MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract 993 Antihypertensive Combina

MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Bayer Aktiengesellschaft & Filing Date: 5090 Leverkusen West Antihypertensive Combination F.Hoffmann-La Roche & Co. 03/12/1986 Rec Warrant signed on 993 Germany & 4002 Basel, Wef: 04/12/1985 Vide PT 993 Product Aktiengeschaft No. G675271 dt 21/08/1987 Switzerland Attn: SS & Co. 03/12/1986

Filing Date: F.Hoffman Roche + Co. Basel, 22/01/1987 Rec. Warrant signed on 996 Benzazecine Derivatives AKTIENGESELLSCHAFT Switzerland Wef: 23/01/1986 Vide PT 996 G676991 dt 21/08/1987 Att. S S & Co. 22/01/1987

Novo Alle, DK-2880 Filing Date: Novo-Nordisk A/S & Albright Bagsvaerd, Demark & 20/02/1987 Rec: Warrant signed on 997 Protected Enzyme Systems & Wilson Limited Albright & Wilson House, Wef: 20/02/1986 Vide PT 997 G677984 dt 18/10/1988 Attn: SS & Co. Hagley Road West 20/02/1987 Oldbury, Warley, West Midlands, England

Novartis AG (Novartis SA), Filing Date: Alpha-Heterocycle substituted (Novartis Inc.) Schwarzwaldallee 215, 06/03/1987 Rec: Warrant signed on 998 Wef: 07/03/1986 Vide PT 998 Tolunitriles Att. S S & Co. 4050 Basel, Switzerland G738323 dt 21/08/1987 06/031987 Compounds having a cognition Patent and Licensing adjuvant action, agents Filing Date: HOECHST Department, Building containing them, and the use 25/03/1987 Warrant signed on 1001 AKTIENGESELLSCHAFT K801, D65926 Frankfurt Wef: N/A Vide PT 1001 thereof for the treatment and Rec: G738376 dt 18/10/1988 Att: Dr G.M. Camilleri am Main, Federal prophylaxis of cognitive 25/03/1987 Republic of Germany dysfunctions.

Patent and Licensing Ethylene oxide/propylene oxide Department block copolymers for controlling Building K801 Filing Date: HOECHST foam in liquid pharmaceutical D65926 Frankfurt am 28/05/1987 Rec: Warrant signed on 1002 AKTIENGESELLSCHAFT Wef: N/A Vide PT 1002 formulations, pharmaceutical Main G795946 dt 30/12/1987 Att: Dr G.M. Camilleri formulations, and a process for Federal Republic of 28/05/1987 their preparation. Germany

2-Kanda-Mikura-Cho, Sankei Pharmaceutical B-Lactam compound, method Chiyoda-ku, Tokyo Company Limited & Nippon for preparing the same, Japan 3-25 & Hanazono- Pharmaceutical Filing Date: medicinal composition for Cho, Development Insittute 16/07/1987 Rec: Warrant signed on 1006 bacterially infectious disease Mukawa-machi, Wef: 21/07/1986 Vide PT 1006 Company Limited G850816 dt 18/10/1988 therapy containing the same and Yuufutsu-gun, Att. S S & Co. 16/07/1987 intermediates for synthesis of Hokkaido, Japan the same.

Filing Date: Molecular Structure of Diltiazem Piazza Duca D’Aosta 12, 04/11/1987 Rec: Schiapparelli Farmaceutici 1009 Hydrochloride. Milano 20124 G975168 dt Wef: N/A ABANDONED Vide PT 1009 S.p.A Italy 04/11/1987

New Pharmacologically active Filing Date: compounds, methods for the ORION- YHTYMA DY Saunatontunie 1,02200 26/11/1987 Rec: Warrant Signed on 1012 preparation thereof and Wef: 28/11/1986 Vide PT 1012 Att: S S & Co. Espoo, Finland H 000560 dt 18/10/1988 compositions containing the 26/11/1987 same.

Substitued aminopropionamides, a process D-6230 Frankfurt am Filing Date: Hoechst Aktiengesellshaft for their preparation, agents Main 80, 09/12/1987 Rec: 1014 Att. Dr G.M Camilleri. Wef: 12/12/1986 WITHDRAWN Vide PT 1014 containing them, and their use, Federal Republic of H 000578 and new intermediates Germany dt 09/12/1987 producted in their preparation.

F. Hoffmann La Roche AG Filing Date: Hydrocinnamic Acid Derivatives. 124-184 Attn: S S & Co. 06/07/1988 Warrant signed on 1023 Grezacherstrasse, 4002 Wef: 21/07/1987 Vide PT 1023 Rec: H238167 18/07/1989 Basel, Switzerland dt 06/07/1988 New use of Cathechol-o-methyl Filing Date: transferase (comt) inhibitors and ORION- YHTYMA DY Saunatontunie 1,02200 16/12/1988 Rec: Warrant signed 1031 Wef: 24/12/1987 Vide PT 1031 their physiologically acceptable Att: S S & Co. Espoo, Finland 462511 dt 04/10/1990 salts and Esters. 16/12/1988

Filing Date: Imperial Chemical Industries Imperial Chemical A method for the amplification of 01/08/1989 Rec: Warrant signed on 1043 PLC Attn: Dr T. House, Millbank, London Wef: 28/07/1988 Vide PT 1043 nucleotide sequences. H638957 dt 14/06/1990 Grech SW1P 3JF, England 01/08/1989

Minnesota Mining and Filing Date: Fluorocarbon Elastomers 3M Centre, Saint Paul, Manufacturing Company 18/08/1989 Warrant signed on 1045 crosslinked by ionizing Minnesota 55144-1000, Wef: 29/08/1988 Vide PT 1045 Att. J. Mifsud. Rec: H638977 14/06/1990 Radiation. U.S.A. dt 18/08/1989

Filing Date: 124, Grenzacherstrasse, F. Hoffmann-La Roche AG 30/10/1989 Rec: Warrant signed on 1049 Penicillanic Acid Derivatives Ch-4002 Basel, Wef: 31/10/1988 Vide PT 1049 Attn: S S & Co. H812053 dt 06/11/1990 Switzerland 30/10/1989

Elarges House, Filing Date: 6/12 Elarges Street, Glasco Gravy Limited 16/01/1990 Rec: Warrant signed on 1052 Furan Derivatives London WIY 8DH, Wef: N/A Vide PT 1052 Attn: S S & Co. H813582 dt 06/11/1990 England 16/01/1990

Minnesota Mining and 3M Centre, Saint Paul, Filing Date: Fluoroclastomer Composition Manufacturing Company Minnesota 55144-1000, 24/05/1990 Warrant signed on 1061 with improved Bonding Wef: 22/06/1989 Vide PT 1061 Attn: Mr J. Mifsud U.S.A. Rec: H977738 dt 08/04/1991 Properties 24/05/1990

Filing Date: Plasmids, their construction and 5100 –Aachen, 28/06/1990 Rec: Grunenthal Gmbh Warrant signed on 1063 their use in manufacture of a Federal Republic of J036803 dt Wef: 19/07/1989 Vide PT 1063 Att. Joseph Mifsud. 08/04/1991 plasminogen activator. Germany 28/06/1990 Pholos N.V Filing Date: Process for the continuous De Ruyten Kade 62, A Company of the 12/10/1990 Rec: Warrant signed on 1070 production of high molecular Curacao, Wef: 13/10/1989 Vide PT 1070 Netherlands Antilles J162919 dt 30/06/1991 Weight polyester resin. Netherlands Antilles Att. S S & Co. 12/10/1990

3M Centre, Saint Paul, Filing Date: Minnesota Mining and Minnesota 55144-1000, 05/11/1990 Rec: Warrant signed on 1073 Polymer Blend Composition. Manufacturing Company Wef: 16/11/1989 Vide PT 1073 U.S.A. J162958 dt 30/06/1991 Attn: B&M Patentbureau 05/11/1990

Filing Date: 124 Grenzacherstrasse, F.Hoffman--La Roche AG 15/11/1990 Rec: Warrant signed on 1075 Amino Acid Derivatives. CH-4002 Basel, Wef: 11/12/1989 Vide PT 1075 Att. S S & Co. J162987 dt 31/07/1991 Switzerland 15/10/1990

Novartis AG (Novartis SA), Filing Date: (Novartis Inc) Schwarzwaldallee 215, 14/12/1990 Rec Warrant signed on 1076 Hemihydrate Wef: 12/01/1990 Vide PT 1076 Attn: S S & Co. 4058 Basel, Switzerland : J205524 dt 30/09/1991 14/12/1990

Filing Date: 4 Sea Rays Court, Polmer material for Ophthalmic Italtrade Medical Co. Ltd. 27/02/1991 Rec: Warrant signed on 1080 Zonqor Street, Wef: N/A Vide PT 1080 Optical Elements. Attn: N/A J318202 dt 30/09/1991 Marsascala, Malta 27/02/1991

Filing Date: The B.F. Goodrich Company 39225, Embassy Pyridinium Metathesis Catalysts 03/04/1991 Rec: Warrant signed on 1084 Attn: R. Frendo Randon & Parkway, Akron, Ohio Wef: N/A Vide PT 1084 for Cycloolefin Polymerization. J362602 dt 15/10/1991 Associates 4433-1799, U.S.A. 03/04/1991

Tour Maine Filing Date: Montparnasse, 33 Jouveinal S.A 21/06/1991 Warrant signed 1089 Lotion and its preparation. Avenue du Maine, Wef: 26/06/1990 Vide PT 1089 Attn: Mr C. Grech Orr Rec: J396258 dt 30/04/1993 75755 Paris Cedex 15, 21/06/1991 France MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Filing Date: Nippon Zeon Co. Ltd. 6-1 Marunouchi 2- Bulk Polymerizable 26/11/1991 Warrant signed on 1101 Attn: R Frendo Randon & chome, Chiyodo-ku, Wef: 28/11/1990 Vide PT 1101 Reaction Solutions Rec: 734408 dt 30/09/1992 Associates Tokyo 100, Japan 26/11/1991

6744 Upper 33rd Street Filing Date: Curing Fluorocarbon Dyneon LLC North, 30/12/1991 Warrant signed on 1104 Wef: 11/01/1991 Vide PT 1104 Elastomers Attn: B&M Patentbureau Oakdale, Minnesota Rec: I734449 dt 28/08/1992 55128, U.S.A. 30/12/1991

25 Sundridge Road, Filing Date: Pharmaceutical Dr.Washington Odur Ayuko Kingstanding, 14/02/1992 Warrant signed on 1106 Wef: 13/02/1991 Vide PT 1106 Composition Attn: B&M Patentbureau Birmingham B44 9NY, Rec: J807684 dt 21/10/1993 Great Britian 13/02/1992

Filing Date: 124 Grenzacherstrasse, Polyethlen-Protein F.Hoffman-La Roche AG 23/03/1992 Warrant signed on 1110 CH-4002 Basel, Wef: 25/03/1991 Vide PT 1110 Conjugates. Att. S S& Co. Rec: I910210 dt 30/09/1992 Switzerland 23/03/1992

A Particular Mineral Salt Filing Date: Composition And a Sunchemie Malta Ltd. 18/1 South Street, 04/09/1992 Warrant signed on 1116 Wef: N/A Vide PT 1116 Process for Making The Attn: S S & Co. Valletta, Malta Rec: K103294 dt 21/10/1993 Same. 11/091992

3M Centre, Saint Paul, Filing Date: Minnesota Mining and Methanol Resistant Minnesota 55144-1000, 03/11/1992 Warrant signed on 1123 Manufacturing Company Wef: 17/12/1991 Vide PT 1123 Fluorocarbon Elastomers U.S.A. Rec: K198614 dt 27/10/1993 Attn: B&M Patentbureau 03/11/1992

P.O Box 1043, Cardinal Filing Date: Quinilone -And- Avenue, Atlantic Industries 07/12/1992 Warrant signed on 1125 Naphthyridone-Carboxyic Georgetown, Grand Wef: 10/01/1992 Vide PT 1125 Attn: S S & Co. Rec: K198723 dt 21/10/1993 Acid Derivatives. Cayman, Cayman 07/12/1992 Islands, BWI

Villa Esmeralda' Filing Date: Method of processing and Mr. Jean-Marc Triq il-Palm 24/05/1993 Warrant signed on 1143 preparing vegetables, to Demeulemeester Att. Wef: N/A Vide PT 1143 San Marija Estate Rec: K487229 dt 24/01/1994 extend their shelf life. Dr Henry C. Vassallo Mellieha, Malta 24/05/1993 3M Centre, Saint Paul Filing Date: Minnesota Mining and Polymer Blend Minnesota 55144-1000, 31/05/1993 Warrant signed on 1145 Manufacturing Company Wef: 18/06/1992 Vide PT 1145 Compositions U.S.A. Rec: K487240 dt 15/06/1994 Att. Mr J. Mifusd 31/05/1993

Filing Date: BIOGAL Skin regenerating Pallegi u13, Debrecen, 26/07/1993 Warrant signed on 1147 GYOGYSEZERGYAR BT Wef: 28/07/1992 Vide PT 1147 Cosmetic Composition H-4042, Hungary Rec: K623081 dt 15/06/1994 Att. Dr D. Tonna 26/07/1993

Filing Date: 124 Grenzacherstrasse, F.Hoffman-La Roche AG 09/08/1993 Warrant signed on 1148 PEG-Interferon Conjugates Ch-4002 Basel, Wef: 26/08/1992 Vide PT 1148 Attn: SS & Co. Rec: K623340 dt 15/06/1994 Switzerland 09/08/1993

Filing Date:

Fluoroelatomer 09/09/1993 Dyneon LLC 6744, Upper 33rd Street Warrant signed on 1149 Composition with Rec: K623353 dt Wef: 24/08/1992 Vide PT 1149 Attn: B&M Patentbureau North Oakdale, 15/06/1994 urgeronium Compounds 09/09/1993 Minnesota 55128 U.S.A.

Filing Date: Fluorine-containing Minnesota Mining and 3M Centre, Saint Paul, 11/02/1994 Warrant signed on 1155 polymers and preparation Manufacturing Company Minnesota 55144-1000, Wef: 23/03/1993 Vide PT 1155 Rec: K875570 dt 30/09/1994 and use thereof Attn. Mr. J Mifsud. U.S.A. 11/02/1994

Bifunctional variants of Filing Date: urokinase with improved Zieglerstrasse 6, Grunenthal GMBH 12/04/1994 Warrant signed on 1161 Sibrino-lytic properties D-52078 Aachen, Wef: 15/07/1993 Vide PT 1161 Att. Mr. J. Mifsud Rec: K986480 dt 28/02/1995 and thrombin-inhibiting Germany 12/04/1994 activity

Filing Date: 124 Grenzacherstrasse, F.Hoffman-La Roche AG 14/04/1994 Warrant signed on 1162 Cephalosporin Derivatives Ch-4002 Basel, Wef: 16/04/1993 Vide PT 1162 Att. S S & Co. Rec: K985377 dt 25/07/1995 Switzerland 14/04/1994

Filing Date: Carnbee, Anstruther, Margaret Louise Carstairs 29/04/1994 Warrant signed on 1166 Compositions FIFE KY 10 2 LT, Wef: 01/05/1993 Vide PT 1166 Attn: S S & Co. Rec: L038414 dt 28/02/1995 Scotland 29/04/1994

Filing Date: 17 Bond Street, St. Radopath Limited 23/05/1994 Warrant signed on 1170 Arylating agents Helier, Jersey, Wef: 21/05/1993 Vide PT 1170 Attn: Rec: L038465 dt 28/02/1995 Channel Islands 23/05/1994

Filing Date: 17 Bond Street, St. Radopath Limited 18/10/1994 1185 Anti-Viral agents Helier, Jersey, Wef: 19/10/1993 WITHDRAWN Vide PT 1185 Attn: B&M Patentbureau Rec: L304127 dt Channel Islands 18/10/1994 Filing Date: A61 Marsa Industrial Amino Chemicals Ltd. Attn: 09/11/1994 1186 Synthesis of Pentoxifylline Estate, Marsa HMR 15, Wef: N/A ABANDONED Vide PT 1186 N/A Rec: L304165 dt Malta 09/11/1994

Filing Date: Synthesis of A61 Marsa Industrial Amino Chemicals Ltd. Attn: 09/11/1994 1187 Medroxyprogesterone Estate, Marsa HMR 15, Wef: N/A ABANDONED Vide PT 1187 N/A Rec: L304165 dt Acetate Malta 09/11/1994

Filing Date: A61 Marsa Industrial Synthesis of Ambioxol Amino Chemicals Ltd. Attn: 09/11/1994 1188 Estate, Marsa HMR 15, Wef: N/A ABANDONED Vide PT 1188 Hydrochloride N/A Rec: L304165 dt Malta 09/11/1994

Crystalline N-acetyl Filing Date: Biota Scientific 1601 Malvern Road, neurominic acid 16/12/1994 Warrant signed on 1195 Management Pty Ltd Attn: Glen Iris, Wef: 17/12/1993 Vide PT 1195 derivatives and processes Rec: L305442 dt 12/01/1996 Lysaght & Co. Victoria, 3146 Australia for their preparation 16/12/1994 MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Tetracyclic derivatives, Filing Date: 09/03/1995 ICOS Corporation 43, Rue Vineuse 75016 Warrant signed on 1201 process of preparation and Rec: 474086 dt Wef: N/A Vide PT 1201 Attn: Lysaght & Co. Paris, France 11/06/1996 use 09/03/1995

New erythromcycin derivatives, process for their Filing Date: 07/04/1995 preparation, pharmaceutical Aventis Pharma S.A. 20 Avenue Raymond Aron, 92/60 Warrant signed on 1205 Rec: L475968 dt Wef: 08/04/1994 Vide PT 1205 compositions containing Attn: S S & Co. Antony, France. 11/06/1996 07/04/1995 them, and their use as medicaments

Minnesota Mining and Fluorine-containing Filing Date: 01/12/1995 Manufacturing Company 3M Center, Saint Paul, Minnesota Warrant signed on 1220 polymers and preparation Rec: L856080 dt Wef: 14/12/1994 Vide PT 1220 Attn: B&M Patentbureau 55144-1000, U.S.A. 31/05/1999 thereof 01/12/1995

Prof. Dott. Domenico Filing Date: 27/11/1996 The Therapy of acquired Via Pizzi 14 Bagno a Ripoli 1247 Acorfora Rec: M250214 dt Wef: N/A WITHDRAWN Vide PT 1247 immunodeficiency (Florence), Italy Att. S S & Co. 27/11/1996

Glaxo Wellcome House, Filing Date: 28/10/1997 Pharmaceutical Glaxo Group Limited Berkeley Avenue, Warrant signed on 1293 Rec: M417571 dt Wef: 31/10/1996 Vide PT 1293 compositions Attn: Lysaght & Co. Greenford, 28/12/1998 28/10/97 Middlesex, UB6 ONN, England

Glaxo Wellcome House, Filing Date: 10/12/1997 Peptides and compounds Glaxo Group Limited Berkeley Avenue, Warrant signed on 1294 Rec: M417727 of Wef: 11/12/1996 Vide PT 1294 that bind to a receptor Attn: Lysaght & Co. Greenford, 28/12/1998 10/12/1997 Middlesex, UB6 ONN, England

A product designed to destroy human Professore Dottore Domenico Filing Date: 23/01/1998 Via Pizzi 14, Bagno a Ripoli Warrant signed on 1299 immunodeficiency virus and Acorfora Att. S Rec: M417895 dt Wef: N/A Vide PT 1299 (Florence), Italy 26/06/1998 method of administrating S & Co. 23/01/1998 the same

Glaxo Wellcome House, Filing Date: 27/02/1998 Glaxo Group Limited Berkeley Avenue, Warrant signed on 1301 Pyrazine Compounds Rec: N244755 dt Wef: 01/03/1997 Vide PT 1301 Att: Lysaght & Co. Greenford, 30/11/2000 27/02/1998 Middlesex, UB6 ONN, England Glaxo Wellcome House, Filing Date: 23/03/1998 Pharmaceutical Glaxo Group Limited Warrant signed on 1305 Berkeley Avenue, Greenford, Rec: N244838 dt Wef: 24/03/1997 Vide PT 1305 Compositions Attn: Lysaght & Co. 30/09/1999 Middlesex, UB6 ONN, England 23/03/1998

Monastero Santa Maria, Filing Date: 25/03/1998 Gaudi Eliseo 1306 RCK Valdedios, Villaviciosa Asturias, Rec: N244791 dt Wef: N/A ABANDONED Vide PT 1306 Attn: N/A Spain 25/03/1998

Therapeutical method for action against all forms of Monastero Santa Maria, Filing Date: 25/03/1998 Gaudi Eliseo 1307 Degerative Diseases based Valdedios, Villaviciosa Asturias, Rec: N244791 dt Wef: N/A ABANDONED Vide PT 1307 Attn: N/A on the action of anti- Spain 25/03/1998 oxidants

Glaxo Wellcome House, Filing Date: 18/05/1998 Glaxo Group Limited Warrant signed on 1313 A novel salt Berkeley Avenue, Greenford, Rec: N244986 dt Wef: 17/05/1997 Vide PT 1313 Attn: Lysaght & Co. 30/06/1999 Middlesex, UB6 ONN, England 18/05/1998

20, Clamwilliam Terrace, Filing Date: 21/05/1998 Clear, injectable formulation Westy AG Warrant signed on 1314 Aeulestrasse 74, Vaduz Rec: N245049 dt Wef: 26/05/1997 Vide PT 1314 of an anesthetic compound. Attn: SS & Co. 31/07/2000 Liechtenstein 21/05/1998

Filing Date: 27/08/1998 Pyrazolopyrimidinones for Pfizer Limited Ramsgate Road, Sandwich, Kent Warrant signed on 1322 Rec: N245431 dt Wef: N/A Vide PT 1322 the treatment of impotence Attn: Lysaght & Co. CT 13 9NJ, England 31/05/1999 27/08/1998

Glaxo Wellcome House, Filing Date: 22/12/1998 Glaxo Group Limited Warrant signed on 1329 Triazine Compounds Berkeley Avenue,Greenford, Rec: P027242 dt Wef: 22/12/1997 Vide PT 1329 Attn: Lysaght & Co. 30/03/2000 Middlesex, UB6 ONN, England 22/12/1998

Inherently light-and-heat- Filing Date: 12/02/1999 BASF Aktiengesellschaft 67056 Ludwigshafen, Warrant signed on 1333 stabilised Polyamide and Rec: P027372 dt Wef: 13/02/1998 Vide PT 1333 Attn: S S & Co. Federal Republic of Germany 29/10/1999 method of making the same 12/02/1999

Filing Date: 23/02/1999 BASF Aktiengesellschaft 67056 Ludwigshafen, Warrant signed on 1335 Production of Polyamides Rec: P027621 dt Wef: 26/02/1998 Vide PT 1335 Att. S S & Co. Federal Republic of Germany 31/07/2000 23/02/1999

3000 Continental Drive, North, Filing Date: 26/02/1999 Light and thermally stable BASF Corporation Warrant signed on 1336 New Jersey 07828-1234, United Rec: P027457 dt Wef: 09/03/1998 Vide PT 1336 polyamide Attn: S S & Co. 31/07/2000 States of America. 26/02/1999 Inherently light-and heat- Filing Date: 16/03/1999 BASF Aktiengesellschaft 67056 Ludwigshafen, Warrant signed on 1338 stabilised polyamides of Rec: P027399 dt Wef: 20/03/1998 Vide PT 1338 Att. S S & Co. Federal Republic of Germany 29/10/1999 improved wet fastness. 16/03/1999

Glaxo Wellcome House, Filing Date: 13/04/1999 Process for the synthesis of Glaxo Group Limited Warrant signed on 1342 Berkeley Avenue, Greenford, Rec: P027677 dt Wef: N/A Vide PT 1342 chloropurine intermediates Attn: Lysaght & Co. 15/02/2000 Middlesex UB6 ONN, England 13/04/1999

235 East 42nd Street, Filing Date: 12/07/1999 Pfizer Inc. Warrant signed on 1349 FKBP inhibitors New York, New York 10017 Rec: P028050 dt Wef: 20/07/1998 Vide PT 1349 Att: Lysaght & Co. 27/07/2000 United States of America. 12/07/1999

2-substituted-1-Piperidyl 235 East 42nd Street, Filing Date: 12/07/1999 Pfizer Inc. Warrant signed on 1350 Benzimidazole compounds New York, New York 10017 Rec: P028051 dt Wef: 06/08/1998. Vide PT 1350 Att: Lysaght & Co. 27/07/2000 as Orl 1-Receptor agonists United States of America. 12/07/1999

Solid oral dosage form MERCK SANTE Filing Date: 14/07/1999 comprising a combination of 37, Rue Saint-Romain 69008, Warrant signed on 1351 Att: Mr J. Mifsud. Rec: P028054 dt Wef: 15/07/1998. Vide PT 1351 metformin and LYON, FRANCE 31/07/2000 14/07/1999 glibenclamide

Calcium (3S) tetrahydro-3- furaryl (IS, 2R)-3-[[ (4- Glaxo Wellcome House, Filing Date: 14/07/1999 aminopheryl) sulforyl] Glaxo Group Limited Warrant signed on 1352 Berkeley Avenue, Greenford, Rec: P028055 dt Wef: 18/0719/98 Vide PT 1352 (isolatyl) amino]-1-benzyl- Attn: Lysaght & Co. 31/07/2000 Middlesex UB6 ONN, England 14/07/1999. 2(phosphenoxy) proplycarbamate

Heterocyclic compounds as 235 East 42nd Street, New York, Filing Date: 14/07/1999 Pfizer Inc. Warrant signed on 1353 inhibitors of potamase New York 10017, United Rec: P028056 dt Wef: 21/07/1998 Vide PT 1353 Attn: Lysaght & Co. 15/02/2000 enzymes States of America 14/07/1999

Phthalazine derivatives via della Chimica 9, I/36100 Filing Date: 16/07/1999 Zambon Group S.p.A Warrant signed on 1354 phosphodiesterase 4 Vicenza, Italy Rec: P028072 dt Wef: 21/07/1998 Vide PT 1354 Attn: S S & Co. 27/07/2000 inhibitors. 16/07/1999

235 East 42nd Street, New York, Filing Date: 23/07/1999 Pfizer Inc. Warrant signed on 1356 Isoquinodines New York 10017, United Rec: P258009 dt Wef: 24/07/1998 Vide PT 1356 Attn: Lysaght & Co. 28/07/2000 States of America. 23/07/1999 Eastern Point Road, Groton, Filing Date: 29/07/1999 1-aryl-3-arylmethyl-1, 8- Pfizer Products Inc. Warrant signed on 1357 Connecticut 06340, United States Rec: P258021 dt Wef: 11/08/1998 Vide PT 1357 nephthyridn-4 (IH)-ones. Attn: Lysaght & Co. 31/07/2000 of America. 29/07/1999.

Eastern Point Road, Groton, Filing Date: 29/07/1999 Pfizer Inc Warrant Signed on 1358 Tace Inhibotors Connecticut 06340, United States Rec: P258022 dt Wef: 12/08/1998 Vide PT 1358 Att: Lysaght & Co. 31/07/2000 of America. 29/07/1999.

Eastern Point Road, Groton, Filing Date: 03/08/1999 Hydroxy pipecolate Pfizer Inc Warrant Signed on 1361 Connecticut 06340, United States Rec: P258107 dt Wef: 12/08/1998 Vide PT 1361 hydroxamic acid derivatives Att: Lysaght & Co. 27/07/2000 of America. 03/08/1999

Eastern Point Road, Groton, Filing Date: 03/08/1999 New Pharmaceutical Uses Pfizer Products Inc Warrant Signed on 1362 Connecticut 06340, United States Rec: P258108 dt Wef: 11/08/1998 Vide PT 1362 for NOS inhibitors Att: Lysaght & Co. 27/07/2000 of America. 03/08/1999

Alkynyl-substituted quinolin- Eastern Point Road, Groton, Filing Date: 18/08/1999 Pfizer Products Inc Warrant Signed on 1364 2-0ne derivatives useful as Connecticut 06340, United States Rec: P258133 dt Wef: 27/08/1998 Vide PT 1364 Att: Lysaght & Co. 01/06/2000 anticancer agents of America. 18/08/1999

Eastern Point Road, Groton, Filing Date: 18/08/1999 Polymorph of zopolrestat Pfizer Products Inc Warrant Signed on 1365 Connecticut 06340, United States Rec: P258134 dt Wef: 21/08/1998 Vide PT 1365 monohydrate Att: Lysaght & Co. 01/06/2000 of America. 18/08/1999

Eastern Point Road, Groton, Filing Date: 18/08/1999 Quinolin-2-one derivatives Pfizer Products Inc Warrant Signed on 1366 Connecticut 06340, United States Rec: P258135 dt Wef: 27/08/1998 Vide PT 1366 useful as anticancer agents Att: Lysaght & Co. 01/06/2000 of America. 18/08/1999

Eastern Point Road, Groton, Filing Date: 25/08/1999 4,4-biarylpiperidine Pfizer Products Inc Warrant Signed on 1367 Connecticut 06340, United States Rec: P258071 dt Wef: 09/09/1998 Vide PT 1367 derivatives Att: Lysaght & Co. 28/07/2000 of America. 25/08/1999

Pharmaceutical agents for Filing Date: 07/09/1999 the treatment of Parkinson's Pfizer Products Inc Eastern Point Road Warrant Signed on 1371 Rec: P258181 dt Wef: 21/09/1998 Vide PT 1371 disease, ADHD and Att: Lysaght & Co. Groton, Connecticut 06340, 18/09/2000 07/09/1999 microadenomas U.S.A. 4-amino substituted-2- Filing Date: 10/09/1999 Pfizer Products Inc Eastern Point Road Warrant Signed on 1372 substituted-1,2,3,4- Rec: P258/95 dt Wef: 17/09/1998 Vide PT 1372 Att: Lysaght & Co. Groton, Connecticut 06340, 31/07/2000 tetrahydroquinolines 10/09/1999 U.S.A.

Filing Date: 10/09/1999 4-caboxyamino-2-methyl- Pfizer Products Inc Eastern Point Road Warrant Signed on 1373 Rec: P258196 dt Wef: 17/09/1998 Vide PT 1373 1,2,3,4-tetrahydroquinolines Att: Lysaght & Co. Groton, Connecticut 06340, 31/07/2000 10/09/1999 U.S.A.

4-caboxyamino-2- Filing Date: 10/09/1999 Pfizer Products Inc Eastern Point Road Warrant Signed on 1374 substituted-1,2,3,4- Rec: P258197 dt Wef: 17/09/1998 Vide PT 1374 Att: Lysaght & Co. Groton, Connecticut 06340, 31/07/2000 tetrahydroquinolines 10/09/1999 U.S.A.

Filing Date: 17/09/1999 Warrant Signed on Carbamate and carbazate Pfizer Products Inc Eastern Point Road 1376 Rec: P258217 dt Wef: 22/09/1998 12/09/2000 Vide PT 1376 ketolide antibiotics Att: Lysaght & Co. Groton, Connecticut 06340, 17/09/1999 U.S.A.

Trans-6-[2-(3-or4- carboxamido-substituted Filing Date: 24/09/1999 pyrinol-1-YL)alkyl]-4- Warner-Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1379 Rec: P258242 dt Wef: N/A Vide PT 1379 hydroxypy-ran-2-one Att: Lysaght & Co New Jersey 07950, USA 31/07/2000 24/09/1999 inhibitors of cholesterol synthesis

[R-(R*R*)]-2-(4-Fluorophenyl)- B,dihydroxy-5-(1-methylethyl- 3-phenyl-4- Filing Date: 24/09/1999 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1380 (phenylamino)carbonyl]-1H- Rec: P258243 dt Wef: N/A Vide PT 1380 Att: Lysaght & Co New Jersey 07950, USA 31/07/2000 pyrrole-1-heptanoic acid, it's 24/09/1999 lactane form and salts thereof

Crystalline[R-(R*,R*)]-2-(4- fluorophenyl)-B,8-dihydroxy- Filing Date: 24/09/1999 5-(1-methylethyl)-3-phenyl-4- Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1381 Rec: P258244 dt Wef: N/A Vide PT 1381 [phenylamino)carbonyl]-1H- Att: Lysaght & Co New Jersey 07950, USA 31/07/2000 24/09/1999 pyrrole-1-heptanoic acid calcium salt (2:1)

Stable oral C1-981 Filing Date: 24/09/1999 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1382 formulation and process pf Rec: P258245 dt Wef: N/A Vide PT 1382 Att: Lysaght & Co New Jersey 07950, USA 31/07/2000 preparing same 24/09/1999 PO Box 497 Cardiff, CFI 3XR United Kingdom Patents and University College Cardiff Licensing company of Cardiff Filing Date: 24/09/1999 Warrant Signed on 1383 Chemical compound Consultants Limited University, Rega Foundation, Rec: P258246 dt Wef: 28/09/1998 Vide PT 1383 27/07/2000 Att: S S & Co. Minderoedistraat, 10 24/09/1999 B-3000, Leuvon Belgium

Process for Preperation of Pfizer Overseas Filing Date: 06/10/1999 Pyrazolo (4,3-d) Pyrimidin-7- Pottery Road, Dun Laoghaine, Warrant signed on 1389 Pharmaceutical Rec: P258315 dt Wef: 12/10/1998 Vide PT 1389 ones and Intermediates County Dublin 07/11/2000 Attn: Lysaght & Co. 06/10/1999 thereof

235 East 42nd Street, New York, Filing Date: 06/10/1999 Pfizer Inc Warrant signed on 1390 Adenine Derivatives NY 10017, United States of Rec: P258316 of Wef: 16/10/1998 Vide PT 1390 Att: Lysaght & Co. 25/11/2000 America 06/10/1999

Filing Date: 12/10/1999 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1391 Sertraline oral concentrate Rec: P258259 dt Wef: 13/10/1998 Vide PT 1391 Att: Lysaght & Co. Connecticut 06340, USA 25/11/2000 12/10/1999

Pfizer Research & Development Company N.V/ La Touche House International Filing Date: 12/10/1999 Controlled-release Warrant signed on 1392 SA Financial Service Centre, Dublin, Rec: P258260 dt Wef: 23/10/1998 Vide PT 1392 pharmaceutical formulations 07/11/2000 Attn: Lysaght & Co Ireland 12/10/1999

Filing Date: 12/10/1999 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1393 Novel macrolide antibiotics Rec: 258261 dt Wef: 03/11/1998 Vide PT 1393 Att: Lysaght & Co. Connecticut 06340, USA 25/11/2000 12/10/1999

5HT1 Receptor Agonists and Filing Date: 12/10/1999 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1394 Metoclopramide for the Rec: 258262 dt Wef: 30/10/1998 Vide PT 1394 Att: Lysaght & Co. Connecticut 06340, USA 07/11/2000 treatment of migraine 12/10/1999

Pyrazolopyrimidinone cGMP 235 East 42nd Street, New York, Filing Date: 12/10/1999 PDE5 inhibitors for the Pfizer Inc Warrant signed on 1395 NY 10017, United States of Rec: P258263 dt Wef: 23/10/1998 Vide PT 1395 treatment of sexual Att: Lysaght & Co. 12/09/2000 America 12/10/1999 Dysfunction MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, 11/11/1999 Wef: 02/12/1998 Warrant signed on 1401 Hygromycin A derivatives Vide PT 1401 Att: Lysaght & Co. Connecticut 06340, Rec: P258457 dated 25/11/2000 U.S.A. 11/11/1999

Eastern Point Road, Filing Date: 3,3-Biarylpiperdine and 2,2- Pfizer Products Inc. Groton, 11/11/1999 Warrant signed on 1403 Wef: 29/12/1998 Vide PT 1403 biarylmerpholine derivatives. Att: Lysaght & Co. Connecticut 06340, Rec: P258458 dt 31/01/2001 U.S.A. 11/11/1999

235 East 42nd Street, Filing Date: Pfizer Inc. New York, New York 11/11/1999 Warrant signed on 1404 Indole derivatives Wef: 27/11/1998 Vide PT 1404 Att: Lysaght & Co. 10017, United States of Rec: P258459 dt 25/11/2000 America. 11/11/1999

Eastern Point Road, Filing Date: 5HT1 antagonists for Pfizer Products Inc. Groton, 16/11/1999 Warrant signed on 1405 Wef: 28/12/1998 Vide PT 1405 antidepressant therapy Attn: Lysaght & Co. Connecticut 06340, Rec: 258398 dt 07/02/2001 United States of America. 16/11/1999

Filing Date: 5200 Old Orchard Road, G.D. Searle + Co. 29/11/1999 Warrant signed on 1407 Celecoxib Compositions. Skokie, Illinois 60077, Wef: 30/11/1998 Vide PT 1407 Attn: S S & Co. Rec: P258515 dt 21/08/2002 U.S.A 29/11/1999

Eastern Point Road, Filing Date: Carbamate and Carbazate Pfizer Products Inc. Groton, Connecticut 01/12/1999 Warrant signed on 1408 Wef: 10/12/1998. Vide PT 1408 Ketolide antibiotics. Attn: Lysaght & Co. 06340, United States of Rec: P258610 dt 31/01/2001 America 01/12/1999

235 East 42nd Street, Filing Date: Pfizer Inc. New York, 09/12/1999 Warrant signed on 1409 CCR5 Modulators. Wef: 23/12/1998 Vide PT 1409 Attn: Lysaght & Co. New York 10017, Rec: P258529 dt 22/02/2001 United States of America. 09/12/1999.

Eastern Point Road, Filing Date: Substituted bicyclic derivatives Pfizer Products Inc. Groton, Connecticut 09/12/1999 Warrant signed on 1410 Wef: 27/01/1999 Vide PT 1410 useful as anticancer agents Attn: Lysaght & Co. 06340, United States of Rec: P258530 dt 31/01/2001 America 09/12/1999.

Filing Date: Drug delivery devices and Virodene Pharmaceutical 607, 21st Avenue 16/12/1999 methods for treatment of viral Holdings (Proprietary) Warrant signed on 1411 Rietfontein, 0084, Rec: P258546 dt Wef: N/A Vide PT 1411 and microbial infections and Limited 28/07/2000 Republic of South Africa 16/12/1999 waisting syndromes. Attn: S S & Co. 235 East 42nd Street, Filing Date: Pfizer Inc. New York, 22/12/1999 Warrant signed on 1413 CCR5 modulators Wef: 23/12/1998 Vide PT 1413 Attn: Lysaght & Co. New York 10017, Rec: P258736 dt 31/01/2001 United States of America 22/12/1999

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, Connecticut 29/12/1999 Warrant signed on 1414 Ketolide antibiotics Wef: 27/01/1999. Vide PT 1414 Attn: Lysaght & Co. 06340, United States of Rec: P258748 dt 31/01/2001 America 29/12/1999

67056 Filing Date: Use of heterogeneous catalysts BASF Aktiengesellschaft Ludwigsheften, 12/01/2000 Warrant signed on 1415 in processes for producing Wef: 13/01/1999 Vide PT 1415 Attn: S S & Co. Federal Republic of Rec: P258657 dt 12/09/2000 polyamides. Germany. 12/01/2000

Filing Date: Eastern Point Road, Heteroaryl-substituted quinolin-2- 09/02/2000 Pfizer Products Inc. Groton, Warrant signed on 1421 one derivatives useful as Rec: P258807 dt Wef: 11/02/1999 Vide PT 1421 Attn: Lysaght & Co. Connecticut 06340, 23/03/2001 anticancer agents. 09/02/2000 United States of America.

Eastern Point Road, Filing Date: Monoamine reuptake inhibitors Pfizer Products Inc. Groton, Connecticut 09/02/2000 Warrant signed on 1422 Wef: 23/02/1999 Vide PT 1422 for treatment of CNS disorders. Attn: Lysaght & Co. 06340, United States of Rec: P258808 dt 30/04/2001 America 09/02/2000.

Eastern Point Road, Filing Date: 2-aminopyridines containing Pfizer Products Inc. Groton, Connecticut 17/02/2000 Warrant signed on 1423 Wef: 25/02/1999 Vide PT 1423 fused ring substituents. Attn: Lysaght & Co. 06340, United States of Rec: P258688 dt 30/04/2001 America 17/02/2000

Eastern Point Road, Filing Date: Process for preparing growth Pfizer Products Inc. Groton, Connecticut 25/02/2000 Warrant signed on 1424 Wef: 26/02/1999 Vide PT 1424 hormone secretagogues. Attn: Lysaght & Co. 06340, United States of Rec: P258848 dt 23/03/2001 America 25/02/2000

Eastern Point Road, Filing Date: Oxamic acids and derivatives as Pfizer Products Inc. Groton, Connecticut 25/02/2000 Warrant signed on 1425 Wef: 01/03/1999 Vide PT 1425 thyroid receptor ligands Attn: Lysaght & Co. 06340, United States of Rec: P258849 dt 23/03/2001 America 25/02/2000

235 East 42nd Street, Filing Date: 1,2,3,4, - tetrahydro-1- Pfizer Inc. New York, 01/03/2000 Warrant signed on 1427 nephthalenam compounds useful Wef: 01/03/1999 Vide PT 1427 Attn: Lysaght & Co. New York 10017, Rec: P410024 dt 23/03/2001 in therapy United States of America. 01/03/2000 Eastern Point Road, Groton, Connecticut Filing Date: Processes and intermediates for Pfizer Products Inc. & OSI 06340, United States of 01/03/2000 Warrant signed on 1428 preparing anti-cancer PHARMACEUTICALS INC. America & Suite 110 Wef: 31/03/1999 Vide PT 1428 Rec: P410025 dt 30/04/2001 compounds. Attn: Lysaght & Co. 58, South Service Road 01/03/2000 Melville, New York 11747, United States of America

235 East 42nd Street, Filing Date: Pfizer Inc. New York, 21/03/2000 Warrant signed on 1429 Resorcinol derivatives. Wef: 22/03/1999. Vide PT 1429 Attn: Lysaght & Co. New York 10017, Rec: P258898 dt 30/04/2001 United States of America 21/03/2000

235 East 42nd Street, Filing Date: Pfizer Products Inc. New York, 21/03/2000 Warrant signed on 1430 Resorcinol composition Wef: 22/03/1999 Vide PT 1430 Attn: Lysaght & Co. New York 10017, Rec: P258899 dt 25/11/2000 United States of America 21/03/ 2000.

Eastern Point Road, Filing Date: Sorbitol dehydrogenase Pfizer Products Inc. Groton, Connecticut 21/03/2000 Warrant signed on 1431 Wef: 01/04/1999 Vide PT 1431 inhibitors Attn: Lysaght & Co. 06340, United States of Rec: P258900 dt 30/04/2001 America. 21/03/2000.

Eastern Point Road, Filing Date: Use of CYP2 D6 inhibitors in Pfizer Products Inc. Groton, Connecticut 06/04/2000 Warrant signed on 1435 Wef: 07/04/1999 Vide PT 1435 combination therapies Attn: Lysaght & Co. 06340, United States of Rec: P410159 dt 30/04/2001 America 06/04/2000

Eastern Point Road, Filing Date: Compounds for the treatment of Pfizer Products Inc. Groton, Connecticut 06/04/2000 Warrant signed on 1436 Wef: 30/04/1999 Vide PT 1436 obesity Attn: Lysaght & Co. 06340, United States of Rec: P410160 dt 30/04/2001 America 06/04/2000

Eastern Point Road, Filing Date: Glucocorticoid receptor Pfizer Products Inc. Groton, Connecticut 06/04/2000 Warrant signed on 1437 Wef: 30/04/1999 Vide PT 1437 modulators Attn: Lysaght & Co. 06340, United States of Rec: P410162 dt 30/04/2001 America 06/04/2000

Eastern Point Road, Filing Date: Substituted benzolactam Pfizer Products Inc. Groton, Connecticut 17/04/2000 Warrant signed on 1442 Wef: 06/05/1999 Vide PT 1442 compounds Attn: Lysaght & Co. 06340, United States of Rec: P410904 dt 30/04/2001 America 17/04/2000

Filing Date: Synergistic effects of amlodipine P.O. Box 585, Sewickley, R. Preston Mason 24/04/2000 Warrant signed on 1444 and atorvastatin metabolite as a PA 15143, United States Wef: 23/04/1999 Vide PT 1444 Attn: Lysaght & Co. Rec: P410203 dt 23/03/2001 basis for combination therapy of America 24/04/2000 1-TRIFLUOROMETHYL-4- Eastern Point Road, Filing Date: HYDROXY-7- Pfizer Products Inc. Groton, Connecticut 04/05/2000 Warrant signed on 1446 Wef: 21/05/1999 Vide PT 1446 PIPERIDINYlLAMINOMETHYLCHR Attn: Lysaght & Co. 06340, United States of Rec: P410233 dt 30/04/2001 OMAN DERIVATIVES America 04/05/2000

Eastern Point Road, Filing Date: Mutual salt of amlodipine and Pfizer Products Inc. Groton, Connecticut 04/05/2000 Warrant signed on 1447 wef 27/5/99. Vide PT 1447 atorvastatin Attn: Lysaght & Co. 06340, United States of Rec: P410234 dt 30/04/2001 America 04/05/2000

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, Connecticut 04/05/2000 Warrant signed on 1448 13-methyl erythromycin derivative Wef: 24/05/1999 Vide PT 1448 Attn: Lysaght & Co. 06340, United States of Rec: P410235 dt 30/04/2001 America 04/05/2000

Eastern Point Road, Filing Date: Heterocyclic derivatives useful as Pfizer Products Inc. Groton, Connecticut 05/05/2000 Warrant signed on 1449 Wef: 19/05/1999 Vide PT 1449 anticancer agents Attn: Lysaght & Co. 06340, United States of Rec: P410236 dt 30/04/2001 America 05/05/2000.

Eastern Point Road, Filing Date: 3-(arylsulfonylamino)- Pfizer Products Inc. Groton, Connecticut 05/05/2000 Warrant signed on 1450 tetrahydrofuran-3-carboxylic acid Wef: 28/05/1999 Vide PT 1450 Attn: Lysaght & Co. 06340, United States of Rec: P410237 dt 30/04/2001 hydroxamides America 05/05/2000.

Eastern Point Road, Filing Date: 3-(arylsulfonylamino)- Pfizer Products Inc. Groton, Connecticut 08/05/2000 Warrant signed on 1451 tetrahydropyran-3-carboxylic acid Wef: 28/05/1999 Vide PT 1451 Attn: Lysaght & Co. 06340, United States of Rec: P410243 dt 30/04/2001 hydroxamide America 08/05/2000

Eastern Point Road, Filing Date: Mutual prodrugs of amlodipine Pfizer Products Inc. Groton, Connecticut 11/05/2000 Warrant signed on 1453 Wef: 27/05/1999 Vide PT 1453 and atorvastatin Attn: Lysaght & Co. 06340, United States of Rec: P410272 dt 30/04/2001 America 11/05/2000

Eastern Point Road, Filing Date: New pharmaceutical Pfizer Products Inc. Groton, Connecticut 11/05/2000 Warrant signed on 1454 Wef: 21/05/1999 Vide PT 1454 combinations for NOS inhibitors Attn: Lysaght & Co. 06340, United States of Rec: P410273 dt 30/04/2001 America 11/05/2000

Polymorphs of a crystalline Eastern Point Road, Filing Date: azobicyclo (2,2,2) octan-3-amine Pfizer Products Inc. Groton, Connecticut 18/05/2000 Warrant signed on 1455 Wef: 01/06/1999 Vide PT 1455 citrate and their pharmaceutical Attn: Lysaght & Co. 06340, United States of Rec: P410302 dt 30/04/2001 compositions America 18/05/2000

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, Connecticut 18/05/2000 Warrant signed on 1456 Liprasidone Suspension Wef: 27/05/1999 Vide PT 1456 Attn: Lysaght & Co. 06340, United States of Rec: P410303 dt 29/05/2001 America 18/05/2000 Polymorphs of a crystalline azo- Eastern Point Road, Filing Date: bicyclo (2.2.2.) oct-3-yl amine Pfizer Products Inc. Groton, Connecticut 30/05/2000 Warrant signed on 1458 Wef: 01/06/1999 Vide PT 1458 citrate and their pharmaceutical Attn: Lysaght & Co. 06340, United States of Rec: P410288 dt 19/11/2001 compositions America 30/05/2000

235 East 42nd Street, Filing Date: Pfizer Inc. New York, New York 30/05/2000 Warrant signed on 1459 Mettalloprotease inhibitors Wef: 03/06/1999 Vide PT 1459 Attn: Lysaght & Co. 10017, United States of Rec: P410289 dt 30/04/2001 America 30/05/2000

Thiazole Compounds and Filing Date: Agouron Pharmaceuticals, 10350, North Torrey, pharmaceutical compositions for 31/05/2000 Warrant signed on 1460 Inc. Pines Road, La Jolle, CA Wef: 04/06/1999 Vide PT 1460 Inhibiting Protein Kinases and Rec: P410402 dt 23/03/2001 Attn: Dr. R. Frendo Randon 92037, USA Methods for their use 31/05/2000

Filing Date: 67056 Ludwigsheften, Production of polyamides from BASF Aktiengesellschaft 05/06/2000 Warrant signed on 1461 Federal Republic of Wef: 07/06/1999 Vide PT 1461 lactams and polyamide extracts Attn: S S & Co. Rec: P410416 dt 31/12/2001 Germany 05/06/2000

Filing Date: Ramsgate Road, Pfizer Limited 08/06/2000 Warrant signed on 1462 Pharmaceutical complex Sandwich, Kent CT13 Wef: 29/06/1999 Vide PT 1462 Attn: Lysaght & Co. Rec: P410293 dt 30/05/2001 9NJ, England 08/06/2000

Diphosphate salt of a 4"- Filing Date: Eastern Point Road, substituted-9-deoxo-9A-aza-9A- Pfizer Products Inc. 13/06/2000 Warrant signed on 1465 Groton, Connecticut Wef: 30/06/1999 Vide PT 1465 nomoerythrorycin derivative and Attn: Lysaght & Co. Rec: P410448 dt 27/12/2002 06340, U.S.A. its pharmaceutical composition 13/06/2000

235 East 42nd Street, Filing Date: Pfizer Inc. New York, New York 13/06/2000 Warrant signed on 1466 Purine derivatives Wef: 15/06/1999 Vide PT 1466 Attn: Lysaght & Co. 10017, United States of Rec: P410449 dt 11/12/2002 America 13/06/2000

Polymorphs of a crystalline azo- Filing Date: Eastern Point Road, bicyclo-2,2,2,oct-3-yl amine Pfizer Products Inc. 19/06/2000 Warrant signed on 1468 Groton, Connecticut Wef: 22/06/1999 Vide PT 1468 dihydrochloride and their Attn: Lysaght & Co. Rec: P410464 dt 13/10/2001 06340, U.S.A. pharmaceutical compositions 19/06/2000 Indazole compounds and Filing Date: Agouron Pharmaceuticals 10350, Novel Torrey, pharmaceutical compositions for 30/06/2000 Warrant signed on 1473 Inc. Pines Road, La Jolla, Wef: 02/07/1999 Vide PT 1473 inhibiting Protein Kinases and Rec: P410377 dt 30/04/2001 Attn: Dr. R. Frendo Randon CA 92037, USA Methods for their use 30/06/2000

Eastern Point Road, Filing Date: Process for making 5- Pfizer Products Inc. Groton, Connecticut 22/08/2000 Warrant signed on 1475 lipoxygenase inhibitors having Wef: 31/08/1999 Vide PT 1475 Attn: Lysaght & Co. 06340, United States of Rec: 185/186 dt 21/01/2003 varied heterocyclic ring systems America 22/08/2000

Filing Date: Bristol-Myers Squibb P.O Box 4000, Princeton, 23/08/2000 Warrant signed on 1476 Flash-melt oral dose formulations Company New Jersey 08543-4000, Wef: 12/04/2000 Vide PT 1476 Rec: 190/191 dt 30/04/2001 Attn: Lysaght & Co. United States of America 23/08/2000

Eastern Point Road, Filing Date: Pyrimidine-2,4,6-trione Pfizer Products Inc. Groton, Connecticut 23/08/2000 Warrant signed on 1477 Wef: 12/08/1999 Vide PT 1477 metalloprotease inhibitors Attn: Lysaght & Co. 06340, United States of Rec: 192/193 dt 14/02/2003 America 23/08/2000

Eastern Point Road, Filing Date: Process for making 5- Pfizer Products Inc. Groton, Connecticut 23/08/2000 Warrant signed on 1478 lipoxygenase inhibitors having Wef: 31/08/1999 Vide PT 1478 Attn: Lysaght & Co. 06340, United States of Rec: 194/195 dt 27/12/2002 varied heterocyclic ring systems America 23/08/2000

Filing Date: 235 East 42nd Street, Pfizer Inc. 31/08/2000 Warrant signed on 1479 Polymorphic salt New York, N.Y. 10017, Wef: 28/09/1999 Vide PT 1479 Attn: Lysaght & Co. Rec: 240/241 dt 04/09/2001 United States of America 31/08/2000

Eastern Point Road, Filing Date: Combination treatment with IL-Ira Pfizer Products Inc. Groton, Connecticut 31/08/2000 Warrant signed on 1480 and compounds that inhibit IL-1 Wef: 14/09/1999 Vide PT 1480 Attn: Lysaght & Co. 06340, United States of Rec: 243/244 dt 04/09/2001 processing and release. America 31/08/2000

35, N.E Industrial Road, Filing Date: Fused pyrrolecarboxamides; A Neurogen Corporation Branford, 31/08/2000 Warrant signed on 1481 new class of GABA Brain receptor Wef: 31/08/1999 Vide PT 1481 Att. Mr. Joseph Mifsud Connecticut 06405, Rec: 246/247 dt 04/09/2001 ligards. United States of America. 31/08/2000

Filing Date: 235 East 42nd Street, Pharmaceutically active Pfizer Inc. 19/09/2000 Warrant signed on 1484 New York, New York Wef: 11/10/1999 Vide PT 1484 compounds Attn: Lysaght & Co. Rec: 318/319 dt 04/09/2001 10017, USA 19/09/2000

Eastern Point Road, Filing Date: Compounds for the treatment of Pfizer Products Inc. Groton, Connecticut 19/09/2000 Warrant signed on 1485 Wef: 30/09/1999 Vide PT 1485 ischemia Attn: Lysaght & Co. 06340, United States of Rec: 320/321 dt 04/09/2001 America 19/09/2000 35 North East Filing Date: High affinity small molecule C5A Neurogen Corporation Industrial Road, Branford, 29/09/2000 Warrant signed on 1486 Wef: 28/09/1999 Vide PT 1486 receptor modulators. Attn: S S & Co. Connecticut 06405, Rec: 418/419 dt 27/11/2002 United States of America 29/09/2000

Filing Date: Novel biaryl ether derivatives Eastern Point Road, Pfizer Products Inc. 02/10/2000 Warrant signed on 1488 useful as Monoainine reuptake Groton, Connecticut Wef: 13/10/1999 Vide PT 1488 Attn: Lysaght & Co. Rec: 440/441 04/09/2001 inhibitors 06340, U.S.A. dt 02/10/2000

Filing Date: 235 East 42nd Street, Pfizer Inc. 02/10/2000 Warrant signed on 1489 Purine derivatives New York, New York Wef: 14/10/1999 Vide PT 1489 Attn: Lysaght & Co. Rec: 442/443 dt 04/09/2001 10017, USA 02/10/2000

Filing Date: 235 East 42nd Street, Pfizer Inc. 02/10/2000 Warrant signed on 1490 Purine derivatives New York, New York Wef: 14/10/1999 Vide PT 1490 Attn: Lysaght & Co. Rec: 444/445 dt 04/09/2001 10017, USA 02/10/2000

Process for the preparation of Filing Date: 235 East 42nd Street, pyrazolo [4-3-d] pyrimidin-7-ones- Pfizer Inc. 03/10/2000 Warrant signed on 1491 New York, New York Wef: 11/10/1999 Vide PT 1491 3-pyridylsulphonyl compounds Attn: Lysaght & Co. Rec: 448/449 dt 13/10/2001 10017, USA and intermediates thereof 03/10/2000

Filing Date: 235 East 42nd Street, Pfizer Inc. 03/10/2000 Warrant signed on 1492 Therapeutic agents New York, New York Wef : 11/10/1999 Vide PT 1492 Attn: Lysaght & Co. Rec: 450/451 dt 04/09/2001 10017, USA 03/10/2000

Filing Date: 235 East 42nd Street, Pharmaceutically active Pfizer Inc. 03/10/2000 Warrant signed on 1493 New York, New York Wef : 11/10/1999 Vide PT 1493 compounds. Attn: Lysaght & Co. Rec: 452/453 dt 04/09/2001 10017, USA 03/10/2000

Eastern Point Road, Filing Date: Sodium-hydrogen exchanger type Pfizer Products Inc. Groton, Connecticut 13/10/2000 Warrant signed on 1494 Wef: 29/10/1999 Vide PT 1494 1 inhibitor crystals Attn: Lysaght & Co. 06340, United States of Rec: 549/550 dt 13/10/2001 America 13/10/2000

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, Connecticut 13/10/2000 Warrant signed on 1495 Hygromycin derivatives Wef: 29/10/1999 Vide PT 1495 Attn: Lysaght & Co. 06340, United States of Rec: 551/552 dt 13/10/2001 America 13/10/2000

Eastern Point Road, Filing Date: Pfizer Products Inc. Groton, Connecticut 13/10/2000 Warrant signed on 1497 Hygromycin A prodrugs Wef: 29/10/1999 Vide PT 1497 Attn: Lysaght & Co. 06340, United States of Rec: 555/556 dt 13/10/2001 America 13/10/2000 Filing Date: Goelecke Salzufer 16, 30/10/2000 Warrant signed on 1499 lactam free cyclic amino acids Aktiengesellschaft D-10587 Berlin, Wef: N/A Vide PT 1499 Rec: 670/671 dt 30/05/2001 Attn: Lysaght + Co. Germany. 30/10/2000

Eastern Point Road, Filing Date: 4-Carboxyamino-2-substituted- Pfizer Products Inc. Groton, Connecticut 27/11/2000 Warrant signed on 1509 1,2,3,4-tetrahydroquinoline Wef: 30/11/1999 Vide PT 1509 Attn: Lysaght & Co. 06340, United States of Rec: 825/826 of 16/07/2003 crystal America 27/11/2000

20-Yoido-dong, Filing Date: An aqueous solution formulation LG Chemical Ltd Youngdunopo-Ku, Seoul 17/11/2000 Warrant signed on 1510 Wef: 19/11/1999 Vide PT 1510 of alpha-interferon Attn: Lysaght + Co. 130-721, Republic of Rec: 827/828 dt 06/02/2003 Korea 27/11/2000

Eastern Point Road, Filing Date: 2, 4-Diaminopyrimidine Pfizer Products Inc. Groton, Connecticut 27/11/2000 Rec: Warrant signed on 1511 compounds useful as Wef: 30/11/2000 Vide PT 1511 Attn: Lysaght & Co. 06340, United States of 829/830 dt 16/07/2003 immunosuppressants. America 27/11/2000 Eastern Point Road, Filing Date: Novel benzoimidazole derivateves Pfizer Products Inc. Groton, Connecticut 27/11/2000 Warrant signed on 1512 Wef: 30/11/1999 Vide PT 1512 useful asantiproliferative agents. Attn: Lysaght & Co. 06340, United States of Rec: 831/832 dt 26/03/2003 America 27/11/2000

Eastern Point Road, Filing Date: Pyrrolo (2,3-d) pyrimidine Pfizer Products Inc. Groton, Connecticut 06/12/2000 Warrant signed on 1516 Wef: 10/12/1999 Vide PT 1516 compounds Attn: Lysaght & Co. 06340, United States of Rec: 914/915 dt 13/10/2001 America 06/12/2000

235 East 42nd Street, Filing Date: Procollagen C-proteinase Pfizer Inc. New York, New York 06/12/2000 1517 Wef: 23/12/1999 Warrant: N/A Vide PT 1517 inhibitors Attn: Lysaght & Co. 10017, United States of Rec: 916/917 dt America 06/12/2000

201, Tabor Road, Filing Date: Treatment of neurodegenerative Warner-Lambert Company Morris Plains, New Jersey 06/12/2000 Warrant signed on 1518 Wef: 27/01/2000 Vide PT 1518 disease Attn: Lysaght & Co. 04950, United States of Rec: 920/923 dt 09/01/2002 America 06/12/2000

235 East 42nd Street, Filing Date: Composition for the treatment of Pfizer Inc. New York, New York 06/12/2000 Rec: Warrant signed on 1519 Wef: 29/12/1999 Vide PT 1519 damaged tissue Attn: Lysaght & Co. 10017, United States of 924/925 dt 13/10/2001 America 06/12/2000

Eastern Point Road, Filing Date: Hydrogen-driven layered drug Pfizer Products Inc. Groton, Connecticut 07/12/2000 Warrant signed on 1520 Wef: 23/12/1999 Vide PT 1520 dosage form Attn: Lysaght & Co. 06340, United States of Rec: 937/938 dt 19/11/2001 America 07/12/2000

Eastern Point Road, Filing Date: Pharmaceutical compositions Pfizer Products Inc. Groton, Connecticut 07/12/2000 Warrant signed on 1521 providing enhanced drug Wef: 23/12/1999 Vide PT 1521 Attn: Lysaght & Co. 06340, United States of Rec: 941/942 dt 13/10/2001 concentrations. America 07/12/2000

Filing Date: 5200, Old Orchard Road, Pharmacia Corporation 07/12/2000 Wef: 08/12/1999 Warrant signed on 1522 Valdecoxib Skokie, Illinois, Vide PT 1522 Attn: S S & Co. Rec: 943/944 dt . 15/02/2002 United States of America 07/12/2000 MT PT Patent Title Applicant Name Applicant Address MT Application Date Priority Date Status Abstract No

Anticancer compound and enantiomer seperation Eastern Point Road, Pfizer Products Inc. Filing Date: 12/12/2000 Warrant Signed on 1523 method useful for Groton, Connecticut Wef: 21/01/2000 Vide PT 1523 Attn: Lysaght & Co. Rec: 971 dt 12/12/2000 09/01/2002 synthesizing said 06340, USA compound

Novel substituted pyrazolo [4,3-e] diazepines ,pharmaceutical 201 Tabor Road, Morris Filing Date: 19/12/2000 Warner-Lambert Company Warrant signed on 1524 compositions containing Plains, New Jersey 07950, Rec: 1002/3 dt Wef: 04/01/2000 Vide PT 1524 Attn: Lysaght & Co. 31/12/2001 them, use as medicinal USA 19/12/2000 products and process for preparing them

Eastern Point Road, Filing Date: 19/12/2000 Hydrogel - driven drug Pfizer Products Inc. Warrant signed on 1525 Groton, Connecticut Rec: 1000/1 dt Wef: 23/12/1999 Vide PT 1525 dosage form Attn: Lysaght & Co. 15/02/2002 06340, USA 19/12/2000

Eastern Point Road, Hydrogel - driven drug Pfizer Products Inc. Filing Date: 19/12/2000 Warrant signed on 1526 Groton, Connecticut Wef: 28/12/1999 Vide PT 1526 dosage form Attn: Lysaght & Co. Rec: 998/9 dt 19/12/2000 15/02/2002 06340, USA

201 Tabor Road, Morris 3 - aminoquinazolin - 2,4 - Warner-Lambert Company Filing Date: 04/01/2001 Warrant signed on 1532 Plains, New Jersey 07950, Wef: 24/01/2000 Vide PT 1532 dione antibacterial agents Attn: Lysaght & Co. Rec: 41/42 dt 04/01/2001 12/01/2004 USA

Calcium dicarboxylate ethers, methods of making 201 Tabor Road, Morris Warner-Lambert Company Filing Date: 23/01/2001 Warrant signed on 1537 same & treatment of Plains, New Jersey 07950, Wef: 25/01/2000 Vide PT 1537 Attn: Lysaght & Co. Rec: 354/5 dt 23/01/2001 31/12/2001 vascular disease and USA diabetes therewith

Eastern Point Road, Conticotropin releasing Pfizer Products Inc. Filing Date 15/01/2001 Warrant signed on 1538 Groton, Connecticut Wef: 18/01/2000 Vide PT 1538 factor antagonists Attn: Lysaght + Co. Rec: 352/3 dt 23/01/2001 18/01/2002 06340, USA

201 Tabor Road, Morris Asymmetric synthesis of Warner-Lambert Company Filing Date: 23/01/2001 Warrant signed on 1539 Plains, New Jersey 07950, Wef: 27/01/2000 Vide PT 1539 pregabalin Attn: Lysaght & Co. Rec: 350/1 dt 23/01/2001 09/01/2002 USA

201 Tabor Road, Morris Filing Date: 23/01/2001 Pyrido[2,3-d] pyrimidine 2,7 - Warner-Lambert Company Warrant signed on 1540 Plains, New Jersey 07950, Rec: 348/9 dt Wef: 25/01/2000 Vide PT 1540 diamine kinase inhibitors Attn: Lysaght & Co. 09/01/2002 USA 23/01/2001 Derives amines de dihydro 1- 3, 5, - triazine et leurs LIPHA, French Nationality 34 Rue Saint-Romain, Filing Date: 26/01/2001 Warrant signed on 1542 Wef: 26/01/2000 Vide PT 1542 applications en Att: Mr J Mifsud 69008 Lyon, France Rec: 440/1 dt 26/01/2001 19/02/2003 therapeutique

Pyrimidine carboxamides Eastern Point Road, Pfizer Products Inc. Filing Date: 29/01/2001 Warrant signed on 1543 useful as inhibitors of PDE 4 Groton, Connecticut Wef: 31/01/2000 Vide PT 1543 Attn: Lysaght + Co. Rec: 443/4 of 29/01/2001 09/01/2002 isozymes 06340, USA

Nicotinamide benzofused Eastern Point Road, heterocyclyl derivatives Pfizer Products Inc. Filing Date: 29/01/2001 Warrant signed on 1544 Groton, Connecticut Wef: 31/01/2000 Vide PT 1544 useful as selective Attn: Lysaght + Co. Rec: 476/7 dt 29/01/2001 25/01/2002 06340, USA inhibitors of PDE4 isozymes

Eastern Point Road, Novel heterocyclic amide Pfizer Products Inc. Filing Date: 30/01/2001 Warrant signed on 1546 Groton, Connecticut Wef: 04/02/2000 Vide PT 1546 derivatives Attn: Lysaght + Co. Rec: 502/3 of 30/01/2001 17/06/2002 06340, USA

5-alkylpyrido [2,-3 -d] 201 Tabor Road, Morris pyrimidines as inhibitors of Warner-Lambert Company Filing Date: 12/02/2001 Warrant signed on 1548 Plains, New Jersey 07950, Wef: 06/08/2000 Vide PT 1548 cyclin dependent and Attn: Lysaght & Co. Rec: 667/8 dt 12/02/2001 17/06/2002 USA tyrosine kinases

Eastern Point Road, Pfizer Products Inc. Filing Date: 12/02/2001 Warrant signed on 1549 Purine derivatives Groton, Connecticut Wef : 18/02/2000 Vide PT 1549 Attn: Lysaght + Co. Rec: 665/6 dt 12/02/2001 27/01/2004 06340, USA

Process for the simple preparation of [3- chloro - 4 - fluorophenyl] - [7-(3- morpholin 4-yl-propoxy) -6- GÖDECKE GMBH Salzufer 16, 10587 Berlin, Filing Date: 26/02/2001 Warrant signed on 1552 nitroquinazolin -4yl] aime or Wef: 26/02/2000 Vide PT 1552 Attn: Lysaght & Co. Germany Rec: 862/3 dt 26/02/2001 24/05/2002 (3-chloro-4-fluorophenyl) - [7- (3- morpholin -4-yl- propoxy) -6- aminoquinazolin 4-yl] amine

New Salt Form & Pfizer Inc. 235 East 42nd Street, Filing Date: 26/02/2001 Warrant signed on 1553 Wef: 03/03/2000 Vide PT 1553 Polymorphs Att: Lysaght & Co. New York 10017, USA Rec: 864/5 dt 26/02/2001 27/02/2004

Pyrazole ether derivatives as Eastern Point Road, Pfizer Products Inc. Filing Date: 02/03/2001 Warrant signed on 1555 anti-inflamatory / analgesic Groton, Connecticut Wef: 03/03/2000 Vide PT 1555 Attn: Lysaght + Co. Rec 924/5 dt 02/03/2001 27/02/2004 agents 06340, USA

Eastern Point Road, Sodium-hydrogen Pfizer Products Inc. Filing Date: 05/03/2001 Warrant signed on 1556 Groton, Connecticut Wef: 28/04/2000 Vide PT 1556 exchanger type 1 inhibitor Attn: Lysaght + Co. Rec: 993/4 dt 05/03/2001 24/05/2002 06340, USA Eastern Point Road, Diphenyl ether compunds Pfizer Products Inc. Filing Date: 05/03/2001 Warrant signed on 1557 Groton, Connecticut Wef: 31/03/2000 Vide PT 1557 useful in therapy Attn: Lysaght + Co. Rec: 995/6 dt 05/03/2001 10/05/2002 06340, USA

Pharmaceutical Eastern Point Road, Pfizer Products Inc. Filing Date: 05/03/2001 Warrant signed on 1558 compositions of glycogen Groton, Connecticut Wef: 16/02/2000 Vide PT 1558 Attn: Lysaght + Co. Rec: 997/8 dt 05/03/2001 10/05/2002 phosphorylase inhibitors 06340, USA

Filing Date: 06/03/2001 Medicament for the NOWICKY WASSYL Margaretenstrasse 7, A- Warrant signed on 1559 Rec: 1013/4 dt Wef: 23/03/2000 Vide PT 1559 treatment of hepatitis C Attn: S S & Co. 1040 Vienna, Austria 18/01/2002 06/03/2001

Eastern Point Road, Filing Date: 12/03/2001 Glycogen phosphorylase Pfizer Products Inc. Warrant signed on 1560 Groton, Connecticut Rec: 1147/8 dt Wef: 16/03/2000 Vide PT 1560 inhibitor Attn: Lysaght + Co. 10/05/2002 06340, USA 12/03/2001

Malonamic acids & Eastern Point Road, Filing Date: 20/03/2001 Pfizer Products Inc. Warrant signed on 1561 derivatives thereof as Groton, Connecticut Rec: 1212/3 dt wef 31/03/2000 Vide PT 1561 Attn: Lysaght + Co. 24/05/2002 thyroid receptor ligands 06340, USA 20/03/2001

Eastern Point Road, Filing Date: 22/03/2001 Pfizer Products Inc. Warrant signed on 1565 Novel Piperazine derivatives Groton, Connecticut Rec: 1269/70 dt Wef: 31/03/2000 Vide PT 1565 Attn: Lysaght + Co. 27/02/2004 06340, USA 22/03/2001

Eastern Point Road, Filing Date: 02/04/2001 Estrogen agonist / Pfizer Products Inc. Warrant signed on 1567 Groton, Connecticut Rec: 1416/7 dt Wef: 07/04/2000 Vide PT 1567 antagonist metabolites Attn: Lysaght + Co. 17/06/2002 06340, USA 02/04/2001

A pharmaceutical composition for treatment of Eastern Point Road, Filing Date: 02/04/2001 Pfizer Products Inc. Warrant signed on 1568 acute, chronic pain and/or Groton, Connecticut Rec: 1414/5 dt Wef: 07/04/2000 Vide PT 1568 Attn: Lysaght + Co. 24/05/2002 neuropathic pain and 06340, USA 02/04/2001 migraines

201 Tabor Road, Morris Filing Date: 02/04/2001 Antihypertensive agents Warner-Lambert Company Warrant signed on 1569 Plains, New Jersey 07950, Rec: 1412/3 dt Wef: 26/04/2000 Vide PT 1569 and use Attn: Lysaght + Co. 25/01/2002 USA 02/04/2001

Process for the preparation of 6-(4-chlorophenyl)-2, 2- Filing Date: 06/04/2001 Merckle GmbH Graf-Arco Street 3, 89079 Warrant signed on 1570 dimethy -7- phenyl -2, 3- Rec: 1504/5 dt Wef: N/A Vide PT 1570 Attn: MAMO TCV Advocates Ulm, Germany 25/01/2002 dihydro -14- pyrolizin -5- 06/04/2001 ylacetic acid

Benzamide piperidine Eastern Point Road, Filing Date: 10/04/2001 Pfizer Products Inc. Warrant signed on 1571 containing compounds and Groton, Connecticut Rec: 1547/8 dt Wef: 10/04/2000 Vide PT 1571 Attn: Lysaght + Co. 27/02/2004 related compounds 06340, USA 01/04/2001 201 Tabor Road, Morris Filing Date: 26/04/2001 Carboxyalkylether - ACAT Warner-Lambert Company Warrant signed on 1573 Plains, New Jersey 07950, Rec: 1720/1 dt Wef: 07/06/2000 Vide PT 1573 inhibitor combinations Attn: Lysaght + Co. 27/08/2002 USA 26/04/2001

A pharmaceutical composition and method of Eastern Point Road, Filing Date: 10/05/2001 Pfizer Products Inc. Warrant signed on 1574 treatment of diseases of Groton, Connecticut Rec: 1844/5 dt Wef: 09/05/2000 Vide PT 1574 Attn: Lysaght + Co. 30/12/2002 cognitive dysfunstion in a 06340, USA 10/05/2001 mammal

Combination of growth Eastern Point Road, Filing Date: 24/05/2001 Pfizer Products Inc. Warrant signed on 1576 hormone secretagogues Groton, Connecticut Rec: 2033/4 dt Wef: 25/05/2000 Vide PT 1576 Attn: Lysaght + Co. 10/05/2002 and antidepressents 06340, USA 24/05/2001

Reactive crystallization Eastern Point Road, Filing Date: 25/05/2001 Pfizer Products Inc. Warrant signed on 1577 method to improve particle Groton, Connecticut Rec: 2066/7 dt Wef: 26/05/2000 Vide PT 1577 Attn: Lysaght + Co. 10/05/2002 size 06340, USA 25/05/2001

Filing Date: 25/05/2001 Tropane derivatives useful Pfizer Inc. 235 East 42nd Street, Warrant signed on 1578 Rec: 2068/9 dt Wef: 26/05/2000 Vide PT 1578 in therapy Attn: Lysaght + Co. New York 10017, USA 24/05/2002 25/05/2001

Eastern Point Road, Filing Date: 31/05/2001 Pfizer Products Inc. Warrant signed on 1579 Hygromycin A derivatives Groton, Connecticut Rec: 2128/9 dt Wef: 02/06/2000 Vide PT 1579 Attn: Lysaght + Co. 10/05/2002 06340, USA 31/05/2001

2 - aminocor bonyl - 94 - Pfizer Inc. 235 East 42nd Street, Filing Date: 31/05/2001 Warrant signed on 1580 Wef: 06/06/2000 Vide PT 1580 purine derivatives Attn: Lysaght + Co. New York 10017, USA Rec: 2126 dt 31/05/2001 27/08/2002

Eastern Point Road, Filing Date: 31/05/2001 Thiophene derivatives Pfizer Products Inc. Warrant signed on 1581 Groton, Connecticut Rec: 2124/5 dt Wef: 06/06/2000 Vide PT 1581 useful as anticancer agents Attn: Lysaght + Co. 24/05/2002 06340, USA 31/05/2001

S - methyl - dihydro - Eastern Point Road, Fiing Date: 31/05/2001 siprasidone for treatment of Pfizer Products Inc. Warrant signed on 1582 Groton, Connecticut Rec: 2122/3 dt Wef: 02/06/2000 Vide PT 1582 psychiatric and ocular Attn: Lysaght + Co. 24/05/2002 06340, USA 31/05/2001 disorders

Novel process for the 235 East 42nd Street, Filing Date: 13/06/2001 Pfizer Inc. Warrant signed on 1584 preparation of New York, New York Rec: 2253/4 dt Wef: 22/06/2000 Vide PT 1584 Att: Lysaght + Co. 24/05/2002 pyrazolopyrimidinones 10017, USA 13/06/2001

Eastern Point Road, Filing Date: 21/06/2001 Pyrolo [2.3-d] pyrimidine Pfizer Products Inc. Warrant signed on 1585 Groton, Connecticut Rec: 2355/6 dt W:ef 26/06/2000 Vide PT 1585 compounds Attn: Lysaght + Co. 10/05/2002 06340, USA 21/06/2001

Substituted bicyclic Eastern Point Road, Filing Date: 21/06/2001 Pfizer Products Inc. Warrant signed on 1586 derivatives for the treatment Groton, Connecticut Rec: 2353/4 dt Wef: 22/06/2000 Vide PT 1586 Attn: Lysaght + Co. 24/05/2002 of abnormal cell growth 06340, USA 21/06/2001 235 East 42nd Street, Filing Date: 21/06/2001 Pfizer Inc. Warrant signed on 1587 Purine derivatives New York, New York Rec: 2351/2 dt wef 27/06/2000 Vide PT 1587 Att: Lysaght + Co. 24/05/2002 10017, USA 21/06/2001

Novel process for the Filing Date: 21/06/2001 Pfizer Inc. 235 East 42nd Street, Warrant signed on 1588 preparation of Rec: 2349/50 dt Wef: 22/06/2000 Vide PT 1588 Attn: Lysaght & Co. New York 10017, USA 24/05/2002 pyrazolopyrimidiones 21/06/2001

Eastern Point Road, Filing Date: 21/06/2001 Melanocortin receptor Pfizer Products Inc. Warrant Signed on 1589 Groton, Connecticut Rec: 2347/8 dt Wef: 28/06/2000 Vide PT 1589 ligands Attn: Lysaght + Co. 21/08/2002 06340, USA 21/06/2001

67056 Ludwigstrafen, Filing Date: 26/06/2001 Basf Aktingesellschaft Warrant signed on 1591 Polyamides Federal Republic of Rec: 2416/2429 dt Wef: 28/06/2000 Vide PT 1591 Att: S S & Co. 18/01/2002 Germany 26/06/2001

67056 Ludwigstrafen, Filing Date: 26/06/2001 Basf Aktingesellschaft Warrant signed on 1592 Polyamides Federal Republic of Rec: 2416/2429 dt Wef: 28/06/2000 Vide PT 1592 Att: S S & Co. 18/01/2002 Germany 26/06/2001

Polymorphic forms/ hydrates of N-[4-(3-chloro-4- Filing Date: 26/06/2001 fluoro - phenylamino) -7-(3- GÖDECKE GMBH Pfizerstrasse 1, 76139 Warrant signed on 1593 Rec: 2430/1 dt Wef: 30/06/2000 Vide PT 1593 morpholin -4- yl propoxy) - Att: Dr A. Sammut Karlsruhe, Germany 21/01/2004 26/06/2001 quinazolin -6-4 l ]- acrylamide

Benozophenones and Eastern Point Road, Filing Date: 27/06/2001 Pfizer Products Inc. Warrant signed on 1594 sulfones as inhibitors of Groton, Connecticut Rec: 2442/3 dt Wef: 30/06/2000 Vide PT 1594 Attn: Lysaght + Co. 24/05/2002 glycine uptake 06340, USA 27/06/2001

Oxygenated esters of 4- 201 Tabor Road, Morris Filing Date: 02/07/2001 Warner-Lambert Company Warrant signed on 1597 iodo phenylamino Plains, New Jersey 07950, Rec: 2488/9 dt Wef: 19/07/2000 Vide PT 1597 Attn: Lysaght + Co. 27/02/2004 benzhydroxamic acids USA 02/07/2001

Cyclopentyl - substituted 235 East 42nd Street, Filing Date: 02/07/2001 glutaramide derivatives as Pfizer Inc. Warrant signed on 1598 New York, New York Rec: 2486/7 dt Wef: 06/07/2000 Vide PT 1598 inhibitors of neutral Att: Lysaght + Co. 21/08/2002 10017, USA 02/07/2001 endopeptidase

235 East 42nd Street, Filing Date: 02/07/2001 Pfizer Inc. Warrant signed on 1599 Pyrazole derivatives New York, New York Rec: 2484/5 dt Wef: 07/07/2000 Vide PT 1599 Att: Lysaght + Co. 27/08/2002 10017, USA 02/07/2001

Treatment of polyamide with 3000 Continental Drive, Filing Date: 09/07/2001 BASF Corporation Warrant signed on 1603 gas phase of acid anyhdride Hosel, Mount Clive, New Rec: 2598/9 dt Wef: 10/07/2000 Vide PT 1603 Att: S S & Co 27/08/2002 or amino Jersey 07828 - 1234, USA 11/07/2001 67056 Ludwigstrafen, Filing Date: 11/07/2001 Continuous preparation of BASF Aktiengesellschaft Warrant signed on 1604 Federal Republic of Rec: 2663/4 dt Wef: 11/07/2000 Vide PT 1604 polyamides from aminotiles Att: S S & Co 24/05/2002 Germany 16/07/2001

Process for preparing 2-(4- 201 Tabor Road, Morris Filing Date: 18/07/2001 pyridyl) amino -6- Warner-Lambert Company Warrant signed on 1605 Plains, New Jersey 07950, Rec: 2680/1 dt Wef: 04/08/2000 Vide PT 1605 dialkyloxophenyl - pyrido Attn: Lysaght + Co. 21/08/2002 USA 18/07/2001 [2,3-d]

235 East 42nd Street, Filing Date: 18/07/2001 Crystalline therapeutic Pfizer Inc. Warrant signed on 1606 New York, New York Rec: 2682/3 dt Wef: 08/07/2000 Vide PT 1606 agent Att: Lysaght + Co. 27/08/2002 10017, USA 18/07/2001

2-(4-pyridy) amino -6- 201 Tabor Road, Morris Filing Date: 18/07/2001 Warner-Lambert Company Warrant signed on 1607 dialkoxyphenyl - pyrido [2,3- Plains, New Jersey 07950, Rec: 2684/5 dt Wef: 04/08/2000 Vide PT 1607 Attn: Lysaght + Co. 21/08/2002 d] pyrimidin -7- ones USA 18/07/2001

Filing Date: 18/07/2001 Particulate composition of Pfizer Inc. 235 East 42nd Street, Warrant signed on 1608 Rec: 2686/7 dt Wef: 02/08/2000 Vide PT 1608 eletiptan Att: Lysaght + Co. New York 10017, USA 27/11/2002 18/07/2001

Process for making N-aryl- 201 Tabor Road, Morris Filing Date: 27/07/2001 Warner-Lambert Company Warrant signed on 1609 anthranilic acids and their Plains, New Jersey 07950, Rec: 2808/9 dt Wef: 25/08/2000 Vide PT 1609 Attn: Lysaght + Co. 04/11/2002 derivatives antharanilic USA 27/07/2001

Eastern Point Road, Filing Date: 27/07/2001 Pfizer Products Inc Warrant signed on 1610 Imidozole derivatives Groton, Connecticut Rec: 2806/7 dt wef 31/07/2000 Vide PT 1610 Attn: Lysaght + Co. 21/08/2002 06340, USA 27/07/2001

Filing Date: 27/07/2001 Phenoxybenzylamine Pfizer Inc. 235 East 42nd Street, Warrat signed on 1611 Rec: 2804/5 dt Wef: 31/08/2000 Vide PT 1611 derivatives as SSRIs Att: Lysaght + Co. New York 10017, USA 27/08/2002 27/07/2001

Pharmaceutical Eastern Point Road, Filing Date: 02/08/2001 compositions of cholesteryl Pfizer Products Inc Warrant signed on 1613 Groton, Connecticut Rec: 2901/2 dt Wef: 03/08/2000 Vide PT 1613 ester transfer protein Attn: Lysaght + Co. 27/08/2002 06340, USA 02/08/2001 inhibitors

67056 Ludwigstraben, Filing Date: 02/08/2001 Preparation of lipoic and BASF Aktiengesellschaft Warrant signed on 1614 Federal Republic of Rec: 2899/2990 Wef: 02/08/2001 Vide PT 1614 dihydrolipoic Att: S S & Co. 31/05/2002 Germany dt 02/08/2001

Novel 1,4- dihydropyridine Filing Date: 02/08/2001 Pfizer Inc. 235 East 42nd Street, Warrant signed on 1615 compounds as bradykinin Rec: 2897/8 dt Wef: 10/08/2000 Vide PT 1615 Att: Lysaght + Co. New York 10017, USA 21/08/2002 antagonists 02/08/2001

Filing Date: 02/08/2001 Pfizer Inc. 235 East 42nd Street, Warrant signed on 1616 Pharmaceuticals Rec: 2895/6 dt Wef: 17/08/2000 Vide PT 1616 Att: Lysaght + Co. New York 10017, USA 21/08/2002 02/08/2001 Eastern Point Road, Filing Date: 02/08/2001 Pfizer Products Inc Warrant signed on 1617 Therapeutic combination Groton, Connecticut Rec: 2893/4 dt Wef: 15/08/2000 Vide PT 1617 Attn: Lysaght + Co. 27/08/2002 06340, USA 02/08/2001

Eastern Point Road, Filing Date: 02/08/2001 Pfizer Products Inc Warrant signed on 1618 Macrolide antibiotics Groton, Connecticut Rec: 2891/2 dt Wef: 07/08/2000 Vide PT 1618 Attn: Lysaght + Co. 27/08/2002 06340, USA 02/08/2001

35 NE Industrial Road, Filing Date: 07/08/2001 Neurogen Corporation Warrant signed on 1620 Substituted Arylpyrazines Branford, Connecticut Rec: 2930/1 dt Wef: N/A Vide PT 1620 Attn: Mr J. Mifsud 03/02/2004 06405, USA 07/08/2001

Eastern Point Road, Filing Date: 09/08/2001 Hydrogel - driven drug Pfizer Products Inc Warrant signed on 1622 Groton, Connecticut Rec: 2966/7 dt Wef: 09/08/2000 Vide PT 1622 dosage form Attn: Lysaght + Co. 21/08/2002 06340, USA 10/08/2001

Eastern Point Road, Groton, Connecticut Pfizer Products Inc. & Comas Filing Date: 17/08/2001 Process the preparation of 06340, USA & 3030 Warrant signed on 1623 International Inc. Rec: 3018/9 dt Wef: 23/08/2000 Vide PT 1623 Neutrophil inhibitory factor Science Park Road, San 24/05/2002 Att: S S & Co 17/08/2001 Diego, California 92121, USA

Eastern Point Road, Filing Date: 20/08/2001 Pfizer Products Inc Warrant signed on 1624 Pyrazole derivatives Groton, Connecticut Rec: 3042/3 dt Wef: 31/08/2000 Vide PT 1624 Attn: Lysaght + Co. 27/08/2002 06340, USA 20/08/2001

Sustained release Eastern Point Road, Filing Date: 20/08/2001 Pfizer Products Inc Warrant signed on 1625 formulations for growth Groton, Connecticut Rec: 3040/1 dt Wef: 30/08/2000 Vide PT 1625 Attn: Lysaght + Co. 27/08/2002 hormone secretagogues 06340, USA 20/08/2001

Filing Date: 27/08/2001 Pfizer Inc. 235 East 42nd Street, Warrant signed on 1626 Purine deivatives Rec: 3127/88 dt Wef: 15/09/2000 Vide PT 1626 Att: Lysaght + Co. New York 10017, USA 21/08/2002 27/08/2001

Branched chain amino acid dependent 201 Tabor Road, Morris Filing Date: 04/09/2001 aminotransferase inhibitors Warner-Lambert Company Warrant signed on 1628 Plains, New Jersey 07950, Rec: 3207/8 dt Wef: 19/09/2000 Vide PT 1628 and their use in the Att: S S &Co. 24/05/2002 USA 04/09/2001 treatment of neurodegenerative diseases

New thiadiazoles and 201 Tabor Road, Morris Filing Date: 25/09/2001 oxadiazoles and their use as Warner-Lambert Company Warrant signed on 1641 Plains, New Jersey 07950, Rec: 3406/7 dt Wef: 02/10/200 Vide PT 1641 phosphodiesterase -7 Att: Lysaght + Co. 27/11/2002 USA 25/09/2001 inhibitors (7- [3-Carboxyphenyl] -4- Filing Date: 27/09/2001 Pfizer Inc. 235 East 42nd Street, Warrant Signed on 1642 chloroisoquinolin -1-yl) Rec: 3437/8 dt Wef: 30/10/2000 Vide PT 1642 Att: Lysaght + Co. New York 10017, USA 27/11/2002 guanidine 27/09/2001

Filing Date: 27/09/2001 Pharmaceutical Pfizer Inc. 235 East 42nd Street, Warrant signed on 1643 Rec: 3435/6 dt Wef: 17/10/2000 Vide PT 1643 combinations Att: Lysaght + Co. New York 10017, USA 26/02/2003 27/09/2001

Aryl or heteroaryl fused Filing Date: 08/10/2001 imidazole compounds as Pfizer Inc. 235 East 42nd Street, Warrant signed on 1646 Rec: 3558/9 dt Wef: 19/10/2000 Vide PT 1646 anti-inflammatory and Att: Lysaght + Co. New York 10017, USA 31/12/2002 08/10/2001 analgesic agents

Eastern Point Road, Filing Date: 08/10/2001 Bridged piperazine Pfizer Products Inc Warrant signed on 1647 Groton, Connecticut Rec: 3556/7 dt Wef: 19/10/2000 Vide PT 1647 derivatives Att: Lysaght + Co. 27/11/2002 06340, USA 08/10/2001

Sipro-pyrimidine - 2,4,6- Eastern Point Road, Filing Date: 15/10/2001 Pfizer Products Inc Warrant signed on 1648 trione metalloproteinase Groton, Connecticut Rec: 3632/3 dt Wef: 26/10/2000 Vide PT 1648 Att: Lysaght + Co. 26/02/2003 inhibitors 06340, USA 15/10/2001

Eastern Point Road, Filing Date: 15/10/2001 Pyrimidine - 2,4,6-trione Pfizer Products Inc Warrant signed on 1649 Groton, Connecticut Rec: 3630/1 dt Wef: 26/10/2001 Vide PT 1649 metalloproteinase inhibitors Att: Lysaght + Co. 27/11/2002 06340, USA 15/10/2001

Eastern Point Road, Filing Date: 15/10/2001 B3 Adrenergic receptor Pfizer Products Inc Warrant signed on 1650 Groton, Connecticut Rec: 3628/9 dt Wef: 20/10/2001 Vide PT 1650 agonists and uses thereof Att: Lysaght + Co. 19/02/2003 06340, USA 15/10/2001

Filing Date: 24/10/2001 Process for the preparation Zambon Group Spa Via della Chimica 9, I / Warrant signed on 1651 Rec: 3745/6 dt Wef: 23/10/2001 Vide PT 1651 of Gabapentin Attn: S S & Co. 36100 Vicenza, Italy 10/05/2002 24/10/2001

Combination of gaba Eastern Point Road, Filing Date: 06/11/2001 Pfizer Products Inc Warrant signed on 1653 agonists and sorbitol Groton, Connecticut Rec: 3883/4 dt Wef: 30/11/2000 Vide PT 1653 Att: Lysaght + Co. 26/02/2003 dehydrogenase inhibitors 06340, USA 06/11/2001

EP4 Receptor selective Eastern Point Road, Filing Date: 19/11/2001 Pfizer Products Inc Warrant signed on 1654 agonists in the treatment of Groton, Connecticut Rec: 4043/4 dt Wef: 27/11/2000 Vide PT 1654 Att: Lysaght + Co. 26/02/2003 osteoporosis 06340, USA 19/11/2001

Combination of gaba Eastern Point Road, Filing Date: 19/11/2001 Pfizer Products Inc Warrant signed on 1655 agonists and aldose Groton, Connecticut Rec: 4041/2 dt Wef: 30/11/2000 Vide PT 1655 Att: Lysaght + Co. 14/02/2003 reductase inhibitors 06340, USA 19/11/2001

Piperidine derivatives as 201 Tabor Road, Morris Filing Date: 19/11/2001 Warner-Lambert Company Warrant signed on 1656 subtype selective n-methyl- Plains, New Jersey 07950, Rec: 4039/40 dt Wef: 21/12/2000 Vide PT 1656 Att: Lysaght + Co. 29/08/2003 d-aspartate antagonists USA 19/11/2001 Salt forms of 3-(4-bromo-2 , 6-difluoro-benzyloxy) -5- [3- Eastern Point Road, Filing Date: 19/11/2001 (4-pyrrolidin -1-yl- butyl) Pfizer Products Inc Warrant signed on 1657 Groton, Connecticut Rec: 4037/8 dt Wef: 28/11/2000 Vide PT 1657 uriedo] - isothiazole -4- Att: Lysaght + Co. 26/02/2003 06340, USA 19/11/2001 carboxylic acid amide and method of production

67056 Ludwigstraben, Filing Date: 26/11/2001 BASF Aktiengesellschaft Warrant signed on 1658 Polyamide Federal Republic of Rec: 4109/4110 dt Wef: 23/11/2000 Vide PT 1658 Att: S S & Co. 27/08/2002 Germany 26/11/2001

67056 Ludwigstraben, Filing Date: 26/11/2001 BASF Aktiengesellschaft Warrant signed on 1659 Multicomponent fiber Federal Republic of Rec: 4111/2 dt Wef: 23/11/2000 Vide PT 1659 Att: S S & Co. 03/03/2004 Germany 26/11/2001

3-Ox(adi) azolylpropanohydroxamic Filing Date: 28/11/2001 Pfizer Inc. 235 East 42nd Street, Warrant signed on 1660 acids useful acids as Rec: 4131/2 dt Wef: 01/12/2000 Vide PT 1660 Att: Lysaght + Co. New York 10017, USA 13/03/2003 procollagen C-proteinase 28/11/2001 inhibitors

NMDA receptor agonist Eastern Point Road, Filing Date: 28/11/2001 Pfizer Products Inc Warrant signed on 1661 pharmaceutical Groton, Connecticut Rec: 4129/30 dt Wef: 13/12/2000 Vide PT 1661 Att: Lysaght + Co. 06/02/2003 compositions 06340, USA 28/11/2001

235 East 42nd Street, New York 10017, USA Filing Date: 21/12/2001 Antibodies to Insulin-like Pfizer Inc. & Abgenix Inc. Warrant signed on 1662 & 7601 Dumbarton Circle, Rec: 4365/6 dt Wef: 05/01/2001 Vide PT 1662 growth factor I receptor Att: S S & Co. 27/11/2002 Fremont, California 21/12/2001 94555, USA

Benzinidazole and 35 NE Industrial Road, Filing Date: 20/12/2001 Phyridylimidazole Newrogen Corporation Warrant signed on 1663 Branford, Connecticut Rec: 4367/8 dt Wef: 21/12/2000 Vide PT 1663 derivatives as ligands for Attn: 27/02/2004 06405, USA 20/12/2001 GabaA receptors

histamine receptor Pfizer Inc. 235 East 42nd Street, Filing Date: 01/01/2002 Warrant signed on 1664 Wef: 17/01/2001 Vide PT 1664 antagonists Att: Lysaght + Co. New York 10017, USA Rec: 30/31 dt 02/01/2002 21/08/2002

Eastern Point Road, Ether derivatives useful as Pfizer Products Inc Filing Date: 01/01/2002 Warrant signed on 1665 Groton, Connecticut Wef: 31/01/2001 Vide PT 1665 inhibitors of PDE4 isozymes Att: Lysaght + Co. Rec: 32/33 dt 02/01/2002 29/08/2003 06340, USA

201 Tabor Road, Morris Filing Date: 17/01/2002 Benzo thiadiazine matrix Warner-Lambert Company Warrant signed on 1669 Plains, New Jersey 07950, Rec: 194/195 dt Wef: 14/02/2001 Vide PT 1669 metalloproteinase inhibitors Att: S S & Co. 21/08/2002 USA 17/01/2002 Eastern Point Road, Filing date 23/01/2002 Pfizer Products Inc Warrant signed on 1671 Ppar agonists Groton, Connecticut Rec: 238/9 Wef: 15/02/2001 Vide PT 1671 Att: Lysaght + Co. 29/08/2003 06340, USA dt 30/01/2002

Eastern Point Road, Filing date 23/01/2002 Pfizer Products Inc Warrant signed on 1672 Ppar compounds Groton, Connecticut Rec: 240/1 Wef: 15/02/2001 Vide PT 1672 Att: Lysaght + Co. 29/08/2003 06340, USA dt 30/01/2002

201 Tabor Road, Morris Filing date: 28/01/2002 Fused pyrimidine matrix Warner-Lambert Company Warrant signed on 1673 Plains, New Jersey 07950, Rec: 242/243 Wef: 14/02/2001 Vide PT 1673 metalloproteinase inhibitors Att: S S & Co. 29/08/2003 USA dt 30/01/2002

201 Tabor Road, Morris Filing Date: 31/01/2002 Quinazolines as MMP - 13 Warner-Lambert Company Warrant signed on 1676 Plains, New Jersey 07950, Rec: 353/354 dt Wef: 14/02/2001 Vide PT 1676 inhibitors Att: Lysaght & Co. 29/08/2003 USA 01/02/2002

201 Tabor Road, Morris Filing Date: 31/01/2002 Pyrimidine matrix Warner-Lambert Company Warrant signed on 1677 Plains, New Jersey 07950, Rec: 351/352 Wef: 14/02/2001 Vide PT 1677 metalloproteinase inhibitors Att: Lysaght & Co. 29/08/2003 USA dt 01/02/2002

201 Tabor Road, Morris Filing date: 31/01/2002 Triazolo compounds as Warner-Lambert Company Warrant signed on 1678 Plains, New Jersey 07950, Rec: 349/350 dt Wef: 14/02/2001 Vide PT 1678 MMP inhibitors Att: Lysaght & Co. 29/08/2003 USA 01/02/2002

201 Tabor Road, Morris Filing date: 31/01/2002 Pyridine matrix Warner-Lambert Company Warrant signed on 1679 Plains, New Jersey 07950, Rec: 347/348 dt Wef: 14/02/2001 Vide PT 1679 metalloproteinase inhibitors Att: Lysaght & Co. 03/11/2003 USA 01/02/2002

Isophathalic acid derivatives 201 Tabor Road, Morris Filing date: 31/01/2002 Warner-Lambert Company Warrant signed on 1680 as matrix metalloproteinase Plains, New Jersey 07950, Rec: 345/346 dt Wef: 14/02/2001 Vide PT 1680 Att: Lysaght & Co. 03/11/2003 inhibitors USA 01/02/2002

201 Tabor Road, Morris Filing date: 31/01/2002 Bicyclic pyrimidine matrix Warner-Lambert Company Warrant signed on 1681 Plains, New Jersey 07950, Rec: 343/344 dt Wef: 14/02/2001 Vide PT 1681 metalloproteinase inhibitors Att: Lysaght & Co. 03/11/2003 USA 01/02/2002

201 Tabor Road, Morris Filing Date: 08/02/2002 Matrix metalloproteinase Warner-Lambert Company Warrant signed on 1682 Plains, New Jersey 07950, Rec: 488/9 Wef: 14/02/2001 Vide PT 1682 inhibitors Att: Lysaght & Co. 13/03/2003 USA dt 08/02/2002 Use of GABA inverse agonists in combination with nicotine receptor Eastern Point Road, Filing date: 08/02/2002 partial agonists estrogen, Pfizer Products Inc Warrant signed on 1683 Groton, Connecticut Rec: 499/500 dt Wef: 01/03/2001 Vide PT 1683 selective estrogen Att: Lysaght + Co. 01/08/2003 06340, USA 08/12/2002 modulators or vitamin E for the treatment of cognitive disorders

Eastern Point Road, Filing date: 08/02/2002 Novel benzimidazole anti- Pfizer Products Inc Warrant signed on 1684 Groton, Connecticut Rec: 497/498 dt Wef: 09/03/2001 Vide PT 1684 inflammatory compounds Att: Lysaght + Co. 03/11/2003 06340, USA 08/02/2002

3-heterocyclyl Filing date: 21/02/2002 Pfizer Inc. 235 East 42nd Street, Warrat signed on 1686 propanohydroxamic acid Rec: 639/640 dt Wef: 30/03/2001 Vide PT 1686 Att: Lysaght + Co. New York 10017, USA 29/08/2003 PCP inhibitors 21/02/2002

Eastern Point Road, Filign date: 21/02/2002 Pyridazinone aldose Pfizer Products Inc Warrant signed on 1687 Groton, Connecticut Rec: 637/638 W:ef 30/03/2001 Vide PT 1687 reductase inhibitors Att: Lysaght + Co. 29/08/2003 06340, USA dt 21/02/2002 MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Filing Date: 21/02/2002 Novel Triazolo - Pyridines Anti- Pfizer Products Inc Eastern Point Road, Groton, Rec 635+636 dt Warrant signed on 1688 Wef: 09/03/2001 Vide PT 1688 inflammatory Compounds Attn: Lysaght & Co. Connecticut 06340, USA 21/02/2002 29/08/2003

235 East 42nd Street, New York, Filing Date: 21/02/2002 Pharmaceutically Active Pfizer Inc Wef: 09/03/2001 1689 NY 10017, United States of Rec 633+634 dt WITHDRAWN Vide PT 1689 Compounds Attn: Lysaght & Co. America 21/02/2002

235 East 42nd Street, New York, Filing date: 25/02/2002 3-heterocyclylpropanohydroxamic Pfizer Inc Warrant signed on 1690 NY 10017, United States of Rec 696+ 697 dt Wef: 30/03/2001 Vide PT 1690 Acid PCP Inhibitors Attn: Lysaght & Co. 08/10/2003 America 26/02/2002

Filing date: 13/03/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1693 Pregabalin Lactose Conjugates Rec 837+ 838 dt Wef: 30/03/2001 Vide PT 1693 Attn: Lysaght & Co New Jersey 07950, USA 29/08/2003 13/03/2002

N-phenpropylcyclopentyl - 235 East 42nd Street, New York, Filing date: 13/03/2002 Substituted Glutaramide Pfizer Inc Warrant signed on 1694 NY 10017, United States of Rec 835+ 836 dt Wef: 28/03/200 Vide PT 1694 Derivatives as NEP Inhibtiors for Attn: Lysaght & Co. 30/09/2003 America 13/03/2002 FSAD

New Spirotricyclic Derivatives and Filing date: 13/03/2002 Warner-Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1695 their Use as Phosphodiesterase-7 Rec 833+ 834 dt Wef: 21/03/2001 Vide PT 1695 Attn: Lysaght & Co New Jersey 07950, USA 02/09/2003 Inhibitors 13/03/2002

