopy. Additionally, the Facility offers core The RTP contains a wide range of microscopes including: 2 drilling of samples for palaeomagnetic analysis. high resolution scanning electron microscopes; Focused Ion Beam scanning electron microscope; 3 transmission electron microscopes from simple imaging and analysis to acquiring atomic resolution images and EDX /EELS analysis and 2 state-of-the-art scanning probe microscopes. Work can be performed by the RTP staff or we can provide training for self-use of equipment to provide maximum flexibility.

UNIVERSITY OF WARWICK Key Contact: Steve York UNIVERSITY OF BIRMINGHAM KEYWORDS: Email: [email protected] KEYWORDS: Telephone: 02476523391 Key Contact: Daniel Cox Electron Microscopy, Transmission Electron Microscopy, TEM, Scanning Website: https://warwick.ac.uk/fac/sci/physics/ Thin sections, Polished blocks, Stubs, Core drilling Email: [email protected] Transmission Electron Microscopy, STEM, Scanning Electron Microscopy, research/condensedmatt/microscopy/em-rtp/ Telephone: 0121 414 3619 SEM, Focused Ion Beam SEM Twitter: @RTP_Warwick

THE NANOSCALE AND ANALYTICAL SCANNING MICROSCALE RESEARCH ELECTRON MICROSCOPY AND CENTRE (NMRC) AUTOMATED MINERALOGY

The nmRC is an interdisciplinary facility at the University of Nottingham, The ZEISS Sigma 300 Analytical Scanning Electron dedicated to materials imaging and analysis, from microns to atoms, Microscope (SEM) joins a suite of other electron microscopes open to businesses and research organisations alike. With state-of-the- as part of the University of Leicester’s Advanced Microscopy art facilities allied to in-house technical and academic expertise, the Facility. The instrument is capable of supporting a wide Centre offers a diverse range of research and commercial capabilities. range of research applications and hosts a multitude of analytical detectors comprising two energy dispersive X-Ray We host a suite of over 20 instruments to facilitate imaging/analytical spectrometers (EDS), a wave length dispersive spectrometer investigation of materials including: Scanning and Transmission (WDS) and micro-XRF capabilities. Electron Microscopy (SEM/TEM), Focused Ion Beam SEM, Cryo- EM, Raman, X-ray photoelectron spectroscopy (XPS), Nanocluster This allows for a combination of high resolution imagery Fabrication, Electron Beam Lithography, ToF-SIMS with hybrid OrbiTrap with accurate and precise major and trace element chemical functionality, Electron Microprobe Analysis and Particle sizing. characterisation. This is specifically utilised in the automated analysis of materials particularly for mining and economic geology applications; including quantitative mineral phase identifications and proportions, element deportment and textural phase associations. UNIVERSITY OF NOTTINGHAM UNIVERSITY OF LEICESTER Key Contact: Craig Stoppiello Key Contact: Dr Tom Knott KEYWORDS: Email: [email protected] KEYWORDS: Email: [email protected] Telephone: 0115 748 6340 Telephone: 0116 252 3649 Nanomaterials, Surface Analysis, Imaging, Chemistry, Pharmacy, Website: https://www.nottingham.ac.uk/NMRC/ Scanning Electron Microscopy, EDS, WDS, micro-XRF, Automated Website: https://www2.le.ac.uk/ Engineering, TEM, SEM, XPS, Raman, CryoEM Lithography, OrbiSIMS Twitter: @UoNnmRC Mineralogy, Imaging, Materials colleges/scieng/research/lanser

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WMG ELECTRON X-RAY FLUORESCENCE MICROSCOPY SUITE SPECTROMETRY FACILITY (XRF)

The EMS@WMG is a department-centralised research platform, XRF is an analytical technique used to determine the elemental offering a range of advanced materials characterisation tools for composition of materials. The facility includes a fully equipped users within WMG, the University and beyond. sample preparation laboratory with powder pellet press, automated 4 position gas fusion bead maker, furnaces, drying ovens and It has complementary facilities to the other electron microscopy analytical balances supported by a crushing and milling facility. centres at Warwick and specialises in particular on the analysis of steels (full through the length scale chemical and crystallographic Our instrument laboratory consists of a WD-XRF which is used for the analysis) and battery materials (full airless transfer work flow). quantitative and qualitative analyses of samples to a high degree of precision and repeatability with concentrations down to 1ppm for The suite has 2 FEG-SEMs (with EDS, EBSD, WDS and various insitu some elements. There is also a handheld ED-XRF with a portable work mechanical stages), 2 dualbeam FIB-SEMs (with EBSD and SIMS) station for rapid analysis of samples, both lab based and in the field. and a Talos (S)TEM equipped with large angle EDS and Nanomegas PED. Other facilities include nanoindentation (with high and low temperature capabilities), Alicona IFM and micro-XRF.

UNIVERSITY OF LEICESTER UNIVERSITY OF WARWICK KEYWORDS: Key Contact: Lin Marvin Key Contact: Geoff West KEYWORDS: Email: [email protected] Scanning Electron Microscopy, Focused Ion Beam, (Scanning) / Email: [email protected] Telephone: 0116 2523817 Transmission Electron Microscopy, Precession Electron Diffraction, Telephone: 02476 573501 X-Ray Fluorescence spectrometer, pXRF, powder pellets, fusion Website: https://le.ac.uk/gge/services- X-ray Fluorescence Spectroscopy, Nanoindentation Website: https://warwick.ac.uk/fac/sci/wmg/ beads, analytical balances, furnaces, drying ovens for-business/facilities

KEELE UNIVERSITY CENTRAL X-RAY DIFFRACTION ELECTRON MICROSCOPE UNIT RTP

The central Electron Microscope Unit houses two JEOL transmission The X-ray diffraction RTP offers state-of-the-art X-ray scattering services, electron microscopes (TEM) and a Hitachi S4500 cold field emission primarily for material research. It is headed by the academic director, scanning electron microscope (FESEM). Professor Richard Walton and the facility manager, Dr David Walker. Our The high contrast, JEOL1230 TEM is ideal for biological electron team are highly knowledgeable and have multi-disciplined expertise. microscopy of ultrathin sections, although it has also been used for The RTP has powder XRD, high-resolution XRD, single-crystal XRD for magnetic nanoparticle and viral characterisation by negative staining, small molecule structural solution and a WDXRF system for elemental providing a simple approach to evaluate samples before imaging on analysis from B-U. A dedicated SAXS instrument is available for polymer high-end cryo-TEMs. The JEOL100CX has X-ray microanalysis attachment / nanomaterial research including liquid dispersed nanoparticles, gels, designed primarily for semi-thin section elemental analysis and mapping. powders and thin films (GISAXS). A wide range of services are available, The SEM is used for high resolution imaging, achieving better than 1.5 including phase ID, structural determination, lattice parameter nm resolution at 5 kV. It has been used for publications in high ranking determination, in-situ diffraction and more. journals and world leading textbooks such as Gray’s Anatomy. Example work includes biosynthetic materials and prostheses, microfossils and a wide range of biological samples.

