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BMJ Open: first published as 10.1136/bmjopen-2020-048042 on 23 June 2021. Downloaded from BMJ Open is committed to open peer review. As part of this commitment we make the peer review history of every article we publish publicly available. When an article is published we post the peer reviewers’ comments and the authors’ responses online. We also post the versions of the paper that were used during peer review. These are the versions that the peer review comments apply to. The versions of the paper that follow are the versions that were submitted during the peer review process. They are not the versions of record or the final published versions. They should not be cited or distributed as the published version of this manuscript. BMJ Open is an open access journal and the full, final, typeset and author-corrected version of record of the manuscript is available on our site with no access controls, subscription charges or pay-per-view fees (http://bmjopen.bmj.com). 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Downloaded from Risk factors, symptom reporting, healthcare-seeking behaviour and adherence to public health guidance: protocol for Virus Watch, a prospective community cohort study ForJournal: peerBMJ Open review only Manuscript ID bmjopen-2020-048042 Article Type: Protocol Date Submitted by the 22-Dec-2020 Author: Complete List of Authors: Hayward, Andrew; University College London, Institute of Epidemiology and Health Care Fragaszy, Ellen; University College London, Centre for Public Health Data Science, Institute of Health Informatics; LSHTM, Department of Infectious Disease Epidemiology Kovar, Jana; University College London, Institute of Epidemiology and Health Care Nguyen, Vincent; University College London, Institute of Epidemiology and Health Care; University College London, Centre for Public Health Data Science, Institute of Health Informatics Beale, Sarah; University College London, Institute of Epidemiology and http://bmjopen.bmj.com/ Health Care; University College London, Centre for Public Health Data Science, Institute of Health Informatics Byrne, Thomas; University College London, Centre for Public Health Data Science, Institute of Health Informatics Aryee, Anna; University College London, Centre for Public Health Data Science, Institute of Health Informatics Hardelid, Pia; University College London, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health Wijlaars, Linda; UCL, Population, Policy and Practice; University College on September 29, 2021 by guest. 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London, Primary Care and Population Health Fong, Wing Lam Erica; University College London, Centre for Public Health Data Science, Institute of Health Informatics Geismar, Cyril; University College London, Institute of Epidemiology and Health Care; University College London, Centre for Public Health Data Science, Institute of Health Informatics Patel, Parth; University College London, Centre for Public Health Data Science, Institute of Health Informatics Shrotri, Madhumita; University College London, Centre for Public Health Data Science, Institute of Health Informatics Navaratnam, Annalan M D; University College London, Institute of Epidemiology and Health Care; University College London, Centre for Public Health Data Science, Institute of Health Informatics Nastouli, Eleni ; Francis Crick Institute; University College London, Department of Population, Policy and Practice Spyer, Moira; Francis Crick Institute Killingley, Ben; University of Nottingham School of Medicine; University College London Hospital For peer review only - http://bmjopen.bmj.com/site/about/guidelines.xhtml Page 1 of 21 BMJ Open BMJ Open: first published as 10.1136/bmjopen-2020-048042 on 23 June 2021. 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Downloaded from 1 2 3 4 Risk factors, symptom reporting, healthcare-seeking 5 6 behaviour and adherence to public health guidance: protocol 7 8 for Virus Watch, a prospective community cohort study 9 10 11 Andrew Hayward1, Ellen Fragaszy2,3, Jana Kovar1, Vincent Nguyen1,2, Sarah Beale1,2, Thomas 12 Byrne2, Anna Aryee2, Pia Hardelid4, Linda Wijlaars4, Wing Lam Erica Fong2, Cyril Geismar1,2, 13 14 Parth Patel2, Madhumita Shrotri2, Annalan M D Navaratnam1,2, Eleni Nastouli5,6, Moira Spyer6,, 15 7,8 9 9 10 11 16 Ben Killingley , IngemarFor Cox peer, Vasileios Lamposreview,Rachel A onlyMcKendry , Yunzhe Liu , Tao 17 Cheng11, Anne M Johnson13, Susan Michie12, Jo Gibbs13, Richard Gilson13, Alison Rodger13,14, 18 19 Robert W Aldridge2 20 21 22 Affiliations 23 24 25 26 1 Institute of Epidemiology and Health Care, University College London, London, UK 27 2 Centre for Public Health Data Science, Institute of Health Informatics, University College 28 29 London, UK. 30 3 Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical 31 32 Medicine, Keppel Street, London, UK. http://bmjopen.bmj.com/ 33 34 4 UCL Great Ormond Street Institute of Child Health, London, UK. 35 5 Department of Population, Policy and Practice, UCL Great Ormond Street Institute of Child 36 37 Health, London, UK. 38 6 Francis Crick Institute, London, UK. 39 40 7 Health Protection and Influenza Research Group, Division of Epidemiology and Public Heath, on September 29, 2021 by guest. 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