Receptor-type tyrosine-proteinMuscle- skeletal receptor phosphatase tyrosine kinase S Dual specificity mitogen-activated protein kinase kinase 1 Plasminogen activator inhibitor-1 Epidermal growth factor receptor erbB1 Beta amyloid A4 protein

MAPDual specificity Epidermalkinase mitogen-activated growth factorCasein proteinreceptor ERK2 kinase and ErbB2kinase; II (HER1 alphaMEK1/2 and (prime) HER2)

Casein kinase II alpha alpha-IIb MAPCasein kinase kinase II beta ERK1 Dual specificity mitogen-activated protein kinase kinase 2

Integrin alpha-IIb/beta-3 Furin Mitogen-activatedSerine/threonine-protein kinase RAF and Dual specificityEpidermal protein mitogen-activated growth proteinkinase; factor kinase kinase receptor 1 (Raf/MEK)ERK1/ERK2 Integrin alpha-V/beta-3 Integrin alpha-V/beta-3 and alpha-IIb/beta 3 Casein kinase II Signal transduction by Integrin alpha-V/beta-6

Casein kinase II alpha/beta Vitronectin receptor alpha Bone morphogenetic protein 2 ECM proteoglycans Bone morphogenetic protein 4 VitronectinElastic fibre formation Peripheral plasma membrane protein CASK -1

Integrin alpha-V/beta-5 Protein kinaseProtein kinase C (PKC) alpha Integrin alpha-2/beta-3 Molecules associated with elastic fibres PKC alpha and beta-2 MER intracellular domain/EGFR extracellular domain chimera Fibronectin receptor alpha Protein kinase C- PKC; classical/novel Syndecan interactions

Integrin alpha-2 von Willebrand factorIntegrin alpha-10 Laminin interactions Integrin alpha-11

Fibrinogen beta chain

Serine/threonine-proteinVascular endothelial growth factor receptor 2 kinase PAK 1 Vascular endothelial growth factor receptorPlatelet Adhesion to exposed collagen Integrin alpha-1 Tyrosine-protein kinase Lyn CD44 antigen Integrin cell surface interactionsCHL1 interactions Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 Tyrosine-protein kinase FYN Integrin alpha-5/beta-1 Integrin alpha-V/beta-1Ras-related C3 botulinum toxin substrate 1 Oxidized low-density lipoprotein receptor 1 T-cell surface antigen CD2 Other semaphorin interactions Thrombin and coagulation factor VII TRAIL receptor-1 Leukocyte common antigen

Fibronectin matrixFibronectin formation receptor beta Glycophorin-A Integrin alpha-4/beta-1 factor 4

HLA-DR antigens-associated invariant chain Transforming growth factor beta-1 Integrin alpha2/beta1 Apolipoprotein B-100 CellP- glycoproteinsurface ligand 1 interactions at theIntegrin vascular alpha-4 wall migration inhibitory factor Thrombin and coagulation factor X Fibronectin Vitamin K-dependentP-selectin protein C Integrin alpha-4/beta-7 Localization of the PINCH-ILK-PARVIN complex to focal adhesions Integrin alpha1/beta1Fibronectin receptor (Integrin complexalpha-5/beta-1 and alpha-V/beta-3) MIF/CD74 (Macrophage migrationLymphocyte Proto-oncogeneinhibitory factor and HLA-DR function-associated tyrosine-protein Leukocyteantigens-associated kinaseinvariant chain) MER antigen 3- adhesionCD58 glycoprotein LFA-1 alpha Serine/threonine-protein kinase ILK-1 Selectin E MET interacts with TNS Tumor necrosis factorThrombin receptor superfamily member 10B MET activates PTK2 signaling Integrin alpha-3

Leukocyte adhesion molecule-1 Smooth Muscle Contraction Hepatocyte growth factor receptor Triggering receptor expressed on myeloid cells 1

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 Paxillin Cell division control protein 42 homolog Tyrosine-proteinFocal adhesion kinase SRC kinase 1