235 East 42nd Street, New York, Filing date: 15/03/2002 Pfizer Inc Warrant signed on 1697 Pyrazole Derivatives NY 10017, United States of Rec 906+907 dt Wef: 10/04/2001 Vide PT 1697 Attn: Lysaght & Co. 01/09/2003 America 15/03/2002

Wef: 23/03/2001 A German company of 67056 Filing date: 18/03/2002 5th Annuity due on BASF Alstiengesellsdiaft Warrant Signed on 1698 Preparation of Polyamides Ludwigshafen Rec 933 + 934 dt 18/03/2006 Vide PT 1698 Att: Salamone, Sansone & Co. 06/02/2003 Federal Republic of Germany 20/03/2002 Rec 980 at 18/02/2005

235 East 42nd Street, New York, Filing date: 25/03/2002 Pfizer Inc. Warrant signed on 1703 Phenyl heterocyclyl ethers NY 10017, United States of Rec: 1005/6 dt Wef: 11/04/2001 Vide PT 1703 Attn: Lysaght & Co. 15/10/2003 America 25/03/2002 Method for Manufacturing a Low Filing date: 25/03/2002 Dose Pharmaceutical Pfizer Products Inc. Eastern Point Road, Groton, Wef: 01/05/2001 Warrant Signed on 1704 Rec: 1003/4 dt Vide PT 1704 Composition having Uniform Drug Att: Lysaght & Co. Connecticut 06340, USA 16/07/2003 25/03/2002 Distribution and Potency

Filing date: 27/03/2002 Wetfast Polyamide Fiber with a Honeywell International Inc. 101 Columbia Road, Morristown, Warrant Signed on 1705 Rec: 1037/8 dt Wef: 30/03/2001 Vide PT 1705 High Amine End Group Content Attn: S S& Co. New Jersey 07962, USA 21/01/2003 01/04/2002

Filing date: 01/04/2002 Fused Bicyclic or Tricyclic Amino Warner - Lambert Company 201 Tabor Road Morris Plains, Warrant signed on 1706 Rec: 1068/9 dt Wef: 19/04/2001 Vide PT 1706 Acids Attn: Lysaght & Co New Jersey 07950, USA 01/08/2003 02/04/2002

800 North Lindburgh Blvd 04c, St. Filing date: 03/04/2002 Reconstitutable Parenteral Pharmacia Corporation Warrant signed on 1707 Louis, Missouri 63167, United Rec: 1120/1 dt Wef: 03/04/2001 Vide PT 1707 Composition Att: S S & Co. 06/02/2003 States of America 04/04/2002

Citrate Salt 0f 5,7,14,- triazatetracyclo[10.3.1.0211.04.9] - Filing date: 15/04/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1710 hexadeca-2(11), 3,5,7,9-Pentaene Rec: 1235/6 dt Wef: 14/05/2001 Vide PT 1710 Att: Lysaght & Co. Connecticut 06340, USA 29/08/2003 and Pharmaceutical Compositions 15/04/2002 thereof

Tartrate Salts of 5, 7,14 - Triazatetracyclo Filing date: 15/04/2002 [10.3.1.02.,11.04,9] - hexadeca - Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1711 Rec: 1233/4 dt Wef: 14/05/2001 Vide PT 1711 2(11),3,5-9 pentaene and Att: Lysaght & Co. Connecticut 06340, USA 01/08/2003 15/04/2002 pharmaceutical compositions thereof

Filing date: 30/04/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1713 Antibacterial Agents Rec: 1406/7 dt Wef: 30/05/2001 Vide PT 1713 Att: Lysaght & Co New Jersey 07950, USA 08/10/2003 30/04/2002

Filing date: 06/05/2002 Liquid Pharmaceutical Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1714 Rec: 1485/6 dt Wef: 25/05/2001 Vide PT 1714 Composition Att: Lysaght & Co New Jersey 07950, USA 15/10/2003 06/05/2002

Filing date: 13/05/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1715 Crystal Forms of Azithromycin Rec: 1675/6 dt Wef: 22/05/2001 Vide PT 1715 Att: Lysaght & Co. Connecticut 06340, USA 29/08/2003 17/05/2002 Thiazole Benzamide Derivatives Filing date: 13/05/2002 and Pharmaceutical Compositions Agouron Pharmaceutical 10350 North Torrey Pines Road, Warrant signed on 1716 Rec: 1677/8 dt Wef: 06/07/2001 Vide PT 1716 for Inhibiting Cell Proliferation and Att: Dr. R. Frendo Randon La Jolla, CA 92037, USA 29/08/2003 17/05/2002 Methods for their Use

System Comprising a Polyamide Filing date: 15/05/2002 BASF Aktiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1717 and a 2,6- diaminopyridine Rec: 1679/80 of Wef: 15/05/2001 Vide PT 1717 Att: S S & Co. Republic of Germany 26/03/2003 Derivative and Preparation thereof 17/05/2002

Filing date: 21/05/2002 BASF Aktiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1721 Polymeric Material Rec: 1723/4 dt Wef: 22/05/2001 Vide PT 1721 Att: S S & Co. Republic of Germany 26/03/2003 21/05/2002

Filing date: 21/05/2002 Method of making a Polymer from BASF Corporation, Mount Dive, New Jersey 07828- Warrant signed on 1722 Rec: 1721/2 dt Wef: 06/06/2001 Vide PT 1722 a Polymer Precursor Composition Att: S S & Co. 1234, USA 13/03/2003 21/05/2002

AA2a Agonist and an Anti- 235 East 42nd Street, New York Filing date: 24/05/2002 cholinergic Agent in Combination, Pfizer Inc Warrant Signed on 1723 NY 10017, United States of Rec: 1841/2 dt Wef: 25/05/2001 Vide PT 1723 for Treating Obstructive Airways Att: Lysaght & Co. 30/09/2003 America 29/05/2002 Disease

A PDE4 Inhibitor and An Anti- 235 East 42nd Street, New York Filing date: 24/05/2002 cholinergic Agent in Combination Pfizer Inc Warrant Signed on 1724 NY 10017, United States of Rec: 1839/40 dt Wef: 25/05/2001 Vide PT 1724 for Treating Obstructive Airways Att: Lysaght & Co. 15/10/2003 America 29/05/2002 Diseases

Filing date: 30/05/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1725 Antibacterial Agents Rec: 1886/7 dt Wef: 19/06/2001 Vide PT 1725 Att: Lysaght & Co New Jersey 07950, USA 02/09/2003 30/05/2002

Filing date: 30/05/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1726 Novel Sulfonic Acid Derivatives Rec: 1884/5 dt Wef: 20/06/2001 Vide PT 1726 Att: Lysaght & Co. Connecticut 06340, USA 03/11/2003 30/05/2002

Self-Emulsifying Formulations of Filing date: 30/05/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1727 cholesteryl ester Transfer Protein Rec: 1882/3 dt Wef: 21/06/2001 Vide PT 1727 Att: Lysaght & Co. Connecticut 06340, USA 03/11/2003 Inhibitors 30/05/2002

Filing date: 30/05/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1728 Chiral Salt Resolution Rec: 1880/1 dt Wef: 31/05/2001 Vide PT 1728 Att: Lysaght & Co. Connecticut 06340, USA 15/10/2003 30/05/2002 HIV Protease Inhibitors, Agouron Pharmaceuticals Filing date: 11/06/2002 Compostions containing the 10350 North Torrey Pines Road, Warrant signed on 1730 Inc. Rec: 2062/3 dt Wef: 11/06/2001 Vide PT 1730 same, their Pharmaceutical uses La Jolla, CA 92037, USA 29/08/2003 Att: Lysaght and Co. 13/06/2002 and Materials for their Synthesis

Crystalline Forms of [R-(R*,R*)]-2- (4-fluorophenyl)-B, 8-Dihydroxy-5- Filing date: 11/06/2002 (1-methylethyl)-3-phenyl-4- Warner - Lambert Company 201 Tabor Road Morris Plains, Warrant signed on 1732 Rec: 2058/9 dt Wef: 29/06/2001 Vide PT 1732 [(phenylamino)carbonyl]-1H- Att: Lysaght & Co New Jersey 07950, USA 30/09/2003 13/06/2002 pyrrole-1- heptanic acid calcium salt (2:1)

3000 Continental Drive-North, Filing date: 12/06/2002 Light-stabilized Polymeric Articles Basf Corporation Warrant signed on 1733 Mount olive, New Jersey 08728- Rec: 2056/7 dt Wef: 14/06/2001 Vide PT 1733 and Methods for Making the Same Att: S S & Co. 26/03/2003 1234, USA 13/06/2002

HIV Protease Inhibitors, Agouron Pharmaceuticals Filing date: 11/06/2002 Compostions containing the 10350 North Torrey Pines Road, Warrant signed on 1735 Inc. Rec: 2054/5 dt Wef: 11/06/2001 Vide PT 1735 same, their Pharmaceutical uses La Jolla, CA 92037, USA 29/08/2003 Att: Lysaght and Co. 13/06/2002 and Materials for their Synthesis

Pharmaceutical Compositions Filing date: 18/06/2002 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1736 Containing Polymer and Drug Rec: 2155/6 dt Wef: 22/06/2001 Vide PT 1736 Att: Lysaght & Co. Connecticut 06340, USA 29/08/2003 Assemblies 19/06/2002

Filing date: 18/06/2002 5-HT Receptor Ligands and Uses Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1737 Rec: 2153/4 dt Wef: 21/06/2001 Vide PT 1737 thereof Att: Lysaght & Co. Connecticut 06340, USA 23/06/2004 19/06/2002

Filing date: 19/06/2002 BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1738 Multimodal Polymer Mixtures Rec: 2174/5 dt Wef: 21/06/2001 Vide PT 1738 Att: S S & Co. Republic of Germany 06/02/2003 19/06/2002

Filing date: 19/06/2002 BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1739 Polymer Mixtures Rec: 2172/3 dt Wef: 21/06/2001 Vide PT 1739 Att: S S & Co. Republic of Germany 06/02/2003 19/06/2002

Filing date: 19/06/2002 BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1740 Highly Stabilized Polymer Rec: 2170/1 dt Wef: 21/06/2001 Vide PT 1740 Att: S S & Co. Republic of Germany 30/09/2003 19/06/2002 Filing date: 19/06/2002 Multimodal Polyamides, BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1741 Rec: 2168/9 dt Wef: 21/06/2001 Vide PT 1741 Polyesters and Polyesteramides Att: S S & Co. Republic of Germany 06/02/2003 19/06/2002

Filing date: 19/06/2002 BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1742 Thermoplastic Polymer Mixtures Rec: 2166/7 dt Wef: 21/06/2001 Vide PT 1742 Att: S S & Co. Republic of Germany 26/03/2003 19/06/2002

235 East 42nd Street, New York, Filing date: 21/06/2002 Spiropiperidine Compounds as Pfizer Inc. Warrant signed on 1744 NY 10017, United States of Rec: 2238/9 dt Wef: 26/06/2001 Vide PT 1744 Ligands for Drl-1 Receptor Att: Lysaght & Co. 29/08/2003 America 24/06/2002

35 Northeast Industrial Road Cycloalkylpyrrole-3-Carboxylic Neurogen Corporation & Branford, Connecticut 06405 Filing date: 01/07/2002 acid Derivatives and Warrant signed on 1745 Pfizer Products Inc. USA & Eastern Point Road Rec: 2411/2 dt Wef: 06/07/2001 Vide PT 1745 Heterocycloalkylpyrrole-3- 30/09/2003 Att: Lysaght & Co. Groton, Connecticut 06340 09/07/2002 carboxylic acid Derivatives USA

Use of Compounds in a Dry 235 East 42nd Street, New York, Filing date: 18/07/2002 Pfizer Inc. 1748 powder Inhaler and Similar NY 10017, United States of Rec: 2908/9 dt Wef: 12/09/2001 ABANDONED Vide PT 1748 Att: Lysaght & Co. Devices America 23/07/2002

1-alkyl or 1-cycloalkyltriazolo [4,3- Filing date: 18/07/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1749 a] quinazolin-5-ones as Rec: 2910/1 dt Wef: 13/08/2001 Vide PT 1749 Att: Lysaght & Co New Jersey 07950, USA 29/08/2003 phosphodiesterase Inhibitors 23/07/2002

235 East 42nd Street, New York, Filing date: 18/07/2002 Process for the Production of Pfizer Inc. Warrant signed on 1750 NY 10017, United States of Rec: 2912/3 dt Wef: 01/08/2001 Vide PT 1750 Quinazolines Att: Lysaght & Co. 22/11/2005 America 23/07/2002

Filing date: 25/07/2002 Preparation of Anhydrous CETP Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1752 Rec: 2921/2 dt Wef: 28/09/2001 Vide PT 1752 Inhibitors Att: Lysaght & Co. Connecticut 06340, USA 12/03/2004 23/07/2002

Filing date: 25/07/2002 Pharmaceutical Compositions of Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1753 Rec: 2923/4 dt Wef: 31/07/2001 Vide PT 1753 Amlodipineand Atorvastatin Att: Lysaght & Co New Jersey 07950, USA 29/08/2003 23/07/2002

Via Cantonale 658A, 7745 Filing date: 01/08/2002 Process for the Preparation of 5- Infosint SA Warrant signed on 1755 Poschiavo, Cantoni dei Grigioni, Rec: 3302/3 dt Wef: 02/08/2001 Vide PT 1755 Formylphtalide Att: S S & Co. 09/07/2003 Switzerland 02/08/2002 Via Cantonale 658A, 7745 Filing date: 01/08/2002 Process for the Preparation of 5- Infosint SA Warrant signed on 1756 Poschiavo, Cantoni dei Grigioni, Rec: 3299/3300 dt Wef: 02/08/2001 Vide PT 1756 Substituted Isobenzofurans Att: S S & Co. 09/07/2003 Switzerland 02/08/2002

Filing date: 06/08/2002 Novel Crude and Crystalline forms Recordati Ireland Limited 17, The Crescent , Limerick, Warrant signed on 1757 Rec: 3610/1 dt Wef: 06/08/2001 Vide PT 1757 of Lercanidipine Hydrochloride Att: S S & Co. Ireland 09/07/2003 12/08/2002

Solvates of Lercanidipine Hydrochloride and New Filing date: 06/08/2002 Recordati Ireland Limited 17, The Crescent , Limerick, Warrant signed on 1758 Crystalline forms of Lercanidipine Rec: 3606/7 dt Wef: 06/08/2001 Vide PT 1758 Att: S S & Co. Ireland 16/07/2003 Hydrochloride obtained from said 12/08/2002 Solvates

Filing date: 09/08/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Rec: 3612/3 dt Warrant signed on 1759 Antidiabetic agents Wef: 29/08/2001 Vide PT 1759 Att: Lysaght & Co New Jersey 07950, USA 12/08/2002 06/02/2004

Transfer Device and Cap Bristol-Myers Squibb Filing date: 28/08/2002 PO Box 4000, 08543-4000 Warrant signed on 1760 Assembly for Use with a Container Company Rec: 4202/3 dt Wef: 17/12/2001 Vide PT 1760 Princeton, New Jersey, United 10/04/2003 and the Transfer Device Att: S S & Co. 29/08/2002 States of America

235 East 42nd Street, New York, Filing date: 29/08/2002 Use of a Combination of Pfizer Inc. Warrant signed on 1761 NY 10017, United States of Rec: 4319/20 dt Wef: 12/09/2001 Vide PT 1761 Compounds in a Dry Inhaler Att: Lysaght & Co. 01/08/2003 America 03/09/2002

Use of Compounds in a Dry 235 East 42nd Street, New York, Filing date: 29/08/2002 Pfizer Inc. Warrant signed on 1762 powder Inhaler and Similar NY 10017, United States of Rec: 4322/3 dt Wef: 12/09/2001 Vide PT 1762 Att: Lysaght & Co. 16/07/2003 Devices America 03/09/2002

Low Hygoscopic Aripiprozole Otsuka Pharmaceutical Co. Filing date: 16/09/2002 2-9 Kanda - Tsukasacho, Chiyado- Warrant signed on 1763 Drug, Substance and Processes Ltd. Rec: 4689/90 dt Wef: 25/09/2001 Vide PT 1763 Ku, Tokyo, Japan 29/08/2003 for the Preparation thereof Att: S S & Co. 17/09/2002

Process for Preparing Heterocyclo Pfizer Products Inc. Filing date: 23/09/2002 Eastern Point Road, Groton, Warrant signed on 1764 - Alkylsulfonyl Pyrazole Att: S S & Co. Rec: 4882/3 dt Wef: 28/09/2001 Vide PT 1764 Connecticut 06340, USA 01/09/2003 Derivatives 23/09/2002 Pfizer Products Inc. Filing date: 26/09/2002 2-Amino-6-(2,4,5-Substituted- Eastern Point Road, Groton, Warrant signed on 1772 Att: S S & Co. Rec: 5079/81 dt Wef: 10/10/2001 Vide PT 1772 phenyl)-Pyridines Connecticut 06340, USA 05/09/2003 27/09/2002

Pfizer Inc. 235 East 42nd Street, New York, Filing date: 26/09/2002 Warrant signed on 1773 Pharmaceutical Formulations Att: S S & Co. NY 10017, United States of Rec: 5068/9 dt Wef: 11/10/2001 Vide PT 1773 12/03/2004 America 27/09/2002

Filing date: 26/09/2002 Alkyne Matrix Metalloproteinase Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1774 Rec: 5065/6 dt Wef: 12/10/2001 Vide PT 1774 Inhibitors Att: S S & Co. New Jersey 07950, USA 30/09/2003 27/09/2002

Pfizer Products Inc. Filing date: 26/09/2002 3-Azabicyclo[3.1.0.] Hexane Eastern Point Road, Groton, Warrant signed on 1775 Att: S S & Co. Rec: 5060/1 dt Wef: 22/10/2001 Vide PT 1775 Derivatives Connecticut 06340, USA 29/08/2003 27/09/2002

Filing date: 01/10/2002 New Anhydrous Crystalline Forms Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant Signed on 1776 Rec: 5190/1 dt Wef: 09/10/2001 Vide PT 1776 of Gabapentin Att: S S & Co. New Jersey 07950, USA 12/03/2004 01/10/2002

Filing date: 01/10/2002 Alkynylated Fused Ring Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1777 Rec: 5193/4 dt Wef: 12/10/2001 Vide PT 1777 Pyrimidine Compounds Att: S S & Co. New Jersey 07950, USA 12/03/2004 01/10/2002

Oral Dosage forms for Propuerine Apogepha Arzneimittel Filing Date: 08/10/2002 or Pharmaceutically Acceptable Kyffhauserstrasse 27, Dresden, Warrant signed on 1781 GMBH Rec: 5465/6 dt Wef: 09/10/2001 Vide PT 1781 Salts thereof having Prolonged Germany 16/07/2003 Att: Mamo TCV 08/10/2002 Release of the Active Agent

Pfizer Inc. 235 East 42nd Street, New York, Filing Date: 09/10/2002 Imidazopyridine Compounds as 5- Warrant signed on 1782 Att: S S & Co. NY 10017, United States of Rec: 5484/5 dt Wef: 22/10/2001 Vide PT 1782 HT4 Receptor Modulators 30/06/2003 America 09/10/2002

Filing Date: 09/10/2002 Pfizer Products Inc. Eastern Point Road, Groton, CT Warrant signed on 1783 Novel Piperazine Derivatives Rec: 5487/8 dt Wef: 22/10/2001 Vide PT 1783 Att: S S & Co. 06340, U.S.A. 30/09/2003 09/10/2002 Pfizer Inc. 235 East 42nd Street, New York, Filing date: 14/10/2002 PDE9 Inhibitors for Treating Warrant signed on 1784 Att: S S & Co. NY 10017, United States of Rec: 5742/3 dt Wef: 02/11/2001 Vide PT 1784 Cardiovascular Disorders 30/09/2003 America 16/10/2002

Pfizer Inc. 235 East 42nd Street, New York, Filing date: 21/10/2002 Combination of a Crystalline Drug Warrant signed on 1785 Att: S S & Co. NY 10017, United States of Rec: 5966/7 dt Wef: 06/12/2001 Vide PT 1785 form and atiotropuim Salt 01/08/2003 America 21/10/2002

Pfizer Inc. 235 East 42nd Street, New York, Filing Date: 21/10/2002 Warrant signed on 1786 Crystalline Drug Form Att: S S & Co. NY 10017, United States of Rec: 5968/9 dt Wef: 06/12/2001 Vide PT 1786 01/08/2003 America 21/10/2002

Filing date: 21/10/2002 Benzamide, Heteroarylamide and Pfizer Products Inc. Eastern Point Road, Groton, CT Warrant signed on 1787 Rec: 5971/2 dt Wef: 12/11/2001 Vide PT 1787 Reverse Amides Att: S S & Co. 06340, U.S.A. 01/08/2003 21/10/2002

Process for Resolution of Filing date: 29/10/2002 tamsulosin and Compouinds and Synthon B.V Microweg 22, NL-6545 CM Warrant signed on 1788 Rec: 6254/5 dt Wef: 31/10/2001 Vide PT 1788 Compositions Associated there Att: Bezzina & Mifsud Nymegen, The Netherlands 22/02/2005 29/10/2002 with

Filing Date: 29/10/2002 Racemic tamsulosin Free Base Synthon B.V Microweg 22, NL-6545 CM Warrant signed on 1789 Rec: 6257/8 dt Wef: 31/10/2001 Vide PT 1789 and Methods of making the same Att: Bezzina & Mifsud Nymegen, The Netherlands 30/09/2003 29/10/2002

Inhibitors of Factor XA and Other Filing Date: 30/10/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1790 Serine Proteases Involved in the Rec: 6324/5 dt Wef: 29/11/2001 Vide PT 1790 Att: S S & Co. New Jersey 07950, USA 30/09/2003 Coagulation Cascade 30/10/2002

Processes for the Preparation of Filing Date: 30/10/2002 Substituted Bicyclic Derivatives Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1791 Rec: 6321/2 dt Wef: 30/11/2001 Vide PT 1791 for the Treatment of Abnormal Cell Att: S S & Co. Connecticut 06340, USA 30/09/2003 30/10/2002 Growth

235 East 42nd Street, New York, Filing Date: 30/10/2002 Pfizer Inc. Warrant signed on 1792 Pharmaceutical Combination NY 10017, United States of Rec: 6318/9 dt Wef: 06/12/2001 Vide PT 1792 Att: S S & Co. 12/03/2004 America 30/10/2002

Succinic Acid Salts of 5,7,14- Triazatetracyclo (10.3.1.02, Filing Date: 30/10/2002 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1793 11.04,9)-hexadeca-2(11) 3,5,7,9- Rec: 6315/6 dt Wef: 29/11/2001 Vide PT 1793 Att: S S & Co. Connecticut 06340, USA 18/06/2004 pentaene and Pharmaceutical 30/10/2002 Compositions thereof Pharmaceutical Formulations of Filing Date: 30/10/2002 5,7,14-triazatetracyclo Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1794 Rec: 6312/3 dt Wef: 30/11/2001 Vide PT 1794 (10.3.1.02,11.04,9)-hexadeca-2(11), Att: S S & Co. Connecticut 06340, USA 18/06/2004 30/10/2002 3,5,7,9-Pentaene

Pharmaceutical Compositions and Filing Date: 30/10/2002 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1795 Methods for Administering EP2 Rec: 6309/10 dt Wef: 30/11/2001 Vide PT 1795 Att: S S & Co. Connecticut 06340, USA 18/06/2004 Receptor Selective Agonists 30/10/2002

Filing Date: 05/11/2002 BASF Alstiengesellschaft 67056 Ludwigshafen, Federal Warrant signed on 1796 Polymer Blend Rec: 6644/5 dt Wef: 19/11/2001 Vide PT 1796 Att: S S & Co. Republic of Germany 01/08/2003 05/11/2002

Diastereoselective Process for the Preparation of the antiviral agent 4- Filing date: 05/11/2002 Recordati S.A Piazza Boffalora, 4, 6830 Warrant signed on 1797 amino-1-(2-R-hydroxymethyl-[1,3] Rec: 6641/2 dt Wef: 06/11/2001 Vide PT 1797 Att: S S & Co. Chiasso, Switzerland 18/06/2004 oxa thiolan -5S-7L)-1H- Pyrimidin- 05/11/2002 2-one

Eastern Point Road Pfizer Products Inc. & Filing Date: 11/11/2002 Groton, Connecticut 06340 Warrant signed on 1800 Antibodies to CD40 Abgenix Inc. Rec: 6863/4 dt Wef: 09/11/2001 Vide PT 1800 USA & 7601Dumbarton Circle 30/09/2003 Att: S S & Co. 11/11/2002 Feement, 94555, California, USA

Triazolo [4,-3-a] pyrido [2,3-d] Filing Date: 12/11/2002 pyrimidin-5-one derivatives, Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1801 Rec: 6939/40 dt Wef: 26/11/2001 Vide PT 1801 compositions containing them, Att: S S & Co. New Jersey 07950, USA 18/06/2004 12/11/2002 method of preparation and use

Filing Date: 12/11/2002 Aryl fused azapolycyclic Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1802 Rec: 6942/3 dt Wef: 30/11/2001 Vide PT 1802 compounds Att: S S & Co. Connecticut 06340, USA 30/09/03 12/11/2002

Controlled Release Polymeric 235 East 42nd Street, New York, Filing Date: 12/11/2002 Pfizer Inc. Warrant signed on 1803 Compositions of Bone Growth NY 10017, United States of Rec: 6944/5 dt Wef: 30/11/2001 Vide PT 1803 Att: S S & Co. 30/09/2003 Promoting Compounds America 12/11/2002

Filing Date: 13/11/2002 235 East 42nd Street, New York, Pfizer Inc. Rec: 7004/5 dt Warrant signed on 1804 Pharmaceutical Combination NY 10017, United States of Wef: 07/12/2001 Vide PT 1804 Att: S S & Co. 13/11/2002 30/09/2003 America A process for the Preparation of 4- [1-hydroxy-4-[4- Filing Date: 15/11/2002 Dinanute Dipharma Spa. 5513, Pontebbana 103, Warrant signed on 1805 (hydroxypiphenylmethy)-1- Rec: P410783 dt Wef: N/A Vide PT 1805 Att: E Malllia & Associates Basiliamo, Italy 01/08/2003 piperidenyl]-butyl]-alpha, alpha- 15/11/2002 dimethylbenzeneacetic acid.

Filing Date: 19/11/2002 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1806 Novel Crystalline Compound Rec: 7209/10 dt Wef: 06/12/2001 Vide PT 1806 Att: S S & Co. Connecticut 06340, USA 30/09/2003 19/11/2002

Filing Date: 19/11/2002 Small Molecules for the Treatment Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1807 Rec: 7212/3 dt Wef: 12/12/2001 Vide PT 1807 of Abnormal Cell Growth Att: S S & Co. Connecticut 06340, USA 30/09/2003 19/11/2002

Salt forms of E-2-methoxy-N-(3-{4- (4-[3-Methyl-4-(6-methyl-pyridin-3- Filing Date: 19/11/2002 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1809 yloxy)-phenylamino]-quinazolin-6- Rec: 7218/9 dt Wef: 12/12/2001 Vide PT 1809 Att: S S & Co. Connecticut 06340, USA 05/01/2004 yl}-allyl) acetamide and method of 19/11/2002 production

235 East 42nd Street, New York, Filing date: 19/11/2002 Lactams as Tachykinin Pfizer Inc. Warrant signed on 1810 NY 10017, United States of Rec: 7221/2 dt Wef: 18/12/2001 Vide PT 1810 Antagonists Att: S S & Co. 30/09/2003 America 19/11/2002

Non-Halogenated Hydroxyalkyl- substituted Phenol Compounds, Filing Date: 19/11/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1811 Antimicrobial Compositions Rec: 7224/5 dt Wef: 20/12/2001 Vide PT 1811 Att: S S & Co. New Jersey 07950, USA 29/03/2004 containing the same and Methods 19/11/2002 of Using the same

Filing Date: 19/11/2002 Directly Compressible Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1812 Rec: 7227/8 dt Wef: 21/12/2001 Vide PT 1812 formulations of Azithromycin Att: S S & Co. Connecticut 06340, USA 12/03/2004 19/11/2002

235 East 42nd Street, New York, Filing Date: 19/11/2002 Pfizer Inc. Warrant signed on 1813 Pharmaceutical Combination NY 10017, United States of Rec: 7230/1 dt Wef: 07/12/2001 Vide PT 1813 Att: S S & Co. 30/09/2003 America 19/11/2002

Citric Acid Salt of Therapeutic Filing Date: 27/11/2002 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1814 Compound and Pharmaceutical Rec: 7649/50 dt Wef: 07/12/2001 Vide PT 1814 Att: S S & Co. Connecticut 06340, USA 30/09/2003 Compositions thereof 27/11/2002 Rubber-Latex Connected to a Filing Date: 09/12/2002 Derivative of Substituted 4,5- Consultania GmbH Planegge - Str 6, Planegg, Warrant signed on 1818 Rec: 7962/3/4 dt Wef: N/A Vide PT 1818 Coumarin with Anti-Microbial Att: Zimmiermann - Zierer Germany 28/11/2003 09/12/2002 Activity

Adsorptive Conjugate Comprising Rubber-Latex Composition and N- (7-((30-(aminocarbonyl)-5,-5-di-C- methyl-4-0-methyl-a-L- Filing Date: 09/12/2002 Consultania GmbH Planegge - Str 6, Planegg, Warrant signed on 1819 Lyxopyranosyl) oxy4-hydroxy-8- Rec: 7962/3/4 dt Wef: N/A Vide PT 1819 Att: Zimmiermann - Zierer Germany 16/07/2003 methyl-2-oxo-2H-1 benzopyran-3- 09/12/2002 yl)-4-hydroxy-3-(3-methyl-2 butenyl) benzamide on the surface with anti-microbila activity

Zirconium-indenyl-metallo- Filing date: 09/12/2002 Safetec GmbH Vom-Stein-Str No.14, Warrant signed on 1820 complex providing anti-microbial Rec: 7962/4 dt Wef: N/A Vide PT 1820 Att: Zimmiermann - Zierer Friedrichshafen, Germany 30/06/2004 activity 09/12/2002

Derivative of Substituted 1,3, Filing Date: 09/12/2002 Safetec GmbH Vom-Stein-Str No.14, Warrant signed on 1822 Thiazoles with Anti-Microbial Rec: 7962/3/4 dt Wef: N/A Vide PT 1822 Att: Zimmermann - Zierer Friedrichshafen, Germany 30/06/2004 Activity 09/12/2002

Filing Date: 09/12/2002 Mannich-Bases with Anti-Fungal Safetec GmbH Vom-Stein-Str No.14, Warrant signed on 1823 Rec 7962/4 dt Wef: N/A Vide PT 1823 Activity Att: Zimmermann - Zierer Friedrichshafen, Germany 30/06/2004 09/12/2002

Filing Date: 09/12/2002 Derivative of Isonicotinic Acid Consultania GmbH Planegge - Str 6, Planegg, Warrant signed on 1824 Rec: 7962/4 dt Wef: N/A Vide PT 1824 with Anti-Microbial Activity Att: Zimmiermann - Zierer Germany 30/06/2004 09/12/2002

N,N-Substituted Ureido- Filing Date: 09/12/2002 Safetec GmbH Vom-Stein-Str No.14, Warrant signed on 1825 Derivatives with Anti-Microbial Rec: 7962/4 dt Wef: N/A Vide PT 1825 Att: Zimmermann - Zierer Friedrichshafen, Germany 30/06/2004 Activity 09/12/2002

Covalent Conjugate Comprising Rubber- Latex Composition and Filing Date: 09/12/2002 Consultania GmbH Planegge - Str 6, Planegg, Warrant signed on 1826 Derivative of Benzoic Acid on the Rec: 7962/4 dt Wef: N/A Vide PT 1826 Att: Zimmiermann - Zierer Germany 30/06/2004 Surface with Anti-Microbial 09/12/2002 Activity 235 East 42nd Street, New York, Filing date: 10/12/2002 3-(Imidazolyl)-2-Aminopropanoic Pfizer Inc. Warrant signed on 1827 NY 10017, United States of Rec: 7977/8 dt Wef: 22/01/2002 Vide PT 1827 Acids Att: S S & Co. 08/10/2003 America 10/12/2002

235 East 42nd Street, New York, Filing Date: 10/12/2002 3-(Imidazolyl)-2-Alkoxypropanoic Pfizer Inc. Warrant signed on 1828 NY 10017, United States of Rec: 7974/5 dt Wef: 22/01/2002 Vide PT 1828 Acids Att: S S & Co. 30/09/2003 America 10/12/2002

N-(4-Substituted phenyl)- Filing Date: 18/12/2002 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1831 anthranilic acid hydroxamate Rec: 8414/5 dt Wef: 23/01/2002 Vide PT 1831 Att: S S & Co. New Jersey 07950, USA 30/09/2003 esters 19/12/2002

42 Chemin Des Olivettes, Bp7 Methods and Compositions for Rytek Filing Date: 20/12/2002 Warrant signed on 1835 34160 Saint Genies des Wef: 21/12/2001 Vide PT 1835 Treating Respiratory Pathologies Att: S S & Co. Rec: 31/2 dt 02/01/20003 12/03/2004 Mourgues, France

2-(pyridin-2-ylamino)-pyrido [2,3- Warner - Lambert Company 201 Tabor Road, Morris Plains, Filing Date: 20/12/2002 Warrant signed on 1836 Wef: 22/12/2001 Vide PT 1836 d] pyrimidin-7-ones Att: S S & Co. New Jersey 07950, USA Rec: 35/6 dt 02/01/20003 15/10/2003

N-(4-Substituted phenyl)- Warner - Lambert Company 201 Tabor Road, Morris Plains, Filing Date: 20/12/2002 Warrant signed on 1837 anthranilic acid hydroxamate Wef: 23/01/2002 Vide PT 1837 Att: S S & Co. New Jersey 07950, USA Rec: 38/9 dt 02/01/2003 30/09/2003 esters

Chewing Gum and Confectionary Compositions with Encapsulating 2711 Centerville Road, Suite 400, Cadbury Adams USA LLC Filing Date: 20/12/2002 Warrant signed on 1838 Stain Removing Agent Wilmington, Delaware 19808, Wef: 28/01/2002 Vide PT 1838 Attn: S S & Co. Rec: 41/2 dt 02/01/2003 30/09/2003 Compositions and methods of United States of America making and using the same

235 East 42nd Street, New York, Nicotinamide derivatives useful as Pfizer Inc. Filing Date: 24/12/2002 Warrant signed on 1840 NY 10017, United States of Wef: 11/02/2002 Vide PT 1840 PDE4 Inhibitors Att: S S & Co. Rec: 22/3 dt 02/01/2002 30/09/2003 America

Wef: 11/02/2002 235 East 42nd Street, New York, Nicotinamide derivatives useful as Pfizer Inc. Filing Date: 24/12/2002 Wef: 10/09/2002 Warrant signed on 1841 NY 10017, United States of Vide PT 1841 PDE4 Inhibitors Att: S S & Co. Rec: 25/6 dt 02/11/2003 Wef: 21/10/2002 09/09/2003 America Wef: 20/11/2002

Wef: 11/02/2002 Nicotinamide and a tiotropium salt 235 East 42nd Street, New York, Pfizer Inc. Filing Date: 24/12/2002 Wef: 10/09/2002 Warrant signed on 1842 in combination for the treatment NY 10017, United States of Vide PT 1842 Att: S S & Co. Rec: 28/9 dt 02/01/2003 Wef: 11/10/2002 30/09/2003 of diseases America Wef: 10/11/2002 N-Substituted Spiropiperidine 235 East 42nd Street, New York, Pfizer Inc. Filing Date: 14/01/2003 Warrant signed on 1844 compounds as ligand for ORL-1 NY 10017, United States of Wef: 28/01/2002 Vide PT 1844 Att: S S & Co. Rec: 532/3 dt 14/01/2003 30/09/2003 Receptor America

Increased - Dosage Nelfinavir 235 East 42nd Street, New York, Pfizer Inc. Filing Date: 14/01/2003 Warrant signed on 1845 Tablet and Method of making NY 10017, United States of Wef: 28/01/2002 Vide PT 1845 Att: S S & Co. Rec: 530/1 dt 14/01/2003 30/09/2003 same America

Zoniporide Mesylate Pharmaceutical Compositions and Pfizer Products Inc. Eastern Point Road, Groton, Filing Date: 14/01/2003 Warrant signed on 1846 Wef: 30/01/2002 Vide PT 1846 Processes for Improving Att: S S & Co. Connecticut 06340, USA Rec: 528/9 dt 14/01/2003 30/09/2003 Solubility of Zoniporide

Metabolites of (3-{[4-tert-butyl- benzyl)-(pyridine-3-sulfonyl)- Pfizer Products Inc. Eastern Point Road, Groton, Filing Date: 14/01/2003 Warrant signed on 1848 Wef: 31/01/2002 Vide PT 1848 amino]-methyl}-phenoxy)-acetic Att: S S & Co. Connecticut 06340, USA Rec: 523/4 dt 14/01/2003 30/09/2003 acid

Immediate Release Dosage forms Pfizer Products Inc. Eastern Point Road, Groton, Filing Date: 14/01/2003 Warrant signed on 1850 containing Solid Drugs Wef: 01/02/2002 Vide PT 1850 Att: S S & Co. Connecticut 06340, USA Rec 517/8 dt 14/01/2003 30/09/2003 Dispersions

Controlled Release Pharmaceutical Dosage forms of Pfizer Products Inc. Eastern Point Road, Groton, Filing Date: 14/01/2003 Warrant signed on 1852 Wef: 01/02/2002 Vide PT 1852 Cholesteryl Ester Transfer Protein Att: S S & Co. Connecticut 06340, USA Rec: 511/2 dt 14/01/2003 30/09/2003 Inhibitor

Pharmaceutical Compositions of Amorphous Dispersions of Drugs Pfizer Products Inc. Eastern Point Road, Groton, Filing Date: 14/01/2003 Warrant signed on 1853 Wef: 01/02/2002 Vide PT 1853 and Lipophilic Microphase - Att: S S & Co. Connecticut 06340, USA Rec: 508/9 dt 14/01/2003 30/09/2003 forming Materials

Pharmaceutical Compositions of Pfizer Products Inc. Eastern Point Road, Groton, Filing date: 21/01/2003 Warrant signed on 1855 Cholesteryl Ester Transfer Protein Wef: 01/02/2002 Vide PT 1855 Att: S S & Co. Connecticut 06340, USA Rec: 833/4 dt 22/01/2003 30/09/2003 Inhibitors

Filing date: 06/02/2003 Ziprasidone Composition and Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1856 Rec: 1561/2 dt Wef: 20/02/2002 Vide PT 1856 Synthetic Controls Att: S S & Co. Connecticut 06340, USA 31/10/2003 06/02/2003

Filing date: 06/02/2003 Pfizer Products Inc. Eastern Point Road, Groton, Rec: 1563/4 dt Warrant signed on 1857 B3- Adrenergic Receptor Agonists Wef: 27/02/2002 Vide PT 1857 Att: S S & Co. Connecticut 06340, USA 06/02/2003 31/10/2003 Filing Date: 11/02/2003 B3- Adrenergic Receptor Agonists Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on 1858 Rec: 1753/4 dt Wef: 27/02/2002 Vide PT 1858 Salt, Formulation and uses thereof Att: S S & Co. Connecticut 06340, USA 31/10/2003 11/02/2003

B3-Adrenergic Receptor Agonist Filing Date: 11/02/2003 Crystal form processes for the Pfizer Products Inc. Eastern Point Road, Groton, Rec: 1755/6 dt Warrant signed on 1859 Wef: 27/02/2002 Vide PT 1859 Production thereof, and uses Att: S S & Co. Connecticut 06340, USA 11/02/2003 31/10/2003 thereof

Combinations of an alpha-2-delta Filing Date: 18/02/2003 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1860 ligand with a selective inhibitor of Rec: 2057/8 dt Wef: 22/02/2002 Vide PT 1860 Att: S S & Co. New Jersey 07950, USA 31/10/2003 Cyclooxygenase-2 19/02/2003

Indolyl-Urea Derivatives of Filing Date: 18/02/2003 235 East 42nd Street, New York, thienopyridines usefull as anti- Pfizer Inc. Rec: 2054/5 dt Warrant signed on 1861 NY 10017, United States of Wef: 01/03/2002 Vide PT 1861 angiogenic agents, and methods Att: S S & Co. 19/02/2003 15/10/2003 America for their use.

Filing Date: 18/02/2003 Compounds that modulate PPAR Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1862 Rec: 2051/2 dt Wef: 07/03/2002 Vide PT 1862 activity Att: S S & Co. New Jersey 07950, USA 28/11/2003 19/02/2003

235 East 42nd Street, New York, Filing Date: 18/02/2003 Pfizer Inc. Warrant signed on 1863 Compounds used in Therapy NY 10017, United States of Rec: 2048/9 dt Wef: 14/03/2002 Vide PT 1863 Att: S S & Co. 28/11/2003 America 19/02/2003

Filing Date: 18/02/2003 Compounds that modulate PPAR Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1864 Rec: 2044/5 dt Wef: 07/03/2002 Vide PT 1864 activity Att: S S & Co. New Jersey 07950, USA 15/10/2003 19/02/2003

Filing Date: 18/02/2003 Compounds that modulate PPAR Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1865 Rec: 2041/2 dt Wef: 07/03/2002 Vide PT 1865 activity Att: S S & Co. New Jersey 07950, USA 31/10/2003 19/02/2003

Combination therapies for treating 235 East 42nd Street, New York, Filing Date: 25/02/2003 Pfizer Inc. Warrant signed on 1867 Methylthioadenosine NY 10017, United States of Rec: 2270/1 dt Wef: 04/03/2002 Vide PT 1867 Att: S S & Co. 31/10/2003 Phosphorylase Deficient Cells America 25/02/2003 Filing date: 25/02/2003 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1869 Oxo azabicyclic Compounds Rec: 2264/5 dt Wef: 08/03/2002 Vide PT 1869 Att: S S & Co. New Jersey 07950, USA 31/10/2003 25/02/2003

235 East 42nd Street, New York, Filing Date: 25/02/2003 Stable Hydrate of a muscarinic Pfizer Inc. Warrant signed on 1870 NY 10017, United States of Rec: 2261/2 dt Wef: 26/03/2002 Vide PT 1870 Receptor Antagonist Att: S S & Co. 31/10/2003 America 25/02/2003

Compounds that modulate PPAR Filing Date: 04/03/2003 Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1871 activity and Methods for their Rec: 2439/40 dt Wef: 05/04/2002 Vide PT 1871 Att: S S & Co. New Jersey 07950, USA 28/11/2003 Preparation 04/03/2003

Bristol-Myers Squibb Lawrenceville - Princeton Road, Filing Date: 12/03/2003 Palatable Oral Suspension and Warrant signed on 1872 Company PO Box 4000 Princeton, Rec: 2711/2 dt Wef: 12/03/2002 Vide PT 1872 Method 29/11/2003 Att: S S & Co. New Jersey 08543-400 USA 12/03/2003

Filing Date: 18/03/2003 Amino Acids with Affinity for The Warner - Lambert Company 201 Tabor Road, Morris Plains, Warrant signed on 1874 Rec: 2874/5 dt Wef: 28/03/2002 Vide PT 1874 a20- Protein Att: S S & Co. New Jersey 07950, USA 31/10/2003 18/03/2003

Triaryl-Oxy-Aryloxy-Pyrimidine- Filing Date: 18/03/2003 Pfizer Products Inc Eastern Point Road Groton, Warrant signed 1875 2,4,6-Trione Metalloproteinase Rec: 2871/2 dt Wef: 26/04/2002 Vide PT 1875 ATT: S S & Co. Connecticut 06340, USA 31/12/2003 Inhibitors 18/03/2003

N-Substituted-Heteroaryloxy-Aryl- Filing date 18/03/2003 Pfizer Products Inc Eastern Point Road Groton, Warrant signed 1876 Spiro-Pyrimidine-2,4,6-trione Rec: 2868/9 dt Wef: 26/04/2002 Vide PT 1876 ATT: S S & Co. Connecticut 06340, USA 31/12/2003 Metalloproteinase Inhibitors 18/03/2003

Aryl-Heteroaryloxy-aryloxy- Filing Date: 18/03/2003 Pfizer Products Inc Eastern Point Road Groton, Warrant signed 1877 Pyrimidine-2,4,6-Trione Rec: 2865/6 dt Wef: 26/04/2002 Vide PT 1877 ATT: S S & Co. Connecticut 06340, USA 01/10/2004 Metalloproteinase Inhibitors 18/03/2003

Bristol-Myers Squibb Lawrenceville - Princeton Road, Filing Date: 24/03/2003 Low Dose Liquid Entecavir Warrant signed on 1879 Company PO Box 4000 Princeton, Rec: 3023/4 dt Wef: 08/04/2002 Vide PT 1879 Formulations and use 28/11/2003 Att: S S & Co. New Jersey 08543-400 USA 25/03/2003

Filing Date: 24/03/2003 Tropane Derivatives Useful In Pfizer Inc Eastern Point Road Groton, Warrant signed 1880 Rec: 3026/7 dt Wef: 08/04/2002 Vide PT 1880 Therapy Attn: S S& Co. Connecticut 06340, USA 28/11/2003 25/03/2003 Polymorphic form of Rimonabant, Filing Date: 28/03/2003 method for preparing it and SANOFI-AVENTIS 174, Avenue de France FR- Warrant signed 1881 Rec: 3199/3200 dt Wef: 08/11/2001 Vide PT 1881 pharmaceutical compositions Attn: S S & Co. 75013, Paris, France 01/10/2004 01/04/2003 containing it

Pyrrolopyridazine Compounds Bristol-Myers Squibb Lawrenceville - Princeton Road, Filing Date: 28/03/2003 and Methods of use thereof for Warrant signed 1882 Company PO Box 4000 Princeton, Rec: 3202/3 dt Wef: 28/03/2002 Vide PT 1882 the treatment of Proliferative 31/10/2003 Att: S S & Co. New Jersey 08543-400 USA 01/04/2003 Disorders

Triaryl-Oxy-Aryl-Spiro-Pyrimidine- Filing Date: 01/04/2003 Pfizer Products Inc Eastern Point Road Groton, Warrant signed 1883 2,4,6-Trione Metalloproteinase Rec: 3196/7 dt Wef: 26/04/2002 Vide PT 1883 Attn: S S & Co. Connecticut 06340, USA 27/02/2004 Inhibitors 01/04/2003

Bristol-Myers Squibb Lawrenceville - Princeton Road, Filing Date: 03/04/2003 Warrant signed Oral Administration of 1884 Company PO Box 4000 Princeton, Rec: 3268/9 dt Wef: 04/04/2002 28/11/2003 Vide PT 1884 Epothilones Att: S S & Co. New Jersey 08543-400 USA 03/04/2003

Filing Date: 03/04/2003 Pfizer Products Inc Eastern Point Road Groton, Warrant signed 1885 Palatable Chewable Tablet Rec: 3271/2 dt Wef: 04/04/2002 Vide PT 1885 Attn: S S & Co. Connecticut 06340, USA 28/11/2003 03/04/2003

3,4-Dihydroquinolin-2(1H)-One Filing date 08/04/2003 Pfizer Inc Eastern Point Road Groton, Warrant signed 1886 Compounds As NR2 Receptor Rec: 3401/2 dt Wef: 26/04/2002 Vide PT 1886 Attn: S S& Co. Connecticut 06340, USA 29/11/2003 Antagonists 08/04/2003 MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Lawrenceville-Princeton Rd., P.O. Box 4000, Princeton, Bristol-Myers Squibb Heterocyclo inhibitors of New Jersey, 08543-4000, Filing Date: 08/04/2003 Warrant signed on 1887 Company & Icagen Inc. Wef: 19/4/2002 Vide PT 1887 Potassium Channel U.S.A & 422 Emperon Rec: 3403/4 dt 8/4/2003 31/12/2003 Att: SS & Co. Boulevard, Suite 350, Durham NC 27703, USA

Lawrenceville-Princeton Rd., Aryl Ketone Pyrrolo-Triazine Bristol-Myers Squibb P.O. Box 4000, Princeton, Filing Date: 22/4/2003 Warrant signed on: 1890 Compounds Useful as Kinase Company Wef: 23/04/2002 Vide PT 1890 New Jersey 08543-4000, Rec: 3793/4 dt 24/4/2003 31/12/2003 Inhibitors. Att: SS & Co. USA

Lawrenceville-Princeton Rd., Pyrrolotriazine Anline Bristol-Myers Squibb P.O. Box 4000, Princeton, Filing Date: 22/4/2003 Warrant signed on: 1891 Compounds useful as Kinase Company Wef: 23/04/2002 Vide PT 1891 New Jersey 08543-4000, Rec: 3796/7 dt 24/4/2003 31/12/2003 Inhibitors. Att: SS & Co. USA

Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 29/04/2003 Sulfonylaminovalerolactams P.O. Box 4000, Princeton, Warrant signed on: 1893 Company Rec: 3951/2 dt Wef: 06/05/2002 Vide PT 1893 and derivatives New Jersey 08543-4000, 07/07/2004 Att: SS & Co. 29/04/2003 USA

Inhibitors of hepatitis C virus RNA-dependent RNA Filing Date: 29/04/2003 Pfizer Inc 235 East 42nd Street, New Warrant signed on: 1894 polymerase, and Rec: 3948/9 dt Wef: 10/05/2002 Vide PT 1894 Att: SS & Co. York, New York, 10017, USA 31/12/2003 compositions and treatments 29/04/2003 using the same

Filing Date: 29/04/2003 Pfizer Inc 235 East 42nd Street, New Warrant signed on: 1895 Novel Combination Rec: 3945/6 dt Wef: 23/05/2002 Vide PT 1895 Att: SS & Co. York, New York, 10017, USA 19/01/2004 29/04/2003

Filing Date: 02/05/2003 A process for the preparation Dinamite Dipharma S.p.A S.S. 13 Pontebbana 103, Warrant signed on: 1896 Rec: 4037/8 dt Wef: N/A Vide PT 1896 of clopidogrel Att: E Mallia & Associates Basiliano, Italy 23/11/2004 05/05/2003

Filing Date: 02/05/2003 A process for the preparation Dinamite Dipharma S.p.A S.S. 13 Pontebbana 103, Warrant signed on: 1897 Rec: 4039/40 dt Wef: N/A Vide PT 1897 of benazepril hydrochloride. Att: E Mallia & Associates Basiliano, Italy 23/11/2004 05/05/2003

Filing Date: 02/05/2003 A process for the preparation Dinamite Dipharma S.p.A S.S. 13 Pontebbana 103, Warrant signed on: 1898 Rec: 4042/3 dt Wef: N/A Vide PT 1898 of modafinil Att: E Mallia & Associates Basiliano, Italy 23/11/2004 05/05/2003 Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 06/05/2003 Bicyclic modulators of P.O. Box 4000, Princeton, Warrant signed on: 1899 Company Rec: 4094/5 dt Wef: 17/05/2002 Vide PT 1899 Androgen Receptor New Jersey 08543-4000, 29/03/2004 Attn: SS & Co. 06/05/2003 USA

Lawrenceville-Princeton Rd., Pyrolotriazinone Compounds Bristol-Myers Squibb Filing Date: 06/05/2003 P.O. Box 4000, Princeton, Warrant signed on: 1900 and their use to treat Company Rec: 4091/2 dt Wef: 21/05/2002 Vide PT 1900 New Jersey 08543-4000, 12/03/2004 Diseases Attn: SS & Co. 06/05/2003 USA

Lawrenceville-Princeton Rd., Pyrazolo-Pyrimidine Aniline Bristol-Myers Squibb Filing Date: 06/05/2003 P.O. Box 4000, Princeton, Warrant signed on: 1901 Compounds useful as Kinase Company Rec: 4088/9 dt Wef: 20/05/2002 Vide PT 1901 New Jersey 08543-4000, 12/03/2004 Inhibitors. Attn: SS & Co. 06/05/2003 USA

Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 13/05/2003 C-Aryl Glucoside SGLT2 P.O. Box 4000, Princeton, Warrant signed on: 1907 Company Rec: 4347/8 dt Wef: 20/05/2002 Vide PT 1907 Inhibitors and Method. New Jersey 08543-4000, 12/03/2004 Attn: SS & Co. 19/05/2003 USA

Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 13/05/2003 P.O. Box 4000, Princeton, Warrant signed on: 1908 Hepatitis C Virus Inhibitors. Company Rec: 4343/4 dt Wef: 20/05/2002 Vide PT 1908 New Jersey 08543-4000, 12/03/2004 Attn: SS & Co. 19/05/2003 USA

Benzofused Heteroaryl Amide Derivatives of Thienopyridines useful as Filing Date: 13/05/2003 Pfizer Inc. 235 East 42nd Street, New Warrant signed on: 1909 Therapeutic agents, Rec: 4340/1 dt Wef: 14/06/2002 Vide PT 1909 Attn: SS & Co. York, New York 10017, USA 10/06/2004 Pharmaceutical compositions 19/05/2003 Including the same, and methods for their use

Pharmaceutical Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 13/05/2003 Compositions and Methods P.O. Box 4000, Princeton, Warrant signed on: 1910 Company Rec: 4340/1 dt Wef: 15/05/2002 Vide PT 1910 of using C-21 Modified New Jersey 08543-4000, 12/03/2004 Attn: SS & Co. 19/05/2003 Epothilone USA

Lawrenceville-Princeton Rd., Indole, Azaindole and related Bristol-Myers Squibb Filing Date: 20/05/2003 P.O. Box 4000, Princeton, Warrant signed on: 1911 Heterocyclic 4-Alkenyl Company Rec: 4391/2 dt Wef: 28/05/2002 Vide PT 1911 New Jersey 08543-4000, 06/02/2004 piperidine amides Attn: SS & Co. 20/05/2003 USA

A Pharmaceutical Filing Date: 28/05/2003 Composition having uniform Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on: 1916 Rec: 4612/3 dt Wef: 10/07/2002 Vide PT 1916 drug Distribution and Attn: SS & Co. Connecticut 06340, USA 29/03/2004 28/05/2003 Potency Filing Date: 28/05/2003 Pfizer Products Inc. Eastern Point Road, Groton, Warrant signed on: 1917 Novel Piperidine derivatives Rec: 4614/5 dt Wef: 18/07/2002 Vide PT 1917 Attn: SS & Co. Connecticut 06340, USA 29/03/2004 28/05/2003

235 East 42nd Street, New Pfizer Inc. Filing Date: 28/05/2003 Warrant signed on: 1918 Novel Combination York, New York , 10017, Wef: 26/05/2002 Vide PT 1918 Attn: SS & Co. Rec: 4617/8dt 28/05/2003 17/12/2004 USA.

Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 28/05/2003 Warrant signed on: 1919 Hand held dispenser Device. LLC Plains, New Jersey 07950, Rec: 4620/1 dt Wef: 08/07/2002 Vide PT 1919 29/03/2004 Attn: SS & Co. USA. 28/05/2003

Cedar House, 41 Cedar Avenue, Hamilton HM12, Insignion Holdings Ltd. & Filing Date: 29/05/2003 Composition and Its Bermuda & Taylor Johnson Warrant signed on: 1920 Veritron Limited, Rec: 4761/2 dt Wef: 29/05/2002 Vide PT 1920 Therapeutic Use Garrett, 50 Victoria 31/12/2003 Attn: Dr. Hugh Peralta 03/06/2003 Embarkments, Blackfriars, London EC4Y ODX, UK

Derives De I-Piperazinylacylpiperidine Filing Date: 02/06/2003 Sanofi-Aventis 174 - Avenue de France, FR- Warrant signed on: 1922 Substitutes, Leur Rec: 4740/1 dt Wef: 07/06/2002 Vide PT 1922 Att: SS & Co. 75013 Paris, France. 12/03/2004 Preparations et Leur 02/06/2003 Application en Therapeutique

Derives De Filing Date: 02/06/2003 Piperazinylacylpiperidine , Sanofi-Aventis 174 - Avenue de France, FR- Warrant signed on: 1923 Rec: 4744/5 dt Wef: 07/06/2002 Vide PT 1923 Leur Preparation et Leur Att: SS & Co. 75013 Paris, France. 12/03/2004 02/06/2003 Application en Therapeutique

Basic Non-Peptide Bradykinin Filing Date: 02/06/2003 antagonists and their Menarini Ricerche SpA Via Tito Speri, 10, Pomezia, Warrant signed on 1924 Rec: 4737/8 dt Wef: N/A Vide PT 1924 pharmaceutical compositions Att: Dr. A Perici Calascione Italy 17/12/2004 02/06/2003 therefrom.

Lawrenceville-Princeton Rd., Bristol-Myers Squibb Filing Date: 04/06/2003 Calcitonin Gene related P.O. Box 4000, Princeton, Warrant signed on: 1925 Company Rec: 4800/1 dt Wef: 05/06/2002 Vide PT 1925 peptide receptor Antagonist New Jersey 08543-4000, 16/02/2004 Attn: SS & Co. 04/06/2003 USA Use of Chloroquine, Hydroxychloroquine and 4 Aminoquinoline Derivatives to obtain a Drug for Anti- Retroviral Therapy, Active Filing Date: 09/06/2003 towards HIV sensitive strains Valpharma S.A. Via Ranco 112, Serravalle, Warrant signed on: 1926 Rec: 4912/3 dt Wef: 28/06/2002 Vide PT 1926 and towards HIV strains Att: Frendo Randon & Assoc. Republic of San Marino 12/02/2004 10/06/2003 which are resistant to both Nucleosidic and Non- Nucleosidic Reverse Transcriptase Inhibitors to proteases Inhibitors

Controlled-Release Pfizer Products Inc Eastern Point Road, Groton, Filing Date: 10/06/2003 Warrant signed on: 1927 Wef: 03/07/2003 Vide PT 1927 Pharmaceutical formulations. Attn: SS & Co. Connecticut 06340, USA Rec: 4932/3 dt 10/6/2003 05/04/2004

Filing Date: 10/06/2003 Sanofi-Aventis 174 - Avenue de France, FR- Warrant signed on: 1928 New Compounds Rec: 4936/8 dt Wef: 14/06/2003 Vide PT 1928 Att: SS & Co. 75013 Paris, France. 20/01/2004 10/06/2003

Phenyl - And Pyridyl - Filing date 17/06/03 Sanofi-Aventis 174 - Avenue de France, FR- Warrant signed on 1929 Diazaheterocycles having a Rec: 5119/20 dt Wef: 18/06/2002 Vide PT 1929 Att: SS & Co. 75013 Paris, France. 12/03/2004 TNF Modulating Activity 18/06/2003

Lawrenceville-Princeton Rd., Brtistol Myers Squibb Filing Date: 17/06/2003 Heterocyclic Inhibitors of P.O. Box 4000, Princeton, Warrant signed on 1930 Company Rec: 5122/3 dt Wef: 20/06/2002 Vide PT 1930 Kinases New Jersey 08543-4000, 16/02/2004 Attn: S S & Co 18/06/2003 USA

2,-4- Di-substituted - Pyridine Lawrenceville-Princeton Rd., Brtistol Myers Squibb Filing Date: 17/06/2003 N-oxides useful as HIV P.O. Box 4000, Princeton, Warrant signed on 1931 Company Rec: 5125/6 dt Wef: 27/06/2002 Vide PT 1931 Reverse Transcriptase New Jersey 08543-4000, 12/03/2004 Attn: S S & Co 18/06/2003 Inhibitors USA

201 Tabor Road, Morris Filing Date: 17/06/2003 Warner-Lambert Company Warrant signed on 1932 Oral Care Capsules Plains, New Jersey 07950, Rec: 5129/30 dt Wef: 16/07/2002 Vide PT 1932 Attn: Lysaght & Co. 12/03/2004 USA 18/06/2003

Eastern Point Road, Filing Date: 25/06/2003 Modulators of the Pfizer Products Inc Warrant signed on 1934 Groton, Connecticut 06340, Rec: 5334/5 dt Wef: 08/07/2002 Vide PT 1934 Glucocorticoid Receptor Attn: S S & Co. 25/06/2003 USA 25/06/2003

Filing Date: 26/06/2003 Stable Parenteral Paxocoxib Pharmacia Corporation 575, Maryville Centre Drive, Warrant signed on 1935 Rec: 5390/1 dt Wef: 26/06/2002 Vide PT 1935 sodium formulation Attn: Dr J P Chetcuti St Louis No 63141, USA 30/04/2004 26/06/2003

Substituted Amino Filing Date: 01/07/2003 Janssen Pharmaceutica NV Turnhoutseweg 30, B-2340 Warrant signed on 1936 Isoxazoline Derivatives and Rec: 5483/4 dt Wef: N/A Vide PT 1936 Attn: EMD Advocates Beerse, Belgium 02/02/2005 their use as anti-depressants 01/07/2003 Eastern Point Road, Filing Date: 01/07/2003 Pfizer Products Inc Warrant signed on 1937 Novel Piperidine Derivatives Groton, Connecticut 06340, Rec: 5525/7 dt Wef: 18/07/2002 Vide PT 1937 Attn: S S & Co. 12/03/2004 USA 01/07/2003

Substituted heterocyclic Lawrenceville - Priceton Brtistol Myers Squibb Filing Date: 02/07/2003 derivatives useful as RCL, PO Box 4000, Warrant signed on 1938 Company Rec: 5670/2 dt Wef: 09/07/2002 Vide PT 1938 antidiabetic and antiobesity Princeton, New Jersey 29/03/2004 Attn: S S & Co 04/07/2003 agents and method 08543-4000, USA

Acyloxypyrrolidine 86 Chemin de Moulare's Filing Date: 16/07/2003 derivatives, preparation SANOFI - AVENTIS Warrant signed on 1940 FR - 3400 Montpellier Rec: 6030/1 dt Wef: 19/07/2002 Vide PT 1940 thereof and application Attn: S S & Co 19/01/2004 France 16/07/2003 thereof in therapeutics

Acylaminothiazole Filing Date: 16/07/2003 derivatives, their preparation SANOFI - Synthelabo 174 Avenue de France, FR- Warrant signed on 1941 Rec: 6028/9 dt Wef: 17/07/2002 Vide PT 1941 and their therapeutic Attn: S S & Co 75013 Paris, France 05/04/2004 16/07/2003 application

Warner Lambert Company 201 Tabor Road, Morris Filing Date: 16/07/2003 Warrant signed on 1942 Kinase inhibitors LLC Plains, New Jersey NJ Rec: 6026/7 dt Wef: 25/07/2002 Vide PT 1942 29/03/2004 Attn: S S & Co 07950 16/07/2003

Lawrenceville - Priceton Brtistol Myers Squibb Filing Date: 16/07/2003 Road, PO Box 4000, Warrant signed on 1943 Novel inhibitors of Kinases Company Rec: 6023/4 dt Wef: 19/07/2002 Vide PT 1943 Princeton, New Jersey 29/03/2004 Attn: S S & Co 16/07/2003 08543-4000, USA

Filing Date: 16/07/2003 Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1944 Synergistic combinations Rec: 6020/11 dt Wef: 15/08/2002 Vide PT 1944 Attn: S S & Co. Connecticut 06340, USA 16/07/2003 16/07/2003

Filing Date: 16/07/2003 Combination therapy for Pfizer Products Inc Eastern Point Road, Groton, Warrant signed on 1945 Rec: 6017/8 dt Wef: 19/08/2002 Vide PT 1945 hyperproliferative disease Attn: S S & Co. Connecticut 06340, USA 16/07/2003 16/07/2003

Stabilised Topical A Menarini Industrie Filing Date: 22/07/2003 Via Seble Santi 3, 50131 Warrant signed on 1947 formulations containing Farmaceutiche Piunik S.R.L. Rec: 6218/9 dt Wef: 01/08/2002 Vide PT 1947 Firenze, Italy 27/02/2004 Ketoprofen Attn: S S& Co. 22/07/2003

Filing Date: 23/07/2003 Novel Mycobacterial Janssen Pharmaceutica NV Turnhoutseweg 30, B-2340 Warrant signed on 1948 Rec: P585166 dt Wef: 25/07/2002 Vide PT 1948 inhibitors Attn: EMD Advocates Beerse, Belgium 23/07/2003 23/07/2003 MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No Therapeutic Combinations of Warner-Lambert Company 201Tabor Road, Morris Filing Date: 24/07/2003 Warrant signed on 1949 ERB B Kinase Inhibitors and LLC Plains, New Jersey 07950 Wef: 07/08/2002 Vide PT 1949 Rec: 6313/4 dt 28/07/2003 10/06/2004 Antineoplastic Therapies Attn: S S & Co. , United States of America

Hetero Biaryl Derivatives as Warner-Lambert Company 201Tabor Road, Morris Filing Date: 24/07/2003 Warrant signed on 1950 Matrix Metalloproteinase LLC Plains, New Jersey 07950 Wef: 13/08/2002 Vide PT 1950 Rec: 6316/7 dt 28/07/2003 07/07/2004 Inhibitors Attn: S S & Co. , United States of America

Eastern Point Road, Pharmaceutical Pfizer Products Inc. Groton, Connecticut Filing Date: 24/07/2003 Warrant signed on 1951 Compositions of semi- Wef: 12/08/2002 Vide PT 1951 Attn: S S & Co. 06340, United States of Rec: 6318/9 dt 28/07/2003 30/04/2004 ordered drugs and Polymers America

575 Maryville Centre Pramipexole Once - Daily Pharmacia Corporation Drive, St. Louis Filing Date: 25/07/2003 Warrant signed on 1952 Wef: 25/07/2002 Vide PT 1952 Dosage Form Attn:: S S & Co. MO63141, United States Rec: 6321/2 dt 28/07/2003 27/2/2004 of America

575 Maryville Centre Sustained - Release Tablet Pharmacia Corporation Drive, St. Louis Filing Date: 25/07/2003 Warrant signed on 1953 Wef: 25/07/2002 Vide PT 1953 Composition of Pramipexole Attn:: S S & Co. MO63141, United States Rec: 6324/5 dt 28/7/2003 29/03/2004 of America

Eastern Point Road, DI and Trifluoro - Triazolo- Pfizer Products Inc. Groton, Connecticut Filing Date: 29/07/2003 Warrant signed on 1954 Pyridines Anti Inflammatory Wef: 30/08/2002 Vide PT 1954 Attn: S S & Co. 06340, United States of Rec: 6395/6 dt 29/07/2003 22/04/2004 Compounds America

Crystal Forms of Quinoxaline - 2- Carboxylic Acid [4- Eastern Point Road, Carbomoyl - 1- (3- Pfizer Products Inc. Groton, Connecticut Filing Date: 30/07/2003 Warrant signed on 1955 Wef: 12/08/2002 Vide PT 1955 Flourobenzyl) - 2,7 - Attn: S S & Co. 06340, United States of Rec: 6510/1 dt 31/07/2003 18/05/2004 Dihydroxy - 7 - Methyl - Octyl] America - Amide

Eastern Point Road, Beta - Lactamase Inhibitor Pfizer Products Inc. Groton, Connecticut Filing Date: 05/08/2003 Warrant signed on 1956 Wef: 23/08/2002 Vide PT 1956 Prodrug Attn: S S & Co. 06340, United States of Rec: 6684/5 dt 06/08/2003 22/04/2004 America

Eastern Point Road, Novel Benzoimidazole Pfizer Products Inc. Groton, Connecticut Filing Date: 05/08/2003 Warrant signed on 1957 Derivatives useful as Wef: 28/08/2002 Vide PT 1957 Attn: S S & Co. 06340, United States of Rec: 6681/2 dt 06/08/2003 30/04/2004 Antiproliferative Agents America Composition and Antiviral Bristol - Myers Squibb Lawrenceville, Princeton activity of Substituted Filing Date: 06/08/2003 Warrant signed on 1960 Company Rd, P.O. Box 4000, New Wef: 07/08/2002 Vide PT 1960 Azaindoleoxoacetic Rec: 6722/3 dt 06/08/2003 16/02/2004 Attn: S S & Co. Jersey 08543-4000, USA Piperazine Derivatives

Filing Date: 08/08/2003 N-Aryl Piperidine Substituted Janssen Pharmceutica N.V Turnhoutseweg 30, B- Warrant signed 1962 Rec: P585174 dt Wef: 12/08/2002 Vide PT 1962 Biphenyl - Carboxamides Att: EMD Advocates 2340 Beerse Belgium 18/05/2004 8/08/2003

One Amgen Centre Drive, Filing Date: 08/08/2003 Vanilloid Receptor Ligands Amgen Inc. Thousands Oaks, Warrant signed on 1963 Rec: P585176 dt Wef: 08/08/2002 Vide PT 1963 and their use in treatments Attn: CC Advocates California 91320-1799, 01/06/2004 08/08/2003 United States of America

201 Tabor Road, Morris Heterocyclic Substituted Warner - Lambert Company Plains, New Jersey Filing Date: 12/08/2003 Warrant signed on 1964 Piperazines for the treatment LLC Wef: 17/09/2002 Vide PT 1964 07950, United States of Rec: 6941/2 dt 13/08/2003 30/04/2004 of Schizophrenia Attn: S S & Co. America

Lawrenceville, Princeton Aripiprazole Complex Bristol - Myers Squibb Road, PO Box 4000, Filing Date: 12/08/2003 Warrant signed on 1965 Formulation and Method field Company Princeton, New Jersey Wef: 20/08/2002 Vide PT 1965 Rec: 6938/9 dt 13/08/2003 29/03/2004 of the Invention Attn: S S & Co. 08543 4000, United States of America

Dioxan-2-Ylalkylcarbamate Sanofi - Aventis 174 Avenue de France, Filing Date: 19/08/2003 Warrant signed on 1967 derivatives, their preparation Attn: S S & Co. Wef: 29/08/2002 Vide PT 1967 FR-75013 Paris, France Rec: 7145/6 dt 21/08/2003 29/03/2004 and their use in therapeutics

Compositions and methods for restoring immune 1124 Columbia Street, repertoire in patients with Xcyte Therapies Inc Suite 130, Seattle, Filing Date: 21/08/2003 Warrant signed 1968 immunological defects Wef: N/A Vide PT 1968 Attn: MAMO TCV Advocates Washindton, USA Rec: 7120 dt 21/08/2003 29/03/2005 related to autoimmunity and organ or hematopoietic stem cell transplantation

Novel Polymorph N-Methyl-N- (3-[2-Thienyl-Carbonyl] - 10555, Science Centre Pyrazol -[1,5-a] - Phyrimidin - Neurocrine Biosciences Inc. Filing Date: 26/08/0203 Warrant Signed on 1969 Drive, San Diego, CA, Wef: 26/08/2002 Vide PT 1969 7-YL] Phenyl) Acetamide and Attn: MAMO TCV Advocates Rec: 7306/9 dt 26/08/2003 26/02/2004 USA Compositions and methods related thereto Law Department Compositions and Methods Filing Date: 26/08/2003 Immunex Corporation 51, University Street, Warrant signed on 1970 for treating Cardiovascular Rec: 7349/50 dt Wef: 28/08/2002 Vide PT 1970 Attn: S S & Co. Seattle, WA98115, 26/09/2003 disease 27/08/2003 USA

Lawrenceville, Princeton N-Ureidoalkyl - Piperidines Bristol - Myers Squibb Road, PO Box 4000, Filing Date: 21/08/2003 Warrant signed 1971 As Modulators of Chemokine Company Wef: 12/09/2002 Vide PT 1971 Princeton, New Jersey, Rec: 7346/7 dt 27/08/2003 27/08/2003 Receptor Activity Attn: S S & Co. 08548 - 4000, USA

Heterocyclic Aromatic Lawrenceville, Princeton Bristol - Myers Squibb Compounds Useful as Road, PO Box 4000, Filing Date: 27/08/2003 Warrant signed 1972 Company Wef: 04/09/2002 Vide PT 1972 Growth Hormone Princeton, New Jersey, Rec: 7343/4 dt 27/08/2003 18/05/2004 Attn: S S & Co. Secretagogues 08548 - 4000, USA

Inhibitiors of factor XA and Warner-Lambert Company 201 Tabor Road, Morris other Serine Proteases Filing Date: 03/09/2003 Warrant signed on 1974 LLC Plains, New Jersey Wef: 11/09/2002 Vide PT 1974 involved in the coagulation Rec: 7523/4 dt 03/09/2003 29/03/2004 Attn: S S & Co. 07950, USA Cascade

707, State Road, Therapeutic Human Anti - 1L- Medarex Inc. Filing Date: 05/09/2003 Warrant signed on 1975 Princeton, New Jersey Wef: 06/09/2002 Vide PT 1975 1 R1 Monoclonal Antibody Attn: B&M Patentbureau Rec: 7674/5 dt 11/09/2003 30/07/2004 08540, USA

Substitute Heterocyclic One Amgen Centre Drive, Filing Date: 09/09/2003 Amgen Inc. Warrant signed on 1978 Compounds and methods of Thousand Oaks, CA Rec: P585179 dt Wef: 09/09/2002 Vide PT 1978 Attn: CC Advocates 18/05/2004 use 91320-1799, USA 09/09/2003

Formulations Comprising an Pharmacia Italia S.P.A Via Robert Koch 1,2, Filing Date: 10/09/2003 Warrant signed on 1979 Wef: 10/09/2002 Vide PT 1979 indoline Compound Attn: S S & Co. 20152 Milan, Italy Rec: 7690/1 dt 11/09/2003 10/03/2004

New Spirocondensed Warner-Lambert Company 201 Tabor Road, Morris Quinazolinones and their use Filing Date: 10/09/2003 Warrant signed on 1980 LLC Plains, New Jersey Wef: 17/09/2002 Vide PT 1980 as Phosphodiesterase Rec: 7695/6 dt 11/09/2003 22/04/2004 Attn: S S & Co. 07950, USA Inhibitors

Novel Oxazole and Thiazole Eastern Point Road, Compounds as Transforming Pfizer Products Inc. Filing Date: 10/09/2003 Warrant signed on 1981 Groton, Connecticut Wef: 18/09/2002 Vide PT 1981 Growth Factor (TGF) Attn: S S & Co. Rec: 7695/6 dt 11/09/2003 22/04/2004 06340, USA Inhibitors

Novel Isothiazole and Eastern Point Road, Isoxazole Compounds as Pfizer Products Inc. Filing Date: 10/09/2003 Warrant signed on 1982 Groton, Connecticut Wef: 18/09/2002 Vide PT 1982 Transforming Growth Factor Attn: S S & Co. Rec: 7701/2 dt 11/09/2003 22/04/2004 06340, USA (TGF) Inhibitors Novel Inidazole Compounds Eastern Point Road, Pfizer Products Inc. Filing Date: 10/09/2003 Warrant signed on 1983 as Transforming Growth Groton, Connecticut Wef: 18/09/2002 Vide PT 1983 Attn: S S & Co. Rec: 7704/5 dt 11/09/2003 30/04/2004 Factor (TGF) Inhibitors 06340, USA

Lawrenceville - Princeton Bristol - Myers Squibb Filing Date: 10/09/2003 Compounds for the treatment Rd, PO Box 4000, Warrant signed on 1984 Company Rec: 7707/8 dt 11/09/2003 Wef: 18/09/2002 Vide PT 1984 of Premature Ejaculation Princeton New Jersey 30/04/2004 Attn: S S & Co. 08543-4000 USA

Novel Pyrazole Compounds Eastern Point Road, Pfizer Products Inc. Filing Date: 10/09/2003 Warrant signed on 1985 as Transforming Growth Groton, Connecticut Wef: 18/09/2002 Vide PT 1985 Attn: S S & Co. Rec: 7710/1 dt 11/09/2003 01/06/2004 Factor (TGF) Inhibitors 06340, USA

N-Substituted Piperidinyl - 235 East 42nd Street, Imidazopyridine Compounds Pfizer Inc. Filing Date: 12/09/2003 Warrant signed on 1988 New York, New York Wef: 20/09/2002 Vide PT 1988 as 5-HT4 Receptor Att: S S & Co. Rec: 7876/8 dt 19/09/2003 18/05/2004 10017 USA Modulators

235 East 42nd Street, Imidazopyridine Compounds Pfizer Inc. Filing Date: 12/09/2003 Warrant signed on 1989 New York, New York Wef: 20/09/2002 Vide PT 1989 as 5-HT4 Receptor Agonists Att: S S & Co. Rec: 7880/1 dt 19/09/2003 30/04/2004 10017 USA

Heterocyclic Substituted Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 12/09/2003 Warrant signed on 1990 Piperazines for the treatment LLC Plains, New Jersey Rec: 7883/4 dt 19/09/2003 Wef: 26/09/2002 Vide PT 1990 30/04/2004 of Schizophrenia Attn: S S & Co. 07950, USA

Novel Triazole Compounds Eastern Point Road, Pfizer Products Inc. Filing Date: 18/09/2003 Warrant signed on 1992 as Transforming Growth Groton, Connecticut Wef: 18/09/2002 Vide PT 1992 Attn: S S & Co. Rec: 7857/8 dt 19/09/2003 18/03/2004 Factor (TGF) Inhibitors 06340, USA

Peptides and Related One Amgen Centre Drive, Filing Date: 19/09/2003 Amgen Inc. Warrant signed on 1996 Molecules that Modulate Thousand Oaks, CA Rec: P585189 dt Wef: 18/09/2003 Vide PT 1996 Attn: CC Advocates 30/04/2004 nerve Growth factor Activity 91320-1799, USA 25/09/2003

Thiazole Compounds for the Eastern Point Road, Pfizer Products Inc. Filing Date: 23/09/2003 Wef: 09/10/2002 Warrant signed on 1997 treatment of Groton, Connecticut Vide PT 1997 Attn: S S & Co. Rec: 8043/4 dt 24/09/2003 Wef: 17/06/2003 11/05/2004 neurodegenerative disorders 06340, USA

Bristol - Myers Squibb PYRIDINO AND PYRIMIDINO P.O. Box 4000, Princeton, Filing Date: 23/09/2003 Warrant signed on 1998 Company Wef: 30/09/2002 Vide PT 1998 PYRAZINONES No. 5, 08543-4000, USA Rec: 8046/7 dt 24/09/2003 30/04/2004 Attn: S S & Co.

1;4 - Diazabicyclo [3.2.2.] Nonanecarboxamide Filing Date: 24/09/2003 Sanofi - Aventis 174 Avenue de France, Warrant signed on 1999 Derivatives, Preparation Rec: 80641/5 dt Wef: 08/10/2002 Vide PT 1999 Attn: S S & Co. FR-75013 Paris, France 10/06/2004 thereof and therapeutic use 24/09/2003 thereof Filing Date: 01/10/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2002 Therapeutic Treatment Rec: 8293/4 dt 01/10/2003 Wef: 09/10/2002 Vide PT 2002 Attn: S S & Co. Sweden 01/06/2004

Filing Date: 01/10/2003 Astrazeneca AB SE-151 85 Sodertalje, Wef: 11/10/2002 Warrant signed on 2003 Chemical Compounds Rec: 8290/1 dt 01/10/2003 Vide PT 2003 Attn: S S & Co. Sweden Wef: 07/05/2003 01/06/2004

Novel Combination of a Bristol - Myers Squibb Filing Date: 01/10/2003 P.O. Box 4000, Princeton, Warrant signed on 2004 Factor Xa Inhibitor and Company Rec: 8287/8 dt 01/10/2003 Wef: 02/10/2002 Vide PT 2004 No. 5, 08543-4000, USA 30/04/2004 Clopidogrel Attn: S S & Co.

"Indazolecarboxamide Sanofi - Aventis 174 Avenue de France, Filing Date: 01/10/2003 Warrant signed on 2005 Derivatives, Their Preparation Wef: 02/10/2002 Vide PT 2005 Attn: S S & Co. FR-75013 Paris, France Rec: 8284/5 dt 01/10/2003 19/08/2004 and their use in Therapy"

Synergistic Methods and Bristol - Myers Squibb P.O. Box 4000, Princeton, Filing Date: 01/10/2003 Warrant signed on 2006 Compositions for Treating Company Wef: 02/10/2002 Vide PT 2006 No. 5, 08543-4000, USA Rec: 8281/2 dt 01/10/2003 18/05/2004 Cancer Attn: S S & Co.

Synergistic Methods and Bristol - Myers Squibb P.O. Box 4000, Princeton, Filing Date: 02/10/2003 Warrant signed on 2007 Compositions for Treating Company Wef: 02/10/2002 Vide PT 2007 No. 5, 08543-4000, USA Rec: 8774/5 dt 14/10/2003 18/05/2004 Cancer Attn: S S & Co.

Indole Derivatives useful for Pfizer Inc. 235, East 42nd Street, Filing Date: 03/10/2003 Wef: 11/10/2002 Warrant signed on 2008 Vide PT 2008 the treatment of Diseases Attn: S S & Co. New York 10017, USA Rec: 8384/5 dt 03/10/2003 Wef: 10/01/2003 01/06/2004

Substituted 1, 4-D1-Piperidin- 4-YL-Piperazine Derivatives Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 07/10/2003 Warrant signed on 2009 Wef: 08/10/2002 Vide PT 2009 and their use as Neurokinin ATT: Ellul Mifsud & Debono 2340 Beerse, Belgium Rec: 8508/9 dt 07/10/2003 01/06/2004 Antagonists

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 09/10/2003 Warrant signed on 2011 Therapeutic Treatment Wef: 12/10/2002 Vide PT 2011 Attn: S S & Co. Sweden Rec: 8596/7 dt 09/10/2003 11/05/2004

Human Anti-IFN-2 Medarex Inc. 707 State Road, Neutralizing antibodies as Filing Date: 13/10/2003 Wef: 16/10/2003 Warrant signed on 2012 Attn: B&M Patentbureau Princeton, New Jersey Vide PT 2012 selective IFN-2 Pathway Rec: 8755/6 dt 14/10/2003 Wef: 17/06/2003 18/05/2004 08540, USA Inhibitors One Amgen Centre Drive, Filing Date: 17/10/2003 Vanilloid Receptor Ligands Amgen Inc. Thousand Oaks, Warrant signed on 2015 Rec: P585196 dt Wef: 17/10/2002 Vide PT 2015 and their use in treatments Attn: CC Advocates California 91320 - 1799, 18/05/2004 17/10/2003 United States of America

Eastern Point Road Novel Injectable Depot Pfizer Products Inc. Filing Date: 20/10/2003 Warrant signed on 2016 Groton, Connecticut Wef: 25/10/2002 Vide PT 2016 Formulations Attn: S S & Co. Rec: 8972/3 dt 20/10/2003 01/06/2004 06340, USA

Eastern Point Road Filing Date: 20/10/2003 Depot Formulations in the Pfizer Products Inc. Warrant signed on 2017 Groton, Connecticut Rec: 8969/70 dt Wef: 25/10/2002 Vide PT 2017 form of a Suspension Attn: S S & Co. 20/10/2003 06340, USA 20/10/2003

HIV Integrase Inhibitors, 235 East 42nd Street, Pharmaceutical Pfizer Inc. Filing Date: 20/10/2003 Warrant signed on 2018 New York, New York Wef: 31/10/2002 Vide PT 2018 Compositions and Methods Attn: S S & Co. Rec: 8966/7 dt 20/10/2003 01/06/2004 10017, USA for their use

235 East 42nd Street, Therapeutic Proline Pfizer Inc. Filing Date: 20/10/2003 Warrant signed 2019 New York, New York Wef: 31/10/2002 Vide PT 2019 Derivatives Attn: S S & Co. Rec: 8963/4 dt 20/10/2003 on01/06/2004 10017, USA

Eastern Point Road Purine Compounds and uses Pfizer Products Inc. Filing Date: 20/10/2003 Warrant signed 2020 Groton, Connecticut Wef: 20/10/2002 Vide PT 2020 thereof Attn: S S & Co. Rec: 8960/1 dt 20/10/2003 01/06/2004 06340, USA

Pyridoindolone Derivatives Substituted in the 3- Position Filing Date: 22/10/2003 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2022 by a Phenyl, their Preparation Rec: 9045/6 dt 22/10/2003 Wef: 23/10/2002 Vide PT 2022 Attn: S S & Co. FR-75013 Paris, France 18/05/2004 and their Application in Therapeutics

Pyridoindolone Derivatives substituted in the 3- Position Filing Date: 22/10/2003 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2023 by a Heterocyclic Group, their Rec: 9043/4 dt 22/10/2003 Wef: 23/10/2002 Vide PT 2023 Attn: S S & Co. FR-75013 Paris, France 29/03/2004 preparation and their application in Therapeutics

Combination therapy using 1- Aminocyclohexane Merz Pharma GMBH & Co Eckenheimer Landstrasse Filing Date: 23/10/2003 Warrant signed on 2025 Derivatives and KGAA 100, D-60318 Frankfurt, Rec: 9142/3 dt 27/10/2003 Wef: 24/10/2002 Vide PT 2025 18/05/2004 Acetylcholinestrase Attn: CC Advocates Germany Inhibitors

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2026 Quinazoline Derivatives Wef: 04/11/2002 Vide PT 2026 Attn: S S & Co. Sweden Rec: 9278/9 dt 31/10/2003 09/06/2004 Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2027 Novel Compounds Wef: 07/11/2002 Vide PT 2027 Attn: S S & Co. Sweden Rec: 9281/2 dt 31/10/2003 03/06/2004

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2028 Novel Compounds Wef: 07/11/2002 Vide PT 2028 Attn: S S & Co. Sweden Rec: 9284/5 dt 31/10/2003 03/06/2004

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2029 Novel Compounds Wef: 07/11/2002 Vide PT 2029 Attn: S S & Co. Sweden Rec: 9287/8 dt 31/10/2003 03/06/2004

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2030 Novel Compounds Wef: 07/11/2002 Vide PT 2030 Attn: S S & Co. Sweden Rec: 9290/1 dt 31/10/2003 03/06/2004

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 30/10/2003 Warrant signed on 2031 Novel Compounds Wef: 12/11/2002 Vide PT 2031 Attn: S S & Co. Sweden Rec: 9292/3 dt 31/10/2003 03/06/2004

Sanofi - Aventis 174 Avenue de France, Filing Date: 04/11/2003 Warrant signed on 2032 New Compounds Wef: 15/11/2002 Vide PT 2032 Attn: S S & Co. FR-75013 Paris, France Rec: 9410/1 dt 05/11/2003 09/06/2004

Use of RMLT As a marker Eastern Point Road, Antigen for Vaccines and as Pfizer Products Inc. Groton, Connecticut Filing Date: 04/11/2003 Warrant signed on 2033 Wef: 14/11/2002 Vide PT 2033 a Synergistic Adjuvant with Attn: S S & Co. 06340, United State of Rec: 9413/4 dt 05/11/2003 03/06/2004 Amphigen America

Lawrenceville-Princeton Pharmaceutical Bristol-Myers Squibb Road , PO Box 4000, Filing Date: 07/11/2003 Warrant signed on 2034 Compositions and Methods Company Wef: 08/11/2002 Vide PT 2034 Princeton, New Jersey Rec: 9488/9 dt 07/11/2003 03/06/2004 of using Taxne Derivatives Attn: S S & Co. 08543-4000, USA

Combination Administration 230, East Grand Avenue, of an indolinone with a Sugen Inc. South San Francisco, Filing Date: 13/11/2003 Warrant signed on 2035 Wef: 15/11/2002 Vide PT 2035 Chemotherapeutic Agent for Attn: S S & Co. California 94808, United Rec: 9727/8 dt 14/11/2003 03/06/2004 cell Proliferation Disorders Sates of America

Manganyl - Oxazolidine - Filing Date: 17/11/2003 Derivatives as Promotor in Xancom Ltd Suite B, 29 Harley Street, Warrant signed on 2036 Rec: P585212 dated Wef: N/A Vide PT 2036 Nitrogene Utilization by Attn: Zimmermann & Zierer London WIG9QR, UK 02/06/2005 17/11/2003 Strains of Cholara Paradoxa N-Terminally Monopegylated 700, Chesterfield Parkway Filing Date: 20/11/2003 Human Growth Hormone Pharma Corporation West, Chesterfield Warrant signed on 2043 Rec: 9869/70 dt Wef: 20/11/2002 Vide PT 2043 Conjugates and Process for Attn: S S & Co. Missouri 63017-1732, 03/06/2004 21/11/2003 their Preparation USA

700, Chesterfield Parkway Dermal Delivery of a Water- Pharma Corporation West, Chesterfield Filing Date: 20/11/2003 Warrant signed on 2044 Soluble Selective Wef: 21/11/2002 Vide PT 2044 Attn: S S & Co. Missouri 63017-1732, Rec: 9866/7 dt 21/11/2003 03/06/2004 Cyclooxygenase - 2 Inhibitor USA

700, Chesterfield Parkway Adhesive Coated Sheet for Pharma Corporation West, Chesterfield Filing Date: 20/11/2003 Warrant signed on 2045 Dermal Delivery of Selective Wef: 21/11/2002 Vide PT 2045 Attn: S S & Co. Missouri 63017-1732, Rec: 9863/4 dt 21/11/2003 03/06/2004 Cyclooxygenase - 2 Inhibitor USA

Eastern Point Road, Pfizer Products Inc. Filing Date: 20/11/2003 Warrant signed on 2046 PPAR Activators Groton, Connecticuct Wef: 26/11/2002 Vide PT 2046 Attn: S S & Co. Rec: 9860/1 dt 21/11/2003 20/07/2007 06340, USA

800, Gateway Boulevard, Substituted Ureas and South San Francisco, Elan Pharmaceuticals Inc. & Filing Date: 27/11/2003 Carbamates useful in the California 94080, USA & Warrant signed on 2050 Pharmacia & LLP Rec: 10060/1 dt Wef: 27/11/2002 Vide PT 2050 treatment of Alzheimer's 301, Henrietta Street, 18/06/2004 Attn: B&M Patentbureau 01/12/2003 Disease Vialamazoo Midrigan 49007, USA

Filing Date: 04/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2051 New Compounds Rec:10207/8 dt Wef: 09/12/2002 Vide PT 2051 Attn: S S & Co. Sweden 24/07/2004 04/12/2003

235 East 42nd Street, Filing Date: 04/12/2003 Wef: 10/12/2002 Morpholine Dopamine Pfizer Inc. Warrant signed on 2052 New York, New York Rec: 10204/5 dt Wef: 11/04/2003 Vide PT 2052 Agonists Attn: S S & Co. 26/07/2004 10017, USA 04/12/2003 Wef: 12/06/2003

Filing Date: 04/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2053 New Compounds Rec: 10201/2 dt Wef: 17/12/2002 Vide PT 2053 Attn: S S & Co. Sweden 26/07/2004 04/12/2003

Filing Date: 04/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2054 New Compounds Rec: 10199/200 dt Wef: 17/12/2002 Vide PT 2054 Attn: S S & Co. Sweden 26/07/2004 04/12/2003

Filing Date: 04/12/2003 A new oral immediate release Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2055 Rec: 10196/7 dt Wef: 09/12/2002 Vide PT 2055 dosage form Attn: S S & Co. Sweden 26/07/2004 04/12/2003

Bicyclic Derivatives for the Eastern Point Road, Filing Date: 09/12/2003 Pfizer Products Inc. Warrant signed on 2057 treatment of abnormal cell Groton, Connecticuct Rec: 10273/4 dt Wef: 18/12/2002 Vide PT 2057 Attn: S S & Co. 26/07/2004 growth 06340, USA 09/12/2003 Complexes of E-2 - Methoxy- N - (3-{4-[3- Methyl-4-(6- Methyl-Pyridin-3-Yloxy)- Eastern Point Road, Filing Date: 09/12/2003 Pfizer Products Inc. Warrant signed on 2058 Phenylamino] - Quinazolin-6- Groton, Connecticuct Rec: 10276/7 dt Wef: 19/12/2002 Vide PT 2058 Attn: S S & Co. 30/07/2004 YL} - Allyl)-Acetamide, their 06340, USA 09/12/2003 method of Production and use

235 East 42nd Street, Filing Date: 09/12/2003 Pfizer Inc. Warrant signed on 2059 Novel Pharmaceuticals New York, New York Rec: 10279/80 dt Wef: 23/12/2002 Vide PT 2059 Attn: S S & Co. 30/07/2004 10017, USA 09/12/2003

Lawreceville-Princeton Multilayered Tablet Bristol Myers Squibb Filing Date: 09/12/2003 Rd, PO Box 4000, Warrant signed on 2060 Containing Pravastatin and Company Rec: 10282/3 dt Wef: 11/12/2002 Vide PT 2060 Princeton, New Jersey 23/06/2004 Aspirin and Method Attn: S S & Co. 09/12/2003 08543-4000, USA

Immunex Corporation & The Amgen Inc., Law Dept., Filing Date: 11/12/2003 Warrant signed on 2062 Human Pellino Polypeptides Cleveland Clinic Foundation 51 University Street, Rec: 10414/5 dt Wef: 11/12/2002 Vide PT 2062 16/06/2004 Attn: S S& Co. Seattle, WA98101, USA 15/12/2003

Eastern Point Road, Filing Date: 12/12/2003 Pfizer Products Inc. Warrant signed on 2063 Pyrrolopyrimidine Derivatives Groton, Connecticuct Rec: 10371/2 dt Wef: 19/12/2002 Vide PT 2063 Attn: S S & Co. 26/07/2004 06340, USA 12/12/2003

Eastern Point Road, Filing Date: 12/12/2003 Compounds for the treatment Pfizer Products Inc. Warrant signed on 2064 Groton, Connecticuct Rec: 10366/7 dt Wef: 20/12/2002 Vide PT 2064 of Abnormal Cell Growth Attn: S S & Co. 30/07/2004 06340, USA 12/12/2003

Dosage forms comprising a Eastern Point Road, Filing Date: 12/12/2003 Pfizer Products Inc. Warrant signed on 2065 CETP Inhibitor and an HMG- Groton, Connecticuct Rec: 10362/3 dt Wef: 20/12/2002 Vide PT 2065 Attn: S S & Co. 26/07/2004 COA Reductase Inhibitor 06340, USA 12/12/2003

Filing Date: 12/12/2003 Wef: 20/12/2002 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2066 Chemical Compounds Rec: 10359/60 dt Wef: 24/02/2003 Vide PT 2066 Attn: S S & Co. Sweden 23/06/2004 12/12/2003 Wef: 15/05/2003

Filing Date: 12/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2067 Therapeutic Agents Rec: 10356/7 dt Wef: 21/12/2002 Vide PT 2067 Attn: S S & Co. Sweden 23/06/2004 12/12/2003

Eastern Point Road, Filing Date: 12/12/2003 Novel Phosphorus - Pfizer Products Inc. Warrant signed on 2068 Groton, Connecticuct Rec: 10353/4 dt Wef: 13/12/2002 Vide PT 2068 Containing Derivatives Attn: S S & Co. 20/07/2004 06340, USA 12/12/2003 Lawrenceville-Princeton Bristol Myers Squibb Filing Date: 12/12/2003 C-6 Modified Road, PO Box 4000, Warrant signed on 2069 Company Rec: 10350/1 dt Wef: 13/12/2002 Vide PT 2069 Indazolylpyrrolotriazines Princeton, New Jersey 30/07/2004 Attn: S S & Co. 12/12/2003 08543-4000, USA

Filing Date: 16/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2070 Therapeutic Agents Rec: 10477/8 dt Wef: 24/12/2002 Vide PT 2070 Attn: S S & Co. Sweden 30/07/2004 10/12/2003

Filing Date: 16/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Wef: 24/12/2002 Warrant signed on 2071 Chemical Compounds Rec: 10474/5 dt Vide PT 2071 Attn: S S & Co. Sweden Wef: 02/06/2003 30/07/2004 16/12/2003

Eastern Point Road, Filing Date: 16/12/2003 Benzamide Inhibitors of the Pfizer Products Inc. Warrant signed on 2072 Groton, Connecticuct Rec: 10470/2 dt Wef: 31/12/2002 Vide PT 2072 P2X7 Receptor Attn: S S & Co. 30/07/2004 06340, USA 16/12/2003

Filing Date: 16/12/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2073 Therapeutic Agents Rec: 10468/9 dt Wef: 24/12/2002 Vide PT 2073 Attn: S S & Co. Sweden 30/07/2004 10/12/2003

Indazole Compounds and 235 East 42nd Street, Filing Date: 16/12/2003 Pharmaceutical compositions Pfizer Inc. Warrant signed on 2074 New York, New York Rec: 10467/6 dt Wef: 19/12/2002 Vide PT 2074 for Inhibiting protein Kinases Attn: S S & Co. 30/07/2004 10017, USA 16/12/2003 and methods for their use

Acceptably Non-Hygroscopic 700 Chesterfield Parkway, Filing Date: 16/12/2003 Formulation Intermediate Pharmacia Corporation West Chesterfield, Warrant signed on 2075 Rec: 10459/61 dt Wef: 19/12/2002 Vide PT 2075 Comprising a Hygroscopic Attn: S S & Co. Missouri 63017-1732, 20/07/2004 16/12/2003 drug USA

Pyrimidine Derivatives for the Eastern Point Road, Pfizer Products Inc. Filing Date: 16/12/03 Rec: Wef: 20/12/2002 Warrant signed on 2076 Treatment of Abnormal Cell Groton, Connecticuct Vide PT 2076 Attn: S S & Co. 10454/6 dt 16/12/2003 Wef: 05/09/2003 30/07/2004 Growth 06340, USA

Carbostyril Derivatives and Otsuka Pharmaceutical Co. 2-9, Kanda Tsukasacho, Filing Date: 19/12/2003 Serotonin Reuptake Warrant signed on 2079 Ltd. Chiyoda-Ku, Tokyo, Rec: 10572/3 dt Wef: 27/12/2002 Vide PT 2079 Inhibitors for treatment of 16/06/2004 Attn: S S & Co. Japan 22/12/2003 mood disorders

One Amgen Centre Drive, Binding agents which inhibit Amgen Inc. Thousand Oaks, Filing Date: 19/12/2003 Warrant signed on 2080 Wef: 20/12/2002 Vide PT 2080 Myostatin Attn: CC Advocates California 91320-1799, Rec: 238/9 dt 12/01/2004 26/07/2004 USA Substituted 1 - Piperidin - 4 - YL - 4 - Pyrrolidin - 3YL - Filing Date: 22/12/2003 Janssen Pharmaceutica N.V Turnhoutseweg 30, 3- Warrant signed on 2081 Piperazine Derivartives and Rec: 585226 dt Wef: 23/12/2002 Vide PT 2081 Attn: EMD Advocates 2340 Beerse, Belgium 01/09/2004 their use as Neurokinin 22/12/2003 Antagonists

Substituted 4-(4-Piperidine-4- Filing Date: 22/12/2003 YL-Piperazin-1-YL)-Azepane Janssen Pharmaceutica N.V Turnhoutseweg 30, 3- Warrant signed on 2082 Rec: P585226 dt Wef: 23/12/2002 Vide PT 2082 Derivatives and their use as Attn: EMD Advocates 2340 Beerse, Belgium 01/09/2004 22/12/2003 Neurokinin Antagonists

Substituted 1-Piperidine-3-YL- Filing Date: 22/12/2003 4-Piperidine-YL-Piperazine Janssen Pharmaceutica N.V Turnhoutseweg 30, 3- Warrant signed on 2083 Rec: P585226 dt Wef: 23/12/2003 Vide PT 2083 Derivatives and their use as Attn: EMD Advocates 2340 Beerse, Belgium 01/09/2004 22/12/2003 Neurokinin Antagonists

Substituted 1-Piperidine-4-YL- Filing Date: 22/12/2003 4-Azetidin-3-YL-Piperazine Janssen Pharmaceutica N.V Turnhoutseweg 30, 3- Warrant signed on 2084 Rec: P585226 dt Wef: 23/12/2003 Vide PT 2084 Derivatives and their use as Attn: EMD Advocates 2340 Beerse, Belgium 01/09/2004 22/12/2003 Neurokinin Antagonists

One Amgen Centre Drive, Pyrid-2-One Derivatives and Amgen Inc. Thousand Oaks, Filing Date: 22/12/2003 Wef: 27/12/2002 Warrant signed on 2085 Vide PT 2085 methods of use Attn: CC Advocates California 91320 - 1799, Rec: 234/5 dt 12/01/2004 Wef: 12/12/2003 16/06/2004 Unites States of America

One Amgen Centre Drive, WNT-1 Inhibitory Factor- Filing Date: 23/12/2003 Amgen Inc. Thousand Oaks, Warrant signed on 2086 1(WIF-1) Molecules and uses Rec: 10698/9 dt Wef: 24/12/2003 Vide PT 2086 Attn: B&M Patentbureau California 91320 - 1799, 17/08/2004 thereof 26/12/2003 Unites States of America

Law Department 51, BTL-II NUCLEIC ACIDS, Immunex Corporation Filing Date: 23/12/2003 Wef: 23/12/2002 Warrant signed on 2087 University Street, Seattle Vide PT 2087 PROTEINS AND ANTIBODIES Attn: Rec: 236/7 dt 12/01/2004 Wef: 26/11/2003 30/06/04 WA 98101, USA

(2-Carboxamido)(3-Amino) OSI Pharmaceuticals Inc. 58, South Service Road, Filing Date: 26/12/2003 Warrant signed on 2088 Wef: 02/12/2003 Vide PT 2088 Thiopene Compounds Attn: S S & Co. Melville, NY11747, USA Rec: 243/4 dt 13/01/2004 30/07/2004

One Amgen Centre Drive, Amgen Inc. Mail Stop 249A, Filing Date: 26/12/2003 Warrant signed on 2090 RNA Interference Wef: 27/12/2002 Vide PT 2090 Attn: B&M Patentbureau Thousand Oaks, Rec: 249/50 dt 13/01/2004 30/06/2004 California 91320, USA One Amgen Centre Drive, Combination Therapy with Co-Amgen Inc. Mail Stop 249A, Filing Date: 30/12/2003 Warrant signed on 2091 Wef: 30/12/2002 Vide PT 2091 Stimulatory Factors Attn: B&M Patentbureau Thousand Oaks, Rec: 246/7 - 13/01/2004 30/06/2004 California 91320, USA

Diarylmethylidene Piperidine Filing Date: 13/01/2004 Astrazeneca AB SE-15185 Sodertalje, Warrant signed on 2093 Derivatives Preparations Rec: 336/7 dt 15/01/2004 Wef: 16/01/2003 Vide PT 2093 Attn: S S & Co. Sweden 20/07/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-15185 Sodertalje, Filing Date: 13/01/2004 Warrant signed on 2094 Derivatives Preparations Wef: 16/01/2003 Vide PT 2094 Attn: S S & Co. Sweden Rec: 339/40 dt 15/01/2004 20/07/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-15185 Sodertalje, Filing Date: 13/01/2004 Warrant signed on 2095 Derivatives, preperations Wef: 16/01/2003 Vide PT 2095 Attn: S S & Co. Sweden Rec: 343/4 dt 15/01/2004 20/07/2004 thereof and uses thereof