UNIVERSITY OF WARWICK KEELE UNIVERSITY KEYWORDS: KEYWORDS: Key Contact: David Walker Key Contact: Simon Holborn X-ray Diffraction, XRD, SAXS, XRF, High-resolution, Scattering, Email: [email protected] Electron Microscopy, Transmission Electron Microscopy, TEM, Email: [email protected] powder XRD, Structural solution, nanomaterials, reflectivity, stress, Telephone: 024 76151299 Scanning Electron Microscopy, SEM Website: https://www.keele.ac.uk/emunit/ texture, GISAXS, non-ambient Website: www.warwick.ac.uk/go/x-ray

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CHEMISTRY X-RAY (LA)-ICP-MS CRYSTALLOGRAPHY

The School of Chemistry X-ray Crystallography Laboratory We operate a Thermo Scientific iCAP-Qc quadrupole ICP mass possesses five single crystal X-ray diffractometers and one spectrometer, for high-sensitivity measurement of trace powder X-ray diffractometer. Researchers within the School elements and isotope ratios in solutions and via laser ablation. of Chemistry can be trained to use the instruments whilst the Crystal Structure Service staff collect and analyse data for Solutions: Sample introduction is via a Cetac ASX-520 external users. AutoSampler, for analysis of chemically digested samples in an aqueous 2% nitric acid matrix. The single crystal diffractometers are equipped with CryoStreams for data collections in the temperature range Laser Ablation: Sample introduction is via a New Wave 80-500 K. The laboratory also possesses a Malvern PANalytical Research-ESI 213nm laser unit, fitted with a two-volume Xpert PRO powder diffractometer (Cu Ka1 monochromated ablation cell for in-situ analysis of a range of geological, source) setup to measure data in reflection mode (Bragg- engineering and archaeological materials. Brentano geometry) or in capillary mode. The powder diffractometer has an automatic sample changer for high throughput analyses. UNIVERSITY OF NOTTINGHAM UNIVERSITY OF LEICESTER Key Contact: Stephen Argent Email: [email protected] Key Contact: Adam Cox KEYWORDS: Telephone: 0115 7484065 KEYWORDS: Email: [email protected] Website: https://www.nottingham.ac.uk/chemistry/ Telephone: 0116 2523625 Crystallography, X-ray diffraction, single crystal, powder crystal research/research-infrastructure.aspx LA-ICP-MS, ICP-MS, laser, Inductively coupled plasma mass spectrometry, Website: https://le.ac.uk/gge/services- Twitter: @NottsChemistry trace elemental analysis for-business/facilities

WARWICK PHOTOEMISSION SCHOOL OF CHEMISTRY FACILITY MASS SPECTROMETRY AND CHROMATOGRAPHY

The Warwick Photoemission Facility provides advanced surface analysis We provide mass spectrometry and chromatography services via x-ray photoelectron spectroscopy (XPS), ultraviolet photoelectron to support synthesis and general analytical problem solving. spectroscopy (UPS), angle-resolved photoemission (ARPES) and low We run a suite of instruments with a wide variety of available energy electron diffraction (LEED). These techniques provide high ion-sources including ESI, APCI, MALDI, EI,CI, FD and FI precision composition, chemical state and electronic analysis of the ionisation techniques with GC-MS and LC-MS and solid probe surfaces of solid materials. inlets available. The Facility has two modern spectrometers available and can be a Equipment/Techniques Available: 1. Bruker ESI-TOF MicroTOF useful tool in research across the full spectrum of the sciences, including II open access high-res mass spectrometer 2. Bruker Impact II nanoparticles, biocatalysis, semiconductors, polymers, plastics, ultra-high resolution mass spectrometer UHPLC 3. photovoltaics, coatings, batteries, metallics, pharmaceuticals and more. Regular users can request hands on training both for using the Jeol AccuTOF GCX (TOF-MS) accurate mass GC-MS with range equipment and interpreting their data. of solid probes 4. Thermo single quad ITQ with Trace 1300 GC- MS with headspace sampler 5. Bruker Ultraflex III MALDI-TOF Mass Spectrometer.

KEYWORDS: UNIVERSITY OF WARWICK UNIVERSITY OF NOTTINGHAM X-Ray Photoelectron Spectroscopy, XPS, Ultraviolet Photoelectron Key Contact: Dr Marc Walker KEYWORDS: Key Contact: Ben Pointer-Gleadhill Spectroscopy, UPS, Surface Analysis, Surface Science, Surface Email: [email protected] Email: [email protected] Chemistry, Composition Analysis, Materials, Angle-Resolved Telephone: 02476 151776 Mass spectrometry, LC-MS, accurate mass, GC-MS, HPLC, MALDI, Telephone: 07896807334 Photoemission, ARPES, Low Energy Electron Diffraction, LEED Website: http://go.warwick.ac.uk/XPS electron ionisation Website: www.nottingham.ac.uk/analytical

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VOC AND GAS UK HIGH-FIELD SOLID-STATE ANALYSIS FACILITY NMR FACILITY

The facility houses a range of instruments for the analysis of The NMR National Research Facility (funded by EPSRC gases and vapours emanating of a range of sources including and BBRSC) hosted at Warwick is based around an food and drink, agriculture, manufactured parts and existing 850 MHz solid-state NMR spectrometer enabling biological samples (from humans or animals). applications across the physical and life science, including Capacity is available to test a large number of samples, as battery technology and energy materials, catalysts, well as being able to test more challenging form factors. pharmaceuticals, plant cell wall physiology and protein structural biology. The facility including three different electronic noses (instruments that replicate the biological olfactory system) The UK's first 1 GHz solid-state NMR spectrometer is in both a fixed laboratory and handheld formats, three FAIMS expected to be installed later in 2020. There are other solid- machines (including an autosampled version) and three GC- state NMR instruments located at Warwick, outside the IMS instruments (autosampled and direct analysis). National Research Facility, from 100 to 700 MHz, with a large array of probes for magic angle spinning (up to 111 kHz We also have ATD-GC-TOF-MS for chemical identification and spinning frequency) as well as static NMR and DOR. other portable gas analysers for off-site measurements.

UNIVERSITY OF WARWICK UNIVERSITY OF WARWICK Key Contact: James Covington KEYWORDS: Email: [email protected] KEYWORDS: Key Contact: Dinu Iuga (NRF Technical Director) Telephone: 07876877899 Email: [email protected] Electronic nose, Machine olfaction, gas analysis, VOC analysis, GC-MS, Website: www.warwick.ac.uk/go/BSL Solid-state NMR, Magic Angle Spinning (MAS), battery technology, Telephone: 024761 50814 headspace analysis, Portable VOC measurements Twitter: @WarwickEngineer pharmaceuticals, plant cell wall physiology, protein structural biology Website: warwick.ac.uk/go/850mhz

SCHOOL OF BIOSCIENCES NOTTINGHAM DNP FLAVOUR RESEARCH FACILITY MAS NMR FACILITY

The Food Flavour laboratory focuses on the identification and The DNP MAS NMR facility is the first and only commercial facility characterisation of complex food flavours. We have a unique interest of its kind in the UK, established at the University of Nottingham in understanding the real time release of aroma and taste compounds in 2015. The facility is open to external users and an application from food during oral processing. We are also experienced in evaluating scheme makes it possible for users to apply for instrument time the impact of trigeminal response (e.g., from capsaicin, carbonation, either for feasibility studies (pilot studies) or for full research etc.) on flavour release. We can analyse most samples due to our diverse projects through paid access. range of sample preparation techniques (static headspace, solid phase microextraction, direct liquid injection, thermal desorption and micro- The state-of-the-art technique increases the sensitivity of normal chamber). Current analytical equipment includes: E-tongue, HPLC/MS-MS; solid-state NMR by orders of magnitude and gives a unique insight 3 x GC-MS; GC-MS/MS, GC-O, TD-100, 2 x MS-NOSE APCI/MS-MS. We also into structures of a wide range of molecules covering energy provide analytical and consultancy support and both group and bespoke materials, catalysts, biomolecules, porous materials among others. training for the food and bioscience industries. We can give advise on the feasibility of experiments and can provide support for project design and planning, sample preparation, and data analysis.