Serine/threonine protein phosphataseAurora 2A- kinase B/Inner 56 centromere kDa protein regulatory subunit- alpha isoform Serine/threonine-proteinMyosin chain kinasekinase- smoothPAK 2 muscle RHO GTPases Activate Formins CD22 40S ribosomal protein S27 Antigen-presenting glycoprotein CD1d Calmodulin Serine/threonine protein phosphatase 2A- catalytic subunit- alpha isoform IntercellularCD81 antigen adhesion molecule (ICAM-1)- Integrin alpha-L/beta-2 Annexin A2 Integrin alpha-M/beta-2 Centromere-associated protein E Annexin A2/S100-A10 Serine/threonine-protein kinase PLK1 Pulmonary surfactant-associatedComplement protein C3D Tubulin beta-1 chain High affinity immunoglobulin gamma Fc receptor IIntegrin alpha M Integrin alpha-L/beta-2 (LFA-1) interactions Mitotic checkpoint serine/threonine-protein kinase BUB1 Hemagglutinin Segment polarity proteinSerine/threonine dishevelled protein phosphatase homolog PP1-gamma catalytic subunitDVL-2 HLASH2 class domain-containing I histocompatibility protein 1A antigen A-3 Serine/threonine-proteinTubulin kinase TAO1 beta-2 chain

Basic fibroblast growth factor Tubulin beta-3 chainTransformingKinetochore protein RhoA protein NDC80 homolog Segment polarity protein dishevelled homolog DVL-1 Intercellular adhesion molecule-1 Exportin-1 Serine/threonine-protein kinase Aurora-B Vascular protein 1 Segment polarity protein dishevelled homolog DVL-3 Actin- cytoplasmic 1 Myelin-associated glycoprotein Rho-related GTP-binding protein RhoB Heat shock cognate 71 kDa protein Sodium/potassium-transporting ATPase Kinesin-likeTubulin protein KIF2C Hepatocyte growth factor Monocarboxylate transporter 1 Cystine/glutamate transporter Monocarboxylate transporter 4 L-type amino acid transporter 1 Cyclophilin A

Collagenase Matrix metalloproteinase-1Baculoviral IAP repeat-containing protein 5

Hypoxia-inducible factor 1 alpha Opioid receptors; delta & kappa Serine/threonine-protein kinase AKT Induced myeloid leukemia cell differentiation protein Mcl-1 Delta opioidSerine/threonine-protein receptor kinase PIM1 Heme oxygenase 1 Tumour suppressor p53/oncoprotein Mdm2 PI3-kinase p85-alpha subunit Signal transducer and activator of transcription 1-alpha/beta PI3-kinase class I Interleukin-4 and 13 signalingEotaxin Forkhead box protein O3 CCR5/mu opioid receptor complex Mu opioid receptorInterleukin-6 Opioid receptors; mu & delta Platelet glycoprotein 4 Opioid receptors; mu & kappa Interleukin-8 JAK3/JAK1 Monoamine oxidase CyclooxygenaseCellular tumor antigen p53

JAK2/TYK2 Homeobox protein NANOG Bcl-xL/BAK 5-lipoxygenase/FLAP Tumour suppressor protein p53/Mdm4 TNF-alpha Sphingosine 1-phosphate receptor Edg-1 Nuclear receptor ROR-alpha Matrix metalloproteinase 9 JAK2/JAK1Myc proto-oncogene protein PI3KCDK-interacting p110 protein beta/p85 1 alpha Apoptosisc-Myc/Max regulator Bcl-X Tyrosine-protein kinase JAK2 VascularArachidonate endothelial growth factor A 15-lipoxygenase JAK1/JAK2/TYK2 HeatCoagulation shock factor XIIINitric oxide protein sythases;PI3-kinase iNOS p110-alpha/p85-alpha HSP90 & nNOS Cyclin-dependentPI3-kinase p110-delta/p85-alpha kinaseCDK6/cyclin 4/cyclin D1 D1 Interleukin-1Heat shock protein beta HSP 90-alpha Cyclooxygenase-2 Opioid receptors; mu/kappa/delta ImmunoglobulinSignal epsilon transducer Fc receptor and activator of transcription 6 Forkhead box protein O1 JAK1/TYK2 Endoplasmin ApoptosisTyrosine-protein regulator Bcl-2 Nuclear receptor ROR-gamma kinase TYK2 G1/S-specific cyclin D1 C-C motif chemokine 2 Matrix metalloproteinase-2 Cyclin-dependentSignalPOU domain- transducer class 2- transcription factor 1 and kinase activatorHypoxia inducible of4/cyclin factors; transcription HIF-1-alpha- HIF-2-alpha D 3 AKT/p21CIP1 Tyrosine-protein kinase JAK3 Matrix metalloproteinase 3

Tyrosine-proteinArachidonate 5-lipoxygenase kinase JAK1 Monoamine IL6Ralpha/GP130oxidase A Nitric oxideCREB-binding protein/p53 synthase- inducible