PO Box 4000, Route 206 Bristol-Myers Squibb Methods for Inhibiting and Province line Road, Filing Date: 19/01/2004 Warrant signed on 2096 Company Wef: 23/01/2003 Vide PT 2096 Proteasome Princeton New Jersey Rec: 423/4 dt 19/01/2004 17/08/2004 Attn: S S & Co. 08543-4000, USA

Acylaminothiazole 174 Avenue de France Sanofi - Aventis Filing Date: 23/01/2004 Warrant signed on 2098 Derivatives, their preparation FR-75013 Paris Wef: 23/01/2003 Vide PT 2098 Attn: S S & Co. Rec: 556/7 dt 23/01/2004 09/07/2004 and their therapeutic use France

Arylalkylcarbamate 174 Avenue de France Derivatives, their preparation Sanofi - Aventis Filing Date: 23/01/2004 Warrant signed on 2099 FR-75013 Paris Wef: 23/01/2003 Vide PT 2099 and their application in Attn: S S & Co. Rec: 558/9 dt 23/01/2004 30/07/2004 France Therapy

PO Box 4000, Route 206 Bristol-Myers Squibb Substituted Anilide Ligands and Province line Road, Filing Date: 23/01/2004 Warrant signed on 2100 Company Wef: 24/01/2003 Vide PT 2100 for the thyroid receptor Princeton New Jersey Rec: 561/2 dt 23/01/2004 17/08/2004 Attn: S S & Co. 08543-4000, USA

Eastern Point Road Canine Vaccines Against Pfizer Products Inc. Filing Date: 26/01/2004 Warrant signed on 2101 Groton, Connecticut Wef: 29/01/2003 Vide PT 2101 Bordetella Brondiseptica Attn: S S & Co. Rec: 659/60 dt 27/01/2004 17/08/2004 06340, USA

Industrially Workable Via Della Carboneria, Filing Date: 29/01/2004 S.N.I.F.F Italia SpA Warrant signed on 2103 Synthesis of Aromatase 30/32 Localita Solomeo Rec: P585236 dt Wef: N/A Vide PT 2103 Attn: N/A 04/08/2005 Inhibitors Corciano-Perugia, Italy 29/01/2004 Via Della Carboneria, Filing Date: 29/01/2004 3-Oxime Derivative of 19- S.N.I.F.F Italia SpA Warrant signed on 2104 30/32 Localita Solomeo Rec: P585236 dt Wef: N/A Vide PT 2104 Nortestosterone Attn: N/A 04/08/2005 Corciano-Perugia, Italy 29/01/2004

17β-N-Monosubstituted Via Della Carboneria, Filing Date: 29/01/2004 S.N.I.F.F Italia SpA Warrant signed on 2105 Carbamoyl-4-Aza-5α-Androst- 30/32 Localita Solomeo Rec: P585236 dt Wef: N/A Vide PT 2105 Attn: N/A 04/08/2005 1-EN-3-One Corciano-Perugia, Italy 29/01/2004

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 02/02/2004 Warrant signed on 2106 Method of Treatment Wef: 05/01/03 Vide PT 2106 Attn: S S & Co. Sweden Rec: 8321/3 dt 02/02/2004 17/08/2004

Eastern Point Road Pyrazolo - Triazine Pfizer Products Inc. Filing Date: 02/02/2004 Warrant signed on 2109 Groton, Connecticut Wef: 06/01/2003 Vide PT 2109 Compounds and uses thereof Attn: S S & Co. Rec: 839/40 dt 02/02/2004 17/08/2004 06340, USA

Novel Invert Emulsion Type Composition Containing at Galderma Research & 635 Route des Lacides, least one active agent Filing Date: 04/02/2003 Warrant signed on 2111 Development SNC BP 87, 06902 Sophia Wef: 05/02/2003 Vide PT 2111 sensitive to the presence of Rec: 1023/4 dt 09/02/2004 26/08/2004 Attn: S S & Co. Antipolis Cedex, France water and its uses in cosmetics and dermatology

Euro-Celtique S.A Use of PVP-Iodine Liposomes 122, Boulevard de la Filing Date: 05/02/2004 Warrant signed on 2112 Attn: MAMO TCV Advocates Wef: 24/02/2003 Vide PT 2112 for treatment of acne Petrusse, Luxembourg Rec: 1013/4 dt 09/02/2004 09/11/2004

Euro-Celtique S.A Use of PVP-Iodine Liposomes 122, Boulevard de la Filing Date: 05/02/2004 Warrant signed on 2113 Attn: MAMO TCV Advocates Wef: 24/02/2003 Vide PT 2113 for Treatment of herpes Petrusse, Luxembourg Rec: 1016/7 dt 09/02/2004 09/11/2004

Euro-Celtique S.A Filing Date: 05/02/2004 Use of PVP-Iodine Liposomes 122, Boulevard de la Warrant signed on 2114 Attn: MAMO TCV Advocates Rec: 1019/20 dt Wef: 24/02/2003 Vide PT 2114 for Treatment of herpes Petrusse, Luxembourg 09/11/2004 09/02/2004

P.O.Box 4000,Route 206 Thiazolyle - Based Bristol-Myers Squibb and Province line Road, Filing Date: 05/02/2004 Warrant signed on 2115 Compounds useful as Kinase Company Princeton, New Jersey Wef: 06/02/2003 Vide PT 2115 Rec: 1005/6 dt 09/02/2004 17/08/2004 Inhibitors Attn: S S & Co. 08543-4000, United States of America

235, East 42nd Street, Filing Date: 05/02/2004 Method of Treatment for Pfizer Inc New York, New York Warrant signed on 2116 Rec: 1009/10 dt Wef: 10/02/2003 Vide PT 2116 Nelfinavir Attn: S S & Co. 10017, United States of 26/08/2004 09/02/2004 America One Amgen Centre Drive, Filing Date: 09/02/2004 Vanilloid Receptor Ligands Amgen Inc Thousand Oaks, Warrant signed on 2117 Rec: P584246 dt Wef: 10/02/2003 Vide PT 2117 and their use in treatments Attn: CC Advocates California 91320-1799, 26/08/2004 09/02/2004 USA

Warner-Lambert Company Rec 1084/5 - 201 Tabor Road, Morris LLC Filing date 09/02/04 11/02/04 2118 Depigmentation Agents Plains, New Jersey wef 11/02/03 Vide PT 2118 Attn: S S & Co. Warrant signed 17/08/04 Claims fee Lm20 07950, USA Rec 1086 - 11/02/04

P.O.Box 4000, Route 206 and Province Cyclic Derivatives as Bristol-Myers Squibb line Road Filing Date: 09/02/2004 Warrant signed on 2119 Modulators of Chemokine Company Wef: 12/02/2003 Vide PT 2119 Princeton Rec: 1087/8 dt 11/02/2004 26/08/2004 Receptor Activity ATT: Salomone, Sansone & Co New Jersey 08543-4000 United States of America

Windrush Court Wef: 11/02/2003 Tri (Cyclo) Substituted Amide Prosidion Limited Wattington Road Filing Date: 11/02/2004 Warrant signed on 2120 Wef: 11/08/2003 Vide PT 2120 Compounds Attn: S S & Co. Oxford, OX4 6 LT Rec: 1120/1 dt 12/02/2004 26/08/2004 Wef: 20/10/2003 United Kingdom

Novel Compounds which are Modulators of the ppar-type Galderma Research & 635, Route des Luciolis Filing Date: 11/02/2004 Warrant signed on 2121 receptors and their use in Development Inc. BP 57 06902 Sophia Wef: 12/02/2003 Vide PT 2121 Rec: 1123/4 dt 12/02/2004 26/08/2004 cosmetic or pharmaceutical Attn: S S & Co. Antipoles Cedex, France compositions

Novel Compounds which are modulators of the PPAR-Type Galderma Research & 635, Route des Luciolis Filing Date: 11/02/2004 Warrant signed on 2122 receptors and their use in Development Inc. BP 57 06902 Sophia Wef: 12/02/2003 Vide PT 2122 Rec: 1126/7 dt 12/02/2004 26/08/2004 cosmetic or pharmaceutical Attn: S S & Co. Antipoles Cedex, France compositons

235, East 42nd Street, Filing Date: 11/02/2004 Antiparasitic Terpene Pfizer Inc New York, New York Warrant signed on 2123 Rec: 1129/30 dt Wef: 14/02/2003 Vide PT 2123 Alkaloids Attn: S S & Co. 10017, United States of 01/10/2004 12/02/2004 America

235, East 42nd Street, Triazole compounds useful in Pfizer Inc New York, New York Filing Date: 11/02/2004 Warrant signed on 2124 Wef: 19/02/2003 Vide PT 2124 therapy Attn: S S & Co. 10017, United States of Rec: 1132/3 dt 12/02/2004 26/08/2004 America Tri (Cyclo) Substituted amide Windrush Court, Prosidion Limited Filing Date: 11/02/2004 Wef: 11/02/2003 Warrant signed on 2125 Glucokinase Activator Wattington Road, Oxford, Vide PT 2125 Attn: S S & Co. Rec: 1225/6 dt 16/02/2004 Wef: 20/10/2003 26/08/2004 Compounds OX4 6 LT, United Kingdom

235, East 42nd Street, Fused Heteroaryl Carboxylic Pfizer Inc New York, New York Filing Date: 17/02/2004 Warrant signed on 2126 Wef: 21/02/2003 Vide PT 2126 Acids as PPAR Agonists Attn: S S & Co. 10017, United States of Rec: 1326/7 dt 18/02/2004 26/08/2004 America

Pharmacia & UP John 301, Henrietta Street, Filing Date: 17/02/2004 Novel Anthelmintic and Warrant signed on 2127 Company Kalazoo Michigan 49001, Rec: 1330/1 dt 10/02/2004 Wef: 21/02/2003 Vide PT 2127 Insecticidal Compositions 26/08/2004 Attn: S S & Co. USA

Inhibitors of Hepatitis C Virus 235, East 42nd Street, RNA-Dependent RNA Filing Date: 17/02/2004 Pfizer Inc New York, New York Wef: 21/02/2003 Warrant signed on 2128 Polymerase, and Rec: 1333/4 dt 18/02/2004 Vide PT 2128 Attn: S S & Co. 10017, United States of Wef: 20/05/2003 26/08/2004 Compositions and treatments America using the same

Polymorphs of Pyrrole - Pharmacia & UP John 301, Henrietta Street, Filing Date: 17/02/2004 Warrant signed on 2129 Substituted 2-Indolinone Company Kalazoo Michigan 49001, Rec: 1337/8 dt 18/02/2004 Wef: 24/02/2003 Vide PT 2129 26/08/2004 protein Kinase Inhibitors Attn: S S & Co. USA

Highly pure fondapainux sodium composition process for preparing said 174 Avenue de France Filing Date: 18/02/2004 Sanofi-Aventis Warrant signed on 2131 composition and FR-75013 Paris Rec: 1445/6 dt 20/02/2004 Wef: 27/02/2003 Vide PT 2131 Attn: S S & Co. 24/08/2004 pharmaceutical compositions France containing it as active principle

METHOD OF TREATMENT One Amgen Center Drive, PARKINSON’S DISEASE IN Thousand Oaks, CA Amgen Inc. & University of HUMANS BY 91320, California, U.S.A. Kentucky Filing Date: 24/02/2004 Warrant signed on 2132 INTRAPUTAMINAL INFUSION & 317 Whitney- Wef: 24/02/2003 Vide PT 2132 Attn: B&M Patentbureau Rec: 1603/4 dt 25/02/2004 01/09/2005 OF GLIAL CELL-LINE Hendrickson Facility 0098 DERIVED NEUROTROPHIC Lexington Kentucky FACTOR 40536-0098 United States of America

Astrazeneca AB SE-15185 Sodertalje, Filing Date: 25/02/2004 Wef: 01/03/2003 Warrant signed on 2134 Hydroxymethyl Compounds Vide PT 2134 Attn: S S & Co. Sweden Rec: 1630/1 dt 25/02/2004 Wef: 08/08/2003 16/09/2004 Novel Fused Heteroaromatic Eastern Point Road, Pfizer Products Inc. Filing Date: 25/02/2004 Warrant signed on 2135 Compounds as Transforming Groton, Connecticut Wef: 04/03/2003 Vide PT 2135 Attn: S S & Co. Rec: 1626/7 dt 25/02/2004 01/10/2004 Growth Factor (TGF) Inhibitor 06340, USA

Wef: 07/03/2003 Novel Fused Heterocycles Astrazeneca AB SE-15185 Sodertalje, Filing Date: 25/02/2004 Wef: 15/04/2003 Warrant signed on 2136 Vide PT 2136 and Uses thereof Attn: S S & Co. Sweden Rec: 1622/3 dt 25/02/2004 Wef: 10/06/2003 16/09/2004 Wef: 24/10/2003

Toldbodgade 33, DK- Human Antibodies Specific Genmalo A/S Filing Date: 26/02/2004 Wef: 23/02/2003 Warrant signed on 2137 1253 Copengahgen K, Vide PT 2137 for Interleukin 15 (IL-15) Attn: CC Advocates Rec: 2060/1 dt 10/03/2004 Wef: 05/03/2003 26/08/2004 Denmark

Novel Ligands that Modulate 635, Route des Lucioles LXR-Type receptors, process Galderma Research & Quatier des Clausonnes Filing Date: 26/02/2004 Warrant signed on 2138 for preparing them and use Development, S.N.C Wef: 28/02/2003 Vide PT 2138 06560 Valbonne Sophia Rec: 1716/8 dt 01/03/2004 26/08/2004 thereof in human medicine Attn: S S & Co. Antipolis, France and in cosmetics

174 Avenue de France Substituted 2 - (Diaza-Bicyclo- Sanofi - Aventis Filing Date: 04/03/2004 Warrant signed on 2140 FR-75013 Paris Wef: 07/03/2003 Vide PT 2140 Alkyl) - Pyrimidone Attn: S S & Co. Rec: 1926/7 dt 05/03/2004 16/09/2004 France

Substituted 8 - Pyridenyl Dihydrospiro-[Cycloalkyl]- Phyrimido [1,2-a] Pyrimidin-6- 174 Avenue de France Filing Date: 04/03/2004 Sanofi - Aventis Warrant signed on 2141 One and 8-Pyrimidinyl- FR-75013 Paris Rec: 1929/30 dt Wef: 07/03/2003 Vide PT 2141 Attn: S S & Co. 10/06/2004 Dihydrospiro-[Cycloalkyl] - France 05/03/2004 Pyrimido[1,2-a] Pyrimidin-6- One Derivatives

Pyridyloxymethyl and Eastern Point Road, Pfizer Products Inc. Filing Date: 10/03/2004 Warrant signed on 2142 Benzisoxazole Azabicyclic Groton, Connecticut Wef: 12/03/2003 Vide PT 2142 Attn: S S & Co. Rec: 2077/8 dt 10/03/2004 16/09/2004 Derivatives 06340, USA

3-(1-[3-(1,3-Benzothiazol-6- 235, East 42nd Street, YL) Propylcarbamoyl] Pfizer Inc. Filing Date: 10/03/2004 Wef: 14/03/2003 Warrant signed on 2143 New York, New York Vide PT 2143 Cycloalkyl) Propanoic Acid Attn: S S & Co. Rec: 2081/2 dt 10/03/2004 16/12/2003 16/09/2004 100A, USA Derivatives as NEP Inhibitors

S-[2-[(1-Aminoethyl) Amino] 700, Chesterfield, Ethyl]-2-Methyl- Pharmacia Corporation Partway West, Filing Date: 10/03/2004 Warrant signed on 2144 Cysteinemaleate Wef: 11/03/2003 Vide PT 2144 Attn: S S & Co. Chesterfield, Missouri Rec: 2067/8 dt 10/03/2004 16/09/2004 Hydrochloride Crystalline 63017-1732, USA Salt Novel Lactams and uses Astiazeneca AB SE-151 85 Sodertalje, Filing Date: 10/03/2004 Wef: 14/03/2003 Warrant signed on 2145 Vide PT 2145 thereof Attn: S S & Co. Sweden Rec: 2071/2 dt 10/03/2004 Wef: 01/04/2003 16/09/2004

P.O.Box 4000, Route 206 Bristol-Myers Squibb and Province line Road, Cyclic Protein Tyrosine Filing Date: 10/03/2004 Warrant signed on 2146 Company Princeton, New Jersey Wef: 24/03/2003 Vide PT 2146 Kinase Inhibitors Rec: 2074/5 dt 10/03/2004 01/10/2004 Attn: S S & Co. 08543-4000, United States of America

Novel Fused Triazolones and Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 12/03/2004 Wef: 14/03/2003 Warrant signed on 2147 Vide PT 2147 uses thereof Attn: S S & Co. Sweden Rec: 2197/6 dt 10/03/2004 Wef: 02/05/2003 16/09/2004

Substituted 8-Perfluoroalkyl- 174 Avenue de France 6.7.8.9 Tetrahydro Sanofi - Aventis FR-75013 Paris Filing Date: 17/03/2004 Warrant signed on 2149 Wef: 21/03/2003 Vide PT 2149 Pyrimido[1.2-a] Pyrimidin-4- Attn: S S & Co. France Rec: 2332/3 dt 17/03/2004 01/10/2004 One Derivatives

174 Avenue de France 8-Substituted 6.7.8.9 - Filing Date: 17/03/2004 Sanofi - Aventis FR-75013 Paris Warrant signed on 2150 Tetrahydro - Pyrimido [1.2-a] Rec: 2329/30 dt Wef: 21/03/2003 Vide PT 2150 Attn: S S & Co. France 01/10/2004 Pyrimidin-4-One Derivatives 17/03/2004

700, Chesterfield, Dispersible Pharmaceutical Pharmacia Corporation Partway West, Filing Date: 17/03/2004 Warrant signed on 2151 Composition for Treatment of Wef: 20/03/2003 Vide PT 2151 Attn: S S & Co. Chesterfield, Missouri Rec: 2326/7 dt 17/03/2004 01/10/2004 Mastitis and Otic Disorders 63017-1732, USA

700, Chesterfield, Dispersible Formulation of an Pharmacia Corporation Partway West, Filing Date: 17/03/2004 Warrant signed on 2152 Wef: 20/03/2003 Vide PT 2152 anti-inflammatory Agents Attn: S S & Co. Chesterfield, Missouri Rec: 2323/4 dt 17/03/2004 01/10/2004 63017-1732, USA

Salts of Tricyclic Inhibitors of 235, East 42nd Street, Pfizer Inc. Filing Date: 17/03/2004 Warrant signed on 2153 Poly(ADP-Ribose) New York, New York Wef: 31/03/2003 Vide PT 2153 Attn: S S & Co. Rec: 2320/1 dt 17/03/2004 18/10/2004 Polymerases 10017, USA

Berlin-Chemie Glienicker Weg 125-127, Stabilized Topical Aktiengesallschaft & Menarini 12489 Berlin, Germany & Filing Date: 17/03/2004 Warrant signed on 2154 Formulations Containing Wef: 18/03/2003 Vide PT 2154 Ricerchi SpA Attn: S S & Via Tito Speri 10, 00040 Rec: 2523/4 dt 25/03/2004 06/10/2004 Ketoprofen Co. Pomezia, Italy

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 18/03/2003 Warrant signed on 2155 Chemical Compounds Wef: N/A Vide PT 2155 Attn: S S & Co. Sweden Rec: 2456/7 dt 23/03/2004 31/10/2005 Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 18/03/2003 Warrant signed on 2156 Chemical Compounds Wef: N/A Vide PT 2156 Attn: S S & Co. Sweden Rec: 2453/4 dt 23/03/2004 31/10/2005

Quaternary Chelidonine Dipl-ing. Dbr Wassyl Nowicky Margaretenstrasse 7 A- Filing Date: 18/03/2003 Warrant signed on 2157 Wef: 18/03/2003 Vide PT 2157 Derivatives Attn: CC Advocates 1040 Vienna, Austria Rec: 2547/8 dt 26/03/2004 01/10/2004

One Amgen Centre Drive, Heterocyclic Compounds and Amgen Inc. Filing Date: 22/03/2004 Wef: 21/03/2003 Warrant signed on 2158 Thousand Oaks California Vide PT 2158 methods of use Attn: B&M Patentbureau Rec: 2425/6 dt 23/03/2004 Wef: 19/03/2004 01/10/04 91320-1799, USA

Benzopyran Compounds for 700 Chesterfield, Parkway use in the treatment and Pharmacia Corporation West, Filing Date: 26/03/2004 Warrant signed on 2160 Wef: 31/03/2003 Vide PT 2160 prevention of Inflammation Attn: S S & Co. Chesterfield, Missouri Rec: 2587/8 dt 26/03/2004 01/10/2004 related conditions 63017-1732, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/03/2004 Warrant signed on 2161 Chemical Compounds Wef: 01/04/2003 Vide PT 2161 Attn: S S & Co. Sweden Rec: 2584/5 dt 26/03/2004 18/10/2004

Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/03/2004 Warrant signed on 2162 Derivatives Preparations Wef: 03/04/2003 Vide PT 2162 Attn: S S & Co. Sweden Rec: 2581/2 dt 26/03/2004 18/10/2004 thereof and uses thereof

Dosage Forms and methods 235, East 42nd Street, Pfizer Inc. Filing Date: 26/03/2004 Wef: 03/04/2003 Warrant signed on 2163 of Treatment using regfr New York, New York Vide PT 2163 Attn: S S & Co. Rec: 2578/9 dt 26/03/2004 Wef: 31/07/2003 18/10/2004 inhibitors 10017, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/03/2004 Warrant signed on 2164 Novel Compounds Wef: 07/04/2003 Vide PT 2164 Attn: S S & Co. Sweden Rec: 2575/6 dt 26/03/2004 18/10/2004

Eastern Point Road, Quinoline and quinoxaline Pfizer Products Inc. Filing Date: 26/03/2004 Warrant signed on 2165 Groton, Connecticut Wef: 28/03/2003 Vide PT 2165 Compounds Attn: S S & Co. Rec: 2573/4 dt 26/03/2004 01/10/2004 06340, USA

700, Chesterfield, Benzopyran Compounds Pharmacia Corporation Partway West, Filing Date: 26/03/2004 Warrant signed on 2166 useful for treating Wef: 31/03/2003 Vide PT 2166 Attn: S S & Co. Chesterfield, Missouri Rec: 2570/1 dt 26/03/2004 01/10/2004 Inflammatory Conditions 63017-1732, USA

Microfluidized oil in Water Eastern Point Road, Pfizer Products Inc. Filing Date: 26/03/2004 Warrant signed on 2167 Emulsions and vaccine Groton, Connecticut Wef: 04/04/2003 Vide PT 2167 Attn: S S & Co. Rec: 2567/8 dt 26/03/2004 18/10/2004 compositions 06340, USA 6-9, Hiranomachi 2- Chome Mitsubishi Pharma Chio-Ku, Oska-Ski 3-Substituted -4-Pyrimidone Corporation & Sanofi - Filing Date: 26/03/2004 Wef: 26/03/2003 Warrant signed on 2168 Osaka 541-0046 Vide PT 2168 Derivatives Aventis Rec: 2561/2 dt 26/03/2004 Wef: 26/03/2003 01/10/2004 Japan & 174, Avenue de Attn: S S & Co. France 75013 Paris France

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 30/03/2004 2169 Treatment of anxiety Wef: 10/04/2003 WITHDRAWN Vide PT 2169 Attn: S S & Co. Sweden Rec: 2679/1 dt 30/03/2004

235, East 42nd Street, Pfizer Inc. Filing Date: 30/03/2004 Wef: 01/04/2003 Warrant signed on 2170 Pharmaceutical Combination New York, New York Vide PT 2170 Attn: S S & Co. Rec: 2683/4 dt 30/03/2004 Wef: 30/05/2003 18/10/2004 10017, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 02/04/2004 Warrant signed on 2171 Therapeutic Treatment Wef: 05/04/2003 Vide PT 2171 Attn: S S & Co. Sweden Rec: 2832/3 dt 05/04/2004 18/10/2004

Inhibitors of cyclin - 610 Lincoln Street, dependant Kinases, BPC Bictech Inc Filing Date: 07/04/2004 Wef: 07/04/2003 Warrant signed on 2172 Waltham, Massachusetts Vide PT 2172 compositions and uses Attn: CC Advocates Rec: 3425/6 dt 26/04/2004 Wef: 23/12/2003 18/10/2004 02451, USA realted thereto

235, East 42nd Street, Alpha Substituted Carboxylic Pfizer Inc. Filing Date: 08/04/2004 Warrant signed on 2173 New York, New York Wef: 15/04/2003 Vide PT 2173 Acids as PPAR Modulators Attn: S S & Co. Rec: 3022/3 dt 13/04/2004 18/10/2004 10017, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 08/04/2004 Warrant signed on 2174 Chemical Compounds Wef: 16/04/2003 Vide PT 2174 Attn: S S & Co. Sweden Rec: 3026/7 dt 13/04/2004 18/10/2004

Eastern Point Road, Filing Date: 08/04/2004 3-Azabicyclo [3-2-1] Octane Pfizer Products Inc. Warrant signed on 2175 Groton, Connecticut Rec: 3029/30 dt Wef: 14/04/2003 Vide PT 2175 Derivatives Attn: S S & Co. 18/10/2004 06340, USA 13/04/2004

4-Phenyl-Piperidine Eastern Point Road, Compounds and their use as Pfizer Products Inc. Filing Date: 08/04/2004 Warrant signed on 2176 Groton, Connecticut Wef: 14/04/2003 Vide PT 2176 Modulators of opoid Attn: S S & Co. Rec: 3032/4 dt 13/04/2004 18/10/2004 06340, USA Receptors

METHODS OF TREATMENT One Amgen Centre Drive, USING SPECIFIC BINDING Amgen Inc Thousand Oaks, Filing Date: 12/04/2004 Warrant signed on 2177 Wef: 09/04/2003 Vide PT 2177 AGENTS OF HUMAN Attn: S S & Co. California 91320-1700, Rec: 3020/1 dt 13/04/2004 18/10/2004 ANCIOPOIETIN-2 USA One Amgen Centre Drive, Centre Drive, Thousand Amgen Inc. & Array Cyclic Amine Derivatives and Oaks, California 91320- Filing Date: 12/04/2004 Warrant signed on 2178 Biopharma Inc. Wef: 10/04/2003 Vide PT 2178 Methods of use 1799, USA & 3200 Rec: 3226/7 dt 19/04/2004 06/07/2005 Attn: B&M Patentbureau Walnut Street, Boulder, Colorado 80301, USA

One Amgen Centre Drive, Centre Drive, Thousand Amgen Inc. & Array Compounds and Methods of Oaks, California 91320- Filing Date: 12/04/2004 Warrant signed on 2179 Biopharma Inc. Wef: 06/07/2005 Vide PT 2179 use 1799, USA & 3200 Rec: 3223/4 dt 19/04/2004 06/07/2005 Attn: B&M Patentbureau Walnut Street, Boulder, Colorado 80301, USA

Compounds that Modulate Warner-Lambert Company 201, Tabor Road, Morris Filing Date: 14/04/2004 Warrant signed on 2180 PPAR Activity and Methods LLC Plains, New Jersey Wef: 17/04/2003 Vide PT 2180 Rec: 3120/1 dt 14/04/2004 09/11/2004 of Preparation Attn: S S & Co. 07950, USA

Eastern Point Road, Filing Date: 14/04/2004 Methods for Preventing Pfizer Products Inc. Warrant signed on 2181 Groton, Connecticut Rec: 3123/4 dt Wef: 21/04/2003 Vide PT 2181 Cattle Reproductive Diseases Attn: S S & Co. 09/11/2004 06340, USA 14/04/2004

Eastern Point Road, Cannabinoid receptor Pfizer Products Inc. Filing Date: 14/04/2004 Warrant signed on 2182 Groton, Connecticut Wef: 23/04/2003 Vide PT 2182 Ligands and uses thereof Attn: S S & Co. Rec: 3126/7 dt 14/04/2004 09/11/2004 06340, USA

Composition Containing Molybdenum for Controlling Xancom Ltd Suite B, 29, Harley Str Filing Date: 15/04/2004 Warrant signed on 2183 Deleterious Organisms and Atn: PRT Patent Registration Wef: N/A Vide PT 2183 London UK Rec: 3150/2 dt 15/04/2004 03/11/2005 for Stimulating Beneficial Service & Trade Ltd Organisims

Eastern Point Road, Filing Date: 16/04/2004 Cannabinoid Receptor Pfizer Products Inc. Wef: 23/04/2003 Warrant signed on 2184 Groton, Connecticut Rec: 3229/30 dt Vide PT 2184 Ligands and uses thereof Attn: S S & Co. Wef: 29/01/2004 09/11/2004 06340, USA 19/04/2004

Eastern Point Road, Cannabinoid Receptor Pfizer Products Inc. Filing Date: 16/04/2004 Warrant signed on 2185 Groton, Connecticut Wef: 23/04/2003 Vide PT 2185 Ligands and uses thereof Attn: S S & Co. Rec: 3232/3 dt 19/04/2004 09/11/2004 06340, USA

Eastern Point Road, Cannabinoid Receptor Pfizer Products Inc. Filing Date: 16/04/2004 Warrant signed on 2186 Groton, Connecticut Wef: 23/04/2003 Vide PT 2186 Ligands and uses thereof Attn: S S & Co. Rec: 3235/6 dt 19/04/2004 09/1/2004 06340, USA

201, Tabor Road Morris Fast Dissolving Orally Warner-Lambert Company Filing Date: 16/04/2004 Plains, New Jersey Warrant signed on 2187 Consumable Films Container LLC Rec: 3239/40 dt Wef: 25/04/2003 Vide PT 2187 07950, United States of 09/11/2004 Sweetener Attn: S S & Co. 19/04/2004 America Substituted Heterocyclic One Amgen Centre Drive, Amgen Inc Filing Date: 16/04/2004 Warrant signed on 2188 Compounds and Methods of Thousand Oaks, CA Wef: 16/04/2003 Vide PT 2188 Attn: CC Advocates Rec: 3421/2 dt 26/04/2004 09/11/2004 use 41320-1799, USA

800 Gateway Boulevard Elan Pharmaceuticals & South San Francisco, Phenacyl 2-Hydroxy-3- Pharmacia & Up John California 94080, USA & Filing Date: 21/04/2004 Warrant signed on 2190 Wef: 21/04/2004 Vide PT 2190 Diaminoalkanes Company 301 Henrietta Street, Rec: 3413/4 dt 26/04/2004 09/11/2004 Attn: B&M Patentbureau Kalamazoo Michigan 490071, USA

800 Gateway Boulevard Elan Pharmaceuticals & South San Francisco, Filing Date: 21/04/2004 Benzamide 2-Hydroxy-3- Pharmacia & Up John California 94080, USA & Warrant signed on 2191 Rec: 3417/8 dt Wef: 21/04/2004 Vide PT 2191 Diaminoalkanes Company 301 Henrietta Street, 09/11/2004 26/04/2004 Attn: B&M Patentbureau Kalamazoo Michigan 490071, USA

Filing Date: 22/04/2004 Wef: 28/04/2003 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2192 New heterocyclic amides Rec: 3432/3 dt Wef: 05/05/2003 Vide PT 2192 Attn: S S & Co. Sweden 09/11/2004 24/04/2004 Wef: 12/01/2004

235, East 42nd Street, Pfizer Inc. Filing Date: 22/04/2004 Wef: 29/04/2003 Warrant signed on 2193 Novel Pharmaceuticals New York, New York Vide PT 2193 Attn: S S & Co. Rec: 3436/5 dt 26/04/2004 Wef: 28/11/2003 09/11/2004 10017, USA

P.O. Box 4000 Route 206 Bristol-Myers Squibb and Province Line Rd, Filing Date: 23/04/2004 Warrant signed on 2195 HIV Integrase Inhibitors Company Princeton New Jersey Wef: 24/04/2003 Vide PT 2195 Rec: 3390/1 dt 26/04/2004 09/11/2004 Attn: S S & Co. 08543 - 4000, United States of America

2-Acylamino-4- Phenylthyiazole Derivatives Sanofi - Aventis 174 Avenue de France, Filing Date: 23/04/2004 Warrant signed on 2196 Perparation thereof and Wef: 25/04/2003 Vide PT 2196 Attn: S S & Co. FR-75013 Paris, France Rec: 3393/4 dt 26/04/2004 23/11/2004 Therapeutic Application thereof

Use of Invermectine for the Galderma S.A. Zugertrasse 8 , 6330 Filing Date: 23/04/2004 Warrant signed on 2197 Treatment of Dermatological Wef: 24/04/2003 Vide PT 2197 Attn: S S & Co. Cham, Switzerland Rec: 3396/7 dt 26/04/2004 09/11/2004 Conditions

1201 Amgen Court, West Inducers of Recombinant Immunex Corporation Filing Date: 23/04/2004 Warrant signed on 2198 Seattle, Washington, Wef: 25/04/2003 Vide PT 2198 Protein Expression Attn: MAMO TCV Advocates Rec: 3386/7 dt 26/04/2004 09/11/2004 United States of America P.O.Box 4000, Route 206 Complex of RAS- Bristol-Myers Squibb and Province Line Road, Filing Date: 27/04/2004 Warrant signed on 2199 Farnesyltransferase Inhibitor, Company Wef: 02/05/2003 Vide PT 2199 Princeton NJ08545-3000, Rec: 3562/3 dt 28/04/2004 16/09/2004 a Cyclodextrin and Ethanol Attn: S S & Co. United States of America

Fast Dissolving Orally 201, Tabor Road Morris Consumable Films Warner-Lambert Company Plains, New Jersey Filing Date: 27/04/2004 Warrant signed on 2200 containing Modified Starch LLC Wef: 02/05/2003 Vide PT 2200 07950, United States of Rec: 3565/6 dt 28/04/2004 16/09/2004 for Improved Heat and Attn: S S & Co. America Moisture Resistance

PDE9 Inhibitors for treating Eastern Point Road, type 2 Diabetes, Metabolic Pfizer Products Inc. Filing Date: 29/04/2004 Warrant signed on 2201 Groton, Connecticut Wef: 30/04/2003 Vide PT 2201 Syndrome and Attn: S S & Co. Rec: 3613/4 dt 30/04/2004 09/11/2004 06340, USA Cardiovascular Disease

P.O.Box 4000, Route 206 Aryl - Substituted Pyrazole- Bristol-Myers Squibb and Province Line Road, Filing Date: 01/05/2004 Warrant signed on 2202 Armide Derived Compounds Company Wef: 01/05/2003 Vide PT 2202 Princeton NJ08545-3000, Rec: 3715/6 dt 05/05/2004 23/11/2004 useful in Kinase Inhibitors Attn: S S & Co. United States of America

Piperidyl-and Piperazinyl- Alkylcarbamate Derivatives Sanofi - Aventis 174 Avenue de France, Filing Date: 05/05/2004 Warrant signed on 2203 Wef: 07/05/2003 Vide PT 2203 Preparations and Therapeutic Attn: S S & Co. FR-75013 Paris, France Rec: 3733/4 dt 05/05/2004 23/11/2004 Application Thereof

An Intermediate that can be Fructuos Gelabert 6-8, Medichem SA Filing Date: 07/05/2004 Warrant signed on 2204 used for the Preparation of Sant Joan Despi, 08970 Wef: 09/05/2003 Vide PT 2204 Attn: B&M Patentbureau Rec: 4125/6 dt 18/05/2004 23/11/2004 Pioglitazione Barcelona, Spain

Use of Sulphonamide Derivatives for the Laboratorios del Dr. Esteve Av. Mare de Deu de Manufacture of a medicament Filing Date: 07/05/2004 Wef: 09/05/2003 Warrant signed on 2205 SA Monsterrat, 221, E-08041 Vide PT 2205 for the Prophylaxis and for Rec: 4272/3 dt 24/05/2004 Wef: 28/07/2003 18/01/2005 Attn: CC Advocates Barcelona, Spain Treatment of Disorders of food Ingestion

235, East 42nd Street, Compounds useful for the Pfizer Inc. Filing Date: 12/05/2004 Wef: 15/05/2003 Warrant signed on 2206 New York, New York Vide PT 2206 treatment of Diseases Attn: S S & Co. Rec: 3952/3 dt 12/05/2004 Wef: 23/12/2003 23/11/2004 10017, USA

Filing Date: 12/05/2004 New Benzimidazole Astrazeneca AB SE-151 85 Sodertalje, Wef: 16/05/2003 Warrant signed on 2207 Rec: 3949/50 dt Vide PT 2207 Derivatives Attn: S S & Co. Sweden Wef: 12/01/2004 06/12/2004 12/05/2004 Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filind Date: 12/05/2004 Warrant signed on 2208 Derivatives Preparations Wef: 16/05/2003 Vide PT 2208 Attn: S S & Co. Sweden Rec: 3546/7 dt 12/05/2004 06/12/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 12/05/2004 Wef: 16/05/2003 Warrant signed on 2209 Derivatives Preparations Vide PT 2209 Attn: S S & Co. Sweden Rec: 3943/4 dt 12/05/2004 Wef: 09/01/2004 06/12/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 12/05/2004 Warrant signed on 2210 Derivatives Preparations Wef: 16/05/2003 Vide PT 2210 Attn: S S & Co. Sweden Rec: 5940/1 dt 12/05/2004 23/11/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 12/05/2004 Warrant signed on 2211 Derivatives Preparations Wef: 16/05/2003 Vide PT 2211 Attn: S S & Co. Sweden Rec: 3937/8 dt 12/05/2004 06/12/2004 thereof and uses thereof

Diarylmethylidene Piperidine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 12/05/2004 Warrant signed on 2212 Derivatives Preparations Wef: 16/05/2003 Vide PT 2212 Attn: S S & Co. Sweden Rec: 3934/5 dt 12/05/2004 06/12/2004 thereof and uses thereof

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 18/05/2004 Wef: 27/05/2003 Warrant signed on 2215 Novel Compounds Vide PT 2215 Attn: S S & Co. Sweden Rec: 4132/4 dt 18/05/2004 Wef: 27/08/2003 06/12/2004

Methods and Compositions Eastern Point Road, Filing Date: 18/05/2004 for Diagnosing and Treating Pfizer Products Inc. Warrant signed on 2216 Groton, Connecticut Rec: 4129/30 dt Wef: 18/05/2003 Vide PT 2216 Disorders Involving Attn: S S & Co. 06/12/2004 06340, USA 18/05/2004 Angiogenesis

Cyclic Sulfonamides for Merck Sharpe & Dohme Hertford Road, Filing Date: 17/05/2004 Warrant signed on 2217 Inhibition of Gamma Limited Hoddesdon, Hertfordshire Wef: 16/05/2003 Vide PT 2217 Rec: 4191/2 dt 20/05/2004 06/12/2004 Secretase Attn: CC Advocates EN119BU, UK

Carbostyril Derivatives and Otsuka Pharmaceutical Co 2-9 Karola Tsukasacho, Filing Date: 21/05/2004 Warrant signed on 2218 mood Stabilizers for Treating Ltd Chijoda -Ku, Tokyo, Wef: 23/05/2003 Vide PT 2218 Rec: 4371/2 dt 26/05/2004 06/12/2004 Mood Disorders Attn: S S & Co. Japan

Imido-Fused Oxazolo [4,5-B] Pyridine and Imidazo-Fused P.O. Box 4000, Route 206 Thiazole [4,5-B] Pyridine Bristol-Myers Squibb and Province Line Road, Filing Date: 21/05/2004 Warrant signed on 2219 Based Tricyclic Compounds Company Wef: 21/05/2003 Vide PT 2219 Princeton NJ08543-4000, Rec: 4374/5 dt 26/05/2004 06/12/2004 and Pharmaceutical Attn: S S & Co. USA Compositions Comprising Same Inhibitors of 11-Beta- Biovitrum AB SE-112- 76 Stockholm, Filing Date: 21/05/2004 Warrant signed on 2220 Hydroxy Steroid Wef: 21/05/2003 Vide PT 2220 Attn: S S & Co. Sweden Rec: 4364/6 dt 26/05/2004 06/12/2004 dehydrogenase Type1

2-Amino-Pyridine Derivatives 235, East 42nd Street, Pfizer Inc. Filing Date: 24/05/2004 Warrant signed on 2221 useful for the treatment of New York, New York Wef: 04/06/2003 Vide PT 2221 Attn: S S & Co. Rec: 4286/7 dt 24/05/2004 17/12/2004 Disease 10017, USA

Filing Date: 24/05/2004 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2222 Novel Compounds Rec: 4289/90 dt Wef: 04/06/2003 Vide PT 2222 Attn: S S & Co. Sweden 17/11/2004 24/05/2004

2-Amino-Pyridine Derivatives 235, East 42nd Street, Pfizer Inc. Filing Date: 26/05/2004 Warrant signed on 2223 useful for the Treatment of New York, New York Wef: 04/06/2003 Vide PT 2223 Attn: S S & Co. Rec: 4403/4 dt 26/05/2004 17/11/2004 Diseases 10017, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/05/2004 Wef: 02/06/2003 Warrant signed on 2224 Novel Compounds Vide PT 2224 Attn: S S & Co. Sweden Rec: 4400/1 dt 26/05/2004 Wef: 10/06/2003 22/02/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/05/2004 Wef: 29/05/2003 Warrant signed on 2225 New Combination Vide PT 2225 Attn: S S & Co. Sweden Rec: 4396/7 dt 26/05/2004 Wef: 05/06/2003 06/12/2004

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 26/05/2004 Warrant signed on 2226 Novel Compounds Wef: 05/06/2003 Vide PT 2226 Attn: S S & Co. Sweden Rec :4393/4 dt 26/05/2004 17/12/2004

Filing Date: 26/05/2004 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2228 Novel Compounds Rec: 4381/8 dt Wef: 05/06/2003 Vide PT 2228 Attn: S S & Co. Sweden 17/12/2004 26/05/2004

Methods and Compositions Eastern Point Road, for Diagnosing and Treating Pfizer Products Inc. Filing Date: 26/05/2004 Warrant signed on 2229 Groton, Connecticut Wef: 06/06/2003 Vide PT 2229 Disorders Involving Attn: S S & Co. Rec: 4384/5 dt 26/05/2004 17/12/2004 06340, USA Angiogenesis

Wef: 27/05/2003 Janssen Pharmaceutica N.V Turnhoutseweg 30, B- Filing Date: 26/05/2004 Warrant signed on 2230 Quinazoline Derivatives Wef: 15/09/2003 Vide PT 2230 Attn: EMD Advocates 2340 Beerse, Belgium Rec: 4380/1 dt 26/05/2004 06/12/2004 Wef: 18/12/2003

Eastern Point Road, Azithromycin Dosage forms Pfizer Products Inc. Filing Date: 27/05/2004 Wef: 04/12/2003 Warrant signed on 2231 Groton, Connecticut Vide PT 2231 with reduced side effects Attn: S S & Co. Rec: 4435/6 dt 27/05/2004 Wef: 23/01/2004 21/06/2005 06340, USA

Eastern Point Road, Beta-Lactamase Inhibitor Pfizer Products Inc. Filing Date: 01/06/2004 Wef: 05/06/2003 Warrant signed on 2232 Groton, Connecticut Vide PT 2232 Prodrug Attn: S S & Co. Rec: 4550/1 dt 01/06/2004 Wef: 27/08/2003 17/12/2004 06340, USA 1, 1-Disubstitutedcycloalkyl, Glycinamidyl Sulfonyl- Amidino, and P.O. Box 4000, Route 206 Bristol-Myers Squibb Tetrahydropyrimidinyl and Province Line Road, Filing Date: 08/06/2004 Warrant signed on 2233 Company Wef: 04/06/2003 Vide PT 2233 Containing Diaminoalkyl, B- Princeton NJ08543-4000, Rec: 4786/7 dt 11/06/2004 17/01/2004 Attn: S S & Co. Aminoacids, a -Aminoacids USA and Derivatives thereof as factor XA Inhibitors

Benzimidazole Derivatives Compositions Containing Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 08/06/2004 Warrant signed on 2234 Wef: 10/06/2003 Vide PT 2234 them, Preparation thereof Attn: S S & Co. Sweden Rec: 4765/6 dt 11/06/2004 17/12/2004 and Uses thereof

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 08/06/2004 Wef: 13/06/2003 Warrant signed on 2235 New Azetidine Compounds Vide PT 2235 Attn: S S & Co. Sweden Rec: 4768/9 dt 11/06/2004 Wef: 19/12/2003 17/12/2004

Benzimidazole Derivatives Compositions Containing Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 08/06/2004 Warrant signed on 2236 Wef: 10/06/2003 Vide PT 2236 them, Preparation thereof Attn: S S & Co. Sweden Rec: 4772/3 dt 11/06/2004 17/12/2004 and uses thereof

Eastern Point Road, Pfizer Products Inc. Filing Date: 08/06/2004 Wef: 17/06/2003 Warrant signed on 2237 Novel Compounds Groton, Connecticut Vide PT 2237 Attn: S S & Co. Rec: 4775/6 dt 11/06/2004 Wef: 06/08/2003 04/01/2005 06340, USA

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2238 Chemical Compounds Wef: 17/06/2003 Vide PT 2238 Attn: S S & Co. Sweden Rec: 4814/8 dt 11/06/2004 04/01/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2239 Therapeutic Agents Wef: 18/06/2003 Vide PT 2239 Attn: S S & Co. Sweden Rec: 4811/2 dt 11/06/2004 04/01/2005

Filing Date: 11/06/2004 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2240 Therapeutic Agents Rec: 4809/10 dt Wef: 18/06/2003 Vide PT 2240 Attn: S S & Co. Sweden 04/01/2005 11/06/2004

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2241 Therapeutic Agents Wef: 18/06/2003 Vide PT 2241 Attn: S S & Co. Sweden Rec: 4806/7 dt 11/06/2004 04/01/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2242 Therapeutic Agents Wef: 18/06/2003 Vide PT 2242 Attn: S S & Co. Sweden Rec: 4804/5 dt 11/06/2004 04/01/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2243 Therapeutic Agents Wef: 18/06/2003 Vide PT 2243 Attn: S S & Co. Sweden Rec: 4802/3 dt 11/06/2004 04/01/2005 Filing Date: 11/06/2004 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2244 Therapeutic Agents Rec: 4799/800 dt Wef: 18/06/2003 Vide PT 2244 Attn: S S & Co. Sweden 04/01/2005 11/06/2004

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2245 Therapeutic Agents Wef: 18/06/2003 Vide PT 2245 Attn: S S & Co. Sweden Rec: 4796/7 dt 11/06/2004 04/01/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 11/06/2004 Warrant signed on 2246 Therapeutic Agents Wef: 18/06/2003 Vide PT 2246 Attn: S S & Co. Sweden Rec: 4794/5 dt 11/06/2004 04/01/2005

P.O. Box 4000, Route 206 N-Ureidoalkyl - Piperidines as Bristol Myers Squibb and Province Line Road, Filing Date: 11/06/2004 Warrant signed on 2247 Modulators of chemokine Company Wef: 12/06/2003 Vide PT 2247 Princeton, New Jersey Rec: 4791/2 dt 11/06/2004 17/12/2004 Receptor Activity Attn: S S & Co. 08543 4000, USA

Prinzregentenstrasse Ultrasound Contrast Agent Giesecke & Devrient GmbH Filing date: 11/06/2004 Warrant signed on: 2248 159, 81677 Munich, Wef: 12/06/2003 Vide PT 2248 Dosage Formulation Att: B&M Patentbureau Rec: 4886/7 dt 14/06/2004 17/12/2004 Germany

Glaxo Wellcore House, Glaxo Group Limited, Berkeley Avenue, Filing Date: 14/06/2004 Warrant signed on 2250 Pharmaceutical Formulations Wef: 16/06/2003 Vide PT 2250 Attn: S S & Co. Greenford Middlesex 4B6 Rec: 5064/5 dt 18/06/2004 04/01/2005 0NN, Great Britain

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 14/06/2004 Warrant signed on 2251 Therapeutic Agents Wef: 18/06/2003 Vide PT 2251 Attn: S S & Co. Sweden Rec: 5072/3 dt 18/06/2004 04/01/2005

Use of Substituted chromans Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 14/06/2004 Warrant signed on 2252 for Thiocromans for the Wef: 19/06/2003 Vide PT 2252 Attn: S S & Co. Sweden Rec: 5075/6 dt 18/06/2004 04/01/2005 Treatment of IBS

Use of Substituted Chromans Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 14/06/2004 Warrant signed on 2253 or thiocromans for the Wef: 19/06/2003 Vide PT 2253 Attn: S S & Co. Sweden Rec: 5078/9 dt 18/06/2004 04/01/2005 Treatment of FGD

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 14/06/2004 Warrant signed on 2254 Therapeutic Agents Wef: 19/06/2003 Vide PT 2254 Attn: S S & Co. Sweden Rec: 5081/2 dt 18/06/2004 04/01/2005

One Amgen Centre Drive, Piperazine Derivatives and Amgen Inc. Thousand Oaks, Filing Date: 14/06/2004 Warrant signed on 2255 Wef: 20/06/2003 Vide PT 2255 Methods of use Attn: CC Advocates California 91320-1799, Rec: 5057/8 dt 18/06/2004 04/01/2005 USA GlaxoSmithKline Biologicals Filing Date: 15/06/2004 Rue de L'Institute 89, B- Warrant signed on 2256 Vaccine Compositions S.A Rec: 5059/60 dt Wef: 16/06/2003 Vide PT 2256 1330 Rixensart, Belgium 04/01/2005 Attn: S S & Co. 18/06/2004

Compositions and Methods 1631 220th Street SE, Celltech R&D Inc. Filing Date: 16/06/2004 Warrant signed on 2258 for Increasing Bone Bothell, WA 98021, Wef: 16/06/2003 Vide PT 2258 Attn: MAMO TCV Advocates Rec: 5048/9 dt 18/06/2004 04/01/2005 Mineralization United States of America

Antibodies Specific for 1631 220th Street SE, Sclerostin and Methods for Celltech R&D Inc. Filing Date: 16/06/2004 Warrant signed on 2259 Bothell, WA 98021, Wef: 16/06/2003 Vide PT 2259 Increasing Bone Attn: MAMO TCV Advocates Rec: 5044/5 dt 18/06/2004 04/01/2005 United States of America Mineralization

Glaxo Wellcome House, Filing Date: 17/06/2004 Glaxo Group Ltd Berkeley Avenue, Warrant signed on 2260 Chemical Compounds Rec: 5029/30 dt Wef: 19/06/2003 Vide PT 2260 Attn: S S & Co. Greenford Middlesex 4B6 17/12/2004 18/06/2004 0NN, Great Britain

Metronidazole- Based Tinted Galderma Research & 635 Route des Lucioles, Filing Date: 17/06/2004 Warrant signed on 2261 Topical Pharmaceutical Development S.N.C. BP87, 06902 Sophia Wef: 18/06/2003 Vide PT 2261 Rec: 5032/4 dt 18/06/2004 04/01/2005 Composition Attn: S S & Co. Antipolis Cedex, France

Novel Compounds that Modulate ppary Type Galderma Research & 635 Route des Lucioles, Receptors and uses thereof Filing Date: 17/06/2004 Warrant signed on 2262 Development S.N.C. BP87, 06902 Sophia Wef: 20/06/2003 Vide PT 2262 in Cosmetic or Rec: 5035/6 dt 18/06/2004 04/01/2005 Attn: S S & Co. Antipolis Cedex, France Pharmaceutical Compositions

4-(Aminomethyl)-Piperidine Jassen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 17/06/2004 Warrant signed on 2263 Benzamides as 5HT4 - Wef: 19/06/2003 Vide PT 2263 Attn: EMD Advocates 2340 Beerse, Belgium Rec: 5026/7 dt 18/06/2004 12/01/2005 Antaogonists

Novel Imidazopyridine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 21/06/2004 Warrant signed on 2264 Compound III with Wef: 26/06/2003 Vide PT 2264 Attn: S S & Co. Sweden Rec: 5145/6 dt 21/06/2004 04/01/2005 Therapeutic Affect

Novel Imidazopyridine Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 21/06/2004 Warrant signed on 2265 Compound II with Wef: 26/06/2003 Vide PT 2265 Attn: S S & Co. Sweden Rec: 5147/8 dt 21/06/2004 04/01/04 Therapeutic Affect

Novel Imidazopyridine Filing Date: 21/06/2004 Astrazeneca AB SE-151 85 Sodertalje, Warrant signed on 2266 Compound I with Therapeutic Rec: 5149/50 dt Wef: 26/06/2003 Vide PT 2266 Attn: S S & Co. Sweden 04/01/2005 Affect 21/06/2004

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 21/06/2004 Warrant signed on 2267 Novel Compounds Wef: 27/06/2003 Vide PT 2267 Attn: S S & Co. Sweden Rec: 5151/2 dt 21/06/2004 04/01/2005 Glaxo Wellcome House, Glaxo Group Limited, Berkeley Avenue, Filing Date: 22/06/2004 Warrant signed on 2268 Novel Compositions Wef: 24/06/2003 Vide PT 2268 Attn: S S & Co. Greenford Middlesex 4B6 Rec: 5216/7 dt 22/06/2004 04/01/2005 0NN, Great Britain

Compositions in the form of a Spray Comprising a Galderma Research & 635 Route des Lucioles, Filing Date: 22/06/2004 Warrant signed on 2269 Pharmaceutical Active Agent Development S.N.C. BP87, 06902 Sophia Wef: 23/06/2003 Vide PT 2269 Rec: 5218/9 dt 22/06/2004 04/01/2005 at least one Volatile Silicone Attn: S S & Co. Antipolis Cedex, France and a nonvolatile

4-Cyanopyrazole-3- Carboaxamide Derivatives, Sanofi - Aventis 174 Avenue de France, Filing Date: 24/06/2004 Warrant signed on 2270 Wef: 25/06/2003 Vide PT 2270 their Preparation, their Attn: S S & Co. FR-75013 Paris, France Rec: 5290/1 dt 24/06/2004 04/01/2005 Therapeutic Application

Diphenylpyridine Derivatives Preparation thereof and Sanofi - Aventis 174 Avenue de France, Filing Date: 24/06/2004 Warrant signed on 2271 Wef: 26/06/2003 Vide PT 2271 Aplication thereof in Attn: S S & Co. FR-75013 Paris, France Rec: 5292/3 dt 24/06/2004 04/01/2005 Therapeutics

One Amgen Centre Drive, Substituted Heterocyclic Amgen Inc. Thousand Oaks, Filing Date: 24/06/2004 Warrant signed on 2273 Compounds and Methods of Wef: 24/06/2003 Vide PT 2273 Attn: CC Advocates California 91320-1799, Rec: 5346/7 dt 30/06/2004 18/01/2004 use USA

P.O. Box 4000, Route 206 Indole, Azaindole and related Bristol-Myers Squibb and Province Road, Filing Date: 01/07/2004 Wef: 01/07/2003 Warrant signed on 2274 Heterocyclic N-Substituted Company Princeton, New Jersey Rec: 5489/90 dt Wef: 07/08/2003 Vide PT 2274 18/01/2005 Piperazine Derivatives Attn: S S & Co. 08543-4000, United 05/07/2004 Wef: 05/02/2004 States of America

Combination of SRC Kinase P.O. Box 4000, Route 206 Inhibitors & Bristol-Myers Squibb and Province Road, Filing Date: 05/07/2004 Warrant signed on 2275 Chemotherapeutic Agents for Company Princeton, New Jersey Wef: 09/07/2003 Vide PT 2275 Rec: 5500/1 dt 05/07/2004 18/01/2005 the Treatments of Attn: S S & Co. 08543-4000, United Proliferative Diseases States of America

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 05/07/2004 Warrant signed on 2276 Therapeutic Agents Wef: 11/07/2003 Vide PT 2276 Attn: S S & Co. Sweden Rec: 5503/4 dt 05/07/2004 18/01/2005

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 05/07/2004 Warrant signed on 2277 Therapeutic Agents Wef: 11/07/2003 Vide PT 2277 Attn: S S & Co. Sweden Rec: 5506/7 dt 05/07/2004 09/02/2005 Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 05/07/2004 Isethionate Salt of a Selective Warrant signed on 2278 LLC Plains, New Jersey Rec: 5509/10 dt Wef: 11/07/2003 Vide PT 2278 CDK4 Inhibitor 18/01/2005 Attn: S S & Co. 07950, USA 05/07/2004

Astrazeneca AB SE-151 85 Sodertalje, Filing Date: 05/07/2004 Warrant signed on 2279 New Compounds Wef: 08/07/2003 Vide PT 2279 Attn: S S & Co. Sweden Rec: 5512/3 dt 05/07/2004 18/01/2005

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 06/07/2004 Warrant signed on 2282 Pharmaceutical Formulation Wef: 10/07/2003 Vide PT 2282 Attn: S S & Co. Greenford Middlesex Rec: 5561/2 dt 06/07/2004 09/02/2005 4B60 NN, Great Britain

Glaxo Wellcome House, Filing Date: 09/07/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2284 Novel Compounds Rec: 5679/80 dt Wef: 11/07/2003 Vide PT 2284 Attn: S S & Co. Greenford Middlesex 18/01/2005 09/07/2004 4B60 NN, Great Britain

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 09/07/2004 Warrant signed on 2285 Novel Compounds Wef: 11/07/2003 Vide PT 2285 Attn: S S & Co. Greenford Middlesex Rec: 5682/3 dt 09/07/2004 18/01/2005 4B60 NN, Great Britain

Pyrrolo [3,4-C] Pyrazole Derivatives Active as Kinase Inhibitors, Processes for their Pharmacia Italia SPA Via Robert Koch 12, 1- Filing Date: 09/07/2004 Warrant signed on 2286 Preparation and Wef: 09/07/2003 Vide PT 2286 Att: S S & Co. 20152 Milano, Italy Rec: 5684/5 dt 09/07/2004 18/01/2005 Pharmaceutical Compositions Comprising them

Astrazeneca AB SE- 151 85 Sodertalje, Filing Date: 13/07/2004 Warrant signed on 2287 Chemical Compounds Wef: 16/07/2003 Vide PT 2287 Att: S S & Co. Sweden Rec: 5797/8 dt 13/07/2004 15/03/2005

Triazolopyrimidine Janssen Pharmaceutica N.V Turnhoutseweg 30, B- Filing Date: 14/07/2004 Warrant signed on 2288 Derivatives as Glycogen Wef: 16/07/2003 Vide PT 2288 Att: EMD Advocates 2340 Beerse, Belgium Rec: 5843/4 dt 14/07/2004 09/02/2005 Sunthase Kinase 3 Inhibitors

Triazolopyrimidine Janssen Pharmaceutica N.V Turnhoutseweg 30, B- Filing Date: 14/07/2004 Warrant signed on 2289 derivatives as glycogen Wef: 16/06/2003 Vide PT 2289 Att: EMD Advocates 2340 Beerse, Belgium Rec: 5846/7 dt 14/07/2004 09/02/2005 synthase kinase 3 inhibitors Glaxo Wellcome House, Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Filing Date: 15/07/2004 Warrant signed on 2290 Wef: 17/07/2003 Vide PT 2290 receptor antagonists Attn: S S & Co. Greenford Middlesex Rec: 5871/2 dt 15/07/2004 09/02/2005 4B60 NN, Great Britain

Glaxo Wellcome House, Filing Date: 15/07/2004 Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Warrant signed on 2291 Rec: 5874/5 dt 15/07/2004 Wef: 17/07/2003 Vide PT 2291 receptor antagonists Attn: S S & Co. Greenford Middlesex 09/02/2005 4B60 NN, Great Britain

Glaxo Wellcome House, Muscarinic Acetycholine Glaxo Group Limited Berkeley Avenue, Filing Date: 15/07/2004 Warrant signed on 2292 Wef: 17/07/2003 Vide PT 2292 Receptor Antagonists Attn: S S & Co. Greenford Middlesex Rec: 5877/8 dt 15/07/2004 09/02/2005 4B60 NN, Great Britain

One Amgen Centre Drive, Thousand Oaks, Human Anti-NGF Neutralizing Filing Date: 15/07/2004 Amgen Inc. & Medarex Inc. California 91320-1799, Warrant signed on 2293 Antibodies as Selective NGF Rec: 5895/6 dt 16/07/2004 Wef: 15/07/2003 Vide PT 2293 Attn: B&M Patentbureau USA & 707, State Road, 18/02/2005 Pathway Inhibitors Princeton, New Jersey 08540, USA

One Amgen Centre Drive, Thousand Oaks, Specific Binding Agents to Amgen Inc. & Abgenix Inc. California 91320-1799, Filing Date: 16/07/2004 Warrant signed on 2295 Wef: 18/07/2003 Vide PT 2295 Hepatocyte Growth Factor Att: B&M Patentbureau USA & 6701 Kaiser Drive Rec: 5898/9 dt 16/07/2004 09/02/2005 Fremont, California 94555, USA

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 16/07/2004 Warrant signed on 2296 Novel Compounds Wef: 16/07/2004 Vide PT 2296 Attn: S S & Co. Greenford Middlesex Rec: 5905/6 dt 16/07/2004 09/02/2005 4B60 NN, Great Britain

Glaxo Wellcome House, Quinoline & Quinazoline Glaxo Group Limited Berkeley Avenue, Filing Date: 16/07/2004 Warrant signed on 2297 Derivatives having Affinity for Wef: 18/07/2003 Vide PT 2297 Attn: S S & Co. Greenford Middlesex Rec: 5908/9 dt 16/07/2004 09/02/2005 5HT1-Type Receptors 4B60 NN, Great Britain

235 East 42nd Street, Pfizer Inc. New York, New York Filing Date: 21/07/2004 Warrant signed on 2298 Compounds Wef: 25/07/2003 Vide PT 2298 Att: S S & Co. 10017, United State of Rec: 5932/3 dt 22/07/2004 09/02/2005 America 235 East 42nd Street, Pfizer Inc. New York, New York Filing Date: 21/07/2004 Warrant signed on 2299 Compounds Wef: 25/07/2003 Vide PT 2299 Att: S S & Co. 10017, United State of Rec: 5935/6 dt 22/07/2004 09/02/2005 America

Astrazeneca AB SE- 151 85 Sodertalje, Filing Date: 21/07/2004 Wef: 29/07/2003 Warrant signed on 2300 Quinazoline Derivatives Vide PT 2300 Att: S S & Co. Sweden Rec: 5938/9 dt 22/07/2004 Wef: 01/06/2003 09/02/2005 MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

980 Great West Road, Smithkline Beecham plc Filing Date: 21/07/2004 Warrant signed on 2301 Pharmaceutical Formulations Brentford, Middlesex TW8 Wef: 21/07/2003 Vide PT 2301 Att: SS & Co. Rec: 5941/2 dt 22/07/2004 09/02/2005 9 GS, United Kingdom

One Amgen Center Drive, Compositions and Methods Immunex Corporation Filing Date: 22/07/2004 Warrant signed on 2302 Thousand Oaks, California Wef: 22/07/2003 Vide PT 2302 relating to TSP-30 a,b,c and d Att: MAMO TCV Rec: 5968/9 dt 22/07/2004 09/02/2005 91320-1799, USA

Substituted Heterocylic One Amgen Center Drive, Amgen Inc Filing Date: 22/07/2004 Wef: 24/07/2003 Warrant signed on 2303 Compounds and Methods of Thousand Oaks, California Vide PT 2303 Att: Dr M. Chetcuti Cauchi Rec: 5973/4 dt 22/07/2004 Wef: 13/07/2004 09/02/2005 use 91320-1799, USA

Substituted Heterocylic One Amgen Center Drive, Amgen Inc Filing Date: 22/07/2004 Warrant signed on 2304 Compounds and Methods of Thousand Oaks, California Wef: 25/07/2003 Vide PT 2304 Att: Dr M. Chetcuti Cauchi Rec: 5976/7dt 22/07/2004 09/02/2005 use 91320-1799, USA

One Amgen Center Drive, Amgen Inc Filing Date: 22/07/2004 Warrant signed on 2305 Process for purifying proteins. Thousand Oaks, California Wef: 30/01/2004 Vide PT 2305 Att: Dr M. Chetcuti Cauchi Rec: 5980/1 dt 22/07/2004 01/08/2006 91320-1799, USA

One Amgen Center Drive, Short interfering RNA as an Amgen Inc Filing Date: 23/07/2004 Wef: 25/07/2003 Wef: Warrant signed on 2306 Thousand Oaks, California Vide PT 2306 antiviral agent for hepatitis C Att: Dr M. Chetcuti Cauchi Rec: 6160/1 dt 05/08/2004 22/07/2004 21/02/2005 91320-1799, USA

Compositions and Methods One Amgen Center Drive, Filing Date: 23/7/2004 relating to Multimeric and Amgen Inc. Warrant signed on 2307 Thousand Oaks, California Rec: 6009/10 dt Wef: 24/07/2003 Vide PT 2307 Oligomeric soluble fragments Att. MAMO TCV Advocates 09/02/2005 91320-1799, USA 27/07/2004 of the tweak receptor.

One Amgen Center Drive, Antagonists and agonists of Amgen Inc Filing Date: 26/07/2003 Warrant signed on 2308 Thousand Oaks, California Wef: 25/07/2003 Vide PT 2308 LDCAM and Methods of use. Att. SS & Co Rec: 6014/5 dt 27/07/2004 09/02/2005 91320-1799, USA

3, 5 disubstituted indazole compounds, pharmaceutcial 235 East 42nd Street, Pfizer Inc. Filing Date: 27/07/2004 Wef: 30/07/2003 Warrant signed on 2310 compositions, and Methods New York , New York Vide PT 2310 Att: SS & Co. Rec: 6030/1 dt 27/07/2004 Wef: 31/07/2003 09/02/2005 for mediating or inhibiting cell 10017, USA proliferation. Pharmacia & Upjohn 301, Henrietta Street Dispersible formulation of an Filing Date: 27/07/2004 Warrant signed on 2311 Company Kalamazoo, Michigan Wef: 31/07/2003 Vide PT 2311 anti-inflammatory agent Rec: 6026/7 dt 27/07/2004 09/02/2005 Att: SS & Co. 49001, USA

Dispersable pharmaceutical Pharmacia & Upjohn 301, Henrietta Street Filing Date: 27/07/2004 Warrant signed on 2312 composition for treatment of Company Kalamazoo, Michigan Wef: 31/07/2003 Vide PT 2312 Rec: 6023/4 dt 27/07/2004 09/02/2005 mastitis and otic disorders. Att: SS & Co. 49001, USA

Astrazeneca AB SE - 15185 Sodertalje Filing Date: 27/07/2004 Wef: 31/07/2003 Warrant signed on 2313 Chemical compounds Vide PT 2313 Att: SS & Co. , Sweden Rec: 6020/1 dt 27/07/2004 Wef: 03/06/2004 09/02/2005

Smithkline Beecham One Franklin Plaza Filing Date: 27/07/2004 Warrant signed on 2314 Inhibitors of AKT activity Corporation PO Box 7929 Philadelphia Wef: 29/07/2003 Vide PT 2314 Rec: 6017/8 dt 27/7/2004 02/03/2005 Att: SS & CO. Pennsylvania 10101 USA

PO BOX 4000, Route 206 Adamantyglycine-based Bristol-Myers Squibb and Province Line Rd, Filing Date: 27/07/2004 Warrant signed on 2316 inhibitors of depeptidyl Company Wef: 01/08/2003 Vide PT 2316 Princeton, New Jersey, Rec: 6044/5 dt 27/07/2004 21/02/2005 peptidase IV Methods. Att: MAMO TCV Advocates USA

Benzoxazinone-derived Laboratorios del Dr. AV. Mare de Deu de sulphonamide compounds, Filing Date: 29/07/2004 Warrant signed on 2317 ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2317 their preparation and their use Rec: 6086/7 dt 29/07/2004 02/03/2005 Att: B&M Patentbureau Barcelona, Spain in medicaments.

1,4 - Disubstituted piperidine Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2318 compounds, their preparation ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2318 Rec: 6083/4 dt 29/07/2004 02/03/2005 and use as medicaments. Att: B&M Patentbureau Barcelona, Spain

Active Substance Combination comprising A 2, 5 - Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2319 Dihydroxybenzenesulfonic ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2319 Rec: 6080/1 dt 29/07/2004 02/03/2005 compound and a potassium Att: B&M Patentbureau Barcelona, Spain channel modulator

Indol - 6 -Yl Sulfonamide Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2320 derivatives, their preparation ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2320 Rec: 6077/8 dt 29/07/2004 11/04/2005 and their use in medicaments. Att: B&M Patentbureau Barcelona, Spain

Indol - 5 -Yl Sulfonamide Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2321 derivatives, their preparation ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2321 Rec: 6074/5 dt 29/07/2004 02/03/2005 and their use in medicaments. Att: B&M Patentbureau Barcelona, Spain Indol - 4 -Yl Sulfonamide Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2322 derivatives, their preparation ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2322 Rec: 6071/2 dt 29/07/2004 02/03/2005 and their use in medicaments. Att: B&M Patentbureau Barcelona, Spain

Indol - 7 -Yl Sulfonamide Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2323 derivatives, their preparation ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 23/07/2003 Vide PT 2323 Rec: 6068/9 dt 29/07/2004 02/03/2005 and their use in medicaments. Att: B&M Patentbureau Barcelona, Spain

1- Sulfonylindole derivatives, Laboratorios del Dr. AV. Mare de Deu de Filing Date: 29/07/2004 Warrant signed on 2324 their preapration and their use ESTEVE S.A. Montserrat, 221, E - 08041 Wef: 30/07/2003 Vide PT 2324 Rec: 6065/6 dt 29/07/2004 02/03/2005 in medicaments. Att: B&M Patentbureau Barcelona, Spain

Resolution Chemicals Wolfwood Way, Production of delta 9 Filing Date: 29/07/2004 Warrant signed on 2325 Limited Stevenage, Herts SG 1 Wef: N/A Vide PT 2325 tetrahyrocannabinol Rec: 6095/6 dt 30/07/2004 09/02/2005 Att: SS & Co. 4QT, Great Britain

Sanofi-Aventis 174 Avenue de France, F- Filing Date: 29/07/2004 Warrant signed on 2326 New Compounds Wef: 31/07/2003 Vide PT 2326 Att: S S & Co. 75013 Paris, France Rec: 6098/9 dt 30/07/2004 09/02/2005

Dipharma SpA. A process for the preparation Via XXV Maggio 40, Filing Date: 30/07/2004 Wef: 08/08/2003 Warrant signed on 2327 Att: Emmanuel Mallia & Vide PT 2327 of phenyltetrazole derivatives Mereto di Tomba, Italy Rec: 6114/5 dt 30/07/2004 Wef: 07/05/2004 21/02/2005 Associates

One Amgen Center Drive, Amgen Inc. Filing Date: 30/07/2004 Warrant signed on 2328 Crystalline polypeptides Thousand Oaks, California Wef: 01/08/2003 Vide PT 2328 Att. MAMO TCV Advocates Rec: 6154/5 dt 02/08/2004 21/02/2005 91320-1799, USA

6 - Membered heteroaryl Eastern Point Road, compounds for the treatment Pfizer Products Inc. Filing Date: 02/08/2004 Warrant signed on 2329 Groton, Connecticut Wef: 01/08/2003 Vide PT 2329 of neurodegenerative Att: SS & Co. Rec: 6163/4 dt 05/08/2004 21/02/2005 06340, USA disorders.

Filing Date: 03/08/2004 Process for the preparation of Zambon Group S.p.A. Via della Chimica, 9, 2330 Rec: 6166/7 dt Wef: 08/08/2003 WITHDRAWN Vide PT 2330 Gabapentin Att: SS & Co. 36100 - Vicenza, Italy 06/08/2004

Filing Date: 03/08/2004 Process for the preparation of Zambon Group S.p.A. Via della Chimica, 9, 2331 Rec: 6169/70 dt Wef: 08/08/2003 WITHDRAWN Vide PT 2331 Gabapentin Att: SS & Co. 36100 - Vicenza, Italy 05/08/2004

Pharmacia & UpJohn 301 Henrietta Street, Novel Anthelmintic and Filing Date: 03/08/2004 Warrant signed on 2332 Company Kalamazoo, Michigan Wef: 07/08/2003 Vide PT 2332 Insecticidal Compositions Rec: 6172/3 dt 05/08/2004 21/02/2005 Attn: S S & Co. 49001, U.S.A. GlaxoSmithkline Rue de L'Istitut 89, D-1330 Filing Date: 03/08/2004 Warrant signed on 2333 Novel Device Biologicals s.a. Wef: 04/08/2003 Vide PT 2333 Rixensart, Belgium Rec: 6175/6 dt 05/08/2004 21/02/2005 Att: SS & Co

Eastern Point Groton, Pfizer Products Inc. & Connecticut 06340, U.S.A. Filing Date: 03/08/2004 Warrant signed on 2334 Antibodies To GMet Abgenix Inc. & 6701 Kaiser Drive, Wef: 04/08/2004 Vide PT 2334 Rec: 6178/9 dt 05/08/2004 21/02/2005 Att: SS & Co. Fremont, California 94555, United States of America

PO Box 4000, Route 206 Cyclic Derivatives as Bristol-Myers Squibb and Province Line Road, Filing Date: 05/08/2004 Warrant signed on 2335 modulators of chemokine Company Wef: 21/08/2003 Vide PT 2335 Princeton, New Jersey, Rec: 6194/5 dt 05/08/2004 02/03/2005 receptor activity. Att: MAMO TCV Advocates USA

235 East 42nd Street New Wef: 14/08/2003 Pfizer Inc. Filing Date: 06/08/2004 Warrant signed on 2337 Piperazine derivatives York, New York Wef: 22/09/2003 Wef: Vide PT 2337 Att: SS & Co. Rec: 6342/3 dt 10/08/2004 21/02/2005 10017, USA 24/03/2004

Eastern Point Road, Modified human IGF- IR Pfizer Products Inc. Filing Date: 06/08/2004 Warrant signed on 2338 Groton, Connecticut Wef: 13/08/2003 Vide PT 2338 antibodies. Att: SS & Co. Rec: 6346/7 dt 10/08/2004 21/02/2005 06340, USA

235 East 42nd Street New Filing Date: 06/08/2004 Pfizer Inc. Wef: 14/08/2003 Wef: Warrant signed on 2339 Azaquinazoline derivatives York, New York Rec: 6349/50 dt Vide PT 2339 Att: SS & Co. 16/03/2004 21/02/2005 10017, USA 10/08/2004

BBV Tower, 8th Floor, 254 SB Pharmaco Puerto Rico Munoz Riveron Avenue, Filing Date: 06/08/2004 Warrant signed on 2340 Novel Composition Inc. Wef: 07/08/2003 Vide PT 2340 San Juan, Puerto Rico Rec: 6352/3 dt 10/08/2004 21/02/2005 Att: SS & CO. 00918

Oxazole Compounds for the Eastern Point Road, Pfizer Products Inc. Filing Date: 06/08/2004 Wef: 06/08/2003 Warrant signed on 2341 treatment of Groton, Connecticut Vide PT 2341 Att: SS & Co. Rec: 6355/6 dt 10/08/2004 Wef: 27/08/2003 21/02/2005 neurodegenerative disorders 06340, USA

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 10/08/2004 Warrant signed on 2342 Novel Compounds Wef: 10/08/2004 Vide PT 2342 Att: SS & Co. Sweden Rec: 6360/2 dt 10/08/2004 02/03/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 10/08/2004 Wef: 21/08/2003 Warrant signed on 2343 Novel Compounds Vide PT 2343 Att: SS & Co. Sweden Rec: 6304/5 dt 10/08/2004 Wef: 04/06/2004 02/03/2005

Pyrido [3,4-D)] pyrimidine Warner-Lambert Company 201 Tabor Road, Morris derivatives as matrix Filing Date: 10/08/2004 Warrant signed on 2344 LLC Plains, New Jersey 07950, Wef: 19/08/2003 Vide PT 2344 metalloproteinase-13 Rec: 6367/8 dt 10/08/2004 02/03/2005 Att: SS & Co. USA inhibitors 126 East Lincoln Avenue, Wef: 15/08/2003 Merck & Co Inc. Filing Date: 10/08/2004 Warrant signed on 2345 Mitotic Kinesin inhibitors. Railway, New Jersey Wef: 20/10/2003 Wef: Vide PT 2345 Att: SS & Co. Rec: 6370/1 dt 10/08/2004 02/03/2005 07065 - 0907, USA 19/04/2004

BBV Tower, 8th Floor, 254 SB Pharmaco Puerto Rico Munoz Riveron Avenue, Filing Date: 10/08/2004 Warrant signed on 2346 Novel Composition Inc. Wef: 11/08/2004 Vide PT 2346 San Juan, Puerto Rico Rec: 6461/2 dt 12/08/2004 21/02/2005 Att: SS & CO. 00918

27 'Genesis', Leli Camilleri Mr Charles S. White Filing date: 11/08/2004 Warrant signed on: 2347 Hydraulic-Leverage Plant Street, Zurrieq ZRQ 06, Wef: N/A Vide PT 2347 Att: N/A Rec: 6427/8 dt 11/08/2004 21/02/2005 Malta

EP4 Receptor agonist, 16711 Trares-Canada Merck Frosst Canada & Co. Filing Date: 12/08/2004 Warrant signed on 2348 compositions and methods Highway, Kirkland, Quebec Wef: N/A Vide PT 2348 Att: SS & Co. Rec: 6577/8 dt 13/08/2004 24/02/2006 thereof. H9H 3LI, Canada

126 East Lincoln Avenue, Filing Date: 12/08/2004 Biaryl substituted triazoles as Merck & Co Inc. Warrant signed on 2349 Railway, New Jersey Rec: 6579/80 dt Wef: N/A Vide PT 2349 sodium channel blockers Att: SS & Co. 24/02/2006 07065, USA 13/08/2004

N - Substituted nonaryl- 126 East Lincoln Avenue, Merck & Co Inc. Filing Date: 12/08/2004 Warrant signed on 2350 heterocyclic NM2A/NR 2B Railway, New Jersey Wef: N/A Vide PT 2350 Att: SS & Co. Rec: 6583/4 dt 13/08/2004 24/02/2006 antagonists. 07065, USA

126 East Lincoln Avenue, Merck & Co Inc. Filing Date: 12/08/2004 Warrant signed on 2351 CGRP receptor antagonists. Railway, New Jersey Wef: N/A Vide PT 2351 Att: SS & Co. Rec: 6586/7 dt 13/08/2004 24/02/2006 07065, USA

Nitric oxide releasing 16711 Trares-Canada prodrugs of diaryl - 2- (5H) Merck Frosst Canada & Co. Filing Date: 12/08/2004 Warrant signed on 2352 Highway, Kirkland, Quebec Wef: N/A Vide PT 2352 furanones as cyclooxygenase Att: SS & Co. Rec: 6588/9 dt 13/08/2004 24/02/2006 H9H 3LI, Canada 2 inhibitors.

16711 Trans-Canada Highway, Kirkland Quebec Method of treating Merck & Co, Inc & Merck H9H 3LI, Canada & Suite atherosclerosis dyslipidemias Filing Date: 12/08/2004 Warrant signed on 2353 Frosst Canada 900, 1959 Upper Water Wef: N/A Vide PT 2353 and related conditions and Rec: 6591/2 dt 13/08/2004 24/02/2006 Attn: S S & Co. Street, Halifax P.O. Box pharmaceutical compositions 997, Nova Scotia B3J 2X2, Canada

Phosphoric acid salt of a 126 East Lincoln Avenue, Merck & Co Inc. Filing Date: 12/08/2004 Warrant signed on 2354 dipeptidyl peptidase - IV Railway, New Jersey Wef: N/A Vide PT 2354 Att: SS & Co. Rec: 6593/4 dt 13/08/2004 01/03/2006 inhibitor. 07065, USA Acylated piperazine 126 East Lincoln Avenue, Merck & Co Inc. Filing Date: 12/08/2004 Warrant signed on 2355 derivatives as melanocortin - 4 Railway, New Jersey Wef: N/A Vide PT 2355 Att: SS & Co. Rec: 6596/7 dt 13/08/2004 24/02/2006 receptor agonists 07065, USA

One Amgen Center Drive, Melanin concentrating Amgen Inc. Filing Date: 12/08/2004 Warrant signed on 2356 Thousand Oaks, Wef: 13/08/2003 Vide PT 2356 hormone receptor antagonist Att: MAMO TCV Advocates Rec: 6506/7 dt 12/08/2004 21/02/2005 California, USA

Melanin concentrating One Amgen Center Drive, Amgen Inc. Filing Date: 12/08/2004 Warrant signed on 2357 hormone receptor Thousand Oaks, Wef: 13/08/2003 Vide PT 2357 Att: MAMO TCV Advocates Rec: 6503/4 dt 12/08/2004 21/02/2005 antagonists. California, USA

Substituted thiophenes and Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 13/08/2004 Wef: 15/08/2003 Warrant signed on 2359 Vide PT 2359 uses thereof Att: SS & CO. Sweden Rec: 6564/5 dt 13/08/2004 Wef: 28/05/2004 21/02/2005

700 Chesterfield, Parkway Pharmacia Corporation West, Chesterfield, Filing Date: 12/08/2004 Warrant signed on 2360 Substituted pyridinones. Wef: 13/08/2003 Vide PT 2360 Att: SS & Co. Missouri 63017- Rec: 6561/2 dt 13/08/2004 21/02/2005 1732, USA

PO Box 4000, Route 206 Bristol-Myers Squibb Pryazine modulators of and Province Line Road, Filing Date: 13/08/2004 Warrant signed on 2361 Company Wef: 15/08/2003 Vide PT 2361 cannabinoid receptors Princeton, New Jersey, Rec: 6572/3 dt 13/08/2004 21/02/2005 Att: MAMO TCV Advocates USA

4-Cycloalkylaminopyrazolo 126 East Lincoln Avenue, Filing Date: 17/08/2004 Merck & Co Inc. Warrant signed on 2362 pyrimidine nmda / nr 2B Railway, New Jersey Rec: 6699/700 dt Wef: N/A Vide PT 2362 Att: SS & Co. 28/02/2006 antagonists. 07065, USA 23/08/2004

Substituted heterocyclic One Amgen Center Drive, Filing Date: 17/08/2004 Amgen Inc. Warrant signed on 2363 compounds and methods of Thousand Oaks, Rec: P585309 dt Wef: 20/08/2003 Vide PT 2363 Att: CC Advocates 02/03/2005 use. California, USA 17/08/2004

SmithKline Beecham (Cork) Curraghbinny, Carrigaline, Filing Date: 19/08/2004 Warrant signed on 2365 Novel formulation. Limited Wef: 22/08/2003 Vide PT 2365 County Cork, Eierre Rec: 6824/5 dt 25/08/2004 02/03/2005 Att: SS & Co

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 19/08/2004 Warrant signed on 2366 Chemical Compounds. Wef: 22/8/2003 Vide PT 2366 Att: SS & Co. Sweden Rec: 6827/8 dt 25/08/2004 02/03/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 19/08/2004 Warrant signed on 2367 Chemical Compounds. Wef: 22/08/2003 Vide PT 2367 Att: SS & Co. Sweden Rec: 6830/1 dt 25/08/2004 02/03/2005

[1,8] Naphthyridin-2-Ones and Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 19/08/2004 Warrant signed on 2368 related compounds for the LLC Plains, New Jersey 07950, Wef: 22/08/2003 Vide PT 2368 Rec: 6833/4 dt 25/08/2004 15/03/2005 treatment of schizophrenia. Att: SS & Co. United States of America Compounds for the treatment Eastern Point Road, Pfizer Products Inc. Filing Date: 19/08/2004 Warrant signed on 2370 of neurodegenerative Groton, Connecticut Wef: 21/08/2003 Vide PT 2370 Att: SS & Co. Rec: 6721/2 dt 23/08/2004 02/03/2005 disorders. 06340, USA

PO Box 4000, Route 206 N- Alkylated diaminopropane Bristol-Myers Squibb and Province Line Road, Filing Date: 20/08/2004 Warrant signed on 2371 derivatives as modulators of Company Wef: 21/08/2003 Vide PT 2371 Princeton, New Jersey, Rec: 6717/8 dt 23/08/2004 29/03/2005 chemokine receptor activity Att: MAMO TCV Advocates USA

PO Box 4000, Route 206 Substituted cycloalkyamine Bristol-Myers Squibb and Province Line Road, Filing Date: 20/08/2004 Warrant signed on 2372 derivatives as modulators of Company Wef: 21/08/2003 Vide PT 2372 Princeton, New Jersey, Rec: 6714/5 dt 23/08/2004 29/03/2005 chemokine receptor activity Att: MAMO TCV Advocates USA

Sanofi-Aventis 174 Avenue de France, F- Filing Date: 24/08/2004 Warrant signed on 2373 New Compounds. Wef: 29/08/2003 Vide PT 2373 Att: SS & Co. 75013 Paris, France Rec: 6842/3 dt 25/08/2004 02/03/2005

Substituted quindinone One Amgen Center Drive, Filing Date: 25/08/2004 Amgen Inc. Wef: 25/08/2003 Wef: Warrant signed on 2374 derivatives and Methods of Thousand Oaks, California Rec: 6852/3 dt Vide PT 2374 Att: B&M Patentbureau 24/08/2004 02/03/2005 use. 91320-1799, USA 25/08/2004

Substituted 2,3 Dihydro - IH - One Amgen Center Drive, Amgen Inc. Filing Date: 25/08/2004 Wef: 25/08/2003 Warrant signed on 2375 Isoindol- 1- One derivatives Thousand Oaks, California Vide PT 2375 Att: B&M Patentbureau Rec: 6856/7 dt 25/08/2004 Wef: 24/08/2004 11/04/2005 and Methods of use. 91320-1799, USA

Substituted heterocyclic One Amgen Center Drive, Amgen Inc Filing Date: 27/08/2004 Wef: 27/08/2003 Warrant signed on 2376 compounds and Methods of Thousand Oaks, California Vide PT 2376 Att: Dr. Maria Chetcuti Cauchi Rec: 6946/7 dt 27/08/2004 Wef: 20/08/2004 15/03/2005 use 91320-1799, USA

235 East 42nd Street, New Aryl or heteroarly amide Pfizer Inc. Filing Date: 31/08/2004 Warrant signed on 2377 York, New York 10017, Wef: 03/09/2003 Vide PT 2377 compounds. Att: SS & Co. Rec: 6995/6 dt 31/08/2004 15/03/2005 USA

235 East 42nd Street, New Process for the preparation of Pfizer Inc. Filing Date: 31/08/2004 Wef: 04/09/2003 Wef: Warrant signed on 2378 York, New York 10017, Vide PT 2378 substituted aryl pyrazoles Att: SS & Co. Rec: 6992/3 dt 31/08/2004 02/07/2004 15/03/2005 USA

Filing Date: 31/08/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2379 Therapeutic treatment Rec: 6989/90 dt Wef: 05/09/2003 Vide PT 2379 Att: SS & Co. Sweden 15/03/2005 31/08/2004

Benzimidazolone compounds 235 East 42nd Street, New Pfizer Inc. Filing Date: 31/08/2004 Warrant signed on 2380 having 5- HT4 receptor York, New York 10017, Wef: 03/09/2003 Vide PT 2380 Att: SS & Co. Rec: 6986/7 dt 31/08/2004 15/03/2005 agonistic activity. USA Glaxo Wellcome House, Berkeley Avenue, Filing Date: 31/08/2004 Warrant signed on 2381 Pharmaceutical formulation Glaxo Group Limited Wef: 02/09/2003 Vide PT 2381 Greenford, Middlesex MB6 Rec: 6983/4 dt 31/08/2004 15/03/2005 ONN, Great Britain

Wef: 09/09/2003 Combination of Serotonin Eastern Point Road, Filing Date: 31/08/2004 Wef: 23/09/2004 reuptake inhibitors and Pfizer Products Inc. Groton, Connecticut Warrant signed on 2382 Rec: 6980/1 dt Wef: 30/09/2004 Vide PT 2382 norephinephrine reuptake Att: SS & Co. 06340, United States of 15/03/2005 31/08/2004 Wef: 30/09/2004 inhibitors America Wef: 03/06/2004

15 Stanhope Gate, Astrazeneca UK Limited Filing Date: 02/09/2004 Wef: 10/09/2003 Warrant signed on 2383 Chemical compounds London WIK ILN, United Vide PT 2383 Att: SS & Co. Rec: 7067/8 dt 03/09/2004 Wef: 04/03/2004 15/03/2005 Kingdom

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 02/09/2004 Wef: 13/09/2003 Wef: Warrant signed on 2384 Chemical Compounds Vide PT 2384 Att: SS & CO. Sweden Rec: 7070/1 dt 03/09/2004 12/05/2004 15/03/2005

George Kieffer Sattlewaren Kunihohstrasse 7, D- Filing Date: 03/09/2004 Warrant signed on 2385 Adjustable Saddle Tree fabrik GMBH Wef: N/A Vide PT 2385 81929 Mundev, Germany Rec: 7077/8 dt 03/09/2004 16/03/2006 Att: E. Mallia & Associates

4th Floor, Cavendish Filing Date: 06/09/2004 Arrow No7 Limited Wef: 15/09/2003 Wef: Warrant signed on 2388 Buccal Drug Delivery Square, London WIG Rec: 7129/30 dt Vide PT 2388 Att: SS & Co 16/02/2004 11/04/2005 OPE, United Kingdom 06/09/2004

210 Tabor Road, Morris Plains, New Jersey NJ Warner Lambert Company 07950, United States of Filing Date: 09/09/2004 Warrant signed on 2389 Antibodies to M-CSF L.L.C & Abgenix Inc. America & 6701 Kaiser Wef: 10/09/2003 Vide PT 2389 Rec: 7193/4 dt 10/09/2004 15/03/2005 Att: S.S. & Co Drive Fremont, California 94555, United States of America

Therapeutic Human Anti-MHC Fraunhoferstr 20, 82 152 Filing Date: 09/09/2004 GPC Biotech AG Warrant signed on 2390 Class II Antibodies and their Martinsried, Munich, Rec: P585219 dt Wef: 09/09/2003 Vide PT 2390 Att: DR M. Chetcuti Cauchi 15/03/2005 uses Germany 09/09/2004

PO Box 4000, Route 206 Bristol-Myers Squibb Filing Date: 10/09/2004 Cycloalkyl heterocycles for and Province Line Road, Warrant signed on 2391 Company Rec: 7189/90 dt Wef: 11/09/2003 Vide PT 2391 treating hepatitis C virus Princeton, New Jersey, 15/03/2005 Att: MAMO TCV Advocates 10/09/2004 USA

Rapid dissolution formulation One Amgen Center Drive, Amgen Inc. Filing Date: 13/09/2004 Warrant signed on 2392 of a calcium receptor-active Thousand Oaks, California Wef: 12/09/2003 Vide PT 2392 Att: B&M Patentbureau Rec: 7245/6 dt 13/09/2004 15/03/2005 compound. 91320-1799, USA Filing Date: 14/09/2004 Astrazeneca AB SE - 151 85 Sodertalje , Wef: 16/09/2003 Warrant signed on 2393 Quinazoline derivatives. Rec: 7277/8 dt Vide PT 2393 Att: SS & Co. Sweden Wef: 25/09/2003 11/04/2005 14/09/2004

HIV protease inhibitors, compositions containing the 235 East 42nd Street, New Filing Date: 14/09/2004 Pfizer Inc. Wef: 17/09/2003 Warrant signed on 2394 same, their pharmaceutical York, New York 10017, Rec: 7280/1 dt Vide PT 2394 Att: SS & Co. Wef: 04/12/2003 11/04/2005 uses and materials for their USA 14/09/2004 synthesis.

Filing Date: 14/09/2004 Astrazeneca AB SE - 151 85 Sodertalje , Warrant signed on 2395 New Combination. Rec: 7283/4 dt Wef: 18/09/2003 Vide PT 2395 Att: SS & Co. Sweden 11/04/2005 14/09/2004

Astrazeneca AB SE - 151 85 Sodertalje , Filing Date: 14/09/2004 Warrant signed on 2396 Novel Compounds. Wef: 18/09/2003 Vide PT 2396 Att: SS & Co. Sweden Rec: 7286/7 dt 14/09/2004 11/04/2005

Astrazeneca AB SE - 151 85 Sodertalje , Filing Date: 14/09/2004 Warrant signed on 2397 Novel Compounds. Wef: 18/09/2003 Vide PT 2397 Att: SS & Co. Sweden Rec: 7288/9 dt 14/09/2004 11/04/2005

Astrazeneca AB SE - 151 85 Sodertalje , Filing Date: 14/09/2004 Warrant signed on 2398 Quinazoline derivatives. Wef: 14/09/2003 Vide PT 2398 Att: SS & Co. Sweden Rec: 7290/1 dt 14/09/2004 11/04/2005

Astrazeneca AB SE - 151 85 Sodertalje , Filing Date: 14/09/2004 Wef: 16/09/2003 Warrant signed on 2399 Quinazoline derivatives. Vide PT 2399 Att: SS & Co. Sweden Rec: 7294/5 dt 14/09/2004 Wef: 19/03/2004 11/04/2005

Astrazeneca AB SE - 151 85 Sodertalje , Filing Date: 14/09/2004 Wef: 16/09/2003 Warrant signed on 2400 Quinazoline derivatives. Vide PT 2400 Att: SS & Co. Sweden Rec: 7297/8 dt 14/09/2004 Wef: 19/03/2004 11/04/2005

289 Bellaesis Road, Cipla Limited Filing Date: 14/09/2004 Warrant signed on 2401 Multi-dose inhaler Mumbai Central, Mumbai Wef: N/A Vide PT 2401 Att: SS & Co. Rec: 7274/5 dt 14/09/2004 15/03/2005 00 008, India

Warner-Lambert Company 201 Tabor Road, Morris Amino acids with affinity for Filing Date: 15/09/2004 Wef: 25/09/2003 Warrant signed on 2402 LLC Plains, New Jersey 07950, Vide PT 2402 α2δ- protein Rec: 7324/5 dt 15/09/2004 Wef: 30/09/2003 11/04/2005 Att: SS & Co. USA

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/09/2004 Warrant signed on 2403 New Compounds. Wef: 24/09/2003 Vide PT 2403 Att: SS & Co. Sweden Rec: 7327/8 dt 15/09/2004 11/04/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/09/2004 Wef: 19/09/2003 Warrant signed on 2404 Quinazoline derivatives. Vide PT 2404 Att: SS & Co. Sweden Rec: 7330/1 dt 15/09/2004 Wef: 14/05/2004 11/04/2005 PO Box 4000, Route 206 Solid dosage formulation Bristol-Myers Squibb and Province Line Road, Filing Date: 15/09/2004 Warrant signed on 2405 containing a factor Xa Company Wef: 16/09/2003 Vide PT 2405 Princeton, New Jersey, Rec: 7371/2 dt 22/09/2004 11/04/2005 inhibitor & Method. Att: MAMO TCV Advocates United States of America

Substituted triazole 235 East 42nd Street, New Wef: 22/09/2003 Pfizer Inc. Filing Date: 16/09/2004 Warrant signed on 2406 derivatives as oxytocin York, New York Wef: 12/02/2004 Wef: Vide PT 2406 Att: SS & Co. Rec: 7391/2 dt 22/09/2004 11/04/2005 antagonists. 10017, USA 05/07/2004

Benzimidazole derivatives, compositions containing Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 16/09/2004 Warrant signed on 2407 Wef: 26/09/2004 Vide PT 2407 them, preparation thereof and Att: SS & Co. Sweden Rec: 7388/9 dt 22/09/2004 11/04/2005 uses thereof.

Benzimidazole derivatives, compositions containing Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 16/9/2004 Warrant signed on 2408 Wef: 26/09/2003 Vide PT 2408 them, preparation thereof and Att: SS & Co. Sweden Rec: 7385/6 dt 22/09/2004 11/04/2005 uses thereof.

Benzimidazole derivatives, compositions containing Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 16/09/2004 Warrant signed on 2409 Wef: 26/09/2003 Vide PT 2409 them, preparation thereof and Att: SS & Co. Sweden Rec: 7382/3 dt 22/09/2004 11/04/2005 uses thereof.

Benzimidazole derivatives, Filing Date: 16/09/2004 compositions containing Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2410 Rec: 7379/80 dt Wef: 26/09/2003 Vide PT 2410 them, preparation thereof and Att: SS & Co. Sweden 11/04/2005 22/09/2004 uses thereof.

Novel 1,2,3,6,7,8 - Substituted indolizin derivatives, inhibitors Sanofi-Aventis 174 Avenue de France, Filing Date: 16/09/2004 Warrant signed on 2411 of FGF'S, Method for Wef: 18/09/2003 Vide PT 2411 Att: SS & Co. FR-75013 Paris, France Rec: 7376/7 dt 22/09/2004 11/04/2005 preparing them and pharmaceutical.

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 22/09/2004 Warrant signed on 2412 Calcilyttic compounds. Wef: 24/09/2003 Vide PT 2412 Att: SS & Co Greenford, Middlesex UB6 Rec: 7397/8 dt 22/09/2004 11/04/2005 ONN, Great Britain.

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 22/09/2004 Warrant signed on 2413 Compounds. Wef: 27/09/2004 Vide PT 2413 Att: SS & Co Greenford, Middlesex UB6 Rec: 7400/1 dt 22/09/2004 11/04/2005 ONN, Great Britain. Pyrrolopyridazine compounds PO Box 4000, Route 206 Bristol-Myers Squibb and methods of use thereof and Province Line Road, Filing Date: 23/09/2004 Warrant signed on 2414 Company Wef: 26/09/2003 Vide PT 2414 for the treatment of Princeton, New Jersey , Rec: 7531/2 dt 27/09/2004 11/04/2005 Att: MAMO TCV Advocates proliferative disorders. United States of America

Janssen Pharmaceutica HIV replication inhibiting Turnhoutseweg 30, B- Filing Date: 24/09/2004 Warrant signed on 2415 N.V. Wef: 25/09/2003 Vide PT 2415 purine derivatives. 2340 Beerse, Belgium Rec: 7461/2 dt 24/09/2004 11/04/2005 Att: EMD Advocates

PO Box 4000, Route 206 Bristol-Myers Squibb HMG-CoA reductase inhibitors and Province Line Road, Filing Date: 24/09/2004 Warrant signed on 2416 Company Wef: 25/09/2003 Vide PT 2416 and method. Princeton, New Jersey , Rec: 7492/3 dt 24/09/2004 11/04/2005 Att: MAMO TCV Advocates United States of America

Wef: 03/10/2003 Wef: Pfizer Inc. 235 East 42nd Street , Filing Date: 28/09/2004 Warrant signed on 2417 Tropane derivatives. 27/10/2003 Wef: Vide PT 2417 Att: SS & Co New York 10017, USA Rec: 7563/4 dt 28/09/2004 19/04/2005 19/08/2004

One Amgen Center Drive, Vanilloid receptor ligands and Amgen Inc. Filing Date: 29/09/2004 Warrant signed on 2418 Thousand Oaks, CA Wef: 30/09/2003 Vide PT 2418 their use in treatments. Att: Dr. Maria Chetcuti Cauchi Rec: 7586/7 dt 29/09/2004 11/04/2005 91320-1799, USA.

PO Box 4000, Route 206 Bristol-Myers Squibb Modulators of serotonin and Province Line Road, Filing Date: 05/10/2004 Wef: 04/10/2003 Warrant signed on 2419 Company Vide PT 2419 receptors. Princeton, New Jersey , Rec: 7758/9 dt 11/10/2004 Wef: 04/02/2004 19/04/2005 Att: MAMO TCV Advocates United States of America

PO Box 4000, Route 206 Methods for treating IGFIR- Bristol-Myers Squibb and Province Line Road, Filing Date: 05/10/2004 Warrant signed on 2420 Inhibitor induced Company Wef: 06/10/2003 Vide PT 2420 Princeton, New Jersey , Rec: 7754/6 dt 11/10/2004 19/04/2005 hyperdycemia Att: MAMO TCV Advocates United States of America

One Franklin Plaza, P.O. Smithkline Beecham Box 7929, Philadelphia, Filing Date: 07/10/2004 Warrant signed on 2422 Chemical compounds. Corporation Wef: 09/10/2003 Vide PT 2422 PA 19101, United States Rec: 7766/7 dt 11/10/2004 19/04/2005 Att: SS & Co. of America

Thiophene -2-Carboxamide derivatives, their preparation Sanofi-Aventis 174 Avenue de France, Filing Date: 08/10/2004 Warrant signed on 2425 Wef: 10/10/2003 Vide PT 2425 and their therapeutical Att: SS & Co. FR-75013 Paris, France Rec: 7743/4 dt 11/10/2004 19/04/2005 application. PO Box 4000, Route 206 Pyrazole derivatives as Bristol-Myers Squibb and Province Line Road, Filing Date: 11/10/2004 Warrant signed on 2427 cannabinoid receptor Company Wef: 10/10/2003 Vide PT 2427 Princeton, New Jersey , Rec: 7814/5 dt 11/10/2004 19/04/2005 modulators. Att: MAMO TCV Advocates United States of America

PO Box 4000, Route 206 Bristol-Myers Squibb Fully human antibodies and Province Line Road, Filing Date: 11/10/2004 Warrant signed on 2428 Company Wef: 10/10/2003 Vide PT 2428 against human 4-1BB Princeton, New Jersey , Rec: 7817/8 dt 11/10/2004 19/04/2005 Att: MAMO TCV Advocates United States of America

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 12/10/2004 Warrant signed on 2429 Chemical Compounds Wef: 16/10/2003 Vide PT 2429 Att: SS & Co. Sweden Rec: 7845/6 dt 12/10/2004 06/05/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 12/10/2004 Warrant signed on 2430 Protein Wef: 14/10/2003 Vide PT 2430 Att: SS & Co. Sweden Rec: 7848/9 dt 12/10/2004 19/04/2005

Astrazeneca AB SE - 151 85 Sodertalje Filing Date: 12/10/2004 Wef: 17/10/2003 Wef: Warrant signed on 2431 Novel Compounds Vide PT 2431 Att: SS & CO. Sweden. Rec: 7851/2 dt 12/10/2004 02/06/2004 06/05/2005

Glaxo Wellcome House, Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Filing Date: 12/10/2004 Warrant signed on 2432 Rec: 14/10/2003 Vide PT 2432 receptor antagonists. Att: SS & Co Greenford, Middlesex UB6 Rec: 7854/5 dt 12/10/2004 19/04/2005 ONN, Great Britain

Pharmaceutical formulations. Methods and dosing 3621 South State Street , Filing Date: 12/10/2004 Wef: 20/10/2003 Wef: Esperion Therapeutics Inc. Warrant signed on 2433 regiments for the treatment 695 KMS Place, Ann Rec: 7863/4 dt 03/11/2003 Wef: Vide PT 2433 Att: B&M Patentbureau 06/05/2005 and prevention of acute Arbor, MI 48108, NS 12/10/2004 14/05/2004 coronary syndromes

Tablet with aqueous-based Novartis AG Lichstrasse 35, CH-4056 Filing Date: 15/10/2004 Warrant signed on 2434 Wef: 16/10/2003 Vide PT 2434 sustained release coating. Att: MAMO TCV Advocates Basel, Switzerland Rec: 7928/9 dt 15/10/2004 06/05/2005

Sulfoximine-Substituted pyrimidines as CDK and/or Schering Filing Date: 15/10/2004 Warrant signed on 2435 VEGF inhibitors, their Aktiengesellschaft Berlin 13342, Germany Wef: 16/10/2003 Vide PT 2435 Rec: 7932/3 dt 15/10/2004 06/05/2005 production and use as Att: MAMO TCV Advocates pharmaceutical agents.