UNIVERSITY OF NOTTINGHAM UNIVERSITY OF NOTTINGHAM Key Contact: Jenny Drury Email: [email protected] KEYWORDS: Key Contact: Subhradip Paul KEYWORDS: Telephone: 0115 951 6132 Email: [email protected] Website: www.nottingham.ac.uk/facts Nuclear Magnetic Resonance, Dynamic Nuclear Polarization, Telephone: 0115 7486278 Flavour, Aroma, Taste, Volatile Aroma Compounds, GC-MS, gas phase Twitter: @UoNFoodflavour Spectroscopy, Analytical Chemistry, Structural Studies, Catalysts, Website: https://www.nottingham. analysis, MS-NOSE, Real time release. LinkedIn: www.linkedin.com/company/uonflavour Energy materials, Biomolecules ac.uk/dnpnmr/home.aspx

32 33 TALENT Equipment Sharing Brochure

POLYMER CHARACTERISATION CRANFIELD FORENSIC RESEARCH TECHNOLOGY INSTITUTE (CFI) PLATFORM

We are a polymer and materials characterisation facility based at Cranfield University has recently invested £3.5 million in the the university of Warwick that exist to support research internally latest forensic science technology at its Cranfield campus in and externally. Our facility contains ~30 instruments that cover a Bedfordshire. Building on Cranfield’s distinctive strength in variety of polymer analysis needs. Our main specialities are GPC/ defence and security, this forensic science teaching and research SEC, thermal analysis (DSC, TGA, DMA) and particle sizing, however, facility is unparalleled in the UK and includes new facilities such many more instruments are available, including HPLC, GC and FTIR. as a virtual reality autopsy table, crime scene investigation rooms and a simulated mass grave excavation site. Equipment We offer many forms of service from single sample to bespoke at CFI includes: Inductively Coupled Plasma Mass Spectrometry design of analytical experiments. This includes discussions to (ICP-MS), Gas Chromatography (GC-MS), Portable X-Ray help devise the best course of action with respect to analytical Fluorescence (pXRF), Fourier-Transform Infrared Spectroscopy challenges. We also offer some bespoke synthesis requests. (FTIR), and laboratories dedicated to anthropology and archaeology, entomology, and mass spectrometry.

CRANFIELD UNIVERSITY UNIVERSITY OF WARWICK Key Contact: Stephanie Kimpton Key Contact: Daniel Lester Email: [email protected] Email: [email protected] Telephone: +44 (0)1234 750 111 x3328 KEYWORDS: Telephone: 02476574147 KEYWORDS: Website: https://www.cranfield.ac.uk/centres/ Website: https://warwick.ac.uk/services/ris/ cranfield-forensic-institute GPC, SEC, Gel Permeation Chromatography, Size Exclusion impactinnovation/impact/warwick-scientific- forensic science, archaeology, anthropology, entomology, LinkedIn: www.linkedin.com/school/cranfield-university Chromatography, Polymer Analysis, Polymer Characterisation, services/polymercharacterisation autopsy, crime scene investigation, digital forensics, Twitter: @CranfieldForSci TGA, DSC, DMA, Thermal Analysis, Materials Testing Twitter: @Polymer_RTP materials science, heritage crime Facebook: www.facebook.com/cranfieldforensicinstitute

MICRO-FOCUS WARWICK CENTRE FOR X-RAY COMPUTED ULTRAFAST SPECTROSCOPY TOMOGRAPHY AT WMG

The Micro-focus XCT facility provides high-resolution X-ray The Warwick Centre for Ultrafast Spectroscopy (WCUS) provides CT scanning capabilities to enable the 3D imaging of a wide a suite of spectroscopic techniques that examine how materials range of materials and geometries. respond after absorbing light on femtosecond (10^-15 s) timescales. Located in the Centre for Imaging, Metrology and Additive Our state-of-the-art laser experiments can probe electronic and Technologies (CiMAT) at WMG, and part of the EPSRC structural dynamics using ultraviolet (>235 nm) through to infrared National Research Facility for X-ray Computed Tomography, (<20 microns) light as well as in the terahertz regime. our facility has four CT scanners, ranging from a high power/ The techniques have been used to study light activated prodrugs high penetration system capable of scanning large metallic and sunscreens, as well as electron mobility, phase dynamics objects (e.g automotive engines and electric drive units), and beyond in novel materials (eg semiconductors, organic through to a lab grade ultra-high resolution system, capable electronics). “Steady-state” UV/visible/IR/THz absorption as well as of achieving resolutions of a few hundred nanometres, and photoluminescence techniques, allow us to fingerprint molecules a high speed CT system capable of 4D imaging of samples in before delving deeper with ultrafast study. dynamic states (eg under load in compression rigs).

UNIVERSITY OF WARWICK KEYWORDS: UNIVERSITY OF WARWICK Key Contact: Alex Attridge KEYWORDS: Email: [email protected] Ultrafast spectroscopy, terahertz spectroscopy, semiconductors, Key Contact: Michael Staniforth Telephone: 07887 682065 quantum materials, photostability, prodrugs and nanomedicine, Email: [email protected] X-ray Computed Tomography, NDT, Micro-focus XCT, High-power XCT, Website: https://warwick.ac.uk/fac/sci/wmg/ infrared spectrsocopy, ultraviolet spectroscopy, transient absorption Telephone: 02476 151013 In-situ scanning, Material characterisation, Digital imaging research/materials/metrology/about/ct/ spectroscopy, fluorescence spectroscopy Website: go.warwick.ac.uk/wcus

34 35 TALENT Equipment Sharing Brochure

SPECTROSCOPY RTP MULTI-USER ENVIRONMENT FOR AUTONOMOUS VEHICLE INNOVATION (MUEAVI)

