The NIH Record

U.S. Department February 26 National of Health 1985 Institutes and Vol. XXXVI of Human Services No. 5 Health

Commemorative Stamp Dr. Robert Gallo and 3 Japanese Scientists Honors NIMH Scientist Share Hammer Prize for Cancer Research Or. Robert C Gallo, chief of the laboratory of Tumor Cell Biology In the National Cancer Institute, has been awarded the 1984 Ham­ mer Foundation Cancer Research prize along with three Japanese scientists. Or Gallo was awarded $50.000-half the $100,000 prize- and three other scientists will share the remainder. The three Japanese scientists are: Yorio Hinuma, professor al the lnslllule for Virus Research. Kyoto University: lsao Miyoshi, Koch1 Medical School: and K1yosh1TakatsukI. Nobel Prize winner Dr. Julius Axelrod of the Kumamoto University School of Medicine. National Institute of Mental Health is the first NIH The award was presented Feb. 11 at a scientist to be honored on a Swedish Postage luncheon In Los Angeles by Dr. Armand Ham­ Stamp. He shares the honor with two other scientists, Prof. Ulf von Euler of Sweden and Sir mer, chief executive of the Occidental Petro­ Bernard Katz of England. The three men were leum Corporation who is currently serving a awarded the Nobel Prize in Medicine or third term as chairman of the President's Can­ Physiology in 1970 for their independent research cer Panel. into the chemistry of nerve transmission. The independent work of the award recipi- Dr. Gallo CONSENSUS CONFERENCE ents and their subsequent collaboration has established a direct causal relationship be­ Avoid Drugs to Prevent Travelers' Diarrhea; tween the adult T-cell leukemia virus and Prompt Treatment Is Best and Safer Method adult T-cell leukemia, Or. Hammer indicated. In presenting the award, Dr. Hammer By Judy Murphy added: "The work of these distinguished sci­ entists Is important because for some years It An NIH consensus panel recently advised days in bed. and restricted act1v1ty has been known that certain tumor viruses travelers against taking medication to prevent Tourists traveling beyond their nations' bor­ can cause naturally occurring leukemias and diarrhea while traveling abroad. Rather. It rec­ ders spend more than $100 billion annually. lymphomas in a number of animal species ommended that antibiotics or certain over­ The economic costs of travelers' diarrhea are Until the time of the discoveries we are recog­ the-counter products be used tor rapid relief therefore substantial due not only to medical nizing today, none of these tumor viruses of symptoms after they occur. limiting diar­ costs but also lo lost tourist dollars. Fear of ill­ causing leukemias and lymphomas in animals rhea in most cases to 30 hours or less. ness is reported to be a ma1or deterrent to had been linked to human leukemias and More than one-third of the 8 million Ameri­ travel in developing countries. lymphomas. cans visiting developing countries each year A number of antibiotics are available today "It was In 1979 that Dr. Gallo's laboratory develop diarrhea, the most common health that can prevent or ameliorate travelers' diar­ isolated the first human leukemia virus from problem encounterd by these travelers. rhea. but questions have been raised as to the T lymphocytes of certain forms of adult The consensus conference on travelers' di­ whether the benefits outweigh the risks inher­ leukemias and lymphomas. The virus was first arrhea, held at NIH Jan. 28-30, was spon­ ent In the use o1 such drugs, which medica­ found 10 an American patient, and later 10 sored by the National Institute of Allergy and tions are effective. and whether the drugs close association with clusters of similar can­ Infectious Diseases and the Office of Medical should be used as prophylaxis or treatment. cers in southwestern Japan. Applications of Research The meeting was The panel concluded that treatment begun attended by more than 250 epidemiologists. early after the onset of symptoms and contin­ "The work of Dr. Gallo, Dr. Hinuma, Or. gastroenterologists. representatives of the uing for 2 to 3 days Is preferable to the pro­ Miyoshi and Dr Takatsuki is providing new Armed Forces, and members of the travel in­ phylactic (preventive) use of antibiotics, and valuable insights into the nature of the dustry, among others. Participants heard which requires a 2- to 3-week course of the devasting group of diseases we call cancer. presentations by experts in diarrheal disease, drug and increases the risk of adverse drug It is an impressive example of dedication, including travelers' diarrhea. reactions. persistence and hard work combined with Travelers' diarrhea is caused by a wide The symptoms of travelers' diarrhea include scientific insight. range of infectious agents transmitted primar­ a twofold or greater increase in frequency of "Another very significant aspect of the re­ ily through contaminated food or water. Al­ unformed bowel movements, abdominal search, .. Or. Hammer continued. "is the fact though it is rarely life-threatening, travelers' diarrhea can cause considerable discomfort, (See TRAVELER'S D, Page 9) (See GALLO, Page 11) OMS Director Leaves NIH; Joins Nat'I Health Services :The NIH Record Dr. Julio Rivera, director of the NIH Occu­ pational Medical Service, Division of Safety, left NIH Feb. 1 to join the National Health 'Pubhshed biweekly at Bethesda. Md, by lhe Edi10, 1al Opera­ Services Inc. hons Branch, 0 1v1s1on of Public Information, for the inlormallon of employees ol the Nahonal lnstuules of Health, Department of Before coming to NIH. Dr. Rivera had , Health and Human Services, and circulated by request to writers served as an occupational medical officer for and to researchers in b1omed1cal and related fields The content the Navy for 20 years in a program which fo­ 1s reprmtable w1tnou1 pe,miss,on Pictures may be available on request. cused on the medical and health implications associated with submarine, diving, industrial, The NJH Record reserves the right lO make correcuons, environmental. hospital, and radiological changes. or deletions in submitted copy in conformity wllh 1he pohcies of the paper and HHS. exposures. He was attracted to the position as the di­ NIH Record Office rector of OMS because of the technical over­ Bldg. 31, Room 28-03, Phone 496-2125 lap between the occupational medicine pro­ gram at NIH and the Navy, the broad range ol Editor Herschel Cribb responsrbrflties, the large staff .and the com­ plex variety of potential hazards rn every NIH job c lassification. Staff Writer• Edltorlal AHl ■t■ nl Joyce F. McCarthy Marilyn Berman The knowledge and experience gained at Anne Barber Navy was an invaluable resource when he and his colleagues at OMS began designing Staff Corre-1pondenta medical surveillance programs for NIH work­ Dr. Rivera CC, A,chard McMaous; DCAT. Joan P Sooel; DPM, Harri ers exposed to asbestos, PCB, ethyloxide and respond to the myriad ol technical prob­ Marshall DRG. Sue Meado ws ORA, Barbara Menick; DRS. J,m Doherly. FIC, Susan P Slark, NCI Patricia A Newman NEI. and chemical carcinogens. lems concerning fire, chemical, occupational Marsha Corbett NHLBI, Larry Blaser, NIA Claire McCullough Among notable achievements In medical and environmental salety. NIAIO, Jeanne W1nnick, N1ADOK, Eileen Comgan NICHO James Hadley NIDA. Jody Dove NIEHS, Hugh J Lee; NIGMS. Wanda surveillance program design and implemen­ The second event was OMS' move to the Warddell; NIMH Mqnlyo Sargent N INCDS, Carol Rowan. NLM tation spearheaded by Dr. Rivera and his col­ ACRF In Bldg. 10. Because of its proximity to A0ger L Gilkeson, leagues at OMS was the development of a Clinical Center clinicians, OMS enjoyed a program to monitor chemical carcinogens broad exchange of ideas and technical ex­ which accompanies the NIH medical surveil­ pertise. In turn. Dr. Rivera offered his exper­ TRAINING TIPS lance program and guidelines. This model tise by serving on several CC committees program has been adopted and implemented such as the Infection Control and, the CC The fol lowing courses are sponsored by the Divi­ sion of Personnel Management, Development and by numerous other government agencies as Safety and Disaster Planning Committee. Training Operations Branch. well as by the private sector Dr. Rivera will serve as a senior consultant Dr. Rivera names two significant events in occupational medicine for the National Course during his career at NIH which lostered his Health Services Inc. which currently provides Admmistrat1ve Systems Starts Dead/me continued interest in practicing occupational the contract service for OMS. Dr. Rivera will (Call 496-6211) medicine at NIH. continue to consult with NIH's OMS through Basic Time & Attendance 4/11 3/28 The fi rst occurred when OMS administra­ cflnical and administrative troubleshooting. Delpro (for new users only) 4/8 3/25 tively joined the Division of Safety in 1981 . Dr Barbara Wasserman, previously assist­ This allowed for greater technical exchange TechmcaltOccupat1onal ant medical director for OMS. will now serve Related Training (Call 496-6211 ) between the various OS branches which see as medical director. D Computer Literacy for 3/12 2/21 Secretaries and Office Support or Personnel 3/14 2/21 Barcodes on NIH ID Cards To Replace Library Cards Programs (Call 496-6211) Adult Education Program NIH Library cards are now being replaced Training and Oevelopmenc Services Program The card, with a memorandum of permission, by barcodes attached to the back of NIH ID may be given to NIH staff doing library work for cards. Execucive, Management the cardholder. but the staff person will also be and Supervisory (Call 496-6371 ) The NIH Library is making the c hange as required to show his/her NIH identification part of the new automated cIrculation/catalog card. Any questions about this procedure Commun1cat1on Issues 3/26 3/8 system that will go into operation soon. Cur­ Supervising in the Federal should be directed to the head of the circula­ Wage System 3/ 11 2/22 rent NIH Library cards will be Invafld rn that tion unit ( 496-5611 ) Supervising the Clerical & system. New applicants for NIH Library privileges Support Staff 3/25 3/8 To expedite the change, library staff mem­ should continue to apply at the circulation Capitol Hill Workshop 3/25 3/8 bers are available at a table near the circula­ desk. Introduction to Supervision 4/1 3115 tion desk Feb. 25-Mar. 22. Monday through Managing Advisory Committee 4/8 3/15 Friday, 8:30 a.m. to 5 p.m., ready to attach Overdue Items Manage Your Meetings 4/ 15 3129 barcodes to ID cards of current NIH Library Effective Communications 4116 3/29 Library staff and the NIH Library Advisory cardholders. Committee have agreed on two procedural White House Workshop 4125 4/8 If you wish to continue as a library Effective Presentations Skills 4122 415 changes on overdue items. These changes ap­ cardholder. please bring m your current NIH 512 4/5 pear in a list of "Library Privileges and Respon­ 516 4/5 ID according to the following schedule sibil1t1es" distributed to patrons as they receive Last Name Week to Report their barcoded ID card. Chamber Orchestra Concert, A thru F Feb. 25-Mar. 1 The two new procedures are as follows G thru J Mar. 4-8 • Overdue notices are sent 7 days, 21 days, Mar. 9 K thru M Mar. 11-15 and 84 days after an item is due The third no­ The R&W Chamber Orchestra will present a N thru Z Mar 18-22 tice will also be sent to the borrower's concert featuring Meir Rimon, princ ipal horn If you are unable to visit the library at the supervisor. of the Israel Philharmonic, on Saturday. scheduled time, feel free to ask tor a barcode • A borrower with six overdue items. or one Mar. 9. at 3 p.m. , in the Masur Auditorium. at any time there is no line at the table. overdue item recalled for another borrower. will Bldg. 10, Clinical Center Buy tickets at The barcoded NIH ID is not translerrable to not be permitted to borrow until the overdue R&W. □ non-NIH personnel to obtain library services. material has been returned □