Thiazolidnone, their Schering Filing Date: 15/10/2004 Warrant signed on 2436 production and use as Aktiengesellschaft Berlin 13342, Germany Wef: 31/10/2003 Vide PT 2436 Rec: 7936/7 dt 15/10/2004 06/05/2005 pharmaceutical agents Att: MAMO TCV Advocates Novel processes for preparing Galderma Research & 635 route des Lucioles, Filing Date: 15/10/2004 4-[4-(4-methoxymethoxy-4- Warrant signed on 2437 Development, S.N.C., 06902 Sophia Antipolis Rec: 7949/50 dt Wef: 17/10/2003 Vide PT 2437 methylbiphenyl- 2-YL) but-3- 06/05/2005 Att: SS & CO. Cedex, France 15/10/2004 EN-(E)-1-YNYL] Benzoic Acid

Novel RABbeta receptor- activating ligand, process for Galderma Research & 635 route des Lucioles, Filing Date: 15/10/2004 Warrant signed on 2438 preparing it and use thereof in Development, S.N.C., 06902 Sophia Antipolis Wef: 23/10/2003 Vide PT 2438 Rec: 7951/2 dt 15/10/2004 06/05/2005 human medicine and in Att: SS & CO. Cedex, France cosmetics.

Novel ligands that activate the Galderma Research & 635 route des Lucioles, rar receptors, and use thereof Filing Date: 15/10/2004 Warrant signed on 2439 Development, S.N.C., 06902 Sophia Antipolis Wef: 17/10/2003 Vide PT 2439 in human medicine and in Rec: 7954/5 dt 15/10/2004 06/05/2005 Att: SS & CO. Cedex, France cosmetics.

Cyclopropylmethanone Sanofi-Aventis 174 Avenue de France, Filing Date: 15/10/2004 Wef: 17/10/2003 Warrant signed on 2440 derivatives, their preparation Vide PT 2440 Att: SS & Co. FR-75013 Paris, France Rec: 7957/8 dt 15/10/2004 Wef: 11/08/2004 06/05/2005 and their use in therapy.

Glaxo Wellcome House, Filing Date: 15/10/2004 Muscarinic Acetylcholine Glaxo Group Limited Berkeley Avenue, Warrant signed on 2441 Rec: 7959/60 dt Wef: 17/10/2003 Vide PT 2441 receptor antagonists. Att: SS & Co Greenford, Middlesex UB6 06/05/2005 15/10/2004 ONN, Great Britain.

Process for the purification of Zambon Group SPA Via della Chimica, 9, Filing Date: 15/10/2004 Warrant signed on 2442 Wef: N/A Vide PT 2442 gabapentin. Att: S S & Co. 36100 Vicenza, Italy Rec: 7962/3 dt 15/10/2004 19/04/2006

One 58, South Service Imidazopyrazine tyrosine OSI Pharmaceuticals Filing Date: 15/10/2004 Warrant signed on 2443 Road, Suite 110, Melville, Wef: 15/10/03 Vide PT 2443 Kinase Inhibitors. Att: SS & Co. Rec: 7946/7 dt 15/10/2004 19/04/2005 NY1747, USA

2-(3,4-Dimethylphenyl)-4-{[2- hydroxy-3-(1H-Tetrazol-5-YL) Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 20/10/2004 Warrant signed on 2445 Biphenyl-3-YL] hydrozono}-5- Corporation Box 7929, Pennsylvania, Rec: 8024/5 dt Wef: 22/10/2003 Vide PT 2445 06/05/2005 methyl-2,4-dihydropyrazol-3- Att:SS & Co. USA. 20/10/2004 one choline.

Susbtituted heterocyclic One Amgen Center Drive, Amgen Inc. Filing Date: 21/10/2004 Wef: 21/10/2003 Wef: Warrant signed on 2446 compounds and Methods of Thousand Oaks, CA Vide PT 2446 Att: Dr. Maria Chetcuti Cauchi Rec: 8041/2 dt 21/10/2004 20/10/2004 01/09/2005 use. 91320-1799, USA

Process for purifying proteins One Amgen Center Drive, in a hydrophobic interaction Amgen Inc. Filing Date: 22/10/2004 Warrant signed on 2447 Thousand Oaks, CA Wef: 24/10/2003 Vide PT 2447 chromatography flow-through Att: MAMO TCV Advocates Rec: 8056/7 dt 22/10/2004 06/05/2005 91320-1799, USA fraction. Controlled release sterile Otsuka Pharmaceutical Co. 3-2-27, Otedori, Chuo-ku, Filing Date: 22/10/2004 Warrant signed on 2448 injectable aripiprazole Ltd. Wef: 23/10/2003 Vide PT 2448 Osaka 541-0045, Japan Rec: 8060/1 dt 22/10/2004 06/05/2005 formulation and method. Attn: MAMO TCV Advocates

Filing Date: 22/10/2004 Astrazeneca AB SE - 151 85, Sodertalje, Warrant signed on 2449 Novel Compounds Rec: 8111/2 dt Wef: 23/10/2003 Vide PT 2449 Att: SS & Co. Sweden 06/05/2005 22/10/2004

15 Stanhope Gate, Astrazeneca UK Limited London, WIK ILN, United Chemical Process & and Shionogi & Company Kingdom & 1-8 Filing Date: 22/10/2004 Warrant signed on 2450 Wef: 24/10/2003 Vide PT 2450 Intermediates Limited Doshomachi 3-chome, Rec: 8108/9 dt 22/10/2004 06/05/2005 Att: SS & Co Chuo-Ku, Osaka 541- 0040, Japan MT PT Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract No

Use of a pyrazole derivative for preparing medicinal products that are useful in the Filing Date: 22/10/2004 prevention and treatment of Sanofi-Aventis 174 Avenue de France, Warrant signed on 2451 Rec: 8094/5 dt Wef: 24/10/2003 Vide PT 2451 dyslipidaemias and of Att: SS & Co. FR-75013 Paris, France 06/05/2005 22/10/2004 diseases related to dyslipidaemias and/or to obesity

Filing Date: 22/10/2004 Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 2452 Amide derivatives Rec: 8091/2 dt Wef: 24/10/2003 Vide PT 2452 Att: SS & Co. Sweden 06/05/2005 22/10/2004

289 Bellasio Road, Filing Date: 22/10/2004 Transdermal pharmaceutical Cipla Limited, Mumbai Central, Mumbai Warrant signed on 2453 Rec: 8081/2 dt Wef: 23/10/2003 Vide PT 2453 formulations. Att: SS & Co. 400008, Maharashta, 06/05/2005 22/10/2004 India

One Amgen Center Filing Date: 22/10/2004 Wef: 22/10/2003 Antagonists for the bradyknin Amgen Inc. Warrant signed on 2454 Drive, Thousand Oaks, Rec: 8099/8100 dt Wef: 24/01/2004 Vide PT 2454 B1 receptor Att: Dr. Maria Chetcuti-Cauchi 01/09/2005 CA 91320-1799, USA. 22/10/2004 Wef: 21/10/2004

The use of 1- Eckenheimer aminocyclohexane derivatives Filing Date: 22/10/2004 Merz Pharma GmbH & Co. KGAA Landstrasse 100, D - Warrant signed on 2455 to modify deposition of Rec: 8102/3 dt Wef: 22/10/2003 Vide PT 2455 Att: Dr. Maria Chetcuti-Cauchi 60318, Frankfurt Main, 06/05/2005 fibrillogenic as peptides in 22/10/2004 Germany amyloidopathies.

SE - 151 85 Filing Date: 26/10/2004 Astrazeneca AB Warrant signed on 2456 Chemical compounds Sodertalje Rec: 8165/7 dt Wef: 29/10/2004 Vide PT 2456 Att: SS & Co. 06/05/2005 Sweden. 26/10/2004

Compositions and Methods to One Amgen Center Filing Date: 27/10/2004 modulate an immune Amgen Inc. Warrant signed on 2457 Drive, Thousand Oaks, Rec: 8176/7 dt Wef: 27/10/2003 Vide PT 2457 response to an immunogenic Att: Dr. Maria Chetcuti-Cauchi 06/05/2005 CA 91320-1799, USA. 27/10/2004 therapeutic agent

Methods for preparing 7-(2¹- Substituted-B-D-ribofuranosyl)- 505 Penobscot Drive, Filing Date: 27/10/2004 Genelabs Technologies Inc Att: Warrant signed on 2458 4-(NR²R³)-5-(Substituted ethyn- Redwood City, CA Rec: 8182/4 dt Wef: 27/10/2003 Vide PT 2458 SS & Co. 06/05/2005 1-YL)-Pyrrolo[2,3-D)Pyrimidine 94063, U.S.A 27/10/2004 derivatives. 505 Penobscot Drive, Filing Date: 27/10/2004 Nucleoside compounds for Genelabs Technologies Inc Att: Warrant signed on 2459 Redwood City, CA Rec: 8186/7 dt Wef: 27/10/2003 Vide PT 2459 treating viral infections. SS & Co. 06/05/2005 94063, U.S.A 27/10/2004

505 Penobscot Drive, Filing Date: 27/10/2004 Nucleoside compounds for Genelabs Technologies Inc Att: Warrant signed on 2460 Redwood City, CA Rec: 8189/90 dt Wef: 27/10/2003 Vide PT 2460 treating viral infections. SS & Co. 06/05/2005 94063, U.S.A 27/10/2004

6166 Nancy Ridge Drive, Tetrazole derivatives and Arena Pharmaceuticals, Inc & San Diego, California Filing Date: 29/10/2004 Methods of treatment of Warrant signed on 2461 Merck & Co. Inc. 92121,USA & 126 East Rec: 8228/9 dt Wef: 31/10/2003 Vide PT 2461 metabolic-related disorders 17/05/2005 Att: Dr. Maria Chetcuti Cauchi Lincoln Avenue, Railway, 29/10/2004 thereof. New Jersey 07065 USA.

Filing Date: 29/10/2004 Pharmaceutical licofelone Merckle GmbH Graf-Arx-Sti, 3 Ulm Warrant signed on 2462 Rec: 8239/40 dt Rec: 31/10/2003 Vide PT 2462 formulation. Att: MAMO TCV Advocates 89079, Germany 06/05/2005 29/10/2004

Hertford Road, Filing Date: 02/11/2004 Novel 5-HT2A receptor Merck Sharp & Dohme Limited Hoddesdon, Warrant signed on 2463 Rec: 8319/20 dt Rec: 10/11/2003 Vide PT 2463 ligands. Att: Dr. Maria Chetcuti Cauchi Hertfordshire EN 11 9BU, 09/06/2005 02/11/2004 England

Hertford Road, Substituted nitrogen- Hoddesdon, containing six-Membered Merck Sharp & Dohme Limited & Filing Date: 02/11/2004 Wef: 10/11/2003 Hertfordshire EN 11 9BU, Warrant signed on 2464 amino-heterocycles as Merck & Co. Inc. Att: Rec: 8322/3 dt Wef: 05/04/2004 Vide PT 2464 England & 126 East 17/05/2005 vanilloid-1 receptor Dr. Maria Chetcuti Cauchi 02/11/2004 Wef: 08/10/2004 Lincoln Avenue, Railway, antagonists for treating pain. New Jersey 07065, USA

Eastern Point Road, Bicyclic pyrazolyl and Filing Date: 02/11/2004 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2465 imodazolyl compounds and Rec: 8343/4 dt Wef: 07/11/2003 Vide PT 2465 Att: SS & Co. 06340, United States of 17/05/2005 uses thereof. 02/11/2004 America

Filing Date: 02/11/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2466 Chemical compounds. Rec: 8340/1 dt Wef: 07/11/2003 Vide PT 2466 Att: SS & Co. Sweden 17/05/2005 02/11/2004

Glaxo Wellcome House, Filing Date: 02/11/2004 Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Warrant signed on 2467 Rec: 8337/8 dt Wef: 04/11/2003 Vide PT 2467 receptor antagonists. Att: SS & Co Greenford Middlesex 17/05/2005 02/11/2004 UB6 ONN, Great Britain

Filing Date: 02/11/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2468 Chemical compounds. Rec: 8334/5 dt Wef: 05/11/2003 Vide PT 2468 Att: SS & Co. Sweden 17/05/2005 02/11/2004 Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 02/11/2004 Warrant signed on 2469 Chemical compounds. Wef: 07/11/2003 Vide PT 2469 Att: SS & Co. Sweden Rec: 8331/2 dt 02/11/04 17/05/2005

One Amgen Center Filing Date: 04/11/2004 Monkey Immunoglobulin Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2471 Rec: 8423/4 dt Wef: 07/11/2003 Vide PT 2471 sequences. Att: MAMO TCV Advocates CA 91320-1799, United 17/05/2005 08/11/2004 States of America

One Amgen Center Filing Date: 04/11/2004 Antibodies that bind Immunex Corporation Drive, Thousand Oaks, Warrant signed on 2472 Rec: 8420/1 dt Wef: 07/11/2003 Vide PT 2472 interleukin - 4 receptor Att: MAMO TCV Advocates CA 91320-1799, United 17/05/2005 08/11/2004 States of America

Toldbodgade 33, DK- Methods for treating disorders Genmab A/S Filing Date: 05/11/2004 Warrant signed on 2474 1253 Copenhagen K, Wef: 06/11/2003 Vide PT 2474 involving monocytes Att: Dr. Maria Chetcuti Cauchi Rec. P585328 dt 5/11/04 17/05/2005 Denmark

Eckenheimer Compositions comprising Filing Date: 05/11/2004 Merz Pharma GmbH & Co. KGAA Landstrasse 100, D- Warrant signed on 2475 cyclohexylamines and Rec: P585329 dt Wef: 05/11/2003 Vide PT 2475 Att: Dr. Maria Chetcuti Cauchi 60318 Frankfurt Main, 17/05/2005 aminoadamantanes 05/11/2004 Germany

Pharmaceutical compositions Filing Date: 09/11/2004 for oral administration of a Sanofi-Aventis 174 Avenue de France, Warrant signed on 2476 Rec: 8483/4 dt Wef: 10/11/2003 Vide PT 2476 pyrazole-3-carboxamide Att: SS & Co. FR-75013 Paris, France 17/05/2005 09/11/2004 derivative.

Glaxo Wellcome House, Filing Date: 09/11/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2477 Chemical Compounds. Rec: 8480/1 dt Wef: 12/11/2003 Vide PT 2477 Att: SS & Co. Greenford Middlesex 17/05/2005 09/11/2004 UB6 ONN, Great Britain

Filing Date: 09/11/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2478 Quinazoline derivatives. Rec: 8477/8 dt Wef: 13/11/2003 Vide PT 2478 Att: SS & Co. Sweden 17/05/2005 09/11/2004

Novel compound, SmithKline Beecham (Cork) Curraghbinny, Filing Date: 09/11/2004 corresponding compositions, Warrant signed on 2479 Limited Carrygaline, County Rec: 8474/5 dt Wef: 12/11/2003 Vide PT 2479 preparation and/or treatment 17/05/2005 Att: SS & Co. Cork, Eire, Ireland 09/11/2004 methods.

Filing Date: 09/11/2004 Process for the preparation of Zambon Group SpA Via della Chimica 9, Warrant signed on 2480 Rec: 8471/2 dt Wef: 11/11/2003 Vide PT 2480 Gabapentin Att: SS & Co. 36100 Vicenza, Italy 17/05/2005 09/11/2004 One Procter and Gamble Filing Date: 10/11/2004 Bicyclic pyrazolone cytokine The Procter & Gamble Company Warrant signed on 2481 Plaza, Cincinnati, Ohio Rec: 8522/3 dt Wef: 10/11/2003 Vide PT 2481 inhibitors. Att: SS & Co. 17/05/2005 45202, USA 11/11/2004

PO Box 4000, Route 206 Monocyclic N-aryl hydantoin Filing Date: 11/04/2004 Bristol-Myers Squibb Company & Province Line Road, Warrant signed on 2482 Modulators of androgen Rec: 8561/2 dt Wef: 13/11/2003 Vide PT 2482 Att: MAMO TCV Advocates Princeton, New Jersey, 24/05/2005 receptor function. 11/11/2004 USA

Eastern Point Road, Filing Date: 12/11/2004 Hydrazide derivatives and Pfizer Products Inc Warrant signed on 2483 Groton, Connecticut Rec: 8577/8 dt Wef: 13/11/2003 Vide PT 2483 their uses thereof Att: SS & Co. 17/05/2005 06340, USA 12/11/2004

Filing Date: 12/11/2004 Pyrazole derivatives and uses Astrazeneca AB SE - 151 85 Sodertalje, Wef: 17/11/2003 Warrant signed on 2484 Rec: 8574/5 dt Vide PT 2484 thereof Att: SS & Co. Sweden Wef: 25/03/2004 02/06/2005 12/11/2004

235 East 42nd Street, Filing Date: 16/11/2004 Pfizer Inc. Warrant signed on 2486 Novel pharmaceuticals. New York, New York Rec: 8638/9 dt Wef: 24/11/2003 Vide PT 2486 Att: SS & Co 02/06/2005 10017, USA 16/11/2004

Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 16/11/2004 Wef: 17/11/2003 Warrant signed on 2487 Chemical Compounds. Corporation Box 7929, Philadelphia, Rec: 8641/2 dt Vide PT 2487 Wef: 19/12/2003 02/06/2005 Att:SS & Co. PA 19101, USA 16/11/2004

201 Tabor Road, Morris Filing Date: 16/11/2004 Quinolone Antibacterial Warner-Lambert Company LLC Wef: 18/11/2003 Warrant signed on 2488 Plains, New Jersey Rec: 8644/5 dt Vide PT 2488 agents Att: SS & CO Wef: 31/08/2004 02/06/2005 07950, USA 16/11/2004

6-Alkenyl and 6-Phenylalkyl substituted 2-Quinolinones Filing Date: 18/11/2004 Janssen Pharmaceutica N.V., Turnhoutseweg 30, B- Wef: 20/11/2003 Warrant signed on 2489 and 2-Quinoxalinones as poly Rec: P585332 dt Vide PT 2489 Att: Ellul Mifsud & Debono. 2340 Beerse, Belgium Wef: 05/12/2003 02/07/2005 (ADP-Ribose) Polymerase 18/11/2004 Inhibitors.

Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 19/11/2004 Warrant signed on 2490 Novel use. Corporation Box 7929, Philadelphia, Rec: 8717/8 dt Wef: 21/11/2003 Vide PT 2490 02/06/2005 Att:SS & Co. PA 19101, USA 19/11/2004

Composition in the form of a spray comprising a Galderma Research & 635 route des Lucioles, Filing Date: 19/11/2004 Warrant signed on 2491 pharmaceutical active agent at Development, S.N.C. BP57, 06902 Sophia Rec: 8714/5 dt Wef: 21/11/2003 Vide PT 2491 02/06/2005 least one volatile silicone and Att: SS & CO. Antipolis Cedex, France 19/11/2004 a nonvolatile oily phase. PO Box 4000, Route 206 & Province Line Rd, Filing Date: 19/11/2004 Diazaindole- Dicarbonyl- Bristol-Myers Squibb Company, Warrant signed on 2492 Princeton, New Jersey Rec: 8911/2 dt Wef: 26/11/2003 Vide PT 2492 piperazinyl antiviral agents. Att: Mamo TCV Advocates 02/06/2005 08543-4000, United 30/11/2004 States of America

PO Box 4000, Route 206 & Province Line Rd, Filing Date: 19/11/2004 HMG-COA Reductase Bristol-Myers Squibb Company, Warrant signed on 2493 Princeton, New Jersey Rec: 8908/9 dt Wef: 20/11/2003 Vide PT 2493 inhibitors and Method Att: Mamo TCV Advocates 02/06/2005 08543-4000, United 30/11/2004 States of America

Extended use combination Filing Date: 19/11/2004 Schering Aktiengesellschaft Warrant signed on 2494 comprising estrogens and Berlin 13342, Germany Rec: 8917/8 dt Wef: 26/11/2003 Vide PT 2494 Att: Mamo TCV Advocates 06/05/2005 progestins. 30/11/2004

Prevention and treatment of hypertensive heart disease by the selective estrogens 8beta- Filing Date: 19/11/2004 Schering Aktiengesellschaft Warrant signed on 2495 vinyl-Estra-1,3,5 (10)-Trien-3, Berlin 13342, Germany Rec: 8914/5 dt Wef: 26/11/2003 Vide PT 2495 Att: Mamo TCV Advocates 02/06/2005 17beta-Diol & 17beta-Flour- 30/11/2004 9alpha-vinyl-Estra- 1,3,5(10)trien-3,16alpha-Diol

One Amgen Center Filing Date: 22/11/2004 Gene amplification and Amgen Inc Warrant signed on 2496 Drive, Thousand Oaks, Rec: 8738/9 dt Wef: 24/11/2003 Vide PT 2496 overexpression in cancer. Att: Dr. Maria Chetcuti Cauchi. 02/06/2005 CA 91320-1799, USA 22/11/2004

Salt and crystalline form Bristol-Myers Squibb Filing Date: 23/11/2004 thereof of a corticotropin PO Box 4000 Princeton, Warrant signed on 2497 Pharma Company Rec: 8769/70 dt Wef: 25/11/2003 Vide PT 2497 releasing factor receptor NJ 08543-4000, USA 02/06/2005 Att: SS & Co. 23/11/2004 antagonist.

Processes for the preparation Bristol-Myers Squibb Filing Date: 23/11/2004 of pyrazolo [1,5-a]-1,3,5- PO Box 4000 Princeton, Warrant signed on 2498 Pharma Company Rec: 8766/7 dt Wef: 25/11/2003 Vide PT 2498 Triazines and intermediates NJ 08543-4000, USA 02/06/2005 Att: SS & Co. 23/11/2004 thereof.

4-[(arylmethyl)aminomethyl] Filing Date: 26/11/2004 piperidine derivatives, their Sanofi-Aventis 174 Avenue de France, Warrant signed on 2499 Rec: 8921/2 dt Wef: 01/12/2003 Vide PT 2499 preparation and their Att: SS & Co. FR-75013 Paris, France 21/06/2005 30/11/2004 therapeutic application.

(4-Phenylpiperazine-1-YL) Filing Date: 26/11/2004 acylpiperidine derivatives, Sanofi-Aventis 174 Avenue de France, Warrant signed on 2500 Rec: 8923/4 dt Wef: 01/12/2003 Vide PT 2500 their preparation and their Att: SS & Co. FR-75013 Paris, France 21/06/2005 30/11/2004 therapeutic application. Glaxo Wellcome House, Filing Date: 26/11/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2501 Novel Compounds Rec: 8926/7 dt Wef: 28/11/2003 Vide PT 2501 Att: SS & Co. Greenford Middlesex 02/06/2005 30/11/2004 UB6 ONN, Great Britain

Glaxo Wellcome House, Filing Date: 26/11/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2502 Novel Compounds Rec: 8928/9 dt Wef: 28/11/2003 Vide PT 2502 Att: SS & Co. Greenford Middlesex 02/06/2005 30/11/2004 UB6 ONN, Great Britain

SE - 151 85 Sodertalje, Sweden & 300 Filing Date: 26/11/2004 Astrazeneca AB & Dyax Corp. Warrant signed on 2503 Antibodies. Technology Square, Rec: 8930/1 dt Wef: 28/11/2003 Vide PT 2503 Att: SS & Co. 02/06/2005 Cambridge MA 02139, 30/11/2004 United States of America

In Ovo Vaccination of Eastern Point Road, Filing Date: 30/11/2004 Pfizer Products Inc. Warrant signed on 2505 Campylobacter in Avian Groton, Connecticut Rec: 8899/900 dt Wef: 08/12/2003 Vide PT 2505 Att: SS & Co. 21/06/2005 Species. 06340, USA 30/11/2004

201 Tabor Road, Morris Filing Date: 30/11/2004 Wef: 05/12/2003 N-Alkyl pyrroles as MMG-COA Warner-Lambert Company LLC Warrant signed on 2506 Plains, New Jersey Rec: 8896/7 dt Wef: 16/08/2004 Vide PT 2506 reductase inhibitors. Att: SS & CO 21/06/2005 07950, USA 30/11/2004 Wef: 25/10/2004

Heterocyclic substituted 201 Tabor Road, Morris Filing Date: 30/11/2004 indane derivatives and related Warner-Lambert Company LLC Wef: 08/12/2003 Warrant signed on 2507 Plains, New Jersey Rec: 8893/4 dt Vide PT 2507 compounds for the treatment Att: SS & CO Wef: 19/12/2003 21/06/2005 07950, USA 30/11/2004 of schizophrenia

Glaxo Wellcome House, Filing Date: 30/11/04 Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Warrant signed on 2508 Rec: 8889/90 dt Wef: 03/12/2003 Vide PT 2508 receptor antagonists. Att: SS & Co. Greenford Middlesex 21/06/2005 30/11/2004 UB6 ONN, Great Britain

Glaxo Wellcome House, Novel M3 Muscarinic Glaxo Group Limited Berkeley Avenue, Filing Date: 30/11/2004 Warrant signed on 2509 acetylcholine receptor Wef: 03/12/2003 Vide PT 2509 Att: SS & Co. Greenford Middlesex Rec:8886/7 dt 30/11/2004 21/06/2005 antagonists. UB6 ONN, Great Britain

PO Box 4000, Route 206 Filing Date: 03/12/2004 Heterocyclic anti-migraine Bristol-Myers Squibb Company & Province Line Road, Wef: 05/12/2003 Warrant signed on 2510 Rec: 8973/4 dt Vide PT 2510 agents. Att: MAMO TCV Advocates Princeton, New Jersey, Wef: 03/12/2004 21/06/2005 03/12/2004 USA PO Box 4000, Route 206 Filing Date: 03/12/2004 Calcitonin gene related Bristol-Myers Squibb Company & Province Line Road, Warrant signed on 2511 Rec: 8976/7 dt Wef: 05/12/2003 Vide PT 2511 peptide receptor antagonists. Att: MAMO TCV Advocates Princeton, New Jersey, 21/06/2005 03/12/2004 USA

Memantine for the prevention or reduction of suicidality and 909 Third Avenue, New Filing Date: 06/12/2004 Forest Laboratories Inc. Warrant signed on 2512 for the treatment of major York, NY 10022-4731, Rec: 8990/1 dt Wef: 05/12/2003 Vide PT 2512 Att: Dr. Maria Chetcuti Cauchi 21/06/2005 depression associated with USA 06/12/2004 suicidality.

Novel ligands that activate the 635 route des Lucioles rar receptors, process for Galderma Research & Filing Date: 07/12/2004 06902, BP87 06902 Warrant signed on 2513 preparing them and use Development, S.N.C. Rec: 9023/4 dt Wef: 08/12/2003 Vide PT 2513 Sophia Antipolis Cedex, 21/06/2005 thereof in human medicine Att: SS & CO. 07/12/2004 France and in cosmetics.

Novel ligands that are 635 route des Lucioles Galderma Research & Filing Date: 07/12/2004 activators of the RAR 06902, BP87 06902 Warrant signed on 2514 Development, S.N.C. Rec: 9026/7 dt Wef: 08/12/2003 Vide PT 2514 receptors, use in human Sophia Antipolis Cedex, 21/06/2005 Att: SS & CO. 07/12/2004 medicine and in cosmetics. France

Methods of treating acute Eastern Point Road, Filing Date: 10/12/2004 Pfizer Products Inc. Warrant signed on 2517 inflammation in animals with Groton, Connecticut Rec: 9183/4 dt Wef: 18/12/2003 Vide PT 2517 Att: SS & Co. 06/07/2005 P38 MAP Kinase inhibitors. 06340, USA 16/12/2004

Eastern Point Road, Filing Date: 10/12/2004 Pyrido [2-3-D] Pyrimidine-2,4- Pfizer Products Inc. Warrant signed on 2518 Groton, Connecticut Rec: 9187/8 dt Wef: 16/12/2003 Vide PT 2518 diamines as PPE 2 Inhibitors. Att: SS & Co. 06/07/2005 06340, USA 16/12/2004

New 5,6-Dihydropyridin-2-One- Filing Date: 10/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 18/12/2003 Warrant signed on 2519 Compound useful as Rec: 9190/1 dt Vide PT 2519 Att: SS & Co. Sweden Wef: 25/05/2004 06/07/2005 inhibitors of thrombin 16/12/2004

Filing date 10/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2520 New Compounds. Rec: 9193/4 dt Wef: 18/12/2003 Vide PT 2520 Att: SS & Co. Sweden 06/07/2005 16/12/2004

235 East 42nd Street, Amino Heterocyclyl inhibitors Filing Date: 10/12/2004 Pfizer Inc. New York, New York Wef: 19/12/2003 Warrant signed on 2521 of 11-Beta-Hydroxy steroid Rec: 9196/7 dt Vide PT 2521 Att: SS & Co 10017, United States of Wef: 26/03/2004 06/07/2005 dehydrogenase type 1. 16/12/2004 America Novel compounds which are modulators of the PPAR-type Galderma Research & 635 route des Lucioles, Filing Date: 10/12/2004 Warrant signed on 2522 receptors and their use in Development, S.N.C. BP87 06902 Sophia Rec: 9199/200 dt Wef: 11/12/2003 Vide PT 2522 21/06/2005 cosmetic or pharmaceutical Att: SS & Co. Antipolis Cedex, France 16/12/2004 compounds.

UV-Stable, liquid or semisolid Filing Date: 10/12/2004 transdermal pharmaceutical Schering Aktiengesellschaft Warrant signed on 2523 Berlin 13342, Germany Rec: 9081/2 dt Wef: 10/12/2003 Vide PT 2523 preparation with light Att: MAMO TCV Advocates 06/07/2005 14/12/2004 sensitive active ingredient.

Transdermal delivery of Filing Date: 10/12/2004 Schering Aktiengesellschaft Warrant signed on 2524 hormones without the need of Berlin 13342, Germany Rec: 9084/5 dt Wef: 12/12/2003 Vide PT 2524 Att: MAMO TCV Advocates 19/07/2005 penetration enhancers. 14/12/2004

One Amgen Center Filing Date: 10/12/2004 Anti-Galanin Antibodies and Amgen Inc. Warrant signed on 2525 Drive, Thousand Oaks, Rec: P585344 dt Wef: 10/12/2003 Vide PT 2525 uses thereof. Att: Dr. Maria Chetcuti Cauchi 21/06/2005 CA 91320-1799, USA 14/12/2004

235 East 42nd Street, Filing Date: 14/12/2004 Pfizer Inc. Warrant signed on 2526 Substituted Arylpyrazoles New York, New York Rec: 9212/3 dt Wef: 18/12/2003 Vide PT 2526 Att: SS & Co 06/07/2005 10017, USA. 16/12/2004

Filing Date: 14/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2527 New Compounds. Rec: 9215/6 dt Wef: 22/12/2003 Vide PT 2527 Att: SS & Co. Sweden 06/07/2005 16/12/2004

Filing Date: 14/12/2004 Nicotinic Acetlycholine Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2528 Rec: 9218/9 dt Wef: 22/12/2003 Vide PT 2528 receptor ligands. Att: SS & Co. Sweden 06/07/2005 16/12/2004

235 East 42nd Street, Filing Date: 14/12/2004 Pfizer Inc. Wef: 22/12/2003 Warrant signed on 2529 Compounds useful in therapy. New York, New York Rec: 9221/2 dt Vide PT 2529 Att: SS & Co Wef: 20/04/2004 06/07/2005 10017, USA. 16/12/2004

Filing Date: 14/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2530 Diphenylazetidone derivatives. Rec: 9224/5 dt Wef: 23/12/2003 Vide PT 2530 Att: SS & Co. Sweden 06/07/2005 16/12/2004

174 Avenue de France, Substituted 8¹-Pyri(M1)Dinyl- FR-75013 Paris, France Filing Date: 14/12/2004 Dihydrospiro [cyclo Sanofi-Aventis & Mitsubishi Warrant signed on 2531 & Hiranomachi-2-Chome, Rec: 9227/8 dt Wef: 19/12/2003 Vide PT 2531 Alkylamine]-Pyrimido [1,2-a] - Pharma Corporation 06/07/2005 Chuo-Ku, Osaka-Shi, 16/12/2004 pyrimidin-6-One derivatives. Osaka 541-0046, Japan Filing Date: 14/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 24/12/2003 Warrant signed on 2532 Compounds. Rec: 9230/1 dt Vide PT 2532 Att: SS & Co. Sweden Wef: 28/07/2004 06/07/2005 16/12/2004

Filing Date: 14/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 24/12/2003 Warrant signed on 2533 Compounds. Rec: 9233/4 dt Vide PT 2533 Att: SS & Co. Sweden Wef: 29/07/2004 06/07/2005 16/12/2004

SE - 151 85 Nitrogen-Containing Astrazeneca AB & NPS Sodertalje, Sweden & Filing Date: 14/12/2004 heterocycles affecting Warrant signed on 2534 Pharmaceuticals Inc. 383 Colorow Drive Salt Rec: 9236/7 dt Wef: 19/12/2003 Vide PT 2534 glytamatergic synaptic 06/07/2005 Att: SS & Co. Lake City, UT 84108, 16/12/2004 transmission. United States of America

Filing Date: 14/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2535 Quinazoline Derivatives. Rec: 9239/40 dt Wef: 24/12/2003 Vide PT 2535 Att: SS & Co. Sweden 06/07/2005 16/12/2004

Filing Date: 14/12/2004 Sanofi-Aventis 174 Avenue de France, Warrant signed on 2536 New Compounds. Rec: 9242/3 dt Wef: 22/12/2003 Vide PT 2536 Att: SS& Co. FR - 75013 Paris, France 06/07/2005 16/12/2004

4-Aminopyrimidines as Ronda del General Filing Date: 14/12/2004 Almirall Prodesfarma S.A. Wef: 15/12/2003 Warrant signed on 2537 adenosine receptor Mitre 151, Barcelona Rec: 9115/6 dt Vide PT 2537 Att: MAMO TCV Advocates Wef: 05/10/2004 19/07/2005 antagonists. 08022, Spain 15/12/2004

P.O. Box 4000, Route Azabicyclic heterocycles as Filing Date: 14/12/2004 Bristol-Myers Squibb Company 206 & Province Line Warrant signed on 2539 cannabinoid receptor Rec: 9110/1 dt Wef: 19/12/2004 Vide PT 2539 Att: MAMO TCV Advocates Road, Princeton, New 06/07/2005 modulators. 15/12/2004 Jersey 08543-4000, USA

P.O. Box 4000, Route Azabicyclic heterocycles as Filing Date: 14/12/2004 Bristol-Myers Squibb Company 206 & Province Line Warrant signed on 2540 cannabinoid receptor Rec: 9107/8 dt Wef: 19/12/2003 Vide PT 2540 Att: MAMO TCV Advocates Road, Princeton, New 06/07/2005 modulators. 15/12/2004 Jersey 08543-4000, USA

16711 Trans-Canada Filing Date: 14/12/2004 Merck Frosst Canada & CO Att: Highway, Kirkland Wef: 15/12/2003 2541 Refused wef - no title Rec: 9143/4 dt REFUSED Vide PT 2541 Dr. Maria Chetcuti Cauchi. Quebec, Canada H9H Wef: 06/05/2005 15/12/2004 3LI

Filing Date: 16/12/2004 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2542 Amide Derivatives. Rec: 9203/4 dt Wef: 20/12/2003 Vide PT 2542 Att: SS & Co. Sweden 06/07/2005 16/12/2004

Filing Date: 16/12/2004 Process for the purification of Zambon Group S.p.A. Via della Chimica, 9 Warrant signed on 2543 Rec: 9245/6 dt Rec: 16/12/2003 Vide PT 2543 Gabapeutin Att: SS & Co. 36100 Vicenza, Italy 06/07/2005 16/12/2004 Filing Date: 17/12/2004 3-Cyano-Quinoline derivatives Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2544 Rec: 9252/3 dt Wef: 18/12/2003 Vide PT 2544 with antiproliferative activity Att: Ellul Mifusd & Debono 2340 Beerse, Belgium. 06/07/2005 17/12/2004

Pyrido- and Filing Date: 17/12/2004 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2545 pyrimidopyrimidine Rec: 9255/6 dt Wef: 18/12/2003 Vide PT 2545 Att: Ellul Mifusd & Debono 2340 Beerse, Belgium. 06/07/2005 derivatives. 17/12/2004

New Phenylboronic acid Galderma Research & 635 route des Lucioles, Filing Date: 17/12/2004 Warrant signed on 2546 derivatives and processes for Development, S.N.C. BP87 06902 Sophia Rec: 9259/60 dt Wef: 18/12/2003 Vide PT 2546 07/07/2005 preparing them. Att: SS & CO. Antipolis Cedex, France 17/12/2004

105,Ponce de Leon, One SB Pharmaco Puerto Rico Inc, Comptroller Plaza Hato USA corporations, CSC, The Filing Date: 21/12/2004 CRF Receptor antagonists and Rey, Puerto Rico 00917 Warrant signed on 2547 United States Corporation & Rec: 9324/5 dt Wef: 22/12/2003 Vide PT 2547 methods relating thereto. & 12790 EL Camino 07/07/2005 Neurocrine Biosciences Inc. 22/12/2004 Real, San Diego, CA Att: SS & CO. 92130, USA

235 East 42nd Street, Filing Date: 21/12/2004 Pfizer Inc. New York, New York Warrant signed on 2548 Novel quinoline derivatives. Rec: 9321/2 dt Wef: 23/12/2003 Vide PT 2548 Att: SS & Co. 10017, United States of 07/07/2005 22/12/2004 America

Filing Date: 21/12/2004 Wef: 23/12/2003 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2549 Diphenylazetidone derivatives. Rec: 9318/9 dt Wef: 21/07/2004 Vide PT 2549 Att: SS & Co. Sweden 07/07/2005 22/12/2004 Wef: 15/11/2004

1-Piperazine-and 1- Filing Date: 21/12/2004 homopiperazine-carboxylate Sanofi-Aventis 174 Avenue de France, Warrant signed on 2550 Rec: 9315/6 dt Wef: 23/12/2003 Vide PT 2550 derivatives, preparation and Att: SS & Co. FR-75013 Paris, France 07/07/2005 22/12/2004 therapeutic.

Glaxo Wellcome House, Filing Date: 21/12/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2551 Immunoglobulins. Rec: 9312/3 dt Wef: 22/12/2003 Vide PT 2551 Att: SS & Co. Greenford, Middlesex 07/07/2005 22/12/2004 UB6 ONN, Great Britain

One Amgen Center Filing Date: 22/12/2004 HEH4 Molecules and uses Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2553 Rec: 9395/6 dt Wef: 22/12/2003 Vide PT 2553 thereof. Att: J. Mifsud. California 91320-1799, 07/07/2005 23/12/2004 United States of America

Inhibitors of cyclin-dependent 610 Lincoln Street, Wef: 23/12/2003 GPC Biotech Inc. Filing Date: 22/12/2004 Warrant signed on 2554 Kinases, compositions and Waetham MA 02 451, Wef: 06/04/2004 Vide PT 2554 Att: Dr. Maria Chetcuti Cauchi Rec:9392/3 dt 23/12/2004 07/07/2005 uses related thereto USA Wef: 06/10/2004 One Amgen Center Filing Date: 22/12/2004 Aryl Sulfonamide compounds Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2555 Rec: 9389/90 dt Wef: 22/12/2003 Vide PT 2555 and uses related thereto. Attn: CC Advocates California 91320-1799, 07/07/2005 23/12/2004 USA

6-10 Koishikawa 4- Filing Date: 27/12/2004 1,2-D1(cyclic) substituted Eisai R&D Management Co. Ltd. Wef: 26/12/2003 Warrant signed on 2556 chome, Bunkyo-ku, Rec: 9457/8 dt Vide PT 2556 benzene compounds. Attn: S S & Co. Wef: 26/12/2003 07/07/2005 Tokyo 112-8088, Japan 27/12/2004

A crystalline form of the salt of 4-(3-Cholor-4- (Cyclopropylaminocarbonyl) 6-10 Koishikawa 4- Filing Date: 27/12/2004 Aminophenoxy)-7-Methoxy-6- Eisai R&D Management Co. Ltd. Warrant signed on 2557 chome, Bunkyo-ku, Rec: 9454/5 dt Wef: 25/12/2003 Vide PT 2557 Quinolinecarboxamide or the Attn: S S & Co. 07/07/2005 Tokyo 112-8088, Japan 27/12/2004 solvate of the salt and a process for preparing the same.

2455 Routes des Filing Date: 28/12/2004 Nicox S.A. Dolines, Espace Gaia, 11- Warrant signed on 2558 Prostaglandin derivatives. Rec: 9476/7 dt Wef: 05/01/2004 Vide PT 2558 Att: SS & Co. Batiment, 06906 Sophia 21/07/2005 28/12/2004 Antipolis, France

Filing Date: 28/12/2004 Substituted heterocycles and Astrazeneca AB SE - 151 85 Sodertalje, Wef: 05/01/2004 Warrant signed on 2559 Rec: 9473/4 dt Vide PT 2559 the use thereof. Att: SS & Co. Sweden Wef: 15/03/2004 21/07/2005 28/12/2004

PO Box 4000, Route 206 Filing Date: 29/12/2004 Pyrrolotriazine compounds as Bristol-Myers Squibb Company & Province Line Road, Warrant signed on 2560 Rec: 9486/7 dt Wef: 29/12/2003 Vide PT 2560 Kinase inhibitors. Att: MAMO TCV Advocates Princeton, New Jersey 07/07/2005 29/12/2004 08543-40000, USA

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Warrant signed on 2561 Heterocyclic derivatives. Wef: 08/01/2004 Vide PT 2561 Att: SS & Co. Sweden Rec: 40/1 dt 04/01/2005 21/07/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Wef: 07/01/2004 Warrant signed on 2562 Therapeutic Agents. Vide PT 2562 Att: SS & Co. Sweden Rec: 37/8 dt 04/01/2005 Wef: 16/11/2004 21/07/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Warrant signed on 2563 Therapeutic agents. Wef: 07/01/2004 Vide PT 2563 Att: SS & Co. Sweden Rec: 34/5 dt 04/01/2005 21/07/2005

Diarylmethyl piperazine Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Warrant signed on 2564 derivatives, preparations Wef: 09/01/2004 Vide PT 2564 Att: SS & Co. Sweden Rec: 31/2 dt 04/01/2005 21/07/2005 thereof and uses thereof Diarylmethyl piperazine Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Warrant signed on 2565 derivatives, preparations Wef: 09/01/2004 Vide PT 2565 Att: SS & Co. Sweden Rec: 28/9 dt 04/01/2005 21/07/2005 thereof and uses thereof.

Diarylmethyl piperazine Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 04/01/2005 Warrant signed on 2566 derivatives, preparations Wef: 09/01/2004 Vide PT 2566 Att: SS & Co. Sweden Rec: 25/6 dt 04/01/2005 21/07/2005 thereof and uses thereof.

Trisubstituted aryl and heteroaryl derivatives as 6166 Nancy Ridge Drive, Arena Pharmaceuticals, Inc. Filing Date: 06/01/2005 Warrant signed on 2567 modulators of metabolism and San Diego, California Wef: N/A Vide PT 2567 Att: Dr. Maria Chetcuti Cauchi Rec: 73/4 dt 06/01/2005 19/07/2006 the prophylaxis and treatment 92121,USA of disorders related thereto.

Fused-Aryl and heteroaryl derivatives as modulators of 6166 Nancy Ridge Drive, Filing Date: 07/01/2005 Arena Pharmaceuticals, Inc. Warrant signed on 2568 metabolism and the San Diego, California Rec: P585349 dt Wef: N/A Vide PT 2568 Att: Dr. Maria Chetcuti Cauchi 19/07/2006 prophylaxis and treatment of 92121,USA 07/01/2005 disorders related thereto.

N - [(1,5-Diphenyl-1H-Pyrazol-3- YL) Methyl] Sulphonamide Sanofi-Aventis 174 Avenue de France, Filing Date: 07/01/2005 Warrant signed on 2569 derivatives, preparation and Rec: 12/01/2004 Vide PT 2569 Att: SS & Co. FR-75013 Paris, France Rec: 85/4 dt 10/01/2005 21/07/2005 therapeutic application thereof.

235 East 42nd Street, New York, 10017 New York, United States of Pfizer Inc. & Abgenix Inc. Filing Date: 07/01/2005 Warrant signed on 2570 Antibodies to madcam America & 6701 Kaiser Rec: 09/01/2004 Vide PT 2570 Att: SS & Co. Rec: 86/7 dt 10/01/2005 21/07/2005 Drive, Fremont, 94555, California, United States of America

Crystalline forms of rizatriptan Ratiopharm GmbH Graf-Arco-Str 3, D-89079 Filing Date: 10/01/2005 Warrant signed on 2571 Rec: 01/09/2004 Vide PT 2571 benzoate Att: J.Mifsud. Ulm, Germany Rec: 114/5 dt 10/01/2005 21/07/2005

Acylaminothiazole derivatives, Sanofi-Aventis 174 Avenue de France, Filing Date: 11/01/2005 Wef: 16/01/2004 Warrant signed on 2572 preparation and therapeutic Vide PT 2572 Att: SS & Co. FR-75013 Paris, France Rec: 144/5 dt 11/01/2005 Wef: 22/07/2004 04/08/2005 application thereof.

Aryloxyalkylcarbamate-type derivatives, their preparation Sanofi-Aventis 174 Avenue de France, Filing Date: 11/1/2005 Warrant signed on 2573 Wef: 16/01/2004 Vide PT 2573 and their application in Att: SS & Co. FR-75013 Paris, France Rec: 147/8 - 11/01/2005 04/08/2005 therapy. Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 11/01/2005 Wef: 13/01/2004 2574 Compounds WITHDRAWN Vide PT 2574 Att: SS & Co. Greenford, Middlesex Rec: 150/1 dt 11/01/2005 Wef: 18/11/2004 UB6 ONN, Great Britain

Acylaminothiazole derivatives, Sanofi-Aventis 174 Avenue de France, Filing Date: 11/01/2005 Wef: 16/01/2004 Warrant signed on 2575 their preparation and their Vide PT 2575 Att: SS & Co. FR-75013 Paris, France Rec: 153/4 dt 11/01/2005 Wef: 22/07/2004 04/08/2005 therapeutic application.

PO Box 4000, Route 206 Heterocyclic compounds Bristol-Myers Squibb Company & Province Line Road, Filing Date: 13/01/2005 Warrant signed on 2576 useful as growth hormone Wef: 13/01/2004 Vide PT 2576 Att: MAMO TCV Advocates Princeton, New Jersey Rec: 205/6 dt 13/01/2005 21/07/2005 secretagogues. 08543-4000, USA

Susbtituted heterocyclic One Amgen Center Amgen Inc. Filing Date: 14/01/2005 Wef: 14/01/2004 Warrant signed on 2577 compounds and methods of Drive, Thousand Oaks, Vide PT 2577 Att: Dr. Maria Chetcuti Cauchi. Rec: 223/4 dt 14/01/2005 Wef: 11/01/2005 01/09/2005 use. CA 91320-1799, USA

Diaryl and aryltieteroaryl urea derivatives as modulators of 6166 Nancy Ridge Drive, the 5-HT2A serotonin receptor Arena Pharmaceuticals Inc. Filing Date: 14/01/2005 Warrant signed on 2578 San Diego, California Wef: N/A Vide PT 2578 useful for the prophylaxis and Att: Dr. Maria Chetcuti Cauchi Rec: 227/8 dt 14/01/2005 21/07/2006 92121, USA treatment of disorders related thereto.

Acylaminothiozole derivatives, Sanofi-Aventis 174 Avenue de France, Filing Date: 14/01/2005 Wef: 16/01/2004 2579 their preparation and their WITHDRAWN Vide PT 2579 Att: SS & Co. FR-75013 Paris, France Rec: 236/7 dt 14/01/2005 Wef: 27/07/2004 therapeutic application

Tricyclic modulators of the PO Box 4000, Route 206 glucocorticoid receptor, AP-1, Bristol-Myers Squibb Company & Province Line Road, Filing Date: 14/01/2005 Warrant signed on 2580 Wef: 16/01/2004 Vide PT 2580 and/or NF-KB activity and use Att: MAMO TCV Advocates Princeton, New Jersey Rec: 245/6 dt 14/01/2005 04/08/2005 thereof. 08543-4000, USA

Heterocyclic modulators of the PO Box 4000, Route 206 glucocorticoid receptor; Ap-1, Bristol-Myers Squibb Company & Province Line Road, Filing Date: 14/01/2005 Warrant signed on 2581 Wef: 16/01/2004 Vide PT 2581 and/or NF-KB activity and use Att: MAMO TCV Advocates Princeton, New Jersey Rec: 248/9 dt 14/01/2005 04/08/2005 thereof. 08543-4000, USA Modulators of the PO Box 4000, Route 206 glucocorticoid receptor, AP-1, Bristol-Myers Squibb Company & Province Line Road, Filing Date: 14/01/2005 Warrant signed on 2582 Wef: 10/01/2004 Vide PT 2582 and/or NF-KB activity and use Att: MAMO TCV Advocates Princeton, New Jersey Rec: 251/2 dt 14/01/2005 24/08/2005 thereof 08543-4000, USA

Modulators of the PO Box 4000, Route 206 glucocorticoid receptor, AP-1, Bristol-Myers Squibb Company & Province Line Road, Filing Date: 14/01/2005 Wef: 16/01/2004 Warrant signed on 2583 Vide PT 2583 and/or NF-KB activity and use Att: MAMO TCV Advocates Princeton, New Jersey Rec: 254/5 dt 14/01/2005 Wef: 13/01/2005 04/08/2005 thereof. 08543-4000, USA

Modulators of the PO Box 4000, Route 206 glucocorticoid receptor, AP-1, Bristol-Myers Squibb Company & Province Line Road, Filing Date: 14/01/2005 Wef: 16/01/2004 Warrant signed on 2584 Vide PT 2584 and/or NF-KB activity and use Att: MAMO TCV Advocates Princeton, New Jersey Rec: 257/8 dt 14/01/2005 Wef: 13/01/2005 04/08/2005 thereof. 08543-4000, USA

235 East 42nd Street, Wef: 22/01/2004 Sulfonamide derivatives for Pfizer Inc. Filing Date: 18/01/2005 Warrant signed on 2585 New York, New York Wef: 22/03/2004 Vide PT 2585 the treatment of diseases. Att: SS & Co Rec: 311/2 dt 18/01/2005 04/08/2005 10017, USA. Wef: 09/08/2004

235 East 42nd Street, Wef: 22/01/2004 Sulfonamide derivatives for Pfizer Inc. Filing Date: 18/01/2005 Warrant signed on 2586 New York, New York Wef: 22/03/2004 Vide PT 2586 the treatment of diseases. Att: SS & Co Rec: 308/9 dt 18/01/2005 04/08/2005 10017, USA. Wef: 09/08/2004

126 East Lincoln Avenue, Hydroisoindoline tackykinin Merck & Co Inc. Filing Date: 18/01/2005 Wef: 27/01/2004 Warrant signed on 2587 Railway, New Jersey Vide PT 2587 receptor antagonists. Att: Dr. Maria Chetcuti Cauchi. Rec: 317/8 dt 18/01/2005 Wef: 09/04/2004 04/08/2005 07065, USA

Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 19/01/2005 Warrant signed on 2588 Mitratapide oral solution. Wef: 210/1/2004 Vide PT 2588 Att: EMD Advocates 2340 Beerse, Belgium Rec: 338/9 dt 20/01/2005 04/08/2005

New ondansetron polimorphic forms, process for their preparation, pharmaceutical Vita Cientifica S.L Av. Barcelona, 69, 08970 Filing Date: 21/01/2005 Warrant signed on 2589 Wef: 21/01/2004 Vide PT 2589 compositions containing them Att: SS & Co. Sant Joan, Despi, Spain Rec: 368/9 dt 21/01/2005 04/08/2005 and their use as antiemetic agents.

PO Box 4000, Route 206 Amino-benzazoles as P2Y1 Bristol-Myers Squibb Company & Province Line Road, Filing Date: 21/01/2005 Wef: 21/01/2004 Warrant signed on 2590 Vide PT 2590 receptor inhibitors. Att: MAMO TCV Advocates Princeton, New Jersey Rec: 388/9 dt 21/01/2005 Wef: 22/12/2004 04/08/2005 08543-4000, USA Hertford Road, Polymorphic forms of a Merck Sharp & Dohme Limited Hoddesdon, Filing Date: 21/01/2005 Warrant signed on 2591 Wef: 30/01/2004 Vide PT 2591 GABAa agonist Att: Dr. Maria Chetcuti Cauchi Hertfordshire EN 11 9 Rec: 391/2 dt 21/01/2005 04/08/2005 BO, United Kingdom.

One Amgen Center Vanilloid receptor ligands and Amgen Inc. Filing Date: 24/01/2005 Wef: 23/01/2004 Warrant signed on 2592 Drive, Thousand Oaks, Vide PT 2592 their use in treatments Att: Dr. Maria Chetcuti Cauchi Rec: 404/5 dt 24/01/2005 Wef: 21/01//2005 04/08/2005 CA 91320-1799, USA

One Amgen Center Vanilloid receptor ligands and Amgen Inc. Filing Date: 24/01/2005 Wef: 23/01/2004 Warrant signed on 2593 Drive, Thousand Oaks, Vide PT 2593 their use in treatments. Att: Dr. Maria Chetcuti Cauchi Rec: 407/8 dt 24/01/2005 Wef: 21/01//2005 31/10/2005 CA 91320-1799, USA

One Amgen Center Vanilloid receptor ligands and Amgen Inc. Filing Date: 24/01/2005 Wef: 23/01/2004 Warrant signed on 2594 Drive, Thousand Oaks, Vide PT 2594 their use in treatments. Att: Dr. Maria Chetcuti Cauchi Rec: 410/1 dt 24/01/2005 Wef: 21/01/2005 01/09/2005 CA 91320-1799, USA

One Amgen Center Vanilloid receptor ligands and Amgen Inc. Filing Date: 24/01/2005 Wef: 23/01/2004 Warrant signed on 2595 Drive, Thousand Oaks, Vide PT 2595 their use in treatments. Att: Dr. Maria Chetcuti Cauchi Rec: 413/4 dt 24/01/2005 Wef: 21/01//2005 01/09/2005 CA 91320-1799, USA

Substituted heterocyclic One Amgen Center Amgen Inc. Filing Date: 24/01/2005 Wef: 22/01/2004 Warrant signed on 2596 compounds and Methods of Drive, Thousand Oaks, Vide PT 2596 Att: Dr. Maria Chetcuti Cauchi Rec: 417/8 dt 24/01/2005 Wef: 21/01//2005 01/09/2005 use. CA 91320-1799, USA

One Amgen Center Filing Date: 24/01/2005 Compounds and Methods of Amgen Inc. Warrant signed on 2597 Drive, Thousand Oaks, Rec: 439/40 dt Wef: 23/01/2004 Vide PT 2597 use. Att: Mr J.Mifsud 04/08/2005 CA 91320-1799, USA 25/01/2005

One Amgen Center Compounds and Methods of Amgen Inc. Filing Date: 24/01/2005 Warrant signed on 2598 Drive, Thousand Oaks, Wef: 23/01/2004 Vide PT 2598 use. Att: Mr J.Mifsud Rec: 436/7 dt 25/01/2005 04/08/2005 CA 91320-1799, USA

Eastern Point Road, NK-1 receptor antagonists to Pfizer Products Inc. Filing Date: 25/01/2005 Warrant signed on 2599 Groton, Connecticut Wef: 30/01/2004 Vide PT 2599 improve anesthesia recovery Att: SS & Co. Rec: 464/5 dt 25/01/2005 04/08/2005 06340, USA

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 25/01/2005 Warrant signed on 2600 Quinazoline derivatives. Wef: 08/02/2004 Vide PT 2600 Att: SS & Co. Sweden Rec: 461/2 dt 25/01/2005 01/09/2005 Pharmaceutical compositions of neurokinin receptor Eastern Point Road, Filing Date: 25/01/2005 Pfizer Products Inc. Warrant signed on 2601 antagonists and cyclo dextrin Groton, Connecticut Rec: 2459/60 dt Wef: 30/01/2004 Vide PT 2601 Att: SS & Co. 04/08/2005 and Methods for improved 06340, USA 25/01/2005 injection site toleration.

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 25/01/2005 Wef: 03/02/2004 Warrant signed on 2602 Chemical Compounds. Vide PT 2602 Att: SS & Co. Sweden Rec: 456/7 dt 25/01/2005 Wef: 28/05/2004 01/09/2005 MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 25/01/2005 Warrant signed on 2603 Chemical compounds Wef: 02/02/2004 Vide PT 2603 Att: SS & Co. Sweden Rec: 453/4 dt 25/01/2005 01/09/2005

Synthesis Methods and Ratiopharm Gmbh Graf-Arco- Str 3, D- Filing Date: 27/01/2005 Wef: 28/01/2004 Warrant signed on 2604 Intermediates for the Vide PT 2604 Att: J. Mifsud 89079 Ulm, Germany Rec: 531/2 dt 27/01/2005 Wef: 10/02/2004 04/08/2005 manufacture of rizatriptan

HCV NS-3 Serine protease Medivir AB Lunastigen 7, 141 44 Filing Date: 28/01/2005 Warrant signed on 2605 Wef: 30/01/2004 Vide PT 2605 inhibitors Att: EMD Advocates Huddinge, Sweden Rec: 560/1 dt 28/01/2005 04/08/2005

HCV NS-3 Serine protease Medivir AB Lunastigen 7, 141 44 Filing Date: 28/01/2005 Warrant signed on 2606 Wef: 30/01/2004 Vide PT 2606 inhibitors Att: EMD Advocates Huddinge, Sweden Rec: 563/4 dt 28/01/2005 04/08/2005

235 East 42nd Street, Wef: 04/02/2004 Pharmaceutically active Pfizer Inc. New York, New York Filing Date: 01/02/2005 Warrant signed on 2607 Wef: 03/06/2004 Vide PT 2607 compounds Att: SS & Co. 10017, United States of Rec: 728/9 dt 07/02/2005 01/09/2005 Wef: 19/11/2004 America

235 East 42nd Street, Substituted quinoline Pfizer Inc. New York, New York Filing Date: 01/02/2005 Wef: 04/02/2004 Warrant signed on 2608 Vide PT 2608 compounds Att: SS & Co. 10017, United States of Rec: 731/2 dt 07/02/2005 Wef: 06/12/2004 01/09/2005 America

1H - Thieno [2,3-C] pyrazole Pharmacia Italia SpA Via Robert Kock 12, Filing Date: 01/02/2005 Warrant signed on 2609 derivatives useful as kinase Wef: 03/02/2004 Vide PT 2609 Att: SS & Co. 20152 Milan, Italy Rec: 734/5 dt 07/02/2005 01/09/2005 inhibitors

Process for preparation of Eastern Point Road, 1(2S 3S) - 2 - benzhydryl - N - Pfizer Products Inc. Groton, Connecticut Filing Date: 01/02/2005 Warrant signed on 2610 (S - Tert - butyl 2 - Wef: 02/02/2004 Vide PT 2610 Att: SS & Co. 06340, United States of Rec: 737/8 dt 07/02/2005 01/09/2005 methoxybenzyl) quinuclidin - America 3 - amine

New pyridin - 2 - One Filing Date: 01/02/2005 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 06/02/2004 Warrant signed on 2611 compounds useful as Rec: 1739/40 dt Vide PT 2611 Att: SS & Co. Sweden Wef: 24/06/2004 01/09/2005 inhibitors of thrombin 07/02/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 01/02/2005 Warrant signed on 2612 Novel Compounds Wef: 10/02/2004 Vide PT 2612 Att: SS & Co. Sweden Rec: 741/2 dt 07/02/2005 01/09/2005 P.O Box 4000, Route Sulfonylpyrrolidine 206 & Province Line Bristol-Myers Squibb modulators or androgen Road, Princeton, New Filing Date: 03/02/2005 Warrant signed on 2613 Company Wef: 04/02/2004 Vide PT 2613 receptor function and Jersey 08543-4000, Rec: 700/1 dt 07/02/2005 01/09/2005 Att: MAMO TCV Advocates method United States of America

P.O Box 4000, Route Process for preparing 2 - 206 & Province Line Bristol-Myers Squibb aminothiazole - 5 - aromatic Road, Princeton, New Filing Date: 03/02/2005 Wef: 06/02/2004 Warrant signed on 2614 Company Vide PT 2614 carboxamide as kinase Jersey 08543-4000, Rec: 704/5 dt 07/02/2005 Wef: 04/11/2004 01/09/2005 Att: MAMO TCV Advocates inhibitors United States of America

901, Gateway Idazole-carboxamide Boulevard, South San Theravance Inc. Filing Date: 08/02/2005 Warrant signed on 2615 compound as S-HT4 Francisco, CA94080 Wef: 18/2/2004 Vide PT 2615 Att: SS & Co. Rec: 772/3 dt 08/02/2005 01/09/2005 receptor agonists United States of America

201 Tabor Road, Morris Androgen receptor Warner-Lambert Company Filing Date: 08/02/2005 Wef: 13/02/2004 Warrant signed on 2616 Plains, New Jersey Vide PT 2616 modulators LLC Att: SS & Co. Rec: 775/6 dt 08/02/2005 Wef: 30/08/2004 01/09/2005 07950, USA

One Franklin Plaza, Smithkline Beecham P.O. Box 7929 Wef: 14/02/2004 Filing Date: 01/02/2005 Warrant signed on 2618 Novel compounds Corporation Philadelphia, PA Wef: 22/10/2004 Vide PT 2618 Rec: 816/7 dt 14/02/2005 01/09/2005 Att: SS & Co. 19101, United States of Wef: 24/12/2004 America

Oxazole derivatives, Filing Date: 11/02/2005 Sanofi - Aventis 174 Avenue de France, Wef: 14/02/2004 Warrant signed on 2619 preparation thereof and use Rec: 819/20 dt Vide PT 2619 Att: SS & Co. FR-75013 Paris, France Wef: 13/02/2004 31/10/2005 thereof in therapeutics 14/02/2005

One Amgen Center Vanilloid receptor ligands Amgen Inc. Drive, Thousand Oaks, Filing Date: 11/02/2005 Warrant signed on 2620 Wef: 11/02/2004 Vide PT 2620 and their use in treatments Att: Chetcuti Cauchi Advocates California 91320-1799, Rec: 821/2 dt 14/02/2005 01/09/2005 USA

One Amgen Center Vanilloid receptor ligands Amgen Inc. Drive, Thousand Oaks, Filing Date: 11/02/2005 Warrant signed on 2621 Wef: 11/02/2004 Vide PT 2621 and their use in treatments Att: Chetcuti Cauchi Advocates California 91320-1799, Rec: 824/5 dt 14/02/2005 01/09/2005 USA

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/02/2005 Wef: 18/02/2004 Warrant signed on 2622 Compounds Vide PT 2622 Att: SS & Co. Sweden Rec: 930/1 dt 15/02/2005 Wef: 16/06/2004 01/09/2005 Wef: 18/02/2004 Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/02/2005 Warrant signed on 2623 Compounds Wef: 16/06/2004 Vide PT 2623 Att: SS & Co. Sweden Rec: 927/8 dt 15/02/2005 01/09/2005 Wef: 16/10/2004

Eastern Point Road, Tetrahydroisoquinolinyl Pfizer Products Inc. Groton, Connecticut Filing Date: 15/02/2005 Warrant signed on 2624 derivatives of quinzoline Wef: 18/02/2004 Vide PT 2624 Att: SS & Co. 06340, United States of Rec: 924/5 dt 15/02/2005 01/09/2005 and isoquinoline America

SE - 151 85 Sodertalje, Astrazeneca AB & Sweden & 383 Colorow Filing Date: 15/02/2005 Warrant signed on 2625 New compounds NPS Pharmaceuticals Inc. Wef: 20/02/2004 Vide PT 2625 Drive, Salt Lake City Rec: 922/3 dt 15/02/2005 01/09/2005 Att: SS & Co. ULT84108, USA

Filing Date: 15/02/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2626 Chemical Compounds Rec: 919/20 dt Wef: 20/02/2004 Vide PT 2626 Att: SS & Co. Sweden 01/09/2005 15/02/2005

Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/02/2005 Wef: 20/02/2004 Warrant signed on 2627 Therapeutic agents Vide PT 2627 Att: SS & Co. Sweden Rec: 916/7 dt 15/02/2005 Wef: 18/09/2004 01/09/2005

Additional heteropolycyclic compounds and their use Astrazeneca AB SE - 151 85 Sodertalje, Filing Date: 15/02/2005 Warrant signed on 2628 Wef: 18/02/2004 Vide PT 2628 as metabotropic glutamate Att: SS & Co. Sweden Rec: 913/4 dt 15/02/2005 01/09/2005 receptor antagonists

Triazole compounds and SE - 151 85 Sodertalje, Astrazeneca AB & their use as metabotropic Sweden & 383 Colorow Filing Date: 15/02/2005 Warrant signed on 2629 NPS Pharmaceuticals Inc. Wef: 18/02/2004 Vide PT 2629 glutamate receptor Drive, Salt Lake City Rec: 910/1 dt 15/02/2005 24/10/2005 Att: SS & Co. antagonists ULT84108, USA

Substituted pyrazoline Ar. Marc de Deu de Laboratorios del Dr Esteve compounds, their Monteserrat, 221 E- Filing Date: 17/02/2005 Wef: 17/02/2004 Warrant signed on 2630 S.A. Att: J Vide PT 2630 preparation and use as 08041, Barcelona, Rec: 974/5 dt 18/02/2005 Wef: 19/03/2004 01/09/2005 Mifsud medicaments Spain

Compression - coated 4th Floor, 7 Carendion Filing Date: 18/02/2005 Arrow No 7 Limited Warrant signed on 2631 tablets and manufacture Square, London WC1 Rec: 1003/4 dt Wef: 18/02/2004 Vide PT 2631 Att: S S & Co 01/09/2005 thereof OPE, England 18/02/2005

Acetlylinic piperazine SE - 151 85 Sodertalje, Astrazeneca AB & compounds and their use Sweden & 383 Colorow Filing Date: 18/02/2005 Warrant signed on 2632 NPS Pharmaceuticals Inc. Wef: 18/02/2004 Vide PT 2632 as metabotropic glutamate Drive, Salt Lake City Rec: 430 dt 19/01/2007 24/10/2005 Att: SS & Co. receptor antagonists ULT84108, USA Fused heterocyclic SE - 151 85 Sodertalje, Astrazeneca AB & compounds and their use Sweden & 383 Colorow Filing Date: 18/02/2005 Warrant signed on 2633 NPS Pharmaceuticals Inc. Wef: 19/02/2004 Vide PT 2633 as metabotropic glutamate Drive, Salt Lake City Rec: 997/8 dt 18/02/2005 01/09/2005 Att: SS & Co. receptor antagonists ULT84108, USA

Tetrazole compounds and SE - 151 85 Sodertalje, Astrazeneca AB & their use as metabotropic Sweden & 383 Colorow Filing Date: 18/02/2005 Warrant signed on 2634 NPS Pharmaceuticals Inc. Wef: 18/02/2004 Vide PT 2634 glutamate receptor Drive, Salt Lake City Rec: 994/5 dt 18/02/2005 01/09/2005 Att: SS & Co. antagonists ULT84108, USA

Polyheterocyclic SE - 151 85 Sodertalje, Astrazeneca AB & compounds and their use Sweden & 383 Colorow Filing Date: 18/02/2005 Warrant signed on 2635 NPS Pharmaceuticals Inc. Wef: 18/02/2004 Vide PT 2635 as metabotropic glutamate Drive, Salt Lake City Rec: 991/2 dt 18/02/2005 24/10/2005 Att: SS & Co. receptor antagonists ULT84108, USA

Methods for treating Frannhoferstrabe 20 Filing Date: 18/02/2005 GPC Biotech AG Warrant signed on 2636 resistant or refractory 82/S2 Martinsreid, Rec: 1009/10 dt Wef: 18/02/2004 Vide PT 2636 Att: Dr. M. Chetcuti Cauchi 01/09/2005 tumors Munich, Germany 18/02/2005

Pharmacologically Siegfried Generics Filing Date: 21/02/2005 Untere Bruhlstasse 4, Warrant signed on 2637 acceptable salts of International AG Rec: 1308/9 dt Wef: 24/02/2004 Vide PT 2637 Zofingen, Switzerland 01/09/2005 dopidogrel Att: MAMO TCV Advocates 04/03/2005

Piperazine urea derivatives Filing Date: 21/02/2005 Schering Aktiengesellschaft Warrant signed on 2638 for the treatment of Berlin 13342, Germany Rec: 1311/2 dt Wef: 24/02/2004 Vide PT 2638 Attn: MAMO TCV Advocates 01/09/2005 endometriosis 04/03/2005

Glaxo Wellcome House, Filing Date: 22/02/2005 Wef: 23/02/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2639 Compounds Rec: 1048/9 dt Wef: 24/02/2004 Vide PT 2639 Att: SS & Co. Greenford, Middlesex 01/09/2005 22/02/2005 Wef: 30/07/2004 UB6 ONN, Great Britain

Tetracyclic fused 2-1 Toranomon 2- Filing Date: 22/02/2005 Wef: 24/02/2004 heterocyclic compound and Japan Tobacco Inc. Warrant signed on 2640 Chome, Murato-Ku, Rec: 1055/6 dt Wef: 07/06/2004 Vide PT 2640 use thereof as HCT Att: SS & Co. 01/09/2005 Tokyo, 105-842, Japan 22/02/2005 Wef: 08/10/2004 polymerase inhibitor

Aryl-and heteroarylpiperidinecarbam Filing Date: 25/02/2005 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2641 ate derivatives, their Rec: 1149/50 dt Wef: 26/02/2004 Vide PT 2641 Att: SS & Co. FR-75013 Paris, France 01/09/2005 preparation and their 02/03/2005 application in therapeutics Aryl-and heteroarylpiperidinecarboxy Sanofi - Aventis 174 Avenue de France, Filing Date: 25/02/2005 Warrant signed on 2642 late derivatives, their Wef: 26/02/2004 Vide PT 2642 Att: SS & Co. FR-75013 Paris, France Rec: 425 dt 19/01/2007 01/09/2005 preparation and their application in therapeutics

Alkylpiperazine - and alkylhomopiperazine- Filing Date: 25/02/2005 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2643 carboxylate derivatives, Rec: 1155/7 dt Wef: 26/02/2004 Vide PT 2643 Att: SS & Co. FR-75013 Paris, France 01/09/2005 their preparation and their 21/03/2005 application in therapeutics

Piperidinylalkylcarbomate Filing Date: 25/02/2005 derivatives, their Sanofi - Aventis 174 Avenue de France, Warrant signed on 2644 Rec: 1152/3 dt Wef: 26/02/2004 Vide PT 2644 preparation and their Att: SS & Co. FR-75013 Paris, France 01/09/2005 02/03/2005 aplication in therapy

Tetrahydroquinolinones and 100 Eckenheimer Merz Pharma GmbH & Co. Filing Date: 25/02/2005 their use as antagonists of Landstrasse, D - 60318 Warrant signed on 2645 KGAA Rec: 5853/60 dt Wef: 27/02/2004 Vide PT 2645 metabotropic glutamate Frankfurt Main, 01/09/2005 Att: Dr. Maria Chetcuti-Cauchi 25/02/2005 receptors Germany

Eisai R&D Management Co. 6-10 Koishikawa 4- Filing Date: 28/02/2005 Novel pyridine derivative Wef: 27/02/2004 Warrant signed on 2646 Ltd. Att: chome, Bunkyo-ku, Rec: 1143/4 dt Vide PT 2646 and pyrimidine derivative Wef: 22/12/2004 01/09/2005 SS & Co. Tokyo 112-8088, Japan 02/03/2005

Compounds, pharmaceutical One Amgen Center Filing Date: 28/02/2005 Amgen Inc Wef: 27/02/2004 Warrant signed on 2648 compositions and methods Drive, Thousand Oaks, Rec: 1102/3 dt Vide PT 2648 Att: J. Mifsud Wef: 12/08/2004 09/09/2005 for use in treating metabolic CA 91320-1799, USA 02/03/2005 disorders

Therapy using 1- aminocyclohexane 100 Eckenheimer Merz Pharma GmbH & Co. Filing Date: 03/03/2005 derivatives for the treatment Landstrasse, D - 60318 Warrant signed on 2649 KGAA Rec: 1244/5 dt Wef: 03/03/2004 Vide PT 2649 of behavioral disorders Frankfurt Main, 31/10/2005 Att: Dr. Maria Chetcuti-Cauchi 03/03/2005 associated with alzheimer's Germany disease

901, Gateway Biphenyl compounds as Filing Date: 03/03/2005 Theravance Inc Boulevard, South San Warrant signed on 2650 muscarinic receptor Rec: 1276/7 dt Wef: 11/03/2004 Vide PT 2650 Att: SS & CO. Francisco, CA 94080, 31/10/2005 antagonists 03/03/2005 USA 901, Gateway Biphenyl compounds as Filing Date: 03/03/2005 Theravance Inc Boulevard, South San Warrant signed on 2651 muscarinic receptor Rec: 1273/4 dt Wef: 11/03/2004 Vide PT 2651 Att: SS & CO. Francisco, CA 94080, 31/10/2005 antagonists 03/03/2005 USA

Substituted heteroaryl and Eastern Point Road, Filing Date: 03/03/2005 Pfizer Products Inc. Wef: 10//03/2004 Warrant signed on 2653 phenylsulfamoyl Groton, Connecticut Rec: 1256/7 dt Vide PT 2653 Att: SS & Co. Wef: 16/12/2004 31/10/2005 compounds 06340, U.S.A. 03/03/2005

Radiohalogenated Patentabteilung, Filing Date: 03/03/2005 benzamide derivatives and Schering AG Warrant signed on 2654 MullerstraBe 170 - 178, Rec: 1818/9 dt Wef: 10/03/2004 Vide PT 2654 their use in tumor diagnosis Att: Mamo TCV 31/10/2005 Berlin 13342, Germany 15/03/2005 and tumor therapy

P.O. Box 4000, Route Novel bicyclic compounds Bristol-Myers Squibb 206 & Province Line Filing Date: 03/03/2005 as modulators of androgen Warrant signed on 2655 Company Road, Princeton, Rec: 1803/4 dt Wef: 04/03/2004 Vide PT 2655 receptor function and 31/10/2005 Attn: MAMO TCV Advocates New Jersey 08543- 15/03/2005 method 4000, U.S.A.

P.O. Box 4000, Route Bristol-Myers Squibb 206 & Province Line Filing Date: 03/03/2005 Bicyclic modulators of Warrant signed on 2656 Company Road, Princeton, Rec: 1805/6 dt Wef: 04/03/2004 Vide PT 2656 androgen receptor function 31/10/2005 Attn: MAMO TCV Advocates New Jersey 08543- 15/03/2005 4000, U.S.A.

P.O. Box 4000, Route Novel bicyclic compounds Bristol-Myers Squibb 206 & Province Line Filing date: 03/03/2005 as modulators of androgen Warrant signed on 2657 Company Road, Princeton, Rec: 1807/8 dt Wef: 04/03/2004 Vide PT 2657 receptor function and 31/10/2005 Attn: MAMO TCV Advocates New Jersey 08543- 15/03/2005 method 4000, U.S.A.

MTP inhibiting aryl Janssen Pharmaceutica NV Filing Date: 08/03/2005 piperidines or piperazines Turnhoutseweg 30, B- Warrant signed on 2658 Att: Ellul Mifsud & Debono Rec: P585368 dt Wef: 10/03/2004 Vide PT 2658 substituted with 5 - 2340 Beerse, Belgium 31/10/2005 Advocates 08/03/2005 membered heterocycles

1120 Veterans Boulevard South San Francisco, California Amgen SF, LLC 94080, United States of Filing Date: 08/03/2005 Therapeutic modulation of Warrant signed on 2659 Amgen Inc America & One Amgen Rec: P585370 dt Wef: 08/03/2004 Vide PT 2659 PPARy activity 31/10/2005 Att: Dr M Chetcuti Cauchi Center Drive, 08/03/2005 Thousand Oaks, California 91320, United States of America Stabilised supersaturated Schering Aktiengesellschaft Mullerstrasse 178, Filing Date: 08/03/2005 Warrant signed on 2660 Wef: 10/03/2004 Vide PT 2660 solids of lipophilic drugs Att: Mamo TCV Advocates Berlin 13342, Germany Rec:1794 dt 15/03/2005 31/10/2005

Filing Date: 08/03/2005 Molecular dispersions of Schering Aktiengesellschaft Mullerstrasse 178, Warrant signed on 2661 Rec: 1799/800 dt Wef: 10/03/2004 Vide PT 2661 drospirenone Att: Mamo TCV Advocates Berlin 13342, Germany 31/10/2005 15/03/2005

980, Great West Road, Filing Date: 10/03/2005 Pharmaceutical SmithKline Beecham plc Warrant signed on 2662 Brentford, Middlesex Rec: 1574/5 dt Wef: 12/03/2004 Vide PT 2662 formulations Att: SS & Co 31/10/2005 YW8 9GS, England 11/03/2005

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 15/03/2005 Muscarinic acetylcholine Glaxo Group Limited Warrant signed on 2664 Greenford Rec: 1901/2 dt Wef: 17/03/2004 Vide PT 2664 receptor antagonists Att: SS & Co. 31/10/2005 Middlesex UB6 ONN, 16/03/2005 Great Britain

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 15/03/2005 M3 muscarinic acetylcholine Glaxo Group Limited Warrant signed on 2665 Greenford Rec :1898/9 dt Wef: 17/03/2004 Vide PT 2665 receptor antagonists Att: SS & Co. 31/10/2005 Middlesex UB6 ONN, 16/03/2005 Great Britain

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 15/03/2005 M3 muscarinic acetylcholine Glaxo Group Limited Warrant signed on 2666 Greenford Rec: 1895/6 dt Wef: 17/03/2005 Vide PT 2666 receptor antagonists Att: SS & Co. 31/10/2005 Middlesex UB6 ONN, 16/03/2005 Great Britain

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 15/03/2005 M3 muscarinic acetylcholine Glaxo Group Limited Warrant signed on 2667 Greenford Rec: 1892/3 dt Wef: 17/03/2005 Vide PT 2667 receptor antagonists Att: SS & Co. 31/10/2005 Middlesex UB6 ONN, 16/03/2005 Great Britain

235 East 42nd Street, Filing Date: 15/03/2005 Wef: 17/03/2004 Compounds useful for the Pfizer Inc. New York , New York Warrant signed on 2668 Rec: 1889/90 dt Wef: 27/07/2004 Vide PT 2668 treatment of diseases Att: SS & Co. 10017, United States of 31/10/2005 16/03/2005 Wef: 12/11/2004 America

Eastern Point Road, Filing Date: 15/03/2005 Novel Benzyl(Idene) - Pfizer Products Inc. Groton, Connecticut Warrant signed on 2669 Rec: 1886/7 dt Wef: 17/03/2004 Vide PT 2669 Lactam derivatives Att: SS & Co. 06340, United States of 31/10/2005 16/03/2005 America Industriparken 55, DK- Filing Date: 15/03/2005 Stereoselective synthesis of Leo Pharma A/S Wef: 18/03/2004 Warrant signed on 2670 2750 Ballerup, Rec: 1883/4 dt Vide PT 2670 vitamin D analogues Att: SS & CO. Wef: 22/03/2004 31/10/2005 Denmark 16/03/2005

Filing Date: 15/03/2005 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 22/03/2004 Warrant signed on 2671 Therapeutic agents Rec: 1880/1 dt Vide PT 2671 Att: SS & Co. Sweden Wef: 12/11/2004 31/10/2005 16/03/2005

Imidazole compounds for Eastern Point Road, Filing Date: 15/03/2005 the treatment of Pfizer Products Inc. Groton, Connecticut Warrant signed on 2672 Rec: 1877/8 dt Wef: 23/03/2004 Vide PT 2672 neurodegenerative Att: SS & Co. 06340, United States of 31/10/2005 16/03/2005 disorders America

Glaxo Wellcome House, Pyrazolo [3,4-b] pyridine Berkeley Avenue, Filing Date: 15/03/2005 Glaxo Group Limited Warrant signed on 2673 compound, and its use as Greenford Rec: 1874/5 dt Wef: 16/03/2004 Vide PT 2673 Att: SS & Co. 31/10/2005 PDE4 inhibitor Middlesex UB6 ONN, 16/03/2005 Great Britain

Dipharma SpA. Filing Date: 15/03/2005 Intermediates for the Via XXV Maggio 40, Wef: 19/03/2004 Warrant signed on 2674 Att: Emmanuel Mallia & Rec: 1758/9 dt Vide PT 2674 preparation of pramipexole Mereto di Tomba, Italy Wef: 28/01/2005 31/10/2005 Associates 15/03/2005

P.O Box 4000, Route 206 and Province Line Prodrugs of piperazine and Bristol-Myers Squibb Filing Date: 15/03/2005 Road, Princeton, New Wef: 15/03/2004 Warrant signed on 2675 substituted piperidine Company Rec: 1777/8 dt Vide PT 2675 Jersey 08543-4000, Wef: 10/12/2004 31/10/2005 antiviral agents Att: MAMO TCV Advocates 15/03/2005 United States of America

P.O Box 4000, Route 206 and Province Line THERAPEUTIC SYNERGY Bristol-Myers Squibb Filing Date: 15/03/2005 Road, Princeton, New Warrant signed on 2676 OF ANTI-CANCER Company Rec: 1780/1 dt Wef: 16/03/2004 Vide PT 2676 Jersey 08543-4000, 31/10/2005 COMPOUNDS Att: MAMO TCV Advocates 15/03/2005 United States of America

Use of a pyrazole derivative for preparing medicinal products that are useful in Filing Date: 16/03/2005 the prevention and Sanofi - Aventis 174 Avenue de France, Warrant signed on 2677 Rec: 1868/9 dt Wef: 17/03/2004 Vide PT 2677 treatment of chronic Att: SS & Co. FR-75013 Paris, France 31/10/2005 16/03/2005 bronchitis and of chronic obstructive pulmonery disease

Zugerstrasse 8, CM- Filing Date: 16/03/2005 Cream - gel containing iver Galderma S.A. Warrant signed on 2678 6330 Cham, Rec: 1865/6 dt Wef: 18/03/2004 Vide PT 2678 rectin Att: SS & Co. 31/10/2005 Switzerland 16/03/2005 235 East 42nd Street, Filing Date: 16/03/2005 Compounds for the Pfizer Inc. New York , New York Wef: 23/03/2004 Warrant signed on 2679 Rec: 1862/3 dt Vide PT 2679 treatment of diseases Att: SS & Co. 10017, United States of Wef: 03/11/2004 31/10/2005 16/03/2005 America

235 East 42nd Street, Wef: 23/03/2004 Filing Date: 21/03/2005 Compounds for the Pfizer Inc. New York , New York Wef: 27/07/2004 Warrant signed on 2680 Rec: 2075/6 dt Vide PT 2680 treatment of diseases Att: SS & Co. 10017, United States of Wef: 21/09/2004 31/10/2005 21/03/2005 America Wef: 05/11/2004

235 East 42nd Street, Filing Date: 21/03/2005 Formamide derivatives for Pfizer Inc. New York , New York Wef: 23/03/2004 Warrant signed on 2681 Rec: 2073/4 dt Vide PT 2681 the treatment of diseases Att: SS & Co. 10017, United States of Wef: 12/1120/04 31/10/2005 21/03/2005 America

Via della Clinica, 9 Filing Date: 21/03/2005 Process for the preparation Zambon Group SpA Warrant signed on 2682 36100 - Vicenza, Rec: 2070/1 dt Wef: 25/03/2004 Vide PT 2682 of gabapentin Att: SS & CO 31/10/2005 Italy 21/03/2005

Alpha aryl or heteroaryl 235 East 42nd Street, methyl Beta piperidino Filing Date: 21/03/2005 Pfizer Inc. New York , New York Warrant signed on 2683 propanoic acid compounds Rec: 2066/7 dt Wef: 29/03/2004 Vide PT 2683 Att: SS & Co. 10017, United States of 31/10/2005 as 6rl 1-receptor 21/03/2005 America antagonists

Controlled-release 4 - 6-10 Koishikawa, Filing Date: 22/03/2005 pharmaceutical composition Eisai Co. Ltd Warrant signed on 2684 Bunkyo-ku Tokyo, Rec: 2111/2 dt Wef: 26/03/2004 Vide PT 2684 and method for producing Att: GS Services Limited 31/10/2005 Japan 22/03/2005 same.

1120 Veterans Boulevard, South San Pyrazole compounds and Amgen SF LLC Filing Date: 23/03/2005 Warrant signed on 2685 Francisco, California Wef: 23/03/2004 Vide PT 2685 uses related thereto. Att: SDr M. Chetcuti Cauchi Rec: 664 dt 03/01/2007 31/10/2005 94080, United States of America

One Franklin Plaza, Wef: 26/03/2004 P.O. Box 7929, Filing Date: 23/03/2005 Glaxo Group Limited Wef: 26/03/2004 Warrant signed on 2686 Compounds Philadelphia, PA 19101, Rec: 2299/300 dt Vide PT 2686 Att: SS & Co. Wef: 15/10/2004 31/10/2005 United States of 28/03/2005 Wef: 15/10/2004 America

One Amgen Center Filing Date: 23/03/2005 Chemically modified protein Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2687 Rec: 2296/7 dt Wef: 23/03/2004 Vide PT 2687 compositions and methods Att: SS & Co. California 91320-1799, 31/10/2005 28/03/2005 USA P.O Box 4000, Bristol-Myers Squibb Filing Date: 23/03/2005 Methods of treating HIV Princeton, New Jersey Warrant signed on 2688 Company Rec: 2280/1 dt Wef: 24/03/2004 Vide PT 2688 infection 08543-4000, United 31/10/2005 Att: MAMO TCV Advocates 28/03/2005 States of America

P.O Box 4000, Bristol-Myers Squibb Filing Date: 23/03/2005 Methods of treating HIV Princeton, New Jersey Warrant signed on 2689 Company Rec: 2277/8 dt Wef: 24/03/2004 Vide PT 2689 infections 08543-4000, United 31/10/2005 Att: MAMO TCV Advocates 28/03/2005 States of America

P.O Box 4000, Bristol-Myers Squibb Filing Date: 23/03/2005 Methods of treating HIV Princeton, New Jersey Warrant signed on 2690 Company Rec: 2274/5 dt Wef: 24/03/2004 Vide PT 2690 infections 08543-4000, United 31/10/2005 Att: MAMO TCV Advocates 28/03/2005 States of America

P.O Box 4000, Bristol-Myers Squibb Filing Date: 23/03/2005 Coated tablet formulation Princeton, New Jersey Wef: 25/03/2004 Warrant signed on 2691 Company Rec: 2271/2 dt Vide PT 2691 and method 08543-4000, United Wef: 01/02/2005 31/10/2005 Att: MAMO TCV Advocates 28/03/2005 States of America

Infusion preparation 1-5 Dishomacini 2 Filing Date: 29/03/2005 comprising (2R) - 2 - Ono Pharmaceutical Co Ltd. Chonie Chiuw-Ku, Warrant signed on 2693 Rec: 2357/8 dt Wef: N/A Vide PT 2693 propyloctanoic acid as an Att: Dr. M. Chetcuti Cauchi Osaka - Shi Osaka 541- 04/10/2006 29/03/2005 active ingredient 8526, Japan

P.O Box 4000, Synergistic methods and Bristol-Myers Squibb Filing Date: 29/03/2005 Princeton, New Jersey Warrant signed on 2694 compositions for treating Company Rec: 2397/8 dt Wef: 31/03/2004 Vide PT 2694 08543-4000, United 3/11/2005 cancer Att: MAMO TCV Advocates 29/03/2005 States of America

P.O Box 4000, Bristol-Myers Squibb Filing Date: 29/03/2005 Novel therapeutic agents for Princeton, New Jersey Warrant signed on 2695 Company Rec: 2394/5 dt Wef: 29/03/2004 Vide PT 2695 the treatment of migraine 08543-4000, United 31/10/2005 Att: MAMO TCV Advocates 29/03/2005 States of America

One Franklin Plaza, PO Smithkline Beecham Filing Date: 29/03/2005 Spray dried pharmaceutical Box 7929, Philadelphia, Warrant signed on 2696 Corporation Rec: 2391/2 dt Wef: 30/0320/04 Vide PT 2696 composition Pennsylvania 10101, 31/10/2005 Att: SS & Co. 29/03/2005 USA Eastern Point Road, Radiographic quantitation Filing Date: 29/03/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2697 method for assessing Rec: 2388/9 dt Wef: 21/05/2004 Vide PT 2697 Att: SS & CO. 06340, United States of 05/12/2005 periodontal bone loss 29/03/2005 America

Sulfonamide compounds for Eastern Point Road, Filing Date: 29/03/2005 the treatment of Pfizer Products Inc. Groton, Connecticut Warrant signed on 2698 Rec: 2385/6 dt Wef: 01/04/2004 Vide PT 2698 neurodegenerative Att: SS & CO. 06340, United States of 03/11/2006 29/03/2005 disorders America

Filing Date: 29/03/2005 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 03/04/2004 Warrant signed on 2699 Therapeutic agents Rec: 2382/3 dt Vide PT 2699 Att: SS & Co. Sweden Wef: 18/09/2004 03/11/2005 29/03/2005

Novel method for the Industriparken 55, DK- Filing Date: 29/03/2005 preparation of intermediates Leo Pharma A/S Warrant signed on 2700 2750 Ballerup, Rec: 2379/80 dt Wef: 02/04/2004 Vide PT 2700 useful for the synthesis of Att: SS & CO. 3/11/2005 Denmark 29/03/2005 vitamin D analogues

Eastern Point Road, Microfluidized oil-in-water Filing Date: 29/03/2005 Pfizer Inc. Groton, Connecticut Warrant signed on 2701 emulsions and vaccine Rec: 2377/8 dt Wef: 05/04/2004 Vide PT 2701 Att: SS & Co. 06340,United States of 3/11/2005 compositions 29/03/2005 America

Glaxo Wellcome House, Filing Date: 29/03/2005 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2702 Immunoglobulins Rec: 2374/5 dt Wef: 30/03/2004 Vide PT 2702 Attn: S S & Co Greenford, Middlesex, 3/11/2005 29/03/2005 UB6 ONN, Great Britain

40 Landsdowne Street, Filing Date: 30/03/2005 Synthesis of boronic ester Millenium Pharmaceuticals Cambridge Warrant signed on 2703 Rec: 2481/2 dt Wef: 30/03/2004 Vide PT 2703 and acid compounds Inc Att: Bezzina & Mifsud Massachusetts 02139, 03/11/2005 01/04/2005 USA

Pharmaceutical 1-5 Doshomachi, 2 Filing Date: 30/03/2005 composition comprising Ono Pharmaceutical Co Ltd. Chome, Chuo-Ku, Warrant signed on 2704 Rec: P585381 dt Wef: N/A Vide PT 2704 (2R) - 2 - propyloctonoic Att: Dr. M. Chetcuti Cauchi Osaka - Shi, Osaka 04/10/2006 30/03/2005 acid as an active ingredient 541-8526, Japan

901 Gateway Quinolinone - carboxamide Filing Date: 01/04/2005 Theravance Inc Boulevard, South San Warrant signed on 2705 compounds as 5-HT4 Rec: 2516/7 dt Wef: 07/04/2004 Vide PT 2705 Att: SS & CO. Francisco , CA 94080, 03/11/2005 receptor agonists 01/04/2005 USA

58, South Service, 6, 6-Bicyclic ring Filing Date: 01/04/2005 OSI Pharmaceuticals Inc Dadd Suite 110, Warrant signed on 2706 substituted heterobicylic Rec: 2522/3 dt Wef: 02/04/2004 Vide PT 2706 Att: SS & CO. Melville, NY 11747, 03/11/2005 protein kinase inhibitors 01/04/2005 USA Glaxo Wellcome House, Filing Date: 01/04/2005 Wef: 02/04/2004 Chemical process and new Glaxo Group Limited Berkeley Avenue, Warrant signed on 2707 Rec: 2519/20 dt Wef: 25/05/2004 Vide PT 2707 crystalline form Attn: S S & Co Greenford, Middlesex, 03/11/2005 01/04/2005 Wef: 26/05/2004 UB6 ONN, Great Britain

Filing Date: 01/04/2005 D-Homo-17-Chlor-16(17)-En Schering AG Warrant signed on 2708 Berlin 13342, Germany Rec: 2525/6 dt Wef: 08/04/2004 Vide PT 2708 Steroide Att: MAMO TCV Advocates 03/11/2005 01/04/2005

One Amgen Center Filing Date: 04/04/2005 Methods of reducing Amgen Inc. Drive, Thousand Oaks, Wef: 02/04/2004 Warrant signed on 2709 Rec: 2593/4 dt Vide PT 2709 aggregation of 1L-IRA Att: B&M Patentbureau California 91320-1799, Wef: 12/08/2004 03/11/2005 04/04/2005 USA

Substituted 4-alkyl - and 4 - Filing Date: 05/04/2005 alkanoyl - piperidine Janssen Pharmaceutica NV Tumhoutseweg 30, B- Warrant signed on 2710 Rec: 2622/3 dt Wef: 08/04/2004 Vide PT 2710 derivatives and their use as Att: EMD Advocates 2340 Beerse, Belgium 03/11/2005 05/04/2005 neurokinin antagonists

Substituted Diaza-Spiro Filing Date: 05/04/2005 [4,5] - Decane derivatives Janssen Pharmaceutica NV Tumhoutseweg 30, B- Warrant signed on 2711 Rec: 2619/20 dt Wef: 06/04/2004 Vide PT 2711 and their use as neurokonin Att: EMD Advocates 2340 Beerse, Belgium 03/11/2005 05/04/2005 antagonists

Substituted diaza-spiro [5- Filing Date: 05/04/2005 5,] - lindecane derivatives Janssen Pharmaceutica NV Tumhoutseweg 30, B- Warrant signed on 2712 Rec: 2616/7 dt Wef: 06/04/2004 Vide PT 2712 and their use as nerokinin Att: EMD Advocates 2340 Beerse, Belgium 03/11/2005 05/04/2005 antagonists

PO Box 4000, Route Bicyclic heterocycles useful Bristol-Myers Squibb 206 & Province Line Filing Date: 11/04/2005 Wef: 13/04/2004 Warrant signed on 2713 as serine protease Company Road, Princeton, New Rec: 2796/7 dt Vide PT 2713 Wef: 12/11/2004 03/11/2005 inhibitors Att: MAMO TCV Advocates Jersey 08543 - 4000, 11/04/2005 U.S.A.

Eastern Point Road, Filing Date: 12/04/2005 Dipeptidyl peptidase - IV Pfizer Products Inc. Groton, Connecticut Wef: 14/04/2004 Warrant signed on 2714 Rec: 2844/5 dt Vide PT 2714 Inhibitors Att: SS & Co. 06340, United States of Wef: 07/03/2005 3/11/2005 12/04/2005 America

Stereoselective Eastern Point Road, Filing Date: 12/04/2005 bioconversion of alphatic Pfizer Products Inc. Groton, Connecticut Warrant signed on 2715 Rec: 2847/8 dt Wef: 14/04/2004 Vide PT 2715 dinitriles into cyano Att: SS & Co. 06340, United States of 03/11/2005 12/04/2005 carboxylic acids America

Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 12/04/2005 Wef: 16/04/2004 Warrant signed on 2716 Novel Imidazoles LLC Plains, New Jersey Rec: 2850/1 dt Wef: 10/08/2004 Vide PT 2716 03/11/2005 Att: SS & Co. 07950, USA 12/04/2005 Wef: 11/08/2004 1- Aminophthalazine Filing Date: 12/04/2005 derivatives, preparation Sanofi - Aventis 174 Avenue de France, Warrant signed on 2717 Rec: 2842/3 dt Wef: 13/04/2004 Vide PT 2717 thereof and therapeutic Att: SS & Co. FR-75013 Paris, France 21/12/2005 12/04/2005 applications thereof.

One Amgen Center Filing Date: 14/04/2005 Aryl sulfones and uses Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2718 Rec: 2998/9 dt Wef: 14/04/2004 Vide PT 2718 related Att: S S & Co. California 91320-1799, 03/11/2005 18/04/2005 USA

Eisai R&D Management Co. 6-10 Koishikawa, 4- Filing Date: 15/04/2005 Warrant signed on 2719 Imidazopyridine compound Ltd Att: SS chome, Bunkyo-ku, Rec: 2995/6 dt Wef: 22/04/2004 Vide PT 2719 03/11/2005 & CO Tokyo, Japan 18/04/2005

Multiphase product for Filing Date: 15/04/2005 Schering AG Warrant signed on 2720 contraception based on a Berlin 13342, Germany Rec: 2993/4 dt Wef: 20/04/2004 Vide PT 2720 Att: MAMO TCV Advocates 03/11/2005 natural oestrogen 18/04/2005

Filing Date: 15/04/2005 Schering AG Warrant signed on 2721 17 alpha - Floursteroide Berlin 13342, Germany Rec: 2991/2 dt Wef: 19/04/2004 Vide PT 2721 Att: MAMO TCV Advocates 03/11/2005 18/04/2005

PO Box 4000, Route Bristol-Myers Squibb 206 & Province Line Filing Date: 15/04/2005 Fused heterocyclic Warrant signed on 2722 Company Road, Princeton, New Rec: 2988/9 dt Wef: 15/04/2004 Vide PT 2722 compounds 03/11/2005 Att: MAMO TCV Advocates Jersey 08543 - 4000, 18/04/2005 U.S.A.

New compounds with Filing Date: 19/04/2005 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2723 favourable biological Rec: 3039/40 dt Wef: 19/04/2004 Vide PT 2723 Att: SS & Co. FR-75013 Paris, France 03/11/2005 activity 19/04/2005

Filing Date: 19/04/2005 Astrazeneca AB SE - 151 85 Sodertalje, Wef: 23/04/2004 Warrant signed on 2724 Chemical compounds Rec: 3036/7 dt Vide PT 2724 Att: SS & Co. Sweden Wef: 10/01/2005 03/11/2005 19/04/2005

Pharmacia & Upjohn 301 Henrietta Street, Filing Date: 19/04/2005 Cellular permissivity factor Wef: 23/04/2004 Warrant signed on 2725 Company Kalamazoo, Michigan Rec: 3033/4 dt Vide PT 2725 for viruses and uses thereof Wef: 09/12/2004 03/11/2005 Att: SS & Co. 49001, USA 19/04/2005

6 - Substituted Filing Date: 20/04/2005 pyridoindoline derivatives Sanofi - Aventis 174 Avenue de France, Warrant signed on 2726 Rec: 3131/2 dt Wef: 21/04/2004 Vide PT 2726 their preparation and their Att: SS & Co. FR-75013 Paris, France 03/11/2005 25/04/2005 application in therapeutics

One Amgen Center Filing Date: 20/04/2005 Arylsulfonamides and uses Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2727 Rec: 3134/5 dt Wef: 20/04/2004 Vide PT 2727 related thereto. Att: SS & Co. California 91320-1799, 03/11/2005 25/04/2005 USA One Procter & Gamble Filing Date: 21/04/2005 Tri-substituted ureas as The Procter & Gamble Plaza Cincuinati, OH Warrant signed on 2728 Rec: 3140/1 dt Wef: 22/04/2004 Vide PT 2728 cytokine inhibitors Att: SS & Co. 45202, United States of 03/11/2005 25/04/2005 America

One Procter & Gamble Filing Date: 21/04/2005 Tri-substituted ureas as The Procter & Gamble Plaza Cincuinati, OH Warrant signed on 2729 Rec: 3143/4 dt Wef: 22/04/2004 Vide PT 2729 cytokine inhibitors Att: SS & Co. 45202, United States of 03/11/2005 25/04/2005 America

One Amgen Center Antibodies to angiogenesis Filing Date: 22/04/2005 Amgen Inc. Drive, Thousand Oaks, Wef: 23/04/2004 Warrant signed on 2730 inhibiting domains of CD Rec: 3156/7 dt Vide PT 2730 Att. MAMO TCV Advocates California 91320-1799, Wef: 06/07/2004 03/11/2005 148 25/04/2005 USA

One Amgen Center Filing Date: 22/04/2005 Wef: 23/04/2004 Anti-CD148 antibodies and Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2731 Rec: 3153/4 dt Wef: 14/05/2004 Vide PT 2731 binding epitopes there for Att. MAMO TCV Advocates California 91320-1799, 03/11/2005 25/04/2005 Wef: 06/07/2004 USA

PO Box 4000, Route Bristol-Myers Squibb 206 & Province Line Filing Date: 22/04/2005 Bicyclic heterocycles as Warrant signed on 2732 Company Road, Princeton, New Rec: 3150/1 dt Wef: 26/04/2004 Vide PT 2732 kinase inhibitors 03/11/2005 Att: MAMO TCV Advocates Jersey 08543 - 4000, 25/04/2005 U.S.A.