The Spectroscopy RTP offers state of the art capabilities in MUEAVI is a £9 million ‘smart’ roadway test environment for Raman, photoluminescence (PL), optical absorption (UV-Vis the development of intelligent and autonomous vehicles (on and FT-IR) and Electron Paramagnetic Resonance. Diffraction and off highway, ground and airborne solutions), the first of limited imaging is available for Raman, PL and FT-IR. its kind in the UK next to an airport and within the controlled setting of a university campus. Individually or in combination these spectroscopic techniques is able to offer a non-destructive route for the identification It includes the associated systems needed to integrate and characterisation of a wide range of materials. emerging technologies into our day-to-day lives, encompassing vehicles, infrastructure, data, logistics, environment, sensors The facility can offer variable temperature experiments from and their implementation and management. 4 K to 1500 K across most techniques and provide bespoke experiments to meet specific needs. In the middle of the facility, within the Intelligent Mobility Engineering Centre (IMEC), there are vehicle workshops, Data can be either collected on your behalf and analysed vehicle electrification, autonomous vehicle, simulation, using specialist analysis packages by the facility staff; or for mechatronics and control systems laboratories. regular users hands on training can be provided. CRANFIELD UNIVERSITY Key Contact: Simon Stranks - Specialist UNIVERSITY OF WARWICK Technician for MUEAVI facility KEYWORDS: Email: [email protected] Key Contact: Ben Breeze Telephone: 01234 754675 or 754674 Intelligent and autonomous vehicles, mechatronics, simulation, KEYWORDS: Email: [email protected] Website: https://www.cranfield.ac.uk/facilities/mueavi intelligent mobility, urban and off-road environment, test track, Telephone: 02476 572 862 LinkedIn: https://www.linkedin.com/ infrastructure sensor development, traffic, instrumented vehicles, Optical Spectroscopy, Raman, FT-IR, UV-Vis, Electron Paramagnetic Website: https://warwick.ac.uk/research/rtp/spectroscopy school/cranfield-university/ advanced vehicle engineering, emerging technologies resonance EPR, Photoluminescence, Materials, Imaging Twitter: @RTP_Warwick Twitter: @CranfieldUni

WARWICK LASER AEROSPACE INTEGRATION MICROMACHINING RESEARCH CENTRE (AIRC)

Our laser machining facility consists of two Oxford The AIRC fosters collaboration between industry and academia Lasers systems: the E-Series (34 ns, 355 nm Nd:YAG) and and provides capabilities comparable with the leading aerospace the A-Series (15 ns, 532 nm Nd:YAG), both fitted with facilities across Europe and the world. high-resolution CNC stages. One of the AIRC’s unique features is its focus on integration, where These systems are capable of drilling, cutting and milling new aerospace technologies are rapidly developed and tested for a wide variety of materials with high precision. Macro/ current and future aircraft and airspace concepts. micrometer scale features can be machined in metals, plastics, composites, wafers, diamond. This is supported by centre-based facilities including our visualisation screens, flight simulators and air traffic management Applications include: sectioning wafers; cutting thin simulator which enable the development time from idea to metal sheets; milling surface features; mask fabrication; implementation to be shortened. machining complex geometries; surface roughening; materials that are difficult to machine by other methods. We have laboratories dedicated to aerial autonomous vehicles and engineering photonics and our 1500m2 open space laboratory enables research on full-scale aircraft and components. CRANFIELD UNIVERSITY Key Contact: James Fowler - Senior Technical Officer Email: [email protected] UNIVERSITY OF WARWICK Telephone: 01234 750111 ext: 5180 KEYWORDS: KEYWORDS: Website: https://www.cranfield.ac.uk/centres/ Key Contact: Claire Hurley aerospace-integration-research-centre Laser Micromachining, Drilling, Milling, Cutting, Composites, Email: [email protected] Aerospace technologies and integration, aircraft, airspace, flight LinkedIn: https://www.linkedin.com/ Polymers, Metal, Diamond, Mask Fabrication, Complex Geometries, Telephone: 024 7652 4603 simulators, air traffic management, air transportation, unmanned school/cranfield-university/ Surface Roughening Website: warwick.ac.uk/micromachining aerial vehicles, engineering photonics, intelligent automation Twitter: @CranfieldUni

36 37 TALENT Equipment Sharing Brochure

CRANFIELD IMPACT ENVIRONMENTAL CENTRE (CIC) ANALYTICAL FACILITY (EAF)

CIC is one of just two FIA (Federation Internationale de The EAF is utilised by research staff across the University l’Automobile) approved test centres in the world, used for (including environment, agrifood, water, energy and power) for crash-testing Formula One cars. chemical, biological and materials analysis. It is an internationally respected facility with expertise in It provides students and staff with first-class teaching and flexible vehicle crashworthiness and occupant simulation, conducting research facilities, offering a variety of analyses on a confidential leading research that provides highly effective solutions. and contract basis to a broad partner and client base. CIC is also an approved consultancy by the Vehicle External partners and businesses can utilise the EAF analytical Certification Agency (VCA) for both EC Regulation R66 coach services: a service providing bespoke analysis of environmental rollover Type Approval and R80 and can be used for sled samples; ideal for small numbers or occasional samples; analysis deceleration testing of structures and dummies, moment of carried out by experienced technical staff; competitively priced; inertia and centre of gravity measurement and finite element access to our academics’ expertise. modelling of accident reconstruction. CRANFIELD UNIVERSITY CRANFIELD UNIVERSITY Key Contact: James Watson - Cranfield Impact Centre Manager KEYWORDS: Key Contact: Richard Andrews Email: [email protected] Email: [email protected] Telephone: 01234 754149 Gas and liquid chromatography, metals analysis, wastewater analysis Telephone: 01234 750111 KEYWORDS: Website: https://www.cranfield.ac.uk/ and water treatment technologies, soil analysis, microbiology Website: https://www.cranfield.ac.uk/facilities/ facilities/cranfield-impact-centre and mycology, plant molecular biology, post harvest analytical environmental-analytical-facility Crash and impact testing, crashworthiness, vehicle safety, accident LinkedIn: https://www.linkedin.com/ techniques, environmental chemistry, membrane sciences, volatiles LinkedIn: https://www.linkedin.com/ reconstruction, vehicle engineering, lightweight structures and school/cranfield-university/ evaluation, algae growth and harvesting, small scale anaerobic school/cranfield-university/ materials, sled testing of structures and dummies Twitter: @CranfieldUni digestion, complete gas handling system Twitter: @CranfieldUni

GEOGRAPHY AND SOIL MANAGEMENT ENVIRONMENT FACILITY

The analytical laboratory within Geography and Environment The soil management facility provides a world-class at Loughborough University is equipped for the quantitative resource for the detailed study of interactions between assessment of chemical and physical properties of water, soils soil, crops/plants, water, agricultural machinery and and sediments from fluvial, glacial and aeolian environments. off-road vehicles. The facility allows controlled simulation of agricultural and environmental systems at the soil Equipment includes: Ion Chromatograph (IC) Total Organic aggregate to sub-field scale. Carbon (TOC) Analyser Laser Particle Sizer UV-Visible Spectrophotometer Freeze Drier Muffle Furnaces This facility is The equipment can also be used for product performance predominantly research based with technical staff supporting testing (eg agrochemical fate and efficacy; effectiveness of both teaching and research across a range of disciplines. erosion control technologies). For further information, queries or support please refer to our A soil erosion laboratory includes pressurised and gravity- contact information. fed rainfall simulators that simulate temperate and tropical rainfall, with realistic drop sizes, intensities and kinetic energies, for a range of return period storm events. CRANFIELD UNIVERSITY Key Contact: Ceri Dawson LOUGHBOROUGH UNIVERSITY Email: [email protected] Telephone: 01234 750111 ext. 5666 Key Contact: Sarah Wappat KEYWORDS: Website: https://www.cranfield.ac.uk/ Email: [email protected] facilities/soil-management-facility KEYWORDS: Soil management and erosion, crops, water, agricultural machinery, Telephone: 01509 222263 LinkedIn: https://www.linkedin.com/ off-road vehicles, agrochemicals, cultivation, sowing, rainfall, hydrological Geography, Soils, Sediment, Water Analysis, Ion Chromatography, Website: https://www.lboro.ac.uk/subjects/ school/cranfield-university/ processes, geotextiles, runoff, meteorological data, weeding, pesticides Total Organic Carbon (TOC), Laser Particle Sizer, Spectrophotometer geography-environment/facilities/ Twitter: @CranfieldUni