Page 2 The NIH Record February 26, 1985 NIH Police Crack Down On Unpaid Tickets, Fines NIH employees are advised to pay their SECURITY WATCH parking tickets promptly. Recently Congress passed a bill enabling magistrates of U.S. Dis­ ■ OFFICE ■ LABORATORY D OTHER trict Courts nationwide to collect an additional ■ HOSPITAL D PERSONAL $25 assessment fee from any individual found guilty of a misdemeanor or criminal act. The fee New Access Rules Adopted for ACRF Garage will be assessed for all failures to pay parking tickets or other violations which occurred after To Improve Security After Hours, Holidays, Etc. Oct. 12, 1984. The NIH Division ol Safety in collaboration The interior barriers separating the P-1 and The $25 fee will benefit victims of crime acts with the Clinical Center has been studying P-2 levels. and the P-2 and P-3 levels. will also under the Federal Victim Relief Fund estab­ ways to improve security measures in and be removed at 7 p.m. to allow vehicles lished by the Comprehensive Crime Control Act around the CC and the Ambulatory Care Re­ uninterrupted travel throughout all three levels of 1984, Public Law 98-473, Chapter XIV, Vic­ search Facility. There has been particular con­ ol the garage. tims of Crime Act 1984. cern about uncontrolled access to the ACRF At 6 a.m., Monday through Friday, the gates The assessment fee can be avoided by garage at night. will be opened and the interior barriers paying the fine within the 15 days after Beginning Monday, Mar. 4, the following replaced. receiving the violation, or by paying it prior to changes will be made to improve security and On weekends and holidays, the only vehicu­ appearing before a magistrate. If these options protection: lar entrance to the garage will be at the P-3 are ignored and the individual fails to appear in All vehicles entering or exiling the ACRF ga­ level. via Memorial Rd There will be no interior court. he or she may be faced with the follow­ rage between 7 p.m. and 6 a.m .. Monday barriers separating the three levels of the ga­ ing consequences: through Friday. and weekends and holidays. rage during those times. • An increase in the original fine. After 15 must do so at the P-3 entrance. via Memorial As a result of the changes described above, days, the f1nee is scheduled to appear ,n court. Rd .. at the east end of the garage. The Police all vehicles entering or exiting the ACRF ga­ If he/she fails to appear. the original fine dou­ booth at the P-3 entrance will be staffed 24 rage after the usual working hours will travel di­ bles. If that fine is not paid. a warrant tor arrest hours a day, rectly past the Police booth. A police officer will Is issued and the fine is tripled. The warrant At 7 p.m .. Monday through Fnday, the P-1 be present to monitor vehicles, and to provide must be satisfied immediately or the person entrance located at the west end of the garage assistance and information as necessary. could be picked up by the U.S. Marshal, trans­ from Convent Dr , and the P-2 entrance. lo­ For add1t1onal inlormat1on, contact the NIH ported to Baltimore, and jailed. cated at the east end of the garage from Me­ Police Section, Bldg 31 . Rm. B1A04, • No receipt of vehicle reg 1strat1on applica­ morial Rd . will be closed by chain link gates. , 496-5685. D tion. If the original fine for the misdemeanor (parking ticket) Is not paid, the registration ap­ New Publication Started plication for that individual ,s flagged by the Motor Vehicle Administration, and that person On NIH Security Issues LOCKII .. will not receive a vehicle registration application. A new publication which will deal with secu­ According to the office of Magistrate James rily issues at NIH has been announced by the Protection and Security Management Branch J. Lombardi. U.S. District Court. Baltimore. who presides over the Bethesda 1urisd1ction, there of the Division of Safety OD/ORS. "Security are more warrants issued at NIH than at any Watch" will be published monthly and distrib­ other station in the state. Capt. Howard S. Dav­ uted desk to desk. enport, NIH Police, says there are currently 20 The objective of Security Watch is to inform warrants for arrest issued for NIH NIH employees how to take preventive action employees. D on security problems occurring in the office. laboratory. and hospital. Practical advice is given on how an employee can prevent secu­ E, F and G Parking Permits rity problems. or if one occurs, how to handle Must Be Renewed in March the problem. and where it should be reported. The first issue of Security Watch entitled, General parking permits for NIH employees "Equipment in the Office or laboratory" ex­ whose last name begins with E, F, or G must plains how to better secure office, laboratory be renewed during March. and hospital equipment Employees may renew parking permits any The Division ol Safety and PSMB welcomes workday at the NIH Parking Office. Bldg. 31, your interest in security issues at NIH. To sug­ Rm. B1C19. between 8:30 a.m and 3 pm. gest topics for future issues of Security Watch Parking permits will also be available as and the poster program, call 496-2801 O follows: • Blair Bldg., Wednesday, Mar. 13. 1 to 2 p.m.. Con!. Rm. 110 FAES Offers 30 Grants of $500 • Federal Bldg., Wednesday, Mar 20, 1 to For Summer Student Research 2 p.m. , Con!. Rm. 8119 • landow Bldg , Wednesday, Mar. 20. 2:30 The FAES will award 30 grants of $500 STEP Presents Seminar, Mar. 14 to 3:30 p.m., Conf Rm. C each to students conducting research al the • Westwood Bldg., Wednesday, Mar. 13, 9 NIH th is summer. High school, undergradu­ The Staff Training in Extramural Programs to 11 a.m .. Cont. Rm. 3 ate, graduate and medical students who work Committee will present Module 1-Seminar IV Affected employees will receive a memo for a minimum of 8 weeks are eligible. on computer capabilities and program admin- about the upcoming renewal providing spe­ Applications are available in the FAES ol­ 1strat1on In the lister Hill Auditorium. cific instructions to obtain replacement per­ fice, Bldg 10. Rm. 2C207 A. Completed appli­ Bldg. 38A. on Th ursday, Mar. 14. from 1 30 to mits. Employees with preferential (red) or cations including a description of the re­ 4:30 p.m. carpool parking permits whose last name be­ search to be performed and the supporting No advance registration is required. regis­ gins with E. F, or G need not obtain new park­ statement from the NIH sponsor must be re­ tration will begin at 1 p.m. All extramural staff ing permits during March. ceived by Apr. 1 Awards will be made May are Inv1ted to attend. New March general parking permits must 1. □ For add1t1onal information. call 496-1493. [J be displayed beg1nn1ng Monday. Apr. 1. D

February 26, 1985 The NIH Record Page 3 ries for salad bar toppings and other special NIH Will Observe March as National Nutrition Month entrees will also be posted in all of the NIH With Emphasis on 'Ways and Whys of Weight Control' cafeterias on campus. A special seminar on "Body Weight and Health" will be given by Dr. Artemis P. Simopoulos, NCC chairman. on Friday, Mar 8, in Bldg. 31 . Cont. Rm. 9, 12-1 p.m. The "N IH-NCC Nutrition Research Exhibit" will be on d'1splay at the ACRF Visitors Center. Copies of the NIH pamphlet, Nutrition Re• search at the National Institutes of Health will be available at the exhibit site. All nutrition pamphlets currently available to the public from the various Institutes will be displayed for pickup at the publications area of the Visitors Center