PO Box 4000, Route Bristol-Myers Squibb 206 & Province Line Filing Date: 22/04/2005 Monocyclic heterocycles as Wef: 23/04/2004 Warrant signed on 2733 Company Road, Princeton, New Rec:3147/8 dt Vide PT 2733 kinase inhibitors Wef: 23/12/2004 03/11/2005 Att: MAMO TCV Advocates Jersey 08543 - 4000, 25/04/2005 U.S.A.

One Amgen Center Filing Date: 25/04/2005 Sustained-release Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2734 Rec: 3161/2 dt Wef:23/04/2004 Vide PT 2734 formulations Att: SS & Co. California 91320-1799, 03/11/2005 25/04/2005 USA

Glaxo House, Berkeley Filing Date: 26/04/2005 Muscarinic acetylcholine Glaxo Group Limited Avenue, Greenford, Warrant signed on 2735 Rec: 3213/4 dt Wef: 27/04/2004 Vide PT 2735 receptor antagonists Att: SS & Co. Middlesex, UB6 ONN, 03/11/2005 26/04/2005 Great Britain

235 East 42nd Street, Filing Date: 26/04/2005 Pfizer Inc. New York, New York Warrant signed on 2736 Novel compounds Rec: 3216/7 dt Wef: 30/04/2004 Vide PT 2736 Att: SS & Co. 10017, United States of 03/11/2005 26/04/2005 America Substituted morpholine Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 26/04/2005 compounds for the Warrant signed on 2737 LLC Plains, New Jersey Rec: 3219/20 dt Wef: 30/04/2004 Vide PT 2737 treatment of central nervous 03/11/2005 Att: SS & Co. 07950, USA 26/04/2005 system disorders

235 East 42nd Street, Substituted methyl aryl or Filing Date: 26/04/2005 Pfizer Inc. New York, New York Warrant signed on 2738 heteroaryl amide Rec: 3222/3 dt Wef: 04/05/2004 Vide PT 2738 Att: SS & Co. 10017, United States of 21/11/2005 compounds 26/04/2005 America

235 East 42nd Street, Ortho substituted aryl or Filing Date: 26/04/2005 Pfizer Inc. New York, New York Warrant signed on 2739 heteroaryl amide Rec: 3225/6 dt Wef: 04/05/2004 Vide PT 2739 Att: SS & Co. 10017, United States of 21/11/2005 compounds 26/04/2005 America

Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 26/04/2005 4-phenylamino-quinazolin-6- Warrant signed on 2740 LLC Plains, New Jersey Rec: 3228/9 dt Wef: 06/05/2004 Vide PT 2740 Yl-amides 21/11/2005 Att: SS & Co. 07950, USA 26/04/2005

Crystalline forms of Teva Pharmaceutical 5, Basel Street, PO Box Filing Date: 26/04/2005 Wef: 26/04/2004 fexofenadine hydrochloride Warrant signed on 2743 Industries Ltd 3190, Petah Tiqva Rec: 3244/5 dt Wef: 21/06/2004 Vide PT 2743 and processes for their 3/11/2005 Att: Dr. M. Chetcuti Cauchi 49131, Israel 26/04/2005 Wef: 25/06/2004 preparation

PO Box 4000, Route Composition for enhancing Bristol-Myers Squibb 206 & Province Line Filing Date: 28/04/2005 Warrant signed on 2744 absorption of a drug and Company Road, Princeton, New Rec: 3299/3300 dt Wef: 28/04/2004 Vide PT 2744 03/11/2005 method Att: MAMO TCV Advocates Jersey 08543 - 4000, 29/4/2005 U.S.A.

Wef: 30/04/2004 Management of Filing Date: 28/04/2005 Wef: 28/05/2004 breakthrough bleeding in Schering AG Warrant signed on 2745 Berlin 13342, Germany Rec: 3302/3 dt Wef: 07/06/2004 Vide PT 2745 extended hormonal Att: MAMO TCV Advocates 3/11/2005 29/04/2005 Wef: 27/12/2004 contraceptive regimens Wef: 10/03/2005

Wedswood Way, Resolution Chemicals Filing Date: 29/04/2005 Stevenage, Warrant signed on 2746 Preparation of cabergoline Limited Rec: 3311/2 dt Wef: 30/04/2004 Vide PT 2746 Hertfordshire SG1 4QT, 3/11/2005 Att: SS & Co 29/04/2005 United Kingdom

3-or 4-monosubstituted Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 03/05/2005 phenol and thiophenol Wef: 07/05/2004 Warrant signed on 2748 LLC Plains, New Jersey Rec: 3404/5 dt Vide PT 2748 derivatives useful as Hs Wef: 04/03/2004 21/11/2005 Att: SS & Co. 07950, USA 03/05/2005 ligands Novel Biaromatic compunds which activate PRARY-Type Galderma Research & 635 route des Lucides, Filing Date: 03/05/2005 receptors, their process of Warrant signed on 2749 Development, S.N.C. BP 87 06902 Sophia Rec: 3407/8 dt Wef: 06/05/2004 Vide PT 2749 preparation and their 21/11/2005 Att: SS & CO. Antipolis Cedex, France 03/05/2005 cosmetic or pharmaceutical compositions

Pyrrolidinyl derivatives as II- Filing Date: 04/05/2005 Janssen Pharmaceutica NV Turnhouteweg 30, B- Warrant signed on 2751 Beta hydroxysteroid Rec: 3444/5 dt Wef: 07/05/2004 Vide PT 2751 Att: EMD Advocates 2340 Beerse, Belgium 21/11/2005 dehydrogenase inhibitors 04/05/2005

Admantyl pyrrolidin - 2- One Filing Date: 04/05/2005 derivatives as II - Beta Janssen Pharmaceutica NV Turnhouteweg 30, B- Warrant signed on 2752 Rec: 3446/7 dt Wef: 07/05/2004 Vide PT 2752 hydroxysteroid Att: EMD Advocates 2340 Beerse, Belgium 21/11/2005 04/05/2005 dehydrogenase inhibitors

Trimetric, macrocyclically Filing Date: 05/05/2005 Schering AG Warrant signed on 2755 substituted halo-benzene Berlin 13342, Germany Rec: 3483/4 dt Wef: 05/05/2004 Vide PT 2755 Att: MAMO TCV Advocates 21/11/2005 derivatives 09/05/2005

280 East Grand Avenue, South San Francisco, CA 94080, Cytokinetics Inc. & United States of Filing Date: 06/05/2005 Certain chemical entities, Smithkline Beecham Warrant signed on 2756 America & One Rec: 3486/7 dt Wef: 06/05/2004 Vide PT 2756 compositions and methods Corporation 21/11/2005 Franklin Plaza, 09/05/2005 Att: SS & Co. Philadelphia, PA 19101, United States of America

One Amgen Center Protein kinase modulators Amgen Inc. Drive, Thousand Oaks, Filing Date: 09/05/2005 Warrant signed on 2757 Wef: 07/05/2004 Vide PT 2757 and method of use Att: Dr M Chetcuti Cauchi California 91320-1799, P585394 dt 09/05/2005 21/11/2005 USA

Eastern Point Road, Filing Date: 10/05/2005 Pfizer Products Inc. Groton, Connecticut Wef: 12/05/2004 Warrant signed on 2758 Therapeutic compounds Rec: 3590/1 dt Vide PT 2758 Att: SS & CO. 06340, United States of Wef: 21/03/2005 21/11/2005 10/05/2005 America

Eastern Point Road, Pyrimidine derivatives for Filing Date: 10/05/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2759 the treatment of abnormal Rec: 3587/8 dt Wef: 14/05/2004 Vide PT 2759 Att: SS & CO. 06340, United States of 21/11/2005 cell growth 10/05/2005 America

Eisai R&D Management Co. 6-10 Koishikawa, 4- Filing Date: 10/05/2005 Indole derivative having Warrant signed on 2760 Ltd Att: SS chome, Bunkyo-ku, Rec: 3584/5 dt Wef: 12/04/2004 Vide PT 2760 piperidine ring 21/11/2005 & Co. Tokyo, Japan 10/05/2005 2H - OR 3H-Benzo [e] Indazol - 1 - YL carbamate Filing Date: 10/05/2005 Sanofi - Aventis 174 Avenue de France, Warrant signed on 2761 derivatives, their Rec: 3581/2 dt Wef: 11/05/2004 Vide PT 2761 Att: SS & Co. FR-75013 Paris, France 21/11/2005 preparation and their 10/05/2005 application in therapeutics

235 East 42nd Street, Filing Date: 10/05/2005 Tetrahydronaphthyridine Pfizer Inc. New York, New York Warrant signed on 2762 Rec: 3578/9 dt Wef: 12/05/2004 Vide PT 2762 derivatives Att: SS & Co. 10017, United States of 21/11/2005 10/05/2005 America

Medichem S.A. Fructuos Gelabert, 68, Filing Date: 11/05/2005 Process for the preparation Warrant signed on 2764 Att: GS Services Ltd - Dr A. E-08970, Sant Joan Rec: 3609/10 dt Wef: 12/05/2004 Vide PT 2764 of rosiglitazone 21/11/2005 Sammut Despi, Spain 11/05/2005

PO Box 4000, Route HIV Integrase inhibitors Bristol-Myers Squibb 206 & Province Line Filing Date: 11/05/2005 Warrant signed on 2766 cyclic pyrimidinone Company Road, Princeton, New Rec: 3639/40 dt Wef: 12/05/2004 Vide PT 2766 21/11/2005 compounds Att: MAMO TCV Advocates Jersey 08543 - 4000, 11/05/2005 USA

PO Box 4000, Route Urea antagonists of P2Y1 Bristol-Myers Squibb 206 & Province Line Filing Date: 11/05/2005 receptor useful in the Wef: 12/05/2004 Warrant signed on 2767 Company Road, Princeton, New Rec: 3636/7 dt Vide PT 2767 treatment of thrombotic Wef: 28/08/2005 21/11/2005 Att: MAMO TCV Advocates Jersey 08543 - 4000, 11/05/2005 conditions USA

PO Box 4000, Route Urea antagonists of P2Y1 Bristol-Myers Squibb 206 & Province Line Filing Date: 11/05/2005 receptor useful in the Wef: 12/05/2004 Warrant signed on 2768 Company Road, Princeton, New Rec: 3633/4 dt Vide PT 2768 treatment of thrombotic Wef: 28/03/2005 21/11/2005 Att: MAMO TCV Advocates Jersey 08543 - 4000, 11/05/2005 compounds USA

159, C.S.T. Road, Filing Date: 12/05/2005 An antimyicobacterial Lupin Ltd Kaluria Santacruz Warrant signed on 2769 Rec: 3642/3 dt Wef: 12/05/2004 Vide PT 2769 pharmaceutical composition Att: Dr. M. Chetcuti Cauchi (East), Mumbai 400098, 21/11/2005 12/05/2005 Maharashtra

New pyrrolidine and thiazolidine compounds, a process for their 12, Place de la Defense Filing Date: 17/05/2005 Les Laboratoire Servier Warrant signed on 2770 preparation and 92415 Courbevoie Rec: 3769/70 dt Wef: 19/05/2004 Vide PT 2770 Att: SS & Co. 21/11/2005 pharmaceutical Cedex, France 17/05/2005 compositions containing them

Filing Date: 17/05/2005 Pharmaceutical Astrazeneca AB S - 151 85 Sodertalje, Warrant signed on 2771 Rec: 3772/3 dt Wef: 21/05/2004 Vide PT 2771 compositions Att: SS & Co. Sweden 05/12/2005 17/05/2005 Eastern Point Road, Tetraazabenza [e] aziulene Filing Date: 17/05/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2772 derivates and analogs there Rec: 3774/5 dt Wef: 25/05/2004 Vide PT 2772 Att: SS & Co. 06340, United States of 05/12/2005 of 17/05/2005 America

Filing Date: 17/05/2005 Astrazeneca AB S - 151 85 Sodertalje, Wef: 25/05/2004 Warrant signed on 2773 Chemical compounds Rec: 3777/8 dt Vide PT 2773 Att: SS & Co. Sweden Wef: 05/01/2005 05/12/2005 17/05/2005

235 East 42nd Street, New Indazole and indolone Filing Date: 17/05/2005 Pfizer Inc. New York , New York Wef: 26/05/2004 Warrant signed on 2774 derivatives and their use as Rec: 3780/1 dt Vide PT No 2774 Att: SS & Co. 10017, United States of Wef: 09/07/2004 05/12/2005 pharmaceuticals 17/05/2005 America.

Filing Date: 17/05/2005 Therapeutic compounds: Astrazeneca AB S - 151 85 Sodertalje, Warrant signed on 2775 Rec: 3783/4 dt Wef: 25/05/2004 Vide PT 2775 pryridine as scaffold Att: SS & Co. Sweden 21/12/2005 17/05/2005

Eastern Point Road, Filing Date: 17/05/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2776 New use Rec: 3766/7 dt Wef: 25/05/2004 Vide PT 2776 Att: SS & Co. 06340, United States of 05/12/2005 17/05/2005 America

Filing Date: 17/05/2005 Astrazeneca AB S - 151 85 Sodertalje, Warrant signed on 2777 Therapeutic compounds Rec: 3763/4 dt Wef: 25/05/2004 Vide PT 2777 Att: SS & Co. Sweden 05/12/2005 17/05/2005

P.O Box 4000, Route 206 and Province Line Bristol-Myers Squibb Road, Princeton, New Nanoparticle dispersion Filing Date: 18/05/2005 Company & Elan Pharma Jersey 08543-4000, Warrant signed on 2778 containing lactam Rec: 3804/5 dt Wef: 18/05/2004 Vide PT 2778 International Limited U.S.A. & Treasury 05/12/2005 compound 18/05/2005 Att: MAMO TCV Advocates Building, Lower Grand Canal Street, Dublin 2, Ireland

Chromanol derivatives, a Filing Date: 18/05/2005 process for their production Schering AG Warrant signed on 2779 Berlin 13342, Germany Rec: 3807/8 dt Wef: 19/05/2004 Vide PT 2779 and their use as anti- Att: MAMO TCV Advocates 05/12/2005 18/05/2005 inflammatory agents

Filing Date: 18/05/2005 Estriol and Estetrol Schering AG Warrant signed on 2780 Berlin 13342, Germany Rec: 3809/10 dt Wef: 21/05/2004 Vide PT 2780 prodrugs Att: MAMO TCV Advocates 05/12/2005 18/05/2005 Filing Date: 18/05/2005 Steroid prodrugs with Schering AG Warrant signed on 2781 Berlin 13342, Germany Rec: 3812/3 dt Wef: 21/05/2004 Vide PT 2781 androgenic action Att: MAMO TCV Advocates 05/12/2005 18/05/2005

Filing Date: 18/05/2005 Schering AG Warrant signed on 2782 Estradoil prodrugs Berlin 13342, Germany Rec: 3815/6 dt Wef: 21/05/2004 Vide PT 2782 Att: MAMO TCV Advocates 05/12/2005 18/05/2005

289, Bellasis Road, Filing Date: 19/05/2005 Chipla Limited Mumbai Central, Warrant signed on 2784 Medicament inhaler device Rec: 3839/40 dt Wef: 19/05/2004 Vide PT 2784 Att: SS & Co. Mumbai 400008, 21/12/2005 19/05/2005 Maharashtra, India

2-1, Toranomon, 2- Filing Date: 20/05/2005 Stable crystal of 4- Japan Tobacco Inc. chome, Minato-ku, Warrant signed on 2785 Rec: 3884/5 dt Wef: 20/05/2004 Vide PT 2785 oxoquinoline Att: SS & Co. Tokyo, 105-8422, 05/12/2005 23/05/2005 Japan

Wef: 20/05/2004 Wef: 07/06/2004 Wef: 25/01/2005 Teva Pharmaceutical Fine Strada Statale Briantea, Filing Date: 20/05/2005 Preparation of levalbuterol Wef: 07/06/2004 Warrant signed on 2787 Chemicals Srl KM 36, No 83, 23892 Rec: 3911/2 dt Vide PT 2787 hydrochloride Wef: 28/06/2004 05/12/2005 Att: Dr. M. Chetcuti Cauchi Burciago (LC), Italy 23/05/2005 Wef: 28/06/2004 Wef: 13/07/2004 Wef: 21/02/2004

Wef: 20/05/2004 Wef: 07/06/2004 Wef: 25/01/2005 Teva Pharmaceutical Fine Strada Statale Briantea, Filing Date: 20/05/2005 Levalbuterol hydrochloride Wef: 07/06/2004 Warrant signed on 2788 Chemicals Srl KM 36, No 83, 23892 Rec: 3908/9 dt Vide PT 2788 polymorph A Wef: 28/06/2004 05/12/2005 Att: Dr. M. Chetcuti Cauchi Burciago (LC), Italy 23/05/2005 Wef: 28/06/2004 Wef: 13/07/2004 Wef: 21/02/2004

Wef: 20/05/2004 Wef: 07/06/2004 Wef: 25/01/2005 Teva Pharmaceutical Fine Strada Statale Briantea, Filing Date: 20/05/2005 Levalbuterol hydrochloride Wef: 07/06/2004 Warrant signed on 2789 Chemicals Srl KM 36, No 83, 23892 Rec: 3905/6 dt Vide PT 2789 polymorph B Wef: 28/06/2004 05/12/2005 Att: Dr. M. Chetcuti Cauchi Burciago (LC), Italy 23/05/2005 Wef: 28/06/2004 Wef: 13/07/2004 Wef: 21/02/2004

235 East 42nd Street, New aminopyridine Filing Date: 24/05/2005 Pfizer Inc. New York, New York Wef: 27/05/2004 Warrant signed on 2790 derivatives and their use as Rec: 4006/7 dt Vide PT 2790 Att: SS & Co. 10017, United States of Wef: 03/06/2004 05/12/2005 pharmaceuticals 26/05/2005 America Glaxo Wellcome House, Filing Date: 24/05/2005 Glaxo Group Limited Berkeley Avenue, Wef: 24/05/2004 Warrant signed on 2791 Compounds Rec: 4004/5 dt Vide PT 2791 Att: SS & Co. Greenford, Middlesex, Wef: 10/05/2005 05/12/2005 26/05/2005 UB6 ONN, Great Britain

235 East 42nd Street, Melanin concentrating Filing Date: 24/05/2005 Pfizer Inc. New York, New York Wef: 27/05/2004 2792 hormone receptor Rec: 4001/2 dt WITHDRAWN Vide PT 2792 Att: SS & Co. 10017, United States of Wef: 23/03/2005 antagonists 26/05/2005 America

Eisai R&D Management Co. 6-10 Koishikawa, 4- Filing Date: 24/05/2005 Wef: 26/05/2004 Warrant signed on 2793 Cinnamide compound Ltd Att: SS chome, Bunkyo-ku, Rec: 3998/9 dt Vide PT 2793 Wef: 26/10/2004 05/12/2005 & Co. Tokyo, Japan 26/05/2005

One Amgen Center Inhibitors of II-Beta-Hydroxy Drive, Thousand Oaks, Filing Date: 24/05/2005 Wef: 24/05/2004 Amgen Inc. & Biovitum AB Warrant signed on 2794 steroid dehydrogenase type California, USA & SK- Rec: 3995/6 dt Wef: 15/10/2004 Vide PT 2794 Attn: S S & Co. 05/12/2005 I 122 76, Stockholm, 26/05/2005 Wef: 31/01/2005 Sweden

Use of substituted quinoline Filing Date: 24/05/2005 derivatives for the treatment Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2795 Rec: 3954/5 dt Wef: 28/05/2004 Vide PT 2795 of drug resistant Att: EMD Advocates 2340 Beerse, Belgium 05/12/2005 24/05/2005 mycobacterial diseases

Filing Date: 24/05/2005 Mercaptoimidazoles as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2796 Rec: 3951/2 dt Wef: 26/05/2004 Vide PT 2796 CCR2 receptor antogonists Att: EMD Advocates 2340 Beerse, Belgium 05/12/2005 24/05/2005

Filing Date: 24/05/2005 Mercaptoimidazoles as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2797 Rec: 3948/9 dt Wef: 26/05/2004 Vide PT 2797 CCR2 receptor antogonists Att: EMD Advocates 2340 Beerse, Belgium 05/12/2005 24/05/2005

P.O Box 4000, Route 206 and Province Line Bristol-Myers Squibb Filing Date: 25/05/2005 Wef: 28/05/2004 Bicyclic heterocycles as HIV Road, Princeton, New Warrant signed on 2798 Company Rec: 3989/90 dt Wef: 20/08/2004 Vide PT 2798 integrase inhibitors Jersey 08543-4000, 05/12/2005 Att: MAMO TCV Advocates 26/05/2005 Wef: 11/05/2005 United States of America

P.O Box 4000, Route 206 and Province Line Bristol-Myers Squibb Filing Date: 25/05/2005 Coated tablet formulation Road, Princeton, New Warrant signed on 2799 Company Rec: 3986/7 dt Wef: 28/05/2004 Vide PT 2799 and method Jersey 08543-4000, 05/12/2005 Att: MAMO TCV Advocates 26/05/2005 United States of America Trimeric, macrocyclically Filing Date: 25/05/2005 substituted Schering AG Warrant signed on 2800 Berlin 13342, Germany Rec: 3982/3 dt Wef: 25/05/2004 Vide PT 2800 aminoisophthalic acid-halo- Att: MAMO TCV Advocates 05/12/2005 26/05/2005 benzene derivatives

Glaxo Wellcome House, Filing Date: 27/05/2005 Muscarinic acetylcholine Glaxo Group Limited Berkeley Avenue, Warrant signed on 2801 Rec: 4073/4 dt Wef: 28/05/2004 Vide PT 2801 receptor antagonists Att: SS & Co. Greenford, Middlesex, 05/12/2005 30/05/2005 UB6 ONN, Great Britain

Filing Date: 27/05/2005 Astrazeneca AB S - 151 85 Sodertalje, Warrant signed on 2802 Quinazoline derivatives Rec: 4075/6 dt Wef: 04/05/2004 Vide PT 2802 Att: SS & Co. Sweden 21/12/2005 30/05/2005

Pyrazole derivatives 126, East Lincoln Filing Date: 27/05/2005 compositions containing Merck & Co Inc. Warrant signed on 2804 Avenue, Railway, NJ Rec: 4058/9 dt Wef: 01/06/2004 Vide PT 2804 such compounds and Att: Dr. M. Chetcuti Cauchi 21/12/2005 07065 - 0907, USA 27/05/2005 methods of use

Filing Date: 31/05/2005 Wef: 05/06/2004 AstraZeneca AB S - 151 85 Sodertalje, Warrant signed on 2807 Chemical compounds Rec: 4112/3 dt Wef: 16/10/2004 Vide PT 2807 Att: SS & Co. Sweden 21/12/2005 03/05/2005 Wef: 12/02/2005

Yakult Honsha, 1-19, Higashi, Shimbashi l- Filing Date: 31/05/2005 Kabushiki Kaisha Warrant signed on 2808 Irinotecan formulation chome, Minato-ku, Rec: 4120/1 dt Wef: 01/06/2004 Vide PT 2808 Attn: CC Advocates 21/12/2005 Tokyo 105 - 8660, 31/05/2005 Japan

N - (2-Benzyl) - 2 - 126, East Lincoln Filing Date: 01/06/2005 Phenylbutanamides as Merck & Co Inc. Warrant signed on 2809 Avenue, Rahway, NJ Rec: 4144/5 dt Wef: 07/06/2004 Vide PT 2809 androgen receptor Att: Dr. M. Chetcuti Cauchi 21/12/2005 07065 - 0907, USA 01/06/2005 modulators

126, East Lincoln Filing Date: 02/06/2005 Merck & Co Inc. Warrant signed on 2810 HIV integrase inhibitors Avenue, Rahway, NJ Rec: 4192/3 dt Wef: N/A Vide PT 2810 Att: Dr. M. Chetcuti Cauchi 11/01/2007 07065 - 0907, USA 02/06/2004

Removal of ammonia and Filing Date: 02/06/2005 water from mixtures formed BASF Aktiengesellschaft 67056 Ludwigshafen, Warrant signed on 2811 Rec: 4211/2 dt Wef: 02/06/2004 Vide PT 2811 in the preparation of Att: SS & Co. Germany 21/12/2005 03/06/2005 polyamides Substituted aryl and heteroaryl derivatives as 10166, Nancy Ridge Filing Date: 03/06/2005 modulators of metabolism Arena Pharmaceuticals Inc. Warrant signed on 2812 Drive, San Diego, Rec: 4208/9 dt Wef: 04/06/2004 Vide PT 2812 and the prophylaxis and Att: Dr. M. Chetcuti Cauchi 21/12/2005 California, 92121, USA 03/06/2005 treatment of disorders related thereto

901, Gateway Crystalline form of a Boulevard, South San Filing Date: 06/06/2005 Theravance Inc. Warrant signed on 2813 substituted pyrrolidine Francisco, CA94080, Rec: 4246/7 dt Wef: 10/06/2004 Vide PT 2813 Att: SS & Co. 21/12/2005 compound United States of 08/06/2005 America

235 East 42nd Street, Filing Date: 06/06/2005 Benzimidazolone carboxylic Pfizer Inc. New York, New York Wef: 15/06/2004 Warrant signed on 2814 Rec: 4249/50 dt Vide PT 2814 acid derivatives Att: SS & Co. 10017, United States of Wef: 02/09/2004 21/12/2005 08/06/2005 America

436 Cambridge Science Park, Millon Road, Cambridge, CB4 0QA, Astex Techology Limited United Kingdom & Astex Therapeutics Limited Sardinia House, Filing Date: 06/06/2005 & Cancer Research Sardinia Street, Warrant signed on 2815 Pharmaceutical compounds Rec: 4252/3 dt Wef: 08/06/2004 Vide PT 2815 Technology Limited & The London WC2A 3NL, 24/12/2006 08/06/2005 Institute of Cancer Research United Kingdom & Att: SS & Co. Royal Cancer Hospital, 123 Old Brompton Road, London, Sw7, 3RP, United Kingdom

3-B-D ribofuranosylthiazolo 3115 Merryfield Row, Filing Date: 06/06/2005 [4-5 -d] pyrimidine Analys Pharmaceuticals Inc. Warrant signed on 2816 San Diego, California Rec: 4233/4 dt Wef: 07/06/2004 Vide PT 2816 nucleosides and uses Att: SS & Co. 03/07/2006 92121, USA 08/06/2005 thereof

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 08/06/2005 Glaxo Group Limited Wef: 09/06/2004 Warrant signed on 2817 Pyrrolopyridine derivatives Greenford Rec: 4266/7 dt Vide PT 2817 Att: SS & Co. Wef: 11/11/2004 21/12/2005 Middlesex UB6 ONN, 08/06/2005 Great Britain

Filing Date: 08/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2818 New compounds Rec: 4262/3 dt Wef: 15/06/2004 Vide PT 2818 Att: SS & Co. Sweden 21/12/2005 08/06/2005 Filing Date: 08/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2819 New compounds Rec: 4259/60 dt Wef: 15/06/2004 Vide PT 2819 Att: SS & Co. Sweden 21/12/2005 08/06/2005

One Franklin Plaza, Smithkline Beecham P.O. Box 7929, Filing Date: 08/06/2005 Apparatus and method for Wef: 09/06/2004 Warrant signed on 2820 Corporation Philadelphia, PA Rec: 4256/7 dt Vide PT 2820 pharmaceutical production Wef: 25/10/2004 21/12/2005 Att: SS & Co. 19101, United States of 08/06/2005 America

Heterocyclic derivatives for 11388 Sorrento Valley Filing Date: 09/06/2005 the treatment of Avanir Pharmaceuticals Warrant signed on 2822 Road, Suite 200, San Rec: 4438/9 dt Wef: 09/06/2004 Vide PT 2822 hyperlipidemia and related Att: SS & Co. 21/12/2005 Diego, CA 92121, USA 15/06/2005 diseases

Small molecules for the 11388 Sorrento Valley Filing Date: 09/06/2005 treatment of Avanir Pharmaceuticals Warrant signed on 2823 Road, Suite 200, San Rec: 4441/2 dt Wef: 09/06/2004 Vide PT 2823 hypercholesterolemia and Att: SS & Co. 21/12/2005 Diego, CA 92121, USA 15/06/2005 related diseases

Mediators of reverse 11388 Sorrento Valley Filing Date: 09/06/2005 cholesterol transport for the Avanir Pharmaceuticals Wef: 09/06/2004 Warrant signed on 2824 Road, Suite 200, San Rec: 4443/4 dt Vide PT 2824 treatment of Att: SS & Co. Wef: 01/04/2005 21/12/2005 Diego, CA 92121, USA 15/06/2005 hypercholesterolemia

2-1 Toranomon 2- Chome, Murato-Ku, Japan Tobacco Inc. & Mr Tokyo 105-8422, Japan Filing Date: 13/06/2005 Wef: 11/06/2004 Pyrimidine compound and Warrant signed on 2825 Toshituki SAKAI & 28-11, Kowaki-cho, Rec: 4446/7 dt Wef: 10/11/2003 Vide PT 2825 medical use thereof 21/12/2005 Att: SS & Co. Matsugasaki, Sakyo - 15/06/2005 Wef: 10/11/2004 ku, Kyoto-shi, Kyoto 606-0957, Japan

Filing Date: 13/06/2005 Novel tetracyclic Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2826 Rec: P585501 dt Wef: 14/06/2004 Vide PT 2826 tetrahydrofuran derivatives Att: EMD Advocates 2340 Beerse, Belgium 21/12/2005 13/06/2005

Alpha crystalline form of 12, Place de la strontium ranelate a Filing Date: 14/06/2005 Les Laboratoires Servier Defense, 92415 Warrant signed on 2828 process for its preparation Rec: 4455/6 dt Wef: 30/09/2004 Vide PT 2828 Att: SS & Co. Coubevoie Cedex, 03/04/2006 and pharmaceutical 15/06/2005 France compositions containing it

GlaxoSmithKline Biological Rue de L' Institute 89, B- Filing Date: 14/06/2005 Wef: 16/06/2004 Warrant signed on 2829 Vaccine SA 1330 Rixensart, Rec: 4457/8 dt Vide PT 2829 Wef: 26/04/2004 11/01/2006 Att: SS & Co Belgium 15/06/2005 Filing Date: 14/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2830 Chemical compounds Rec: 4460/1 dt Wef: 24/06/2004 Vide PT 2830 Att: SS & Co. Sweden 11/01/2006 15/06/2005

Filing Date: 14/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2831 New compounds Rec: 4463/4 dt Wef: 24/06/2004 Vide PT 2831 Att: SS & Co. Sweden 11/01/2006 15/06/2005

Filing Date: 14/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2832 Chemical compounds Rec: 4466/7 dt Wef: 24/06/2004 Vide PT 2832 Att: SS & Co. Sweden 11/01/2006 15/06/2005

Use of a pharmaceutical composition comprising Zugerstrasse 8, CH- Filing Date: 14/06/2005 Galderma S.A. Warrant signed on 2833 calcitriol and clobetasol 6330 Cham, Rec: 4428/9 dt Wef: 17/06/2004 Vide PT 2833 Att: SS & Co. 11/01/2006 propionate for the treatment Switzerland 15/06/2005 of psoriasis

P.O. Box 4000, Route Six-membered heterocycles Bristol-Myers Squibb 206 and Province Line Filing Date: 14/06/2005 Wef: 15/06/2004 Warrant signed on 2834 useful as serine protease Company Road, Princeton, New Rec: 4430/1 dt Vide PT 2834 Wef: 24/06/2005 21/12/2005 inhibitors Att: MAMO TCV Advocates Jersey 08543- 15/06/2005 4000,U.S.A.

P.O. Box 4000, Route Five-membered Bristol-Myers Squibb 206 and Province Line Filing Date: 14/06/2005 Wef: 15/06/2004 Warrant signed on 2835 heterocycles useful as Company Road, Princeton, New Rec: 4433/4 dt Vide PT 2835 Wef: 24/05/2005 21/12/2005 serine protease inhibitors Att: MAMO TCV Advocates Jersey 08543- 15/06/2005 4000,U.S.A.

Composition in the form of a spray comprising a Zugerstrasse 8, CH- Filing Date: 15/06/2005 combination of Galderma S.A. Warrant signed on 2836 6330 Cham, Rec: 4487/8 dt Wef: 17/06/2004 Vide PT 2836 pharmaceutical active Att: SS & Co. 11/01/2006 Switzerland 15/06/2005 ingredients, an alcohol phase and an oily phase

Composition in spray form Zugerstrasse 8, CH- Filing Date: 15/06/2005 Galderma S.A. Warrant signed on 2837 comprising a combination 6330 Cham, Rec: 4484/5 dt Wef: 17/06/2004 Vide PT 2837 Att: SS & Co. 11/01/2006 of actives and an oily phase Switzerland 15/06/2005

Pharmaceutical Zugerstrasse 8, CH- Filing Date: 15/06/2005 compositions comprising a Galderma S.A. Warrant signed on 2838 6330 Cham, Rec: 4481/2 dt Wef: 17/06/2004 Vide PT 2838 silicone agent and two Att: SS & Co. 11/01/2006 Switzerland 15/06/2005 solubilized active principles Glaxo Wellcome House, Berkeley Avenue, Filing Date: 16/06/2005 Glaxo Group Limited Warrant signed on 2839 Novel compound Greenford Rec: 4516/7 dt Wef: 18/06/2004 Vide PT 2839 Att: SS & Co. 11/01/2006 Middlesex UB6 ONN, 17/06/2005 Great Britain

280 East Grand Filing Date: 16/06/2005 Compounds, compositions Cytokinetics Inc. Avenue, South San 2840 Rec: 4519/20 dt Wef: 17/06/2004 Warrant signed on 11/1/06 Vide PT 2840 and methods Att: SS & Co. Francisco CA94080, 17/06/2005 USA

Novel spiroindoline or spiroisoquinoline 6166 Nancy Ridge Filing Date: 17/06/2005 Aroma Pharmaceuticals Inc. Warrant signed on 2841 compounds, methods of Drive, San Diego, Rec: 4552/3 dt Wef: N/A Vide PT 2841 Att: Dr. Maria Chetcuti Cauchi 11/01/2007 use and compositions California 92121, USA 17/06/2005 thereof

Modified release 909 Third Avenue, New Filing Date: 17/06/2005 Forest Laboratories, Inc. Warrant signed on 2842 formulations of nemantine York, NY 10022-4731, Rec: 4555/6 dt Wef: 17/06/2004 Vide PT 2842 Att: Dr. Maria Chetcuti Cauchi 11/01/2006 oral dosage formulations USA 17/06/2005

Eckenheimer Immediate release Merz Pharma GmbH & Co. Filing Date: 17/06/2005 Landstrasse 100, D - Warrant signed on 2843 formulations of nemantine KGAA Rec: 4558/9 dt Wef: 17/06/2004 Vide PT 2843 60318, Frankfurt Main, 11/01/2006 oral dosage forms Att: Dr. Maria Chetcuti-Cauchi 17/06/2005 Germany

610 Lincoln Street, Filing Date: 17/06/2005 Uses of kinase inhibitors GPC Biotech Inc. Waetham, Warrant signed on 2844 Rec: 4561/2 dt Wef: 18/06/2004 Vide PT 2844 and compositions thereof Att: Dr. Maria Chetcuti Cauchi Massachusetts 02451, 11/01/2006 17/06/2005 USA

Methods and compositions 3110 Cherry Palm Wef: 23/06/2004 Filing Date: 17/06/2005 for treating ophtalmic Sirion Therapeutics Inc. Drive, Suite 340 Wef: 19/11/2004 Warrant signed on 2845 Rec: 4594/5 dt Vide PT 2845 conditions with retinal Att: Dr. Maria Chetcuti Cauchi Tampa, Florida 33619, Wef: 11/03/2005 11/01/2006 20/06/2005 derivatives USA Wef: 18/04/2005

Novel unsaturated Filing Date: 21/06/2005 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 2846 tetracyclic tetrahydrafuran Rec: 4622/3 dt Wef: 23/06/2004 Vide PT 2846 Att: EMD Advocates 2340 Beerse, Belgium 11/01/2006 derivatives 21/06/2005

Glaxo Wellcome House, Berkeley Avenue, Filing Date: 21/06/2005 Glaxo Group Limited Warrant signed on 2847 Novel compounds Greenford Rec: 4645/6 dt Wef: 23/06/2004 Vide PT 2847 Att: SS & Co. 11/01/2006 Middlesex UB6 ONN, 21/04/2005 Great Britain Glaxo Wellcome House, Berkeley Avenue, Filing Date: 21/06/2005 Glaxo Group Limited Warrant signed on 2848 Novel compounds Greenford Rec: 4641/2 dt Wef: 23/06/2004 Vide PT 2848 Att: SS & Co. 11/01/2006 Middlesex UB6 ONN, 21/06/2005 Great Britain

Eastern Point Road, Substituted heteroaryl-and Filing Date: 21/06/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2849 phenylsulfamoyl Rec: 4638/9 dt Wef: 29/06/2004 Vide PT 2849 Att: SS & Co. 06340, United States of 11/01/2006 compounds 21/06/2005 America

Filing Date: 21/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2850 Chemical compounds Rec: 4635/6 dt Wef: 01/07/2004 Vide PT 2850 Att: SS & Co. Sweden 18/01/2006 21/06/2005

One Franklin Plaza, Smithkline Beecham P.O. Box 7929, Filing Date: 22/06/2005 Novel Indazole Warrant signed on 2851 Corporation Philadelphia, PA 19101, Rec: 4670/1 dt Wef: 24/06/2004 Vide PT 2851 carboxamides and their use 11/01/2006 Att: SS & Co. United States of 22/06/2005 America

Suite 2100 - 1040, Filing Date: 22/06/2005 Solid orally ingestible Wax Pharmaceuticals Inc West Georgia Street, Warrant signed on 2852 Rec: 4681/2 dt Wef: 22/06/2004 Vide PT 2852 formulations of tetrodotoxin Att: MAMO TCV Advocates Vancouver BC, Canada 11/01/2006 22/06/2005 V6E 1M4

Filing Date: 23/06/2005 Process for the preparation Zambon Group SpA Via della Clinica, 9 Warrant signed on 2853 Rec: 4704/5 dt Wef: 24/06/2004 Vide PT 2853 of gabapentin Att: SS & Co. 36100 - Vicenza, Italy 11/01/2006 23/06/2005

Tera Pharmaceuticals 5 Basel Street, PO Box Filing Date: 23/06/2005 Wef: 23/06/2004 Solid and crystalline Warrant signed on 2854 Industries Ltd 3/90, Petah Tiqva Rec: 4709/10 dt Wef: 18/10/2004 Vide PT 2854 ibandronic acid 11/01/2006 Att: Dr. Maria Chetcuti Cauchi 49131, Israel 23/06/2005 Wef: 16/06/2005

One Amgen Center Substituted hetrocyclic Filing Date: 23/06/2005 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2855 compounds and methods of Rec: 4712/3 dt Wef: 25/06/2004 Vide PT 2855 Att: Chetcuti Cauchi Advocates California 91320-1799, 11/01/2006 use 23/06/2005 USA

Quinazolineedione Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 24/06/2005 Warrant signed on 2856 derivatives as PARP Wef: N/A Vide PT 2856 Att: EMD Advocates 2340 Beerse, Belgium Rec: P585511dt 24/6/05 11/01/2006 inhibitors

Quinazolineedione Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 24/06/2005 Warrant signed on 2857 derivatives as PARP Wef: N/A Vide PT 2857 Att: EMD Advocates 2340 Beerse, Belgium Rec: P585511dt 24/6/05 11/01/2006 inhibitors

NV subsituted 2-Alkyl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 24/06/2005 Warrant signed on 2858 quinazolinone derivatives Wef: N/A Vide PT 2858 Att: EMD Advocates 2340 Beerse, Belgium Rec: P585511dt 24/6/05 11/01/2006 as PARP inhibitors NV pathalazine derivatives Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 24/06/2005 Warrant signed on 2859 Wef: N/A Vide PT 2859 as PARP inhibitors Att: EMD Advocates 2340 Beerse, Belgium Rec: P585511dt 24/6/05 11/01/2006

Filing Date: 28/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2860 Novel compounds Rec: 4773/4 dt Wef: 05/07/2004 Vide PT 2860 Att: SS & Co. Sweden 18/01/2006 28/06/2005

An inhalation device and a Filing Date: 28/06/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2861 method for assembling said Rec: 4776/7 dt Wef: 02/07/2004 Vide PT 2861 Att: SS & Co. Sweden 18/01/2006 inhalation device 28/06/2005

Human glucagon-like- P.O. Box 4000, Route peptide-1 modulators and Bristol-Myers Squibb 206 and Province Line Filing Date: 28/06/2005 Wef: 02/07/2004 Warrant signed on 2862 their use in the treatment of Company Road, Princeton, New Rec: 4779/80 dt Vide PT 2862 Wef: 26/05/2005 18/01/2006 diabetes and related Att: MAMO TCV Advocates Jersey 08543- 28/06/2005 conditions 4000,U.S.A.

P.O. Box 4000, Route Bristol-Myers Squibb 206 and Province Line Filing Date: 28/06/2005 Pyrrolotiazine kinase Wef: 28/06/2004 Warrant signed on 2863 Company Road, Princeton, New Rec: 4782/83 dt Vide PT 2863 inhibitors Wef: 23/09/2004 11/01/2006 Att: MAMO TCV Advocates Jersey 08543- 28/06/2005 4000,U.S.A.

P.O. Box 4000, Route Bristol-Myers Squibb 206 and Province Line Filing Date: 28/06/2005 Fused heterocyclic kinase Wef: 28/06/2004 Warrant signed on 2864 Company Road, Princeton, New Rec: 4785/6 dt Vide PT 2864 inhibitors Wef: 23/09/2004 11/01/2006 Att: MAMO TCV Advocates Jersey 08543- 28/06/2005 4000,U.S.A.

One Amgen Center Drive, Thousand Oaks, Imidazolo-related Amgen Inc. & Amgen SF California 91320, USA Filing Date: 28/06/2005 Warrant signed on 2865 compounds, composition L.L.C. & 1120 Rec: 4864/5 dt Wef: 28/06/2004 Vide PT 2865 11/01/2006 and methods for their use Att: B&M Patentbureau Veterans Boulevard, 04/07/2005 South San Francisco, CA 94080, USA

One Amgen Center Compounds, compositions Drive, Thousand Oaks, and methods for prevention Amgen Inc. & Amgen SF California 91320, USA Filing Date: 28/06/2005 and treatment of Warrant signed on 2866 L.L.C. & 1120 Rec: 4861/2 dt Wef: 28/06/2004 Vide PT 2866 inflammatory and 11/01/2006 Att: B&M Patentbureau Veterans Boulevard, 04/07/2005 Immunoregulatory disorders South San Francisco, and diseases CA 94080, USA One Amgen Center Tetrahydroquinazolin-4(3H)- Drive, Thousand Oaks, one related and Amgen Inc. & Amgen SF California 91320, USA Filing Date: 28/06/2005 tetrahydropyrido [2,3D] Warrant signed on 2867 L.L.C. & 1120 Rec: 4858/9 dt Wef: 28/06/2004 Vide PT 2867 pyrimidin-4-(3H)-one related 11/01/2006 Att: B&M Patentbureau Veterans Boulevard, 04/07/2005 compounds, composition South San Francisco, and methods for their use CA 94080, USA

Teva Pharmaceuticals Fine Strada Statale, Briantea Filing Date: 28/06/2005 Process for the preparation Warrant signed on 2868 Chemicals S.r.l. Km36, No 83 23892, Rec: 4839/40 dt Wef: 28/06/2004 Vide PT 2868 of tomoxetine 11/01/2006 Att: Chetcuti Cauchi Advocates Bulciago (LC), Italy 04/07/2005

Process for the optical Teva Pharmaceuticals Fine Strada Statale, Briantea Filing Date: 28/06/2005 Warrant signed on 2869 resolution and recycling of Chemicals S.r.l. Km36, No 83 23892, Rec: 4835/6 dt Wef: 28/06/2004 Vide PT 2869 11/01/2006 tomoxetine Att: Chetcuti Cauchi Advocates Bulciago (LC), Italy 04/07/2005

Process for the preparation Teva Pharmaceuticals Fine Strada Statale, Briantea Filing Date: 28/06/2005 Warrant signed on 2870 of atomoxetine Chemicals S.r.l. Km36, No 83 23892, Rec: 4832/3 dt Wef: 28/06/2004 Vide PT 2870 11/01/2006 hydrochloride Att: Chetcuti Cauchi Advocates Bulciago (LC), Italy 04/07/2005

An isolated atomoxetine impurity, process for the Teva Pharmaceuticals Fine Strada Statale, Briantea Filing Date: 28/06/2005 preparation of a Warrant signed on 2871 Chemicals S.r.l. Km36, No 83 23892, Rec: 4829/30 dt Wef: 28/06/2004 Vide PT 2871 atomoxetine impurities and 11/01/2006 Att: Chetcuti Cauchi Advocates Bulciago (LC), Italy 04/07/2005 their use as reference standards

Enantiomerically pure Teva Pharmaceuticals Fine Strada Statale, Briantea Filing Date: 28/06/2005 Warrant signed on 2872 atomoxetine and Chemicals S.r.l. Km36, No 83 23892, Rec: 4826/7 dt Wef: 28/06/2004 Vide PT 2872 11/01/2006 tomoxetine mandelate Att: Chetcuti Cauchi Advocates Bulciago (LC), Italy 04/07/2005

126, East Lincoln Filing Date: 30/06/2005 Merck & Co Inc. Wef: 02/07/2004 Warrant signed on 2873 CETP inhibitors Avenue, Rahway, NJ Rec: 4842/3 dt Vide PT 2873 Att: Chetcuti Cauchi Advocates Wef: 21/01/2005 18/01/2006 07065 - 0907, USA 04/07/2005

Glaxo Wellcome House, Filing Date: 30/06/2005 Glaxo Group Limited Berkeley Avenue, Warrant signed on 2874 Immunoglobulins Rec: 4846/7 dt Wef: 01/07/2004 Vide PT 2874 Att: SS & Co. Greenford, Middlesex 18/01/2006 04/07/2005 UB6 ONN, Great Britain

One Amgen Center Pyrrolo[2,3-d] pyrimidines Filing Date: 30/06/2005 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2875 that modulate ACK 1 and Rec: 4849/50 dt Wef: 29/06/2004 Vide PT 2875 Att: SS & Co. California 91320-1799, 11/01/2006 LCK activity 04/07/2005 USA One Amgen Center Filing Date: 30/06/2005 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2876 Furanopyrimidinces Rec: 4852/3 dt Wef: 29/06/2004 Vide PT 2876 Att: SS & Co. California 91320-1799, 11/01/2006 04/07/2005 USA

Crystals of 1,2 - Eisai R&D Management Co. 4 - 6-10 Koishikawa, Filing Date: 04/07/2005 dihdropyridine compound Warrant signed on 2877 Ltd Att: SS Bunkyo-ku, Tokyo, Rec: 4944/5 dt Wef: 07/06/2004 Vide PT 2877 and their production 18/01/2006 & Co. Japan 06/07/2005 process

Filing Date: 05/07/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2878 Compounds Rec: 4947/8 dt Wef: 05/07/2004 Vide PT 2878 Att: SS & Co. Sweden 18/01/2006 06/07/2005

Filing Date: 05/07/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2879 Inhaler device counter Rec: 4949/50 dt Wef: 05/07/2004 Vide PT 2879 Att: SS & Co. Sweden 18/01/2006 06/07/2005

Filing Date: 05/07/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2880 Inhaler device Rec: 4952/3 dt Wef: 05/07/2004 Vide PT 2880 Att: SS & Co. Sweden 18/01/2006 06/07/2005

Warner-Lambert Company 201 Tabor Road, Morris Filing Date: 05/07/2005 Wef: 08/07/2004 Warrant signed on 2881 Androgen modulators LLC Plains, New Jersey Rec: 4955/6 dt Vide PT 2881 Wef: 02/08/2004 18/01/2006 Att: SS & Co. 07950, USA 06/07/2005

Filing Date: 05/07/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2882 Novel compounds Rec: 4958/9 dt Wef: 08/07/2004 Vide PT 2882 Att: SS & Co. Sweden 18/01/2006 06/07/2005

Filing Date: 05/07/2005 Astrazeneca AB SE - 151 85 Sodertalje, Warrant signed on 2883 Pyrimidine derivatives Rec: 4961/2 dt Wef: 09/07/2004 Vide PT 2883 Att: SS & Co. Sweden 18/01/2006 06/07/2005

Process for Synthesis of 4- Lundbeck Pharmaceuticals Filing date: 06/07/2005 Via Quarta Strada 2, Warrant signed on: 2884 4' -Diamino-Diphenyl- Italy S.p.A. Rec. 4983/4 dt Wef: 07/07/2004 Vide PT 2884 35129 Padova, Italy 18/01/2006 Sulfone Att: SS & Co. 06/07/2005

Process for the Synthesis Lundbeck Pharmaceuticals Filing date: 06/07/2005 and Purification of 4- Via Quarta Strada 2, Warrant signed on: 2885 Italy S.p.A. Rec. 4985/6 dt Wef: 07/07/2004 Vide PT 2885 Trifluoromethylvaleropheno 35129 Padova, Italy 18/01/2006 Att: SS & Co. 06/07/2005 ne

Memantine as adjunctive 909 Third Avenue, New Filing Date: 07/07/2005 treatments to atypical Forest Laboratories, Inc. Warrant signed on 2886 York , NY 10022-4731, Rec: 5015/6 dt Wef: 09/07/2004 Vide PT 2886 antipsychotics in Att: Dr. M Chetcuti Cauchi 18/01/2006 USA 07/07/2005 shizophrenia patients One Amgen Center Filing Date: 08/07/2005 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2887 Therapeutic peptides Rec: 51171/8 dt Wef: 08/07/2004 Vide PT 2887 Att: J. Mifsud California 91320-1799, 18/01/2006 13/07/2005 USA

Siegfried Generics Filing Date: 12/07/2005 Granules of controlled Untere Bruhlstasse 4, Warrant signed on 2888 International AG Rec: 5136/7 dt Wef: 14/07/2004 Vide PT 2888 release of tamsulosin Zofingen, Switzerland 18/01/2006 Att: SS & Co. 13/07/2005

Eastern Point Road, Novel piperidyl derivatives Filing Date: 12/07/2005 Pfizer Products Inc. Groton, Connecticut Warrant signed on 2889 of quinazoline and Rec: 5140/1 dt Wef: 23/07/2004 Vide PT 2889 Att: SS & CO. 06340, United States of 24/02/2006 isoquinoline 13/07/2005 America

Wef: 15/07/2004 Condensed benzamide Wef: 28/12/2004 2-1 Toranomon 2- Filing Date: 12/07/2005 compounds and inhibitors Japan Tobacco, Inc. Wef: 28/04/2005 Warrant signed on 2890 Chome, Murato-Ku, Rec: 5143/4 dt Vide PT 2890 of vanilloid receptor Att: SS & Co. Wef: 22/07/2004 18/01/2006 Tokyo, Japan 105-8422 13/07/2005 subtype 1 (VB1) activity Wef: 06/01/2005 Wef: 12/05/2005

Cis-Diiodine - (Trans - L -1,2- Cyclohexa-ne diamine) Filing Date: 12/07/2005 Sicor Inc 19 Hughs Irvine, Wef: 12/07/2004 Warrant signed on 2891 platinum II complex and Rec: 5148/9 dt Vide PT 2891 Att: Dr. M Chetcuti Cauchi California 92618, USA Wef: 27/07/2004 18/01/2006 process for preparing high 13/07/2005 purity oxaliplatin

A process for preparing highly pure androstane 17- Via Del Garbounera Filing Date: 13/07/2005 S.N.I.F.F. Italia SPA beta-carboxylic acids and 30/32, Localita' Rec: 1320/7 dt Warrant signed on 2894 Att: Sterling Chemicals Malta Wef: N/A Vide PT 2894 androstane 17-beta- Solomeo Corciano - 08/03/2006 10/10/2007 Ltd carbothoic acid Perugia, Italy fluoromethyl estors

P.O Box 4000 Route 206 & Province Bristol-Myers Squibb Filing Date: 14/07/2005 Pyrrolo(oxo) quinolines as Line Road, Princeton, Warrant signed on 2895 Company Rec: 5199/200 dt Wef: 14/07/2005 Vide PT 2895 5HT ligands New Jersey 08543- 18/01/2006 Att: MAMO TCV Advocates 14/07/2005 4000, United States of America

P.O Box 4000 Route 206 & Province Bristol-Myers Squibb Filing Date: 14/07/2005 Pyrrolo(oxo) Isoquinolines Line Road, Princeton, Warrant signed on 2896 Company Rec: 5196/7 dt Wef: 14/07/2004 Vide PT 2896 as 5HT ligands New Jersey 08543- 18/01/2006 Att: MAMO TCV Advocates 14/07/2005 4000, United States of America One Amgen Center 1,2,3,4 - Tetrahydropyrazin - Filing Date: 15/07/2005 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 2897 2 - YL acetamides and Rec: 5232/3 dt Wef: 15/07/2004 Vide PT 2897 Att: Dr M Chetcuti Cauchi California 91320-1799, 18/01/2006 methods of use 15/07/2005 USA

Agent for the treatment of 2-1 Toranomon 2- Filing Date: 15/07/2005 Japan Tobacco Inc. Wef: 16/07/2004 Warrant signed on 2898 prevention of diabetes, Chome, Murato-Ku, Rec: 5247/8 dt Vide PT 2898 Att: Bezzina & Mifsud Wef: 02/08/2004 03/02/2006 obesity or arteriosclerois Tokyo, Japan 105-8422 18/07/2005

4-arylmorpholin- 3 - one Filing Date: 19/07/2005 derivatives, preparation Sanofi - Aventis 174 Avenue de France, Warrant signed on 2899 Rec: 5264/5 dt Wef: 23/07/2005 Vide PT 2899 thereof and therapeutic Att: SS & Co. FR-75013 Paris, France 03/02/2006 20/07/2005 application thereof

Glaxo Wellcome House, Filing Date: 19/07/2005 Glaxo Group Limited Berkeley Avenue, Wef: 28/07/2004 Warrant signed on 2900 Novel compounds Rec: 5267/8 dt Vide PT 2900 Att: SS & Co. Greenford, Middlesex Wef: 08/07/2005 03/02/2006 20/07/2005 UB6 ONN, Great Britain

58, South Service Road, Suite 110, Filing Date: 19/07/2005 Imidazotriazines as protein OSI Pharmaceuticals Inc Warrant signed on 2901 Melville, NY 11747, Rec: 5270/1 dt Wef: 20/07/2004 Vide PT 2901 kinase inhibitors. Att: SS & Co. 03/02/2006 United States of 20/07/2005 America MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No 126 East Lincoln Avenue, Potassium channel Merck & Co. Inc. Filing Date: 20/07/2005 Warrant signed on 2902 Rahway, New Jersey Wef: 29/07/2004 Vide PT 2902 inhibitors Att: Dr M. Chetcuti Cauchi Rec: 5291/2 dt 20/07/2005 03/02/2006 07065, USA

One Procter & Gamble Biphosphonate The Procter & Gamble Plaza, Cinannati, Ohio Filing Date: 21/07/2005 Warrant signed on 2903 compositions and their Company Wef: 23/07/2004 Vide PT 2903 45202, United States of Rec: 5320/1 dt 21/07/2005 03/02/2006 methods of use Att: SS & Co. America

Use of cyanine dyes for the diagnosis of disease Schering AG Filing Date: 22/07/2005 Warrant signed on 2904 Berlin 13342, Germany Wef: 22/07/2004 Vide PT 2904 associated with Att: MAMO TCV Advocates Rec: 5332/3 dt 22/07/2005 03/02/2006 angiogenesis

TEVA Pharmaceutical Fine Strada Statale Briantea, Polymorphs of atom Filing Date: 22/07/2005 Warrant signed on 2905 Chemicals S.r.l. KM 36, No 83, 23892 Wef: 22/07/2004 Vide PT 2905 oxetine hydrochloride Rec: 5348/9 dt 22/07/2005 03/02/2006 Att: Dr M. Chetcuti Cauchi Bulciago (LC), Italy

Therapeutic composition Merz Pharma Gmbh & Co Eckenkeiner Landstrasse Filing Date: 22/07/2005 Warrant signed on 2906 with a botulinium- KGAA 100, D-60318 Frankfurt, Wef: 26/072004 Vide PT 2906 Rec: 5352/3 dt 22/07/2005 03/02/2006 neurotoxin Att: Dr M. Chetcuti Cauchi Germany

One Amgen Center, Furanopyridine Amgen Inc. Filing Date: 22/07/2005 Warrant signed on 2907 Thousand Oaks, CA 91320- Wef: 23/07/2004 Vide PT 2907 derivatives and methods Att: Dr M. Chetcuti Rec: 5355/6 dt 22/07/2005 03/02/2006 1799, USA

Substituted aryl-amine One Amgen Center, Amgen Inc. Filing Date: 22/07/2005 Warrant signed on 2908 derivatives and methods Thousand Oaks, CA 91320- Wef: 22/07/2004 Vide PT 2908 Att: Dr M. Chetcuti Rec: 5358/2 dt 22/07/2005 03/02/2006 of use 1799, USA

Diarylmethyl piperazine AstiaZeneca AB S-15185 Sodertalje, Filing Date: 26/07/2005 Wef: 02/08/2004 Warrant signed on 2914 derivatives, preparations Vide PT 2914 Att: SS & Co Sweden Rec: 5418/9 dt 28/07/2005 Wef: 18/08/2004 24/02/2006 thereof and uses therof

A Process for the Sicor Inc. Wef: 27/07/2004 19 Hughes, Irvine, Filing Date: 27/07/2005 Warrant signed on 2915 Preparations of 7α- Att: Chetcuti Cauchi Wef: 09/08/2004 Vide PT 2915 California 92618, U.S.A. Rec: 5411/2 dt 28/07/2005 03/02/2006 Alkylated 19-Norsteroids Advocates Wef:06/12/2004

Glaxo Smithkline Rue de l'Institut 89, B-1330 Filing Date: 03/08/2005 Warrant signed on 2916 Vaccine Biologicals s.a Wef: 05/08/2004 Vide PT 2916 Rixensart, Belgium Rec: 5503/4 dt 03/08/2005 24/02/2006 Att: SS & Co Oxazolidinones Pharmacia & Upjohn 301 Henrietta Street, Filing Date: 03/08/2005 Warrant signed on 2917 Containing oxindoles as Company LLC Kalamazoo, Michigan Wef: 06/08/2004 Vide PT 2917 Rec: 5506/7 dt 03/08/2005 24/02/2006 antibacterial agnets Att: SS & Co 49001, USA

One Amgen Center Drive, Amgen Inc. Filing Date: 04/08/2005 Warrant signed on 2918 Antibodies to DKK-1 Thousand Oaks, CA 91320- Wef: 04/08/2004 Vide PT 2918 Att: Dr M. Chetcuti Cauchi Rec: 5556/7 dt 05/08/2005 24/02/2006 1799, USA

Novel quinoxalinone norepinephrine reuptake Warner- Lambert Company 201 Tabor Road, Morris Inhibitors for the Filing Date: 08/08/2005 Warrant signed on 2920 LLC Plains, New Jersey 67950, Wef: 09/08/2004 Vide PT 2920 treatment of central Rec: 5599/00 dt 08/08/2005 24/02/2006 Att: SS & Co USA nervouse system disorders

Compounds which Glaxo Wellcome House, potentiate glutamate Glaxo Group Limited Berkeley Avenue, Filing Date: 08/08/2005 Wef: 09/08/2004 Warrant signed on 2921 Vide PT 2921 receptor and uses therof Att: SS & Co Greenford, Middlesex UB6 Rec: 5601/2 dt 08/08/2005 Wef: 26/04/2005 24/02/2006 in medicine ONN, Great Britian

901, Gateway Boulevard, Crystalline form of a Theravance Inc. Filing Date: 09/08/2005 Warrant signed on 2922 South San Francisco, CA, Wef: 16/08/2004 Vide PT 2922 biphenyl compounds Att: SS & Co Rec: 5642/3 dt 09/08/2005 28/02/2006 94080, USA

Triazolopyridinylsulfanyl Pfizer Inc. 235 East 42nd Street, New Filing Date: 09/08/2005 Wef: 12/08/2004 Warrant signed on 2923 Derivatives as P38 MAP Vide PT 2923 Att: SS & Co York 10017, USA Rec: 5639/40 dt 09/08/2005 Wef: 17/06/2005 24/02/2006 kinase inhibitors

Inhibitors of the hepatitis C virus RNA- dependent RNA polymerase and Pfizer Inc. 235 East 42nd Street, New Filing Date: 09/08/2005 Warrant signed on 2924 Wef: 18/08/2004 Vide PT 2924 composition and Att: SS & Co York 10017, USA Rec: 5636/7 dt 09/08/2005 28/02/2006 treatments using the same

Enantiomers of selected AstraZeneca AB S-15185 Sodertalje, Filing Date: 09/08/2005 Warrant signed on 2925 fused heterocyclics and Wef: 18/08/2004 Vide PT 2925 Att: SS & Co Sweden Rec: 5632/4 dt 09/08/2005 28/02/2006 uses thereof

Selected fused AstraZeneca AB S-15185 Sodertalje, Filing Date: 09/08/2005 Warrant signed on 2926 heterocyclics and uses Wef: 18/08/2004 Vide PT 2926 Att: SS & Co Sweden Rec: 5628/30 dt 09/08/2005 28/02/2006 thereof

P.O. Box 4000, Route 206 Bristol- Myers Squibb Inhibitors of HCV & Province Line Road Filing Date: 09/08/2005 Wef: 09/08/2004 Warrant signed on 2927 Company Vide PT 2927 replication Primceton, New Jersey Rec: 5613/4 dt 09/08/2005 Wef: 11/03/2005 24/02/2006 Att: MAMO TCV Advocates 08543-4000, USA Use of TPO mimetic Janssen Pharmaceutica compounds and N.V., Turnhoutseweg 30, B-2340 Filing Date: 10/08/2005 2928 pharmaceuticals Wef: 16/08/2004 WITHDRAWN Vide PT 2928 Att: EMD Advocates Beerse, Belgium Rec: 5673/4 dt 10/08/2005 compositions in the treatment of Anemia

Compounds and Novartis AG Lichtsrasse 35, 4056 Filing Date: 11/08/2005 Warrant signed on 2929 compositions useful as Wef: 17/08/2004 Vide PT 2929 Att: SS & Co Basel, Switzerland Rec: 5708/9 dt 11/08/2005 28/02/2006 cathepsin S inhibitors

AstraZeneca AB S-15185 Sodertalje, Filing Date: 11/08/2005 Warrant signed on 2931 Novel Compounds Wef: 24/08/2004 Vide PT 2931 Att: SS & Co Sweden Rec: 5698/9 dt 11/08/2005 28/02/2006

Substituted biaryl 35 Northeast Industrial Neurogen Corporation Filing Date: 11/08/2005 Wef: 13/08/2004 Warrant signed on 2932 piperazinyl - pyridine Road, Brandford, Vide PT 2932 Att: SS & Co Rec: 5701/2 dt 11/08/2005 Wef: 05/01/2005 24/02/2006 analogues Connecticut 06405, USA

Isoindolone compounds S-15185 Sodertalje, AstraZeneca AB & NPS and their use as Sweden & 6850 Goreway Filing Date: 11/08/2005 Wef: 13/08/2004 Warrant signed on 2933 Pharmaceuticals Inc. Vide PT 2933 metabotropic Glutamate Drive, Mississauga, Ontario Rec: 5692/3 dt 11/08/2005 Wef: 27/05/2005 24/02/2006 Att: SS & Co receptor potentiators L4V1V7 Canada

Smithkline Beecham One Franklin Plaza, Filing Date: 12/08/2005 Warrant signed on 2934 Chemical compounds Corporation Wef: 16/08/2004 Vide PT 2934 Philadelphia, PA19101, Rec: 5843/4 dt 27/08/2005 28/02/2006 Att: SS & Co USA

Banyu Pharmaceutical Co. 2-3, Nihorebashi, Honchu 2- Fused ring 4- Filing Date: 12/08/2005 Warrant signed on 2935 Ltd Chome, Chuo-Ku, Tokyo Wef: N/A Vide PT 2935 oxopyrimidine derivative Rec: 5840/1 of 22/08/2005 23/10/2007 Att: SS & Co 103-8416, Japan

One Amgen Center Drive Substituted benzofused Amgen Inc. Filing Date: 12/08/2005 Warrant signed on 2936 Thousand Oaks, CA 91320- Wef: 13/08/2004 Vide PT 2936 heterocycles Att: Dr M. Chetcuti Cauchi Rec: 5744/5 dt 16/08/2005 24/02/2006 1799, USA

Process for the Sicor Inc. 19 Hughes, Irvine, Filing Date: 12/08/2005 Wef:12/08/2004 Warrant signed 2937 Preparation of 3-oximino Vide PT 2937 Att: Dr M. Chetcuti Cauchi California 92618, U.S.A. Rec: 5741/2 dt 16/08/2005 Wef:15/09/2004 on24/02/2006 Steroids

One Amgen Center Drive, Amgen Inc. Filing Date: 12/08/2005 Warrant signed on 2938 Bisaryl - Sulfonamides Thousand Oaks, CA 91320- Wef: 12/08/2004 Vide PT 2938 Att: J. Mifsud Rec: 5767/8 dt 17/08/2005 24/02/2006 1799, USA Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 16/08/2005 Warrant signed on 2939 Novel Compounds Wef: 16/08/2004 Vide PT 2939 Att: SS & Co Greenford, Middlesex UB6 Rec: 5738/9 dt 16/08/2005 28/02/2006 0NN, Great Britian

Novel Biaromatic compounds that active PPAR type receptors, Galderma Research & 635, Route des Lucioles Filing Date: 16/08/2005 Warrant signed on 2940 and use thereof in Development S.N.C BP87 06902 Sophia Wef: 17/08/2004 Vide PT 2940 Rec: 5759/60 dt 16/08/2005 28/02/2006 cosmetic or Att: SS & Co Antipolis Cedex, France pharmaceutical compositions

Novel Biaromatic compounds that activate PPAR type receptors, Galderma Research & 635, Route des Lucioles Filing Date: 16/08/2005 Warrant signed on 2941 and use thereof in Development S.N.C BP87 06902 Sophia Wef: 17/08/2004 Vide PT 2941 Rec: 5756/7 dt 16/08/2005 28/02/2006 cosmetic or Att: SS & Co Antipolis Cedex, France pharmaceutical compositions

Methods and One Amgen Center Drive, Filing Date: 19/08/2005 compositions for Amgen Inc. Warrant signed on 2942 Thousand Oaks, CA 91320- Rec: P285518 dt Wef: 20/08/2004 Vide PT 2942 treating allergic Att: Dr M. Chetcuti Cauchi 28/02/2006 1799, USA 19/08/2005 inflammation

Raheens East, Ringaskiddy Recordati Ireland Limited Filing Date: 23/08/2005 Warrant signed on 2943 Lercanidipine Salts Co. Cork, Wef: 24/08/2004 Vide PT 2943 Att: SS & Co Rec: 5876/7 dt 23/08/2005 28/02/2006 Ireland

Arylsulphonylstilbene Merck Sharp & Dohme Hertford Road, Hoddesdon, derivatives for treatment Filing Date: 23/08/2005 Warrant signed on 2944 Limited Hertfordshire EN119BU, Wef: 27/08/2004 Vide PT 2944 of insomnia and related Rec: 5886/7 of 24/08/2005 28/02/2006 Att: Dr M. Chetcuti Cauchi UK conditions

Solid and crystalline Teva Pharmaceutical 5 Basel Street, P.O. Box ibandronate sodium and Filing Date: 23/08/2005 Wef: 23/08/2004 Warrant signed on 2945 Industries Ltd 3190, Petah Tiqva 49131, Vide PT 2945 processes for Rec: 5883/4 dt 24/08/2005 Wef: 16/06/2005 28/02/2006 Att: Dr M. Chetcuti Cauchi Israel preparation thereof

Synthesis of Idarubicin Sicor Inc. 19 Hughes, Irvine, Filing Date: 23/08/2005 Wef: 23/08/2004 Warrant signed on 2946 Vide PT 2946 Aglycone Att: Dr M. Chetcuti Cauchi California 92618, U.S.A. Rec: 5880/1 dt 24/08/2005 Wef: 01/09/2004 28/02/2006

Pyrazole - substituted aminoheteroaryl Pfizer Inc. 235 East 42nd Street, New Filing Date: 24/08/2005 Wef: 26/08/2004 Warrant signed on 2947 Vide PT 2947 compounds as protein Att: SS & Co York 10017, USA Rec: 5920/1 dt 24/08/2005 Wef: 14/06/2005 28/02/2006 kinase Inhibitors Enantiomerically pure aminoheteroaryl Pfizer Inc. 235 East 42nd Street, New Filing Date: 24/08/2005 Wef: 26/08/2004 Warrant signed on 2948 Vide PT 2948 compounds as protein Att: SS & Co York 10017, USA Rec: 5917/8 dt 24/08/2005 28/02/2006 kinase inhibitors

AstraZeneca AB S-15185 Sodertalje, Filing Date: 24/08/2005 Warrant signed on 2949 Chemical Compounds Wef: 01/09/2004 Vide PT 2949 Att: SS & Co Sweden Rec: 5914/5 dt 24/08/2005 16/03/2006

Glycerol branched polyethylene glycol Pharmacia & Upjohn 301 Henrietta Street, human growth hormone Filing Date: 24/08/2005 Warrant signed on 2950 Company LLC Kalamazoo, Michigan Wef: 31/08/2004 Vide PT 2950 conjugates, process for Rec: 5911/2 dt 24/08/2005 28/02/2006 Att: SS & Co 49001, USA their preparation, and methods of use thereof

Pfizer Inc. 235 East 42nd Street New Filing Date: 24/08/2005 Warrant signed on 2951 Chemical compounds Wef: 24/08/2004 Vide PT 2951 Att: SS & Co. York 10017, USA Rec: 5908/9 dt 24/08/2005 16/05/2006

AstraZeneca AB S-15185 Sodertalje, Filing Date: 26/08/2005 Wef: 28/08/2004 Warrant signed on 2952 Compounds Vide PT 2952 Att: SS & Co Sweden Rec: 5978/9 dt 29/08/2005 Wef: 08/02/2005 28/02/2006

Novartis AG Lichtsrasse 35, 4056 Filing Date: 26/08/2005 Warrant signed on 2953 Pyrimidine derivatives Wef: 27/08/2004 Vide PT 2953 Att: SS & Co Basel, Switzerland Rec: 5975/6 dt 29/08/2005 28/02/2006

Novartis AG Lichtsrasse 35, 4056 Filing Date: 26/08/2005 Warrant signed on 2954 Pyrimidine derivatives Wef: 27/08/2004 Vide PT 2954 Att: SS & Co Basel, Switzerland Rec: 5972/3 dt 29/08/2005 28/02/2006

N-2 Adamanatayl - 2- phenoxy - acetamide Janssen Pharmaceutica derivatives as 11-beta N.V., Turnhoutseweg 30, B-2340 Filing Date: 29/08/2005 Warrant signed on 2956 Wef: 30/08/2004 Vide PT 2956 hydroxysteroid Att: EMD Advocates Beerse, Belgium Rec: 5963/4 dt 29/08/2005 16/03/2006 dehydrogenase inhibitors

Tricyclic adamantylamide Janssen Pharmaceutica derivatives as 11-Beta N.V., Turnhoutseweg 30, B-2340 Filing Date: 29/08/2005 Warrant signed on 2957 Wef: 30/08/2004 Vide PT 2957 hydroxysteroid Att: EMD Advocates Beerse, Belgium Rec: 5960/1 dt 29/08/2005 16/03/2006 dehydrogenase inhibitors

Epimerisation of allylic LEO Pharma A/S Industriparker 55, DK-2750 Filing Date: 30/08/2005 Warrant signed on 2958 Wef: 01/09/2004 Vide PT 2958 alcohols Att: SS & Co Ballerup, Denmark Rec: 6007/9 dt 30/08/2005 16/03/2006 Glaxo Wellcome House, Wef: 31/08/2004 Fused tricyclic Glaxo Group Limited Berkeley Avenue, Filing Date: 30/08/2005 Warrant signed on 2959 Wef: 12/04/2005 Vide PT 2959 derivatives Att: SS & Co Greenford, Middlesex UB6 Rec: 6023/4 dt 30/08/2005 16/03/2006 Wef: 21/07/2005 0NN, Great Britain

Wef: 30/08/2004 AstraZeneca AB S-15185 Sodertalje, Filing Date: 30/08/2005 Warrant signed on 2960 Novel compounds Wef: 15/12/2004 Vide PT 2960 Att: SS & Co Sweden Rec: 6020/1 dt 30/08/2005 16/03/2006 Wef: 06/04/2005

New inidazopyridine compounds, a process 12, Place de La Defense, for their preparation and Les Laboratories Servier Filing Date: 30/08/2005 Warrant signed on 2961 92415 Courbevoie Cedex, Wef: 31/08/2004 Vide PT 2961 pharmaceutical Att: SS & Co Rec: 6018/9 dt 30/08/2005 16/03/2006 France compositions containing them

Wef: 03/09/2004 AstraZeneca AB S-15185 Sodertalje, Filing Date: 30/08/2005 Warrant signed on 2962 Benzamide compounds Wef: 08/02/2005 Vide PT 2962 Att: SS & Co Sweden Rec: 6015/6 dt 30/08/2005 16/03/2006 Wef: 29/03/2005

Mercaptoamides As 58 South Service Road, OSI Pharmaceuticals Inc. Filing Date: 30/08/2005 Warrant signed on 2963 histone Deacetylase Suite 110, Melville NY Wef: 02/09/2004 Vide PT 2963 Att: SS & Co Rec: 6011/3 dt 30/08/2005 06/03/2006 inhibitors 11747, USA

Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 01/09/2005 Wef: 02/09/2004 Warrant signed on 2964 Chemical compounds Corporation Box 7929, Philadelphia, PA Vide PT 2964 Rec: 6077/8 dt 01/09/2005 Wef: 17/09/2004 16/03/2006 Att: SS & Co 19101, USA

Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 01/09/2005 Wef: 02/09/2004 Warrant signed on 2965 Chemical compounds Corporation Box 7929, Philadelphia, PA Vide PT 2965 Rec: 6080/1 dt 01/09/2005 Wef: 17/09/2004 16/03/2006 Att: SS & Co 19101, USA

Compostitions One Procter & Gamble The Procter & Gamble comprising 5-amino - 2- Plaza, Cinannati, Ohio Filing Date: 01/09/2005 Warrant signed on 2966 Company Wef: 01/09/2004 Vide PT 2966 hydroxybenzoic acid and 45202, United States of Rec: 6083/4 dt 01/09/2005 16/03/2006 Att: SS & Co a reducing sugar America

Processes for the Preparation of Celgene Corporation 86 Morris Avenue, Summit, Filing Date: 02/09/2005 Warrant signed on 2967 Substituted 2-(2,6- Wef :03/09/04 Vide PT 2967 Att: Mr John C. Lim NJ 07901, U.S.A. Rec: 6101/2 dt 05/09/2005 16/03/2006 Dioxopiperidin-3-YL)-1- Oxoisoindolines

Alkylidene- tetrahydronaphthalene derivatives, process for Schering AG Filing Date: 06/09/2005 Warrant signed on 2968 Berlin 13342, Germany Wef: 09/09/2004 Vide PT 2968 their production and Att: MAMO TCV Advocates Rec: 6153/4 dt 06/09/2005 16/03/2006 their use as anti- inflammatory agents Wef: 09/09/2005 Combinations of organic Novartis AG Lichtsrasse 35, 4056 Filing Date: 06/09/2005 Warrant signed on 2969 Wef: 14/09/2004 Vide PT 2969 compounds Att: SS & Co Basel, Switzerland Rec: 6164/5 dt 06/09/2005 16/03/2006 Wef: 10/06/2005

Glaxo Wellcome House, Novel cysteine protease Glaxo Group Limited Berkeley Avenue, Filing Date: 06/09/2005 Warrant signed on 2970 Wef: 07/09/2004 Vide PT 2970 inhibitors Att: SS & Co Greenford, Middlesex UB6 Rec: 6161/2 dt 06/09/2005 16/03/2006 0NN, Great Britain

Therapeutic diphenyl Pfizer Products Inc. Eastern Point Road, Filing Date: 06/09/2005 Wef: 10/09/2004 Warrant signed on 2971 Vide PT 2971 ether ligands Att: SS & Co Connecticut 06340, USA Rec: 6158/9 dt 06/09/2005 Wef: 14/07/2005 16/03/2006

Smithkline Beecham One Franklin Plaza, P.O Acyclic 1,3 - Diamines Filing Date: 06/09/2005 Warrant signed on 2972 Corporation Box 7929, Philadelphia, PA Wef: 07/09/2004 Vide PT 2972 and uses therefor Rec: 6156/7 dt 06/09/2005 16/03/2006 Att: SS & Co 19101, USA

Condensed pyrazole derivatives, their Sanofi-Aventis 174, Avenue de France, Filing Date: 07/09/2005 Warrant signed on 2973 preparation and Attn: S S & Co. Wef: 13/09/2004 Vide PT 2973 FR-75013 Paris, France Rec: 6192/3 dt 07/09/2005 16/03/2006 application in therapeutics

A nitrogen - containing ONO Pharmaceutical Co heterocyclic derivative 1-1 Sakurai 3- dome, Ltd Filing Date: 07/09/2005 Wef: 13/09/2004 Warrant signed on 2974 and a drug containing Shimamoto- cho, Miskima - Vide PT 2974 Attn: S S & Co. Rec: 6189/90 dt 07/09/2005 Wef: 26/04/2005 16/03/2006 the same as the active gun, Osaka, Japan ingredient

Process for IDNA Way, South San concentration of Genenteon Inc. & Novartis Francisco, California 94080- Filing Date: 07/09/2005 Warrant signed on 2975 antibodies and AG 4990, USA & Wef: 09/09/2004 Vide PT 2975 Rec: 6194/5 dt 07/09/2005 16/03/2006 therapeutic products Attt: Ganado & Associates Lichstrasse 35 Basel, CH- thereof 4056, Switzerland

Bicyclic amides as Novartis AG Lichtsrasse 35, 4056 Filing Date: 09/09/2005 Wef: 15/09/2004 Warrant signed on 2976 Vide PT 2976 kinase inhibitors Att: SS & Co Basel, Switzerland Rec: 6217/8 dt 09/09/2005 Wef: 08/06/2005 16/03/2006

6-9, Tliranomachi 2-chome, Mitsubishi Pharma Chuo-shi, Osaka-shi, 2- Morpholino - 4 - Corporation & Filing Date: 09/09/2005 Warrant signed on 2978 Osaka 541-0046, Japan & Wef: 09/09/2004 Vide PT 2978 pyrimidone compound Sanofi-Aveutis Rec: 6212/3 dt 09/09/2005 16/03/2006 174, Avenue de France, Att: SS & Co 75013 Paris, France

DIARYL-SUBSTITUTED Banyu Pharmaceutical Co. 2-3 Nihombashi-Honcho, 2- Filing Date: 09/09/2005 Warrant signed on 2980 HETERO 5 – MEMBERED Ltd chome, Chuo-Ku, Tokyo Wef: N/A Vide PT 2980 Rec: 6246/7 dt 13/09/2005 16/11/2007 RING DERIVATIVE Att: Dr M. Chetcuti Cauchi 103-8416, Japan Vanilloid receptor One Amgen Center Drive, Amgen Inc. Filing Date: 12/09/2005 Warrant signed on 2981 ligands and their use in Thousand Oaks, CA 91320 Wef: 13/09/2004 Vide PT 2981 Att: Dr M. Chetcuti Cauchi Rec: 6248/9 dt 13/09/2005 16/03/2006 treatments -1799, USA

Glaxo Smithkline Rue de L'Institut 89, B- Filing Date: 15/09/2005 Warrant signed on 2982 Vaccines Biologicals s.a. Wef: 16/09/2004 Vide PT 2982 1330 Rixensart, Belgium Rec: 6294/5 dt 15/09/2005 03/04/2006 Att: SS & Co

Shannon Airport House, Multiple sclerosis Vasogen Ireland Limited Filing Date: 15/09/2005 Warrant signed on 2983 Shannon, Country Clare, Wef: 15/09/2004 Vide PT 2983 Treatments Att: J. Mifsud Rec: 6307/8 dt 16/09/2005 16/03/2006 Ireland

Janssen Pharmaceutica Turnhoutseweg 30, B-2340 Novel pyridinone and N.V. & Addex Beerse, Belgium & Filing Date: 19/09/2005 their use as positive Warrant signed on 2984 Pharmaceuticals S.A 12, Chemin de Aulx 1228, Rec: P585531 dt Wef: 17/09/2004 Vide PT 2984 allosteric modulators of 03/04/2006 Att: Ellul Mifsud & Debono Plan-les-Ouates, (Geneva), 19/09/2005 MG LUR2-receptors Switzerland

Novel thieno - pyridine Janssen Pharmaceutica Turnhoutseweg 30, B-2340 and thieno - pyrimidine N.V. & Addex Beerse, Belgium & Filing Date: 19/09/2005 derivatives and their use Warrant signed on 2985 Pharmaceuticals S.A 12, Chemin de Aulx 1228, Rec: P585531 dt Wef: 17/09/2004 Vide PT 2985 as positive allosteric 03/04/2006 Att: Ellul Mifsud & Debono Plan-les-Ouates, (Geneva), 19/09/2005 modulators of MGLUR2- Switzerland receptors

(Arylamidoaryl) 58 South Service road, OSI Pharmaceuticals, Inc. Filing Date: 19/09/2005 Warrant signed on 2986 cyanoguanidine Suite 110, Melville, NY Wef: 17/09/2004 Vide PT 2986 Att: SS & Co Rec: 6381/2 dt 26/09/2005 03/04/2006 compounds 11747, USA

(Arylamidoanilino) 58 South Service road, OSI Pharmaceuticals, Inc. Filing Date: 19/09/2005 Warrant signed on 2987 nitraethylene Suite 110, Melville, NY Wef: 17/09/2004 Vide PT 2987 Att: SS & Co Rec: 6384/5 dt 26/09/2005 03/04/2006 compounds 11747, USA

58 South Service road, (Arylamidoaryl) OSI Pharmaceuticals, Inc. Filing Date: 19/09/2005 Warrant signed on 2988 Suite 110, Melville, NY Wef: 17/09/2004 Vide PT 2988 squaramide compounds Att: SS & Co Rec: 6387/8 dt 26/09/2005 03/04/2006 11747, USA

58 South Service road, (Hydrazido) (Amino) OSI Pharmaceuticals, Inc. Filing Date: 19/09/2005 Warrant signed on 2989 Suite 110, Melville, NY Wef: 17/09/2004 Vide PT 2989 thiophene compounds Att: SS & Co Rec: 6390/1 dt 26/09/2005 03/04/2006 11747, USA

(Spirocyclylamido) 58 South Service road, OSI Pharmaceuticals, Inc. Filing Date: 19/09/2005 Warrant signed on 2990 aminothiophene Suite 110, Melville, NY Wef: 17/09/2004 Vide PT 2990 Att: SS & Co Rec: 6393/4 dt 26/09/2005 03/04/2006 compounds 11747, USA

Eastern Point Road, Pfizer Products Inc. Filing Date: 20/09/2005 Warrant signed on 2992 Quinoline compounds Groton, Connecticut 06340, Wef: 23/09/2004 Vide PT 2992 Att: SS & Co Rec: 6336/7 dt 22/09/2005 05/04/2006 USA Compounds which One Franklin Plaza, PO Smithkline Beecham increase apolipiprotein A- Box 7929, Philadelphia, Filing Date: 20/09/2005 Warrant signed on 2993 Corporation Wef: 21/09/2004 Vide PT 2993 1 production and uses PA19101, United States of Rec: 6333/4 dt 22/09/2005 03/04/2006 Att: SS & Co therof in medicine America

4-amino substituted - 2 - Eastern Point Road, Wef: 23/09/2004 substituted - 1,2,3,4 - Pfizer Products Inc. Filing Date: 20/09/2005 Warrant signed on 2994 Groton, Connecticut 06340, Wef: 03/03/2005 Vide PT 2994 tetrahydroquinoline Att: SS & Co Rec: 6330/1 dt 22/09/2005 19/04/2006 USA Wef: 25/07/2005 compounds

Quinolizinone 2-1, Toranoman, 2-chome, Compound and use Japan Tabacco Inc. Filing Date: 20/09/2005 Wef: 21/09/2004 Warrant signed on 2995 Minato-Ku Vide PT 2995 thereof as HIV integrase Att: SS & Co Rec: 6327/8 dt 22/09/2005 Wef: 12/08/2005 03/04/2006 Tokyo 105-8422, Japan Inhibitor

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 20/09/2005 Wef: 21/09/2004 Warrant signed on 2996 Chemical compounds Vide PT 2996 Att: SS & Co Greenford, Middlesex, UB6 Rec: 6324/5 dt 22/09/2005 Wef: 30/06/2005 03/04/2006 0NN, Great Britian

Y2 SELECTIVE RECEPTOR AGONISTS 7 TM Pharma A/S Fremtidsvej 3, DK-2970 Filing Date: 20/09/2005 Warrant signed on 2997 Wef: N/A Vide PT 2997 FOR THERAPEUTIC Att: Dr M. Chetcuti Cauchi Hoersholm, Denmark Rec: 6318/9 dt 22/09/2005 16/11/2007 INTERVENTIONS

Substituted One Amgen Center Drive, Amgen Inc. Filing Date: 22/09/2005 Warrant signed on 2999 sulfonamidopropionami Thousand Oaks, CA Wef: 23/09/2004 Vide PT 2999 Att: Dr M. Chetcuti Cauchi Rec: 6365/6 dt 26/09/2000 03/04/2006 desand methods of use 91320-1799, USA

One Amgen Center Drive, Filing Date: 22/09/2005 Substituted heterocyclic Amgen Inc. Warrant signed on 3000 Thousand Oaks, CA Rec: 6368/9 dt 26/09/2005 Wef: 27/09/2004 Vide PT 3000 and methods of use Att: Dr M. Chetcuti Cauchi 03/04/2006 91320-1799, USA MT PT No Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract

Crystalline Clopidogrel 5 Basel Street, P.O. Box Teva Pharmaceutical Filing Date: 22/09/2005 hydrobromide and 3190, Petah Tiqva 49131, Wef: 04/10/2004 Warrant signed on 3001 Industries Ltd Rec: 6370/1 dt Vide PT 3001 processes for preparation Israel Wef: 21/09/2007 19/04/2006 Attn: Dr M Chetcuti Cauchi 26/09/2005 thereof

PO Box 4000, Route 206 Brtistol Myers Squibb Filing Date: 23/09/2005 C-aryl glucoside SGL T2 and Province Line Road, Warrant signed on 3002 Company Rec: 6356/7 dt Wef: 23/09/2004 Vidde PT 3002 inhibitors and method Princeton, New Jersey 03/04/2006 Att: Mamo TCV & Advocates 26/09/2005 08543-4000, USA

Filing Date: 23/09/2005 Inhibitors of soluble Schering AG Warrant signed on 3003 Berlin 13342, Germany Rec: 6359/60 dt Wef: 24/09/2004 Vide PT 3003 adenylate cyclase Att: MAMO TCV Advocates 03/04/2006 26/09/2005

Use of epothilones in the Filing Date: 23/09/2005 Schering AG Warrant signed on 3004 treatment of bone Berlin 13342, Germany Rec: 6362/3 dt Wef: 24/09/2004 Vide PT 3004 Att: MAMO TCV Advocates 03/04/2006 metastasis 26/09/2005

Filing Date: 23/09/2005 Wef: 24/09/2004 Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3005 Novel compounds Rec: 6449/50 of Wef: 24/09/2004 Vide PT 3005 Att: S S & Co Sweden 03/04/2006 27/09/2005 Wef: 30/12/2004

Filing Date: 23/09/2005 Wef: 24/09/2004 Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3006 Novel compounds Rec: 6446/7 dt Wef: 24/09/2004 Vide PT 3006 Att: S S & Co Sweden 03/04/2006 27/09/2005 Wef: 28/02/2005

Benzimidazole derivatives, Filing date 23/09/2005 Wef: 24/09/2004 compositions containing Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3007 Rec: 6443/4 dt Wef: 24/09/2004 Vide PT 3007 them, preparation thereof Att: S S & Co Sweden 03/04/2006 27/09/2005 Wef: 30/12/2004 and uses thereof

Compounds, compositions Filing Date: 23/09/2005 Wef: 24/09/2004 containing them, Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3008 Rec: 6440/1 dt Wef: 24/09/2004 Vide PT 3008 preparation thereof and Att: S S & Co Sweden 03/04/2006 27/09/2005 Wef: 24/01/2005 uses thereof

Compounds, compositions Filing Date: 23/09/2005 containing them, Astrazeneca AB SE 151 85 Sodertalje, Wef: 24/09/2004 Warrant signed on 3009 Rec: 6437/8 dt Vide PT 3009 preparation thereof and Att: S S & Co Sweden Wef: 31/12/2004 03/04/2006 27/09/2005 uses thereof Compounds, compositions Filing Date: 23/09/2005 containing them, Astrazeneca AB SE 151 85 Sodertalje, Wef: 24/09/2004 Warrant signed on 3010 Rec: 6434/5 dt Vide PT 3010 preparation thereof and Att: S S & Co Sweden Wef: 03/02/2005 03/04/2006 27/09/2005 uses thereof

Compounds, compositions Filing Date: 23/09/2005 containing them, Astrazeneca AB SE 151 85 Sodertalje, Wef: 24/09/2004 Warrant signed on 3011 Rec: 6430/1 dt Vide PT 3011 preparation thereof and Att: S S & Co Sweden Wef: 30/12/2004 03/04/2006 27/09/2005 uses thereof

Memantine for the treatment Merz Pharma GmbH & Co Eckenheimer Filing Date: 23/09/2005 Warrant signed on 3012 of childhood behaviour KGAA Landstrasse 100, D-60318 Rec: 6351/2 dt Wef: 23/09/2004 Vide PT 3012 03/04/2006 disorders Att: Dr M Chetcuti Cauchi Frankfurt, Germany 26/09/2005

One Amgen Centre Drive, Filing Date: 25/09/2005 Amgen Inc. Warrant signed on 3013 Modified FC molecules Thousand Oaks, CA 91320- Rec: 6426/7 dt Wef: 23/09/2004 Vide PT 3013 Att: Dr M Chetcuti Cauchi 03/04/2006 1799, USA 27/09/2005

PO Box 4000, Route 206 Crystalline and process for Brtistol Myers Squibb Filing Date: 27/09/2005 Wef: 01/10/2004 and Province Line Road, Warrant signed on 3014 preparing spiro-hydanton Company Rec: 6419/20 dt Wef: 12/10/2004 Vide PT 3014 Princeton, New Jersey 03/01/2008 compounds Att: MAMO TCV Advocates 27/09/2005 Wef: 15/09/2005 08543-4000, USA

Substituted 2- anilinopyrimidine as cell- Filing Date: 27/09/2005 cyde-kinase or receptor- Schering AG Wef: 29/09/2004 Warrant signed on 3015 Berlin 13342, Germany Rec: 6416/7 dt Vide PT 3015 tyrosine-kinase inhibitors, Att: MAMO TCV Advocates Wef: 06/10/2004 04/05/2006 27/09/2005 their production and use as pharmaceutical agents

PO Box 4000, Route 206 Brtistol Myers Squibb Filing Date: 27/09/2005 Crystalline forms of a factor and Province Line Road, Warrant signed on 3016 Company Rec: 6413/4 dt Wef: 28/09/2004 Vide PT 3016 XA inhibitor Princeton, New Jersey 03/04/2006 Att: MAMO TCV Advocates 27/09/2005 08543-4000, USA

PO Box 4000, Route 206 Brtistol Myers Squibb Filing Date: 27/09/2005 Prodrugs of protein tyrosine and Province Line Road, Warrant signed on 3017 Company Rec: 6410/1 dt Wef: 27/09/2004 Vide PT 3017 kinase inhibitors Princeton, New Jersey 03/04/2006 Att: MAMO TCV Advocates 27/09/2005 08543-4000, USA

6-9, Hiranomachi 2-Chome, Mitsubishi Pharma Chino-ku, Osaka 541 - Filing Date: 27/09/2005 Corporation & Sanofi - 0046, Japan & 174 Avenue Warrant signed on 3018 Pyrimidone compound Rec: 6406/7 dt Wef: 29/09/2004 Vide PT 3018 Aventis de France, FR - 75013 16/05/2006 27/09/2005 Att: S S & Co. Paris, France Clostridial neurotoxins Merz Pharma GmbH & Co Eckenheimer Landstrasse Filing Date: 27/09/2005 (natural and modified types) Warrant signed on 3019 KGAA 100, D-60318 Frankfurt, Rec: 6452/3 dt Wef: 27/09/2004 Vide PT 3019 with short biological 03/04/2006 Att: Dr M Chetcuti Cauchi Germany 27/09/2005 persistence

Fructuos Gelabert, 6-8 Filing Date: 28/09/2005 Process for preparing Medicham S.A. Warrant signed on 3020 08970 Sant Joan Despi, Rec: 6517/8 dt Wef: 29/09/2004 Vide PT 3020 ziprasidone Att: J Mifsud 03/04/2006 Barcelona, Spain 29/09/2005

Fructuos Gelabert, 6-8 Filing Date: 28/09/2005 Process for purification of Medicham S.A. Warrant signed on 3021 08970 Sant Joan Despi, Rec: 6514/5 dt Wef: 29/09/2004 Vide PT 3021 ziprasidone Att: J Mifsud 03/04/2006 Barcelona, Spain 29/09/2005

Fexofenadine crystal form Teva Pharmaceutical Filing Date: 28/09/2005 Basel Street, PO Box 3190 Warrant signed on 3022 and processes for its Industries Ltd Rec: 6511/2 dt Wef: 28/09/2004 Vide PT 3022 Petah Tiqva, 49131, Israel 03/04/2006 preparation thereof Att: Dr M Chetcuti Cauchi 29/09/2005

Process for preparing forms Teva Pharmaceutical Filing Date: 28/09/2005 of atorvastatin calcium Basel Street, PO Box 3190 Warrant signed on 3023 Industries Ltd Rec: 6508/9 of Wef: 28/09/2004 Vide PT 3023 substantially free of Petah Tiqva, 49131, Israel 03/04/2006 Att: Dr M Chetcuti Cauchi 29/09/2005 impurities

One Franklin Plaza, PO Smithkline Beecham Filing Date: 04/10/2005 Box 7929, Philadelphia, Wef: 05/10/2004 Warrant signed on 3025 Novel compounds Corporation Rec: 6655/6 dt Vide PT 3025 PA19101, United States of Wef: 22/09/2005 19/04/2006 Att: S S & Co. 04/10/2005 America

Raheems East , Filing Date: 04/10/2005 Recordati Ireland Limited Ringaskidoly Co Cork, Wef: 05/10/2004 Warrant signed on 3026 Lercanidipine capsules Rec: 6652/3 dt Vide PT 3026 Att: S S & Co Ireland Wef: 05/02/2005 19/04/2006 04/10/2005

Aryl nitrogen-containing One Amgen Centre Drive, Filing Date: 04/10/2005 Amgen Inc. Warrant signed on 3027 bicyclic compounds and Thousand Oaks, CA 91320 Rec: 6709/10 dt Wef: 01/10/2004 Vide PT 3027 Att: Dr Maria Chetcuti Cauchi 03/07/2006 methods of use - 1799, USA 06/10/2005

Ochsner Clinic Foundation Yong Sung CH01, 2229 Filing Date: 05/10/2005 Enhancement of B Cell Laboratory of Cellular Palmer Avenue, New Warrant signed on 3028 Rec: 6706/7 dt Wef: 05/10/2004 Vide PT 3028 proliferation by 1L-15 Immunology Orleans, Louisiana 70118, 04/05/2006 06/10/2005 ATT: MAMO TCV Advocates USA

Cyclic and acyclic Merz Pharma GmbH & Co Eckenheimer Filing Date: 05/10/2005 Wef: 05/10/2004 Warrant signed on 3029 propenones for treating KGAA Landstrasse 100, D-60318 Rec: 6703/4 dt Wef: 24/02/2005 Vide PT 3029 19/04/2006 CNS disorders Att: Dr M Chetcuti Cauchi Frankfurt, Germany 06/10/2005 Wef: 11/08/2005 Filing Date: 06/10/2005 Syngenta Participations AG Schwarzwaldallee 215, Warrant signed on 3030 Fungicidal compositions Rec: 6752/3 dt Wef: 08/10/2004 Vide PT 3030 Att: Dr M Chetcuti Cauchi 4058 Basel, Switzerland 19/04/2006 07/10/2005

Filing Date: 06/10/2005 Syngenta Participations AG Schwarzwaldallee 215, Warrant signed on 3031 Fungicidal compositions Rec: 6749/50 dt Wef: 08/10/2004 Vide PT 3031 Att: Dr M Chetcuti Cauchi 4058 Basel, Switzerland 04/05/2006 07/10/2005

One Amgen Centre Drive, Filing Date: 06/10/2005 Substituted sulfones and Amgen Inc. Warrant signed on 3032 Thousand Oaks, CA 91320 Rec: 6745/6 dt Wef: 06/10/2004 Vide PT 3032 methods of use Att: Dr Maria Chetcuti Cauchi 19/04/2006 - 1799, USA 07/10/2005

Filing Date: 10/10/2005 ON-Resin peptide cylisation Lonza AG Muchensteinstrasse 38, Wef: 19/10/2004 Warrant signed on 3035 Rec: 6804/5 dt Vide PT 3035 II Att: Dr M Chetcuti Cauchi 4002 Basel, Switzerland Wef: 25/04/2005 04/05/2006 10/10/2005

Filing Date: 11/10/2005 Heteroatoms - containing Novartis AG Lichstrasse 35, 4056 Basel, Wef: 12/10/2004 Warrant signed on 3036 Rec: 6825/6 dt Vide PT 3036 tricyclic compounds Att: S S & Co Switzerland Wef: 16/12/2004 19/04/2006 11/10/2005

Taste-making Filing Date: 11/10/2005 Sandoz AG Lichstrasse 35, 4056 Basel, Warrant signed on 3037 pharmaceutical Rec: 6827/8 dt Wef: 12/10/2004 Vide PT 3037 Att: S S & Co Switzerland 19/04/2006 compositions 11/10/2005

Lichstrasse 35, 4056 Basel, Novartis AG & Nordic Filing Date: 11/10/2005 Switzerland & Herlev Warrant signed on 3038 Use of organic compounds Bioscience AS Rec: 6830/1 dt Wef: 12/10/2004 Vide PT 3038 Hovegade 207, DK-2730 19/04/2006 Att: SS & Co. 11/10/2005 Herlev, Denmark

One Amgen Centre Drive, Filing Date: 12/10/2005 Novel B1 Bradykinin Amgen Inc. Warrant signed on 3039 Thousand Oaks, CA 91320 Rec: 6847/8 dt Wef: 12/10/2004 Vide PT 3039 receptor antagonists Att: Dr Maria Chetcuti Cauchi 19/04/2006 - 1799, USA 12/10/2005

Method of treating One Amgen Centre Drive, parkinson's disease in Amgen Inc. & University of Thousand Oaks, CA 91320 humans by convection- Filing Date: 13/10/2005 Kentucky Research - 1799, USA & Warrant signed on 3040 enhanced infusion of glial Rec: 6869/70 dt Wef: 13/10/2004 Vide PT 3040 Foundation 317 Whitney-Hendrickson, 19/04/2006 cell-line derived 13/10/2005 Att: J Mifsud Facility 0098 Lexington, neurotiopine factor to the Kentucky 40536, USA putamen Glaxo Wellcome House, Filing Date: 13/10/2005 Glaxo Group Limited Berkeley Avenue, Wef: 15/10/2004 Warrant signed on 3041 Novel compounds Rec: 6874/75 dt Vide PT 3041 Att: S S & Co Greenford, Middlesex UB6 Wef: 26/04/2005 19/04/2006 13/10/2005 0XN, Great Britain

Filing Date: 13/10/2005 Wef: 15/10/2004 Substituted adenines and Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3042 Rec: 6877/8 dt Wef: 18/03/2005 Vide PT 3042 the uses thereof Att: S S & Co Sweden 19/04/2006 13/10/2005 Wef: 15/07/2005

One Amgen Centre Drive, Filing Date: 13/10/2005 Triazoles and methods of Amgen Inc. Warrant signed on 3043 Thousand Oaks, CA 91320 Rec: 6891/2 dt Wef: 13/10/2004 Vide PT 3043 use Att: Dr Maria Chetcuti Cauchi 19/04/2006 - 1799, USA 13/10/2005

IDENTIFICATION AND Berlin 13342, Germany & CHARACTERIZATION OF Schering AG & Mophosys Lena-Christ-Stark 48, Filing Date: 13/10/2005 Warrant signed on 3044 FUNCTION-BLOCKING ANTI-AG Mastinsreid, Germany Rec: 6897/8 dt Wef: 14/10/2004 Vide PT 3044 19/04/2006 ED-B-FIBRONECTION Att: MAMO TCV Advocates 82152 13/10/2005 ANTIBODIES

Process for the Preparation of N-(3,5-Dichloropyrid-4-yl)- Glenmark Pharmaceuticals Swisscom Building, Filing Date: 13/10/2005 Wef: 14/10/2004 4-Difluoromethoxy-8- Warrant signed on 3045 S.A. Maladiere 23, Neuchâtel Rec: 6894/5 dt Wef: 13/10/2004 Vide PT 3045 Methanesulfonamido- 19/04/2006 Att: Mamo TCV 2000, Switzerland 13/10/2005 Wef: 21/10/2004 Dibenzo[B,D]Furan-1- Carboxamide

Teva Pharmaceuticals 5 Basel Street, P.O. Box Filing Date: 13/10/2005 Process for Preparing Warrant signed on 3046 Industries Ltd 3190, Petah Tiqva 49131, Rec: 6942/3 dt Wef: 15/10/2004 Vide PT 3046 Telmisartan 19/04/2006 Att: CC Advocates Israel 14/10/2005

One Amgen Centre Drive, Filing Date: 14/10/2005 Vanilloid receptor ligands Amgen Inc Warrant signed on 3047 Thousand Oaks, CA 91320 Rec: 6945/6 dt Wef: 15/10/2004 Vide PT 3047 and their use in treatments Att: Dr Maria Chetcuti Cauchi 19/04/2006 - 1799, USA 14/10/2005

Filing Date: 18/10/2005 Novartis AG Lichtstrasse 35, 4056 Wef: 22/10/2004 Warrant signed on 3048 Organic compounds Rec: 7003/4 dt Vide PT 3048 Att: S S & Co Basel, Switzerland Wef: 15/07/2005 04/05/2006 19/10/2005

Compounds and Filing Date: 18/10/2005 compositions as inhibitors TRM LLC Hurstholme 12, Trott Road, Wef: 26/10/2004 Warrant signed on 3049 Rec: 7000/1 dt Vide PT 3049 of cannabinoid receptor 1 Att: S S & Co. Hamilton, Bermuda HM 11 Wef: 18/04/2005 04/05/2006 19/10/2005 activity 436 Cambridge Science Astex Therapeutics Limited Park, Milton Road, & Cancer Research Cambridge, CB4 0QA, Technology Limited & The United Kingdom & Sardinia Filing Date: 18/10/2005 Wef: 25/10/2004 Warrant signed on 3050 Pharmaceutical compounds Institure of Cancer House, Sardinia Street, Rec: 6997/8 dt Wef: 25/10/2004 Vide PT 3050 04/05/2006 Research : Royal Cancer London WC2A 3NL & 123 19/10/2005 Wef: 24/05/2005 Hospital Old Brompton Road, Att: S S & Co London SW7 3RP, United Kingdom

436 Cambridge Science Astex Therapeutics Limited Park, Milton Road, & Cancer Research Cambridge, CB4 0QA, Technology Limited & The United Kingdom & Sardinia Filing Date: 18/10/2005 Wef: 25/10/2004 Warrant signed on 3051 Pharmaceutical compounds Institure of Cancer House, Sardinia Street, Rec: 6994/5 dt Wef: 25/10/2004 Vide PT 3051 04/05/2006 Research : Royal Cancer London WC2A 3NL & 123 19/10/2005 Wef: 24/05/2005 Hospital Old Brompton Road, Att: S S & Co London SW7 3RP, United Kingdom

BBV Tower, 8th Floor , 254 Munoz Riviera Avenue, CRF Receptor antagonists SB Pharmco Puerto Rico Filing Date: 18/10/2005 San Juan, Puerto Rico Wef: 19/10/2004 Warrant signed on 3052 and methods relating Inc. & Neurocrine Rec: 6991/2 dt Vide PT 3052 00918, United States & Wef: 30/09/2005 04/05/2006 thereto Biosciences Inc 19/10/2005 12790 EL Camino Real, San Diego CA 92130, USA

Processes for Preparing Teva Pharmaceutical 5 Basel Street, P.O. Box Filing Date: 18/10/2005 Warrant signed on 3053 Amorphous Atorvastatin Industries Ltd 3190, Petah Tiqva 49131, Rec: 6987/8 dt Wef: 18/10/2004 Vide PT 3053 04/05/2006 Hemi-Calcium Att: CC Advocates Israel 19/10/2005

Heteroaryl-substituted One Amgen Centre Drive, Filing Date: 18/10/2005 Amgen Inc. Wef: 18/10/2004 Warrant signed on 3054 alkyne compounds and Thousand Oaks, CA 91320 Rec: 6984/5 dt Vide PT 3054 Att: Dr Maria Chetcuti Cauchi Wef: 14/10/2005 19/06/2006 method of use - 1799, USA 19/10/2005

Wef: 18/10/2004 2-1, Toranomon 2-chome, Filing Date: 18/10/2005 Ester derivatives and Japan Tobacco Inc. Wef: 25/02/2005 Warrant signed on 3055 Minato - ku, Tokyo 105- Rec: 6978/9 dt Vide PT 3055 medicinal use thereof Att: Bezzina & Mifsud Wef: 25/10/2004 16/05/2006 8422, Japan 19/10/2005 Wef: 04/03/2005

One Amgen Centre Drive, Filing Date: 18/10/2005 Thiadiazole compounds and Amgen Inc. Warrant signed on 3056 Thousand Oaks, California Rec: 6981/2 dt Wef: 18/10/2004 Vide PT 3056 methods of use Att: Bezzina & Mifsud 18/10/2005 91320 - 1799, USA 19/10/2005 One Amgen Centre Drive, Filing Date: 19/10/2005 Angiopoietin -2- specific Amgen Inc. Wef: 19/10/2004 Warrant signed on 3057 Thousand Oaks, California Rec: 7021/2 dt Vide PT 3057 binding agents Att: Bezzina & Mifsud Wef: 04/11/2004 04/05/2006 91320 - 1799, USA 20/10/2005

Istituto Di Ricerche Di Tetracyclic indole Via Pontina Via 1, 30600, I- Filing Date: 20/10/2005 Biologia Molecolare P Wef: 26/10/2004 Warrant signed on 3058 derivatives as antiviral 00040 Pomezia, Rome, Rec: 7038/9 dt Vide PT 3058 Angeletti SPA Wef: 21/06/2005 04/05/2006 agents Italy 20/10/2005 Att: Dr M Chetcuti Cauchi

Filing Date: 20/10/2005 Wef: 22/10/2004 Janssen Pharmaceutica NV Turnhoutseweg 30, B-2340 Warrant signed on 3059 Inhibitors of C-FMS kinase Rec: 7050/1 dt Wef: 11/04/2005 Vide PT 3059 Att: EMD Advocates Beerse, Belgium 04/05/2006 21/10/2005 Wef: 20/10/2005

One Amgen Centre Drive, Filing Date: 20/10/2005 Immunex Corporation Warrant signed on 3060 Tweak Receptor Thousand Oaks, California Rec: 7066/7 dt Wef: 22/10/2004 Vide PT 3060 Att: Dr M Chetcuti Cauchi 04/05/2006 91320 - 1799, USA 21/10/2005

One Amgen Centre Drive, Filing Date: 21/10/2005 Vanilloid receptor ligands Amgen Inc Warrant signed on 3061 Thousand Oaks, California Rec: 7069/70 dt Wef: 22/10/2004 Vide PT 3061 and their use in treatments Att: Dr Maria Chetcuti Cauchi 04/05/2006 91320 - 1799, USA 21/10/2005

One Amgen Centre Drive, Filing Date: 21/10/2005 Methods for Refolding of Amgen Inc. Wef: 22/10/2004 Warrant signed on 3062 Thousand Oaks, California Rec: 7071/2 dt Vide PT 3062 Recombinant Antibodies Att: B&M Patentbureau Wef: 22/07/2005 04/05/2006 91320 - 1799, USA 21/10/2005

Method and Media for One Amgen Centre Drive, Filing Date: 21/10/2005 Amgen Inc Warrant signed on 3063 Single Cell Serum-Free Thousand Oaks, California Rec: 7079/80 dt Wef: 22/10/2004 Vide PT 3063 Att: MAMO TCV Advocates 04/05/2006 Culture of CHO Cells 91320 - 1799, USA 21/10/2005

GlaxoSmithKline Filing Date: 25/10/2005 rue de l'Institut 89, B-1330 Wef: 27/10/2004 Warrant signed on 3064 Novel Process Biologicals s.a. Rec: 7133/4 dt Vide PT 3064 Rixensart, Belgium Wef: 26/01/2005 04/05/2006 Att: SS & Co. 26/10/2005

Glaxo Wellcome House, Filing Date: 25/10/2005 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3065 Compounds Rec: 7136/7 dt Wef: 25/10/2004 Vide PT 3065 Att: S S & Co. Greenford , Middlesex UB6 04/05/2006 26/10/2005 0XN, Great Britain

Filing Date: 25/10/2005 Astrazeneca AB SE 151 85 Sodertalje, Wef: 29/10/2004 Warrant signed on 3066 Chemical compounds Rec: 7139/40 dt Vide PT 3066 Att: S S & Co Sweden Wef: 22/03/2005 04/05/2006 26/10/2005 Solid formulation with improved solubility and 2-1, Toranomon 2-chome, Filing Date: 25/10/2005 Japan Tobacco Inc Wef: 25/10/2004 Warrant signed on 3067 stability and method for Minato - ku, Tokyo 105- Rec: 7142/3 dt Vide PT 3067 Att: S S & Co Wef: 30/11/2004 04/05/2006 producing said 8422, Japan 26/10/2005 formulations

Poligons Industrial La Mina, Pharma Mar SA Sociedad Filing Date: 25/10/2005 Arda de los Rayesl, Warrant signed on 3068 Formulations Unipersonal Rec: 7145/6 dt Wef: 29/10/2004 Vide PT 3068 Colmenar Viejo, E-28770 04/05/2006 Att: S S & Co 26/10/2005 Madrid, Spain

Filing Date: 25/10/2005 Sulfonyl benzimidazole Pfizer Inc 235 East End 42nd Street, Wef: 02/11/2004 Warrant signed on 3069 Rec: 7149/50 dt Vide PT 3069 derivatives Att: S S & Co New York 10017, USA Wef: 30/06/2005 16/05/2006 26/10/2005

Filing Date: 25/10/2005 Astrazeneca AB SE-15185, Sodertalje, Warrant signed on 3070 Chemical compounds Rec: 7151/2 dt Wef: 29/10/2004 Vide PT 3070 Att: S S & Co Sweden 04/05/2006 26/10/2005

Filing Date: 25/10/2005 Novartis AG Lichstrasse 35, 4056 Basel, Warrant signed on 3071 Organic compounds Rec: 7154/5 dt Wef: N/A Vide PT 3071 Att: S S & Co Switzerland 23/11/2007 26/10/2005

Novel aminopyridine 1-13-12, Kudankita, Filing Date: 25/10/2005 Banyu Pharmaceuticals Wef: 29/10/2004 Warrant signed on 3072 derivatives having aurora a Chiyoda-ku, Tokyo Rec: 7114/5 dt Vide PT 3072 Att: Dr M Chetcuti Cauchi Wef: 01/06/2005 16/05/2006 selective inhibitory action 1028667, Japan 25/10/2005

58 South Service Road, Filing Date: 26/10/2005 (2-Carboxamido) (3-amino) OSI Pharmaceuticals Inc. Warrant signed on 3073 Suite 110, Melville, Rec: 7130/1 dt Wef: 26/10/2004 Vide PT 3073 thiophene compounds Att: S S & Co 04/05/2006 NY11747, USA 26/10/2005

S-alkyl-sulphenyl protection Filing Date: 26/10/2005 Lonza AG Münchensteinerstrasse 38, Warrant signed on 3074 groups in solid-phase Rec: 7163/4 dt Wef: 26/10/04 Vide PT 3074 Att: CC Advocates 4002 Basel, Switzerland 04/05/2006 synthesis 26/10/2005

Filing Date: 28/10/2005 Estrogen receptor Merck & Co Inc. 126 East Lincoln Avenue, Warrant signed on 3075 Rec: 72256 dt Wef: 01/11/2004 Vide PT 3075 modulators Att: Dr M Chetcuti Cauchi Rahway, NJ07065, USA 16/05/2006 28/10/2005

Filing Date: 31/10/2005 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3076 Organic compounds Rec: 7259/60 dt Wef: 02/11/2004 Vide PT 3076 Att: S S & Co Basel, Switzerland 16/05/2006 02/11/2005 Filing Date: 31/10/2005 Novartis AG Lichtstrasse 35, 4056 Wef: 05/11/2004 Warrant signed on 3077 Organic compounds Rec: 7262/3 dt Vide PT 3077 Att: S S & Co Basel, Switzerland Wef: 07/01/2005 16/05/2006 02/11/2005

Filing Date: 01/11/2005 Composition of organic Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3078 Rec: 7278/9 dt Wef: 05/11/2004 Vide PT 3078 compounds Att: S S & Co Basel, Switzerland 16/05/2006 21/11/2005

New Benzothiadiazine compounds, a process for 12, Place de la Defence, Filing Date: 01/11/2005 their preparation and Les Laboratoires Servier Warrant signed on 3079 92415 Courbevoie Cedex, Rec: 7281/2 dt Wef: 03/11/2004 Vide PT 3079 pharmaceutical Att: S S & Co 16/05/2006 France 02/11/2005 compositions containing them.