38 39 TALENT Equipment Sharing Brochure

NATIONAL RESEARCH WOLFSON SCHOOL FACILITY FOR WATER AND ELECTRONICS WORKSHOP AT WASTEWATER TREATMENT LOUGHBOROUGH UNIVERSITY

The National Research Facility for Water and Wastewater The Wolfson School Electronics Workshop has a wealth of technical Treatment provides UK researchers with the unique ability knowledge and equipment. to test, at scale, plants with real water. It is directly linked to Cranfield University’s 4,500 population equivalent sewage This includes experience in printed circuit board (PCB) design and treatment works and can also receive imported water. manufacture, programming micro-controllers, through to the design and manufacture of electrical cabinets, and additive manufacturing. The facility is supplied with compressed air, potable water and electricity with a total floor plan of 420m2 and height of 8.7m. Equipment includes, but not restricted to: The facility has ten modular bays for wastewater and eight - PCB Development and Etch Tanks modular bays for drinking water treatment projects. - PCB Drill and Router Recently upgraded with funding provided by UKCRIC, the facility - PCB Reflow Oven also now has dedicated drinking water treatment facilities with two near real scale pilot plants operating in parallel. Storage of As such, the Electronics Workshop is happy to provide design and up to 30m3 of drinking water is available for treatment. CRANFIELD UNIVERSITY manufacturing advice. Key Contact: Nigel Janes Email: [email protected] LOUGHBOROUGH UNIVERSITY Telephone: 01234 750111 ext. 3346 Website: https://www.cranfield.ac.uk/ Key Contact: Matt Biddulph (Electronics Technician) KEYWORDS: facilities/pilot-plant-hall-facility KEYWORDS: Email: [email protected] LinkedIn: https://www.linkedin.com/ Telephone: 01509 227540 Sewage treatment, drinking water treatment, wastewater, water school/cranfield-university/ Printed Circuit Board (PCB), Arduino, Micro-Controllers, Website: https://www.lboro.ac.uk/ science, pilot facility, water monitoring and testing Twitter: @CranfieldUni Electrical Cabinets, CAD, Ultimaker departments/meme/about/facilities/

WARWICK THERMAL CRANFIELD ORDNANCE ENERGY FACILITY TEST AND EVALUATION CENTRE (COTEC)

The Warwick Thermal Energy Facility consists of a range of COTEC performs independent test and evaluation on munitions, thermal analysis and testing equipment. The facility includes the weapon systems, pyrotechnic and explosive stores, and conducts Thermal Properties Laboratory, containing a suite of materials disposals and demilitarisation, although its extensive range analysis equipment for various techniques: thermogravimetric facilities are suitable for testing other materials and equipment. analysis (TGA), high-pressure calorimetry (DSC), dilatometry (TMA) and conductivity measurements (XFA, GHP). COTEC is situated on the edge of Salisbury Plain and is part of Cranfield University, academic provider to the UK Defence We also have facilities suitable for testing larger prototypes Academy at Shrivenham. including the Large Solar Simulator, Environmental Chambers and the ThermExS Laboratory. COTEC is licensed by the MoD and other organisations and is accredited to EN ISO 9001:2008. Facilities at COTEC also We work alongside the Warwick Sustainable Thermal Energy allow the testing of non-explosive items (for example, rapid Technologies research group, who have extensive expertise decompression). Customers include the UK MoD, the Defence in developing a wide range of low-carbon heating and cooling Science and Technology Laboratory, the Atomic Weapons CRANFIELD UNIVERSITY technologies. For a full range of equipment visit our website. Establishment, commercial defence suppliers and manufacturers. Key Contact: Trevor Lawrence Email: [email protected] Telephone: 01380 813251 UNIVERSITY OF WARWICK KEYWORDS: Website: https://www.cranfield.ac.uk/centres/ centre-for-defence-chemistry/cranfield- KEYWORDS: Key Contact: Jake Locke Defence and security, firing range, munitions testing, ammunition ordnance-test-and-evaluation-centre Email: [email protected] proofing, ordnance proofing, explosive trials, bullet and fragment LinkedIn: https://www.linkedin.com/ Thermal Analysis, Materials Testing, Thermal Conductivity, Calorimetry, Telephone: 02476575187 attack, fragmentation trials, testing and evaluation, flare test track, school/cranfield-university/ Dilatometry, Sorption, Solar Simulator, Humidity, Heating and Cooling Website: http://www.warwick.ac.uk/stet high altitude test facility, pyrotechnics Twitter: @CranfieldUni

40 41 TALENT Equipment Sharing Brochure

SCIENTIFIC COMPUTING KEELE UNIVERSITY SMART RESEARCH TECHNOLOGY ENERGY NETWORK PLATFORM (SC RTP) DEMONSTRATOR

The SC RTP provides a Linux-based shared infrastructure for The Keele University Smart Energy Network Demonstrator (SEND) is the research computing. We manage a Linux research computing largest at-scale multi-vector smart energy demonstrator in Europe, delivered environment deployed to hundreds of PCs and workstations in partnership with Siemens, Cadent and ENGIE, and funded through the and also accessible via remote desktop. European Regional Development Fund and the Department for Business, Energy and Industrial Strategy. As well as intelligent power distribution, The RTP hosts Warwick’s High Performance Computing (HPC) renewable production and storage, our gas network is critical to SEND, and clusters for batch processing of computationally intensive HyDeploy is a green energy network trial aimed at kick starting the low- workflows, such as large-scale simulations, high throughput carbon hydrogen economy. HyDeploy at Keele is being delivered by Cadent, parameter searches and analysis of large datasets. This is with Northern Gas Networks, Progressive Energy Ltd, Keele University, HSE housed in a recently refurbished machine room. and ITM Power. Our Research Software Engineering (RSE) team provide Together SEND and HyDeploy enables ‘at scale’ research opportunities in training and consultancy as well as more direct support via intelligent energy generation, distribution, storage, forecasting and multi- secondment to research projects. Please see our website for vector balancing across our campus ‘living laboratory’ providing an ‘at scale’ hardware specifications. research and development opportunities. With 100 homes and 30 faculty buildings and over 13,000 staff and students, Keele provides the testbed for UNIVERSITY OF WARWICK the future of the energy infrastructure underpinning the UK’s path to net zero. KEELE UNIVERSITY Key Contact: Dr Matt Ismail Email: [email protected] Key Contact: Sidrah Khan, SEND KEYWORDS: and [email protected] KEYWORDS: Programme Delivery Manager Telephone: 07896807334 Email: [email protected] Scientific Computing, Research Computing, Research Software Website: https://warwick.ac.uk/research/rtp/sc Smart Energy Network Demonstrator, Intelligent Energy Generation, Telephone: 01782 732964 Engineering, High Performance Computing, Linux Twitter: @RTP_Warwick Living Laboratory Image credits: Keele Uni/Siemens

CENTRE FOR MATHEMATICAL COGNITION

The CMC is a dedicated research centre within the School of Science with access to small adaptable areas, various equipment and expertise. Our facility and areas of application are multi- purpose and include covering subjects of Maths, Psychology, Education, Physiology as well as others. Measures of equipment include various formats of eye-tracking, psychophysiology, virtual reality, multi-touch table, permanent and portable observation. We welcome any related enquiries via the contact information.