Diet Contest OMS, with the assistance of the NCC Sub­ committee on Nutrition Education. is also planning to sponsor a "Weight Loss Competi­ tion" among various Institutes and Divisions beginning in April Details on this competition will be available during March through OMS to all interested persons. Plan to attend National Nutrition Month ac­ tivities and learn more about the "ways and As part of the "Resolutions" campaign sponsored by the Woodward and Lothrop stores, the "Eat whys of weight control." Get help in shedding Well, Be Well II" series was shown at all 16 stores during January. Karen A. Donato (I), an NIH nutri­ those extra pounds that may have accumu­ tionist and cochairperson of the NIH-Nutrition Coordinating Committee·s Subcommittee on Nutrition lated during the long winter months. D Education, was present at a number of stores in order to answer any questions on the nutrition in­ formation in the videotapes, and to offer samples of the featured recipes. Photo by Sally Dunkerson Dieting is an obsession for many Americans Bldg. 1, Wilson Hall, Thursday. Mar. 14, 11 :30 Pediatric Branch Sponsors Benefit but national surveys indicate that obesity is a.m. and 12:15 p.m.: Bldg. 38A. Rm. B1N30B. For 'Kids at the NCI', Mar. 16-17 still widely prevalent among both children and Thursday, Mar. 14, 11 .30 a.m. and 12:15 adults p.m.'; Federal Bldg., Rm. 8119, Wednesday. The Pediatric Branch, National Cancer In­ Activities planned for March-National Nu­ Mar. 20, 11 :30 a.m. • stitute. will sponsor Katherine Mizell's Model- trition Month-at NIH will emphasize proper ('NIH Fitness center personnel will present ways to lose weight (diet and exercise) and a special seminar on the importance of exer­ explain reasons why maintaining a "desirable cise at these sessions.) weight" is important. "Dangerous Dieting": ACRF Visitor Center, -<;Katlte,a,r,e;.§711.1;,el!/!l>--. ­ NIH-supported investigators have shown Little Theater, Monday, Mar. 4, Tuesday, Mar. MODELLING- MOPP~STAGE ]I:S obesity to be a significant independent pre­ 5, 9 a m.-4 p.m. continuous: ACRF, Rm. Sb.-tcenth,AnnuaL-Bunny•Benefit:, dictor of cardiovascular (heart) disease. and 6C306, Wednesday, Mar. 6, Thursday, Mar. 7, rprescnfli; a risk factor or associated with a number of 9 a.m.-4 p.m., continuous, 5:30-9:30 p.m.: ------THE----- other diseases including diabetes, hyperten­ Westwood Bldg., Rm. 28, Monday, Mar. 11, 9 "CottbnTaiLCtr'CUS" sion, complications of pregnancy, osteo­ a.m.-4 p.m. continuous: Federal Bldg., 5C01, .-witlr,SpecialGu.,,;t, arthritis. and some cancers and infections. Wednesday, Mar. 13, 9 a.m.-4 p.m. continu­ "'T-BEAR.; A workshop on body weight. health and ous: Blair Bldg .. Rm. 110, Friday, Mar. 15, 9 longevity sponsored by the NIH Nutrition a.m.: Bldg. 13, Rm. G901: Tuesday, Mar. 19, Coordinating Committee and the Centers for 9 a.m.-4 p.m. continuous: Landow Bldg., Rm. Disease Control in 1982, concluded that in 7801, Thursday, Mar. 31 , 9 a.m.: Bldg. 31. the U.S. persons with below average weights Rm. 82B57, Monday, Mar. 25, 2:30 pm.; tend to live longer, if such weights are not a Bldg. 38A, Rm. B1N14A, Wednesday, Mar. result of illness or a history of significant med­ 27, 2:30 p.m. ical impairment. Special Prizes Overweight persons tend to die sooner than tickets- $ 2.50 average-weight persons, particularly those Special prizes will be awarded by R&W and who are overweight at younger ages. GSI Cafeteria Service to winners of the "Nutri­ TO BENEFIT PEDIATRIC ONCOLOGY The following activities to address the tional Pursuit" quiz (distributed desk-to-desk PROCEED$ OONAT£0TO'l.lDSAT IBE N.C.I." "Ways and Whys of Weight Control" during to NIH employees) at the sites of the "Fit or 'NATIOWAI. CANCER. IN~TITUTE'·PED!ATRIC 'llRANClf' National Nutrition Month are sponsored by the Fat Test." At each of these locations, besides FORTICKErS ~ MORE INFORMATION, NIH-NCC and its Subcommittee on Nutrition films and videotapes, information will be pro­ ~79-0083·€J:279·0307 ~ MAR.II Education, the Occupational Medical Service. vided on a special 12-week weight loss pro­ the Recreation and Welfare Association, NIH gram available to NIH employees through ling Moppetts & Stage ti's Sixteenth Annual Fitness Center and GSI Cafeteria Service. OMS. Bunny Benefit. presenting the "Cotton-Tail­ This special program offers sound nutri­ Circus" with special guest "T-Bear" on Satur­ 3-Part Videotape tional advice to help you lose weight safely day, Mar. 16, at 7 p.m., and Sunday, Mar. 17, OMS will present a 30-minute videotape en­ without special gimmicks, supplements or at 2:30 p.m., in Masur Auditorium, Bldg. 10, titled "The Fit or Fat Test" and a three-part foods under the supervision of OMS health Clinical Center. 45-minute slide/tape program on "Dangerous professionals. Tickets cost $2.50. All proceeds will be do­ Dieting" at the following locations and times: The GSI Cafeteria Service also plans to nated to "Kids at the NCI" Pediatric Oncology "The Fit or Fat Test": ACRF Amphitheater, help dieters stick to their weight-loss program Branch. Monday, Mar. 11, 11 :30 a.m. and 12:15 p.m. •: by offering "lean lunch and breakfast bunch" For tickets and more information call Poolesville T-8, Tuesday, Mar. 12, 2 p.m.; specials that will specify calorie count. Calo- 279-0083 or 279-0307 by Mar. 11. 0

Page 4 The NIH Record February 26, 1985 Obesity Is a Disease That Can Kill, Conferees Conclude Senior Wins Logo Contest At Plateletpheresis Center "Obesity ,s a killer It is a killer as smoking ideal measure of obesity because a person's is," says Dr. Jules Hirsch, a professor and age and percentage of body fat are not taken Launching a new recruiting campaign for senior physician at Rockefeller University and into account. volunteer donors, the NIH Plateletpheresis the panel chairman of the recent NIH consen­ However, the panel recommended that Center recently sponsored a "Design Our sus development conference on the Health physicians also use the body mass index Logo" contest at the Montgomery County Implications of Obesity. (BMI) formula as an additional test for obes­ Public Schools Visual Arts Center. Based on the scientific evidence that was ity. To determine the presence of obesity The wInnIng logo was designed by Cari presented at the conference by medical ex­ using the BMI formula. the weight of a person McBroom, a senior at Albert Einstein High perts in the field of obesity, a 14-member in kilograms is divided by the square of the consensus panel concluded that people who height in meters. According to the panel. a are 20 percent or more over their desirable person whose BMI is above 26 suffers from weight should be considered obese. Approxi­ "medically significant obesity." mately 34 million Americans fall into this cate­ Results of studies conducted both in the gory, and for these people, Dr. Hirsch said, United States and in Sweden have shown that "Treatment Is strongly advised." the Jocat,on of body fat may be iust as impor­ Millions of Americans are constantly tant as the amount of fat in determining the waging a battle of the bulge to shed excess health risks associated with obesity. weight so they can look and feel better about Although scientists do not yet fully under­ themselves. Although a better cosmetic ap­ stand the mechanisms involved, it has be­ pearance 1s the driving force for many people come clear that fat cells located in the upper to lose those extra pounds, there is over­ body- especially in the abdominal area­ whelming evidence that obesity has adverse exhibit greater adverse metabolic activity and effects on one's health and longevity, the con­ may pose a more serious threat to health than ferees concluded. fat cells found in the thighs, hips, and but­ "We want the American people to know that tocks. Thus, the panel members agreed that a obesity is an illness. It is not a state like lone­ person with a "pot belly" may be in more seri­ someness. It is a disease," Dr. Hirsch said. ous danger for developing complications School In Kensington. Miss McBroom is the Obesity, which 1s defined as an excessive from obesity than someone with a wide daughter of Dr. Cheryl Reichert, a pathologist storage of energy in the form of fat, has been bottom. in the Clirncal Center. c learly associated with diseases such as type The panel recommended that new tables Her effort, entitled "Platelets-the Link to II (maturity onset) diabetes, hypertension be developed that not only take into account Life"-earned her a $75 U.S. Savings Bond, (high blood pressure), hyperchotesterotemia a person's height and weight, but also fat cell which was presented by Gail Carter, director (high cholesterol blood levels), certain can­ distribution. which can be described by the of the Plateletpheresis Center. cers, and certain other medical problems. ratio of a person's girth at the waist to that at Susan Chamberlain. a senior at Northwood The panel also pointed out that many peo­ the hips. High School, received honorable mention and ple who are as little as 5 to 1O pounds over Speaking on behalf of the consensus panel, a $25 gill certificate their desirable weight may also be at an in­ Dr. Hirsch said future research in obesity The NIH Plateletpheresis Center, located in creased health risk. should include the search in infants and chil­ trailers adjacent to the CC Blood Bank. began As a guide for determining desirable dren for biologic markers that might serve as its second decade of service in April 1984. weights, the panel suggested that the 1959 predictors of adult obesity. Because less Is Functioning under the auspices of the Depart­ Metropolitan Life Insurance weight tables, known about the health risks of obesity in chil­ ment of Transfusion Medicine, the center 1s and in some cases the 1983 charts, are useful dren, Dr. Hirsch said that overzealous or mis­ charged with providing all the platelets for establishing obesity and determining ap­ placed treatment of childhood obesity could needed for transfusion at the CC. proximate health risks. possibly do more harm than good.-Bill With the assistance of modern. efficient The panel noted that neither table is an Ha ll □ cell-separating machines and the current recruitment campaign, the center is opt1m1stic about meeting its goals for 1985. "NIH employees are essential to the STEP Forum Will Present Video Teleconferencing platelet-donor program because of their prox­ imity to the Clinical Center and their willing­ The STEP Forum Series will present "Video cations of research. grantsmanship, changes in ness to donate, especially in case of emer­ Teleconferencing-ls the Technology Ready PHS policies, requests for proposals, contracts. gency," said Ms. Carter. "However, the need for NIH?" on Tuesday. Mar. 5. from 1 :30 to 4 etc. for platelets far exceeds the present p.m. in Wilson Hall., Bldg. 1. The guest will be Workshops and conferences could be pre­ employee-donor population." Polly Rash, vice president of SatServ. Serv­ sented at a single site-for example- Be­ Approximately 50 volunteer apheresis do­ ices by Satellite, Inc. thesda and distributed by satellite to the entire nors are required to meet the present de· The forum will include displays, demonstra­ United States reaching medical schools, uni­ mand of 500 units of platelets each week. tions, discussions. and dialogues on the capa­ versities, hospitals, and other locations includ­ Therefore the Plateletpheresis Center must bilities. utilities and costs of video teleconfer­ ing businesses and public access studios if rely upon the willingness of members of sur­ encing in relation to the NIH needs. needed. rounding communities to help fill this need Possible applications of video telecon­ Recruiters are hard at work cultivating ex­ ferencing include the face-to-face interactions Case Studies isting ties between the center and the com­ associated with the peer review process- site In addition to specific NIH possibilities. Ms. munity In and around NIH. They are also try­ visits, study section meetings, and national ad­ Rash will present video case studies on medi­ ing to establish new relationships In search of visory councils. cal trairnng and research, as well as those in­ new donors. volving other government agencies already In order to continue meeting the growing Many Uses using this technology. She will present a suita­ need for platelets, the CC must retain its cur­ Other NIH-related activities that could be ac­ ble mix of history, work with a provocative bal­ rent donors and expand the donor file by at complished through video teleconferencing in­ ance of success and horror stories. least 25 percent. clude providing mforrnation about programs STEP forums are open to all NIH professional Those between the ages ol 18 and 65 who and issues such as small businesses, minori­ and support staff. For more information call are in good health may donate platelets to ties, academic research enhancement. AIDS, Arlene Bowles, STEP Program Office, Bldg. 31, help save lives. Anyone interested 1n becom­ animal welfare, human subjects, scientific eth­ Rm. 1663, 496-1493. 0 ing a donor may call 496-4321 for more ics, national research resources, medical appli- information. D