New Benzothiadiazine compounds, a process for 12, Place de la Defence, Filing Date: 01/11/2005 their R preparation and Les Laboratoires Servier Warrant signed on 3080 92415 Courbevoie Cedex, Rec: 7284/5 dt Wef: 03/11/2004 Vide PT 3080 pharmaceutical Att: S S & Co 16/05/2006 France 02/11/2005 compositions containing them.

Novel anthranilamide pyridinureas as vascular Filing Date: 01/11/2005 Schering AG Warrant signed on 3081 endothelial growth factor Berlin 13342, Germany Rec: 7265/6 dt Wef: 03/11/2004 Vide PT 3081 Att: Mamo TCV Advocates 16/05/2006 (VEGF) receptor kinase 02/11/2005 inhibitors

Oral solid dosage forms Filing Date: 01/11/2005 Schering AG Warrant signed on 3082 containing a low dose of Berlin 13342, Germany Rec: 7268/9 dt Wef: 02/11/2004 Vide PT 3082 Att: Mamo TCV Advocates 16/05/2006 estradiol 21/11/2005

PO Box 4000, Route 206 Contrained compounds as Brtistol Myers Squibb Filing Date: 01/11/2005 Wef: 03/11/2004 and Province Line Road, Warrant signed on 3083 CGRP-Receptor Company Rec: 7273/4 of Wef: 05/05/2005 Vide PT 3083 Princeton, New Jersey 30/05/2006 Antagonists Att: MAMO TCV Advocates 02/11/2005 Wef: 11/10/2005 08543-4000, USA

Combination of a SRC PO Box 4000, Route 206 Wef: 04/11/2004 kinase inhibitor and a BCR- Brtistol Myers Squibb Filing Date: 01/11/2005 and Province Line Road, Wef: 01/12/2004 Warrant signed on 3084 ABL inhibitor for the Company Rec: 7271/2 of Vide PT 3084 Princeton, New Jersey Wef: 03/02/2005 16/05/2006 treatment of proliferative Att: MAMO TCV Advocates 05/11/2005 08543-4000, USA Wef: 29/07/2005 diseases

Filing Date: 01/11/2005 Lonza AG Munchensteinerstrasse 38, Wef: 01/11/2004 Warrant signed on 3085 Cyclization of a peptide Rec: 7276/7 dt Vide PT 3085 Att: Dr M Chetcuti Cauchi 4002 Basel, Switzerland Wef: 18/04/2005 16/05/2006 02/11/2005 Tadalafil crystal forms and Teva Pharmaceutical S Basel Street, PO Box Filing Date: 02/11/2005 Wef: 02/11/2004 Warrant signed on 3086 processes for preparing Industries Ltd 3190 Petah Tiqva 49131, Rec: 7309/10 dt Vide PT 3086 Wef: 07/01/2005 16/05/2006 them Att: Dr M Chetcuti Cauchi Israel 03/11/2005

Filing Date: 03/11/2005 New modified release pellet Astazeneca AB SE 151 85 Sodertalje, Rec: 7315/6 dt Warrant signed on 3087 formulations for proton Wef: 04/11/2004 Vide PT 3087 Att: S S & Co Sweden 03/11/2005 16/05/2006 pump inhibitors

New modified release tablet Filing Date: 03/11/2005 Astrazeneca AB SE 151 85 Sodertalje, Warrant signed on 3088 formulations for proton Rec: 7318/9 dt Wef: 04/11/2004 Vide PT 3088 Att: S S & Co Sweden 16/05/2006 pump inhibitors 03/11/2005

Amorphous and Teva Pharmaceutical 5 Basel Street, PO Box Filing Date: 03/11/2005 Wef: 03/11/2004 Warrant signed on 3089 polymorphic forms of Industries Ltd 3190 Petah Tiqva 49131, Rec: 7341/2 dt Vide PT 3089 Wef: 11/02/2005 16/05/2006 telmisartan sodium Att: Dr M Chetcuti Cauchi Israel 04/11/2005

L-tartrate salt of N-1- adamantyl -2- (3-[(2R) -2 Filing Date: 04/11/2005 ({(2R) -2- hydroxy -2-(4- Pfizer Inc. 235 East 42nd Street, New Warrant signed on 3090 Rec: 7378/9 dt Wef: 12/11/2004 Vide PT 3090 hydroxy -3- (hydroxymethyl) Att: S S & Co. York 10017, USA 16/05/2006 04/10/2005 phenyl] ethyl amino) propyl] phenyl } ace tamide

436 Cambridge Science Astex Therapeutics Limited Park, Milton Road, & Cancer Research Cambridge, CB4 0QA, Technology Limited & The United Kingdom & Sardinia Filing Date: 04/11/2005 Wef: 09/11/2004 Warrant signed on 3091 Pharmaceutical compounds Institure of Cancer House, Sardinia Street, Rec: 7375/6 dt Vide PT 3091 Wef: 09/11/2004 16/05/2006 Research : Royal Cancer London WC2A 3NL & 123 04/11/2005 Hospital Old Brompton Road, Att: S S & Co London SW7 3RP, United Kingdom

Filing Date: 04/11/2005 Astazeneca AB SE 151 85 Sodertalje, Warrant signed on 3092 Novel compounds Rec: 7372/3 dt Wef: 09/11/2004 Vide PT 3092 Att: S S & Co Sweden 16/05/2006 04/11/2005

Compounds and Filing Date: 04/11/2005 IRM LLC Hurstholme 12, Trott Road, Wef: 09/11/2004 Warrant signed on 3093 compositions as protein Rec: 7369/70 dt Vide PT 3093 Att: S S & Co Hamilton, Bermuda HM 11 Wef: 19/11/2005 16/05/2006 kinase inhibitors 04/11/2005 Composition and method Filing Date: 07/11/2005 Arrow International Limited 57 St Christopher Street, Wef: 10/11/2004 Warrant signed on 3094 for treatment of alopecia Rec: 7421/2 dt Vide PT 3094 Att: S S & Co Valletta VLT 08, Malta Wef: 19/07/2005 19/06/2006 areata 09/11/2005

Substituted N- Filing Date: 08/11/2005 Wef: 10/11/2004 Sulfonylaminobenzyl -2- Pfizer Inc. 235 East 42nd Street, New Warrant signed on 3095 Rec: 7428/9 dt Wef: 10/03/2005 Vide PT 3095 phenoxyacetamide Att: S S & Co York 10017, USA 16/05/2006 09/11/2005 Wef: 15/07/2005 compounds

1,4 substituted Filing Date: 08/11/2005 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3096 pyrazolopyrimidines as Rec: 7425/6 dt Wef: 12/11/2004 Vide PT 3096 Att: S S & Co Basel, Switzerland 16/05/2006 kinase inhibitors 09/11/2005

5- Substituierte chinolin - und isochinolin derivative, Filing Date: 09/11/2005 ein verfahren zu ihrer Schering AG Wef: 12/11/2004 Warrant signed on 3097 Berlin 13342, Germany Rec: 7462/3 dt Vide PT 3097 herstellung und ihre Att: Mamo TCV Advocates Wef: 26/04/2005 16/05/2006 09/11/2005 verwendung als entzudungshemmer

Glaxo Wellcome House, Berkelay Avenue, Greenford , Middlesex UB6 Filing Date: 10/11/2005 Macrolones - amino Glaxo Group Limited & Pliva Warrant signed on 3098 0NN, Great Britain & Rec: 7486/7 dt Wef: 11/11/2004 Vide PT 3098 substituted quinolines Att: S S & Co 16/05/2006 Istrazivaeki Institut d.o.o 10/11/2005 Prilaz Waruna, Filipovina 29, 10000 Zajreb, Croatia

Eastern Point Road, Filing Date: 11/11/2005 Azabenzoxazoles for the Pfizer Products Inc. Warrant signed on 3099 Groton, Connecticut 06340, Rec: 7511/2 dt Wef: 15/11/2004 Vide PT 3099 treatment of CNS disorders Att: S S & Co. 16/05/2006 USA 11/11/2005 MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No

Eastern Point Road, Filing Date: 11/11/2005 Azabenzoxazoles for the Pfizer Products Inc. Warrant signed on 3100 Groton, Connecticut Rec: 7514/5 dt Wef: 15/11/2004 Vide PT 3100 treatment of CNS disorders Att: SS & Co. 10/05/2006 06340, USA 11/11/2005

58, South Service Road, Filing Date: 11/112005 Integrin antogonists useful OSI Pharmaceuticals Inc. Warrant signed on 3101 Suite 110, Melville, NY Rec: 7517/8 dt Wef: 12/11/2004 Vide PT 3101 as anti cancer agents Att: SS & Co. 16/05/2006 11747, USA 11/11/2005

Filing Date: 15/11/2005 Novartis AG Lichstrasse 35, 4056 Warrant signed on 3102 Organic compounds Rec: 7534/5 dt Wef: 19/11/2004 Vide PT 3102 Att: SS & Co Basel, Switzerland 30/05/2006 15/11/2005

Warner-Lambert Company 201, Tabor Road, Morris Filing Date: 15/11/2005 Novel pyrazole-based HMG Warrant signed on 3103 LLC Plains, New Jersey Rec: 7537/8 dt Wef: 23/11/2005 Vide PT 3103 GoA reductase Inhibitors 30/05/2006 Att: SS &Co 07950, USA 15/11/2005

Filing Date: 15/11/2005 Octahydropyrrolo [3,4-c] Pfizer Inc. 235 East 42nd Street, Wef: 24/11/2004 Warrant signed on 3104 Rec: 7540/1 dt Vide PT 3104 pyrrole Att: SS & Co New York 10017, USA Wef: 26/11/2005 30/05/2006 15/11/2005

Filing Date: 15/11/2005 Pfizer Inc. 235 East 42nd Street, Warrant signed on 3105 Novel compounds Rec: 7543/4 dt Wef: 23/11/2004 Vide PT 3105 Att: SS & Co New York 10017, USA 30/05/2006 15/11/2005

Eastern Point Road, Filing Date: 15/11/2005 Dibenzyl Amine Compounds Pfizer Products Inc. Wef: 23/11/2004 Warrant signed on 3106 Groton, Connecticut Rec: 7546/7 dt Vide PT 3106 and Derivatives Att: SS & Co Wef: 12/09/2005 30/05/2006 06340, USA 15/11/2005

3- pheuyl- pyrazole Wef: 19/11/2004 derivatives as modulators of Arena Pharmaceuticals 6166 Nancy Ridge Drive Filing Date: 16/11/2005 Wef: 26/01/2005 the - 5 HT2A serotonin Warrant signed on 3107 Inc. , San Diego, California Rec: 7581/2 dt Wef: 02/03/2005 Vide PT 3107 receptor useful for the 30/05/2006 Att: Dr M. Chetcuti Cauchi 92121, USA 16/11/2005 Wef: 01/09/2005 treatment of disorders Wef: 04/11/2005 related thereto

Enteric coated bead PO Box 206 and Bristol-Myers Squibb Filing Date: 17/11/2005 comprising ixabepilone and Province Line Road, Warrant signed on 3108 Company Rec: 7600 /1 dt Wef: 18/11/2004 Vide PT 3108 preparation and Princeton, New Jersey 30/05/2006 Att: MAMO TCV Advocates 17/22/2005 administration thereof 08543-4000, USA

Filing Date: 18/11/2005 SmithKline Beecham One Franklion Plaza, PO Rec: 7636/7 dt Warrant signed on 3109 Novel compositions Corporation Box 7929, Philadelpia Wef: 18/11/2004 Vide PT 3109 18/11/2005 30/05/2006 Att: SS & Co. PA 19101, USA Novel compounds that modulate ppary Type Galderma Research & 635, Route des Lucioles, Filing Date: 18/11/2005 Warrant signed on 3110 receptors, and use therof in Development, S.N.C BP87 06902 Sophia Rec: 7633/4 dt Wef: 19/11/2004 Vide PT 3110 30/05/2006 cosmetic or pharmaceutical Att: SS & Co Antipolis Cedex, France 18/11/2005 compositions

5- Nitro- neucleoside Genelabs Technologies 505, Panobscot Drive, Filing Date: 18/11/2005 Warrant signed on 3111 Compounds for treating viral Inc. Redwood City, California Rec: 7630/1 dt Wef: 22/11/2004 Vide PT 3111 30/05/2006 infections Att: SS & Co 94063, USA 18/11/2005

16711 Trans-Canada Filing Date: 18/11/2005 Cathepsin cysteine Protease Merck Frosst Canada Ltd Highway, Kirkland, Warrant signed on 3112 Rec: 7647/8 dt Wef: 23/11/2004 Vide PT 3112 inhibitors Att: Dr M. Chetcuti Cauchi Quebec H9H 3H, 30/05/2006 21/11/2005 Canada

Warner-Lambert Company 201, Tabor Road, Morris Filing Date: 22/11/2005 Therapeutic pyrazolo [3,4-b] Warrant signed on 3113 LLC Plains, New Jersey Rec: 7714/5 dt Wef: 29/11/2004 Vide PT 3113 pyridines and indazoles? 30/05/2006 Att: SS &Co 07950, USA 23/11/2005

Filing Date: 22/11/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 23/11/2004 Warrant signed on 3114 Novel compounds Rec: 7717/8 dt Vide PT 3114 Att: SS & Co. Sweden Wef: 30/04/2005 30/05/2006 23/11/2005

Crystalline forms of 3'-tert- PO Box 4000, Route 206 Bytul - 3'- N-tert - Bristol-Myers Squibb Filing Date: 23/11/2005 and Province Line Road, Warrant signed on 3115 butyloxycarbonyl - 4 deacetyl Company Rec: 7721/2 dt Wef: 23/11/2004 Vide PT 3115 Princeton, New Jersey 30/05/2006 - 3'- debenzoyl- 4 -0- Att: MAMO TCV Advocates 23/11/2005 08543-4000, USA methoxycarbonyl - paclitaxel

Filing Date: 24/11/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3116 Novel compounds Rec: 7797/8 dt Wef: 30/11/2004 Vide PT 3116 Att: SS & Co Sweden 30/05/2006 28/11/2005

Nitogen - containing fused 21, Toranomon 2- Filing Date: 24/11/2005 Japan Tabacco Inc. Wef: 29/11/2004 Warrant signed on 3117 ring compounds and use chome, Minato-Ku, Rec: 7800/1 dt Vide PT 3117 Att: SS & Co Wef: 07/12/2004 30/05/2006 therof Tokyo 105-8422, Japan 28/11/2005

Process for preparing novel crystalline forms of (2S) - 1 - II (7R) - 3), 4- dichlorophenyl) - 4,7 - dihydro - 5- PO Box 4000, Route 206 Bristol-Myers Squibb Filing Date: 24/11/2005 methylpyrazolo [1,5] and Province Line Road, Warrant signed on 3118 Company Rec: 7762/3 dt Wef: 24/11/2004 Vide PT 3118 pyrimidine - 6 YL] carbonyl] - Princeton, New Jersey 30/05/2006 Att: MAMO TCV Advocates 24/11/2005 2- (4-flourophenyl) 08543-4000, USA pyrrolidine, novel stable forms produced therein and formulations New Process for the Fructuós Gelabert, 6-8, Medichem S.A. Filing Date 28/11/2005 Warrant signed on 3120 preparation of a leukotriene E-08970 Sant Joan Wef: 30/11/04 Vide PT 3120 Att: B&M Patentbureau Rec 7805/6 dt 29/11/2005 30/05/2006 antagonist Despí, Barcelona, Spain

Filing Date: 29/11/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 06/12/2004 Warrant signed on 3121 Novel Compounds Rec: 7814/5 dt Vide PT 3121 Att: SS & Co Sweden Wef: 13/05/2005 19/06/2006 29/11/2005

Combinations comprising epothilones and protein Filing Date: 29/11/2005 Novartis AG Lichstrasse 35, 4056 Warrant signed on 3122 tyrosine kinase inhibitors Rec: 7817/8 dt Wef: 30/11/2004 Vide PT 3122 Att: SS & Co Basel, Switzerland 30/05/2006 and pharmaceutical uses 29/11/2005 therof

Merck & Co. Inc & 126, East Lincoln Istituto Di Ricerche Di Avenue , Rahway, Filing Date: 29/11/2005 Potassium salt of an HIV Biologia Molecolare P Warrant signed on 3123 NJ07065, USA & Via Rec: 7823 /4 dt Wef: 03/12/2004 Vide PT 3123 integrase inhibitor Angeletti S.P.A 19/06/2006 Pontina KM30,600 01/12/2005 Att: Dr Maria Chetcuti I-00040 Pomezia, Italy Cauchi

Ronda del General Mitre Filing Date: 30/11/2005 New pyridothienopyrimidine Almirall Prodesfarma Warrant signed on 3124 151, 08022 Barcelona, Rec: 7828/9 dt Wef: 30/11/2004 Vide PT 3124 derivatives Att: SS & Co 30/05/2006 Spain 01/12/2005

Ronda del General Mitre Filing Date: 30/11/2005 New pyridothienopyrimidine Almirall Prodesfarma Warrant signed on 3125 151, 08022 Barcelona, Rec: 7831/2 dt Wef: 30/11/2004 Vide PT 3125 derivatives Att: SS & Co 30/05/2006 Spain 01/12/2005

One Amgen Center Filing Date: 30/11/2005 Substituted heterocycles and Amgen Inc. Warrant signed on 3126 Drive, Thousand Oaks, Rec: 7825/6 dt Wef: 30/11/2004 Vide PT 3126 methods of use Att: Dr M. Chetcuti Cauchi 30/05/2006 CA 91320-1799, USA 01/12/2005

Glaxo Wellcome House, Berkeley Avenue, Glaxo Group Limited & Wef: 01/12/2004 Greenford, Middlesex Filing Date: 01/12/2005 Methods of treatment and Laboratories Fournier Wef: 17/06/2005 Warrant signed on 3127 UB60NN, Great Britain & Rec: 7838/9 dt Vide PT 3127 prevention S.A., Wef: 29/09/2005 19/06/2006 42 rue de Longvic, 01/12/2005 Att: SS & Co Wef: 07/10/2005 21300 Chenove, France

N-Substituted benzimidazolyl 58, South Service Road, Filing Date: 01/12/2005 - C - Kit Inhibitors and OSI Pharmaceuticals Inc. Suite 110, Melville, NY Warrant signed on 3128 Rec: 7841/2 dt Wef: 01/12/2004 Vide PT 3128 combinatorial benzimidazole Att: SS & Co 11747 19/06/2006 01/12/2005 library USA SmithKline Beecham One Franklin Plaza, PO Filing Date: 02/12/2005 Warrant signed on 3129 Medical combinations Corporation Box 7929, Philadelphia, Rec: 7863/5 dt Wef: 06/12/2004 Vide PT 3129 19/06/2006 Att: SS & Co PA 19101, USA 02/12/2005

SmithKline Beecham One Franklin Plaza, PO Filing Date: 02/12/2005 Warrant signed on 3130 Medical combinations Corporation Box 7929, Philadelphia, Rec: 7860/1 dt Wef: 06/12/2004 Vide PT 3130 19/06/2006 Att: SS & Co PA 19101, USA 02/12/2005

Janssen Pharmaceutica Filing Date: 05/12/2005 Treatment of latent Turnhoutseweg 30, B- Wef: 24/12/2004 Warrant signed on 3132 N.V. Rec: P585548 dt Vide PT 3132 tubercolosis 2340 Beerse, Belgium Wef: 08/06/2005 03/07/2006 Att: EMD Advocates 05/12/2005

Janssen Pharmaceutica Filing Date: 05/12/2005 Oral suspenion comprising Turnhoutseweg 30, B- Warrant signed on 3133 N.V. Rec: P585548 dt Wef: 06/12/2004 Vide PT 3133 meloxicam 2340 Beerse, Belgium 19/06/2006 Att: EMD Advocates 05/12/2005 Janssen Pharmaceutica Filing Date 05/12/2005 MTK 1 quinazoline Turnhoutseweg 30, B- Warrant signed on 3134 N.V. Rec P585584 of Wef: 08/12/2004 Vide PT 3134 derivatives 2340 Beerse, Belgium 19/06/2006 Att: EMD Advocates 05/12/2005

Janssen Pharmaceutica Filing Date: 05/12/2005 2,4 (4,6) pyrimidine Turnhoutseweg 30, B- Warrant signed on 3135 N.V. Rec: P585548 dt Wef: 08/12/2004 Vide PT 3135 derivatives 2340 Beerse, Belgium 19/06/2006 Att: EMD Advocates 05/12/2005

Filing Date: 06/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3136 Chemical process Rec: 7993/5 dt Wef: 16/12/2004 Vide PT 3136 Att: SS & Co Sweden 03/07/2006 06/12/2005

Filing Date: 06/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 17/12/2004 Warrant signed on 3137 Chemical compounds Rec: 7990/1 dt Vide PT 3137 Att: SS & Co Sweden Wef: 30/07/2005 03/07/2006 06/12/2005

Filing Date: 06/12/2005 Pharmaceutically useful salts AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3138 Rec: 7984/5 dt Wef: 16/12/2004 Vide PT 3138 of carboxylic acid derivatives Att: SS & Co Sweden 03/07/2006 06/12/2005

Filing Date: 06/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3139 Novel compounds Rec: 7987/8 dt Wef: 15/12/2004 Vide PT 3139 Att: SS & Co Sweden 19/06/2006 06/12/2005

Groot Begugrhof , Ku Leuven Research & Benedens troat 58, B- 7- (2-Cyclohexylidene- Filing Date: 06/12/2005 Development & 3000 Leuven, Belgium & Warrant signed on 3141 ethylidene) - Spiro [4,5] Rec: 8019/20 dt Wef: 06/12/2004 Vide PT 3141 Universiteit Gent Siut Pietersnieuvstoat 19/06/2006 decanes 07/12/2005 Att: Dr M. Chetcuti Cauchi 25, B-9000 Geut, Belgium

Triazole substituted Filing Date: 09/12/2005 LEO Pharma A/S Industrpouker 55, DK- Wef: 13/12/2004 Warrant signed on 3142 aminobenzophenone Rec: 8032/3 dt Vide PT 3142 Att: SS & Co 2750 Ballerup, Denmark Wef: 16/12/2004 19/06/2006 compounds 09/12/2005 Filing Date: 09/12/2005 Manufacture Process of Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3143 Rec: 8035/6 dt Wef: 16/12/04 Vide PT 3143 Organic Compounds Att: SS & Co Basel, Switzerland 03/07/2006 09/12/2005

New benzothiazine and benzothiadiazine compounds, a process for 12, Place de la Defense, Filing Date 09/12/2005 Les Laboratories Servier Warrant signed on 3144 their preparation and 92415 Courbevoie Rec: 8038/9 dt Wef: 10/12/2004 Vide PT 3144 Att: SS & Co 19/06/2006 pharmaceutical Cedex, France 09/12/2005 compositions containing them

Filing Date: 09/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3145 Therapeutic agents Rec: 8040/1 dt Wef: 17/12/2004 Vide PT 3145 Att: SS & Co Sweden 03/07/2006 09/12/2005

Block copolymers of polyethylene terephthalate Carl-Bosch-Strasse 38, Filing Date: 09/12/2005 and of the polyamide BASF Aktiengesellschaft Warrant signed on 3146 67056 Ludwigshafen, Rec: 8042/3 dt Wef: 09/12/2004 Vide PT 3146 composed of meta- Att: SS & Co 19/06/2006 Germany 09/12/2005 xylyenediamine and adipic acid

P.O. Box 4000, Route Bristol-Myers Squibb 206 and Province Line Filing Date: 09/12/2005 Heterocyclic compounds as Wef: 08/12/2004 Warrant signed on 3147 Company Road, Princeton, New Rec: 8053/4 dt Vide PT 3147 inhibitors of factor VIIA Wef: 02/11/2005 19/06/2006 Att: MAMO TCV Advocates Jersey 08543-4000, 09/12/2005 USA

Dylouronudeosides and SICOR Inc. 19, Hughes, Irvine, Filing Date: 09/12/2005 Warrant signed on 3148 process for preparation Att: CCA Interserv Ltd California 92618, United Rec: 8056/7 dt Wef: 08/12/2004 Vide PT 3148 19/06/2006 thereof Dr M. Chetcuti Cauchi States of America 09/12/2005

Lichstrasse 35, 4056 Basel, Switzerland & Novartis AG & SIGMA TVA Filing Date: 12/12/2005 Combinations of therapeutic Farmaceutiche Ricenite Warrant signed on 3149 Industrie Rec: 8092/3 dt Wef: 15/12/2004 Vide PT 3149 agents for treating cancer S.p.A., Viale 19/06/2006 Att: SS & Co 12/12/2005 Shakespeare 47, 00144 Roma, Italy

Filing Date: 12/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3150 Novel compounds Rec: 8089/90 dt Wef: 17/12/2004 Vide PT 3150 Att: SS & Co Sweden 03/07/2006 12/12/2005

Filing Date:12/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3151 Compounds Rec: 8086/7 dt Wef: 17/12/2004 Vide PT 3151 Att: SS & Co Sweden 03/07/2006 12/12/2005 Filing Date: 12/12/2005 Novartis AG Lichtrasse 35, 4056 Warrant signed on 3152 Organic compounds Rec: 8083/4 dt Wef: 14/12/2004 Vide PT 3152 Att: SS & Co Basel, Switzerland 19/06/2006 12/12/2005

Filing Date: 12/12/2005 Novartis AG Lichtrasse 35, 4056 Warrant signed on 3153 Dipeptide nitriles Rec: 8080/1 dt Wef: 14/12/2004 Vide PT 3153 Att: SS & Co Basel, Switzerland 19/06/2006 12/12/2005

Filing Date: 12/12/2005 Wef: 14/12/2004 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3154 Chemical compounds Rec: 8077/8 dt Wef: 13/04/2005 Vide PT 3154 Att: SS & Co Sweden 19/06/2006 12/12/2005 Wef: 07/10/2005

3-AMINO- PYRAZOLO[3,4b]PYRIDINES Filing Date: 12/12/2005 AS INHIBITORS OF PROTIEN Schering AG Warrant signed on 3156 Berlin 13342, Germany Rec: 8113/4 dt Wef: 14/12/2004 Vide PT 3156 TYROSINE KINASES, THEIR Att: MAMO TCV Advocates 19/06/2006 14/12/2005 PRODUCTION AND USE AS PHARMACEUTICAL AGENTS

Metasubstituted Filing Date: 12/12/2005 thiazolidinones, their Schering AG Wef: 15/12/2004 Warrant signed on 3157 Berlin 13342, Germany Rec: 8110/1 dt Vide PT 3157 manufacture and use as a Att: MAMO TCV Advocates Wef: 22/12/2004 22/08/2006 14/12/2005 drug

New triazine derivatives, procedures for their Filing Date: 14/12/2005 ISDIN, S.A. AV, Diagonal, 520, Warrant signed on 3158 preparation and their use as Rec: 8218/9 dt Wef: 16/12/2004 Vide PT 3158 Att: MAMO TCV Advocates 09006, Barcelona, Spain 03/07/2006 protective agents against UV 20/12/2005 radiation

P.O. Box 4000, Route Bristol-Myers Squibb 206 and Province Line Filing Date: 14/12/2005 Crystalline forms of a factor Wef: 15/12/2004 Warrant signed on 3159 Company Road, Princeton, New Rec: 8123/4 dt Vide PT 3159 XA inhibitor Wef: 18/11/2005 19/06/2006 Att: MAMO TCV Advocates Jersey 08543-4000, 14/12/2005 USA

P.O. Box 4000, Route Pyridyl-substituted spiro- Bristol-Myers Squibb 206 and Province Line Filing Date: 14/12/2005 Wef: 14/12/2004 Warrant signed on 3160 hydantoin compounds and Company Road, Princeton, New Rec: 8126/7 dt Vide PT 3160 Wef: 13/11/2005 19/06/2006 use thereof Att: MAMO TCV Advocates Jersey 08543-4000, 14/12/2005 USA

P.O. Box 4000, Route Pyridyl-substituted spiro- Bristol-Myers Squibb 206 and Province Line Filing Date: 14/12/2005 Wef: 14/12/2004 Warrant sigend on 3161 hydantoin compounds and Company Road, Princeton, New Rec: 8129/30 dt Vide PT 3161 Wef: 13/12/2005 19/06/2006 use thereof Att: MAMO TCV Advocates Jersey 08543-4000, 14/12/2005 USA Applied Research Filing Date: 15/12/2005 Treatment of hepatitis C in Putermaai 15, Curacae, Wef: 16/12/2004 Warrant signed on 3162 Systems Rec: 8160/1 dt Vide PT 3162 the Asian population Netherlands Antilles Wef: 20/12/2004 03/07/2006 Att: Dr M. Chetcuti Cauchi 19/12/2005

Fused pyrazole derivatives Arena Pharmaceuticals 6166 Nancy Ridge Drive, Filing Date: 15/12/2005 and methods of treatment of Wef: 23/12/2004 Warrant signed on 3163 Inc. San Diego, California Rec: 8163/4 dt Vide PT 3163 metabolic - related disorders Wef: 29/04/2005 03/07/2006 Att: Dr M. Chetcuti Cauchi 92121, USA 19/12/2005 thereof

Crystalline forms of (R)-8 - Arena Pharmaceuticals 6166 Nancy Ridge Drive, Filing Date: 15/12/2005 Chloro - 1- methyl- 2,3,4,5 - Warrant signed on 3164 Inc. San Diego, California Rec: 8157/8 dt Wef: 21/12/2004 Vide PT 3164 tetrahydro - 1H - 3 - 03/07/2006 Att: Dr M. Chetcuti Cauchi 92121, USA 19/12/2005 benzazepine

One Amgen Center Filing Date: 15/12/2005 Therapeutic formulations of Amgen Inc. Wef: 15/12/2004 Warrant signed on 3165 Drive, Thousand Oaks, Rec: 8154/5 dt Vide PT 3165 keratinocyte growth factor Att: Dr M. Chetcuti Cauchi Wef: 12/12/2005 19/06/2006 CA 91320-1799, USA 19/12/2005

Filing Date: 16/12/2005 Manufacture process of Novartis AG Lichstrasse 35, 4056 Warrant signed on 3166 Rec: 8188/9 dt Wef: 10/12/2004 Vide PT 3166 organic compounds Att: SS & Co Basel, Switzerland 03/07/2006 19/12/2005

Filing Date: 16/12/2005 Novartis AG Lichstrasse 35, 4056 Warrant signed on 3167 Organic compounds Rec: 8185/6 dt Wef: 22/12/2004 Vide PT 3167 Att: SS & Co Basel, Switzerland 03/07/2006 19/12/2005

12, place de la Defense, New benzo [b] pyrano [3,2-h] Les Laboratoires Servier & 92415 Courbevoie cridin-7- One cinnamate Centre National de la Cedex, France & 3, Rue Compounds, a process for Recherche Scientifique Michel Ange, 75794 Filing Date: 16/12/2005 Warrant signed on 3168 their preparation & (CNRS) & Universite Rene Paris Cedex 16, France Rec: 8182/3 dt Wef: 22/12/2004 Vide PT 3168 03/07/2006 pharmaceutical Descartes Paris V & 19/12/2005 compositions containing Att: SS & Co 12, rue de l'Ecole de them Medecine, 75270 Paris Cedex 06, France

Eastern Point Road, Filing Date: 16/12/2005 Pfizer Products Inc. Wef: 21/12/2004 Warrant signed on 3169 Macrolides Groton, Connecticut Rec: 8179 /80 dt Vide PT 3169 Att: SS & Co Wef: 14/09/2005 03/07/2006 06340, USA 19/12/2005

Solid dosage form Filing Date: 16/12/2005 comprising proton pump AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3170 Rec: 8176/7 dt Wef: 22/12/2004 Vide PT 3170 inhibitor and suspension Att: SS & Co Sweden 03/07/2006 19/12/2005 made therof

Filing Date: 16/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 21/12/2004 Warrant signed on 3171 Therapeutic agents 1 Rec: 8173/4 dt Vide PT 3171 Att: SS & Co Sweden Wef: 15/07/2005 03/07/2006 19/12/2005 Filing Date: 16/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3172 Chemical compounds Rec: 8170/1 dt Wef: 21/12/2004 Vide PT 3172 Att: SS & Co Sweden 03/07/2006 19/12/2005

Filing Date: 16/12/2005 A process for the purification Zambon Group S.p.A. Via della Chimica, 9, Warrant signed on 3173 Rec: 8167/8 dt Wef: 17/12/2004 Vide PT 3173 of gabapentin Att: SS & Co 36100 - Vincenza, Italy 03/07/2006 19/12/2005

Reducing carbohydrate Filing Date: 16/12/2005 derivatives of adamantane Forest Laboratories, Inc. 909 Third Avenue, New Warrant signed on 3174 Rec: 8213/4 dt Wef: 16/12/2004 Vide PT 3174 amines, and synthesis and Att: Dr M. Chetcuti Cauchi York, NY10022, USA 03/07/2006 19/12/2005 methods of use thereof

3-5-disubstituted and 3,5,7 - trisubstituted- 3H-oxazolo Anadys Pharmaceuticals, 3115 Merryfield Row, Filing Date: 19/12/2005 Wef: 17/12/2004 Warrant signed on 3175 and 3H thiazolo [4,5-d] Inc. San Diego, California Rec: 8228/9 dt Vide PT 3175 Wef: 17/12/2004 03/07/2006 pyrimidin-2 one compounds Att: Bezzina & Mifsud 92121, USA 20/12/2005 and prodrugs thereof

Anadys Pharmaceuticals, 3115 Merryfield Row, Filing Date: 19/12/2005 Warrant signed on 3176 Pyridazinone compounds Inc. San Diego, California Rec: 8225/6 dt Wef: 17/12/2004 Vide PT 3176 03/07/2006 Att: Bezzina & Mifsud 92121, USA 20/12/2005

Aminopyrimidine One Amgen Center Filing Date: 19/12/2005 Amgen Inc. Warrant signed on 3177 compounds and methods of Drive, Thousand Oaks, Rec: 8222/3 dt Wef: 17/12/2004 Vide PT 3177 Att: Bezzina & Mifsud 03/07/2006 use CA 91320-1799, USA 20/12/2005

Substituted triazolone, Janssen Pharmaceutica Filing Date: 20/12/2005 tetrazolone and imidazolone Turnhoutseweg 30, B- Wef: 21/12/2004 Warrant signed on 3178 N.V. Rec: 8245/6 dt Vide PT 3178 derivatives for use as a 2340 Beerse, Belgium Wef: 03/06/2005 19/06/2006 Att: EMD Advocates 20/12/2005 medicine

Transdermal Patch with Filing Date: 20/12/2005 progesterone A-specific Schering AG. Warrant signed on 3179 Berlin 13342, Germany Rec: 8254/5 dt Wef: 20/12/2004 Vide PT 3179 ligands (PRASL) as active Att: MAMO TCV Advocates 03/07/2006 20/12/2005 ingredient

Piperidine derivatives and Filing Date: 20/12/2005 Schering AG. Warrant signed on 3180 their use as anti-inflammatry Berlin 13342, Germany Rec: 8257/8 dt Wef: 20/12/2004 Vide PT 3180 Att: MAMO TCV Advocates 03/07/2006 agents 20/12/2005

Quinoline derivative, it's use, Filing Date: 20/12/2005 production and Schering AG. Warrant signed on 3181 Berlin 13342, Germany Rec: 8260/1 dt Wef: 22/12/2004 Vide PT 3181 pharmaceutical agents Att: MAMO TCV Advocates 03/07/2006 20/12/2005 containing the latter Salfonamido-macrocycles and the salts thereof, a pharmaceutical composition Filing Date: 20/12/2005 Schering AG. Warrant signed on 3182 comprising these Berlin 13342, Germany Rec: 8263/4 dt Wef: 22/12/2004 Vide PT 3182 Att: MAMO TCV Advocates 03/07/2006 compounds, the method of 20/12/2005 preparing and the use thereof

Sulfonamido-macrocycles as tie 2 inhibitors and the salt thereof, a pharmaceutical Filing Date 20/12/2005 Schering AG. Warrant signed on 3183 composition comprising Berlin 13342, Germany Rec: 8267/8 dt Wef: 22/12/2004 Vide PT 3183 Att: MAMO TCV Advocates 03/07/2006 these compounds, the 20/12/2005 method of preparing and the use thereof

Tricyclic amino alcohols, Filing Date: 20/12/2005 processes for synthesis of Schering AG. Warrant signed on 3184 Berlin 13342, Germany Rec: 8270/1 dt Wef: 22/12/2004 Vide PT 3184 same and use of same as Att: MAMO TCV Advocates 03/07/2006 20/12/2005 anti-inflammatory drugs

Composition comprising an Filing Date: 20/12/2005 epothilone and methods for Schering AG. Wef: 23/12/2004 Warrant signed on 3185 Berlin 13342, Germany Rec: 8273 +8274 dt Vide PT 3185 producing a composition Att: MAMO TCV Advocates 03/07/2006 20/12/2005 comprising an epothilone

Filing Date: 20/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 23/12/2004 Warrant signed on 3186 Therapeutic agents Rec: 8294/5 dt Vide PT 3186 Att: SS & Co Sweden Wef: 29/06/2005 03/07/2006 20/12/2005

Filing Date: 20/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 23/12/2004 Warrant signed on 3187 Therapeutic agents Rec: 8291/2 dt Vide PT 3187 Att: SS & Co Sweden Wef: 13/07/2005 03/07/2006 20/12/2005

Filing Date: 20/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3188 Amide derivatives Rec: 8288/9 dt Wef: 22/12/2004 Vide PT 3188 Att: SS & Co Sweden 03/07/2006 20/12/2005

Filing Date: 20/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 24/12/2004 Warrant signed on 3189 Chemical compounds Rec: 8285/6 dt Vide PT 3189 Att: SS & Co Sweden Wef: 14/04/2005 03/07/2006 20/12/2005

6701 Kaiser Drive, Abgenix Inc. & Fremont, California Filing Date: 20/12/2005 Antibodies directed to angio Wef: 21/12/2004 Warrant signed on 3190 AstraZeneca AB 94555, United States of Rec: 8282/3 dt Vide PT 3190 poietin- 2 and uses thereof Wef: 25/08/2005 03/07/2006 Att: SS & Co America & SE-15185 20/12/2005 Sodertalje, Sweden Filing Date: 20/12/2005 AstraZeneca AB SE-15185 Sodertalje, Warrant signed on 3191 Chemical compounds Rec: 8279/80 dt Wef: 22/12/2004 Vide PT 3191 Att: SS & Co Sweden 03/07/2006 20/12/2005

SmithKline Beecham One Franklin Plaza, PO Filing Date: 20/12/2005 Warrant signed on 3192 Methods and formulations Corporation Box 7929, Philadelphia, Rec: 8276/7 dt Wef: 21/12/2004 Vide PT 3192 03/07/2006 Att: SS & Co PA 19101, USA 20/12/2005

Substituted heterocyclic One Amgen Center Filing Date: 20/12/2005 Amgen Inc. Warrant signed on 3193 compounds and methods of Drive, Thousand Oaks, Rec: 8297/8 dt Wef: 20/12/2004 Vide PT 3193 Att: Dr M. Chetcuti Cauchi 03/07/2006 use CA 91320-1799, USA 20/12/2005

Applied Research Filing Date: 21/12/2005 Sulfonyl amino cyclic Pietermaai 15, Curacao, Wef: 21/12/2004 Warrant signed on 3194 Systems ARS Holding N.V. Rec: 8392/3 dt Vide PT 3194 derivatives and use thereof Netherlands Antilles Wef: 22/12/2004 03/07/2006 Att: Dr M. Chetcuti Cauchi 23/12/2005

Applied Research Filing Date: 21/12/2005 Novel cc-chemokine Pietermaai 15, Curacao, Wef: 21/12/2004 Warrant signed on 3195 Systems ARS Holding N.V. Rec: 8308/9 dt Vide PT 3195 antagonists Netherlands Antilles Wef: 21/12/2004 03/07/2006 Att: Dr M. Chetcuti Cauchi 21/12/2005

Method and systems for Applied Research Filing Date: 21/12/2005 Pietermaai 15, Curacao, Warrant signed on 3196 identifying gene-trait Systems ARS Holding N.V. Rec: 8311/2 dt Wef: 21/12/2004 Vide PT 3196 Netherlands Antilles 03/07/2006 linkages Att: Dr M. Chetcuti Cauchi 21/12/2005

Glaxo Wellcome House, Wef: 23/12/2004 Glaxo Group Limited Berkeley Avenue, Filing Date: 22/12/2005 Warrant signed on 3197 Compounds Wef: 26/04/2005 Vide PT 3197 Att: SS & Co Greenford, Middlesex Rec: 8336/7dt 22/12/2005 03/07/2006 Wef: 21/12/2005 UB60NN, Great Britian

Glaxo Wellcome House, Filing Date: 22/12/2005 Wef: 23/12/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3198 Compounds Rec: 8339/40 dt Wef: 05/04/2005 Vide PT 3198 Att: SS & Co Greenford, Middlesex 03/07/2006 22/12/2005 Wef: 29/11/2005 UB60NN, Great Britian

Glaxo Wellcome House, Filing Date: 22/12/2005 Wef: 23/12/2004 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3199 Compounds Rec: 8342/3 dt Wef: 05/05/2005 Vide PT 3199 Att: SS & Co Greenford, Middlesex 03/07/2006 22/12/2005 Wef: 29/11/2005 UB60NN, Great Britian

Filing Date: 22/12/2005 AstraZeneca AB SE-15185 Sodertalje, Wef: 24/12/2004 Warrant signed on 3200 Method Rec: 8345/6 dt Vide PT 3200 Att: SS & Co Sweden Wef: 06/10/2005 03/07/2006 22/12/2005 Novel benzo-fused heteroaryl Janssen Pharmaceutica Filing Date: 22/12/2005 Turnhoutseweg 30, B- Warrant signed on 3201 sulfomide derivatives useful N.V. Rec: 8369/70 dt Wef: 22/08/2005 Vide PT 3201 2340 Beerse, Belgium 23/10/2007 as anticonvulsant agents Att: EMD Advocates 22/12/2005

Novel sulfamate and Janssen Pharmaceutica Filing Date: 22/12/2005 sulfamide derivatives useful Turnhoutseweg 30, B- Warrant signed on 3202 N.V. Rec: 8366/7 dt Wef: 16/06/2005 Vide PT 3202 for the treatment of epilepsy 2340 Beerse, Belgium 11/01/2007 Att: EMD Advocates 22/12/2005 and related disorders

Compositions and methods One Amgen Center Filing Date: 22/12/2005 Amgen Inc. Warrant signed on 3203 relating to anti-IgF-1 receptor Drive, Thousand Oaks, Rec: 8389/90 dt Wef: 22/12/2004 Vide PT 3203 Att: Dr M. Chetcuti Cauchi 03/07/2006 antibodies CA 91320-1799, USA 23/12/2005

Applied Research Filing Date: 22/12/2005 Combination treatment for Pietermaai 15, Curacao, Wef: 22/12/2004 Warrant signed on 3204 Systems ARS Holding N.V. Rec: 8386/7 dt Vide PT 3204 multiple sclerosis Netherlands Antilles Wef: 15/02/2006 03/07/2006 Att: Dr M. Chetcuti Cauchi 23/12/2005 MT PT No Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract

Cladribine regimen for Applied Research Systems Pietermaai 15, Curacao, Filing Date: 22/12/2005 Wef: 22/12/2004 Warrant signed on 3205 treating multiple ARS Holdings NV Netherlands Vide PT 3205 Rec: 8383/4 dt 23/12/2005 Wef: 22/12/2004 03/07/2006 sclerosis Att: CC Advocates Antilles

1- Aminocyclohexane derivatives for the Merz Pharma GmBH & Co 100 Eckenheimer treatment of multiple Filing Date: 22/12/2005 Warrant signed on 3206 KGAA Landstrasse, D-60318 Wef: 22/12/2004 Vide PT 3206 sclerosis emotional Rec: 8412/3 dt 27/12/2005 03/07/2006 Att: CCA Interserv Ltd Frankfurt, Germany liability and pseudo bulbar effect

Novel ligands that modulate RAR receptors, Galderma Research & 635 Route des Lucioles, Filing Date: 23/12/2005 Warrant signed on 3207 and use thereof in human Development, SNC. BP 87, 06902 Sophia Wef: 23/12/2004 Vide PT 3207 Rec: 8404/5 dt 23/12/2005 03/07/2006 medicine and in Att: Bezzina Mifsud Antipolis Cedex , France cosmetics

Certain thienopyrimidine 100 Philips Parkway, derivatives as Memory Pharmaceuticals Corp Filing Date: 23/12/2005 Warrant signed on 3208 Montvale, New Jersey Wef: 23/12/2004 Vide PT 3208 phosphodiesterase 10 Att: J Mifsud Rec: 8415/6 dt 27/12/2005 03/07/2006 07645, USA inhibitors

Novartis AG Lichstrasse 35, 4056 Filing Date: 27/12/2005 Warrant signed on 3210 Organic compounds Wef: 30/12/2004 Vide PT 3210 Att: S S & Co Basel, Switzerland Rec: 8449/50 dt 27/12/2005 03/07/2006

Indoles useful in the Biolipox AB PO Box 6280, SE-102 Filing Date: 27/12/2005 Warrant signed on 3211 treatment of Wef: 19/11/2005 Vide PT 3211 Att: S S & Co 34 Stockholm, Sweden Rec: 8452/3 dt 27/12/2005 01/08/2006 inflammation

Indoles useful in the Biolipox AB PO Box 6280, SE-102 Filing Date: 27/12/2005 Wef: 19/01/2005 Warrant signed on 3212 treatment of Vide PT 3212 Att: S S & Co 34 Stockholm, Sweden Rec: 8455/6 dt 27/12/2005 Wef: 19/01/2005 01/08/2006 inflammation

Indoles useful in the Biolipox AB PO Box 6280, SE-102 Filing Date: 27/12/2005 Warrant signed on 3213 treatment of Wef: 19/01/2005 Vide PT 3213 Att: S S & Co 34 Stockholm, Sweden Rec: 8458/9 of 27/12/2005 01/08/2006 inflammation

Novel pyrrolidyl Eastern Point Road, derivatives of Pfizer Products Inc. Filing Date: 27/12/2005 Warrant signed on 3214 Groton, Connecticut Wef: 31/12/2004 Vide PT 3214 heteroaromatic Att: SS & Co. Rec: 8461/2 dt 27/12/2005 21/07/2006 06340, USA compounds 1- (2-methylpropyl) - 1H - Imidozo [4,5 - C] [1,5] naphthyridin -4- amine Wef: 30/12/2004 3M Innovative Properties 3M Center, Saint Paul, ethanesulfonate and 1-(2- Filing Date: 28/12/2005 Wef: 16/08/2005 Warrant signed on 3215 Company Minnesota 55133, 3427, Vide PT 3215 methylpropyl) -1 H Rec: 14/15 dt 02/01/2006 Wef: 04/02/2005 03/07/2006 Att: Bezzina & Mifsud USA imidozo [4,5-C] [1,5] Wef: 12/07/2005 naphthyridin -4- amine methanesulfonate

Eastern Point Road, Heteroaromatic quinoline Pfizer Products Inc. Filing Date: 29/12/2005 Warrant signed on 3216 Groton, Connecticut Wef: 07/01/2005 Vide PT 3216 compounds Att: SS & Co. Rec: 17/18 dt 02/01/2006 21/07/2006 06340, USA

PO Box 4000, Route Azolo pyrimidine - based Brtistol Myers Squibb 206 and Province Line inhibitors of dipeptidyl Filing Date: 29/12/2005 Warrant signed on 3217 Company Road, Princeton, New Wef: 29/12/2004 Vide PT 3217 peptidase 1N and Rec: 6/7 dt 02/01/2006 03/07/2006 Att: MAMO TCV Advocates Jersey 08543-4000, methods USA

PO Box 4000, Route Aminium salts of 1,2,3- Brtistol Myers Squibb 206 and Province Line triazoles as prodrugs of Filing Date: 29/12/2005 Warrant signed on 3218 Company Road, Princeton, New Wef: 29/12/2004 Vide PT 3218 drugs including antiviral Rec: 9/10 dt 02/01/2006 03/07/2006 Att: MAMO TCV Advocates Jersey 08543-4000, agents USA

18- methyl -19- Nor -17- pregn -4- ene -21, 7- carbolactones, as well as Schering AG Filing Date: 29/12/2005 Warrant signed on 3219 Berlin 13342, Germany Wef: 30/12/2004 Vide PT 3219 pharmaceutical Att: MAMO TCV Advocates Rec: 11/12 dt 02/01/2006 11/01/2007 preaprations that contain latter

Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 03/01/2006 Wef: 06/01/2005 Warrant signed on 3220 Novel compounds Vide PT 3220 Att: S S & Co Sweden Rec: 54/55 dt 03/01/2006 Wef: 21/10/2005 21/07/2006

Wef: 07/01/2005 Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 03/01/2006 Wef: 18/11/2005 Warrant signed on 3221 Methods of Treatment Vide PT 3221 Att: S S & Co Sweden Rec: 51/52 dt 03/01/06 Wef: 18/11/2005 21/07/2006 Wef: 18/11/2005

PO Box 4000, Route 206 and Province Line Road, Princeton, New Brtistol Myers Squibb Prodrugs of potassium Jersey 08543-4000, Filing Date: 03/01/2006 Warrant signed on 3222 Company & ICAGEN Inc. Wef: 03/01/2005 Vide PT 3222 channel inhibitors USA & Suite 350, 4222 Rec: 6415 dt 03/01/2006 21/07/2006 Att: MAMO TCV Advocates Emperor Boulevard, Durcham, North Carolina 27703, USA Anilinic derivatives of isothiazol - 3 (2H)- one Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 06/11/2006 Wef: 10/01/2005 3223 WITHDRAWN Vide PT 3223 1,1 dioxide as liver X Att: S S & Co Sweden Rec: 147/148 dt 06/01/2006 Wef: 08/07/2005 receptor modulators

Non-anilnic derivatives of isothiazol - 3 (2H)- one Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 06/01/2006 3224 Wef: 10/01/2005 WITHDRAWN Vide PT 3224 1,1- dioxides as liver X Att: S S & Co Sweden Rec: 156/7 dt 06/01/2006 receptor modulators

Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 06/01/2006 Warrant signed on 3225 Chemical Compounds Wef: 13/01/2005 Vide PT 3225 Att: S S & Co Sweden Rec: 153/4 dt 06/01/2006 21/07/2006

Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 06/01/2006 Warrant signed on 3226 Benzamide derivatives Wef: 15/01/2005 Vide PT 3226 Att: S S & Co Sweden Rec: 150/151 dt 06/01/2006 21/07/2006

6166 Nancy Ridge Processes for Preparing Arena Pharmaceuticals Inc. Filing Date: 06/01/2006 Warrant signed on 3227 Drive, San Diego, Wef: 10/01/2005 Vide PT 3227 Aromatic Ethers Att: CC Advocates Rec: 161/2 dt 09/01/2006 21/07/2006 California 92121, U.S.A.

Filing date 06/01/06 Process for Preparing 6166 Nancy Ridge Arena Pharmaceuticals Inc. Rec 164/5 of 09/01/06 Warrant signed on 3228 Pyrazolo[3,4-d]Pyrimidine Drive, San Diego, Wef: 13/01/05 Vide PT 3228 Att: CC Advocates Claims Fee Lm 630 21/07/2006 Ethers California 92121, U.S.A. Rec 166 of 09/01/06

Substituted pyridinyl and pyrimidinyl derivatives 6166 Nancy Ridge as modulators of Arena Pharmaceuticals Inc. Filing Date: 06/01/2006 Warrant signed on 3229 Drive, San Diego, Wef: 10/01/2005 Vide PT 3229 metabolism and the Att: CC Advocates Rec: 167/168 dt 09/01/2006 21/07/2006 California 92121, U.S.A. treatment of disorders related thereto

Use of organice dyes for Schering AG Mullerstrasse 170-178, Filing Date: 09/01/2006 Warrant signed on 3230 the diagnosis of Wef: 07/01/2005 Vide PT 3230 Att: MAMO TCV Advocates Berlin 13342, Germany Rec: 182/183 dt 09/01/2006 21/07/2006 proliferative diseases

PO Box 4000, Route Phenylglycinamide Brtistol Myers Squibb 206 and Province Line Filing Date: 09/01/2006 Warrant signed on 3231 derivatives useful as Company Road, Princeton, New Wef: 10/01/2005 Vide PT 3231 Rec: 186/187 dt 09/01/2006 21/07/2006 anticoagulants Att: MAMO TCV Advocates Jersey 08543-4000, USA Combination therapy for the treatment of diabetes and conditions related 6166 Nancy Ridge Wef: 10/01/2005 thereto and for the Arena Pharmaceuticals Inc. Filing Date: 09/01/2006 Warrant signed on 3232 Drive, San Diego, Wef: 19/05/2005 Vide PT 3232 treatment of conditions Att: CC Advocates Rec: 222 dt 10/01/2006 21/07/2006 California 92121, U.S.A. Wef: 14/10/2005 ameliorated by increasing a blood GLP-1 Level

A 2-(cyclic aminocarbonyl) indoline 6-8 Dosho-nachi, 2- Dainippon Sumitomo Pharma derivative and a chome, Chino-ku, Osaka-Filing Date: 10/01/2006 Warrant signed on 3234 Co, Ltd Wef: 12/01/2005 Vide PT 3234 pharmaceutical shi, Osaka 541-8524, Rec: 211/212 dt 10/01/2006 21/07/2006 Att: S S & Co composition containing Japan thereof

Novartis AG Lichstrasse 35, 4056 Filing Date: 10/01/2006 Warrant signed on 3236 Organic compounds Wef: 14/01/2005 Vide PT 3236 Att: S S & Co Basel, Switzerland Rec: 217/218 dt 10/01/2006 21/07/2006

Substantially pure Teva Pharmaceutical Industries 5 Basel Street, PO Box tolterodine tartrate and Filing Date: 10/01/2006 Wef: 10/01/2005 Warrant signed on 3237 Ltd 3190, Petah Tiqva Vide PT 3237 process for preparing Re:c 225/226 dt 10/01/2006 Wef: 14/06/2005 21/07/2006 Attn: CCA Interserv Ltd 49131, Israel thereof

Teva Pharmaceutical Industries 5 Basel Street, PO Box Process for preparing Filing Date: 10/01/2006 Wef: 10/01/2005 Warrant signed on 3238 Ltd 3190, Petah Tiqva Vide PT 3238 Tolterodine Tartrate Rec: 228/9 dt 10/01/2006 Wef: 14/06/2005 21/07/2006 Attn: CCA Interserv Ltd 49131, Israel

PO Box 4000, Route Bicyclic heterocycles as Brtistol Myers Squibb 206 and Province Line Filing Date: 12/01/2006 Warrant signed on 3239 cannabinoid receptor Company Road, Princeton, New Wef: 12/01/2005 Vide PT 3239 Rec: 259/260 dt 12/01/2006 21/07/2006 modulators Att: MAMO TCV Advocates Jersey 08543-4000, USA

PO Box 4000, Route Bicyclic heterocycles as Brtistol Myers Squibb 206 and Province Line Filing Date: 12/01/2006 Warrant signed on 3240 cannabinoid receptor Company Road, Princeton, New Wef: 12/01/2005 Vide PT 3240 Rec: 262/263 dt 12/01/2006 21/07/2006 modulators Att: MAMO TCV Advocates Jersey 08543-4000, USA

PO Box 4000, Route Bicyclic heterocycles as Brtistol Myers Squibb 206 and Province Line Filing Date: 12/01/2006 Warrant signed on 3241 cannabinoid receptor Company Road, Princeton, New Wef: 12/01/2005 Vide PT 3241 Rec: 265/266 dt 12/01/2006 21/07/2006 modulators Att: MAMO TCV Advocates Jersey 08543-4000, USA Heterocyclic modulators PO Box 4000, Route of the glucocorticoid Brtistol Myers Squibb 206 and Province Line Filing Date: 13/01/2006 Warrant signed on 3242 receptor AP-1, and/or NF- Company Road, Princeton, New Wef: 13/01/2005 Vide PT 3242 Rec: 268/269 dt 13/01/2006 21/07/2006 kB activity and use Att: MAMO TCV Advocates Jersey 08543-4000, thereof USA

PO Box 4000, Route Modulators of the Brtistol Myers Squibb 206 and Province Line glucocorticoid receptor, Filing Date: 13/01/2006 Wef: 13/01/2005 Warrant signed on 3243 Company Road, Princeton, New Vide PT 3243 AP-1, and/or NF-KB Rec: 271/272 dt 13/01/2006 Wef: 12/01/2006 21/07/2006 Att: MAMO TCV Advocates Jersey 08543-4000, activity and use thereof USA

PO Box 4000, Route Modulators of the Brtistol Myers Squibb 206 and Province Line glucocorticoid receptor, Filing Date: 13/01/2006 Warrant signed on 3244 Company Road, Princeton, New Wef: 13/01/2005 Vide PT 3244 AP-1, and/or NF-KB Rec: 274/275 dt 13/01/2006 21/07/2006 Att: MAMO TCV Advocates Jersey 08543-4000, activity and use thereof USA

Substituted heteroaryl PO Box 4000, Route amide modulators of Brtistol Myers Squibb 206 and Province Line Filing Date: 13/01/2006 Wef: 13/01/2005 Warrant signed on 3245 glucocorticoid receptor, Company Road, Princeton, New Vide PT 3245 Rec: 277/278 dt 13/01/2006 Wef: 12/01/2006 01/08/2006 AP-1, and/or NF-KB Att: MAMO TCV Advocates Jersey 08543-4000, activity and use thereof USA

Direct compression Novartis AG Lichstrasse 35, 4056 Filing Date: 13/01/2006 Wef: 18/01/2006 Warrant signed on 3246 Vide PT 3246 formulations and process Att: S S & Co Basel, Switzerland Rec: 289/290 dt 13/01/2006 Wef: 14/06/2005 01/08/2006

Novel benzamide Astrazeneca AB SE 151 85 Sodertalje, Filing Date: 13/01/2006 Warrant signed on 3247 Wef: 20/01/2005 Vide PT 3247 derivatives Att: S S & Co Sweden Rec: 292/293 dt 13/01/2006 01/08/2006

Certain substituted ureas 36 East Industrial Road, CGI Pharmaceuticals Inc. Filing Date: 16/01/2006 Wef: 14/01/2005 Warrant signed on 3248 as modulators of kinase Branford, CT 06405, Vide PT 3248 Att: Bezzina & Mifsud Rec: 441/442 dt 23/01/2006 Wef: 02/01/2005 02/07/2006 activity USA

436 Cambridge Science Wef: 21/01/2005 Pharmaceutical Astex Therapeutics Limited Park, Micton Road , Filing Date: 17/01/2006 Wef: 22/01/2005 Warrant signed on 3249 Vide PT 3249 compounds Att: S S & Co Cambridge CB4 0QA, Rec: 330/331 dt 17/01/2006 Wef: 27/01/2005 01/08/2006 United Kingdom Wef: 09/02/2005

436 Cambridge Science Wef: 21/01/2005 Pharmaceutical Astex Therapeutics Limited Park, Micton Road , Filing Date: 17/01/2006 Wef: 22/01/2005 Warrant signed on 3250 Vide PT 3250 compounds Att: S S & Co Cambridge CB4 0QA, Rec: 333/334 dt 17/01/2006 Wef: 27/01/2005 01/08/2006 United Kingdom Wef: 09/02/2005 436 Cambridge Science Wef: 21/01/2005 Pharmaceutical Astex Therapeutics Limited Park, Micton Road , Filing Date: 17/01/2006 Wef: 22/01/2005 Warrant signed on 3251 Vide PT 3251 compounds Att: S S & Co Cambridge CB4 0QA, Rec: 336/337 dt 17/01/2006 Wef: 27/01/2005 01/08/2006 United Kingdom Wef: 09/02/2005

436 Cambridge Science Pharmaceutical Astex Therapeutics Limited Park, Micton Road , Filing Date: 17/01/2006 Wef: 21/01/2005 Warrant signed on 3252 Vide PT 3252 compounds Att: S S & Co Cambridge CB4 0QA, Rec: 339/340 dt 17/01/2006 Wef: 22/01/2005 01/08/2006 United Kingdom

Substituted triazole Ramsgate Road, Pfizer Limited Filing Date: 17/01/2006 Warrant signed on 3253 derivatives as oxytocin Sandwich, Kent CT13 Wef: 20/01/2005 Vide PT 3252 Att: S S & Co Rec: 342/343 dt 17/01/2006 01/08/2006 antagonists 9N5, England

Methods of use of dual PPAR agonist compounds and drug Novartis AG Lichstrasse 35, 4056 Filing Date: 17/01/2006 Warrant signed on 3254 Wef: 18/01/2005 Vide PT 3254 delivery devices Att: S S & Co Basel, Switzerland Rec: 345/346 dt 17/01/2006 01/08/2006 containing such compounds

PO Box 4000, Route Bicyclic heterocycles as Brtistol Myers Squibb 206 and Province Line Filing Date: 18/01/2006 Warrant signed on 3255 cannaboid receptor Company Road, Princeton, New Wef: 18/01/2005 Vide PT 3255 Rec: 404/405 dt 23/01/2006 01/08/2006 modulators Att: MAMO TCV Advocates Jersey 08543-4000, USA

PO Box 4000, Route Brtistol Myers Squibb 206 and Province Line Heteroaryl compounds as Filing Date: 18/01/2006 Wef: 19/01/2005 Warrant signed on 3256 Company Road, Princeton, New Vide PT 3256 P2Y, receptor inhibitors Rec: 407/408 dt 23/01/2006 Wef: 09/12/2005 01/08/2006 Att: MAMO TCV Advocates Jersey 08543-4000, USA

Head Administrator, 4-1, Method for preventing Kinki University Hiroaki SEKO 3-chome, Kawakal, Filing Date: 18/01/2006 Wef: 21/01/2005 Warrant signed on 3257 abnormal behaviour of Vide PT 3257 Att: Mamo TCV Advocates Higashiosaka-shi, Rec: 410/411 dt 23/01/2006 Wef: 21/01/2005 01/08/2006 tumor Osaka 577-850, Japan

N-hydroxyamide Applied Research Systems Pietermaai 15, Curacao, Filing Date: 20/01/2006 Wef: 31/01/2005 Warrant signed on 3258 derivatives and use Vide PT 3258 Att: Dr M Chetcuti Cauchi Netherlands Antilles Rec: 393/394 dt 23/01/2006 Wef: 01/02/2005 01/08/2006 thereof

Vanilloid receptor ligands One Amgen Centre Amgen Inc Filing Date: 20/01/2006 Warrant signed on 3259 and their use in Drive, Thousand Oaks, Wef: 20/01/2005 Vide PT 3259 Att: Dr M Chetcuti Cauchi Rec: 402/403 dt 23/01/2006 01/08/2006 treatments CA 91320 - 1799, USA Process for preparing 6166 Nancy Ridge Arena Pharmaceuticals Inc. Filing Date: 20/01/2006 Warrant signed on 3260 Substituted Drive, San Diego, Wef: 26/01/2005 Vide PT 3260 Att: Dr M Chetcuti Cauchi Rec: 436/7 dt 23/01/2006 01/08/2006 Phenylpyrazole Ureas California 92121, U.S.A.

Eastern Point Road, P44 agonists and uses Pfizer Products Inc. Filing Date: 24/01/2006 Wef: 04/02/2005 Warrant signed on 3261 Groton, Connecticut Vide PT 3261 thereof Att: SS & Co. Rec: 481/482 dt 24/01/2006 Wef: 04/11/2005 22/08/2006 06340, USA MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No Filing date: 24/01/2006 Compounds and IRM LLC Hurst Holme, 12 Trott Road, Rec: 484/485 dt Warrant signed on 3262 Compositions as Protein Wef: 26/1/2005 Vide PT 3262 Att: SS & Co. Hamilton, Bermuda HM11 24/01/2006 01/08/2006 Kinase Inhibitors

Filing Date: 24/01/2006 Antibodies Against Abgenix Inc. 6701 Kaiser Drive, Freemont, Wef: 26/01/2005 Warrant signed on: 3263 Rec: 486/487 dt Vide PT 3263 Interleukin-1 beta Att: SS & Co. California 94555, USA Wef: 22/12/2005 01/08/2006 24/01/2006

Pyrazolopyridines and salts thereof, a Pharmaceutical Filing Date: 24/01/2006 Composition comprising Schering AG Warrant signed on: 3264 Berlin 13342, Germany Rec: 503/504 dt Wef: 24/01/2005 Vide PT 3264 said compounds, a method Att: Mamo TCV 01/08/2006 25/01/2006 of preparing same and use of same

Method of Conjugating One Amgen Centre Drive, Filing Date: 24/01/2006 Amgen Inc. Wef: 24/01/2005 Warrant signed on: 3265 Aminithiol Containing Thousand Oaks, California Rec: 547/548 dt Vide PT 3265 Att: Dr.M. Chetcuti Cauchi Wef: 23/01/2006 01/08/2006 Molecules to Vehicles 91320 - 1799, USA 25/01/2006

Use of Soluble CD164 Applied Research Systems Filing Date: 24/01/2006 Variants in Inflammatory Pietermaai 15, Curacao, Wef: 24/01/2005 Warrant signed on: 3266 ARS Holding NV Rec: 550/551 dt Vide PT 3266 and/or Autoimmune Netherlands Antilles Wef: 23/02/2005 01/08/2006 Att: CCA Interserv Ltd. 25/01/2006 Disorders

Filing Date: 26/01/2006 Janssen Pharmaceutica Turnhoutseweg 30, B-2340 Rec: 564/565 dt Warrant signed on: 3267 Anthelmintic Compounds N.V Wef: 28/01/2005 Vide PT 3267 Beerse, Belgium 26/01/2006 01/08/2006 Att: EMD Advocates

New heterocyclic oxime compounds, a process for Les Laboratoires Servier 12, Place De La Defense, Filing Date: 26/01/2006 their preparation and Warrant signed on: 3268 Att: SS & Co. 92415 Courbevoie Cedex, Rec: 596 dt 27/01/2006 Wef: 27/01/2005 Vide PT 3268 pharmaceutical 01/08/2006 France Rec: 575 dt 26/01/2006 compositions containing them

New Heterocyclicoxime Compounds, A Process for Les Laboratoires Servier 12, Place De La Defense, Filing Date: 26/01/2006 their Preparation and Warrant signed on: 3269 Att: SS & Co. 92415 Courbevoie Cedex, Rec: 572/573 dt Wef: 27/01/2005 Vide PT 3269 Pharmaceutical 01/08/2006 France 26/01/2006 Compositions Containing them Filing Date: 26/01/2006 Wef: 04/02/2005 Astrazeneca AB Warrant signed on: 3270 Chemical Compounds SE. 15185 Sodertalje, Sweden Rec: 578/579 dt Wef: 16/02/2005 Vide PT 3270 Att: SS & Co. 22/08/2006 26/01/2006 Wef: 26/09/2005

Filing Date: 27/01/2006 Lacosamide for add-on Schwarz Pharma AG Alfred-Nobel - Str 10, 40799 Wef: 28/01/2005 Warrant signed on: 3271 Rec: 587/588 dt Vide PT 3271 Therapy Att: GS Services Ltd. Monheim, Germany Wef: 28/01/2005 01/08/2006 27/01/2006

Tera Pharmaceutical Filing Date: 27/01/2006 5. Basel Street , PO Box 3190, Warrant signed on: 3272 Puloxetine HCL Polymorphs Industries Ltd. Rec: 602/603 dt Wef: 27/01/2005 Vide PT 3272 Petah Tiqva 49131, Israel 01/08/2006 Att: Dr.M Chetcuti-Cauchi 30/01/2006

Filing Date: 31/01/2006 Arrow International Ltd. 57, St Christopher Street, Warrant signed on: 3273 Nebulizer Formulation Rec: 635/536 dt Wef: 03/01/2005 Vide PT 3273 Att: SS & Co. Valletta VLT08, Malta 01/08/2006 31/01/2006

Compositions and Methods One Amgen Centre Drive, Filing Date: 02/02/2006 Amgen Inc. Warrant signed on: 3274 for Treating Fibrotic Thousand Oaks, California Rec: 696/697 dt Wef: 01/02/2005 Vide PT 3274 Att: Dr.M. Chetcuti Cauchi 22/08/2006 Disorders 91320 - 1799, USA 02/02/2006

Crystalline 1H-imidazo [4,5- b] pyridin-5-amine, 7-[5- [(cyclohexylomethylamino)- 6-10 Koishikawa, 4-Chome, Filing Date: 02/02/2006 Eisai Co Ltd. Warrant signed on: 3275 methyl]-1H-Indol-2-YL]-2- Bunkyo-Ku, Tokyo 112-8088, Rec: 693/694 dt Wef: 02/02/2005 Vide PT 3275 Att: MAMO TCV Advocates 22/08/2006 methyl,Sulfate(1:1), Japan 02/02/2006 trihydrate and its pharmaceutical uses

Thiazolidinones, their Filing Date: 02/02/2006 Schering AG Wef: 03/02/2005 Warrant signed on: 3276 Production and Use as Berlin 13342, Germany Rec: 690/691 dt Vide PT 3276 Att: MAMO TCV Advocates Wef: 10/02/2005 22/08/2006 Pharmaceutical Agents 02/02/2006

Modified Fusion Molecules The Regents of the 1111 Franklin Street, 12th Filing Date: 02/02/2006 Warrant signed on: 3277 for Treatment of Allergic University of California Floor , Oakland 94607-5200, Rec: 705/706 dt Wef: 02/02/2005 Vide PT 3277 22/08/2006 Disease Att: CCA Interserv Ltd. California, USA 02/02/2006

PO BOX 4000, Route 206 and Phenyl - Substituted Bristol-Myres Squibb Filing Date: 03/02/2006 Province Line Road, Princeton, Warrant signed on: 3278 Pyrimidine Compounds Company Rec: 715/716 dt Wef: 04/02/2005 Vide PT 3278 New Jersey 08543-4000, 22/08/2006 Useful as Kinase Inhibitors Att: MAMO TCV Advocates 06/02/2006 United States of America Lichtstrasse 35, 4056 Basel, Filing Date: 03/02/2006 Combination of Xolair with Novartis AG Warrant signed on: 3279 Switzerland Rec: 721/722 dt Wef: 04/02/2005 Vide PT 3279 Immunosupressive Agent Att: SS & Co. 22/08/2006 06/02/2006

Filing Date: 03/02/2006 Novel Salt Form of a Pfizer Limited Ramsgate Road, Sandwich, Warrant signed on: 3280 Rec: 724/725 dt Wef: 07/02/2005 Vide PT 3280 Dopamine Agonist Att: SS & Co. Kent CT 13 9NJ, England 22/08/2006 06/02/2006

Filing Date: 03/02/2006 Astrazeneca AB Warrant signed on: 3281 New Compounds SE. 15185 Sodertalje, Sweden Rec: 727/728 dt Wef: 11/02/2005 Vide PT 3281 Att: SS & Co. 22/08/2006 06/02/2006

Aqueous Gel Formulations Containing 1-(2- Filing Date: 03/02/2006 3M Innovative Properties 3M Centre, Saint Paul, Wef: 04/02/2005 Warrant signed on: 3282 Methylpropyl)-1H-Imidazo Rec: 718/719 dt Vide PT 3282 Company Minnesota 55133-3427, USA Wef: 12/07/2005 22/08/2006 [4,5-C][1,5] Aphthyridin -4- 06/02/2006 Amine

Lichtstrasse 35, 4056 Basel,, Filing Date: 07/02/2006 Wef: 11/02/2005 Combination of Organic Novartis AG Warrant signed on: 3283 Switzerland Rec: 771/772 dt Wef: 22/02/2005 Vide PT 3283 Compounds Att: SS & Co. 22/08/2006 08/02/2006 Wef: 11/04/2005

Pyridazine Derivatives and Xenon Pharmaceuticals 3650 Gilmore Way, Burnaby, Filing Date: 07/02/2006 Warrant signed on: 3284 their use as Therapeutic Inc. British Columbia , Canada V5G Rec: 774/775 dt Wef: 09/02/2005 Vide PT 3284 22/08/2006 Agents Att: SS & Co. 4W8 08/02/2006

Xenon Pharmaceuticals 3650 Gilmore Way, Burnaby, Filing Date: 07/02/2006 Warrant signed on: 3285 Combination Therapy Inc. British Columbia , Canada V5G Rec: 777/778 dt Wef: 09/02/2005 Vide PT 3285 22/08/2006 Att: SS & Co. 4W8 08/02/2006

901 Gateway Boulevard, South Filing Date: 07/02/2006 Crystalline forms of a Theravance Inc. Warrant signed on: 3286 San Francisco, CA 94080, Rec: 767/768 dt Wef: 10/03/2005 Vide PT 3286 Biphenyl Compound Att: S S& Co. 20/09/2006 USA 08/02/2006

Combination of Ca/Mg Salt Lichtstrasse 35, 4056 Basel, Filing Date: 09/02/2006 Novartis AG Warrant signed on: 3288 of Valsartan with an Switzerland Rec: 840/841 dt Wef: 14/02/2005 Vide PT 3288 Att: SS & Co. 22/08/2006 Antidiabetic Agent 13/02/2006 Process for making Lactose Utilizing Pre-Classification Glaxo Wellcome House, Filing Date: 09/02/2006 Techniques and Glaxo Group Limited Berkely Avenue, Greenford , Warrant signed on: 3289 Rec: 843/844 dt Wef: 10/02/2005 Vide PT 3289 Pharmaceutical Att: SS & Co. Middlesex UB6 0NN , Great 22/08/2006 13/02/2006 Formulations formed Britain therefrom

A method of preparing of Zentiva a.s. Nitrianska 100, Hlohovec Filikng Date:09/02/2006 Warrant signed on 3290 Wef: N/A Vide PT 3290 oxycodone Att: Mamo TCV 92027, Slovakia Rec: 834/5 dt 13/02/2006 17/12/2007

PO BOX 4000, Route 206 and Bristol-Myres Squibb Filing Date: 09/02/2006 Dihydroquinazolinones as 5 Province Line Road, Princeton, Warrant signed on: 3291 Company Rec: 832 dt 13/02/2006 Wef: 10/02/2005 Vide PT 3291 HT Modulators New Jersey 08543-4000, 22/08/2006 Att: MAMO TCV Advocates United States of America

Contrast Media For Nuclear Schering AG Filing Date: 09/02/2006 3294 Spin Tomography with Use Berlin 13342, Germany Wef: 15/02/2005 REFUSED Vide PT 3294 Att: MAMO TCV Advocates Rec: 824/5 dt 13/2/2006 of the Overhauser Effect

Pharmaceutical Agents that Filing Date: 09/02/2006 Contain Fluoroalkyl- Schering AG Warrant signed on: 3295 Berlin 13342, Germany Rec: 821/822 dt Wef: 17/02/2005 Vide PT 3295 Containing Metal Complexes Att: MAMO TCV Advocates 06/09/2006 13/02/2006 and Epothilones

Filing Date: 09/02/2006 Solid Oral Pharmaceutical Schering AG Mullerstrabe 178, Berlin 13353, Rec: 819/20 dt Warrant signed on: 3296 Wef: 15/02/2005 Vide PT 3296 Form for Contraception Att: MAMO TCV Advocates Germany 13/02/2006 22/08/2006

Filing Date: 09/02/2006 Pharmaceutical Products for Schering AG Mullerstrabe 178, Berlin 13353, Rec: 817/818 dt Warrant signed on: 3297 Wef: 15/02/2005 Vide PT 3297 Oral Contraception Att: MAMO TCV Advocates Germany 13/02/2006 22/08/2006

235 East 42nd Street, New Filing Date: 14/02/2006 Pfizer Inc. Warrant signed on: 3298 Oxyindole Derivatives York, NY 10017, United States Rec: 867/868 dt Wef: 22/02/2005 Vide PT 3298 Att: SS & Co. 06/09/2006 of America 15/02/2006

Compounds which Glaxo Wellcome House, Filing Date: 14/02/2006 potentiate Glutamate Glaxo Group Limited Berkeley Avenue, Greenford, Warrant signed on: 3299 Rec: 870/871 dt Wef: 15/02/2005 Vide PT 3299 Receptor and uses thereof Att: SS & Co. Middlesex UB6 0NN, Great 22/08/2006 15/02/2006 Wef: 26/01/2006 in Medicine Britain GlaxoSmithKline Filing Date: 15/02/2006 Rue de L' Institut 89, B-1330 Warrant signed on: 3301 Composition Biologicals SA Rec: 969/970 dt Wef: 17/02/2005 Vide PT 3301 Rixensart, Belgium 06/09/2006 Att: SS & Co. 20/02/2006

Filing Date: 15/02/2006 Astrazeneca AB Warrant signed on: 3302 Chemical Compounds SE. 15185 Sodertalje, Sweden Rec: 972/973 dt Wef: 18/02/2005 Vide PT 3302 Att: SS & Co. 06/09/2006 20/02/2006

Filing Date: 15/02/2006 One Amgen Centre Drive, Wef: 15/02/2005 Vanilloid Receptor Ligands Amgen Inc. Rec: 967/968 dt Warrant signed on: 3303 Thousand Oaks,, California Wef: 07/04/2005 Vide PT 3303 and their use in Treatments Att: Dr.M. Chetcuti Cauchi 20/02/2006 22/08/2006 91320 - 1799, USA Wef: 15/04/2005

SmithKline Beecham One Franklin Plaza, P.O BOX Filing Date: 17/02/2006 Pharmaceutical Wef: 18/02/2005 Warrant signed on: 3304 Corporation 7929, Philadelphia, PA 19101, Rec: 989/990 dt Vide PT 3304 Compositions and Methods Wef: 01/07/2005 06/09/2006 Att: SS & Co. USA 20/02/2006

Filing Date: 21/02/2006 Astrazeneca AB Warrant signed on: 3305 Amide Derivatives SE 15185 Sodertalje, Sweden Rec: 1053/1054 dt Wef: 26/02/2005 Vide PT 3305 Att: SS & Co. 06/09/2006 21/02/2006

Filing Date: 21/02/2006 Wef: 26/02/2005 Astrazeneca AB Warrant signed on: 3306 Quinazoline Derivatives SE 15185 Sodertalje, Sweden Rec:1050/1051dt Wef: 31/03/2005 Vide PT 3306 Att: SS & Co. 06/09/2006 21/02/2006 Wef: 25/11/2005 MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No

Filing Date: 21/02/2006 Pharmaceutical Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3307 Rec: 1047/1048 dt Wef: 01/03/2005 Vide PT 3307 compositions Att: SS & Co Basel, Switzerland 20/09/2006 21/02/2006

B- crystalline form of ivabradine hydrochloride, a 12, Place de la Defense Filing Date: 21/02/2006 Les Laboratoires Servier Warrant signed on 3308 process for its preparation F-92415 Courbevoie Rec: 1045/1046 dt Wef: 28/02/2005 Vide PT 3308 Att: SS & Co 06/09/2006 and pharmaceutical Cedex, France 21/02/2006 compositions containing it

Bd-crystalline form of ivabradine hydrochloride, a 12, Place de la Defense Filing Date: 21/02/2006 Les Laboratoires Servier Warrant signed on 3309 process for its preparation F-92415 Courbevoie Rec: 1043/1044 dt Wef: 28/02/2005 Vide PT 3309 Att: SS & Co 06/09/2006 and pharmaceutical Cedex, France 21/02/2006 compositions containing it

Y-crystalline form of ivabradine hydrochloride, a 12, Place de la Defense Filing Date: 21/02/2006 Les Laboratoires Servier Warrant signed on 3310 process for its preparation F-92415 Courbevoie Rec: 1041/1042 dt Wef: 28/02/2005 Vide PT 3310 Att: SS & Co 06/09/2006 and pharmaceutical Cedex, France 21/02/2006 compositions containing it

Yd- crytalline form of ivabradine hydrochloride, a 12, Place de la Defense Filing Date: 21/02/2006 Les Laboratoires Servier Warrant signed on 3311 process for its preparation F-92415 Courbevoie Rec: 1039/1040 dt Wef: 28/02/2005 Vide PT 3311 Att: SS & Co 06/09/2006 and pharmaceutical Cedex, France 21/02/2006 compositions containing it

Filing Date: 21/02/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3312 Acetylene derivatives Rec: 1036/1037 dt Wef: 22/02/2005 Vide PT 3312 Att: SS & Co Basel, Switzerland 06/09/2006 21/02/2006 Novel compounds, Isomer thereof or pharmaceutically acceptable salts thereof as 181, Haukaug-ro 2-ka, Filing Date: 21/02/2006 Amorepacific Corporation Wef: 16/03/2005 Warrant signed on 3313 vannilloid receptor Yongsan-KU, Seoul 140- Rec: 1073/1074 dt Vide PT 3313 Att: MAMO TCV Advocates Wef: 17/03/2005 04/10/2006 antagonist; and a 777, Republic of Korea 22/02/2006 pharmaceutical composition containing the same

Detection of compounds One Amgen Center Drive, Filing Date: 22/02/2006 Amgen Inc. Warrant signed on 3314 that affect therapeutic Thousand Oaks, CA 91320- Rec: 1096/1097 dt Wef: 24/02/2005 Vide PT 3314 Att: Dr M. Chetcuti Cauchi 06/09/2006 activity 1799, USA 24/02/2006

Glaxo Wellcome House, Filing Date: 23/02/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3315 Novel compounds Rec: 1102/1103 dt Wef: 25/02/2005 Vide PT 3315 Att: SS & Co Greenford, Middlesex UB6 06/09/2006 24/02/2006 ONN, Great Britian

Raheems East, Filing Date: 23/02/2006 Amorphous Lercanidipine Recordati Ireland Limited Warrant signed on 3316 Ringaskiddy, Co. Cork, Rec: 1104/1105 dt Wef: 25/02/2005 Vide PT 3316 hydrochloride Att: SS & Co 06/09/2006 Ireland 24/02/2006

Raheems East, Filing Date: 23/02/2006 Recordati Ireland Limited Warrant signed on 3317 Lercanidipine free base Ringaskiddy, Co. Cork, Rec: 1107/1108 dt Wef: 25/02/2005 Vide PT 3317 Att: SS & Co 06/09/2006 Ireland 24/02/2006

Filing Date: 23/02/2006 Aqueous gels of high Rec: 1110 /1111 dt stability based on Galderma S.A. Zugerstrasse 8, CH-6330 Warrant signed on 3318 24/02/2006 Wef: 25/02/2005 Vide PT 3318 metronidazole and methods Att: SS & Co Cham, Switzerland 06/09/2006 Claims Fee Lm40 for their preparation Rec 1112 of 24/02/2006

Wef: 23/02/2005 Wef: 01/08/2005 Wef: 30/01/2006 Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 23/02/2006 Processes for preparing Wef: 30/01/2006 Warrant signed on 3319 Industries Ltd 3190 Petah Tiqva 49131, Rec: 1099/1100 dt Vide PT 3319 sertraline Wef: 14/02/2006 06/09/2006 Att: Dr M. Chetcuti Cauchi Israel 24/02/2006 Wef: 14/02/2006 Wef: 25/01/2006 Wef: 25/01/2006

Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 24/02/2006 Wef: 24/02/2005 Crystalline forms of Warrant signed on 3320 Industries Ltd 3190 Petah Tiqva 49131, Rec: 1153/1154 dt Wef: 24/02/2005 Vide PT 3320 Linezolid intermediate 06/09/2006 Att: Dr M. Chetcuti Cauchi Israel 28/02/2006 Wef: 14/06/2005 Clopidogrel base suitable Wef: 24/02/2005 Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 24/02/2006 for pharmaceutical Wef: 07/03/2005 Warrant signed on 3321 Industries Ltd 3190 Petah Tiqva 49131, Rec: 1150/1151 dt Vide PT 3321 formulation and preparation Wef: 14/03/2005 04/10/2006 Att: Dr M. Chetcuti Cauchi Israel 28/02/2006 thereof Wef: 26/04/2005

One Amgen Center Drive, Filing Date: 24/02/2006 Epidermal growth factor Amgen Inc. Mail Stop 27-4-A, Warrant signed on 3322 Rec: 1170/1171 dt Wef: 24/02/2005 Vide PT 3322 receptor mutations Att: Dr M. Chetcuti Cauchi Thousand Oaks, CA-91320- 04/10/2006 01/05/2006 1799,California, USA

Biphenyl compounds useful 901, Gateway Boulevard, Filing Date: 28/02/2006 Theravance Inc. Warrant signed on 3323 as muscarine receptor South San Francisco, CA Rec: 1140/1141 dt Wef: 10/03/2005 Vide PT 3323 Att: SS & Co 20/09/2006 antagonists 94080, USA 28/02/2006

Use of Diosmetin 12, Place de la Defense Filing Date: 28/02/2006 Compounds in the Les Laboratoires Servier Wef: 01/03/2005 Warrant signed on 3324 F-92415 Courbevoie Rec: 1143/1144 dt Vide PT 3324 Treatment and Prevention of Att: SS & Co 20/09/2006 Cedex, France 28/02/2006 Thrombotic Pathologies

New phosphinic amino acid 12, Place de la Defense compounds, a process for Les Laboratoires Servier & F-92415 Courbevoie Filing Date: 28/02/2006 their preparation and Commissariat A L'Energie Warrant signed on 3325 Cedex, France & Rec: 1145/1146 dt Wef: 01/03/2005 Vide PT 3325 pharmaceutical Atomique (CEA) 20/09/2006 31-33 rue de la Federation, 28/02/2006 compositions containing Att: SS & Co. F-75752 Paris 15e, France them

Novel aminopyridine 2-1, Toranomon 2- Chome, Filing Date: 28/02/2006 Japan Tabacco Inc. Wef: 28/02/2005 Warrant signed on 3326 compounds having SYK Minato-ku, Tokyo 105- Rec: 1147/1148 dt Vide PT 3326 Att: SS & Co Wef: 19/01/2006 04/10/2006 inhibitory activity 8422, Japan 28/02/2006

893, North Warson Road, Filing Date: 02/03/2006 Wef: 03/03/2005 ISW Group Inc. Warrant signed on 3327 Topical gel 3 compositions St Louis, Missouri, 63141, Rec: 1217/1218 dt Wef: 13/05/2005 Vide PT 3327 Att: MAMO TCV Advocates 20/09/2006 USA 02/03/2006 Wef: 14/06/2005

Glaxo Smithkline Rue de L'institut 89, B-1330 Filing Date: 03/03/2006 Warrant signed on 3328 Vaccine Biologicals s.a Wef: 03/03/2005 Vide PT 3328 Rixensart, Belgium Rec: 1239 of 06/03/2006 20/09/2006 Att: SS & Co

Substituted N- Filing Date: 03/03/2006 sulfonylaminophenylethyl 2- Pfizer Inc. 235, East 42nd Street, New Warrant signed on 3329 Rec: 1242/1243 dt Wef: 10/03/2005 Vide PT 3329 phenoxyacetamide Att: SS & Co York, NY 10017, USA 20/09/2006 06/03/2006 compounds Euzymatic transformation of Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 03/03/2006 Warrant signed on 3330 a prostagladin (Bimatoprost) Industries Ltd 3190, Petah Tiqva 49131, Rec: 1236/1237dt Wef: 04/03/2005 Vide PT 3330 20/09/2006 intermediate Att: CCA Interserv Ltd Israel 06/03/2006

Phthalazine, Aza-and diaza- One Amgen Center Drive, Filing Date: 03/03/2006 Amgen Inc. Wef: 03/03/2005 Warrant signed on 3331 phthalazine compounds and Thousand Oaks, CA 91320- Rec: 1233/1234 dt Vide PT 3331 Att: CCA Interserv Ltd Wef: 02/03/2006 20/09/2006 methods of use 1799, USA 06/03/2006

A new process for the Via della Carboneria preparation of 17B-N- (2,5 S.N.I.F.F Italia Spa Filing Date: 07/03/2006 30/32 - Localita' Warrant signed on 3332 bis (Trifluoromethyl) - Att: Sterling Chemicals Malta Rec: 1331/1332 dt Wef: N/A Vide PT 3332 Solomeo-Corciano 17/12/2007 Phenyl) Carboxyl - 4- AZA -5 Ltd 08/03/2006 Perugia- Italy X Androst -1-1 EN -3-One

Via della Carboneria S.N.I.F.F Italia Spa Filing Date: 07/03/2006 A process for the 30/32 - Localita' 3333 Att: Sterling Chemicals Malta Rec: 1329/1330 dt Wef: N/A REFUSED Vide PT 3333 preparation of drospirenone Solomeo-Corciano Ltd 08/03/2006 Perugia- Italy

Filing Date: 07/03/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3334 Novel compounds Rec: 1323/1324 dt Wef: 16/03/2005 Vide PT 3334 Att: SS & Co Sweden 04/10/2006 08/03/2006

Anti-proliferative combination therapy using Fraunhofersti 20, Filing Date: 08/03/2006 Wef: 11/03/2005 GPC Biotech AG Warrant signed on 3335 certain platinum-based Martinsried 82152, Rec: 1365/1366 dt Wef: 21/03/2005 Vide PT 3335 Att: MAMO TCV Advocates 20/09/2006 chemotherapeutic agents Germany 08/03/2006 Wef: 10/11/2005 and taxanes

N-(2-chloro-6-methylphenyl)- 2- [[6-[4-(2-hydroxyethyl)-1- PO Box 4000, Route 206 Bristol-myers Squibb Filing Date: 08/03/2006 piperazinyl]-2-methyl-4- and Province Line Rd, Wef: 15/03/2005 Warrant signed on 3336 Company Rec: 1368/1369 dt Vide PT 3336 pyrimidinyl] amino]-5- Princeton, New Jersey Wef: 20/10/2005 20/09/2006 Att: MAMO TCV Advocates 08/03/2006 thiazolecarbosamides 68543-4000, USA metabolites

Wef: 08/03/2005 Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 08/03/2006 Wef: 21/03/2005 Amorphous tegaserod Warrant signed on 3337 Industries Ltd 3190, Petah Tiqva 49131, Rec: 1396/1397 dt Wef: 06/10/2005 Vide PT 3337 maleate 20/09/2006 Att: CCA Interserv Ltd Israel 13/03/2006 Wef: 10/01/2006 Wef: 14/02/2006