LOUGHBOROUGH UNIVERSITY Key Contact: Aatif Patel KEYWORDS: Email: [email protected] Telephone: 01509 227172 Eye-tracking (VR, remote and mobile); Psychophysiology Website: https://www.lboro.ac.uk/research/cmc/ (fixed and mobile GSR, ECG, EMG), Observation (fixed and mobile) Twitter: @lborocmc

42 43 GLOSSARY:

ACCIDENT RECONSTRUCTION CELL SORTING ELECTRICAL CABINETS GAS AND LIQUID CHROMATOGRAPHY CRANFIELD IMPACT CENTRE (CIC) 38 WISB FLOW CYTOMETRY AND CELL SORTING FACILITY 08 WOLFSON SCHOOL ELECTRONICS WORKSHOP AT LOUGHBOROUGH ENVIRONMENTAL ANALYTICAL FACILITY (EAF) 39 UNIVERSITY OF NOTTINGHAM FLOW CYTOMETRY FACILITY 08 UNIVERSITY 41 AEROSPACE TECHNOLOGIES AND INTEGRATION GC-MS, GAS PHASE ANALYSIS UNIVERSITY OF BIRMINGHAM FLOW CYTOMETRY PLATFORM 09 AEROSPACE INTEGRATION RESEARCH CENTRE (AIRC) 37 ELECTRON MICROSCOPY SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 CLEM SLIM / SCHOOL OF LIFE SCIENCE IMAGING 22 AGRICULTURAL MACHINERY GC-MS CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 SOIL MANAGEMENT FACILITY 39 KEELE UNIVERSITY CENTRAL ELECTRON MICROSCOPE UNIT 28 SCHOOL OF CHEMISTRY MASS SPECTROMETRY AND CHROMATOGRAPHY 31 CONFOCAL MICROSCOPY VOC AND GAS ANALYSIS FACILITY 32 AGROCHEMICALS BIRMINGHAM ADVANCED LIGHT MICROSCOPY (BALM) 21 ELECTRON PARAMAGNETIC RESONANCE (EPR) SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 PLANT GROWTH FACILITY 16 SLIM / SCHOOL OF LIFE SCIENCE IMAGING 22 SPECTROSCOPY RTP 36 GEL PERMEATION CHROMATOGRAPHY (GPC) ANTIMICROBIAL SCREENING CONFOCAL LASER MICROSCOPY ELECTRONIC NOSE POLYMER CHARACTERISATION RESEARCH TECHNOLOGY PLATFORM 34 (ANTIMICROBIAL RESISTANCE) ADVANCED IMAGING FACILITY 21 VOC AND GAS ANALYSIS FACILITY 32 WARWICK ANTIMICROBIAL SCREENING FACILITY 10 GENOMICS AUTOMATED HIGH-THROUGHPUT LIQUID HANDLING AND CRASH AND IMPACT TESTING ENTOMOLOGY LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 MICROBIOREACTOR PLATFORMS 11 CRANFIELD IMPACT CENTRE (CIC) 38 CRANFIELD FORENSIC INSTITUTE (CFI) 35 DEEP SEQ: NEXT GENERATION SEQUENCING FACILITY 11

ANTHROPOLOGY CRIME SCENE INVESTIGATION EYE-TRACKING HAZARD GROUP 3 ORGANISMS CRANFIELD FORENSIC INSTITUTE (CFI) 35 CRANFIELD FORENSIC INSTITUTE (CFI) 35 CENTRE FOR MATHEMATICAL COGNITION 42 CONTAINMENT LEVEL 3 (C3) FACILITY 10

ARCHAEOLOGY CRYO-TEM FLAVOUR HEADSPACE ANALYSIS CRANFIELD FORENSIC INSTITUTE (CFI) 35 ADVANCED BIOIMAGING RTP 24 SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 VOC AND GAS ANALYSIS FACILITY 32 MIDLANDS REGIONAL CRYO-EM FACILITY 25 AROMA FLIGHT SIMULATORS HERITAGE CRIME SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 AEROSPACE INTEGRATION RESEARCH CENTRE (AIRC) 37 CRANFIELD FORENSIC INSTITUTE (CFI) 35 DATA ANALYSIS AUTOMATION FLOW CYTOMETRY (FACS) HIGH PERFORMANCE COMPUTING AUTOMATED HIGH-THROUGHPUT LIQUID HANDLING AND BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 WISB FLOW CYTOMETRY AND CELL SORTING FACILITY 08 SCIENTIFIC COMPUTING RESEARCH TECHNOLOGY PLATFORM (SC RTP) 42 MICROBIOREACTOR PLATFORMS 11 DIGITAL DROPLET PCR UNIVERSITY OF NOTTINGHAM FLOW CYTOMETRY FACILITY 08 HPLC AUTOPSY LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 UNIVERSITY OF BIRMINGHAM FLOW CYTOMETRY PLATFORM 09 SCHOOL OF CHEMISTRY MASS SPECTROMETRY AND CHROMATOGRAPHY 31 SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 CYTOF AND BIRMINGHAM FLOW CYTOMETRY 09 DIGITAL FORENSICS STEMLAB BIOSUITE 14 ILLUMINA BIOINFORMATICS CRANFIELD FORENSIC INSTITUTE (CFI) 35 LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 DEEP SEQ: NEXT GENERATION SEQUENCING FACILITY 11 FLUORESCENCE MICROSCOPY DISSOLUTION TESTING BIOINFORMATICS RESEARCH TECHNOLOGY PLATFORM 17 ADVANCED IMAGING FACILITY 21 IMAGE ANALYSIS HEALTH AND LIFE SCIENCES 15 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 FLUORESCENCE SPECTROSCOPY ADVANCED IMAGING FACILITY 21 DNA BIOINFORMATICS TRAINING WARWICK CENTRE FOR ULTRAFAST SPECTROSCOPY 35 IMAGING FLOW CYTOMETRY LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 FLUORESCENT LIGHT MICROSCOPY (FLUORESCENCE) UNIVERSITY OF NOTTINGHAM FLOW CYTOMETRY FACILITY 08 DNA EXTRACTION BIOMARKERS ADVANCED IMAGING TECHNOLOGIES 20 INDUCTIVELY COUPLED PLASMA MASS LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 PHENOME CENTRE BIRMINGHAM 17 BIRMINGHAM ADVANCED LIGHT MICROSCOPY (BALM) 21 SPECTROMETRY (ICP-MS) DNA SEQUENCING COMPARE 23 (LA)-ICP-MS 31 BLOOD CELL COUNTER TECHNOLOGY HUB IMAGING FACILITY, COLLEGE OF MEDICAL AND BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 SCHOOL OF SPORT, EXERCISE AND HEALTH SCIENCES 15 DENTAL SCIENCES 23 INSTRUMENTED VEHICLES DRUG DISCOVERY MULTI-USER ENVIRONMENT FOR AUTONOMOUS VEHICLE INNOVATION BRAIN FOCUSED ION BEAM SEM (MUEAVI) 37 WARWICK ANTIMICROBIAL SCREENING FACILITY 10 ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 ELECTRON MICROSCOPY RESEARCH TECHNOLOGY PLATFORM 27 DYNAMIC NUCLEAR POLARIZATION+A:N WMG ELECTRON MICROSCOPY SUITE 28 INTELLIGENT AND AUTONOMOUS VEHICLES BULLET AND FRAGMENT ATTACK MULTI-USER ENVIRONMENT FOR AUTONOMOUS VEHICLE INNOVATION NOTTINGHAM DNP MAS NMR FACILITY 33 CRANFIELD ORDNANCE TEST AND EVALUATION CENTRE (COTEC) 41 FORENSIC SCIENCE (MUEAVI) 37 EEG CRANFIELD FORENSIC INSTITUTE (CFI) 35 CALORIMETRY INTELLIGENT ENERGY GENERATION ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 WARWICK THERMAL ENERGY FACILITY 40 FT-IR KEELE UNIVERSITY SMART ENERGY NETWORK DEMONSTRATOR 43 CENTRE FOR HUMAN BRAIN HEALTH 13 SPECTROSCOPY RTP 36