February 26, 1985 The NIH Record Page 5 Prostate Cancer Common Among U.S. Men; Seminar on Magnetic Imaging Incidence of Disorder Increases With Age Scheduled for February 28

Prostate cancer is one of the most common use tobacco, alcohol, coffee, or tea, but Magnetic resonance imaging (MRI)- for­ cancers among United States men. Mainly a whose fa t consumption is similar to that of merly known as nuclear magnetic reso­ disease of men over age 65, its incidence in­ other white males in the United States, have nance-will be the subject of the next NIH creases with age. about the same risk of prostate cancer as Science Writers Seminar. It will be held on The prostate gland, located at the base of other white men. Prostate cancer is the most Thursday, Feb. 28. from 9 a m. to 12·30 p .m the penis surrounding the urethra. produces common type of cancer among Mormons. In the ACRF Amphitheater, Bldg 10 seminal fluid. The two most common condi­ Prostate growth and function depend on NIH intramural scientists will describe how tions that affect it are enlargement and can­ the hormone testosterone, formed in the testi­ MRI works and how they are using ii to study cer, but the two do not seem to be related to c les. It is possible that d iet aflects the pro­ various diseases. each other. duction of sex hormones, and that this in Dr. Richard Knop. stall physician and Black men in the United States have the turn, may affect the risk of prostate cancer. radiologist. Diagnostic Radiology Depart­ highest rate of prostate cancer in the world. Prostate cancer as well as cancers of the ment, Clinical Center. will be the moderator. Between 1975 and 1977, the rate among colon, rectum, and female breast may be as­ An introduction and overview of MRI will be black men in Atlanta was about 133 per sociated with dietary fat intake. Prostate can­ presented by Dr. David I. Hoult, physical sci 100,000, compared with 74 per 100.000 for cer has been linked with the consumption of ent1st. Biomedical Engineering and Instru­ white men in the same city. animal fat and protein among several ethnic mentation Branch, Div1s1on of Research The high incidence of prostate cancer groups in Hawaii. Services. among blacks has occurred only In the last Workplace exposures to cadmium during Dr. Giovanni Di Chiro. chief Neuro­ few decades, suggesting that social rather welding, electroplating , and the production of radiology and Computed Tomography Sec­ than genetic factors are responsible. alkaline batteries may increase the risk of tion, Surgical Neurology Branch, National In Prostate cancer is also common in north­ prostate cancer But dietary exposures to stItute of Neurological and Commun1cattve western Europe. Incidence is lower in the cadmium- from oysters for example- do not Disorders and Stroke, will describe the cur­ Near East and in parts of Africa and South seem to increase nsk rent status ol MRI in evaluating the central America. The lowest rate of prostate cancer is Workers in the rubber industry may also be nervous system. found in Japan. at increased risk. The use of MRI to study cardiac hyper­ Studies of migrating populations have sug­ None of these studies is conclusive, trophy- one of the leading causes of sudden gested that environmental factors such as however. death-will be discussed by Dr. Barry J. diet and lifestyle play an important role In the Thus. the causes of prostate cancer are Maron. senior Invest1gator, Cardiology nsk of developing prostate cancer For exam­ unclear. Although there are no known meth­ Branch, National Heart, Lung, and Blood ple, prostate cancer and fat intake are higher ods of prevention, the link between diet and Institute among Japanese in Hawaii than in Japan. cancer and the role of workplace carcinogens Dr Andrew J Dwyer, staff radiologist, Di­ Mormons who, for religious reasons, do not are now being stud1ed.-NCI Report D agnostic Radiology Department. CC will ex­ plain how MRI is being used in cancer detection. Dr Victor J. Sank. MRI phys1c1st. Diagnos­ tic Radiology Department, CC, will comment on luture applications of MRI Following the seminar, there will be a dem­ onstration of the CC's MRI scanner. Science Writers Seminars. sponsored by the intramural scientists of NIH and the Divi­ sion of Public lnlormat1on, OD, are designed to provide members of the press with back­ ground information on various areas of re­ search conducted at NIH. For additional information. call Bobbi Bennett, 496-1766. □

The first Wallace P. Rowe Award for Excellence in Virologic Research was presented to Dr. Rex Risser, FIC Director Dr. Craig K. Wallace and Nancy (second from I.) of the McArdle Laboratory for Cancer Research, Madison, Wis. Dr. Janet Hartley, (I.) Wallace hosted a reception at the Stone House head of the Viral Oncology Section, Laboratory of Viral Diseases, announced the award at the on Jan. 16 for 67 newly arrived visiting fellows first annual Wallace P. Rowe Symposium on Animal Virology, held at Lister Hill Auditorium Feb. 11 and and their spouses. Also In attendance were Ors. 12. Dr. Risser was cited for his contributions to the "understanding of the biology and genetic control of Wyngaarden, Rall, Chen, and Wyatt and various Abelson virus lymphomagenesis and to the concept of murine leukemia viruses as endogenous Fogarty Scholars-in-Residence. The reception elements." The symposium was convened to honor the late Dr. Rowe, a renowned NIAID virologist. provided an opportunity for the new arrivals to Others shown are: Dr. Malcom Martin (second from r.), chief, Laboratory of Molecular Microbiology, get to know one another as well as the senior and Dr. Robert Chanock (r.), chief, Laboratory of Infectious Diseases. staff.