Zone Industrielle de Filing Date: 08/03/2006 Ares Trading SA Warrant signed on 3338 Lipocalin protein l'Ouriettaz, CH-1170 Rec: 1393/1394 dt Wef: 08/03/2005 Vide PT 3338 Att: CCA Interserv 04/10/2006 Aubonne, Switzerland 13/03/2006 Certain substituted amides, Filing Date: 10/03/2006 CGI Pharmaceuticals Inc. 36 East Industrial Road, Warrant signed on 3339 method of making and Rec: 1436/1437 dt Wef: 10/03/2005 Vide PT 3339 Att: Bezzina & Mifsud Branford, CT 06405, USA 20/09/2006 method of use thereof 14/03/2006

Filing Date: 14/03/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3340 Novel compounds Rec: 1462/1463 dt Wef: 22/03/2005 Vide PT 3340 Att: SS & Co Sweden 04/10/2006 14/03/2006

Eastern Point Road, Filing Date: 14/03/2006 Substituted Aryl 1,4- Pfizer Products Inc. Warrant signed on 3341 Groton, Connecticut 06340, Rec: 1459/1460 dt Wef: 17/03/2005 Vide PT 3341 pyrazine derivatives Att: SS & Co 04/10/2006 USA 14/03/2006

Substituted Eastern Point Road, Filing Date: 14/03/2006 Wef: 17/03/2005 Pfizer Products Inc. Warrant signed on 3342 sulfonylaminoarylmethylcycl Groton, Connecticut 06340, Rec: 1456/1457 dt Wef: 15/07/2005 Vide PT 3342 Att: SS & Co 04/10/2006 oprofanecarboxamide USA 14/03/2006 Wef: 04/11/2005

Wef: 12/10/2005 Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 14/03/2006 Pure duloxetine Wef: 14/11/2005 Warrant signed on 3343 Industries Ltd 3190, Petah Tiqva 49131, Rec: 1515/1516 dt Vide PT 3343 hydrochlorine Wef: 14/03/2005 20/09/2006 Att: CCA Interserv Ltd Israel 16/03/2006 Wef: 14/02/2006

Wef: 12/10/2005 Teva Pharmaceutical 5, Basel Street, P.O. Box Filing Date: 14/03/2006 Pure duloxetine Wef: 14/11/2005 Warrant signed on 3344 Industries Ltd 3190, Petah Tiqva 49131, Rec: 1519/1520 dt Vide PT 3344 hydrochlorine Wef: 14/03/2005 20/09/2006 Att: CCA Interserv Ltd Israel 16/03/2006 Wef: 14/02/2006

Novel compounds, isomer thereof , or pharmaceutically 181, Hankang-ro 2-ka, acceptable salts thereof as Filing Date: 15/03/2006 Amorepacific Corporation Yongsan-KU, Seoul 140- Wef: 19/03/2005 Warrant signed on 3346 vanilloid receptor antagonist Rec: 1473/1474 dt Vide PT 3346 Att: MAMO TCV Advocates 777, Republic of Korea Wef: 21/03/2005 04/10/2006 and pharmaceutical 15/03/2006 compositions containing the same

Filing Date: 17/03/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3347 Organic compounds Rec: 1557/1558 dt Wef: 23/03/2005 Vide PT 3347 Att: SS & Co Basel, Switzerland 04/10/2006 17/03/2006

Filing Date: 17/03/2006 Pharmaceutical Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3348 Rec: 1554/1555 dt Wef: 24/03/2005 Vide PT 3348 compositions Att: SS & Co Basel, Switzerland 04/10/2006 17/03/2006 Novel compounds, isomer thereof, of pharmaceutically acceptable salts thereof as 181, Hankang-ro 2-ka, Filing Date: 17/03/2006 vanilloid receptor Amorepacific Corporation Yongsan-KU, Seoul 140- Wef: 19/03/2005 Warrant signed on 3349 Rec: 1564/1566 dt Vide PT 3349 antagonist; and Att: MAMO TCV Advocates 777, Republic of Korea Wef: 21/03/2005 04/10/2006 17/03/2006 pharmaceutical compositions containing the same

One Amgen Center Drive, Filing Date: 17/03/2006 Methods of decreasing Amgen Inc. Warrant signed on 3350 Thousand Oaks, CA 91320- Rec: 1574 /1575 dt Wef: 17/03/2005 Vide PT 3350 calcifications Att: CCA Interserv Ltd 04/10/2006 1799, USA 20/03/2006

16711 Trans-Canada, Filing Date: 17/03/2006 Novel pharmaceutical Merck Frosst Canada Ltd Warrant signed on 3351 Highway, Kirkland, Quebec Rec: 1571/1572 dt Wef: 23/03/2005 Vide PT 3351 compounds Att: CCA Interserv Ltd 04/10/2006 H9H 3H, Canada 20/03/2006

Via della Carboneria A process for the S.N.I.F.F Italia Spa Filing Date: 20/03/2006 30/32 - Localita' Warrant signed on 3352 preparation of mometasone Att: Sterling Chemicals Malta Rec: 1836/7/8 dt Wef: N/A Vide PT 3352 Solomeo-Corciano 17/12/2007 furoate Ltd 30/03/2006 Perugia- Italy

Glaxo Smithkline Filing Date: 21/03/2006 Rue de L'institut 89, B-1330 Warrant signed on 3353 Novel use Biologicals s.a Rec: 1609/1610 dt Wef: 25/03/2005 Vide PT 3353 Rixensart, Belgium 04/10/2006 Att: SS & Co 21/03/2006

Glaxo Smithkline Filing Date: 21/3/2006 Rue de L'institut 89, B-1330 Warrant signed on 3354 Novel compositions Biologicals s.a Rec: 1613/4 dt Wef: 25/03/2005 Vide PT 3354 Rixensart, Belgium 04/10/2006 Att: SS & Co 21/03/2006

Glaxo Smithkline Filing Date: 21/03/2006 Rue de L'institut 89, B-1330 Warrant signed on 3355 Composition Biologicals s.a Rec: 1615/1616 dt Wef: 23/03/2005 Vide PT 3355 Rixensart, Belgium 04/10/2006 Att: SS & Co 21/03/2006

5H- Benzocycloheptene Schering Filing Date: 21/03/2006 derivatives, process for their Mullerstrabe 178, Berlin Warrant signed on 3356 Aktiengesellschaft Rec: 1630/1631 dt Wef: 22/03/2005 Vide PT 3356 production and their use as 13353, Germany 04/10/2006 Att: MAMO TCV Advocates 21/03/2006 anti-inflammatory agents

Tetrahydronaphthalene Schering Filing Date: 21/03/2006 derivatives, process for their Mullerstrabe 178, Berlin Warrant signed on 3357 Aktiengesellschaft Rec: 1627 /1628 dt Wef: 22/03/2005 Vide PT 3357 production and their use as 13353, Germany 04/10/2006 Att: MAMO TCV Advocates 21/03/2006 anti-inflammatory agents One Amgen Center Drive, Filing Date: 22/03/2006 Combinations for the Amgen Inc. Warrant signed on 3358 Thousand Oaks, CA 91320- Rec: 1651/1652 dt Wef: 22/03/2005 Vide PT 3358 treatment of cancer Att: Mr J. Mifsud 04/10/2006 1799, USA 23/03/2006

Glaxo Wellcome House, Filing Date: 23/03/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3360 Novel compounds Rec: 1672/1673 dt Wef: 25/03/2005 Vide PT 3360 Att: SS & Co Greenford, Middlesex UB6 04/10/2006 23/03/2006 ONN, Great Britian

Glaxo Wellcome House, Wef: 24/03/2005 Filing Date: 23/03/2006 Glaxo Group Limited Berkeley Avenue, Wef: 07/04/2005 Warrant signed on 3361 Novel compounds Rec: 1688/1689 dt Vide PT 3361 Att: SS & Co Greenford, Middlesex UB6 Wef: 24/06/2005 04/10/2006 24/03/2006 ONN, Great Britian Wef: 19/10/2005

Glaxo Wellcome House, Filing Date: 23/03/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3362 Novel Compound Rec: 169/1692 dt Wef: 25/03/2005 Vide PT 3362 Att: SS & Co Greenford, Middlesex UB6 04/10/2006 24/03/2006 ONN, Great Britian

Paseo de la Castellna,141, Filing Date: 23/03/2006 Novel substituted Schwarz Pharma S.L. Warrant signed on 3363 Planta 15, Rec: 1675/1676 dt Wef: N/A Vide PT 3363 arylpiperazine derivatives Att: CCA Interserv 17/12/2007 E-28046 Madrid, Spain 23/03/2006

Tetrahydro- pyridoazepin-8- Warner- Lambert Company 201, Tabor Road, Morris Filing Date: 28/03/2006 ones and related Warrant signed on 3364 LLC Plains, New Jersey 07950, Rec: 1761/1762 dt Wef: 01/04/2005 Vide PT 3364 compounds for the 18/10/2006 Att: SS & Co USA 28/03/2006 treatment of schizophrenia

Cyclopentapyridine and Eastern Point Road, Filing Date: 28/03/2006 Pfizer Products Inc. Wef: 31/03/2005 Warrant signed on 3365 tetrahydroquinoline Groton, Connecticut 06340, Rec: 1788/1789 dt Vide PT 3365 Att: SS & Co Wef: 26/01/2006 04/10/2006 derivatives USA 28/03/2006

Penciclovir For The Filing Date: 28/03/2006 Treatment of Recurrent Novartis AG Lichtstrasse 35, 4056 3366 Rec: 1756/1757 dt Wef: 30/03/2005 WITHDRAWN Vide PT 3366 Genital Herpes With a One- Att: SS & Co Basel, Switzerland 28/03/2006 Day Application

Indanyl- piperazine compounds, or process for 12, Place de la Defense Filing Date: 28/03/2006 their preparation and Les Laboratoires Servier Warrant signed on 3367 F-92415 Courbevoie Rec: 1784/1785 dt Wef: 30/03/2005 Vide PT 3367 pharmaceutical Att: SS & Co 04/10/2006 Cedex, France 28/03/2006 compositions containing them Penciclovir for the treatment Filing Date: 28/03/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3368 of recurrent herpes labialis Rec: 1751/1752 dt Wef: 30/03/2005 Vide PT 3368 Att: SS & Co Basel, Switzerland 04/10/2006 using a one-day treatment 28/03/2006

Epidermal growth factor One Amgen Center Drive, Filing Date: 30/03/2006 Amgen Inc. Warrant signed on 3369 receptor gene copy number Thousand Oaks, CA 91320- Rec: 1781/1782 dt Wef: 01/04/2005 Vide PT 3369 Att: J. Mifsud 18/10/2006 field 1799, USA 30/03/2006

Wef: 30/03/2005 Fruebjergrej 3, Filing Date: 30/03/2006 Treatment of dermatological Astion Development A/S Wef: 30/03/2005 Warrant signed on 3370 Copenhagen, DK-2100, Rec: 1790/1791 dt Vide PT 3370 diseases and pruritus Att: MAMO TCV Advocates Wef: 27/06/2005 04/10/2006 Denmark 30/03/2006 Wef: 27/06/2005

LTS Lohmann Therapie- Andernach, D-56626 Filing Date: 30/03/2006 Wafer comprising steroid Systeme AG & Schering Warrant signed on 3371 Germany & Berlin, D- Rec: 1793/1794 dt Wef: 31/03/2005 Vide PT 3371 hormones AG 18/10/2006 13342, Germany 30/03/2006 Att: MAMO TCV Advocates

Novel tyrosinase inhibitors, process for the preparation Galderma Research & 635, Route des Lucioles, Filing Date: 30/03/2006 Warrant signed on 3372 thereof and use thereof in Development, S.N.C. BP87 06902 Sophia, Rec: 1857/1858 dt Wef: 01/04/2005 Vide PT 3372 18/10/2006 human medicine and also in Att: SS & Co Antipolis Cedex, France 03/04/2006 cosmetics

Novel tyrosinase inhibitors Galderma Research & 635, Route des Lucioles, Filing Date: 30/03/2006 and use thereof in human Warrant signed on 3373 Development, S.N.C. BP87 06902 Sophia, Rec: 1860/1861 dt Wef: 01/04/2005 Vide PT 3373 medicine and also in 18/10/2006 Att: SS & Co Antipolis Cedex, France 03/04/2006 cosmetics

Glaxo Wellcome House, Process for preparing pyrido Filing Date: 30/03/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3374 [2,3-d] pyrimidine -7- one Rec: 1863/1864 dt Wef: N/A Vide PT 3374 Att: SS & Co Greenford, Middlesex UB6 17/12/2007 derivatives 03/04/2006 ONN, Great Britian

Method for selectively Amgen Inc. One Amgen Center Drive, Filing Date: 30/03/2006 Warrant signed on 3375 blocking hemoglobin RNA Att: Chetcuti Cauchi Thousand Oaks, CA 91320- Rec: 1854/1855 dt Wef: 31/03/2005 Vide PT 3375 04/10/2006 amplification Advocates 1799, USA 03/04/2006

Marie-Therese Triganza Filing Date: 30/03/2006 RL9 Ricasoli Industrial Warrant signed on 3376 Bio-ethonol Production SKAT Ltd. Rec: P585568 dt Wef: N/A Vide PT 3376 Estate, Kalkara, Malta 17/12/2007 Att: Dr David Gonzi 30/03/2006

Crystalline form of a 901 Gateway Boulevard, Filing Date: 04/04/2006 Theravance Inc. Warrant signed on 3377 quinolinone carboxamide South San Fransisco, CA Rec: 1905/1906 dt Wef: 06/04/2005 Vide PT 3377 Att: SS & Co 18/10/2006 compounds 94080, USA 04/04/2006 Bicyclic [3.1.0] heteroaryl Eastern Point Road, Filing Date: 04/04/2006 Pfizer Products Inc. Warrant signed on 3378 amides as type 1 glycine Groton, Connecticut 06340, Rec: 1908/1909 dt Wef: 08/04/2005 Vide PT 3378 Att: SS & Co 08/10/2006 transport inhibitors USA 04/04/2006

Novel 5-substituted 7-amino Filing Date: 04/04/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3379 [1,3] thiazolo [4,5-D] Rec: 1911 /1912 dt Wef: 06/04/2005 Vide PT 3379 Att: SS & Co Sweden 18/10/2006 pyrimidine derivatives 04/04/2006

Novel 5,7- disubstituted [1,3] Filing Date: 04/04/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3380 thiazolo [4,5 D] pyrimidin-2 Rec: 1914/1915 dt Wef: 06/04/2005 Vide PT 3380 Att: SS & Co Sweden 18/10/2006 (3H)- one derivatives 04/04/2006

Pharmacia & Upjohn 7000 Portage Road, Filing Date: 04/04/2006 An oxindole oxazolidinone Wef: 06/04/2005 Warrant signed on 3381 Company LLC Kalamazoo, Hidregan Rec: 1917/1918 dt Vide PT 3381 as antibacterial agent Wef: 24/05/2005 18/10/2006 Att: SS & Co 49001-0199, USA 04/04/2006

7-Fluoro-1, 3-dihdro-indol-2- Pharmacia & Upjohn 7000 Portage Road, Filing Date: 04/04/2006 Wef: 06/04/2005 Warrant signed on 3382 one oxazolidinones as Company LLC Kalamazoo, Hidregan Rec: 1920/1921dt Vide PT 3382 Wef: 24/05/2005 18/10/2006 antibacterial agents Att: SS & Co 49001-0199, USA 04/04/2006

Filing Date: 04/04/2006 Substituted heterocycles AstraZeneca AB SE-151 85 Sodertalje, Wef: 06/04/2005 Warrant signed on 3383 Rec: 1923/1924 dt Vide PT 3383 and the uses thereof Att: SS & Co Sweden Wef: 21/11/2005 18/10/2006 04/04/2006

Compounds having activity Smithkline Beecham One Franklin Plaza, PO Filing Date: 04/04/2006 Warrant signed on 3384 at NK 3 receptor and uses Corporation Box 7929, Philadelphia, PA Rec: 1926/1927 dt Wef: N/A Vide PT 3384 17/12/2007 thereof in medicine Att: SS & Co 19101, USA 04/04/2006

Stable atomoxetine Strada, Statale Briantea hydrochloride, a process for TEVA Pharmaceutical Fine Filing Date: 05/04/2006 Wef: 05/04/2005 KM36, No83, Warrant signed on 3385 the preparation thereof, and Chemicals S.R.L. Rec: 1962/1963 dt Wef: 31/05/2005 Vide PT 3385 23892 Bulciago (LC) 18/10/2006 an analytical control of its Att: Dr MJ. Chetcuti Cauchi 06/04/2006 Wef: 07/06/2005 Italy stability

Filing Date: 06/04/2006 Crystal form of asenapine N.V. Organon Kloosterstraat 6, NL-5349 Wef: 07/04/2005 Warrant signed on 3386 Rec: 1974/1975 dt Vide PT 3386 maleate Att: SS & Co AB Oss, The Netherlands Wef: 14/04/2005 18/10/2006 06/04/2006

Filing Date: 06/04/2006 Novel compounds of amino Pfizer Inc. 235, East 42nd Street, New Wef: 07/04/2005 Warrant signed on 3387 Rec: 1977/1978 dt Vide PT 3387 sulfonyl derivatives Att: SS & Co York, NY 10017, USA Wef: 10/02/2006 18/10/2006 06/04/2006 Filing Date: 06/04/2006 Ghrelin binding Nucleic Noxxon Pharma AG Max-Dolirn St, 8-10, D- Warrant signed on 3388 Rec: 1980/1981 dt Wef: 08/04/2005 Vide PT 3388 Acids Att: SS & Co 10589 Berlin, Germany 18/10/2006 06/04/2006

Pyrrolo [2,3-d]Imidazoles for Filing Date: 06/04/2006 OSI Pharmaceuticals, Inc 41, Pinelawn Road, Warrant signed on 3389 the treatment of Rec: 1970/1971 dt Wef: N/A Vide PT 3389 Att: SS & Co Melville, NY11747, USA 17/12/2007 Hyperproliferative disorders 06/04/2006

Filing Date: 07/04/2006 Method for the Manufacture Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3390 Rec: 2006/7 dt Wef: 14/04/2005 Vide PT 3390 of Organic Compounds Att: SS & Co Basel, Switzerland 18/10/2006 07/04/2006

Filing Date: 07/04/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3391 1H- Quinazoline - 2,4- diones Rec: 2009/2010 dt Wef: 11/04/2005 Vide PT 3391 Att: SS & Co Basel, Switzerland 18/10/2006 07/04/2006

Piperazine compounds, a process for their preparation 12 Place de la Defense Filing Date: 07/04/2006 Les Laboratoires Servier Warrant signed on 3392 and pharmaceutical F-92415 Coubevoie Rec: 2012/2013 dt Wef: 08/04/2005 Vide PT 3392 Att: SS & Co 18/10/2006 compositions containing Cedex, France 07/04/2006 them

New Method for the Preparation of 6-[3-(1- Galderma Research & Les Templiers, 2400 Route Filing Date: 07/04/2006 Warrant signed on 3393 adamantyl)-4- Development des Colles, 06410 Biot, Rec: 2015/6 dt Wef 08/04/2005 Vide PT 3393 18/10/2006 methoxyphenyl]-2-naphthoic Att: SS & Co France 07/04/2006 acid

Sulfoxinine - macrocrocycle compounds and salts thereof, pharmaceutical Filing Date: 07/04/2006 Shering AG Wef: 08/04/2005 Warrant signed on 3394 compositions comprising Berlin 13342, Germany Rec: 2041/2042 dt Vide PT 3394 Att: MAMO TCV Advocates Wef: 13/04/2005 18/10/2006 said compounds, method of 07/04/2006 preparing same and uses of same

Wef: 08/04/2005 Filing Date: 07/04/2006 Lonza AG Muenchensteinerstrasse Wef: 09/05/2005 Warrant signed on 3395 Method of Peptide Synthesis Rec: 2083/2084 dt Vide PT 3395 Att: CCA InterServ Ltd 38, 4002 Basel, Switzerland Wef: 18/07/2005 18/10/2006 10/04/2006 Yeda Research and Weizmann Institute of Filing Date: 10/04/2006 Chimeric proteins and their Warrant signed on 3396 Development Co Ltd Science, PO Box 95, Rec: 2086/2087 dt Wef: 11/04/2005 Vide PT 3396 use 18/10/2006 Att: CCA Interserv Ltd Rehovot, 76100, Israel 10/04/2006

Use of vascular endothelial growth factor receptor Filing Date: 11/04/2006 inhibitors for the treatment Novartis AG Lichtstrasse 35, 4056 3397 Rec: 2151/2152 dt Wef: 13/04/2005 Warrant signed on Vide PT 3397 of gastrointestinal, Att: SS & Co Basel, Switzerland 17/04/2006 18/10/2006 genitourinary, lymphoid and pulmonary cancers

Eisai R&D Management Filing Date: 11/04/2006 6-10 Koishikawa, 4-Chome, Wef: 15/04/2005 Warrant signed on 3398 Benzimidazole compound Co. Ltd Rec: 2154/2155 dt Vide PT 3398 Bunkyo-Ku, Tokyo, Japan Wef: 29/04/2005 18/10/2006 Att: SS & Co 17/04/2006

Filing Date: 11/04/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3399 Organic compounds Rec: 2157/2158 dt Wef: 14/04/2005 Vide PT 3399 Att: SS & Co Basel, Switzerland 18/10/2006 17/04/2006

Filing Date: 11/04/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3401 Combination product Rec: 2163/2164 dt Wef: 18/04/2005 Vide PT 3401 Att: SS & Co Sweden 02/11/2006 17/04/2006

Fruebjergrej 3, Filing Date: 12/04/2006 Treatment of connective Astion Development A/S Warrant signed on 3402 Copenhagen, DK-2100, Rec: 2140/2141 dt Wef: 13/04/2005 Vide PT 3402 tissue diseases of the skin Att: MAMO TCV Advocates 18/10/2006 Denmark 17/04/2006

Tetrahydronaphthalene Schering Filing Date: 12/04/2006 derivatives, process for their Mullerstrabe 178, Berlin Warrant signed on 3403 Aktiengesellschaft Rec: 2143/2144 dt Wef: 14/04/2005 Vide PT 3403 production and their use as 13353, Germany 18/10/2006 Att: MAMO TCV Advocates 17/04/2006 anti-inflammatory agents

Tetahydronaphtalin derivatives, verfahren zu Schering Filing Date: 12/04/2006 Mullerstrabe 178, Berlin Warrant signed on 3404 ihrer herstelling and ihre Aktiengesellschaft Rec: 2148/2149 dt Wef: 14/04/2005 Vide PT 3404 13353, Germany 18/10/2006 verwending ais Att: MAMO TCV Advocates 17/04/2006 entzundungshemmer

Acylamino bicyclic Eastern Point Road, Filing Date: 12/04/2006 Pfizer Products Inc. Warrant signed on 3405 heteroaromatic compounds Groton, Connecticut Rec: 2126/2127 dt Wef: 20/04/2005 Vide PT 3405 Att: SS & Co 02/11/2006 and uses thereof 06340, USA 17/04/2006 Filing Date: 12/04/2006 Phenylacetamides suitable Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3406 Rec: 2129/2130 dt Wef: 14/04/2005 Vide PT 3406 as protein kinase inhibitors Att: SS & Co Basel, Switzerland 18/10/2006 17/04/2006

Sardinia House, Sardinia Cancer Research Street, London, WC2A Wef: 15/04/2005 Technology Limited & 3NL, United Kingdom & Filing Date: 12/04/2006 Wef: 15/04/2005 Warrant signed on 3408 2NA-PK inhibitors Kudos Pharmaceuticals 327 Cambridge Science Rec: 2135/2137 dt Wef: 18/04/2005 Vide PT 3408 18/10/2006 Limited Park, Milton Road, 17/04/2006 Wef: 01/07/2005 Att: SS & Co Cambridge, CB4 0WG, Wef: 20/09/2005 United Kingdom MT PT Patent Title Applicant Name Applicant Address MT Applic Date Priority Date Status Abstract No PO BOX 4000, Route 206 Inhibitors of 11-Beta Bristol - Myers Squibb and Province Line Road, Filing Date: 13/04/2006 Warrant signed on: 3409 Hydroxysteroid Company Princeton, New Jersey Rec: 2122/2123 dt Wef: 14/04/2005 Vide PT 3409 18/10/2006 Dehydrogenase Type 1 Att: MAMO TCV Advocates 08543-4000, United States 17/04/2006 of America

Process for preparing salts of 4-[C5- [cyclopropylamino) PO BOX 4000, Route 206 carbonyl]-2- Bristol - Myers Squibb and Province Line Road, Filing Date: 13/04/2006 methylphenyl] amino]-5- Warrant signed on: 3410 Company Princeton, New Jersey Rec: 2119/2120 dt Wef: 18/04/2005 Vide PT 3410 methyl -N- 02/11/2006 Att: MAMO TCV Advocates 08543-4000, United States 17/04/2006 propylpyrrolo[2,f][1,2,4] of America triazine -6-carboxamide and novel, stable forms produced therein

PO BOX 4000, Route 206 Combinations, Methods Bristol - Myers Squibb and Province Line Road, Filing Date: 13/04/2006 Wef: 13/04/2005 Warrant signed on: 3411 and Compositions for Company Princeton, New Jersey Rec: 2114/2115 dt Wef: 08/12/2005 Vide PT 3411 18/10/2006 Treating Cancer Att: MAMO TCV Advocates 08543-4000, United States 17/04/2006 Wef: 12/04/2006 of America

Synthesis and Fructuos Gelabert, 6-8, Filing Date: 13/04/2006 Preparations of Medichem SA Wef: 15/04/2005 Warrant signed 3412 08970 Sant Joan Despi, Rec: 2110/2111 dt Vide PT 3412 polymorphs of crystalline Att: SS & Co. Wef: 14/11/2005 18/10/2006 Barcelona, Spain 17/04/2006 aripiprazole.

Filing Date: 13/04/2006 Vamilloid Receptor One Amgen Centre Drive, Amgen Inc. Rec: 2108/2109 dt Warrant signed on: 3413 Ligands and their Use in Thousand Oaks, California Wef: 15/04/2005 Vide PT 3413 Att: Dr. M. Chetcuti Cauchi 17/04/2006 18/10/2006 Treatments 91320 - 1799, USA

Fluorinated pyridine n- oxide thrombin Janssen Pharmaceutica Filing Date: 18/04/2006 modulator and Process Turnhoutseweg 30, B-2340 Wef: 20/04/2005 Warrant signed on: 3414 N.V Rec: 2233/2234 dt Vide PT 3414 for N- Oxidation of Beerse, Belgium Wef: 21/03/2006 02/11/2006 Att: EMD Advocates 18/04/2006 Nitrogen Containing Heteroaryls

Filing Date: 18/04/2006 AstraZeneca AB SE. 15185 Sodertalje, Wef: 20/04/2005 Warrant signed on: 3415 Novel Compounds Rec: 2264/2265 dt Vide PT 3415 Att: SS & Co. Sweden Wef: 07/12/2005 02/11/2006 18/04/2006 Use of Agomelatine in Obtaining Medicaments 12. Place De La Defense, F- Filing Date: 18/04/2006 Les Laboratoires Servier Warrant signed on: 3416 Intended for the 92415 Courbevoie Cedex, Rec: 2277/2278 dt Wef: 20/04/2005 Vide PT 3416 Att: SS & Co. 02/11/2006 Treatment of Bipolar France 18/04/2006 Disorders

Filing Date: 18/04/2006 Pfizer Limited Ramsgate Road, Sandwich , Rec: 2275/2276 dt Warrant signed on: 3417 Amino Acid Derivatives Wef: 28/04/2005 Vide PT 3417 Att: SS & Co. Kent CT 13 9NJ, England 18/04/2006 02/11/2006

235 East 42nd , Street New Filing Date: 18/04/2006 Pfizer Inc. Warrant signed on: 3418 P-Cadherin Antibodies York, New York 10017, USA Rec: 2272/2273 dt Wef: 26/04/2005 Vide PT 3418 Att: SS & Co. 02/11/2006 18/04/2006

Smithkline Beecham Filing Date: 18/04/2006 Pharmaceutical Currabinny, Carrigaline, Co. Warrant signed on: 3419 (Cork) Limited Rec: 2270/2271 dt Wef: 19/04/2005 Vide PT 3419 Composition Cork , Ireland 02/11/2006 Att: SS & Co. 18/04/2006

Filing Date: 18/04/2006 Compounds Useful in Pfizer Limited Ramsgate Road, Sandwich , Warrant signed on: 3420 Rec: 2267/2268 dt Wef: 20/04/2005 Vide PT 3420 Therapy Att: SS & Co. Kent CT 13 9NJ, England 02/11/2006 18/04/2006

Substituted Heterocyclic One Amgen Centre Drive, Filing Date: 18/04/2006 Amgen Inc. Wef: 19/04/2005 Warrant signed on: 3421 Compounds and Thousand Oaks, California Rec: 2260/2261 dt Vide PT 3421 Att: CCA Interserv Ltd. Wef: 06/04/2006 02/11/2006 Methods of Use 91320 - 1799, USA 18/04/2006

Smithkline Beecham One Franklin Plaza, PO Box Filing Date: 19/04/2006 Wef: 20/04/2005 Warrant signed on: 3422 Inhibitors of Akt Activity Corporation 7929, Philadelphia, PA Rec: 2338/2339 dt Vide PT 3422 02/11/2006 Att: SS & Co. 19101, USA 20/04/2006

Use of Azithromycin for 12, Rue Louis Bleriot, Zone Filing Date: 20/04/2006 the Manufacturing of a Laboratoires Thee Industrielle du Brezet, F- Rec: 2363/2364 dt Warrant signed on: 3423 Wef: 22/04/2005 Vide PT 3423 Medicament for Treating Att: Busuttil & Busuttil 63100 Clermont, Ferrand, 20/04/2006 02/11/2006 Occular Infections France

High Affinity Fully Human Monoclonal Antibodies Filing Date: 20/04/2006 Amgen Fremont Inc. 6701 Kaiser Drive, Fremont, Warrant signed on: 3424 to Interleukin -8 and Rec: 2465/2466 dt Wef: 20/04/2005 Vide PT 3424 Att: SS & Co. California 94555, USA 02/11/2006 Epitopes for Such 24/04/2006 Antibodies Filing Date: 21/04/2006 Novartis AG Lichtstrasse 35, 4056 Basel, Rec: 2422/2423 dt Warrant signed on: 3425 Acetylene Derivatives Wef: 25/04/2005 Vide PT 3425 Att: SS & Co. Switzerland 21/04/2006 02/11/2006

Process for Preparing Fructuós Gelabert, 6-8, Filing Date: 21/04/2006 Medichem S.A. Wef: 21/04/2005 Warrant signed on: 3427 Quetiapine and 08970 Saint Joan Despi, Rec: 2471/2 dt Vide PT 3427 Att: SS & Co. Wef: 28/10/2005 02/11/2006 Quetiapine Fumarate Barcelona, Spain 24/04/2006

235 East 42nd Street New Pfizer Inc. & Amgen York, New York 10017, NY, Filing Date: 24/04/2006 Warrant signed on: 3428 Antibodies to Myostatin Fremont Inc. USA & 6701 Kaiser Drive, Rec: 2461/2462 dt Wef: 25/04/2005 Vide PT 3428 02/11/2006 Att: SS & Co. Fremont, California 94555, 24/04/2006 USA

A process for the Merck Sharp & Dohme Hertford Road, Hoddesdon, Filing Date: 24/04/2006 preparation of Wef: 28/04/2005 Warrant signed on: 3429 Limited Hertfordshire EN11 9BU, Rec: 2596/7 dt Vide PT 3429 tetrazolyltetrahydrocyclo Wef: 29/04/2005 02/11/2006 Att: CC Advocates U.K. 26/04/2006 pentapyrazoles

Alantes Pharmaceuticals Filing Date: 24/04/2006 Dipeptidyl peptidase - IV 840 Memorial Drive, Warrant signed on: 3430 Inc. Rec: 2593/2594 dt Wef: 22/04/2005 Vide PT 3430 Inhibitors Cambridge, MA 02139, USA 02/11/2006 Att: CCA Interserv Ltd. 24/04/2006

One Amgen Centre Drive, Filing Date: 24/04/2006 Toxin Peptide Amgen Inc. Wef: 12/04/2005 Warrant signed on: 3431 Thousand Oaks, California Rec: 2590/2591 dt Vide PT 3431 Therapeutic Agents Att: CCA Interserv Ltd. Wef: 17/04/2006 02/11/2006 91320 - 1799, USA 26/04/2006

GlaxoSmithKline Filing Date: 25/04/2006 Wef: 26/04/2005 Rue de L' institut 89, B-1330 Warrant signed on: 3432 Vaccine Biologicals S.A Rec: 2633/2634 dt Wef: 14/06/2005 Vide PT 3432 Rixensart, Belgium 02/11/2006 Att: SS & Co. 26/04/2006 Wef: 16/12/2005

GlaxoSmithKline Filing Date: 25/04/2006 Wef: 26/04/2005 Rue de L' institut 89, B-1330 Warrant signed on: 3433 Vaccine Biologicals S.A Rec: 2636/2637 dt Wef: 05/05/2005 Vide PT 3433 Rixensart, Belgium 02/11/2006 Att: SS & Co. 26/04/2006 Wef: 14/06/2005

Glaxo Wellcome House, Filing Date: 25/04/2006 Glaxo Group Ltd Berkeley Avenue, Greenford, Warrant signed on 3434 Novel device Rec: 2640/1 dt Wef: 25/04/2005 Vide PT 3434 Att: SS & Co Middlesex UB 6 ONN, Great 02/11/2006 26/04/2006 Britian Vonilloid receptor One Amgen Centre Drive, Filing Date: 25/04/2006 Amgen Inc. Warrant signed on 3435 ligands and their use in Thousand Oaks, California Rec: 2588/9 dt Wef: 25/04/2005 Vide PT 3435 Att: CCA Interserv Ltd. 02/11/2006 treatments 91320 - 1799, USA 26/04/2006

Peptide sustained One Amgen Centre Drive, Filing Date: 25/04/2006 Amgen Inc. Warrant signed 3436 release compositions Thousand Oaks, California Rec: 2585/6 dt Wef: 25/04/2005 Vide PT 3436 Att: CCA Interserv Ltd. 02/11/2006 and uses thereof 91320 - 1799, USA 26/04/2006

Urea derivatives, Filing Date: 26/04/2006 methods for their Galapagos SAS 102 Route de Noisy, F- Warrant signed on 3437 Rec: 2628/9 dt Wef: 29/04/2005 Vide PT 3437 manufacture and uses Att: SS & Co 92230 Romainville, France 02/11/2006 20/04/2006 thereof

2200 North Commerce, Filing Date: 26/04/2006 KOS Life Sciences Inc. Warrant signed on 3438 Breath actuated inhaler Parkway Suite 300, Waston, Rec: 2613/4 dt Wef: 28/04/2005 Vide PT 3438 Att: SS & Co 02/11/2006 Florida 33326, USA 26/04/2006

Substituted Amide One Amgen Centre Drive, Filing Date: 26/04/2006 Amgen Inc. Warrant signed on: 3439 Derivatives and Methods Thousand Oaks, California Rec: 2696/2697 dt Wef: 27/04/2005 Vide PT 3439 Att: CCA Interserv Ltd. 02/11/2006 of Use 91320 - 1799, USA 27/04/2006

200 Great Valley Parkway, Mailcode RA -1-5, Malvern, Anti - il- 6 Antibodies, Centocor Inc. & Applied Filing Date: 27/04/2006 PA 19355, Pensylvania, USA Wef: 29/04/2005 Warrant signed on: 3440 Compositions, Methods Molecular Evolution Inc. Rec: 2675/2676 dt Vide PT 3440 & 3520 Dunhill Street, San Wef: 03/05/2005 02/11/2006 and Uses Att: EMD Advocates 27/04/2006 Diego , CA 92121 California, USA

C 5 Substituted P.O. Box 4000, Route 206 Filing Date: 27/04/2006 Quinazoline Derivatives Bristol - Myers Squibb and Province Line Road, Rec: 2712/2713 dt Warrant signed on: 3441 as Selective Estrogen Company Princeton, New Jersey Wef: 28/04/2005 Vide PT 3441 27/04/2006 02/11/2006 Receptor Beta Att: MAMO TCV Advocates 08543-4000, United States Modulators. of America

6-10 Koishikawa, 4-chome, Filing Date: 28/04/2006 Mono - Lysine Salts of Eisai Co. Ltd. Warrant signed on: 3442 Bunkyo-ku, Tokyo 112-8088, Rec: 2837/2838 dt Wef: 03/05/2005 Vide PT 3442 Azole Compounds Att: GS Services Ltd. 21/11/2006 Japan 03/05/2006

Anti-Interferon Gama Filing Date: 28/04/2006 Nov. Immune S.A. 64 Av. De la Roseraie, CH- Warrant signed on 3443 Antibodies and Methods Rec: 2988/9 dt Wef: N/A Vide PT 3443 Attn: S S & Co. 1211, Geneva, Switzerland 17/12/2007 of Use Thereof 08/05/2006 Antibodies Directed 230 E. Grande Avenue, Filing Date: 28/04/2006 Against Amyloid - Beta Rinat Neuroscience Corp. Wef: 29/04/2005 Warrant signed on: 3444 South San Francisco, Rec: 2995/2996 dt Vide PT 3444 Peptide and Methods Att: SS & Co. Wef: 01/08/2005 02/11/2006 California 94080, USA 08/05/2006 using same

One Angen Centre Drive, Filing Date: 28/04/2006 Methods of Inhibiting a Amgen Inc. Warrant signed on: 3445 Thousand Oaks, California Rec: 2840/2841 dt Wef: 28/04/2005 Vide PT 3445 GPCR Att: Dr. M. Chetcuti Cauchi 02/11/2006 91320 - 1799, USA 03/05/2006

Warner -Lambert 201 Tabor Road, Morris Filing Date: 02/05/2006 Wef: 05/05/2005 Warrant signed on: 3446 Androgen Modulators Company LLC Plains, New Jersey 07950, Rec: 2979/2980 dt Vide PT 3446 Wef: 18/05/2005 21/11/2006 Att: SS & Co. USA 08/05/2006

Filing Date: 02/05/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on: 3447 New Compounds Rec: 2982/2983 dt Wef: 09/05/2005 Vide PT 3447 Att: SS & Co. Sweden 21/11/2006 08/05/2006

Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 02/05/2006 Novel Chemical Warrant signed on: 3448 Corporation Box 7929 Philadelphia, PA Rec: 2985/2986 dt Wef: 03/05/2005 Vide PT 3448 Compounds 21/11/2006 Att: SS & Co. 19101, USA 08/05/2006

Filing Date: 02/05/2006 Pfizer Limited Ramsgate Road, Sandwich , Warrant signed on: 3449 Purine Derivatives Rec: 2935/2936 dt Wef: 04/05/2005 Vide PT 3449 Att: SS & Co. Kent CT 13 9NJ, England 21/11/2006 04/05/2006

208 Bath Road Slough, Wef: 03/05/2005 Berkshire SL1 3WE, United Filing Date: 02/05/2006 Wef: 24/02/2006 UCB S.A & Amgen Inc. Kingdom & One Amgen Warrant signed on: 3450 Binding Agents Rec: 2849/2850 dt Wef: 13/03/2006 Vide PT 3450 Att: MAMO TCV Advocates Centre Drive Thousand 21/11/2006 03/05/2006 Wef: 17/04/2006 Oaks, California 91320 - Wef: 25/04/2006 1799, USA

Solid Transdermal Filing Date: 02/05/2006 Schering AG Muillerstrasse 178, Berlin Warrant signed on: 3451 Therapeutic System with Rec: 2846/2847 dt Wef: 02/05/2005 Vide PT 3451 Att: MAMO TCV Advocates 13353, Germany 21/11/2006 U.V Absorber 03/05/2006

P.O. Box 4000, Route 206 Filing Date: 02/05/2006 Bristol-Myers Squibb and Province Line Road, Formulations of a Rec: 2844/2845 dt Warrant signed on: 3452 Company Princeton, New Jersey Wef: 05/05/2005 Vide PT 3452 SRC/ABL Inhibitor 03/05/2006 21/11/2006 Att: MAMO TCV Advocates 08543-4000, United States of America Filing Date: 02/05/2006 Warrant signed on: Method of Peptide Lonza AG Muenchensteinerstrasse 38, Rec: 2836/43 dt Wef: 04/05/2005 3453 21/11/2006 Vide PT 3453 Synthesis Att: Dr.M. Chetcuti-Cauchi 4002 Basel, Switzerland 03/05/2006 Wef: 18/07/2005

Synthesis and Preparations of Fructuos Gelabert, 6-8, Filing Date: 03/05/2006 Medichem SA Wef: 03/05/2005 Warrant signed on: 3454 Narwedine, 08970 Sant Joan Despi, Rec: 2868/2869 dt Vide PT 3454 Att: SS & Co. Wef: 30/09/2005 21/11/2006 Galanthamine and Barcelona, Spain 04/05/2006 related novel compounds

Process for the Fructuos Gelabert, 6-8, Filing date: 04/05/2006 Medichem SA Warrant signed on: 3455 Preparation of 08970 Sant Joan Despi, Rec: 2998/9 dt Wef: 04/05/2005 Vide PT 3455 Att: SS & Co. 21/11/2006 Tamsulosin Barcelona, Spain 08/05/2006

Process for the Fructuos Gelabert, 6-8, Filing Date: 05/05/2006 Medichem SA Warrant signed on: 3456 Preparation of Losartan 08970 Sant Joan Despi, Rec: 2969/70 dt Wef: 05/05/2005 Vide PT 3456 Att: SS & Co. 21/11/2006 and Its Salts Barcelona, Spain 08/05/2006

New Solid Crystalline form of Pantoprazole Fructuos Gelabert, 6-8, Filing Date: 05/05/2006 Medichem SA Warrant signed on: 3457 Free Acid Salts Derived 08970 Sant Joan Despi, Rec: 2972/2973 dt Wef: 06/05/2005 Vide PT 3457 Att: SS & Co. 21/11/2006 Therefrom and process Barcelona, Spain 08/05/2006 for their Preparation

Process of making Geminal Biphosphonic Medichem SA Filing Date: 05/05/2006 Acids and Pol. Ind. Celra, 17460 Celra, Warrant signed on: 3458 Att: Chetcuti Cauchi Rec: 2975/2976 dt Wef: 06/05/2005 Vide PT 3458 Pharmaceutically Girona, Spain 21/11/2006 Advocates 08/05/2006 Acceptable Salts and/or Hydrates thereof

Filing Date: 09/05/2006 AstraZeneca AB SE 15185 Sodertalje, Wef: 16/05/2005 Warrant signed on: 3459 Chemical Compounds Rec: 3096/3097 dt Vide PT 3459 Att: SS & Co. Sweden Wef: 30/09/2005 12/12/2006 10/05/2006

Pharmaceutical Filing Date: 09/05/2006 Compositions Novartis AG Lichtstrasse 35, 4056 Basel, Warrant signed on: 3460 Rec: 3099/3100 dt Wef: 10/05/2005 Vide PT 3460 Comprising Imatinib and Att: SS & Co. Switzerland 21/11/2006 10/05/2006 a Release Retardant 1,6-Dihydro-1,3,5,6- tetraaza-as-uidacine P.O. Box 4000, Route 206 based tricyclic Bristol-Myers Squibb and Province Line Road, Filing Date: 09/05/2006 Wef: 10/05/2005 Warrant signed on: 3462 compounds and Company Princeton, New Jersey Rec: 3090/3091 dt Vide PT 3462 Wef: 08/05/2006 21/11/2006 pharmaceutical Att: MAMO TCV Advocates 08543-4000, United States 10/05/2006 compositions of America comprising same

P.O. Box 4000, Route 206 Bristol-Myers Squibb and Province Line Road, Filing Date: 09/05/2006 Warrant signed on: 3463 Dosing Regimen Company Princeton, New Jersey Rec: 3057/3058 dt Wef: 13/05/2005 Vide PT 3463 21/11/2006 Att: MAMO TCV Advocates 08543-4000, United States 10/05/2006 of America

Glaxo Wellcome House, Filing Date: 11/05/2006 Glaxo Group Limited Berkeley Avenue, Greenford Warrant signed on: 3464 Vaccine Composition Rec: 3348/3349 dt Wef: 12/05/2005 Vide PT 3464 SS & Co. , Middlesex UB6 0NN, Great 21/11/2006 17/05/2006 Britain

New Phenylpyridylpiperazine Compounds, A Process 12, Place De La Defense, Filing Date: 11/05/2006 Les Laboratoires Servier Warrant signed on: 3465 for their Preparation and 92415 Courbevoie Cedex, Rec: 3351/3352 dt Wef: 12/05/2005 Vide PT 3465 Att: SS & Co 21/11/2006 Pharmaceutical France 17/05/2006 Compositions Containing them

New Phenylpyridylpiperazine Compounds, A Process 12, Place De La Defense, Filing Date: 11/05/2006 Les Laboratoires Servier Warrant signed on: 3466 for their Preparation and 92415 Courbevoie Cedex, Rec: 3354/3355 dt Wef: 12/05/2005 Vide PT 3466 Att: SS & Co. 21/11/2006 Pharmaceutical France 17/05/2006 Compositions Containing them

Filing Date: 11/05/2006 Compounds And IRM LLC Hurst Holme, 12 Trott Road, Rec: 3357/3358 dt Warrant signed on: 3467 Compositions Protein Wef: 13/05/2005 Vide PT 3467 Att: SS & Co. Hamilton, Bermuda HM 11 17/05/2006 21/11/2006 Kinase Inhibitors

Formulations Containing Fructuos Gelabert, 6-8, Filing Date: 12/05/2006 Combino Pharm SL Warrant signed on: 3468 Pantoprazole Free Acid 08970 Sant Joan Despi, Rec: 3543/3544 dt Wef: 13/05/2005 Vide PT 3468 Att: SS & Co. 12/12/2006 and Its Salts Barcelona, Spain 19/05/2006 Pharmaceutical Schering Mullerstrasse 178, Berlin Wef: 13/05/2005 composition comprising Filing Date: 15/05/2006 Aktiengesellschaft & 13353, Germany & An Wef: 03/04/2006 Warrant signed on 3469 progestogens srd/ch Rec: 3441/2 dt Vide PT 3469 Merck Eprova AG Laternenacker 5, Wef: 25/05/2006 10/10/2007 estogens A - 5 - methyl - 17/05/2006 Att: MAMO TCV Advocates Schaffhousen 5, Switzerland Wef: 03/04/2006 (65)- tetrahydrofolate

Filing Date: 16/05/2006 Imidazoquinolines as Novartis A.G Lichtstrasse 35, 4056 Basel, Warrant signed on: 3470 Rec: 3359/3360 dt Wef: 20/05/2005 Vide PT 3470 Lipid Kinase Inhibitors Att: SS & Co. Switzerland 12/12/2006 17/05/2006

GlaxoSmithKline Filing Date: 16/05/2006 Rue de L' institut 89, B-1330 Wef: 17/05/2005 Warrant signed on: 3471 Novel Device Biologicals S.A Rec: 3361/3362 dt Vide PT 3471 Rixensart, Belgium 12/12/2006 Att: SS & Co. 17/05/2006

Filing date: 16/05/2006 Rec. 3364+3365 of AstraZeneca AB SE. 15185 wef: 23/05/2005 Warrant signed on: 3472 New Compounds II 17/05/2006 Vide PT 3472 Att: SS & Co. Sodertalje, Sweden wef: 23/05/2005 12/12/2006 Claims Fee Lm70 Rec. 3366 of 17/05/2006

Filing Date: 16/05/2006 AstraZeneca AB SE 15185 Sodertalje, Wef: 23/05/2005 Warrant signed on: 3473 New Compounds I Rec: 3367/3368 dt Vide PT 3473 Att: SS & Co. Sweden Wef: 23/05/2005 12/12/2006 17/05/2006

Human Monoclonal Antibodies that Bind to Filing Date: 16/05/2006 very Late Antigen-1 for Amgen Fremont Inc. 6701 Kaiser Drive, Fremont, Warrant signed on: 3474 Rec: 3370/3371 dt Wef: 16/05/2005 Vide PT 3474 the Treatment of Att: SS & Co. California 94555, USA 12/12/2006 17/05/2006 Inflammation and Other Disorders

Heterocyclic Inhibitors of Array Biopharma Inc. & 3200 Walnut Street, Boulder, Filing Date: 17/05/2006 Warrant signed on: 3475 MEK and Methods of use Astrazeneca AB Colorado 80301, USA & SE Rec: 3341/3342 dt Wef: 18/05/2005 Vide PT 3475 12/12/2006 Thereof Att: 15185 Sodertalje, Sweden 17/05/2006

Janssen Pharmaceutica Filing Date: 18/05/2006 Process for Preparation Turnhoutseweg 30, B-2340 Warrant signed 3477 N.V Rec: P585582 dt Wef: N/A Vide PT 3477 of Sulfamide Derivatives Beerse, Belgium 12/12/2006 Att: EMD Advocates 18/05/2006 200, Great Valley Parkway, Anti - MCP -1 Antibodies, Filing Date: 18/05/2006 Centocor Inc. Mailcode RA -1 - 5, Malvern, Warrant signed on: 3478 Compositions, Methods Rec: P585582 dt Wef: N/A Vide PT 3478 Att: EMD Advocates PA 19355, Pensylvania 11/11/2007 and uses 18/05/2006 USA

Janssen Pharmaceutica Filing Date: 18/05/2006 Pediatric Formulation of Turnhoutseweg 30, B-2340 Warrant signed on: 3479 N.V Rec: P585582 dt Wef: N/A Vide PT 3479 Topiramate Beerse, Belgium 12/12/2006 Att: EMD Advocates 18/05/2006

Selected Tetracyclic Janssen Pharmaceutica Tetra Hydrofuran Turnhoutseweg 30, B-2340 Filing Date: 18/05/2006 Warrant signed on: 3480 N.V Wef: N/A Vide PT 3480 Derivatives Containing Beerse, Belgium P585582 of 18/05/2006 12/12/2006 Att: EMD Advocates Cyclic Amine Side chain

Interferon - Beta gene Filing Date: 18/05/2006 therapy using in Shering AG Warrant signed on: 3481 Berlin 13342, Germany Rec: 3474/5 dt Wef: 19/05/2005 Vide PT 3481 improved, regulated Att: MAMO TCV Advocates 12/12/2006 18/05/2006 expression system

P.O. Box 4000, Route 206 Pyrrolopyridine Based Bristol - Myers Squibb and Province Line Road, Filing Date: 18/05/2006 Inhibitors of Dipeptidyl Wef: 20/05/2005 Warrant signed on: 3482 Company Princeton, New Jersey Rec: 3471/3472 dt Vide PT 3482 Peptidase IV and Wef: 09/05/2006 12/12/2006 Att: MAMO TCV Advocates 08543-4000, United States 18/05/2006 Methods of America

Treatment of Disease Filing Date: 18/05/2006 Using an Improved Shering AG Warrant signed on: 3483 Berlin 13342, Germany Rec: 3468/3469 dt Wef: 19/05/2005 Vide PT 3483 Related Expression Att: MAMO TCV Advocates 12/12/2006 18/05/2006 System

Fructuos Gelabert, 6-8, Filing Date: 18/05/2006 Formulations Containing Combino Pharm SL Warrant signed on: 3484 08970 Sant Joan Despi, Rec: 3479/3481 dt Wef: 18/05/2005 Vide PT 3484 Losartan and/or its Salts Att: SS & Co. 12/12/2006 Barcelona, Spain 18/05/2006

Compositions and One Amgen Centre Drive, Filing Date: 18/05/2006 Methods for Increasing Amgen Inc. Warrant signed on: 3485 Thousand Oaks, California Rec: 3534/3535 dt Wef: 19/05/2005 Vide PT 3485 the Stability of Att: CCA Interserv Ltd. 12/12/2006 91320 - 1799, USA 19/05/2006 Antibodies

Formulations of 126 East Lincoln Avenue, Wef: 20/05/2005 Suberoylanilide Merck & Co. Inc. & Aton Rahway, NJ 07065, USA & Filing Date: 18/05/2006 Wef: 23/06/2005 Warrant signed on: 3486 Hydroxamic Acid and Pharma Inc. 33 Avenue Louis Pastour, Rec: 3540/3541 dt Vide PT 3486 Wef: 16/05/2006 12/12/2006 Methods for Producing Att: CCA Interserv Ltd. Boston, MA 02115, USA 19/05/2006 Wef: 16/05/2006 Same Compounds, Pharmaceutical One Amgen Centre Drive, Filing Date: 18/05/2006 Compositions and Amgen Inc. Warrant signed on: 3487 Thousand Oaks, California Rec: 3537+3538 dt Wef: 20/05/2005 Vide PT 3487 Methods for their Use in Att: CCA Interserv Ltd. 12/12/2006 91320 - 1799, USA 19/05/2006 Treating Metabolic Disorders

Lichtstrasse 35, 4056 Basel, Novartis AG & Vizuron Filing Date: 19/05/2006 N-Formyl Hydroxylamine Switzerland & 455 South Warrant signed on: 3488 Pharmaceuticals Inc. Rec: 3593/3594 dt Wef: 23/05/2005 Vide PT 3488 Compounds Gulph Road, King of Prussia, 12/12/2006 Att: SS & Co. 19/05/2006 PA 191406

Filing Date: 19/05/2006 Combination Therapy for Eastern Point Road Pfizer Products Inc. Rec: 3596/3597 dt Wef: 27/05/2005 Warrant signed on: 3489 Treating Obesity or Groton, Connecticut 06340 Vide PT 3489 Att: SS & Co. 19/05/2006 Wef: 07/07/2005 12/12/2006 Maintaining Weight Loss USA

Filing Date: 19/05/2006 AstraZeneca AB SE 15185 Sodertalje, Wef: 28/05/2005 Warrant signed on: 3490 Chemical Compounds Rec: 3598/3599 dt Vide PT 3490 Att: SS & Co. Sweden Wef:14/01/2006 12/12/2006 19/05/2006

Derivatives of 4-(2-Amino- Filing Date: 19/05/2006 1-Hydroxyethyl) Phenol Almirall Prodesfarma SA Ronda del General Mitre Warrant signed on: 3491 Rec: 3601/2 dt Wef: 20/05/2005 Vide PT 3491 as Agonists of the B2 Att: SS & Co. 151, 08022 Barcelona, Spain 12/12/2006 19/05/2006 Adrenergic Receptor

Pyrazole Compounds 2-1 Toranomon 2- Chome, Filing Date: 19/05/2006 and Antidiabetics Japan Tobacco Inc. Warrant signed on: 3492 Minato-ku, Tokyo 105-8422, Rec: 3590/3591 dt Wef: 20/12/2005 Vide PT 3492 Comprising the Pyrazole Att: SS & Co. 12/12/2006 Japan 19/05/2006 Compounds

Wef: 27/05/2005 Filing Date: 23/05/2006 AstraZeneca AB SE. 15185 Sodertalje, Wef: 09/07/2005 Warrant signed on: 3496 Chemical Compounds Rec: 3700/3701 dt Vide PT 3496 Att: SS & Co. Sweden Wef: 09/08/2005 12/12/2006 23/05/2006 Wef:24/01/2005

Benzimidazole 901 Gateway Boulevard, Filing Date: 23/05/2006 Wef: 25/05/2005 Carboxamide Theravance Inc. Warrant signed on: 3497 South San Francisco, CA Rec: 3697/3698 dt Wef: 25/05/2005 Vide PT 3497 Compounds as 5-HT4 Att: SS & Co. 12/12/2006 94080, USA 23/05/2006 Wef: 08/12/2005 Receptor Agonists Smithkline Beecham One Franklin Plaza, P.O. Filing Date: 23/05/2006 Novel Chemical Warrant signed on: 3498 Corporation Box 7929, Philadelphia, PA Rec: 3694/3695 dt Wef: 23/05/2005 Vide PT 3498 Compounds 12/12/2006 Att: SS & Co. 19101, USA 23/05/2006 MT PT Patent Title Applicant Name Applicant Address MT Application Date Priority Date Status Abstract No Filing Date: 23/05/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3499 Chemical Compounds Rec: 3691/3692 dt Wef: 27/05/2005 Vide PT 3499 Att: SS & Co. Sweden 12/12/2006 23/05/2006

Wef: 23/05/2005 Wef: 11/07/2005 Wef: 26/07/2005 Wef: 07/11/2005 Wef: 21/11/2005 Wef: 10/12/2005 Wef: 05/07/2005 Processes for preparing Teva Pharmaceutical 5. Basel Street , P.O. Box Filing Date: 23/05/2006 Wef: 06/07/2005 Warrant signed on 3500 Cinacalcet Hydrochloride Industries Ltd. 3190 , Petah Tiqva 49131, Rec: 3747/3748 dt Vide PT 3500 Wef: 20/07/2005 12/12/2006 Crystal Form 1 Att. CCA Interserv Ltd. Israel 25/05/2006 Wef: 09/08/2005 Wef: 08/11/2005 Wef: 24/04/2006 Wef: 24/10/2005 Wef: 31/10/2005 Wef: 02/11/2005 Wef: 01/12/2005

Filing Date: 23/05/2006 Laboratories Serono SA Centre Industriewl, 1267 Wef: 24/05/2005 Warrant signed on 3502 Spiro derivatives Rec: 3742/3743 dt Vide PT 3502 Att. CCA Interserv Ltd. Coinsins, Vaud, Switzerland Wef: 08/06/2005 28/09/2007 25/05/02006

6-10, Koishikawa, 4-chome, Filing Date: 24/05/2006 Eisa Co. Ltd. Warrant signed on 3503 Hydantoin compounds Bunkyo-ku, Tokyo Rec: P585590 dt Wef: 27/05/2005 Vide PT 3503 Att: EMD Advocates 11/01/2007 112-8088, Japan 24/05/2006

Process for Preparing (Alpha S, Beta R)-6- Bromo Alpha-[2- Janssen Pharmaceutica Filing Date: 24/05/2006 Turnhoutseweg 30, B-2340 Warrant signed on 3504 (dimethylamino)ethyl]-2- N.V. Rec: P585590 dt Wef: 25/05/2005 Vide PT 3504 Beerse, Belgium 12/12/2006 methoxy-alpha-1- Att: EMD Advocates 24/05/2006 naphthalenyl-beta-phenyl- 3-quinolineethanol

One Amgen Center Drive, Filing Date: 24/05/2006 Humanized anti-ahyloid Amgen Inc. Warrant signed on 3505 Thousand Oaks, California Rec: 3520/3521 dt Wef: N/A Vide PT 3505 antibody Att: J. Mifsud 17/12/2007 91320-1799, USA 26/05/2006

Biomarin Pharmaceutical Filing Date: 24/05/2006 105, Digital Drive, Novato, Warrant signed on 3506 Stable tablet formulation Inc. Rec: 3817/3818 dt Wef: N/A Vide PT 3506 California 94949, USA 17/12/2007 Att: J. Mifsud 26/05/2006 New process for the synthesis and new crystalline form of 12. Place De La Defense, F- Filing Date: 25/05/2006 Les Laboratoires Servier Warrant signed on 3507 agomelatine and 92415 Courbevoie Cedex, Rec: 3826/3827 dt Wef: N/A Vide PT 3507 Att: SS & Co. 17/12/2007 pharmaceutical France 26/05/2006 compositions containing it

Novel Substituted Tetracyclic Tetrahydrofuran, Janssen Pharmaceutica Filing Date: 25/05/2006 Turnhoutseweg 30, B-2340 Warrant signed on 3508 Pyrrolidine and N.V. Rec: P585592 dt Wef: 26/05/2005 Vide PT 3508 Beerse, Belgium 12/12/2006 Tetrahydrothiophene Att: EMD Advocates 25/05/2006 Derivatives and their use as medicament

P.O. Box 4000, Route 206 Withdrawn wef\: Bristol - Myers Squibb Filing Date: 26/05/2006 and Province Line Road, 3509 25/07/2006 Company Rec: 3814/3815 dt Wef: 26/05/2005 WITHDRAWN Vide PT 3509 Princeton, New Jersey Rec. 5378 of 28/07/2006 Att: MAMO TCV Andvocates 26/05/2006 08543-4000, USA

P.O. Box 4000, Route 206 N- Terminally Modified Bristol - Myers Squibb Filing Date:26/05/2006 and Province Line Road, Warrant signed on 3510 GLP-1 Receptor Company Rec: 3811/3812 dt Wef: 26/05/2005 Vide PT 3510 Princeton, New Jersey 12/12/2006 Modulators Att: MAMO TCV Andvocates 26/05/2006 08543-4000, USA

Filing Date: 26/05/2006 Process for Preparing 3,3-Medichem S.A. Pol. Ind. Celra, 17460 Celra, Warrant signed on 3512 Rec:. 3867/8 dt Wef: N/A Vide PT 3512 Diarylpropylamines Att: CC Advocates Girona, Spain 12/12/2006 29/05/2006

6701 Kaiser Drive, Fremont, Amgen Fremont Inc.& Filing Date: 30/05/2006 Antibodies Directed to California 94555, USA & SE- Warrant signed on 3513 Astrazeneca AB Rec: 3907/3908 dt Wef: 02/06/2005 Vide PT 3513 CD20 and uses thereof 15185 11/01/2007 Att: SS & Co. 31/05/2006 Sodertalje, Sweden

New Derivatives of Pyrrolytriazine together Filing Date: 30/05/2006 with methods for ISDIN. S.A Ar. Diagonal 520, 08006 Warrant signed on 3514 Rec: 3910/3911 dt Wef: 03/05/2005 Vide PT 3514 obtaining them and their Att: MAMO TCV Advocates Barcelona, Spain 11/01/2007 31/05/2006 use as protecting agents against UV Radiation

Formulations Containing Fructuos Gelabert, 6-8 , Filing Date: 02/06/2006 Combino Pharm, S.L. Warrant signed on 3515 Glimepiride and/or its 08970 Sant Joan Despi, Rec: 4004 /4005 dt Wef: 10/06/2005 Vide PT 3515 Att: SS & Co. 11/01/2007 Salts Barcelona, Spain 05/06/2006

Process for the Fructuos Gelabert, 6-8 , Medichem S.A. Filing Date: 02/06/2006 Wef: 06/06/2005 Warrant signed on 3516 Preparation of Tetrazolyl 08970 Sant Joan Despi, Vide PT 3516 Att: SS & Co. Rec: 4007/8 dt 05/06/2006 Wef: 09/02/2006 11/01/2007 Compounds Barcelona, Spain Cyclohexanesulfonyl Merck Sharp & Dohme Hertford Road, Hoddesdon, Filing Date: 02/06/2006 Wef: 06/06/2005 Derivatives as Glyt 1 Warrant signed on 3517 Limited Hertfordshire, EN11 9BU, Rec: 4001/4002 dt Wef: 17/08/2005 Vide PT 3517 Inhibitors to Treat 11/01/2007 Att: Dr.M. Chetcuti Cauchi United Kingdom 05/06/2006 Wef: 08/12/2005 Schizophrenia

Filing Date: 06/06/2006 Novartis AG. Lichtstrasse 35, 4056 Basel, Warrant signed on 3518 Organic Compounds Rec: 4086/4087 dt Wef: 08/06/2005 Vide PT 3518 Att: SS & Co. Switzerland 11/01/2007 08/06/2006

2-1, Toranomon 2-Chome, Filing Date: 06/06/2006 Japan Tobacco Inc. Wef: 08/06/2005 Warrant signed on 3519 Heterocyclic Compounds Minato - Ku, Tokyo 105- Rec: 4089/4090 dt Vide PT 3519 Att: SS & Co. Wef: 03/02/2005 11/01/2007 8422, Japan 08/06/2006

Immediate Release and High-Drug-Load Pharmaceutical Formulations of Filing Date: 06/06/2006 Schering AG Warrant signed on 3520 Micronised (4- Berlin 13342, Germany Rec: 4076/4077 dt Wef: 07/06/2005 Vide PT 3520 Att: MAMO TCV Advocates 27/01/2007 Chlorophenyl) [4- 08/06/2006 Pyridylmethyl) Phthalazine-1-YL] and Salts thereof

Immediate Release and High-Drug-Load Filing date: 06/06/2006 Pharmaceutical Rec. 4079+4080 of Formulations of Non- Schering AG Warrant signed on 3521 Berlin 13342, Germany 08/06/2006 wef: 07/06/2005 Vide PT 3521 Micronised (4-Chloro- Att: MAMO TCV Advocates 11/01/2007 Claims Fee Lm530 phenylyl) [4-(4-Pyridyl- Rec. 4081 of 08/06/2006 methyl) Phthalazine-1- YL] and Salts thereof

Filing Date: 06/06/2006 Inhibitors of Soluble Schering AG Warrant signed on 3522 Berlin 13342, Germany Rec: 4082/4083 dt Wef: 08/06/2005 Vide PT 3522 Adenylate Cyclase Att: MAMO TCV Advocates 11/01/2007 08/06/2006

Deutschland', Triq Mater Filing Date: 06/06/2006 Apparatus for conversion Joe Spiteri Sargent Attn: Warrant signed on 3523 Boni Consilli, Fgura PLA 20, Rec: P585603 dt Wef: N/A Vide PT 3523 of energy N/A 17/12/2007 Malta 06/06/2006

Process for the Filing Date: 08/06/2006 Novartis AG Lichtstrasse 35, 4056 Basel, Warrant signed on 3524 Synthesis of Organic Rec: 4069/70 dt Wef: 09/06/2005 Vide PT 3524 Att: SS & Co. Switzerland 11/01/2007 Compounds 08/06/2006

Filing Date: 08/06/2006 Process fo the synthesis Novartis AG Lichtstrasse 35, 4056 Basel, Warrant signed on 3525 Rec: 4071/4072 dt Wef: 09/06/2005 Vide PT 3525 of organic compounds Att: SS & Co. Switzerland 11/01/2007 08/06/2006

Process fo the synthesis Novartis AG Lichtstrasse 35, 4056 Basel, Filing date: 08/06/2006 Wef: 09/06/2005 Warrant signed on 3526 Vide PT 3526 of organic compounds Att: SS & Co. Switzerland Rec. 4074/5 dt 08/06/2006 Wef: 04/08/2005 11/01/2007 (521-5-(6-Quinoxaline- One Franklin Plaza, PO Filing Date: 08/06/2006 y(Methylidene)-2-[2,6- Smith Kline Beacham BOX 7929, Philadelphia, PA Warrant signed on 3527 Rec: 4066/4067 dt Wef: 08/06/2005 Vide PT 3527 Dichlorophenyl)amino]- Att: SS & Co. 19101, United States of 11/01/2007 08/06/2006 1,3-Thiazol-4(5H)-One America

P.O. Box 4000, Route 206 Triazolopyridinhe 11- Bristol - Myers Squibb and Province Line Road, Filing Date: 08/06/2006 Beta Hydroxysteroid Wef: 09/06/2005 Warrant signed on 3528 Company Princeton, New Jersey Rec: 4063/4064 dt Vide PT 3528 Dehydrogenase Type 1 Wef: 07/04/2005 29/01/2007 Att: MAMO TCV Advocates 08543-4000, United States 08/06/2006 Inhibitors of America

P.O. Box 4000, Route 206 Heteroaryl 11-Beta Bristol - Myers Squibb and Province Line Road, Filing Date: 08/06/2006 Hydroxysteroid Wef: 09/06/2005 Warrant signed on 3529 Company Princeton, New Jersey Rec: 4060/4061 dt Vide PT 3529 Dehydrogenase Type 1 Wef: 07/06/2005 29/01/2007 Att: MAMO TCV Advocates 08543-4000, United States 08/06/2006 Inhibitors of America

Filing Date: 08/06/2006 Thienopyrimidine and Janssen Pharmaceutica Turnhoutseweg 30, B-2340 Rec: P585604 dt Wef: 10/06/2005 Warrant signed on 3530 Thienopyridine Kinase N.V Vide PT 3530 Beerse, Belgium 08/06/2006 Wef: 10/05/2006 11/01/2007 Modulators Att: EMD Advocates

Janssen Pharmaceutica Filing Date: 08/06/2006 Quinoline Derivatives as Turnhoutseweg 30, B-2340 Wef: 08/06/2005 Warrant signed on 3531 N.V Rec: P585604 dt Vide PT 3531 Antibacterial Agents Beerse, Belgium Wef: 08/12/2006 11/01/2007 Att: EMD Advocates 08/06/2006

Intermediates Useful in the Synthesis of Wef: 10/06/2005 Janssen Pharmaceutica Filing Date: 08/06/2006 Alkylquinidine and Turnhoutseweg 30, B-2340 Wef: 27/10/2005 Warrant signed on 3532 N.V Rec: P585604 dt Vide PT 3532 Alkylquinazoline Kinase Beerse, Belgium Wef: 05/04/2006 11/01/2007 Att: EMD Advocates 08/06/2006 Modulators, and Related Methods of Synthesis

Aminoquinoline and Janssen Pharmaceutica Filing Date: 08/06/2006 Turnhoutseweg 30, B-2340 Wef: 10/06/2005 Warrant signed on 3533 Aminoquinazoline Kinase N.V Rec: P585604 dt Vide PT 3533 Beerse, Belgium Wef: 16/05/2006 11/01/2007 Modulators Att: EMD Advocates 08/06/2006

Alkylquinoline and Janssen Pharmaceutica Filing Date: 08/06/2006 Turnhoutseweg 30, B-2340 Wef: 10/06/2005 Warrant signed on 3534 Alkylquinazoline Kinase N.V Rec: P585604 dt Vide PT 3534 Beerse, Belgium Wef: 27/10/2005 11/01/2007 Modulators Att: EMD Advocates 08/06/2006

Janssen Pharmaceutica Filing Date: 08/06/2006 Aminopyrimidines as Turnhoutseweg 30, B-2340 Wef: 10/06/2005 Warrant signed on 3535 N.V Rec: P585604 dt Vide PT 3535 Kinase Modulators Beerse, Belgium Wef: 16/12/2005 11/01/2007 Att: EMD Advocates 08/06/2006

Janssen Pharmaceutica Filing Date: 08/06/2006 Aminopyrimidines as Turnhoutseweg 30, B-2340 Wef: 10/06/2005 Warrant signed on 3536 N.V Rec: P585604 dt Vide PT 3536 Kinase Modulators Beerse, Belgium Wef: 16/12/2005 11/01/2007 Att: EMD Advocates 08/06/2006 Filing Date: 09/06/2006 Wef: 10/06/2005 Direct Compression Novartis AG. Lichtstrasse 35, 4056 Basel, Warrant signed on 3538 Rec: 4100/4101 dt Wef: 14/06/2005 Vide PT 3538 Formulation and Process Att: SS & Co. Switzerland 11/01/2007 09/06/2006 Wef: 15/06/2005

Modified Release 1-[3- Hydrody-Adamant-1- Filing Date: 09/06/2006 Novartis AG. Lichtstrasse 35, 4056 Basel, Wef: 10/06/2005 Warrant signed on 3539 Ylamino)-Acetyl]- Rec: 4103/4104 dt Vide PT 3539 Att: SS & Co. Switzerland Wef: 15/06/2006 11/01/2007 Pyrrolidine-2(S)- 09/06/2006 Carbonitrile Formulation

Process for Preparation Teva Pharmaceutical 5 Basel Street, P.O. Box Filing Date: 08/06/2006 Warrant signed on 3541 of Sertraline Industries Ltd. 3190, Petah Tiqva 49131, Wef: 09/06/2005 Vide PT 3541 Rec: 4173/4 dt 12/06/2006 11/01/2007 Hydrochloride Form I Att: CC Advocates Israel

Crystalline Forms of Tera Pharmaceutical 5 Basel Street, P.O. Box Filing Date: 09/06/2006 Warrant signed on 3542 Carvedilol and Processes Industries Ltd. 3190, Petah Tiqva 49131, Rec: 4171/4172 dt Wef: 09/06/2005 Vide PT 3542 11/01/2007 for their preparation Att. CCA Interserv Ltd. Israel 12/06/2006

New Physical form of N,N- Filing Date: 12/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3543 Disubstituted Rec: 4233/4234 dt Wef: 20/05/2005 Vide PT 3543 Att: SS & Co. Sweden 11/01/2007 Oxabispidines 13/06/2006

New Compounds for the Filing Date: 12/06/2006 AstraZeneca AB SE 15185 Sodertalje, Wef: 13/06/2005 Warrant signed on 3544 Treatment of Cardiac Rec: 4237/4238 dt Vide PT 3544 Att: SS & Co. Sweden Wef: 15/12/2005 11/01/2007 Arrythmias 13/06/2006

235 East 42nd Street, New Filing Date: 12/06/2006 N-(Pyridin-2-Yl)- Pfizer Inc. Wef: 16/06/2005 Warrant signed on 3545 York, New York - 10017, Rec: 4240/4241 dt Vide PT 3545 Sulfonamide Derivatives SS & Co. Wef: 09/12/2005 18/01/2007 USA 13/06/2006

Filing Date: 12/06/2006 AstraZeneca AB SE 15185 Sodertalje, Rec: 4243/4244 dt Warrant signed on 3546 Chemical Compounds Wef: 20/06/2005 Vide PT 3546 Att: SS & Co. Sweden 13/06/2006 11/01/2007

N-amide derivatives of 8- Ronda del General Mitre Filing Date: 13/06/2006 Almirall Prodesfarma S.A. 3547 azabicyclo[3.2.1]oct-3-yl 151, 08022 Barcelona, Rec: P585608 dt Wef: 14/06/2005 WITHDRAWN Vide PT 3547 Att: Ganado & Associates as CCR1 antagonists Spain 13/06/2006

Filing Date: 13/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3548 New Compounds II Rec: 4253/4254 dt Wef: 17/06/2005 Vide PT 3548 Att: SS & Co. Sweden 11/01/2007 13/06/2006

Glaxo Wellcome House, Filing Date: 13/06/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3549 Novel Pharmaceutical Rec: 4255/4256 dt Wef: 15/06/2005 Vide PT 3549 Att: SS & Co. Greenford, Middlesex UB 11/01/2007 13/06/2006 ONN, Great Britain Filing Date: 13/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3550 Chemical Compounds Rec: 4258/4259 dt Wef: 16/06/2005 Vide PT 3550 Att: SS & Co. Sweden 11/01/2007 13/06/2006

N-Amide Derivatives of 8- Ronda Del General Mitre Filing Date: 13/06/2006 Almirall Prodesfarma SA Warrant signed on 3551 Azabicyclo[3,2,1] oct 3- 151, 08022 Barcelona, Rec: 4261/4262 dt Wef: 14/06/2005 Vide PT 3551 Att: SS & Co. 11/01/2007 YL as CCR1 antagonists Spain 13/06/2006

One Amgen Centre Drive, Filing Date: 13/06/2006 Self buffering protein Amgen Inc. Warrant signed on 3553 Thousand Oaks, California Rec: 4319/4320 dt Wef: 14/06/2005 Vide PT 3553 formulations Att: CCA Interserv Ltd. 10/10/2007 91320 - 1799, USA 16/06/2006

P.O. Box 4000, Route 206 Modulators of the Bristol - Myers Squibb and Province Line Road, Filing Date: 14/06/2006 Glucocorticoid Receptor Wef: 14/06/2005 Warrant signed on 3554 Company Princeton, New Jersey Rec: 4316/4317 dt Vide PT 3554 AP-1 and /or NF-kB Wef: 15/03/2006 29/01/2007 Att: MAMO TCV Advocates 08543-4000, United States 16/06/2006 Activity and use thereof of America

Modified and Immediate Filing Date: 14/06/2006 Forest Laboratories Inc. 909 Third Avenue, New Warrant signed on 3555 Release Memantine Bead Rec: 4310/4311 dt Wef: 16/06/2005 Vide PT 3555 Att: Dr.M.Chetcuti-Cauchi York 10022, USA 29/01/2007 Formulation 16/06/2006

APR Applied Pharma Filing Date: 14/06/2006 Diclofenac Formulations Via Corti 5, Balerna 6828, Wef: 17/06/2005 Warrant signed on 3556 Research SA Rec: 4313/4314 dt Vide PT 3556 and Methods of Use Switzerland Wef: 17/06/2005 11/01/2007 Att: Dr.M.Chetcuti-Cauchi 16/06/2006

One Franklin Plaza, PO Smith Kline Beacham Filing Date: 16/06/2006 BOX 7929, Philadelphia, PA Warrant signed on 3557 Novel Compounds Corporation Rec: 4352/4353 dt Wef: 17/06/2005 Vide PT 3557 1910, United States of 11/01/2007 Att: SS & Co. 19/06/2006 America

Filing Date: 16/06/2006 Use of Sanglifehrin in Novartis AG. Lichtstrasse 35, 4056 Basel, Warrant signed on 3558 Rec: 4355/4356 dt Wef: 17/06/2005 Vide PT 3558 HCV Att: SS & Co. Switzerland 11/01/2007 19/06/2006

Filing Date: 16/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3559 Chemical Compounds II Rec: 4358/4359 dt Wef: 22/06/2005 Vide PT 3559 Att: SS & Co. Sweden 11/01/2007 19/06/2006

One Angen Centre Drive, Filing Date: 16/06/2006 Benzamide Derivatives Angen Inc. Warrant signed on 3560 Thousand Oaks, California Rec: 4361/4362/4363 dt Wef: 17/06/2005 Vide PT 3560 and Uses Related thereto Att: SS & Co 11/01/2007 91320 - 1799, USA 19/06/2006 436 Cambridge Science Park, Milton Road, Cambridge, CB4 OQA, UK Astex Therapeutics Ltd. & Aryl-Alkylamines and & SE 15185, Sodertalje, Astrazeneca AB & Cancer Filing Date: 16/06/2006 Wef: 21/06/2005 Heteroaryl Alkylamines Sweden & Sardinia House, Warrant signed on 3561 Research Technology Ltd. Rec: 4365/4366 dt Wef: 21/06/2005 Vide PT 3561 as Protein Kinase Sardinia Street, London WC 11/01/2007 & The Institute of Cancer 19/06/2006 Wef: 03/04/2006 Inhibitors 2A 3NL, UK & Royal Cancer Research Hospital, 123 Old Brompton Road, London SW7 3RP, UK

Novel Janssen Pharmaceutica Filing Date: 16/06/2006 Tetracyclichydrofuran Turnhoutseweg 30, B-2340 Warrant signed on 3562 N.V Rec: P585614 dt Wef: 17/06/2005 Vide PT 3562 Derivatives Containing a Beerse, Belgium 11/01/2007 Att: EMD Advocates 19/06/2006 Cyclic Amine Side Chain

P.O. Box 4000, Route 206 Bicyclic Heterocycles as Bristol - Myers Squibb and Province Line Road, Filing Date: 19/06/2006 Warrant signed on 3563 Cannabinoid-1 Receptor Company Princeton, New Jersey Rec: 4406/4407 dt Wef: 17/06/2005 Vide PT 3563 29/01/2007 Modulators Att: MAMO TCV Advocates 08543-4000, United States 20/06/2006 of America

P.O. Box 4000, Route 206 Bicyclic Heterocycles as Bristol - Myers Squibb and Province Line Road, Filing Date: 19/06/2006 Warrant signed on 3564 Cannabinoid-1 Receptor Company Princeton, New Jersey Rec: 4403/4404 dt Wef: 17/06/2005 Vide PT 3564 29/01/2007 Modulators Att: MAMO TCV Advocates 08543-4000, United States 20/06/2006 of America

P.O. Box 4000, Route 206 Azabicyclic Heterocycles Bristol - Myers Squibb and Province Line Road, Filing Date: 19/06/2006 Warrant signed on 3565 as Cannabinoid Receptor Company Princeton, New Jersey Rec: 4400/4401 dt Wef: 17/06/2005 Vide PT 3565 29/01/2007 Modulators Att: MAMO TCV Advocates 08543-4000, United States 20/06/2006 of America

P.O. Box 4000, Route 206 Triazolopyrimidine Bristol - Myers Squibb and Province Line Road, Filing Date: 19/06/2006 Wef: 17/06/2005 Warrant signed on 3566 Cannabinoid Receptor 1 Company Princeton, New Jersey Rec: 4397/4398 dt Vide PT 3566 Wef: 16/06/2006 11/01/2007 Antagonists Att: MAMO TCV Advocates 08543-4000, United States 20/06/2006 of America

P.O. Box 4000, Route 206 Triazolopyrimidine Bristol - Myers Squibb and Province Line Road, Filing Date: 19/06/2006 Wef: 17/06/2005 Warrant signed on 3567 Cannabinoid Receptor 1 Company Princeton, New Jersey Rec: 4395/4396 dt Vide PT 3567 11/01/2007 Antagonists Att: MAMO TCV Advocates 08543-4000, United States 20/06/2006 of America Process for the Fructuos Gelabert, 6-8, Filing Date: 19/06/2006 Medichem S.A. Warrant signed on 3568 Preparation of Adapalene 08970 Sant Joan Despi, Rec: 4391/4392/4393 dt Wef: 17/06/2005 Vide PT 3568 Att: SS & Co. 11/01/2007 and Related Compounds Barcelona, Spain 20/06/2006

Filing Date: 19/06/2006 126 East Lincoln Avenue, Wef: 23/06/2005 Tyrosine Kinase Merck & Co. Inc. Rec: 4441/4442 dt Warrant signed on 3569 Rahway, NJ 07065, USA Wef: 21/10/2005 Vide PT 3569 Inhibitors Att: CCA Interserv Ltd. 20/06/2006 11/01/2007 Wef: 05/04/2006

Filing Date: 20/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3570 Chemical Compounds VII Rec: 4444/4445 dt Wef: 22/06/2005 Vide PT 3570 Att: SS & Co. Sweden 11/01/2007 21/06/2006

Filing Date: 20/06/2006 Chemical Compounds AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3571 Rec: 4447/4448 dt Wef: 22/06/2005 Vide PT 3571 111 Att: SS & Co. Sweden 11/01/2007 21/06/2006

Filing Date: 20/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3572 Chemical Compounds VI Rec: 4450/4451 dt Wef: 22/06/2005 Vide PT 3572 Att: SS & Co. Sweden 11/01/2007 21/06/2006

Filing Date: 20/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3573 Chemical Compound IV Rec: 4454/4455 of Wef: 22/06/2005 Vide PT 3573 Att: SS & Co. Sweden 11/01/2007 21/06/2006

Filing Date: 20/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3574 Chemical Compounds Rec: 4457/4458 dt Wef: 22/06/2005 Vide PT 3574 Att: SS & Co. Sweden 11/01/2007 21/06/2006

Filing Date: 21/06/2006 Hydrocodone Normaco Inc. 1440 Olympic Drive, Athens, Warrant signed on 3575 Rec: 4469/4470 dt Wef: 23/06/2005 Vide PT 3575 Polymorphs Att: EMD Advocates Georgia 30601, USA 11/01/2007 21/06/2006

Filing Date: 22/06/2006 A Mask for Directing the Yamamoto Limited 136, St. Christopher Street, Rec: 4490/4491 dt 3576 Wef: N/A WITHDRAWN Vide PT 3576 Respiratory Flow Att: Carmel A Buttigieg Valletta VLT 05, Malta 22/06/2006

A Retractable and Filing Date: 22/06/2006 Flexible Urinal and Yamamoto Limited 136, St. Christopher Street, Rec: 4488/4489 dt 3577 Wef: N/A WITHDRAWN Vide PT 3577 Devices With It Att: Carmel A Buttigieg Valletta VLT 05, Malta 22/06/2006 Correlated

A Shoe Incorporating a Filing Date: 22/06/2006 Yamamoto Limited 136, St. Christopher Street, 3578 Fan for a Real Ventilation Rec: 4486/4487 dt Wef: N/A WITHDRAWN Vide PT 3578 Att: Carmel A Buttigieg Valletta VLT 05, Malta Inside It 22/06/2006 A Sole for shoes which Filing Date: 22/06/2006 Yamamoto Limited 136, St. Christopher Street, 3579 alternated the pressure Rec: 4484/4485 dt Wef: N/A WITHDRAWN Vide PT 3579 Att: Carmel A Buttigieg Valletta VLT 05, Malta on the plantar foot 22/06/2006

Genelabs Technologies 505 Penobscot Drive, Filing Date: 23/06/2006 Heteroaryl Derivatives Warrant signed on 3581 Inc. Redwood City, CA 94063, Rec: 4525/4526 dt Wef: 24/06/2005 Vide PT 3581 For Treating Viruses 11/01/2007 Att: SS & Co. USA 23/06/2006

Non-Steroidal Filing Date: 23/06/2006 Schering AG Warrant signed on 3582 Progesterone Receptor Berlin 13342, Germany Rec: 4533/4534 dt Wef: 24/06/2005 Vide PT 3582 Att: MAMO TCV Advocates 11/01/2007 Modulators 23/06/2006

Use of Non-Steroidal Filing Date: 23/06/2006 Schering AG Warrant signed on 3583 Progesterone Receptor Berlin 13342, Germany Rec: 4536/4537 dt Wef: 24/06/2005 Vide PT 3583 Att: MAMO TCV Advocates 11/01/2007 Modulators 23/06/2006 MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Non-steroidal Filing Date: 23/06/2006 Schering AG Warrant signed on 3584 progesterne receptor Berlin 13342, Germany Rec: 4539/4540 dt Wef: 24/06/2005 Vide PT 3584 Att: MAMO TCV Advocates 11/01/2007 modulators 23/06/2006

P.O. Box 4000, Route Phenylglycinamide and Bristol-Myers Squibb 206 and Province Line Filing Date: 23/06/2006 pyridylgyinamide Wef: 24/06/2005 Warrant signed on 3585 Company Road, Princeton, New Rec: 4543/4542 dt Vide PT 3585 derivaties useful as Wef: 24/06/2005 11/01/2007 Att: MAMO TCV Advocates Jersey 08543-4000, 23/06/2006 anticoagulants United States of America

N-linked heterocycle P.O. Box 4000, Route antagonists of P2Y, Bristol-Myers Squibb 206 and Province Line Filing Date: 26/06/2006 Wef: 27/06/2005 Warrant signed on 3586 receptor useful in the Company Road, Princeton, New Rec: 4572/4573 dt Vide PT 3586 Wef: 02/05/2006 11/01/2007 treatment of Att: MAMO TCV Advocates Jersey 08543-4000, 26/06/2006 thromboric conditions United States of America

Carbocycle & P.O. Box 4000, Route heterocycle Filing Date: 26/06/2006 Bristol-Myers Squibb 206 and Province Line antagonists of P 2 Y Rec: 4571/4570 dt Wef: 27/06/2005 Warrant signed on 3587 Company Road, Princeton, New Vide PT 3587 receptors useful in the 26/06/2006 11/01/2007 Att: MAMO TCV Advocates Jersey 08543-4000, treatment of United States of America thromboric conditions

Linear urea mimics P.O. Box 4000, Route antagonists of P2Y Bristol-Myers Squibb 206 and Province Line Filing Date: 26/06/2006 Warrant signed on 3588 receptor useful in the Company Road, Princeton, New Rec: 4567/4568 dt Wef: 27/06/2005 Vide PT 3588 11/01/2007 treatment of Att: MAMO TCV Advocates Jersey 08543-4000, 26/06/2006 thrombotic conditions United States of America

C-linked cyclic P.O. Box 4000, Route Filing Date: 26/06/2006 antagonists of P2Y Bristol-Myers Squibb 206 and Province Line Rec: 4564/4565 dt Warrant signed on 3589 receptor useful in the Company Road, Princeton, New 26/06/2006 Wef: 27/06/2005 Vide PT 3589 11/01/2007 treatment of Att: MAMO TCV Advocates Jersey 08543-4000, Claims Fee: Lm20 thrombotic conditions United States of America Rec 4566 of 26/06/2006

Wef: 27/06/2005 Wef: 27/06/2005 GlaxoSmithKline Filing Date: 26/06/2006 Immunagenic Rue de L' institut 89, B- Wef: 28/07/2005 Warrant signed on 3590 Biologicals s.a Rec: 4629/4630 dt Vide PT 3590 compositions 1330 Rixensart, Belgium Wef: 28/11/2005 11/01/2007 Att: SS & Co. 27/06/2006 Wef: 21/12/2005 Wef: 21/12/2005 Wef: 27/06/2005 Wef: 27/06/2005 GlaxoSmithKline Filing Date: 26/06/2006 Immunagenic Rue de L' institut 89, B- Wef: 28/07/2005 Warrant signed on 3591 Biologicals s.a Rec: 4632/4635 dt Vide PT 3591 compositions 1330 Rixensart, Belgium Wef: 28/11/2005 11/01/2007 Att: SS & Co. 27/06/2006 Wef: 21/12/2005 Wef: 21/12/2005

Wef: 27/06/2005 Wef: 27/06/2005 GlaxoSmithKline Filing Date: 26/06/2006 Immunagenic Rue de L' institut 89, B- Wef: 28/07/2005 Warrant signed on 3592 Biologicals s.a Rec: 4638/4639 dt Vide PT 3592 compositions 1330 Rixensart, Belgium Wef: 28/11/2005 11/01/2007 Att: SS & Co. 27/06/2006 Wef: 21/12/2005 Wef: 21/12/2005

Taissounieres HB4, 1681 route des Dolines, Nicox S.A & Pfizer Inc. BP313, 06560 Sophia Filing Date: 26/06/2006 Prostaglandin Att: SS & Co. Warrant signed on 3593 Antipolis -Valbonne, Rec: 4626/4627dt Wef: 29/06/2005 Vide PT 3593 derivatives 11/01/2007 France & 235 East 42nd 27/06/2006 Street, New York, New York 10017, USA

Janssen Pharmaceutica Filing Date: 26/06/2006 Cyclic Anilino - Turnhoutseweg 30, B- Warrant signed on 3594 N.V Rec: 4603/4604 dt Wef: 30/06/2005 Vide PT 3594 Pyridinotriazines 2340 Beerse, Belgium 11/01/2007 Att: EMD Advocates 26/06/2006

Janssen Pharmaceutica Filing Date: 26/06/2006 Quindine derivatives Turnhoutseweg 30, B- Warrant signed on 3595 N.V Rec: 4600/4601dt Wef: 28/06/2005 Vide PT 3595 as antibacterial agents 2340 Beerse, Belgium 11/01/2007 Att: EMD Advocates 26/06/2006

Janssen Pharmaceutica Filing Date: 26/06/2006 Quindine derivatives Turnhoutseweg 30, B- Warrant signed on 3596 N.V Rec: 4597/4598 dt Wef: 28/06/2005 Vide PT 3596 as antibacterial agents 2340 Beerse, Belgium 11/01/2007 Att: EMD Advocates 26/06/2006

Janssen Pharmaceutica Filing Date: 26/06/2006 Quindine derivatives Turnhoutseweg 30, B- Warrant signed on 3597 N.V Rec: 4593/4595 dt Wef: 28/06/2005 Vide PT 3597 as antibacterial agents 2340 Beerse, Belgium 11/01/2007 Att: EMD Advocates 26/06/2006

Niacin receptor agonists compositions 126 East Lincoln Filing Date: 26/06/2006 Merck & Co. Inc. Warrant signed on 3598 contains such Avenue, Rahway, NJ Rec: 4009/4010 dt Wef: 28/06/2005 Vide PT 3598 Att: CCA Interserv Ltd. 11/01/2007 compounds and 07065, USA 26/06/2006 methods of treatment 170 Harbor Way, PO Filing Date: 27/06/2006 Pyradole based LXR Exalixis Inc. Box 511, South San Wef: 27/06/2005 Warrant signed on 3599 Rec: 4674/4675 dt Vide PT 3599 modulators Att: J. Mifsud Francisco, California Wef: 10/11/2005 11/01/2007 28/06/2006 94083-0511, USA

170 Harbor Way, PO Filing Date: 27/06/2006 Imidazole based LXR Exalixis Inc. Box 511, South San Wef: 27/06/2005 Warrant signed on 3600 Rec: 4671/4672 dt Vide PT 3600 modulators Att: J. Mifsud Francisco, California Wef: 10/11/2005 11/01/2007 28/06/2006 94083-0511, USA

Aryl nitrile compounds One Amgen Centre and compositions and Filing Date: 27/06/2006 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3601 their use in treating Rec: 4677/4678 dt Wef: 27/06/2005 Vide PT 3601 Att: J. Mifsud California 91320 - 1799, 11/01/2007 inflammatory and 28/06/2006 USA related disorders

Smithkline Beecham One Franklin Plaza, PO Filing Date: 28/06/2006 Warrant signed on 3602 Chemical compounds Corporation Box 7929, Philadelphia, Rec: 4663/4664 dt Wef: 30/06/2005 Vide PT 3602 11/01/2007 Att: SS & Co. PA 19101, USA 28/06/2006

Non-Anilinic derivatives of isthiaz -3 Filing Date: 28/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3603 (2H) - one 1,1- dioxides Rec: 4600/4601 dt Wef: N/A Vide PT 3603 Att: SS & Co. Sweden 17/12/2007 as liver X receptor 28/06/2006 modulators

Anilinic derivatives of Filing Date: 28/06/2006 isothiazol-3 (2H) - one AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3604 Rec: 4657/4658 dt Wef: N/A Vide PT 3604 1,1 - dioxides as liver X Att: SS & Co. Sweden 17/12/2007 28/06/2006 receptor modulators

Case for receiving a Filing Date: 30/06/2006 Schering AG Warrant signed on 3605 medicament pack and Berlin 13342, Germany Rec: 4727/4728 dt Wef: 01/07/2005 Vide PT 3605 Att: MAMO TCV Advocates 10/10/2007 use thereof 03/07/2006

Filing Date: 30/06/2006 Optical imaging of Schering AG Mullerstrabe 170-178, Wef: 29/06/2005 Warrant signed on 3606 Rec: 4724/4725 dt Vide PT 3606 rheumatoid arthritis Att: MAMO TCV Advocates Berlin 13342, Germany Wef: 14/07/2005 11/01/2007 03/07/2006

Compositions containing magnetic Filing Date: 30/06/2006 iron oxide particles Schering AG Mullerstrabe 170-178, Warrant signed on 3607 Rec: 4721/4722 dt Wef: 29/06/2005 Vide PT 3607 and use of said Att: MAMO TCV Advocates Berlin 13342, Germany 11/01/2007 03/07/2006 compositions in imaging methods Compositions containing magnetic Filing Date: 30/06/2006 iron oxide particles Schering AG Mullerstrabe 170-178, Warrant signed on 3608 Rec: 4718/4719 dt Wef: 29/06/2005 Vide PT 3608 and use of said Att: MAMO TCV Advocates Berlin 13342, Germany 11/01/2007 03/07/2006 compositions in imaging methods

Pyrrolotriazine P.O. Box 4000, Route compounds useful as Bristol - Myers Squibb 206 and Province Line Filing Date: 30/06/2006 kinase inhibitors and Warrant signed on 3609 Company Road, Princeton, New Rec: 4715/4716 dt Wef: 01/07/2005 Vide PT 3609 methods of treating 10/10/2007 Att: MAMO TCV Advocates Jersey 08543-4000, 03/07/2006 kinase- associated United States of America conditions therwith

Pyrrolotriazine P.O. Box 4000, Route compounds useful as Bristol - Myers Squibb 206 and Province Line Filing Date: 30/06/2006 kinase inhibitors and Wef: 01/07/2005 Warrant signed on 3610 Company Road, Princeton, New Rec: 4712/4713 dt Vide PT 3610 methods of treating Wef: 08/02/2006 11/10/2007 Att: MAMO TCV Advocates Jersey 08543-4000, 03/07/2006 kinase- associated United States of America conditions therwith

Pyrrolotriazine P.O. Box 4000, Route compounds useful as Bristol - Myers Squibb 206 and Province Line Filing Date: 30/06/2006 Wef: 01/07/2005 kinase inhibitors and Warrant signed on 3611 Company Road, Princeton, New Rec: 4709/4710 dt Wef: 01/07/2005 Vide PT 3611 methods of treating 11/10/2007 Att: MAMO TCV Advocates Jersey 08543-4000, 03/07/2006 Wef: 28/07/2005 kinase- associated United States of America conditions therwith

Filing Date: 30/06/2006 AstraZeneca AB SE 15185 Sodertalje, Wef: 04/07/2005 Warrant signed on 3612 Chemical compounds Rec: 4730/4731 dt Vide PT 3612 Att: SS & Co. Sweden Wef: 08/03/2006 11/10/2007 03/07/2006

Filing Date: 30/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3613 Novel compounds II Rec: 4733/4734 dt Wef: 05/07/2005 Vide PT 3613 Att: SS & Co. Sweden 11/10/2007 03/07/2006

Filing Date: 30/06/2006 AstraZeneca AB SE 15185 Sodertalje, Warrant signed on 3614 Novel compounds II Rec: 4736/4737 dt Wef: 05/07/2005 Vide PT 3614 Att: SS & Co. Sweden 11/10/2007 03/07/2006

GlaxoSmithKline Filing Date: 30/06/2006 Consumers Healthcare Bussmatten 1, 77815 Warrant signed on 3615 Toothbrush Rec: 4739/4740 dt Wef: 01/07/2005 Vide PT 3615 GMBH & Co. KG Buehl, Germany 11/10/2007 03/07/2006 Att: SS & Co.

GlaxoSmithKline Rue de L' institut 89, B- Filing Date: 30/06/2006 Warrant signed on 3616 Vaccines Biologicals S.A 1330 Rixennsart, Rec: 4742/4743 dt Wef: 30/06/2005 Vide PT 3616 11/01/2007 Att: SS & Co. Belgium 03/07/2006 One Amgen Centre Filing Date: 30/06/2006 BIS- aryl kinase Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3617 Rec: 4746/4747 dt Wef: 30/06/2005 Vide PT 3617 inhibitors and methods Att: Dr. M. Chetcuti Cauchi California 91320 -1799, 11/01/2007 03/07/2006 USA

New 1H- indole- pyrimidine 12, Place De La Defense, 92415 carbboxamide and 1H- Les Laboratoires Servier Courbevoie Cedex, indole - piperidine & Centre National de la France & 3, Rue Michel Filing Date: 04/07/2006 carboxaminde Warrant signed on 3618 Recherche Scientifique & Ang, 75794 Paris Cedex Rec: 4791/4792 dt Wef: 07/07/2005 Vide PT 3618 compounds, a process 11/10/2007 Universite Paris Sud 16, France & 15, Rue 04/07/2006 on their preparation Att: SS & Co. Georges Clemenceau, and pharmaceutical 91405 Orsay Cedex, compositions France containing them MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Wef: 09/07/2005 Wef: 09/08/2005 Wef: AstraZeneca AB SE-151 85 Södertalje, Filing Date: 04/07/2006 Warrant signed on 3619 Chemical Compounds 24/11/2005 Wef: Vide PT 3619 Attn: SS & Co. Sweden Rec: 4794/5 dt 04/07/2006 11/10/2007 02/12/2005 Wef: 22/04/2006

Ramsgate Road, Pfizer Limited Filing Date: 04/07/2006 Wef: 08/07/2005 Warrant signed on 3620 Novel Madcam Antibodies Sandwich, Kent CT13 Vide PT 3620 Att: SS & Co. Rec: 4798/9 dt 04/07/2006 11/10/2007 9NJ, England

Sanofi-Pasteur 2 Avenue Pont, Filing Date: 04/07/2006 Wef: 07/07/2005 Warrant signed on 3621 Immuno-Aduvant Emulsion Vide PT 3621 Att: SS & Co. Pasteur, F 69007, Lyon Rec: 4801/3 dt 04/07/2006 Wef: 04/08/2005 11/10/2007

Modified Poly(propylene- imine) Dendrimers and Their Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 07/07/2006 Wef: 08/07/2005 Warrant signed on 3622 Use as Transfection Agents Vide PT 3622 Att: EMD Advocates 2340 Beerse, Belgium Rec: 4861 dt 07/07/2006 11/10/2007 for Anionic Bioactive Factors

Novartis AG Lichtstrasse 35, 4056 Filing Date: 07/07/2006 Warrant signed on 3623 Organic Compounds Wef: 11/07/2005 Vide PT 3623 Att: SS & Co. Basel, Switzerland Rec: 4873/4 dt 07/07/2006 11/10/2007

AstraZeneca AB SE-151 85 Södertalje, Filing Date: 07/07/2006 Warrant signed on 3624 Therapeutic Agents Wef: 11/07/2005 Vide PT 3624 Attn: SS & Co. Sweden Rec: 4885/6 dt 07/07/2006 11/10/2007

AstraZeneca AB SE-151 85 Södertalje, Filing Date: 07/07/2006 Wef: 13/07/2005 Warrant signed on 3625 New Pyridine Analogues Vide PT 3625 Attn: SS & Co. Sweden Rec: 4882/3 dt 07/07/2006 Wef: 24/10/2005 12/10/2007

Filing Date: 07/07/2006 Use of mGLUR5 (esp. Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3626 Rec: 4879/80 dt Wef: 12/07/2005 Vide PT 3626 AFQ056) in GI (esp. GERD) Att: SS & Co. Basel, Switzerland 12/10/2007 07/07/2006

Bicyclic Heteroaryl 505 Penobscot Drive, Genelabs Technologies Inc. Filing Date: 07/07/2006 Warrant signed on 3627 Derivatives for Treating Redwood City, CA Wef: N/A Vide PT 3627 Att: SS & Co. Rec: 4876/7 dt 07/07/2006 14/10/2008 Viruses 94063, U.S.A.