44 45 GLOSSARY:

ION CHROMATOGRAPHY MICROBIOLOGY ROBOTIC SCREENING NEUROELECTROPHYSIOLOGY PROTEOMICS (POST-TRANSLATIONAL MODIFICATION) GEOGRAPHY AND ENVIRONMENT 38 (HIGH THROUGHPUT) ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 PROTEOMICS RESEARCH TECHNOLOGY PLATFORM 19 WARWICK ANTIMICROBIAL SCREENING FACILITY 10 NEUROELECTROPHYSIOLOGY AND ORGAN BATH ADVANCED MASS SPECTROMETRY FACILITY AT THE LABEL FREE IMAGING AUTOMATED HIGH-THROUGHPUT LIQUID HANDLING AND PHARMACOLOGY LABORATORY 12 UNIVERSITY OF BIRMINGHAM 20 ADVANCED IMAGING FACILITY 21 MICROBIOREACTOR PLATFORMS 11 BIOINFORMATICS RESEARCH TECHNOLOGY PLATFORM 17 NEXT GENERATION SEQUENCING LASER MICROMACHINING MICROBIOREACTOR DEEP SEQ: NEXT GENERATION SEQUENCING FACILITY 11 PYROTECHNICS WARWICK LASER MICROMACHINING 36 AUTOMATED HIGH-THROUGHPUT LIQUID HANDLING AND LEICESTER GENOMICS CORE FACILITY (NUCLEUS) CRANFIELD ORDNANCE TEST AND EVALUATION CENTRE (COTEC) 41 MICROBIOREACTOR PLATFORMS 11 LASER PARTICLE SIZER NMR SPECTROSCOPY QPCR GEOGRAPHY AND ENVIRONMENT 38 MICROMORPHOLOGY LEICESTER INSTITUTE OF STRUCTURAL AND CHEMICAL BIOLOGY 18 LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 THIN SECTION LABORATORY 25 UK HIGH-FIELD SOLID-STATE NMR FACILITY 33 LATTICE LIGHTSHEET RAMAN NOTTINGHAM DNP MAS NMR FACILITY 33 WARWICK LATTICE LIGHT SHEET 22 MICROSCALE THERMOPHORESIS THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 LABEL FREE BIOMOLECULAR INTERACTION ANALYSIS 14 LIVE CELL IMAGING NON-INVASIVE BRAIN STIMULATION SPECTROSCOPY RTP 36 ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 ADVANCED IMAGING FACILITY 21 MICROSCOPY REAL TIME RELEASE STEMLAB BIOSUITE 14 OMIC ANALYSIS SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 LIVING LABORATORY ADVANCED IMAGING TECHNOLOGIES 20 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 KEELE UNIVERSITY SMART ENERGY NETWORK DEMONSTRATOR 43 BIRMINGHAM ADVANCED LIGHT MICROSCOPY (BALM) 21 RECOMBINANT PROTEIN PRODUCTION IN BACTERIAL OPTICAL SPECTROSCOPY PROTEIN EXPRESSION FACILITY (PEF) 19 LOW ENERGY ELECTRON DIFFRACTION (LEED) WARWICK LATTICE LIGHT SHEET 22 SLIM / SCHOOL OF LIFE SCIENCE IMAGING 22 SPECTROSCOPY RTP 36 WARWICK PHOTOEMISSION FACILITY 30 RESEARCH SOFTWARE ENGINEERING CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 ORBISIMS SCIENTIFIC COMPUTING RESEARCH TECHNOLOGY PLATFORM (SC RTP) 42 MAGIC ANGLE SPINNING (MAS) ADVANCED BIOIMAGING RTP 24 THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 UK HIGH-FIELD SOLID-STATE NMR FACILITY 33 MIDLANDS REGIONAL CRYO-EM FACILITY 25 RNA NOTTINGHAM DNP MAS NMR FACILITY 33 COMPARE 23 ORGAN BATH PHARMACOLOGY LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 TECHNOLOGY HUB IMAGING FACILITY, COLLEGE OF MEDICAL AND NEUROELECTROPHYSIOLOGY AND ORGAN BATH MALDI DENTAL SCIENCES 23 PHARMACOLOGY LABORATORY 12 RNA SEQUENCING SCHOOL OF CHEMISTRY MASS SPECTROMETRY AND CHROMATOGRAPHY 31 THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 PILOT FACILITY ELECTRON MICROSCOPY RESEARCH TECHNOLOGY PLATFORM 27 MASK FABRICATION NATIONAL RESEARCH FACILITY FOR WATER AND RNA EXTRACTION ANALYTICAL SCANNING ELECTRON MICROSCOPY AND WARWICK LASER MICROMACHINING 36 WASTEWATER TREATMENT 40 LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 AUTOMATED MINERALOGY 27 MASS SPECTROMETRY WMG ELECTRON MICROSCOPY SUITE 28 PLANT AND ROOT PHENOTYPING SCANNING ELECTRON MICROSCOPY (SEM) PROTEOMICS RESEARCH TECHNOLOGY PLATFORM 19 KEELE UNIVERSITY CENTRAL ELECTRON MICROSCOPE UNIT 28 PLANT GROWTH FACILITY 16 CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 ADVANCED MASS SPECTROMETRY FACILITY AT THE UNIVERSITY OF THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 BIRMINGHAM 20 MICRO RNA PLANT GROWTH (SOIL-CROP SYSTEMS) ELECTRON MICROSCOPY RESEARCH TECHNOLOGY PLATFORM 27 (LA)-ICP-MS 31 LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 PLANT GROWTH FACILITY 16 ANALYTICAL SCANNING ELECTRON MICROSCOPY AND AUTOMATED SCHOOL OF CHEMISTRY MASS SPECTROMETRY AND CHROMATOGRAPHY 31 MITOCHONDRIAL PROFILING PLATE READERS MINERALOGY 27 VOC AND GAS ANALYSIS FACILITY 32 WMG ELECTRON MICROSCOPY SUITE 28 MITOCHONDRIAL PROFILING CENTRE 16 STEMLAB BIOSUITE 14 KEELE UNIVERSITY CENTRAL ELECTRON MICROSCOPE UNIT 28 MATERIALS SCIENCE MODELS OF INFECTION PRINTED CIRCUIT BOARD (PCB) CRANFIELD FORENSIC INSTITUTE (CFI) 35 CONTAINMENT LEVEL 3 (C3) FACILITY 10 WOLFSON SCHOOL ELECTRONICS WORKSHOP SEQUENCING AT LOUGHBOROUGH UNIVERSITY 41 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 MEG MRI ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 PROTEIN EXPRESSION SEWAGE TREATMENT CENTRE FOR HUMAN BRAIN HEALTH 13 CENTRE FOR HUMAN BRAIN HEALTH 13 PROTEIN EXPRESSION FACILITY (PEF) 17 NATIONAL RESEARCH FACILITY FOR WATER AND WASTEWATER TREATMENT 40 METABOLICS MS-NOSE PROTEIN PRODUCTION PHENOME CENTRE BIRMINGHAM 17 SINGLE CELL (SINGLE CELL CLONING) SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 PROTEIN EXPRESSION FACILITY (PEF) 17 UNIVERSITY OF NOTTINGHAM FLOW CYTOMETRY FACILITY 08 MICROARRAY MUNITIONS TESTING PROTEIN-PROTEIN INTERACTIONS LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 SINGLE CELL GENOMICS CRANFIELD ORDNANCE TEST AND EVALUATION CENTRE (COTEC) 41 LABEL FREE BIOMOLECULAR INTERACTION ANALYSIS 14 BIOINFORMATICS ANALYSIS SUPPORT HUB (BASH) 18 LEICESTER INSTITUTE OF STRUCTURAL AND CHEMICAL BIOLOGY 18 NANOINDENTATION WMG ELECTRON MICROSCOPY SUITE 28