Page 6 The NIH Record February 26, 1985 Research Physiologist in VRB VISITING SCIENTISTS Wins in Student Competition 12/18 Dr. Anthony Kai-Cho Ho, Hong Kong. Spon­ 116 Dr. Bernard D. Duly, France Sponsor Dr Patricia M Schmidt. research phys1olog1st In sor· Or. David Klein, Laboratory of Developmental Jeffrey Barker. Laboratory of Neurophysiology, the Veterinary Resources Branch. DRS, won Neurobiology, NICHO, Bg. 6, Rm. 1A15. NINCOS. Bg 36. Rm 2C02 the g raduate student research competition at 12118 Dr. Gregory Harper, Australia. Sponsor: 116 Dr. Max R. Dursteler, Sw11zerland Sponsor Dr the 1985 International Embryo Transfer Society Or. William A. Gahl, Human Genetics Branch, Robert H Wurtz, Laboratory of Sensorimotor Re­ meeting held 1n Montreal. Canada on Jan. NICHO, Bg. 10, Rm. 8044. search. NEI. Bg. 10, Rm . 6C420 20-22. 12/19 Dr. Chaiyod Bunyagldj, Thailand. Spon­ 116 Dr. Masafumi Fujimoto, Japan Sponsor· Dr Ms. Schmidt Is in charge of the Embryo sor: Or. John Mclachlan, Laboratory of Repro­ Erm11110 Cosla. Laboratory of Preclrn;cal Pharmacol­ ductive and Developmental Toxicology, NIEHS, ogy, NIMH. W1,11am A Wht ie Bldg , St El1zabcths Cryopreservation Program of VRB's Small Ani­ Research Triangle Park, N.C. Hospital mal Section She 1s also a doctoral candidate 1n 12121 Dr. Fumitake Ogushl, Japan. Sponsor: Or. 116 Or. Angelika Hahn, West Germany Sponsor a collaborative reproductive physiology pro­ Ronald Crystal, Pulmonary Branch, NHLBI, Bg. Dr Henry D Webster. Laboratory of Exper,mental gram Involv1ng the National Zoological Park. 10, Rm. 6006. Neuropathology, NINCDS. Bg 36, Rm 4817 Sm1thson1an lnst1tut1on, and the department of 12/23 Dr. WIiiiam J. Dinning, Australia. Sponsor: 1 •6 Or. Elinar Stefansson, Iceland Sponsor Or physiology al the Unilormed Services Univer­ Dr Robert Nussenblatt, Clinical Branch. NEI, Bg. Robert Nussenblatt. Clinical Branch, NE. Bg 10 sity of the Health Sciences 10, Rm. 1ON202 . Rm 10019 12/23 Dr. Avi Eisenthal, Israel. Sponsor: Dr. Ste­ 1,7 Dr. Ayo Abe, Japan Sponsor Dr Richard J Rodent Embryos ven A Rosenberg. Surgery Branch, NCI, Bg. 10, Hodes Immunology Branch NCI. Bg. 10 Rm Rm. 2B44. 4B10. The VRB Embryo Cryopreservallon Program 12/23 Dr. Wang Ning, China Sponsor: Or. An­ 117 Dr. Claudio Dali, llaly Sponsor Dr. Barbara K. freezes and stores laboratory rodent embryos drew Bryd, Division of Biochemistry and B1ophys­ Vonderhaar. Laboratory ol Pathophys1ology, NCI from the NIH genetic resource to help ensure Ics, NCOB, Bg . 20, Rm. 514. Bg 10 Rm 5B56 the survival and genetic punty of valuable 12•2/4 Dr. Mitsuhide Noshior, Japan Sponsor Dr 1,7 Dr. Fabian Gusovsky, Argentina Sponsor Dr strains Masahiko Neq1sh1 Laboratory of Pharmacology John Daly Laboratory of B10organic Chemistry During 1984 VRB banked 10.000 frozen em­ NIEHS, Research Triangle Park. NC NIADDK, Bg /4 Rm 212 bryos-1,000 from each of 1O selected rodent 01/01 Dr. Narayan Bhat, India. Sponsor: Or. 1- 7 Or. Genevieve lnchauspe, France Sponsor· strains As embryo cryopreservation tech­ Richard Ascione, Laboratory of Molecular Oncol­ Or Frank DeFilltppes Laboratory of V1rnl Diseases. niques improve. the numbers of embryos re­ ogy, NCI, FCRF, Bg 469, Rm. 102. NIAID Bg 5, Rm. 333 0 1/01 Dr. Elizabeth Bone, UK. Sponsor Dr. 1,9 Dr. Francoise Forquignon, Hance. Sponsor quired will decrease The genetic resource 1n Leonard Kohn, Laboratory of Biochemical Phar­ Dr Igor B Daw10, Laboratory ol Molecul,H Genet­ VRB conta ns more than 250 rodent and rabbit macology, NIAODK, Bg. 4, Rm. 81-31 ics, NICHO. Bg 6. Rm 408 vanet1es Most of the frozen embryos will be Ot.-01 Dr. Keith Brocklehurst, UK Sponsor 1·9 Dr. Essam Karawya, Egypt Sponsor Dr Rob used lor re-deriving particular strains at appro­ Or. Harvey Pollard, Laboratory of Cell Biology ert Maritn Laboratory of Molecular Biology, priate times. but some will be used for embryo and Genetics, NIAODK, Bg. 4, Rm. 312. NIADDK Bg 2, Rm 310 longevity studies 01/01 Dr. Diana Callender, Jamaica. Sponsor: 1 9 Dr. Yasuo Kubota, Japan Sponsor· Dr Embryos to be preserved in this way are Dr. Dan Longo, Medicine Branch, NCI, Bg. 10, Thomas J Lawley Dermatology Branch NCI. Bg bathed in a cryoprotectant fluid to prevent ice Rm 12N236. 10, Rm 12N252. crystals, frozen slowly (0.5°C per minute) to a 01/01 Dr. Kyouhoon Han, Korea. Sponsor: Dr. 111 O Dr. David Findlay, Australia. Sponsor Or Chien-Hua Niu, Laboratory ol Experimental Marian Young. Mineralized Tissue Research predetermined temperature. and then plunged Carcinogenesis, NCI, Bg. 37, Rm. 3B27. Branch, NIDR, Bg 30 Rm 406 into liquid nitrogen for long-term storage at 01101 Dr. Michael Hubbard, New Zealand. Spon­ 1 10 Dr. Peter Gierschik, Germany Sponsor Dr -196°C sor: Or. Claude Klee, Laboratory of Biochemistry, Allen Spiegel. Metabolic Diseases Branch, Ms Schmidt's award-winning poster-oral NCI, Bg. 37, Rm. 4C06. NIADDK. Bg 10. Rm. 9C101 presentation was titled "Variables Influencing 01/01 Dr. Juan-Carlos Lacal, Spain. Sponsor: 1. 10 Dr. Yuji Karasaki, Japan Sponsor Dr Post-thaw Embryo Survival Rates 1n Mice " She Or. Stuart Aaronson, Medicine Branch, NCI, Bg. Kathryn Zoon. National Center for Drugs and Bio­ compared various kinds of techniques and 10, Rm. 1E24. logics. Bg. 29. Rm 518 01/01 Dr. Fathla Marni, France. Sponsor: Or. 1110 Dr. Lucia Pirisi, Italy Sponsor Dr Joseph Thomas Kindt, Laboratory of lmmunogenet1cs, 0 1Paolo. Laboratory ol Biology, NCI Bg. 37. Rrn NIAID, Bg. 5, Rm . 8104. 2A19 01/01 Dr. Hidetaka Masuda, Japan. Sponsor: Or. 1/11 Dr. Huixin Jiang, China Sponsor: Or Jay Robert Ozols, Medicine Branch, NCI, Bg . 10, Rm. Robbins, Dermatology Branch NCI Bg 10, Rm. 13N260. 12N258 01/01 Dr. Hiroshi Nonoguchi, Japan. Sponsor: 1114 Dr. Karl Belanger, Canada Sponsor. D1. Jerry Or. John Pisano, Laboratory of Chemistry. NHLBI, Collins. Clinical Pharmacology Branch NCI. Bg. 10 Bg, 10, Rm. 7N262. Rm. 6N119. 01/01 Dr. Zhao Li-Kan, China. Sponsor: Or. Clar­ 1/14 Dr. David Parry, United Kingdom Sponsor: ence Gibbs, Laboratory of Central Nervous Sys­ Or Alasdair Steven. Laboratory of Physical Biology, tems Studies, NINCOS, Bg. 36, Rm. 4A17. NIADDK. Bg. 6. Rm. 114 1/ I Dr. Wlestaw Buchowlecki, Poland Sponsor· 1/14 Dr. Thyagarajan Srikantha, India Sponsor: Dr Jose! P,tha. Laboratmy ol Cellular and Molecu­ Dr Michael Bustin, Laboratory of Molecular Car­ lar Biology, NIA. GRC. cinogenesis. NCI. Bg 37, Rm 3D20 01/02 Dr. Michael Marks, U.S. Sponsor: Or. 1114 Dr. M. B. Vasudevachri, Indra Sponsor Or Henry Metzger. Arthritis and Rheumatism Branch. Norman Salzman. Laboratory of Biology of Viruses. NIADDK. Bg. 10, Rm. 9N240. NIAIO, Bg 5. Rm 326 113 Dr. Donald T. Drinkwater, Canada. Sponsor. 1/14 Dr. Geoffrey Sunahara, Canada Sponsor· Dr. Dr Reubrn Andres, Clinical Physiology Branch, George W Lucier. Biometry and Risk Assessment NIA. GRC Program. NIEHS. Research Triangle Park, N.C. 01/04 Dr. Jon Askaa, Denmark. Sponsor: Dr. 1115 Dr. Valerie Anne Lucas, United Kingdom Albert Kap1Kian, Laboratory of Infectious Dis­ Sponsor· Dr Samuel Zigler, Laboratory of V1s1on eases, NIAID, Bg. 7. Rm. 103. Research. NEI, Bg 6. Rm. 235. 114 Dr. Mario Maggi, Italy. Sponsor: Dr. Andreas 1116 Or. Koiti lnokuchi, Japan Sponsor Or Arthur Chrambach. Laboratory of Theorellcal and Phys1ca W. N1enhu1s. Clinical Hematology Branch, NHLBI Biology, NICHD, Bg. 10, Rm 12N212. Bg 10 Rm. 7C103. Patricia Schmidt, VRB Embryo Cryopreservation Program, regularly evaluates new preservation techniques tor valuable rodent strains. Fish and visitors smell in three days.- 8enjamin Experience constantly proves that every man who Franklin has power is impelled to abuse 1t.-Montesquieu equipment to identity those producing the best All the troubles of man come from his not knowing Experience is the name everyone gives to their results with embryos from three NIH mouse how to sit still.-Blaise Pascal mistakes.-Oscar Wilde strains. n

February 26, 1985 The NIH Record Page 7 Three New Dental Centers Funded by NIDA Dr. Robert L. Berger Elected To Study Causes of Crown and Root Decay Fellow of Physical Society The National Institute of Dental Research ology and chairman of dental research at the Or Robert L. Berger, chief of the Section of recently established three new research University of Rochester Medical Center, will Biophysical Instrumentation, Laboratory ol centers-the first of their kind in the U.S.-to oversee the Rochester Cariology Center, a Technical Development, National Heart, Lung, study dental caries, decay that attacks the collaborative effort between the University of and Blood Institute, has been elected a fellow crowns and exposed roots of teeth. Over the Rochester Medical Center and Eastman Den­ of the American Physical Society. next 5 years, approximately $6.2 million w ill tal Center. Besides studying root surface car­ The citation reads "For pioneering and sus­ be allocated to the centers, enabling scien­ ies, the Rochester Center will concentrate on tained contributions In the application and anal­ tists to increase knowledge about the causes the early 1dentif1cat1on of caries-prone 1nd1- ysis of physical measurements In the research and prevention of caries. v1duals of all ages so that preventive meth­ in molecular biophysics." Located at the University of Iowa, the Uni­ ods and treatment can be started. Dr. Berger received his Ph.D in physics from versity of Rochester, and Forsyth Dental Cen­ Other studies will locus on combating the Pennsylvania State University He then ter in Boston, the centers will integrate find­ harmful oral bacteria: the formation of spent 2 years at Cambridge University as a ings from basic and clinical research and plaque: increasing host resistance to decay­ British-American exchange fellow ol the Ameri­ promote the use of preventive methods to promoting agents: preventing caries through can Cancer Society He J0ined the physics de­ benefit the public. diet modification: and treating cancer pa­ partment at Utah State University where he Although tooth decay among c hildren in tients receiving head and neck radiation ther­ rose to the rank of associate professor He the United States is declining, the average apy to avoid rampant caries. The Rochester came lo NIH In 1962. American child still has 11 cavities by age Center will receive $2 million over a 5-year During his years at NIH, he has developed a 17 period. variety of stopped and quench flow apparatus, In addition, a new caries problem is The caries research center at Forsyth will the latter presently berng used In over 14 labo­ emerging in a different segment of the popu­ be directed by Dr. Paul F. DePaola, who has ratories worldwide for sarcoplasmic reticulum lation. The expanding number of elderly in been active 1n clinical testing and epidemio­ and ATPase k1 net1c research this country-and the g rowing proportion of logical studies for 20 years. Populations at He developed the "Berger Ball Mixer" which elderly who retain their own teeth-is making especially high or low risk for developing 1s widely used 1n flow apparatus The great im­ root surface caries an increasingly important caries-including diabetics, chronic users of provement 1n thermistors which he initiated with problem. Old age 1s often accompanied by antibiotics. consumers of refined sugar at re­ a commercial firm led to the development of shrinking gums, a process that exposes root stricted levels. and 1ndiv1duals receiving vari­ the thermodllut1on catheter. surfaces. The resulting decay of these sur­ ous levels of fluoride-will be studied. The From this collaborat1on also came an abso­ faces is particularly painful and difficult to center will receive $2.4 m1ll1on over the next 5 lute temperature standard for use In b1ochem1- treat. years to conduct clinical and basic studies of cal and clinical chemistry laboratories and a Too. bacteria which cause root decay ap­ root caries. new fast thermistor detector useful In his re­ pear to be different from those associated Basic studies will focus on the microbial or- search on fast enzyme reactions 1n which the with caries in the crowns of teeth. 1g In of root surface caries. biochemical and heat of the reaction can be observed Dr. Brian Clarkson, who has been head of m1crob1olog1cal aspects of root surface car­ In the early 1970s. Dr. Berger initiated the the division of cariology, department of ies: immunological aspects; physical­ use of microprocessors for instrument control pedodontics at the University of Iowa Dental chemical and m1c rob1olog1cal aspects of root As an ad1unct to the d1g1tal computer he School since 1976, will direct the Specialized caries formation. 1nteract1ons between root developed- with Prof. Norman Davids at Penn Caries Research Center at the College of surface plaque and fluoride. and the struc­ State- the finite element simulation technique Dentistry, University of Iowa. This center will tural characterization of root canes m natu­ tor the analysis of complex heat conduction or receive $1.8 million over the next 5 years to rally occurring lesions, experimental animal d1flus1on problems in which simultaneous study the prevention of caries, including the models, and 1n vitro (laboratory) systems. chemical reactions occur influence of microbial products on the solu­ "The goal of the new centers 1s to broaden The method has been applied to many areas bility of tooth surfaces: the acidity of plaque and strengthen the scientific base underlying of science particularly where econom1zIng of that has accumulated between teeth; simple caries research by developing cornpul1ng lime 1s needed and the complexity and complex carbohydrates as possible interdisciplinary research efforts to attack the of the problem Is beyond the scope of classical causative factors in root caries: caries problem," explains NIDA Director Dr. mathematical methods. The method has been immunological investigations of root surface Harald Loe. "We anticipate that this focused extensively used to model pulsatIle bifurcated caries: synthesis and testing of potential combination of basic and clinical research flow In the aorta antiplaque agents; and bacterial relation­ will achieve very useful and practical health Recently, Dr. Berger has developed a series ships In an animal model. benefits that will further help reduce or elimi­ of calorimeters for studying a wide variety of b1- Dr. William H. Bowen, professor of microb1- nate tooth decay ." □ ochem1cal reactions both 1n whole cells and In solution He 1s the aulhor of over 90 papers and 1s CHAMPUS Mailing Address chairman and originator of the b1ophysIcal discussions of the Biophysical Society. 0 Changed for Officers

Effective Feb. 1, CHAMPUS claims in the CHAMPUS. Retired members are also el1g1ble Mid-Atlantic Region and the District of Colum­ for CHAMPUS However, active duty mem­ bia will be processed by the Wisconsin Phys1- bers are not elIg1ble. c1ans Service. Claims should be senl to the CHAMPUS questions st1ould be directed to appropriate address below based on the the health benefits advisor at the nearest uni­ state in which the care was received lormed services medical fac1\\ty or the NIH comm1ssIoned officer staff (496-42 t 2) ..J CHAMPUS;CHAMPVA. W1scons1n Physicians Service. PO Box 8960 (Del.), 8961 (DC ), Four employees of the Data Editing and Re­ (Md) search Unit, Supply Operations Branch, received 8962 8963 (NC). 8964 (Pa): 8966 (Va) Madison WI 53708 Words are the most powerful drug used by an award for special achievement. (L to r): Sari mankind- Rudyard Krplmg Tenn, Pat Sealfon, Mae Bate and Tanja Maseley. The toll lree number for all five states and Presenting the awards are James V. Marx, chief, D. C. IS 1-800-356-5954 Cataloging Requirements and Data Editing Sec­ tion, and Robert M. Masucci, Sr., chief, Supply Only the dependents of active duty/retired. The golden rule 1s that them who has the gold Operations Branch. or deceased members are el1g1ble for rule.-The Wizard of Id.

Page 8 The NIH Record February 26, 1985 CC Scientists Test Out Immune Suppression Therapy TRAVELER'S D Which Might Reverse Heart Muscle Deterioration (Continued from Page 1)

An 1mmunosuppressive treatment that may cramps, nausea, malaise, and, less com­ TECHNIQUE OF TRANSVENOUS reverse heart muscle damage In patients suf­ ENDO MYOCARDIAL BIOPSY monly, fever or vomiting. II usually begins fering from progressive deterioration of the suddenly, lasts for several days, and is self­ heart muscle's ability to pump blood is now hm1ting Approximately 2 percent of cases being tested by scientists in the Clinical Cen­ may persist for longer than 1 month. ter Critical Care Medicine Department. Data from a study of over 18.000 Swiss Ors. Joseph E. Parrillo, chief of the CC's travelers suggest that the highest areas of Cntical Care Medicine Department, Anthony risk for travelers' diarrhea are developing S. Fauci of the National Institute of Allergy countries in Latin America. Africa. the Middle and Infectious Diseases, Douglas Rosing of East and Asia. Inhabitants of these areas are the National Heart, Lung, and Blood Institute at risk of diarrheal diseases as well Diarrhea and colleagues are focusing on idiopathic di­ Is a maior cause of infant mortality in many of lated cardiomyopathy-its cause and re­ these countries. sponse to the anti-inflammatory agents­ The most common causative agents of trav­ prednisone and cyclophosphamide. elers' diarrhea are bacterial, primanly enterotoxIgenic Escherichia coli. Congestive cardiomyopathy, a disease Biopsy ____, , The 14-member consensus panel, chaired marked by progressive deterioration of the Forceps heart muscle, strikes Americans of all ages. by Dr. Sherwood L. Gorbach, professor of The majority of its victims die within 4 years med1c1ne and microbiology at Tufts University following the onset of cardiac dysfunction. School of Medicine, recommended prudent Symptoms of the disease include short­ dietary practices as preventive measures. Re­ ness of breath, fainting episodes, fatigue, flected in the well-known phrase, "boil It, cook swelling in the ankles. palpitations, heart en­ It, peel 1t, or forget 1t." these measures includEJ largement or occasionally pains in the chest. avrndance of raw vegetables, raw meal, raw Currently, there is no proven therapy that A diagram of the !ravenous endomyocardlal seafood. tap water and ice. unpasteurized biopys technique shows the IJF (internal jugu­ dairy products, and unpeeled fruits. reverses heart muscle damage although lar vein), the SVC (superior vena cava), the RA some medications will improve symptoms of (right atrium), the RV (right ventricle), and the Among beverages, bottled carbonated heart failure. LV (left ventricle). drinks, beer, wine, hot coffee or lea, and Dr. Parrillo and his collaborators hope to boiled or treated water convey the least risk determine if anti-inflammatory therapy is spond lo an anti-inflammatory treatment. The The panel conceded. however, that even with benefical and in which form of the disease 11 study indicates the importance of diagnosing attenllon to dietary practices. travelers' diar­ would be most helpfuL myocard1t1s and instituting an anti­ rhea may still occur. Recent studies conducted by Dr. Parrillo inflammatory therapy which may produce im­ The panel's recommendations for treatment suggest that inflammatory heart infec­ provement In some of these patients. More of travelers' diarrhea are· tion-myocard1tis-may be involved in the research Is needed to support this theory. • Take fluids such as fruit IuIces or disease process of a significant portion of lmmunosuppressive therapy with pred­ caffeine-free soft drinks and salted crackers patients with congestive dilated nisone and cyclophosphamide has been suc­ to maintain fluid and electrolyte balance Al­ cardiomyopathy. cessful in a wide variety of inflammatory dis­ cohol and dairy products should be avoided. By using a state-of-the-art catherizat1on eases. Although considered effective • For rapid relief of symptoms. antimotility technique that samples pieces of weakened treatment for inflammatory diseases the drugs such as d1phenoxylate (Lomotil) or heart 1ssue-transvenous endomyocardial bi­ drugs have potentially harmful side effects. loperamide (lmodium) may be taken. opsy (TEB)-Dr. Parrillo conhrmed that 19 of Predn1sone can be associated with a high Alternatively, bismuth sal1cylate (Pepto 100 patients with suspected congestive rate of infections, especially in chronic users Bismol) may be used. cardiomyopathy had had myocard1fls. Used of this corticosteroid hormone. • Aller three or more loose stools with asso­ for more than 10 years the catheter technique The myocarditis study employs an ciated symptoms, a short course of has been used to obtain myocardium (heart alternate-day prednisone regimen to mini­ antimicrobial agents may be of benefit. These sac) samples In a wide variety of heart dis­ mize the risk of infection. Cyclophosphamide may be obtained In advance of travel to avoid ease. It is also used to predict rejection of can cause sterility in men and women of buying potentially dangerous over-the­ cardiac transplants. childbearing age. counter drugs abroad. Recommended The current study revealed inflammatory All patients entering the heart study are in­ ant1m1crob1al drugs are tnmethoprim/ cells in the biopsied heart tissues of a signifi­ formed of potential risks. However, by care­ sulfamethoxazole, tnmethopnm alone, or cant proportion of congestive cardio­ fully monitoring the patients receiving these doxycycline. myopathy patients. medications and by employing special • If diarrhea persists accompanied by sen­ What causes myocard1t1s Is not clear but dosing adjustments, NIH researchers are ous fluid loss, fever, and blood or mucus in often the patient suffers flu-like symptoms, fe ­ able to prevent most of the serious side ef­ the stools, the traveler should seek medical ver, elevated erythrocyte (red blood cell) fects of the medications. attention. sedimentation rate (a nonspecific marker of With 2 more years of investigation to go, The consensus panel also considered what inflammation) and leukocytosis (increase in Or. Parrillo and colleagues are at the fore­ research areas need to be explored to im­ white blood cells). Many patients suffer with front of cardiac research. The future looks prove currcnl methods of preventing and symptoms of heart failure and only myo­ promising for innovative treatments in the treating travelers· diarrhea. The panel cited cardial biopsy can determine if myocarditis is field of heart disease.-Mlckey Hanlon the need for expanded ep1dem1ological stud­ the underlying cause. ies, monitoring of drug-resistant pathogens in Some data suggest a small percentage of Real Estate Seminar Planned developing countries, development of rapid these patients had viral infections prior to d1agnost1c techniques, new approaches to contracting the disease. Another therapy Merrill Lynch Realty will present a real es­ vaccine development for travelers' diarrhea, suggests that individual's own immune sys­ tate seminar on Monday, Mar. 4, from noon to and large-scale drug surveillance studies. tem may produce an inappropriate inflamma­ 1 p.m in Conf. Rm. 4, Bldg 31 The panel concluded with lhe recommen­ tory response, damaging the heart muscle. A Ingrid Blitz of Golddome Mortgage Com­ dation that physicians discuss with their pa­ combined theory states that an initial viral in­ pany will discuss adjustable and fixed rate tients the potential risks of taking fection damages the heart muscle and pre­ mortgages, as well as refinancing, second antimicrobial drugs and inform patients cipitates an abnormal immune response. trusts and creative techniques and how this planning travel of the availability of effective Recent evidence has shown that a small affects your purchasing power both as a treatment, which can provide prompt relief in group of patients with myocarditis may re- buyer and a seller . □ most cases. □