46 47 GLOSSARY:

SINGLE CELL GENOMICS TRANSCRIPTOMICS THIN SECTIONS X-RAY DIFFRACTION (XRD) LEICESTER GENOMICS CORE FACILITY (NUCLEUS) 12 THIN SECTION LABORATORY 25 X-RAY DIFFRACTION RTP 29 POLYMER CHARACTERISATION RESEARCH TECHNOLOGY PLATFORM 34 ROCK PREPARATION AND THIN SECTIONING FACILITY 26 CHEMISTRY X-RAY CRYSTALLOGRAPHY 30

SLED TESTING OF STRUCTURES AND DUMMIES TIRF X-RAY FLUORESCENCE (XRF) CRANFIELD IMPACT CENTRE (CIC) 38 BIRMINGHAM ADVANCED LIGHT MICROSCOPY (BALM) 21 WMG ELECTRON MICROSCOPY SUITE 28 X-RAY FLUORESCENCE SPECTROMETRY FACILITY (XRF) 29 SLEEP LAB TISSUE CULTURE X-RAY DIFFRACTION RTP 29 ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 STEMLAB BIOSUITE 14 X-RAY PHOTOELECTRON SPECTROSCOPY (XPS) SMALL ANGLE X-RAY SCATTERING (SAXS) TMS THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 X-RAY DIFFRACTION RTP 29 ASTON INSTITUTE OF HEALTH & NEURODEVELOPMENT 13 WARWICK PHOTOEMISSION FACILITY 30 SMALL SCALE ANAEROBIC DIGESTION TOTAL ORGANIC CARBON (TOC) ENVIRONMENTAL ANALYTICAL FACILITY (EAF) 39 GEOGRAPHY AND ENVIRONMENT 38

SMART ENERGY NETWORK DEMONSTRATOR TRAINING KEELE UNIVERSITY SMART ENERGY NETWORK DEMONSTRATOR 43 ADVANCED IMAGING FACILITY 21

SOIL MANAGEMENT AND EROSION TRANSIENT ABSORPTION SPECTROSCOPY SOIL MANAGEMENT FACILITY 39 WARWICK CENTRE FOR ULTRAFAST SPECTROSCOPY 35

SOLAR SIMULATOR TRANSMISSION ELECTRON MICROSCOPY (TEM) WARWICK THERMAL ENERGY FACILITY 40 CORE BIOTECHNOLOGY SERVICES ELECTRON MICROSCOPY FACILITY 24 ADVANCED BIOIMAGING RTP 24 SOLID-STATE NMR MIDLANDS REGIONAL CRYO-EM FACILITY 25 UK HIGH-FIELD SOLID-STATE NMR FACILITY 33 THE NANOSCALE AND MICROSCALE RESEARCH CENTRE (NMRC) 26 NOTTINGHAM DNP MAS NMR FACILITY 33 ELECTRON MICROSCOPY RESEARCH TECHNOLOGY PLATFORM 27 SPINNING DISK WMG ELECTRON MICROSCOPY SUITE 28 ADVANCED IMAGING TECHNOLOGIES 20 KEELE UNIVERSITY CENTRAL ELECTRON MICROSCOPE UNIT 28

SPR ULTRAFAST SPECTROSCOPY LABEL FREE BIOMOLECULAR INTERACTION ANALYSIS 14 WARWICK CENTRE FOR ULTRAFAST SPECTROSCOPY 35

S2 AND MAMMALIAN CELLS ULTRASOUND PROTEIN EXPRESSION FACILITY (PEF) 19 SCHOOL OF SPORT, EXERCISE AND HEALTH SCIENCES 15

TABLET PREPARATION ULTRAVIOLET PHOTOELECTRON SPECTROSCOPY HEALTH AND LIFE SCIENCES 15 (UPS) WARWICK PHOTOEMISSION FACILITY 30 TABLET TESTING HEALTH AND LIFE SCIENCES 15 VOC ANALYSIS VOC AND GAS ANALYSIS FACILITY 32 TASTE SCHOOL OF BIOSCIENCES FLAVOUR RESEARCH FACILITY 32 VOLATILE AROMA COMPOUNDS School of Biosciences Flavour Research Facility 32 TEST TRACK MULTI-USER ENVIRONMENT FOR AUTONOMOUS WATER ANALYSIS VEHICLE INNOVATION (MUEAVI) 37 GEOGRAPHY AND ENVIRONMENT 38 ENVIRONMENTAL ANALYTICAL FACILITY (EAF) 39 THERMAL ANALYSIS (TGA AND DSC) NATIONAL RESEARCH FACILITY FOR WATER AND POLYMER CHARACTERISATION RESEARCH TECHNOLOGY PLATFORM 34 WASTEWATER TREATMENT 40 WARWICK THERMAL ENERGY FACILITY 40 WHOLE SLIDE SCANNING ADVANCED IMAGING FACILITY 21

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