February 26, 1985 The NIH Record Page 9 Dr. Blot Appointed Chief, Willard Lee, NIDR's First Black Professional, Biostatistics Branch, NCI Retires After 37 years of Federal Service

Dr. William J. Blot has recently been ap­ Willard Lee, a chemist with the National In­ pointed chief, NCI Biostatistics Branch The stitute of Dental Research and the first black branch develops and uses statistical methods professional hired by the Institute, retired to identify and describe the environmental and Jan. 4, having served 37 years in Federal host determinants of cancer. service. Dr. Blot has over 120 publications in cancer At his retirement, he worked in the Labora­ epidemiology and biostatistics and has been tory of Developmental Biology and primarily interested in evaluating environmental Anomalies. and lifestyle factors in areas with a high rate o! A graduate of Virginia Union University in a particular cancer. Richmond in 1951 , Mr. Lee later did graduate work at Howard and Georgetown Universities. His first assignment atter joining the NIDR staff in 1955 was to conduct fluoride analysis studies. By analyzing water, bone and soft tissue specimens brought in from all parts of the country, he was able to provide the neces­ sary data needed to help establish the safety of fluoride for use as a preventive agent in combating dental caries. At that time, Mr. Lee conducted his re­ (L tor): Dr. Thomas Malone, Willard Lee, and Dr. search studies under the direction of noted Harald Loe look at photos of the NIH campus fluoridation pioneers Ors. McClure. Zipkin, taken in 1945 and 1957, wh ich were presented to and Armstrong. He also coauthored several Mr. Lee at his retirement party. articles published on the topic 1n professional dental journals. 1950s when segregation was still prevalent. A retirement party held Jan. 10 was at­ Dr. Harald Loe, NlDR Director, presented tended by many friends and relatives. Mr. Lee with a certificate of merit and thanked Dr. Thomas Malone. NIH Deputy Director, and him for his many years of service to NIDR, guest speaker, said, "Mr. Lee, you are an in­ NIH, and the biomedical research community stitution in your own right, a trail blazer for be­ at large. Dr. Blot coming the first black professional to be hired Now in retirement, Mr. Lee plans to become by the NIDR. and perhaps by the NIH." even more involved with his service fraternity Dr. Malone also pointed out that Mr. Lee activities. He also plans to spend as much Before coming to NCI in 1974 as a health had been active in the NIH and Montgomery time as possible with his 5-year-old grand­ stat1stic1an, he received a Ph.D. in statistics County efforts to hire blacks during the early daughter, Razi. D from Florida State University in 1970. He then spent 2 years in Hiroshima. Japan with the Atomic Bomb Casualty Commission, studying the long-range effects of radiation on popula­ Dr. Newburgh Joins Pharmacological Program tions exposed to the bomb. This was a joint ef­ fort between the Japanese Government and Dr. M. Janet Newburgh recently io1ned the In 1980, Dr. Newburgh came to NIH as a the U.S. National Academy of Sciences. National Institute of General Medical Sci­ grants associate. where one of her assign­ For the next 2 years, Dr. Blot was an assist­ ences as a program administrator in the Phar­ ments was with the Pharmacological Sci­ ant professor in the departments of interna­ rnacolog1cal Sciences (PS) Program ences Program at NIGMS. In 1981 , she be­ tional health and biostatistics at Johns Hopkins Dr Newburgh was born in Miami. Okla., came a program administrator in the University. Since 1978, he has been chief of the and received her B.A. in chemistry from Oculomotor Disorders and Strabismus Pro­ analytical studies section in the Environmental Oklahoma State University. She attended gram of the National Eye Institute, adminis­ Epidemiology Branch. graduate school at the University of Illinois, tering research grants in disorders of eye "We conduct research on statistical methods where she received M.S. and Ph.D. degrees movements, visual processing, and refractive !or a variety ol cancer studies. We also work in chemistry. error. with other groups to design and perform stud­ From 1968 to 1971, she was an honorary In her new position. she will administer re­ ies to calculate the incidence and mortality of professor in the department of chemistry at search grants on the molecular basis of drug cancer and evaluate nsk factors in certain pop­ the Universidad National Autonoma de action. She will also oversee research training ulation groups,"' 5ays Dr. Blot. Colombia in Bogota. During part of this time, grants in basic and clinical pharmacology "I "Some studies are done in collaboration with she was also an instructor in biochemistry at really am looking forward to the work 1n PS foreign countries. China, for example, offers ex­ the Coleg10 Nueva Granada in Bogota. because the science is so close to my own cellent opportunities for epidemiologic and sta­ Dr. Newburgh's interest in biochemistry led background," she said. tistical studies." he continues. "There are un­ her to become a research associate at Among the honors Dr. Newburgh has re­ usual distributions of cancer and high levels of Oregon State University in the department of ceived is the Parke-Davis fellowship for grad­ exposure to some environmental agents. The biochemistry and biophysics: she next uate research 1n chemistry. She was a na­ population 1s accessible and cooperative and worked as a research fellow in the d1vis1on of tional merit finalist in high school. She 1s a the large populations provide expanded data medical genetics at the University of Oregon member of the American Chemical Society, for analyses of cancer etiology. Health Sciences Center until 1973 the American Society of Biological Chemists. "In many of these studies, we compare the She then returned to Oregon State as an the American Association tor the Advance­ characteristics of people in a population both assistant professor m the department of b10- ment of Science. and the New York Academy with and without a particular cancer and note chem1stry and biophysics. She was an asso­ of Sciences □ the differences " He says, "We want to develop ciate professor by 1978, when she left more precise statistical melhods for these stud­ Oregon to take a position at the University of ies, so that each proiect will provide us v1ith a North Carolina. Chapel Hill. as an associate The handwriting on the wall may be a maximum amount of information." 0 professor in the department of chemistry. forgery.- Ralph Hodgson

Page 10 The NIH Record February 26, 1985 New Personal Computer User Center Opens; GALLO Group or One-On-One Instruction Available (Continued from Page 1) that it is international in scope as well as im­ pact. for we are honoring a scientist from the United States and three scientists from Ja­ pan, working independently and in collabora­ tion. sharing ideas and results, all aiming for a common goal and a common good." Joining Dr. Hammer for the presentation were the other members of the Hammer Prize Selection Committee: Dr. Ronald Levy of Stanford University; Dr. Vincent DeVita Jr., NCI Director: and Dr. Renato Dulbecco, dis­ tinguished research professor at the Salk In­ stitute and Nobel laureate in medicine for cancer research The $100,000 Hammer Prize will be awarded each year for the next 7 years to the scientist or scientists deemed to have made the greatest contribution toward a cure for cancer. The annual awards are part of a total Dr. Malone (second from r) receives the new center poster from the NIH User Resource Center. $2 million 1n contributions pledged in 1982 by Steering committee members (I to r): Tom Barbour, DPM, Dave Songco, DCRT, and Ken Thibodeau, OMP. the Hammer Prize Foundation. In addition lo the annual $100,000 Hammer Prize, Dr. Hammer has announced the intent NIH opened its first" Personal Computer ees and job performance needs, courses will of the Prize Foundation to award $1 million to User Resource Center on Feb. 11. be offered on several grade levels. the scientist or scientists who achieve a cure This 1s a ioint program effort by Division of One area of the center will be dedicated to for cancer. D Personnel Management, Division of Computer individual use of microcomputers and refer­ Research and Technology and lhe Division of ence holdings, while an adjoining room will Management Resources. be used for group instruction. The group Dr. Thomas E. Malone, Deputy Director. training area will also be available for demon­ Dr. Gallo Gets 3 Other Awards NIH; Calvin B. Baldwin. Associate Director lor strations, user groups and by individuals Dr Robert C. Gallo, chief of the Laboratory Administration and the Division Directors, when classes are not scheduled. of Tumor Cell Biology, Division of Cancer Edward Nicholas (DPM), Dr. Arnold W. Pratt Additional training programs, software and Treatment, National Cancer Institute, recently (DCRT) and George Russell (DMP) were resource materials will be added as the spe­ received three awards for distinguished given a tour and were presented with posters cific needs of BIDs are identified. The center achievement in cancer research. will work closely with the DMP office technol­ announcing the center. Dr. Gallo's laboratory discovered and isola­ The User Center will provide BIDs with a ogy coordinators, DCRT lead users program. ted HTLV-111 , a human RNA tumor virus that is wide range of office automation services fo­ and DPM training coordinators to maintain believed to be the cause of acquired immune cusing on \he administrative and scientific close contact with Institute needs and to as­ deficiency syndrome (AIDS). sist in both on and off-site program use of personal microcomputers, application He was recognized for his achievements in software and word processing. Included in development. science and medicine at the Fifth Biennial these services will be large and small group Employees who would like to learn or try out awards dinner of the National Italian Ameri­ training, tutorials. demonstrations and individ­ specific materials such as Lotus 1-2-3 and can Foundation on Sept. 15, 1984. Other ualized instruction programs. Wordstar will have the opportunity to set up honorees were: Daniel J. Travanti, actor: Gian an appointment with a tutor at the center. In­ In addition. a resource library 1s being de­ Carlo Menotti, composer: Sister Margherita veloped that will include magazines, articles struction will be provided either one-on-one or Marchione, biographer; and Arthur J. Decio, and catalogs as well as software demonstra­ 1n a small group. philanthropist. tion programs and a list of NIH users with ap­ The center slaff includes: George Z1ener plication experience using specific programs. and Brigid Noonan from DPM and George Established in 1922 Classes for large and small groups being Murray. Anna Perrone and Sue O'Boyle from offered during the next 3 months include: DMP. Dr. Gallo received the Lila Gruber Honor lead user training, taught by DCRT staff and a The center will be open on Fridays and Award for Cancer Research, given by the series of computer literacy, data base, and Mondays during February and will expand to American Academy of Dermatology, at the or­ spreadsheet courses, offered through DPM. 4 days a week starting Mar. 1. ganization's annual business meeting last De­ Classes are open to all employees. For more information, call George Ziener, cember. Established in 1972 by Murray To focus class content to different employ- director of the center, on 496-5025. D Gruber in memory of his wife, this yearly award of $10,000 is given to one or more sci­ entists who have made outstanding advances Social Security Benefits Given for Working Beyond 65 1n cancer research. Dr. Gallo was honored with this award "in recognition of his investi­ A person who returns to work after begin­ cent a month) for each year after 65 that the gations of problems related to cancer." · ning to get Social Security retirement benefits worker does not get benefits because of his On Dec. 11, 1984. Dr. Gallo received the may qualify for higher benefits because of the or her employment. This additional credit also Dickson Prize in Medicine from the University additional earnings, Walter Miller, Social Se­ increases the payments made to widows and of Pittsburgh. Two prizes, the Dickson Prize in curity district manager in Silver Spring. Md. widowers. " Mr. Miller says. Science awarded by Carnegie-Mellon Univer­ says. "It is not necessary for the worker or wid­ sity, and the Dickson Prize in medicine. were "Social Security automatically refigures the ows and widowers to contact Social Security established m 1969 by the estates of Dr. Jo­ benefits after the additional earnings are to take any action for the increases where seph Z. Dickson, and his wife, Agnes Fischer credited to the worker"s record. People possible," Mr. Miller said, "because refiguring Dickson, to honor America's leaders in sci­ should, however, tell Social Security if they is automatic." ence and medicine. D expect to earn more than the annual exempt Additional information about benefits may amount. be obtained from the Social Security Office lo­ "In addition. a worker's benelits can be in­ cated at 962 Wayne Ave, Silver Spring, Md. There are several good protections against temp­ creased by 3 percent a year ( '/, of 1 per- The telephone number is 352-0447. D tation but the surest is cowardice.- Mark Twain

February 26, 1985 The NIH Record Page 11 Dr. Hans Falk, Expert on Health Hazards, Dies ?t 6?; Cited as 'Distinguished Intellect,' Renowned Sc1ent1st Internationally known cancer researcher and environmental health science authority Dr. Hans L. Falk, 65, died on Jan. 29 at Rex Hospital in Raleigh, N.C., after a 5-year strug­ gle with cancer. clQ Cll Cll Z cl :ro Before his retirement in January 1984, he (l) - C'D - CU C ::i ::- was associate director of the Office of Health Q,) {) 3'2 ::- 2: ~~ ;:; .,; ro · 0 0 ,- )> Hazard Assessment at the National Institute (/) w ::i --t ::i:, -< - a.~!!!. I :I: .... of Environmental Health Sciences at Re­ - Cl) QC Q,) JJ S' i go 3: search Triangle Park, N.C. (/) s:: 0 (/) ;:; m cl - Q,) 0 ::- ::r :I: Z ~ ~ C --t Dr. Falk joined the Institute in 1968 as asso­ < (/) -< 3c(f) ciate director for laboratory research before !:; (/) -rv-ro 3: 0 ro ~Cll~< )> "Tl assuming his post as head of the Office of C a. 0 o n z (/) NW-ct> 1/l Health Hazard Assessment. His work with the ro 0 IV I m Institute and its sister agency the National .,, 0 ro :,:) Cancer Institute in Bethesda, Md., where l1e u, ~ < 8 3' 0 was associate scientific director for rn carcinogenesis. spanned nearly 20 years and 1/l was preceded by academic appointments at the University of California at Los Angeles, and the University of Southern California at Dr. Hans L. Falk Los Angeles. than a scientist at the top or the environmental Known throughout his career for his expan­ health science field We have lost a distin­ sive knowledge, his lively and subtle _wi t._ and guished intellect who could both understand his ability to convey and translate sc1enlif1c with total discipline the scientific complexities knowledge for the complete spectrum of of questions. and then also see the broader reading and listening audiences-from Nobel questions In a context of policy and human laureates to laymen. from Iournalists to mem­ values. His worli stands as part of the founda­ bers of Congress-Dr. Falk lent his vast tion for future studies of the environment and knowledge and incisive c ritical sense to its relation to health." scores of panels and committees These in­ Dr Falk is survived by his wife. Gabrielle cluded scientific testimony before various C., Raleigh: sons, Raymond W. and Donald congressional bodies and work with Federal H., both of Chapel Hill; Stephen T. or Durham; agencies, as well as official committees w1th1n and a sister, Eva Wulkan of Chicago, Ill. the World Health Organization and other inter- national groups. . Though continually involved with stormy Dr. Gerald Kanter Named and controversial subjects, he was noted for To NIGMS Advisory Council his steady professional skepticism and integ­ rity regardless of political cu_rrents or public Dr. Gerald S. Kanter has been appointed to feelings. He reviewed extensive literature and a 4-year term of the National Advisory Gen­ testified and wrote on a great array of envi­ eral Medical Sciences Council. He is associ­ ronmental health topics, a small sampling of ate dean for graduate studies and research which include air pollutiol"). tobacco smoking, and a professor of physiology at Albany Med­ pesticides, asbestos. various facets of rad1a­ ical College, N.Y. tIon exposure. carcinogenesis and birth Dr Kanter received a B.S. degree in chem­ defects. istry from Long Island University and a Ph.D. in physiology from the University of Dr. Falk ·authored and coauthored more than 100 scientific publications, some of Rochester. He has been on the faculty of Albany Medical College since 1952. During a which are the definitive overview studies of leave of absence in 1963 and 1964, he specific public health issues. His intellect served as a branch chief at the U.S. Army In­ went directly to the areas of potential error or stitute of Environmental Medicine in Natick, fallacious logic-and his sense of humor Mass. could make such insight ring, and on occa­ He Is a member of the American Physiolog­ sion, sting. ical Society, the Association of American He learned adversity early, emigrating from Medical Colleges, and the National Council Breslau, Germany, months before the Nazis of University Research Administrators. He is sealed the town. He lost family members to also a fellow of the American Association for Nazi terror the Advancement of Science. Dr. Falk was educated in London and Can­ The council, which meets three times a ada, receiving his Ph.D. m biochemistry al year is composed of leaders In the biological McGill University in 194 7, with a thesis on and medical sciences, education, and public steroid hormones. affairs. Its members review applications for Colleagues at NIEHS remember him for his research training grants and make recom­ rigor in researching and directing 1nvestiga­ mendations to the Secretary of the Depart­ lIons of healt11 hazards. his far-reaching com­ ment of Health and Human Services and the mand ol the literature, and his astute and deft Directors of the National Institutes of Health abilities in human relations. both within the In­ and the National Institute of General Medical stitute and in the scientific community at large Sciences on policy matters and science man­ power needs related to the lnstitute's Dr David P. Rall, NIEHS Director, said: programs. D "With his passing, we have lost even more US GOVfRNMEl-

Page 12 The NIH Record February 26, 1985