Kitanomaru Square 1- N-Dihydrosyalkyl- Banyu Pharmaceutical Co. Ltd. 13-12, Kudankita, Filing Date: 10/07/2006 Warrant signed on 3628 Substituted 2-oxo-Imidazole Att: Chetcuti Cauchi Advocates Wef: 13/07/2005 Vide PT 3628 Chiyoda-ku, Tokyo 102- Rec: 4934/5 dt 11/07/2006 12/10/2008 Derivatives 8667, Japan

PPARα/γ Agonists and Novartis AG Lichtstrasse 35, 4056 Filing Date: 11/07/2006 Warrant signed on 3629 Wef: 13/07/2005 Vide PT 3629 Processes of Preparing Att: SS & Co. Basel, Switzerland Rec: 4961/2 dt 11/07/2006 12/10/2007 Wef: 15/07/2005 Wef: 05/12/2005 Wef: Glaxo Wellcome House, 27/01/2006 Wef: Glaxo Group Limited Berkeley Avenue, Filing Date: 11/07/2006 Warrant signed on 3630 Novel Compounds 03/04/2006 Wef: Vide PT 3630 Att: SS & Co. Greenford, Middlesex Rec: 4967/8 dt 11/07/2006 12/10/2007 02/06/2006 Wef: UB6 0NN, Great Britain 09/06/2006 Wef: 26/05/2006

Wef: 15/07/2005 Wef: AstraZeneca AB SE-151 85 Södertalje, Filing Date: 11/07/2006 Warrant signed on 3631 Therapeutic Agents 24/08/2005 Wef: Vide PT 3631 Attn: SS & Co. Sweden Rec: 4964/5 dt 11/07/2006 12/10/2007 23/11/2005

New Derivatives of Heptaazaphenalene, Methods For Obtaining Isdin S.A. Av. Diagonal, 520, Filing Date: 12/07/2006 Warrant signed on 3633 Wef: 13/07/2005 Vide PT 3633 Them, and Their Use as Att: MAMO TCV Advocates 08006 Barcelona, Spain Rec: 4998/9 dt 12/07/2006 12/10/2007 Protecting Agents Against UV Radiation

126 East Lincoln Avenue, Rahway, NK Spiropiperidine Beta- Merck & Co. Inc. & Sunesis 07065-0907, U.S.A. & Secretase Inhibitors For The Filing Date: 13/07/2006 Warrant signed on 3634 Pharmaceuticals Inc. 341 Oyster Point Wef: 18/07/2005 Vide PT 3634 Treatment of Alzheimer's Rec: 5043/4 dt 14/07/2006 12/10/2007 Att: Chetcuti Cauchi Advocates Boulevard, South San Disease Francisco, CA 94080, U.S.A.

AstraZeneca AB SE-151 85 Södertalje, Filing Date: 14/07/2006 Warrant signed on 3635 Therapeutic Agents Wef: 19/07/2005 Vide PT 3635 Attn: SS & Co. Sweden Rec: 5040/1 dt 14/07/2006 12/10/2007

Perfluoroalkyl-Containing Müllerstraße 178, Berlin Schering AG & EPIX Complexes, Process for 13353, Germany & 161 Filing Date: 14/07/2006 Warrant signed on 3636 Pharmaceutical Inc. Wef: 15/07/2005 Vide PT 3636 Their Production as well as First Street, Cambridge Rec 5032/3 dt 14/07/2006 12/10/2007 Att: MAMO TCV Advocates Their Use MA 02142, U.S.A.

Perfluoroalkyl-Containing Müllerstraße 178, Berlin Schering AG & EPIX Complexes, Process for 13353, Germany & 161 Filing Date: 14/07/2006 Wef: 15/07/2005 Warrant signed on 3637 Pharmaceutical Inc. Vide PT 3637 Their Production as well as First Street, Cambridge Rec: 5037/8 dt 14/07/2006 Wef: 10/08/2005 12/10/2007 Att: MAMO TCV Advocates Their Use MA 02142, U.S.A.

4-Substituted Pyrazoline Laboratorios del Dr. Esteve S.A. Av. Mare de Déu de Compounds, Their Filing Date: 14/07/2006 Wef: 15/07/2005 Warrant signed on 3638 Att: Bezzina & Mifsud Montserrat, 221, E- Vide PT 3638 Preparation and Use as Rec: 5087/9 dt 18/07/2006 Wef: 05/08/2005 12/10/2007 Patentbureau 08041 Barcelona, Spain Medicaments Wef: 15/07/2005 Substituted Pyrazoline Wef: 05/08/2005 Laboratorios del Dr. Esteve S.A. Av. Mare de Déu de Compounds, Their Filing Date: 14/07/2006 Wef: 26/04/2006 Warrant signed on 3639 Att: Bezzina & Mifsud Montserrat, 221, E- Vide PT 3639 Preparation and Use as Rec: 5084/5 dt 18/07/2006 Wef: 26/04/2006 Wef: 12/10/2007 Patentbureau 08041 Barcelona, Spain Medicaments 26/04/2006 Wef: 26/04/2006

Substituted Pyrazoline Laboratorios del Dr. Esteve S.A. Av. Mare de Déu de Compounds, Their Filing Date: 14/07/2006 Wef: 15/07/2005 Warrant signed on 3640 Att: Bezzina & Mifsud Montserrat, 221, E- Vide PT 3640 Preparation and Use as Rec: 5081/2 dt 18/07/2006 Wef: 05/08/2005 12/10/2007 Patentbureau 08041 Barcelona, Spain Medicaments

Filing Date: 30/06/2006 Optical imaging of Schering AG Mullerstrabe 170-178, Wef: 29/06/2005 Warrant signed on 3641 Rec: 4724/4725 dt Vide PT 3641 rheumatoid arthritis Att: MAMO TCV Advocates Berlin 13342, Germany Wef: 14/07/2005 11/01/2007 03/07/2006

Compositions containing magnetic iron oxide Filing Date: 30/06/2006 Schering AG Mullerstrabe 170-178, Warrant signed on 3642 particles and use of said Rec: 4721/4722 dt Wef: 29/06/2005 Vide PT 3642 Att: MAMO TCV Advocates Berlin 13342, Germany 11/01/2007 compositions in imaging 03/07/2006 methods

Compositions containing magnetic iron oxide Filing Date: 30/06/2006 Schering AG Mullerstrabe 170-178, Warrant signed on 3643 particles and use of said Rec: 4718/4719 dt Wef: 29/06/2005 Vide PT 3643 Att: MAMO TCV Advocates Berlin 13342, Germany 11/01/2007 compositions in imaging 03/07/2006 methods

P.O. Box 4000, Route Pyrrolotriazine compounds 206 and Province Line useful as kinase inhibitors Bristol - Myers Squibb Filing Date: 30/06/2006 Road, Princeton, New Warrant signed on 3644 and methods of treating Company Rec: 4715/4716 dt Wef: 01/07/2005 Vide PT 3644 Jersey 08543-4000, 10/10/2007 kinase- associated Att: MAMO TCV Advocates 03/07/2006 United States of conditions therwith America

P.O. Box 4000, Route Pyrrolotriazine compounds 206 and Province Line useful as kinase inhibitors Bristol - Myers Squibb Filing Date: 30/06/2006 Road, Princeton, New Wef: 01/07/2005 Warrant signed on 3645 and methods of treating Company Rec: 4712/4713 dt Vide PT 3645 Jersey 08543-4000, Wef: 08/02/2006 11/10/2007 kinase- associated Att: MAMO TCV Advocates 03/07/2006 United States of conditions therwith America

P.O. Box 4000, Route Pyrrolotriazine compounds 206 and Province Line useful as kinase inhibitors Bristol - Myers Squibb Filing Date: 30/06/2006 Wef: 01/07/2005 Road, Princeton, New Warrant signed on 3646 and methods of treating Company Rec: 4709/4710 dt Wef: 01/07/2005 Vide PT 3646 Jersey 08543-4000, 11/10/2007 kinase- associated Att: MAMO TCV Advocates 03/07/2006 Wef: 28/07/2005 United States of conditions therwith America Filing Date: 30/06/2006 AstraZeneca AB SE-151 85 Södertalje, Wef: 04/07/2005 Warrant signed on 3647 Chemical compounds Rec: 4730/4731 dt Vide PT 3647 Attn: SS & Co. Sweden Wef: 08/03/2006 11/10/2007 03/07/2006

Filing Date: 30/06/2006 AstraZeneca AB SE-151 85 Södertalje, Warrant signed on 3648 Novel compounds II Rec: 4733/4734 dt Wef: 05/07/2005 Vide PT 3648 Attn: SS & Co. Sweden 11/10/2007 03/07/2006

Filing Date: 30/06/2006 AstraZeneca AB SE-151 85 Södertalje, Warrant signed on 3649 Novel compounds II Rec: 4736/4737 dt Wef: 05/07/2005 Vide PT 3649 Attn: SS & Co. Sweden 11/10/2007 03/07/2006

GlaxoSmithKline Biologicals Rue de L' institut 89, B- Filing Date: 30/06/2006 Warrant signed on 3651 Vaccines S.A 1330 Rixensart, Rec: 4742/4743 dt Wef: 30/06/2005 Vide PT 3651 11/01/2007 Att: SS & Co. Belgium 03/07/2006

One Amgen Centre Filing Date: 30/06/2006 BIS- aryl kinase inhibitors Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3652 Rec: 4746/4747 dt Wef: 30/06/2005 Vide PT 3652 and methods Att: Dr. M. Chetcuti Cauchi California 91320 - 1799, 11/01/2007 03/07/2006 USA

New 1H- indole- pyrimidine 12, Place De La carbboxamide and 1H- Defense, 92415 indole - piperidine Les Laboratoires Servier & Courbevoie, Cedex, carboxaminde compounds, Centre National de la France & 3, Rue Michel Filing Date: 04/07/2006 Warrant signed on 3654 a process on their Recherche Scientifique & Ang, 75794 Paris, Rec: 4791/4792 dt Wef: 07/07/2005 Vide PT 3654 11/10/2007 preparation and Universite Paris Sud Cedex 16, France & 15, 04/07/2006 pharmaceutical Att: SS & Co. Rue Georges compositions containing Clemenceau, 91405 them Orsay, Cedex, France New 1H- indole- pyrimidine 12, Place De La carbboxamide and 1H- Defense, 92415 indole - piperidine Les Laboratoires Servier & Courbevoie, Cedex, carboxaminde compounds, Centre National de la France & 3, Rue Michel Filing Date: 04/07/2006 Warrant signed on 3655 a process on their Recherche Scientifique & Ang, 75794 Paris, Rec: 4791/4792 dt Wef: 07/07/2005 Vide PT 3655 11/10/2007 preparation and Universite Paris Sud Cedex 16, France & 15, 04/07/2006 pharmaceutical Att: SS & Co. Rue Georges compositions containing Clemenceau, 91405 them Orsay, Cedex, France

Glaxo Wellcome House, Encapsulation of Lipid- Glaxo Group Limited Berkeley Avenue, Filing Date: 25/07/2006 Warrant signed on 3656 Based formulations in Wef: 26/07/2005 Vide PT 3656 Attn: SS & Co. Greenford, Middlesex Rec: 5290/1 dt 26/07/2006 23/11/2007 enteric polymers UB6 0NN, Great Britain

Tricyclic benzimidazoles and their use as metabotropic AstraZeneca AB SE-151 85 Södertalje, Filing Date: 25/07/2006 Warrant signed on 3657 Wef: 05/08/2005 Vide PT 3657 glutamate receptor Attn: SS & Co. Sweden Rec: 5293/4 dt 26/07/2006 01/04/2008 modulators

New Pyrido[3', 2': Ronda del General Almirall Prodesfarma S.A. Filing Date: 25/07/2006 Warrant signed on 3658 4,5]Furo[3,2-d] Pyrimidine Mitre 151, 08022 Wef: 27/07/2005 Vide PT 3658 Attn: SS & Co. Rec: 5296/7 dt 26/07/2006 23/11/2007 derivatives Barcelona, Spain

Eastgate Village, Tibotec Pharmaceuticals Ltd & Eastgate, Little Island, Macrocylic Inhibitors of Filing Date: 26/07/2006 Wef: 29/07/2005 Warrant signed on 3659 Medivir AB Co. Cork, Ireland & Vide PT 3659 Hepatitis C Virus Rec: 5268/9 dt 26/07/2006 Wef: 25/04/2006 23/11/2007 Attn: EMD Advocates Lunastigen 7, S-141 44 Huddinge, Sweden

Eastgate Village, Tibotec Pharmaceuticals Ltd & Eastgate, Little Island, Wef: 29/07/2005 Macrocylic Inhibitors of Filing Date: 26/07/2006 Warrant signed on 3660 Medivir AB Co. Cork, Ireland & Wef: 11/08/2005 Wef: Vide PT 3660 Hepatitis C Virus Rec: 5265/6 dt 26/07/2006 23/11/2007 Attn: EMD Advocates Lunastigen 7, S-141 44 03/02/2006 Huddinge, Sweden

Eastgate Village, Macrocylic Inhibitors of Tibotec Pharmaceuticals Ltd Filing Date: 26/07/2006 Wef: 29/07/2005 Warrant signed on 3661 Eastgate, Little Island, Vide PT 3661 Hepatitis C Virus Attn: EMD Advocates Rec: 5262/3 dt 26/07/2006 Wef: 11/08/2005 22/10/2007 Co. Cork, Ireland

Eastgate Village, Tibotec Pharmaceuticals Ltd & Eastgate, Little Island, Filing Date: 26/07/2006 Macrocylic Inhibitors of Wef: 29/07/2005 Warrant signed on 3662 Medivir AB Co. Cork, Ireland & Rec: 5259/60 dt Vide PT 3662 Hepatitis C Virus Wef: 03/02/2006 22/10/2007 Attn: EMD Advocates Lunastigen 7, S-141 44 26/07/2006 Huddinge, Sweden Filing Date: 26/07/2006 Antibacterial Quinoline Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3663 Rec: 5257/8 dt 26/07/2006 Wef: 28/07/2005 Vide PT 3663 Derivatives Attn: EMD Advocates 2340 Beerse, Belgium 22/10/2007

Zugerstrasse 8, CH- Filing Date: 26/07/2006 Process for Producing Galderma S.A. Warrant signed on 3664 6330 Cham, Rec: 5305/6 dt 26/07/2006 Wef: 28/07/2005 Vide PT 3664 Amorolfine Attn: SS & Co. 22/10/2007 Switzerland

Zugerstrasse 8, CH- Filing Date: 26/07/2006 Process for Producing Galderma S.A. Warrant signed on 3665 6330 Cham, Rec: 5307/8 dt 26/07/2006 Wef: 28/07/2005 Vide PT 3665 Bepromoline Attn: SS & Co. 22/10/2007 Switzerland

Ronda del General Filing Date: 26/07/2006 Laboratorios Almirall S.A. Warrant signed on 3666 New Pyrazine Derivatives Mitre 151, 08022 Rec: 5309/10 dt Wef: 29/07/2005 Vide PT 3666 Attn: SS & Co. 22/10/2007 Barcelona, Spain 26/07/2006

P.O. Box 4000, Route Substituted Tetrahydro-1H- 206 and Province Line Pyrido[4,3,B]Indoles as Bristol-Myers Squibb Company Filing Date: 28/07/2006 Warrant signed on 3667 Road, Princeton, New Wef: 28/07/2005 Vide PT 3667 Serotonin Receptor Attn: MAMO TCV Advocates Rec: 5352/3 dt 28/07/2006 22/10/2007 Jersey 08543-4000, Agonists and Antagonists U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 28/07/2006 Warrant signed on 3668 New Salt I Wef: 02/08/2005 Vide PT 3668 Attn: SS & Co. Sweden Rec: 5386/7 dt 31/07/2006 01/04/2008

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 28/07/2006 Warrant signed on 3669 New Salt II Wef: 02/08/05 Vide PT 3669 Attn: SS & Co. Sweden Rec: 5392/3 dt 31/07/2006 26/03/2008

Filing Date: 28/07/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3670 New Salt III Rec: 5389/90 dt Wef: 02/08/2005 Vide PT 3670 Attn: SS & Co. Sweden 07/04/2008 31/07/2006

Novel Process for the Medichem S.A. Pol. Ind. Celrà, 17460 Filing Date: 28/07/2006 Warrant signed on 3671 Production of Amorphous Wef: N/A Vide PT 3671 Attn: CC Advocates Celrà, Girona, Spain Rec: 5383/4 dt 31/07/2006 26/03/2008 Rabeprazole Sodium

P.O. Box 4000, Route Benzothiazole and 206 and Province Line Azabenzothiazole Bristol-Myers Squibb Company Filing Date: 01/08/2006 Warrant signed on 3672 Road, Princeton, New Wef: 01/08/2005 Vide PT 3672 Compounds Useful as Attn: MAMO TCV Advocates Rec: 5506/7 dt 07/08/2006 26/03/2008 Jersey 08543-4000, Kinase Inhibitors U.S.A. 130 Waverly Street, Filing Date: 01/08/2006 Inhibitors of Serine Vertex Pharmaceuticals Inc. Cambridge, Warrant signed on 3673 Rec: P5856/6 dt Wef: 02/08/2005 Vide PT 3673 Proteases Attn: EMD Advocates Massachusetts 02139- 07/04/2008 01/08/2006 4242, U.S.A.

Filing Date: 01/08/2006 Quinoline Derivatives as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3674 Rec: P5856/6 dt Wef: 03/08/2005 Vide PT 3674 Antibacterial Agents Attn: EMD Advocates 2340 Beerse, Belgium 09/06/2008 01/08/2006

Filing Date: 01/08/2006 Quinoline Derivatives as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3675 Rec: P5856/6 dt Wef: 03/08/2005 Vide PT 3675 Antibacterial Agents Attn: EMD Advocates 2340 Beerse, Belgium 23/10/2007 01/08/2006

Filing Date: 01/08/2006 Quinoline Derivatives as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3676 Rec: P5856/6 dt Wef: 03/08/2005 Vide PT 3676 Antibacterial Agents Attn: EMD Advocates 2340 Beerse, Belgium 23/10/2007 01/08/2006

New Camptothecine Analogue Compounds, a 12, Place de la process for their preparation Les Laboratoires Servier Defense, F-92415 Filing Date: 02/08/2006 Warrant signed on 3677 Wef: 05/08/2005 Vide PT 3677 and pharmaceutical Attn: SS & Co. Courbevoie Cedex, Rec: 5475/6 dt 07/08/2006 23/10/2007 compositions containing France them

New Camptothecine Analogue Compounds, a 12, Place de la process for their preparation Les Laboratoires Servier Defense, F-92415 Filing Date: 02/08/2006 Warrant signed on 3678 Wef: 05/08/2005 Vide PT 3678 and pharmaceutical Attn: SS & Co. Courbevoie Cedex, Rec: 5478/9 dt 07/08/2006 23/10/2007 compositions containing France them

New Crystalline Form III of 12, Place de la Agomelatine, a Process for Les Laboratoires Servier Defense, F-92415 Filing Date: 02/08/2006 Warrant signed on 3679 its preparation and Wef: 03/08/2005 Vide PT 3679 Attn: SS & Co. Courbevoie Cedex, Rec: 5481/2 dt 07/08/2006 23/10/2007 pharmaceutical France compositions containing it

New Crystalline Form IV of 12, Place de la Agomelatine, a Process for Les Laboratoires Servier Defense, F-92415 Filing Date: 02/08/2006 Warrant signed on 3680 its preparation and Wef: 03/08/2005 Vide PT 3680 Attn: SS & Co. Courbevoie Cedex, Rec: 5483/5 dt 07/08/2006 23/10/2007 pharmaceutical France compositions containing it

New Crystalline Form V of 12, Place de la Agomelatine, a Process for Les Laboratoires Servier Defense, F-92415 Filing Date: 02/08/2006 Warrant signed on 3681 its preparation and Wef: 03/08/2005 Vide PT 3681 Attn: SS & Co. Courbevoie Cedex, Rec: 5486/7 dt 07/08/2006 23/10/2007 pharmaceutical France compositions containing it Novartis AG Lichtstrasse 35, 4056 Filing Date: 02/08/2006 3682 Organic Compounds Wef: 05/08/2005 WITHDRAWN Vide PT 3682 Attn: SS & Co. Basel, Switzerland Rec: 5488/9 dt 07/08/2006

Eastern Point Road, Wef: 27/01/2006 PYY Agonists and uses Pfizer Products Inc. Filing Date: 02/08/2006 Warrant signed on 3683 Groton, Connecticut Wef: 30/01/2006 Wef: Vide PT 3683 thereof Attn: SS & Co. Rec: 5491/3 dt 07/08/2006 23/01/2008 06340, U.S.A. 27/01/2006

Bicyclic Piperazines as AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 02/08/2006 Warrant signed on 3684 Metabotropic Glutamate Wef: 15/08/2005 Vide PT 3684 Attn: SS & Co. Sweden Rec: 5496/7 dt 07/08/2006 23/10/2007 Receptor Antagonists

Acetylenic Piperazines as AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 02/08/2006 Warrant signed on 3685 Metabotropic Glutamate Wef: 15/08/2005 Vide PT 3685 Attn: SS & Co. Sweden Rec: 5500/1 dt 07/08/2006 23/10/2007 Receptor Antagonists

Substituted Piperazines as AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 02/08/2006 Warrant signed on 3686 Metabotropic Glutamate Wef: 15/08/2005 Vide PT 3686 Attn: SS & Co. Sweden Rec: 5503/4 dt 07/08/2006 25/10/2007 Receptor Antagonists

Pharmaceutical Form with sustained pH-independent Filing Date: 04/08/2006 active ingredient release for Schering AG Warrant signed on 3687 Berlin 13342, Germany Rec: 5509/10 dt Wef: 05/08/2005 Vide PT 3687 active ingredients having Attn: MAMO TCV Advocates 25/10/2007 07/08/2006 strong pH-dependent solubility

Novartis AG Lichtstrasse 35, 4056 Filing Date: 04/08/2006 Warrant signed on 3688 Liquid Formulations Wef: 09/08/2005 Vide PT 3688 Attn: SS & Co. Basel, Switzerland Rec: 5513/4 dt 07/08/2006 10/04/2008

Wef: 09/08/2005 AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 04/08/2006 Warrant signed on 3689 Novel Compounds Wef: 30/08/2005 Wef: Vide PT 3689 Attn: SS & Co. Sweden Rec: 5516/7 dt 07/08/2006 01/04/2008 08/03/2006

6-Membered Aryl and 505 Penobscot Drive, Filing Date: 04/08/2006 Genelabs Technologies Inc. Warrant signed on 3690 Heteroaryl Derivatives for Redwood City, CA Rec: 5519/20 dt Wef: 05/08/2005 Vide PT 3690 Attn: SS & Co. 25/06/2008 Treating Viruses 94063, U.S.A. 07/08/2006

Substituted Imidazole Novartis AG Lichtstrasse 35, 4056 Filing Date: 07/08/2006 Warrant signed on 3691 Compounds as KSP Wef: 09/08/2005 Vide PT 3691 Attn: Chetcuti Cauchi Advocates Basel, Switzerland Rec: 5572/3 dt 08/08/2006 09/04/2008 Inhibitors

One Amgen Center Amgen Inc. Filing Date: 07/08/2006 Pharmaceutical Drive, Thousand Oaks, Warrant signed on 3692 Attn: Bezzina & Mifsud Rec: 5569/70 dt Wef: 05/08/2005 Vide PT 3692 Formulations California 91320-1799, 12/06/2008 Patentbureau 08/08/2006 U.S.A. Novartis AG Lichtstrasse 35, 4056 Filing Date: 08/08/2006 Warrant signed on 3693 Organic Compounds Wef: 10/08/2005 Vide PT 3693 Attn: SS & Co. Basel, Switzerland Rec: 5553/4 dt 08/08/2006 25/10/2007

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 08/08/2006 Warrant signed on 3694 Amide Derivatives Wef: 12/08/2005 Vide PT 3694 Attn: SS & Co. Sweden Rec: 5565/6 dt 08/08/2006 25/10/2007

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 08/08/2006 Wef: 09/08/2005 Warrant signed on 3695 Compounds Vide PT 3695 Attn: SS & Co. Greenford, Middlesex Rec: 5562/3 dt 08/08/2006 Wef: 29/11/2005 25/10/2007 UB6 0NN, Great Britain

One Franklin Plaza, SmithKline Beecham Wef: 10/08/2005 P.O. Box 7929, Filing Date: 08/08/2006 Warrant signed on 3696 Novel Compounds Corporation Wef: 19/04/2006 Wef: Vide PT 3696 Philadelphia, PA 19101, Rec: 5559/6 dt 08/08/2006 25/10/2007 Attn: SS & Co. 21/07/2006 U.S.A.

Benzoate salt of 4-(5-methyl- Eastern Point Road, oxazolo[4,5-b]pyridin-2-yl)- Pfizer Products Inc. Filing Date: 08/08/2006 Warrant signed on 3697 Groton, Connecticut Wef: 08/08/2005 Vide PT 3697 1,4-diaza- Attn: SS & Co. Rec: 5556/7 dt 08/08/2006 25/10/2007 06340, U.S.A. bicyclo[3.2.2]nonane

Eastgate Village, Tibotec Pharmaceuticals Ltd. & Eastgate, Little Island, Filing Date: 08/08/2006 Warrant signed on 3698 HIV Protese Inhibitors Medivir AB Co. Cork, Ireland & Wef: 08/11/2005 Vide PT 3698 Rec: 5550/1 dt 08/08/2006 10/01/2008 Attn: EMD Advocates Lunastigen 7, S-141 44 Huddinge, Sweden

Ortho-Mcneil Pharmaceutical U.S. Route 202, Peptides and Compounds Filing Date: 08/08/2006 Warrant signed on 3699 Inc. Raritan, New Jersey Wef: 09/08/2005 Vide PT 3699 that bind to a receptor Rec: 5547/8 dt 08/08/2006 25/10/2007 Attn: EMD Advocates 08869, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 09/08/2006 Warrant signed on 3700 Therapeutic Agents Wef: 13/08/2005 Vide PT 3700 Attn: SS & Co. Sweden Rec: 5626/7 dt 09/08/2006 25/10/2007

Pharmaceutical Joint Stock Company Composition on Basis of 53 Krustpils st., LV- Filing Date: 09/08/2006 Warrant signed on 3701 "Grindeks" Wef: 15/08/2005 Vide PT 3701 Reverse Transcriptase 1057, Riga, Latvia Rec: 5690/1 dt 11/08/2006 25/10/2007 Attn: Chetcuti Cauchi Advocates Inhibitor and Meldonium

Schering AG Filing Date: 10/08/2006 Warrant signed on 3702 Acyltruptophanols Berlin 13342, Germany Wef: 10/08/2005 Vide PT 3702 Attn: MAMO TCV Advocates Rec: 5692 dt 11/08/2006 25/10/2007 Film-coated tablet or granules containing as active ingredient a Siegfried Generics International Untere Brühlstrasse 4, Filing Date: 11/08/2006 Warrant signed on 3703 pyridylpyrimidine compound AG Zofingen CH-4800, Wef: 15/08/2005 Vide PT 3703 Rec: 5703/4 dt 14/08/2006 25/10/2007 or a pharmaceutically Attn: MAMO TCV Advocates Switzerland acceptable salt of this compound

One Amgen Center Filing Date: 11/08/2006 Amgen Inc. Wef: 12/08/2005 Warrant signed on 3704 Modified Fc Molecules Drive, Thousand Oaks Rec: 5728/30 dt Vide PT 3704 Attn: Chetcuti Cauchi Advocates Wef: 10/08/2006 25/10/2007 91320, U.S.A. 14/08/2006

One Amgen Center Bis-Aryl Amide Compounds Amgen Inc. Filing Date: 14/08/2006 Wef: 15/08/2005 Warrant signed on 3705 Drive, Thousand Oaks Vide PT 3705 and Methods of Use Attn: Chetcuti Cauchi Advocates Rec: 5722/3 dt 14/08/2006 Wef: 11/08/2006 25/10/2007 91320, U.S.A.

Filing Date: 14/08/2006 Benzoquinazoline Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3706 Rec: 5749/50 dt Wef: 15/08/2005 Vide PT 3706 Derivatives Attn: SS & Co. Basel, Switzerland 22/10/2007 16/08/2006

57 St Christopher Street, Valletta VLT 08, Arrow International Limited & Malta & 83 Jiefang Crystalline Sodium Zhejiang Neo-Dankong Filing Date: 14/08/2006 Wef: 15/08/2005 Warrant signed on 3707 North Road, Jiaojiang Vide PT 3707 Atorvastatin Pharmaceutical Co Ltd Rec: 5740/1 dt 16/08/2006 Wef: 07/07/2006 23/11/2007 District of Taizhou, Attn: SS & Co. Zhejiang Prov 318000, China

57 St Christopher Street, Valletta VLT 08, Arrow International Limited & Malta & 83 Jiefang Crystalline Sodium Zhejiang Neo-Dankong Filing Date: 14/08/2006 Wef: 15/08/2005 Warrant signed on 3708 North Road, Jiaojiang Vide PT 3708 Atorvastatin Pharmaceutical Co Ltd Rec: 5743/4 dt 16/08/2006 Wef: 07/07/2006 23/11/2007 District of Taizhou, Attn: SS & Co. Zhejiang Prov 318000, China

P.O. Box 4000, Route 206 and Province Line Factor Xa Inhibitor Bristol-Myers Squibb Company Filing Date: 16/08/2006 Wef: 17/08/2005 Warrant signed on 3709 Road, Princeton, New Vide PT 3709 Formulation and Method Attn: MAMO TCV Advocates Rec: 5737/8 dt 16/08/2006 Wef: 15/08/2006 22/10/2007 Jersey 08543-4000, U.S.A.

Solid Dosage Forms of Filing Date: 16/08/2006 Valsartan and Amlodipine Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3710 Rec: 5779/80 dt Wef: 17/08/2005 Vide PT 3710 and Method of Making the Attn: SS & Co. Basel, Switzerland 22/10/2007 17/08/2006 Same Filing date: 16/08/2006 GlaxoSmithKline Biologicals Rue de l'Institut 89, B- Wef: 17/08/05 Wef: Rec 5782/3 of 17/08/2006 Warrant signed on 3711 Vaccine s.a. 1330 Rixensart, 18/10/05 Wef: Vide PT 3711 Claims Fee: LM130 22/10/2007 Attn: SS & Co. Belgium 05/05/06 Rec 5784 of 17/08/2006

100 Philips Parkway, Memory Pharmaceuticals Corp Montvale, NJ 07645, Phosphodiesterase 10 & Amgen Inc. U.S.A. & One Amgen Filing Date: 16/08/2006 Wef: 16/08/2005 Warrant signed on 3712 Vide PT 3712 Inhibitors Attn: Bezzina & Mifsud Center Drive, Thousand Rec: 5776/7 dt 17/08/2006 Wef: 22/09/2005 22/10/2007 Patentbureau Oaks, CA 91320-1799, U.S.A.

Solid Pharmaceutical Composition comprising 1- Novartis AG Lichtstrasse 35, 4056 Filing Date: 18/08/2006 Warrant signed on 3713 (4-chloroanilino)-4-(4- Wef: 22/08/2005 Vide PT 3713 Attn: SS & Co. Basel, Switzerland Rec: 5841/2 dt 21/08/2006 22/10/2007 pyridylmethyl)phthalazine and a pH modifier

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 18/08/2006 Warrant signed on 3714 Novel Compounds Wef: 29/08/2005 Vide PT 3714 Attn: SS & Co. Sweden Rec: 5847/8 dt 21/08/2006 16/11/2007

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 18/08/2006 Wef: 26/08/2005 Warrant signed on 3715 New Combination Vide PT 3715 Attn: SS & Co. Sweden Rec: 5844/5 dt 21/08/2006 Wef: 01/06/2006 22/10/2007

Novel Use of Peptide Alfred-Nobel-Str. 10, Wef: 18/08/2005 Schwarz Pharma AG Filing Date: 18/08/2006 Warrant signed on 3716 Compounds for Treating 40789 Monheim, Wef: 08/06/2006 Vide PT 3716 Attn: GS Services Limited Rec: 5894/5 dt 23/08/2006 22/10/2007 Muscle Pain Germany Wef: 08/06/2006

130 Waverly Street, Vertex Pharmaceuticals Processes and Cambridge, Filing Date: 18/08/2006 Wef: 19/08/2005 Warrant signed on 3717 Incorporation Vide PT 3717 Intermediates Massachusetts 02139- Rec: 5816/7 dt 18/08/2006 Wef: 01/06/2006 22/10/2007 Attn: EMD Advocates 4242, U.S.A.

Tetrahydroquinolines and Merz Pharma GmbH & Co. 100 Eckenheimer their use as Modulators of Filing Date: 18/08/2006 Warrant signed on 3718 KGAA Landstrasse, D-60318 Wef: 24/08/2005 Vide PT 3718 Metabotropic Glutamate Rec: 5838/9 dt 21/08/2006 22/10/2007 Attn: CC Advocates Frankfurt, Germany Receptors

Pyrazolopyridine and One Amgen Center Filing Date: 21/08/2006 Amgen Inc. Wef: 22/08/2005 Warrant signed on 3719 Pyrazolopyrimidine Drive, Thousand Oaks Rec: 5889/90 dt Vide PT 3719 Attn: CC Advocates Wef: 07/09/2005 22/10/2007 Compounds 91320, U.S.A. 23/08/2006 MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Novartis AG Lichtstrasse 35, 4056 Filing Date: 22/08/2006 Warrant signed on 3720 Organic Compounds Wef: 25/08/2005 Vide PT 3720 Attn: SS & Co. Basel, Switzerland Rec: 5973 dt 28/08/2006 22/10/2007

One Amgen Center Amgen Inc. Filing Date: 22/08/2006 Wef: 31/08/2005 Warrant signed on 3721 Polypeptides and Antibodies Drive, Thousand Oaks, Vide PT 3721 Att: SS & Co. Rec: 5981/2 dt 28/08/2006 Wef: 31/08/2005 16/10/2007 CA 91320, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/08/2006 Wef: 29/08/2005 Warrant signed on 3722 Novel Compounds Vide PT 3722 Attn: SS & Co. Sweden Rec: 5984/5 dt 28/08/2006 Wef: 15/06/2006 16/11/2007

6-10, Koishikawa 4- Novel Pyridine Derivatives and Eisai R&D Management Co. Ltd. Filing Date: 22/08/2006 Wef: 24/08/2005 Warrant signed on 3723 chome, Bunkyo-ku, Vide PT 3723 Pyrimidine Derivatives (3) Attn: SS & Co. Rec: 5987/8 dt 28/08/2006 22/10/2007 Tokyo 112-8088, Japan

The Trustees of Columbia 412 Low Memorial Agents for Preventing and University in the City of New Library, 535 W. 116th Filing Cate: 22/08/2006 Wef: 25/08/2005 Warrant signed on 3724 Treating Disorders Involving Vide PT 3724 York Street, New York, Rec: 5970/1 dt 28/08/2006 22/10/2007 Modulation of the RYR Receptors Attn: SS & Co. NY10027, U.S.A.

60 Hampshire Street, Idenix Pharmaceuticals Inc & Cambridge, MA 02139 Seven-Membered Ring Centre National De La Recherce Filing Date: 23/08/2006 Wef: 23/08/2005 Warrant signed on 3725 & 3, rue Michel-Ange, F- Vide PT 3725 Nucleosides Scientifique Rec: 5946 dt 25/08/2006 22/10/2007 75794 Paris Cedex 16, Attn: CC Advocates France

60 Hampshire Street, Idenix Pharmaceuticals Inc & Cambridge, MA 02139 Novartis AG & The Chancellors, & Lichtstrasse 35, 4056 Process for Preparing Filing Date: 25/08/2006 Wef: 26/08/2005 Warrant signed on 3726 Masters and Scholars of the Basel, Switzerland & Vide PT 3726 Saccharinic Acids and Lactones Rec: 5965/6 dt 28/08/2006 22/10/2007 Univeristy of Oxford Wellington Square, Attn: CC Advocates Oxford OX1 2JD, England

Novartis AG Lichtstrasse 35, 4056 Filing Date: 25/08/2006 Warrant signed on 3727 Liposome Compositions Wef: 01/09/2005 Vide PT 3727 Attn: SS & Co. Basel, Switzerland Rec: 5961/2 dt 25/08/2006 16/11/2007

One Franklin Plaza, SmithKline Beecham Filing Date: 25/08/2006 Pyrimidinyl-Pyrazole Inhibitors of P.O. Box 7929, Wef: 26/08/2005 Warrant signed on 3728 Corporation Rec: 5959/60 dt Vide PT 3728 Aurora Kinases Philadelphia, PA 19101, 22/10/2007 Attn: SS & Co. 25/08/2006 U.S.A. 327 Cambridge Science KuDOS Pharmaceuticals Park, Milton Road, Filing Date: 25/08/2006 Warrant signed on 3729 ATM Inhibitor Limited Wef: 31/08/2005 Vide PT 3729 Cambridge CB4 0WG, Rec: 5978/9 dt 28/08/2006 16/11/2007 Attn: SS & Co. U.K.

130 Waverly Street, Vertex Pharmaceuticals Cambridge, Filing Date: 25/08/2006 Warrant signed on 3730 Inhibitors of Serine Proteases Incorporated Wef: 26/08/2005 Vide PT 3730 Massachusetts 02139- Rec: 5991/2 dt 28/08/2006 03/03/2008 Attn: EMD Advocates 4242, U.S.A.

One Franklin Plaza, SmithKline Beecham Benzimidazole Thiophene P.O. Box 7929, Filing Date: 28/08/2006 Wef: 06/09/2005 Warrant signed on 3731 Corporation Vide PT 3731 Compounds Philadelphia, PA 19101, Rec: 6042/3 dt 30/08/2006 Wef: 27/03/2006 15/11/2007 Attn: SS & Co. U.S.A.

Waidhausenstraße Method for Producing Bank Ing. Mag. Friedrich Sustr. Filing Date: 29/08/2006 Warrant signed on 3732 26a/1/3, A-1140 Wef: 01/09/2005 Vide PT 3732 Notes Attn: SS & Co. Rec: 6006/7 dt 29/08/2006 15/11/2007 Vienna, Austria

Solid Particulate Tadalafil having Teva Pharmaceutical Industries 5 Basel Street, P.O. Filing Date: 29/08/2006 Warrant signed on 3733 a Bimodal Particle Size Ltd. Box 3190, Petah Tiqva Rec: 6039/40 dt Wef: 29/08/2005 Vide PT 3733 15/11/2007 Distribution Attn: CC Advocates 49131, Israel 30/08/2006

One Amgen Center Drive, Thousand Oaks, California 91320-1799, U.S.A. & 80 Limewood Amgen Inc. & John Peter Geibel Wef: 02/09/2005 Methods of Modulating Intestinal Avenue, Branford, Filing Date: 29/08/2006 Warrant signed on 3734 & Steven Charles Hebert Wef: 04/04/2006 Vide PT 3734 Fluid Balance Connecticut 06405, Rec: 6036/7 dt 30/08/2006 15/11/2007 Attn: CC Advocates U.S.A. & 24 Timber Lane, Woodbridge, Connecticut 06525, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 30/08/2006 Wef: 06/09/2005 Warrant signed on 3735 Novel Compounds Vide PT 3735 Attn: SS & Co. Sweden Rec: 6032/3 dt 30/08/2006 15/11/2007

Wef: 30/08/2005 Substituted Benzimidazoles and Wef: 30/08/2005 Methods of Their Use as Novartis AG Lichtstrasse 35, 4056 Filing Date: 30/08/2006 Warrant signed on 3736 Wef: 27/10/2005 Vide PT 3736 Inhibitors of Kinases associated Attn: CC Advocates Basel, Switzerland Rec: 6055/6 dt 31/08/2006 15/11/2007 Wef: 17/02/2006 with Tumorigenesis

Wef: 30/08/2005 Wef: 30/08/2005 Substituted Benzimidazoles and Novartis AG Lichtstrasse 35, 4056 Filing Date: 30/08/2006 Warrant signed on 3737 Wef: 27/10/2005 Vide PT 3737 Methods of Preparation Attn: CC Advocates Basel, Switzerland Rec: 6052/3 dt 31/08/2006 15/11/2007 Wef: 17/02/2006 Glaxo Wellcome House, Novel Cysteine Protease Glaxo Group Limited Berkeley Avenue, Filing Date: 01/09/2006 Wef: 02/09/2005 Warrant signed on 3738 Vide PT 3738 Inhibitors Attn: SS & Co. Greenford, Middlesex, Rec: 6100/1 dt 01/09/2006 Wef: 03/03/2006 15/11/2007 UB6 0NN, Great Britain

Glaxo Wellcome House, Novel Cysteine Protease Glaxo Group Limited Berkeley Avenue, Filing Date: 01/09/2006 Wef: 02/09/2005 Warrant signed on 3739 Vide PT 3739 Inhibitors Attn: SS & Co. Greenford, Middlesex, Rec: 6097/8 dt 01/09/2006 Wef: 03/03/2006 15/11/2007 UB6 0NN, Great Britain

Depigmenting Composition for the Skin, comprising adapalene, Galderma Research & 2400 Route des Colles, Filing Date: 01/09/2006 Warrant signed on 3740 at least one depigmenting agent Development S.N.C. Les Templiers 06410 Wef: 02/09/2005 Vide PT 3740 Rec: 6095/6 dt 01/09/2006 15/11/2007 and at least one anti- Attn: SS & Co. BIOT, France inflammatory agent

One Franklin Plaza, SmithKline Beecham Filing Date: 05/09/2006 P.O. Box 7929, Wef: 09/09/2005 Warrant signed on 3741 Novel Compounds Corporation Rec: 6179/81 dt Vide PT 3741 Philadelphia, PA 19101, Wef: 06/06/2006 15/11/2007 Attn: SS & Co. 06/09/2006 U.S.A.

Treatment of Autoimmune Novartis AG Lichtstrasse 35, 4056 Filing Date: 05/09/2006 Wef: 09/09/2005 Warrant signed on 3742 Vide PT 3742 Diseases Attn: SS & Co. Basel, Switzerland Rec: 6176/7 dt 06/09/2006 15/11/2007

6701 Kaiser Drive, Fremont 94555, Amgen Fremont Inc. & Pfizer Human Monoclonal Antibodies to California, U.S.A. & 235 Filing Date: 06/09/2006 Wef: 07/09/2005 Warrant signed on 3744 Inc. Vide PT 3744 Activin Receptor-Like Kinase-1 East 42nd Street, New Rec: 6215/6 dt 07/09/2006 15/11/2007 Attn: SS & Co. York 10017, New York, U.S.A.

New Association Between 12, Place De La Agomelatine and a Noradrenaline Les Laboratoires Servier Defense, F-92415 Filing Date: 06/09/2006 Wef: 09/09/2005 Warrant signed on 3745 Reuptake Inhibitor and Vide PT 3745 Attn: SS & Co. Courbevoie Cedex, Rec: 6218/9 dt 07/09/2006 15/11/2007 Pharmaceutical Compositions France Containing It

Use of Agomelatine in Obtaining 12, Place De La Medicaments Intended for the Les Laboratoires Servier Defense, F-92415 Filing Date: 06/09/2006 Wef: 09/09/2005 Warrant signed on 3746 Vide PT 3746 Treatment of Sleep Disorders in Attn: SS & Co. Courbevoie Cedex, Rec: 6220/1 dt 07/09/2006 15/11/2007 the Depressed Patient France New Association Between 12, Place De La Agomelatine and a Les Laboratoires Servier Defense, F-92415 Filing Date: 06/09/2006 Wef: 09/09/2005 Warrant signed on 3747 Thymoregulatory Agent, and Vide PT 3747 Attn: SS & Co. Courbevoie Cedex, Rec: 6222/3 dt 07/09/2006 15/11/2007 Pharmaceutical Compositions France Containing It

4 Willsborough Cluster, Selamine Limited Clonhaugh Industrial Filing Date: 06/09/2006 Warrant signed on 3748 Ramipril Formulation Wef: 06/09/2005 Vide PT 3748 Attn: SS & Co. Estate, Dublin, Ireland Rec: 6224/6 dt 07/09/2006 15/11/2007 17

P.O. Box 4000, Route 206 and Province Line Bristol-Myers Squibb Company Filing Date: 06/09/2006 Wef: 09/09/2005 Warrant signed on 3749 Acyclic Ikur Inhibitors Road, Princeton, New Vide PT 3749 Attn: MAMO TCV Advocates Rec: 6228/9 dt 07/09/2006 15/11/2007 Jersey 08543-4000, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 07/09/2006 Warrant signed on 3750 Therapeutic Agents Wef: 15/09/2005 Vide PT 3750 Attn: SS & Co. Sweden Rec: 6231 dt 07/09/2006 15/11/2007

P.O. Box 4000, Route Cyclopropyl Fused 206 and Province Line Wef: 12/09/2005 Bristol-Myers Squibb Company Filing Date: 12/09/2006 Warrant signed on 3751 Indolobenzazepine HCV NS5B Road, Princeton, New Wef: 01/06/2006 Vide PT 3751 Attn: MAMO TCV Advocates Rec: 6290/1 dt 12/09/2006 15/11/2007 Inhibitors Jersey 08543-4000, Wef: 22/08/2006 U.S.A.

P.O. Box 4000, Route 206 and Province Line Indolobenzazepine HCV NS5B Bristol-Myers Squibb Company Filing Date: 12/09/2006 Wef: 13/09/2005 Warrant signed on 3752 Road, Princeton, New Vide PT 3752 Inhibitors Attn: MAMO TCV Advocates Rec: 6293/4 dt 12/09/2006 Wef: 08/02/2006 12/11/2007 Jersey 08543-4000, U.S.A.

Novel Lysine Salts of 4- Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Sate: 12/09/2006 Warrant signed on 3753 ((Phenoxyalkyl)thioi)- Wef: 14/09/2005 Vide PT 3753 Attn: EMD Advocates 2340 Beerse, Belgium Rec: 6287/8 sr 12/09/2006 12/11/2007 Phenoxyacetic Acid Derivatives

2-Aniline-4-Aryl Substituted Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 12/09/2006 Warrant signed on 3754 Wef: 13/09/2005 Vide PT 3754 Thiazole Derivatives Attn: EMD Advocates 2340 Beerse, Belgium Rec: 6284/5 dt 12/09/2006 12/11/2007

SE-151 85 Sodertalje, AstraZeneca AB & Dainippon Sweden & 6-8, Dosho- Filing Date: 12/09/2006 Wef: 16/09/2005 Warrant signed on 3755 Novel Compounds Sumitomo Pharma Co. Ltd Vide PT 3755 machi 2-chome, Chuo- Rec: 6315/6 dt 12/09/2006 Wef: 19/09/2005 12/11/2007 Attn: SS & Co. ku, Osaka-shi, Japan AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 12/09/2006 Warrant signed on 3756 Novel Compounds Wef: 19/09/2005 Vide PT 3756 Attn: SS & Co. Sweden Rec: 6312/3 dt 12/09/2006 12/11/2007

Filing Date: 12/09/2006 Combinations comprising a Novartis AG Lichtstrasse 35, 4056 Wef: 13/09/2005 Warrant signed on Rec: 6309/10 dt Vide PT 3757 VEGF Receptor Inhibitor Attn: SS & Co. Basel, Switzerland Wef: 13/09/2005 12/11/2007 12/09/2006

64 Av. De la Roseraie, NovImmune S.A. Filing Date: 12/09/2006 Warrant signed on 3758 Anti-CD3 Antibody Formulations Geneva, CH-1211, Wef: 12/09/2005 Vide PT 3758 Attn: SS & Co. Rec: 6306/7 dt 12/09/2006 12/11/2007 Switzerland

Wef: 13/09/2005 Wef: 19/12/2005 Processes for the Synthesis of Sicor Inc. 19 Hughes, Irvine, Filing Date: 13/09/2006 Warrant signed on 3759 Wef: 20/12/2005 Vide PT 3759 Rocuronium Bromide Attn: CC Advocates California 92618, U.S.A. Rec: 6360/1 dt 14/09/2006 14/11/2007 Wef: 23/02/2006 Wef: 21/03/2006

Metered Dispensing Valve Lesaffre et Compagnie 41 rue Etienne Marcel, Filing Date: 13/09/2006 Wef: 13/09/2005 Warrant signed on 3760 Comprising a Fixed Inner Pipe Vide PT 3760 Attn: CC Advocates 75001 Paris, France Rec: 6356/7 dt 14/09/2006 Wef: 23/06/2006 23/01/2008 and a Movable outer Sleeve

Wef: 13/09/2005 Wef: 19/12/2005 Sicor Inc. 19 Hughes, Irvine, Filing Date: 13/09/2006 Warrant signed on 3761 Pure Rocuronium Bromide Wef: 20/12/2005 Vide PT 3761 Attn: CC Advocates California 92618, U.S.A. Rec: 6353/4 dt 14/09/2006 14/11/2007 Wef: 23/02/2006 Wef: 21/03/2006

Conformationally Constrained 3- One Amgen Center (4-Hydroxy-Phenyl)-Substituted- Amgen Inc. Drive, Thousand Oaks, Filing Date: 14/09/2006 Warrant signed on 3762 Wef: 14/09/2005 Vide PT 3762 Propanoic Acids Useful for Attn: CC Advocates California 91320-1799, Rec: 6396/7 dt 15/09/2006 25/06/2008 Treating Metabolic Disorders U.S.A.

Ramsgate Road, Wef: 21/09/2005 Carboxamide derivatives as Pfizer Limited Filing Date: 15/09/2006 Warrant signed on 3763 Sandwich, Kent CT13 Wef: 21/09/2005 Vide PT 3763 Muscarinic Receptor Antagonists Attn: SS & Co. Rec: 6378/9 dt 15/09/2006 03/09/2008 9NJ, England Wef: 21/09/2005

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 15/09/2006 Warrant signed on 3764 Alkylnitrile Quinolines Wef: 21/09/2005 Vide PT 3764 Attn: SS & Co. Sweden Rec: 6393/4 dt 15/09/2006 07/04/2008

SE-151 85 Sodertalje, AstraZeneca AB & Dainippon Sweden & 6-8, Dosho- Filing Date: 15/09/2006 Warrant signed on 3765 Novel Compounds Sumitomo Pharma Co. Ltd. Wef: 22/09/2005 Vide PT 3765 machi 2-chome, Chuo- Rec: 6390/1 dt 15/09/2006 01/04/2008 Attn: SS & Co. ku, Osaka-shi, Japan AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 15/09/2006 Wef: 21/09/2005 Warrant signed on 3766 Alkyl Sulfoxide Quinolines Vide PT 3766 Attn: SS & Co. Sweden Rec: 6387/8 dt 15/09/2006 Wef: 21/09/2005 14/11/2007

Wef: 20/09/2005 AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 15/09/2006 Warrant signed on 3767 Chemical Compounds Wef: 02/12/2005 Vide PT 3767 Attn: SS & Co. Sweden Rec: 6384/5 dt 15/09/2006 14/11/2007 Wef: 07/04/2006

Compositions comprising at least one naphthoic acid derivative and at least one Galderma Research & 2400 Route des Colles, Filing Date: 18/09/2006 Warrant signed on 3769 compound of polyurethane Development S.N.C. Les Templiers 06410 Rec: 6439/40 dt Wef: 16/09/2005 Vide PT 3769 14/11/2007 polymer type or derivatives Attn: SS & Co. BIOT, France 18/09/2006 thereof, preparation processes therefore and uses thereof

4 Willsborough Cluster, Selamine Limited Clonshaugh Industrial Filing Date: 18/09/2006 Wef: 16/09/2005 Warrant signed on 3770 Bisphosphonate Formulation Vide PT 3770 Attn: SS & Co. Estate, Dublin 17, Rec: 6442 dt 18/09/2006 Wef: 24/05/2006 14/11/2007 Ireland

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/09/2006 Warrant signed on 3771 New Compounds I Wef: 29/09/2005 Vide PT 3771 Attn: SS & Co. Sweden Rec: 6470/1 dt 19/09/2006 14/11/2007

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/09/2006 Warrant signed on 3772 New Compounds II Wef: 29/09/2005 Vide PT 3772 Attn: SS & Co. Sweden Rec: 6467/8 dt 19/09/2006 14/11/2007

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/09/2006 Warrant signed on 3773 Chemical Compound Wef: 30/09/2005 Vide PT 3773 Attn: SS & Co. Sweden Rec: 6465/6 dt 19/09/2006 14/11/2007

Imidazole Compounds for the Eastern Point Road, Pfizer Products Inc. Filing Date: 19/09/2006 Warrant signed on 3774 Treatment of neurological Groton, Connecticut Wef: 22/09/2005 Vide PT 3774 Attn: SS & Co. Rec: 6462/3 dt 19/09/2006 14/11/2007 disorders 06340, U.S.A.

Filing Date: 19/09/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3775 Chemical Process Rec: 6459/60 dt Wef: 30/09/2005 Vide PT 3775 Attn: SS & Co. Sweden 14/11/2007 19/09/2006

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/09/2006 Warrant signed on 3776 Chemical Compounds Wef: 30/09/2005 Vide PT 3776 Attn: SS & Co. Sweden Rec: 6456/7 dt 19/09/2006 14/11/2007

Crystalline Forms of the Di- 765 Old Saw Mill River sodium Salt of N-(5- Emisphere Technologies Inc. Filing Date: 19/09/2006 Warrant signed on 3777 Road, Tarrytown, New Wef: 19/09/2005 Vide PT 3777 Chlorosalicyloyl)-8-aminocaprylic Attn: MAMO TCV Advocates Rec: 6500/1 dt 22/09/2006 14/11/2007 York 10591, U.S.A. Acid New Compounds for the AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/09/2006 Warrant signed on 3778 treatment of neurological, Wef: 29/09/2005 Vide PT 3778 Attn: SS & Co. Sweden Rec: 6512/3 dt 22/09/2006 01/04/2008 psychiatric or pain disorders

SmithKline Beecham (Cork) Currabinny, Carrigaline, Method of Improvement of Filing Date: 20/09/2006 Wef: 22/09/2005 Warrant signed on 3779 Limited Co. Cork, Republic of Vide PT 3779 Cognitive Function Rec: 6503/4 dt 22/09/2006 Wef: 17/10/2005 25/06/2008 Attn: SS & Co. Ireland

Pharmaceutical Composition for SmithKline Beecham (Cork) Currabinny, Carrigaline, Filing Date: 20/09/2006 Wef: 22/09/2005 Warrant signed on 3780 Improvement of Cognitive Limited Co. Cork, Republic of Rec: 6509/10 dt Vide PT 3780 Wef: 17/10/2005 10/01/2008 Function Attn: SS & Co. Ireland 22/09/2006

One Franklin Plaza, SmithKline Beecham P.O. Box 7929, Filing Date: 20/09/2006 Wef: 23/09/2005 Warrant signed on 3781 Compounds Corporation Vide PT 3781 Philadelphia, PA 19101, Rec: 6506/7 dt 22/09/2006 Wef: 17/03/2006 26/03/2008 Attn: SS & Co. U.S.A.

Oral Administration of N-(2- P.O. Box 4000, Route chloro-6-methylphenyl)-2-[[6-[4-(2- 203 and Province Line Wef: 21/09/2005 hydroxyethyl)-1-piperazinyl]-2- Bristol-Myers Squibb Company Filing Date: 20/09/2006 Warrant signed on 3782 Road, Princeton, New Wef: 01/06/2006 Vide PT 3782 methyl-4-pyrimidinyl]amino]1,3- Attn: MAMO TCV Advocates Rec: 6497/8 dt 22/09/2006 26/03/2008 Jersey 08543-4000, Wef: 10/08/2006 thiazole-5-carboxamide and salts U.S.A. thereof

P.O. Box 4000, Route 203 and Province Line Fused Heterocyclic Compounds Bristol-Myers Squibb Company Filing Date: 22/09/2006 Wef: 22/09/2005 Warrant signed on 3783 Road, Princeton, New Vide PT 3783 useful as Kinase Modulators Attn: MAMO TCV Advocates Rec: 6494/5 dt 22/09/2006 Wef: 21/09/2006 26/03/2008 Jersey 08543-4000, U.S.A.

Carbosyamine Compounds and Novartis AG Lichtstrasse 35, 4056 Filing Date: 26/09/2006 Wef: 27/09/2005 Warrant signed on 3784 Vide PT 3784 Methods of Use thereof Attn: SS & Co. Basel, Switzerland Rec: 6586/7 dt 26/09/2006 Wef: 28/12/2005 09/04/2008

Novartis AG Lichtstrasse 35, 4056 Filing Date: 26/09/2006 Warrant signed on 3785 New Formulation Wef: 29/09/2005 Vide PT 3785 Attn: SS & Co. Basel, Switzerland Rec: 6582/3 dt 26/09/2006 09/04/2008

Filing Date: 26/09/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3786 Organic Compounds Rec: 6579/80 dt Wef: 28/09/2005 Vide PT 3786 Attn: SS & Co. Basel, Switzerland 07/04/2008 26/09/2006

Novartis AG Lichtstrasse 35, 4056 Filing Date: 26/09/2006 Warrant signed on 3787 Organic Compounds Wef: 30/09/2005 Vide PT 3787 Attn: SS & Co. Basel, Switzerland Rec: 6576/7 dt 26/09/2006 10/04/2008 Novartis AG Lichtstrasse 35, 4056 Filing Date: 26/09/2006 Warrant signed on 3788 Organic Compounds Wef: 30/09/2005 Vide PT 3788 Attn: SS & Co. Basel, Switzerland Rec: 6573/4 dt 26/09/2006 09/04/2008

New Process for the Synthesis of 12 Place de la Defense, Ivabradine and addition salts Les Laboratoires Servier Filing Date: 26/09/2006 Warrant signed on 3790 F-92415 Courbevoie Wef: N/A Vide PT 3790 thereof with a pharmaceutically Attn: SS & Co. Rec: 6567/8 dt 26/09/2006 22/10/2008 Cedex, France acceptable acid

Treatment of Inflammation and Shannon Airport House, Vasogen Ireland Limited Filing Date: 26/09/2006 Warrant signed on 3791 Vascular Abnormalities of the Shannon, County Clare, Wef: 26/09/2005 Vide PT 3791 Attn: B & M Patentburea Rec: 6636/7 dt 28/09/2006 16/11/2007 Eye Ireland

Crystalline Forms of [(1R), 2S]-2- P.O. Box 4000, Route Aminopropionic Acid 2-[4-(4- 203 and Province Line Fluoro-2-methyl-1H-Indol-5- Bristol-Myers Squibb Company Filing Date: 27/09/2006 Warrant signed on 3792 Road, Princeton, New Wef: 27/09/2005 Vide PT 3792 yloxy)-5-methylpyrrolo[2,1- Attn: MAMO TCV Advocates Rec: 6623/4 dt 27/09/2006 16/11/2007 Jersey 08543-4000, f][1,2,4]triazin-6-yloxy]-1- U.S.A. methylethyl ester

2-Amino-7,8-dihydro-6h- Novartis AG Lichtstrasse 35, 4056 Filing Date: 27/09/2006 Wef: 30/09/2005 Warrant signed on 3793 Vide PT 3793 pyrido[4,3-d]pyrimidin-5-ones Attn: CC Advocates Basel, Switzerland Rec: 6633/4 dt 28/09/2006 Wef: 09/08/2006 16/11/2007

P.O. Box 4000, Route 203 and Province Line Bristol-Myers Squibb Company Filing Date: 29/09/2006 Warrant signed on 3794 Met Kinase Inhibitors Road, Princeton, New Wef: 30/09/2005 Vide PT 3794 Attn: MAMO TCV Advocates Rec: 6688/9 dt 28/09/2006 16/11/2007 Jersey 08543-4000, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 29/09/2006 Warrant signed on 3795 Chemical Compounds Wef: 03/10/2005 Vide PT 3795 Attn: SS & Co. Sweden Rec: 6685/6 dt 29/09/2006 23/11/2007

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 29/09/2006 Warrant signed on 3796 New Compounds Wef: 03/10/2005 Vide PT 3796 Attn: SS & Co. Sweden Rec: 6682/3 dt 29/09/2006 23/11/2007

Currabinny, Carrigaline, SmithKline Beecham (Cork) Co. Cork, Republic of Limited & Neurocrine Ireland & 10555 Filing Date: 29/09/2006 Wef: 30/09/2005 Warrant signed on 3797 Chemical Compound Vide PT 3797 Biosciences Inc. Science Center Drive, Rec: 6680/1 dt 29/09/2006 Wef: 19/10/2005 14/11/2007 Attn: SS & Co. San Diego, CA 92121, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 29/09/2006 Warrant signed on 3798 New Compounds Wef: 03/10/2005 Vide PT 3798 Attn: SS & Co. Sweden Rec: 6677/8 dt 29/09/2006 23/11/2007 AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 29/09/2006 Warrant signed on 3799 New Compounds Wef: 03/10/2005 Vide PT 3799 Attn: SS & Co. Sweden Rec: 6673/4 dt 29/09/2006 23/11/2007

Glaxo Wellcome House, Compounds which have activity Glaxo Group Limited Berkeley Avenue, Filing Date: 29/09/2006 Wef: 30/09/2005 Warrant signed on 3800 at M, receptor and their uses in Vide PT 3800 Attn: SS & Co. Greenford, Middlesex Rec: 6670/1 dt 29/09/2006 Wef: 13/02/2006 14/11/2007 medicine UB6 0NN, Great Britain

Glaxo Wellcome House, Compounds which have activity Glaxo Group Limited Berkeley Avenue, Filing Date: 29/09/2006 Wef: 30/09/2005 Warrant signed on 3801 at M, receptor and their uses in Vide PT 3801 Attn: SS & Co. Greenford, Middlesex Rec: 6667/8 dt 29/09/2006 Wef: 01/02/2006 14/11/2007 medicine UB6 0NN, Great Britain

One Franklin Plaza, SmithKline Beecham P.O. Box 7929, Filing Date: 29/09/2006 Warrant signed on 3802 Pharmaceutical Compositions Corporation Wef: 30/09/2005 Vide PT 3802 Philadelphia, PA 19101, Rec: 6664/5 dt 29/09/2006 14/11/2007 Attn: SS & Co. U.S.A.

Use of at least one compound of the family of the avermectins or Zugerstrasse 8, CH- Galderma S.A. Filing Date: 02/10/2006 Wef: 30/09/2005 Warrant signed on 3803 of the family of the milbemycins 6330 Cham, Vide PT 3803 Attn: SS & Co. Rec: 6712/3 dt 02/10/2006 Wef: 05/07/2006 14/11/2007 in the treatment of ophthalmic Switzerland pathologies

126 Lincoln Avenue, Anti-Hypercholesterolemic Merck & Co. Inc. Filing Date: 02/10/2006 Warrant signed on 3805 Rahway, NJ 07065, Wef: 05/10/2005 Vide PT 3805 Compounds Attn: Chetcuti Cauchi Advocates Rec: 6721/2 dt 02/10/2006 23/11/2007 U.S.A.

Wef: 06/10/2005 AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 03/10/2006 Warrant signed on 3806 Novel Compounds Wef: 09/12/2005 Vide PT 3806 Attn: Salomone Sansone & Co. Sweden Rec: 6756/7 dt 03/10/2006 23/11/2007 Wef: 11/02/2006

Filing Date: 03/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3807 Therapeutic Agents Rec: 6759/60 dt Wef: 06/10/2005 Vide PT 3807 Attn: Salomone Sansone & Co. Sweden 23/11/2007 03/10/2006

Pharmaceutically Active Wef: 06/10/2005 Novartis AG Lichtstrasse 35, 4056 Filing Date: 03/10/2006 Warrant signed on 3808 Tetrahydro-pyrrolizinone Wef: 06/10/2005 Vide PT 3808 Attn: Salomone Sansone & Co. Basel, Switzerland Rec: 6762/3 dt 03/10/2006 23/11/2007 Compounds Wef: 06/10/2005

Wef: 07/10/2005 Eastern Point Road, Wef: 26/10/2005 Inhibitors of the HIV Integrase Pfizer Products Inc. Filing Date: 03/10/2006 Warrant signed on 3809 Groton, Connnecticut Wef: 24/01/2006 Vide PT 3809 Enzyme Attn: Salomone Sansone & Co. Rec: 6765/6 dt 03/10/2006 23/11/2007 06340, U.S.A. Wef: 30/08/2006 Wef: 20/09/2006 Separation of Fulvestrant Sicor Inc. 19 Hughes, Irvine, Filing Date: 05/10/2006 Warrant signed on 3810 Wef: 05/10/2005 Vide PT 3810 Isomers Attn: Chetcuti Cauchi Advocates California 92618, U.S.A. Rec: 6828/9 dt 06/10/2006 23/11/2007

Wef: 10/10/2005 Wef: 11/11/2005 Novartis AG Lichtstrasse 35, 4056 Filing Date: 06/10/2006 Warrant signed on 3811 Novel Compounds Wef: 27/02/2006 Vide PT 3811 Attn: Salomone Sansone & Co. Basel, Switzerland Rec: 6854/5 dt 06/10/2006 23/11/2007 Wef: 09/05/2006 Wef: 20/09/2006

Ronda del General Laboratorios Almirall S.A. Filing Date: 06/10/2006 Warrant signed on 3812 New Imidazopyridine Derivatives Mitre 151, 08022 Wef: 06/10/2005 Vide PT 3812 Attn: Salomone Sansone & Co. Rec: 6848/9 dt 06/10/2006 23/11/2007 Barcelona, Spain

Compositions and Processes Fructuós Gelabert, 6-8, Wef: 06/10/2005 Medichem S.A. Filing Date: 06/10/2006 Warrant signed on 3813 Useful for Preparing Tegaserod 08970 Sant Joan Despí, Wef: 12/10/2005 Vide PT 3813 Attn: Salomone Sansone & Co. Rec: 6843/4 dt 06/10/2006 23/11/2007 Maleate Barcelona, Spain Wef: 30/05/2006

Acyl Indoles, Compositions 126 East Lincoln Merck & Co. Inc. Filing Date: 09/10/2006 Warrant signed on 3814 containing Such compounds and Avenue, Rahway, NJ Wef: 13/10/2005 Vide PT 3814 Attn: Chetcuti Cauchi Advocates Rec: 6926/7 dt 10/10/2006 23/11/2007 methods of use 07065, U.S.A.

δ-crystalline form of ivabradine 12, Place de la Filing Date: 10/10/2006 hydrochloride, a process for its Les Laboratoires Servier Defense, F-92415 Warrant signed on 3815 Rec: 6919/20 dt Wef: 11/10/2005 Vide PT 3815 preparation and pharmaceutical Attn: Salomone Sansone & Co. Courbevoie Cedex, 23/11/2007 10/10/2006 compositions containing it France

δd-crystalline form of ivabradine 12, Place de la hydrochloride, a process for its Les Laboratoires Servier Defense, F-92415 Filing Date: 10/10/2006 Warrant signed on 3816 Wef: 11/10/2005 Vide PT 3816 preparation and pharmaceutical Attn: Salomone Sansone & Co. Courbevoie Cedex, Rec: 6921/2 dt 10/10/2006 23/11/2007 compositions containing it France

Glaxo Wellcome House, Wef: 10/10/2005 Glaxo Group Limited Berkeley Avenue, Filing Date: 10/10/2006 Wef: 11/11/2005 Warrant signed on 3817 Novel Compounds Vide PT 3817 Attn: Salomone Sansone & Co. Greenford, Middlesex Rec: 6923/4 dt 10/10/2006 Wef: 27/02/2006 23/11/2007 UB6 0NN, Great Britain Wef: 18/09/2006

Process for producing a single- phase pharmaceutical product Schering AG Müllerstraße 178, Berlin Filing Date: 10/10/2006 Wef: 13/10/2005 Warrant signed on 3818 Vide PT 3818 for oral therapy of dysfunctional Attn: MAMO TCV Advocates 13353, Germany Rec: 6913/4 dt 10/10/2006 Wef: 14/11/2005 23/11/2007 uterine bleeding Use of oestradiol valerate in combination with dienogest for the oral treatment of Schering AG Müllerstraße 178, Berlin Filing Date: 10/10/2006 Warrant signed on 3819 Wef: 13/10/2005 Vide PT 3819 dysfunctional uterine bleeding in Attn: MAMO TCV Advocates 13353, Germany Rec: 6915/6 dt 10/10/2006 23/11/2007 conjunnction with oral contraception

Use of methylene-4-azasteroids Schering AG Müllerstraße 178, Berlin Filing Date: 10/10/2006 3820 Wef: 14/10/2005 WITHDRAWN Vide PT 3820 as medicaments Attn: MAMO TCV Advocates 13353, Germany Rec: 6917/8 dt 10/10/2006 MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Glaxo Wellcome House, Filing Date: 11/102006 Wef: 13/10/2005 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3821 Novel Compounds Rec: 6970/1 dt Wef: 06/07/2006 Vide PT 3821 Attn: SS & Co. Greenford, Middlesex 23/11/2007 12/10/2006 Wef: 15/09/2006 UB6 0NN, Great Britain

Crystalline forms of Filing Date: 12/102006 Wef: 12/10/2005 Sicor Inc. 19 Hughes, Irvine, Warrant signed on 3822 docetaxel and processes for Rec: 7013/4 dt Wef: 17/10/2005 Vide PT 3822 Attn: CC Advocates California 92618, U.S.A. 23/11/2007 their preparation 13/10/2006 Wef: 16/11/2005

Filing Date: 16/102006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3823 Organic Compounds Rec: 7050/1 dt Wef: 17/10/2005 Vide PT 3823 Attn: SS & Co. Basel, Switzerland 23/11/2007 17/10/2006

Pyrazole derivatives, 126 East Lincoln Filing Date: 16/102006 compositions containing Merck & Co. Inc. Warrant signed on 3824 Avenue, Rahway NJ Rec: 7045/6 dt Wef: 19/10/2005 Vide PT 3824 such compounds and Attn: CC Advocates 23/11/2007 07065, U.S.A. 17/10/2006 methods of use

Filing Date: 17/102006 Novartis AG Lichtstrasse 35, 4056 Wef: 21/10/2005 Warrant signed on 3825 Organic Molecules Rec: 7085/6 dt Vide PT 3825 Attn: SS & Co. Basel, Switzerland Wef: 22/08/2006 03/01/2008 17/10/2006

Filing Date: 17/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3826 Benzamide Compounds Rec: 7056/7 dt Wef: 19/10/2005 Vide PT 3826 Attn: SS & Co. Sweden 03/01/2008 17/10/2006

327 Cambridge Science KuDOS Pharmaceuticals Filing Date: 17/10/2006 Wef: 19/10/2005 Park, Milton Road, Warrant signed on 3827 Phthalazinone Derivatives Limited Rec: 7059/60 dt Wef: 20/10/2005 Vide PT 3827 Cambridge CB4 0WG, 03/01/2008 Attn: SS & Co. 17/10/2006 Wef: 17/08/2006 U.K.

AstraZeneca AB & Bayer SE-151 85 Sodertalje, Filing Date: 17/10/2006 Schering Pharma Sweden & Müllerstrasse Wef: 20/10/2005 Warrant signed on 3828 Chemical Compounds Rec: 7062/3 dt Vide PT 3828 Aktiengesellschaft 178, 13342 Berlin, Wef: 03/04/2006 03/01/2008 17/10/2006 Attn: SS & Co. Germany

Berzelius väg 3, plan 5, Filing Date: 17/10/2006 Pyrazoles useful in the Biolipox AB Warrant signed on 3829 SE-171 65, Solna, Rec: 7065/6 dt Wef: 20/10/2005 Vide PT 3829 treatment of inflammation Attn: SS & Co. 03/01/2008 Sweden 17/10/2006

One Amgen Center Methods of Decreasing Filing Date: 18/10/2006 Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3830 Vascular Calcification using Rec: 7120/1 dt Wef: 21/10/2005 Vide PT 3830 Attn: CC Advocates California 91320-1799, 11/12/2007 IL-1 Inhibitors 23/10/2006 U.S.A. Enhanced Efficacy 1900 Charleston Road, Filing Date: 18/10/2006 Alza Corporation Wef: 19/10/2005 Warrant signed on 3831 Benzisoxazole Derivatve Mountain View, CA Rec: P585651 dt Vide PT 3831 Attn: EMD Advocates Wef: 27/10/2005 11/12/2007 Dosage Forms and Methods 94043, U.S.A. 18/10/2006

P.O. Box 4000, Route Use of Dasatinib For the 206 and Province Line Filing Date: 20/10/2006 Bristol-Myers Squibb Company Warrant signed on 3832 Treatment of Bone Road, Princeton, New Rec: 7127/8 dt Wef: 20/10/2005 Vide PT 3832 Attn: MAMO TCV Advocates 11/12/2007 Metastasis Jersey 08543-4000, 23/10/2006 U.S.A.

P.O. Box 4000, Route 206 and Province Line Filing Date: 20/10/2006 Bristol-Myers Squibb Company Warrant signed on 3833 LXR Modulators Road, Princeton, New Rec: 7124/6 dt Wef: 21/10/2005 Vide PT 3833 Attn: MAMO TCV Advocates 11/12/2007 Jersey 08543-4000, 23/10/2006 U.S.A.

Glaxo Wellcome House, Filing Date: 20/10/2006 Glaxo Group Limited Berkeley Avenue, Wef: 21/10/2005 Warrant signed on 3834 Compounds Rec: 7129/30 dt Vide PT 3834 Attn: SS & Co. Greenford, Middlesex Wef: 22/09/2006 11/12/2007 23/10/2006 UB6 0NN, Great Britain

New Aminoesterified Camptothecin Analogue Compounds having a six- 12, Place De La membered hydrocarbon E Les Laboratoires Servier Defense, F-92415 Filing Date: 20/10/2006 Warrant signed on 3835 ring, a process for their Wef: 24/10/2005 Vide PT 3835 Attn: SS & Co. Courbevoie Cedex, Rec: 7176 dt 23/10/2006 11/12/2007 preparation and France pharmaceutical compositions containing them

Glaxo Wellcome House, Filing Date: 20/10/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3836 Novel Compounds Rec: 7179/80 dt Wef: 21/10/2005 Vide PT 3836 Attn: SS & Co. Greenford, Middlesex 03/01/2008 23/10/2006 UB6 0NN, Great Britain

One Amgen Center CGRP Peptide Antagonists Amgen Inc. Drive, Thousand Oaks, Filing Date: 20/10/2006 Wef: 21/10/2005 Warrant signed on 3837 Vide PT 3837 and Conjugates Attn: CC Advocates California 91320-1799, Rec: 7132 dt 23/10/2006 Wef: 19/10/2006 23/01/2008 U.S.A.

One Amgen Center Filing Date: 20/10/2006 Methods for Generating Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3838 Rec: 7135/6 dt Wef: 21/10/2005 Vide PT 3838 Monovalent IgG Attn: CC Advocates California 91320-1799, 03/01/2008 23/10/2006 U.S.A. Chromenones and Their use Merz Pharma GmbH & Co. 100 Eckenheimer Filing Date: 20/10/2006 as Modulators of Warrant signed on 3839 KGAA Landstrasse, D-60318 Rec: 7138/9 dt Wef: 21/10/2005 Vide PT 3839 Metabotropic Glutamate 03/01/2008 Attn: CC Advocates Frankfurt, Germany 23/10/2006 Receptors

4 Willsborough Cluster, Filing Date: 23/10/2006 Ramipril Composition with Selamine Ltd. Clonshaugh, Industrial Wef: 21/10/2005 Warrant signed on 3840 Rec: 7208/9 dt Vide PT 3840 Improved Stability Attn: SS & Co. Estate, Dublin 17, Wef: 28/10/2005 03/01/2008 24/10/2006 Ireland

One Amgen Center Filing Date: 23/10/2006 Compounds and Methods of Amgen Inc. Warrant signed on 3841 Drive, Thousand Oaks, Rec: 7222/3 dt Wef: 21/10/2005 Vide PT 3841 Use Attn: CC Advocates 03/01/2008 CA 91320-1799, U.S.A. 24/10/2006

Filing Date: 24/10/2006 Novel use of IL-1beta Novartis AG Lichtstrasse 35, 4056 Wef: 26/10/2005 Warrant signed on 3842 Rec: 7211/2 dt Vide PT 3842 Compounds Attn: SS & Co. Basel, Switzerland Wef: 02/12/2005 03/01/2008 24/10/2006

Filing Date: 24/10/2006 Modulators of Chemokine Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3843 Rec: 7213/4 dt Wef: 25/10/2005 Vide PT 3843 Receptor Activity Attn: SS & Co. Basel, Switzerland 02/01/2008 24/10/2006

One Franklin Plaza, SmithKline Beecham Filing Date: 24/10/2006 Substituted Thiazoles and P.O. Box 7929, Warrant signed on 3844 Corporation Rec: 7216/7 dt Wef: 26/10/2005 Vide PT 3844 Their Use Philadelphia, PA 19101, 02/01/2008 Attn: SS & Co. 24/10/2006 U.S.A.

Galderma Research & 2400 Route des Colles, Filing Date: 24/10/2006 PPAR-modulating Wef: 26/10/2005 Warrant signed on 3845 Development S.N.C. Les Templiers 06410 Rec: 7219/20 dt Vide PT 3845 biaromatic compounds Wef: 09/11/2005 06/12/2007 Attn: SS & Co. BIOT, France 24/10/2006

A 4-oxo-1-(3-substituted phenyl)-1, 4-dihydro-1, 8- 16711 Trans-Canada naphthyridine-3- Filing Date: 24/10/2006 Merck Frosst Canada Ltd. Highway, Kirkland, Warrant signed on 3846 carboxamide Rec: 7275/7 dt Wef: 27/10/2005 Vide PT 3846 Attn: CC Advocates Qubec, Canada H9H 06/12/2007 phosphodiesterase-4 26/10/2006 3L1 inhibitor and a method of preparing same

Filing Date: 25/10/2006 Fast Dissociating Dopamine Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3848 Rec: 7263/4 dt Wef: 26/10/2005 Vide PT 3848 2 Receptor Antagonists Attn: EMD Advocates 2340 Beerse, Belgium 06/12/2007 26/10/2006 P.O. Box 4000, Route Non-Basic Melanin 206 and Province Line Filing Date: 26/10/2006 Bristol-Myers Squibb Company Wef: 26/10/2005 Warrant signed on 3849 Concentrating Hormone Road, Princeton, New Rec: 7266/7 dt Vide PT 3849 Attn: MAMO TCV Advocates Wef: 25/10/2006 06/12/2007 Receptor-1 Antagonists Jersey 08543-4000, 26/10/2006 U.S.A.

Glaxo Wellcome House, Filing Date: 27/10/2006 Glaxo Group Limited Berkeley Avenue, Wef: 28/10/2005 Warrant signed on 3850 Novel Compound Rec: 7290/1 dt Vide PT 3850 Attn: SS & Co. Greenford, Middlesex Wef: 09/10/2006 06/12/2007 27/10/2006 UB6 0NN, Great Britain

Eastern Point Road, Filing Date: 27/10/2006 Histamine-3 receptor Pfizer Products Inc. Warrant signed on 3851 Groton, Connecticut Rec: 7296/7 dt Wef: 27/10/2005 Vide PT 3851 antagonists Attn: SS & Co. 06/12/2007 06340, U.S.A. 27/10/2006

Filing Date: 27/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Wef: 28/10/2005 Warrant signed on 3852 Chemical Compounds Rec: 7299/300 dt Vide PT 3852 Attn: SS & Co. Sweden Wef: 24/05/2006 06/12/2007 27/10/2006

Berzelius väg 3, plan 5 Filing Date: 27/10/2006 Pyrazoles useful in the Biolipox AB Warrant signed on 3853 SE-171 65, Solna, Rec: 7302/3 dt Wef: 31/10/2005 Vide PT 3853 treatment of inflammation Attn: SS & Co. 06/12/2007 Sweden 27/10/2006

Heterocyclic substituted Wef: 31/10/2005 6-10, Koishikawa 4- Filing Date: 27/10/2006 pyridine derivatives and Eisai R&D Management Co. Ltd. Wef: 27/12/2005 Warrant signed on 3854 chome, Bunkyo-ku, Rec: 7293/4 dt Vide PT 3854 antifungal agent containing Attn: GS Services Limited Wef: 31/10/2005 06/12/2007 Tokyo 112-8088, Japan 27/10/2006 same Wef: 27/12/2005

Process for the preparation Fructuós Gelabert, 6-8, Filing Date: 27/10/2006 Medichem S.A. Warrant signed on 3855 of tamsulosin and related 08970 Sant Joan Despí, Rec: 7376/7 dt Wef: 28/10/2005 Vide PT 3855 Attn: SS & Co. 06/12/2007 compounds Barcelona, Spain 30/10/2006

P.O. Box 4000, Route Pyrrolidinyl Beta-amino 206 and Province Line Filing Date: 31/10/2006 Amide-based inhibitors of Bristol-Myers Squibb Company Warrant signed on 3856 Road, Princeton, New Rec: 7401/2 dt Wef: 31/10/2005 Vide PT 3856 dipeptidyl peptidase IV and Attn: MAMO TCV Advocates 06/12/2007 Jersey 08543-4000, 31/10/2006 methods U.S.A.

P.O. Box 4000, Route 206 and Province Line Filing Date: 31/10/2006 Protective Outer Enclosure Bristol-Myers Squibb Company Warrant signed on 3857 Road, Princeton, New Rec: 7404/5 dt Wef: 03/11/2005 Vide PT 3857 for Pharmaceutical Vial Attn: MAMO TCV Advocates 10/01/2008 Jersey 08543-4000, 31/10/2006 U.S.A. One Amgen Center Filing Date: 31/10/2006 Novel Activin Receptor and Amgen Inc. Drive, Thousand Oaks, Warrant signed on 3858 Rec: 7407/8 dt Wef: 01/11/2005 Vide PT 3858 Uses thereof Attn: MAMO TCV Advocates California 91320-1799, 10/01/2008 31/10/2006 U.S.A.

Filing Date: 31/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3859 Novel Compounds Rec: 7432/3 dt Wef: 02/11/2005 Vide PT 3859 Attn: Salomone Sansone & Co. Sweden 10/01/2008 31/10/2006

Solid Pharmaceutical Eastern Point Road, Filing Date: 31/10/2006 Pfizer Products Inc. Warrant signed on 3860 Compositions containing Groton, Connecticut Rec: 7435/6 dt Wef: 02/11/2005 Vide PT 3860 Attn: Salomone Sansone & Co. 10/01/2008 pregabalin 06340, U.S.A. 31/10/2006

Ramsgate Road, Filing Date: 31/10/2006 Pfizer Limited Warrant signed on 3861 Pyrazine Derivatives Sandwich, Kent CT13 Rec: 7438/9 dt Wef: 04/11/2005 Vide PT 3861 Attn: SS & Co. 10/01/2008 9NJ, England 31/10/2006

Filing Date: 31/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3862 Chroman Compounds Rec: 7441/2 dt Wef: 04/11/2005 Vide PT 3862 Attn: SS & Co. Sweden 10/01/2008 31/10/2006

Filing Date: 31/10/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3863 Chroman Compounds Rec: 7524/5 dt Wef: 04/11/2005 Vide PT 3863 Attn: SS & Co. Sweden 10/01/2008 31/10/2006

Urea Derivatives, processes for their preparation, their 102 route de Noisy, F- Filing Date: 31/10/2006 use as medicaments, and Galapagos SAS Warrant signed on 3864 92230 Romainville, Rec: 7426/7 dt Wef: 25/11/2005 Vide PT 3864 pharmaceutical Attn: SS & Co. 10/01/2008 France 31/10/2006 compositions containing them

126 East Lincoln Filing Date: 31/10/2006 Merck & Co. Inc. Warrant signed on 3865 HIV Integrase Inhibitors Avenue, Rahway, NJ Rec: 7449/50 dt Wef: N/A Vide PT 3865 Attn: CC Advocates 23/10/2008 07065, U.S.A. 31/10/2006

Centre Industriel, 1267 Filing Date: 31/10/2006 Novel CXC-Chemokine Laboratoires Serono SA Wef: 31/10/2005 Warrant signed on 3866 Coinsins, Vaud, Rec: 7466/7 dt Vide PT 3866 Antagonists Attn: CC Advocates Wef: 04/11/2005 06/12/2007 Switzerland 31/10/2006 A process for the Filing Date: 01/11/2006 Dipharma S.p.A. Via XXIV Maggio 40, Warrant signed on 3867 preparation of angiotensin II Rec: 7456/7 dt Wef: 20/10/2005 Vide PT 3867 Attn: Dr. Alex Perici Calascione Mereto Di Tomba, Italy 06/12/2007 antagonistic compounds 01/11/2006

126 East Lincoln Filing Date: 02/11/2006 Merck & Co. Inc. Wef: 07/11/2005 Warrant signed on 3868 Inhibitors of AKT Activity Avenue, Rahway, NJ Rec: 7522/3 dt Vide PT 3868 Attn: CC Advocates Wef: 07/06/2006 10/01/2008 07065, U.S.A. 03/11/2006

Process for the Manufacture 11388 Sorrento Valley Filing Date: 03/11/2006 of Ppetide Facilitators of Avanir Pharmaceuticals Road, Suite 200, San Warrant signed on 3869 Rec: 7573/4 dt Wef: 04/11/2005 Vide PT 3869 Reverse Cholesterol Attn: SS & Co. Diego, CA 92121, 10/01/2008 07/11/2006 Transport U.S.A.

130 Waverly Street, Vertex Pharmaceuticals Filing Date: 03/11/2006 Aminopyrimidines Useful as Cambridge, Wef: 03/11/2005 Warrant signed on 3870 Incorporated Rec: 7576/7 dt Vide PT 3870 Kinase Inhibitors Massachusetts 02139, Wef: 04/11/2005 10/01/2008 Attn: SS & Co. 07/11/2006 U.S.A.

130 Waverly Street, Vertex Pharmaceuticals Filing Date: 03/11/2006 Aminopyrimidines Useful as Cambridge, Wef: 03/11/2005 Warrant signed on 3871 Incorporated Rec: 7579/80 dt Vide PT 3871 Kinase Inhibitors Massachusetts 02139, Wef: 04/11/2005 10/01/2008 Attn: SS & Co. 07/11/2006 U.S.A.

130 Waverly Street, Vertex Pharmaceuticals Filing Date: 03/11/2006 Aminopyrimidines Useful as Cambridge, Wef: 03/11/2005 Warrant signed on 3872 Incorporated Rec: 7582/3 dt Vide PT 3872 Kinase Inhibitors Massachusetts 02139, Wef: 04/11/2005 10/01/2008 Attn: SS & Co. 07/11/2006 U.S.A.

[4-(6-halo-7-substituted-2,4- dioxo-1,4-dihydro-2H- 270 E. Grand Avenue, Filing Date: 03/11/2006 quinazolin-3-yl)-phenyl]-5- Portola Pharmaceuticals Inc. Suite 22, South San Warrant signed on 3873 Rec: 7534/5 dt Wef: 03/11/2005 Vide PT 3873 chloro-thiophen-2-yl- Attn: CC Advocates Francisco, CA 94080, 10/01/2008 07/11/2006 sulfonylureas and forms and U.S.A. methods related thereto

Substituted- 270 E. Grand Avenue, (quinazolinyl)phenyl Filing Date: 03/11/2006 Portola Pharmaceuticals Inc. Suite 22, South San Warrant signed on 3874 thiophenyl-sulfonylureas, Rec: 7531/2 dt Wef: 03/11/2005 Vide PT 3874 Attn: CC Advocates Francisco, CA 94080, 10/01/2008 methods for making and 07/11/2006 U.S.A. intermediates thereof Glaxo Wellcome House, Berkeley Avenue, Glaxo Group Limited & Greenford, Middlesex Filing Date: 07/11/2006 GlaxoSmithKline istrazivacki Wef: 09/11/2005 Warrant signed on 3875 Macrolones UB6 0NN, Great Britain Rec: 7556/7 dt Vide PT 3875 centar Zagreb Wef: 11/05/2006 11/01/2008 & Prilaz boruna 07/11/2006 Attn: SS & Co. Filipovica 29, 10000 Zagreb, Croatia

Glaxo Wellcome House, Filing Date: 07/11/2006 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3876 Macrolones Rec: 7559/60 dt Wef: 09/11/2005 Vide PT 3876 Attn: SS & Co. Greenford, Middlesex 10/01/2008 07/11/2006 UB6 0NN, Great Britain

Ramsgate Road, Filing Date: 07/11/2006 Compounds Useful in Pfizer Limited Warrant signed on 3877 Sandwich, Kent CT13 Rec: 7561/2 dt Wef: 08/11/2005 Vide PT 3877 Therapy Attn: SS & Co. 10/01/2008 9NJ, England 07/11/2006

1-(1-(2-ethoxyethyl)-3-ethyl-7- (4-methylpyridin-2-ylamino)- Eastern Point Road, Filing Date: 07/11/2006 Pfizer Products Inc. Warrant signed on 3878 1H-pyrazolo[4,3-d]pyrimidin- Groton, Connecticut Rec: 7564/5 dt Wef: 10/11/2005 Vide PT 3878 Attn: SS & Co. 10/01/2008 5-yl)piperidine-4-carboxylic 06340, U.S.A. 07/11/2006 acid and salts thereof

One Franklin Plaza, SmithKline Beecham Filing Date: 07/11/2006 P.O. Box 7929, Warrant signed on 3879 Novel Chemical Compounds Corporation Rec: 7567/8 dt Wef: 08/11/2005 Vide PT 3879 Philadelphia, PA 19101, 10/01/2008 Attn: SS & Co. 07/11/2006 U.S.A.

Wef: 09/11/2005 Filing Date: 07/11/2006 Novartis AG Lichtstrasse 35, 4056 Wef: 10/11/2005 Warrant signed on 3880 Organic Compounds Rec: 7570/1 dt Vide PT 3880 Attn: SS & Co. Basel, Switzerland Wef: 04/04/2006 10/01/2008 07/11/2006 Wef: 11/08/2006

Novel Pharmaceutical Salts Millennium Pharmaceuticals 40 Landsdowne Street, Filing Date: 08/11/2006 Warrant signed on 3881 and Polymorphs of a Factor Inc. Cambridge, MA 02139, Rec: 7592/3 dt Wef: 08/11/2005 Vide PT 3881 10/01/2008 Xa Inhibitor Attn: SS & Co. U.S.A. 08/11/2006

Oral Formulations Combino Pharm S.L. Fructuós Gelabert, 6-8, Filing Date: 10/11/2006 Warrant signed on 3882 Comprising 3'- Attn: Bezzina & Mifsud 08970 Saint Joan Rec: 7636/7 dt Wef: 10/11/2005 Vide PT 3882 10/01/2008 Azidonucleosides Patentbureau Despí, Barcelona, Spain 10/11/2006 One Amgen Center Amgen Inc. Filing Date: 10/11/2006 Rankl Antibody-PTH/PTHrP Drive, Mail Stop 27-4-A, Warrant signed on 3883 Attn: Bezzina & Mifsud Rec: 7639/40 dt Wef: 14/11/2005 Vide PT 3883 Chimeric Molecules Thousand Oaks, 10/01/2008 Patentbureau 10/11/2006 California 91320, U.S.A.

One Franklin Plaza, SmithKline Beecham Filing Date: 10/11/2006 Wef: 10/11/2005 P.O. Box 7929, Warrant signed on 3884 Inhibitors of AKT Activity Corporation Rec: 7650/1 dt Wef: 10/02/2006 Vide PT 3884 Philadelphia, PA 19101, 10/01/2008 Attn: SS & Co. 10/11/2006 Wef: 26/09/2006 U.S.A.

Anti-proliferative combination therapy using Fraunhoferstr. 20, Filing Date: 10/11/2006 certain platinum-based GPC Biotech AG Warrant signed on 3885 Martinsfried 82152, Rec: 7659/61 dt Wef: 11/11/2005 Vide PT 3885 chemotherapeutic agents Attn: MAMO TCV Advocates 10/01/2008 Germany 13/11/2006 and EGFR inhibitors of pyrimidine analogues

Vitae Pharmaceuticals Inc. 502 West Office Center Filing Date: 14/11/2006 Wef: 14/11/2005 Warrant signed on 3886 Aspartic Protease Inhibitors Attn: Bezzina & Mifsud Drive, Fort Washington, Rec: 7692/3 dt Wef: 18/09/2006 Vide PT 3886 11/01/2008 Patentbureau PA 19034, U.S.A. 14/11/2006 Wef: 18/09/2006

436 Cambridge Science Astex Therapeutics Limited & Park, Milton Road, Filing Date: 14/11/2006 Compounds and uses Warrant signed on 3887 AstraZeneca AB Cambridge, CB4 0QA, Rec: 7689/90 dt Wef: 15/11/2005 Vide PT 3887 thereof 11/01/2008 Attn: SS & Co. U.K. & SE-151 85 14/11/2006 Sodertalje, Sweden

Filing Date: 14/11/2006 Pharmaceutical AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3888 Rec: 7686/7 dt Wef: 18/11/2005 Vide PT 3888 Compositions Attn: SS & Co. Sweden 11/01/2008 14/11/2006

Glaxo Wellcome House, Filing Date: 14/11/2006 Novel Process and Glaxo Group Limited Berkeley Avenue, Warrant signed on 3889 Rec: 7683/4 dt Wef: 15/11/2005 Vide PT 3889 Formulations Attn: SS & Co. Greenford, Middlesex 11/01/2008 14/11/2006 UB6 0NN, Great Britain

280 East Grand Filing Date: 14/11/2006 Certain Chemical Entities, Cytokinetics Inc. Avenue, South San Warrant signed on 3890 Rec: 7680/1 dt Wef: 15/11/2005 Vide PT 3890 Compositions, and Methods Attn: SS & Co. Francisco, CA 94080, 11/01/2008 14/11/2006 U.S.A. Improved Synthesis and Preparations of Fructuós Gelabert, 6-8, Filing Date: 14/11/2006 Intermediates and New Medichem S.A. Warrant signed on 3891 08970 Sant Joan Despí, Rec: 7696/7 dt Wef: 14/11/2005 Vide PT 3891 Polymorphs thereof useful Attn: SS & Co. 11/01/2008 Barcelona, Spain 14/11/2006 for the preparation of donepezil hydrochloride

Glaxo Wellcome House, Filing Date: 16/11/2006 New Pleuromutilin Glaxo Group Limited Berkeley Avenue, Warrant signed on 3892 Rec: 7748/9 dt Wef: 18/11/2005 Vide PT 3892 Derivatives and its use Attn: SS & Co. Greenford, Middlesex 11/01/2008 16/11/2006 UB6 0NN, Great Britain

41 Pinelawn Road, Filing Date: 16/11/2006 Fused Bicyclic mTOR OSI Pharmaceuticals Inc. Wef: 17/11/2005 Warrant signed on 3893 Melville, NY 11747, Rec: 7751/2 dt Vide PT 3893 Inhibitors Attn: SS & Co. Wef: 25/10/2006 11/01/2008 U.S.A. 16/11/2006

One Amgen Center Filing Date: 16/11/2006 Beta-Secretase Modulators Amgen Inc. Drive, Thousand Oaks, Wef: 21/11/2005 Warrant signed on 3894 Rec: 7745/6 dt Vide PT 3894 and Methods of Use Attn: CC Advocates California 91320-1799, Wef: 27/10/2006 11/01/2008 16/11/2006 U.S.A.

P.O. Box 4000, Route 206 and Province Line Filing Date: 17/11/2006 Bristol-Myers Squibb Company Wef: 17/11/2005 Warrant signed on 3895 HIV Integrase Inhibitors Road, Princeton, New Rec: 7774/5 dt Vide PT 3895 Attn: MAMO TCV Advocates Wef: 31/10/2006 11/01/2008 Jersey 08543-4000, 20/11/2006 U.S.A.

P.O. Box 4000, Route Filing date: 17/11/2006 206 and Province Line Pyrrolotriazine Kinase Bristol-Myers Squibb Company Rec 7780/1 of 20/11/2006 Warrant signed on 3896 Road, Princeton, New Wef: 18/11/05 Vide PT 3896 Inhibitors Attn: MAMO TCV Advocates Claims Fee: Lm60 11/01/2008 Jersey 08543-4000, Rec 7782 of 20/11/2006 U.S.A.

9-chloro-15- deoxyprostaglandin Filing Date: 17/11/2006 Schering AG Warrant signed on 3897 derivatives, process for their Berlin 13342, Germany Rec: 7778/9 dt Wef: 21/11/2005 Vide PT 3897 Attn: MAMO TCV Advocates 11/01/2008 preparation and their use as 20/11/2006 medicaments

Filing Date: 17/11/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3898 Organic Compounds Rec: 7783/4 dt Wef: 21/11/2005 Vide PT 3898 Attn: SS & Co. Basel, Switzerland 11/01/2008 20/11/2006 Filing Date: 17/11/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3899 Organic Compounds Rec: 7786/7 dt Wef: 21/11/2005 Vide PT 3899 Attn: SS & Co. Basel, Switzerland 11/01/2008 20/11/2006

6-9, Hiranomachi 2- chome, Chuo-ku, Mitsubishi Pharma Corporation Filing Date: 17/11/2006 Substituted Bicyclic Osaka-shi, Osaka 541- Warrant signed on 3900 & Sanofi-Aventis Rec: 7789/90 dt Wef: 21/11/2005 Vide PT 3900 Pyrimidone Derivatives 0046, Japan & 174, 11/01/2008 Attn: SS & Co. 20/11/2006 Avenue de France, FR- 75013 Paris, France

436 Cambridge Science Astex Therapeutics Ltd. & Park, Milton Road, Filing Date: 17/11/2006 Wef: 21/11/2005 Warrant signed on 3901 New Compounds AstraZeneca AB Cambridge CB4 0QA, Rec: 7792/3 dt Vide PT 3901 Wef: 22/06/2006 11/01/2008 Attn: SS & Co. U.K. & SE-151 85 20/11/2006 Sodertalje, Sweden

Glaxo Wellcome House, Filing Date: 17/11/2006 Pleuromutilin Derivatives Glaxo Group Limited Berkeley Avenue, Warrant signed on 3902 Rec: 7795/6 dt Wef: 18/11/2005 Vide PT 3902 and Their Use Attn: SS & Co. Greenford, Middlesex 11/01/2008 20/11/2006 UB6 0NN, Great Britain

126 East Lincoln Filing Date: 20/11/2006 Merck & Co. Inc. Warrant signed on 3903 Spirocyclic Compounds Avenue, Rahway, NJ Rec: 7784/5 dt Wef: 23/11/2005 Vide PT 3903 Attn: CC Advocates 11/01/2008 07065, U.S.A. 22/11/2006

6-10, Koishikawa 4- Filing Date: 21/11/2006 Morpholine Type Cinnamide Eisai R&D Management Co. Ltd. Wef: 24/11/2005 Warrant signed on 3904 chome, Bunkyo-ku, Rec: 7876/7 dt Vide PT 3904 Compound Attn: SS & Co. Wef: 28/07/2006 11/01/2008 Tokyo, Japan 21/11/2006

6-10, Koishikawa 4- Filing Date: 21/11/2006 Two Cyclic Cinnamide Eisai R&D Management Co. Ltd. Wef: 24/11/2005 Warrant signed on 3905 chome, Bunkyo-ku, Rec: 7873/4 dt Vide PT 3905 Comound Attn: SS & Co. Wef: 28/07/2006 11/01/2008 Tokyo, Japan 21/11/2006

901 Gateway Filing Date: 21/11/2006 Carbamate Compounds as Theravance Inc. Boulevard, South San Warrant signed on 3906 Rec: 7870/1 dt Wef: 22/11/2005 Vide PT 3906 5HT-4 Receptor Agonists Attn: SS & Co. Francisco, CA 94080, 11/01/2008 21/11/2006 U.S.A.

Filing Date: 21/11/2006 Pharmaceutical AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3907 Rec: 7867/8 dt Wef: 23/11/2005 Vide PT 3907 Compositions Attn: SS & Co. Sweden 11/01/2008 21/11/2006 Filing Date: 21/11/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3908 New Compounds Rec: 7864/5 dt Wef: 24/11/2005 Vide PT 3908 Attn: SS & Co. Sweden 11/01/2008 21/11/2006

Pyrido-, pyrazo- and Wef: 22/11/2005 KuDOS Pharmaceuticals Filing Date: 21/11/2006 pyrimido-pyramidine 15 Stanhope Gate, Wef: 25/11/2005 Warrant signed on 3909 Limited Rec: 7861/2 dt Vide PT 3909 derivatives and their use as London W1K 1NL, U.K. Wef: 23/08/2006 23/01/2008 Attn: SS & Co. 21/11/2006 mTOR Inhibitors Wef: 23/08/2006

Wef: 21/11/2005 2-1, Toranomon 2- Filing Date: 21/11/2006 Heterocyclic Compound and Japan Tobacco Inc. Wef: 05/12/2005 Warrant signed on 3910 chome, Minato-ku, Rec: 7858/9 dt Vide PT 3910 Pharmaceutical Use Thereof Attn: SS & Co. Wef: 29/03/2006 23/01/2008 Tokyo 105-8422, Japan 21/11/2006 Wef: 10/04/2006

One Amgen Center Drive, Thousand Oaks, Inhibitors of 11-beta- Filing Date: 21/11/2006 Amgen Inc & Biovitrum AB CA 91320-1799, U.S.A. Warrant signed on 3912 hydroxy steroid Rec: 7855/6 dt Wef: 22/11/2005 Vide PT 3912 Attn: SS & Co. & Lindhagensgatan 23/01/2008 dehydrogenase Type 1 21/11/2006 133, Stockholm, SE-112 76, Sweden

One Amgen Center Filing Date: 21/11/2006 Beta-Secretase Modulators Amgen Inc. Warrant signed on 3913 Drive, Thousand Oaks, Rec: 7879/80 dt Wef: 21/11/2005 Vide PT 3913 and Methods of Use Attn: SS & Co. 23/01/2008 CA 91320-1799, U.S.A. 22/11/2006

One Amgen Center Filing Date: 21/11/2006 Beta-Secretase Modulators Amgen Inc. Wef: 21/11/2005 Warrant signed on 3914 Drive, Thousand Oaks, Rec: 7866/7 dt Vide PT 3914 and Methods of Use Attn: SS & Co. Wef: 14/11/2006 23/01/2008 CA 91320-1799, U.S.A. 22/11/2006

One Franklin Plaza, SmithKline Beecham Filing Date: 22/11/2006 P.O. Box 7929, Wef: 22/11/2005 Warrant signed on 3915 Calcilytic Compounds Corporation Rec: 7892/3 dt Vide PT 3915 Philadelphia, PA 19101, Wef: 22/11/2005 23/01/2008 Attn: SS & Co. 22/11/2006 U.S.A.

P.O. Box 4000, Route 206 and Province Line Filing Date: 23/11/2006 Bristol-Myers Squibb Company Wef: 23/11/2005 Warrant signed on 3916 Heterocyclic CETP Inhibitors Road, Princeton, New Rec: 7914/5 dt Vide PT 3916 Attn: MAMO TCV Advocates Wef: 13/11/2006 23/01/2008 Jersey 08543-4000, 23/11/2006 U.S.A.

P.O. Box 4000, Route 206 and Province Line Filing Date: 23/11/2006 Bristol-Myers Squibb Company Wef: 23/11/2005 Warrant signed on 3917 Heterocyclic CETP Inhibitors Road, Princeton, New Rec: 7911/2 dt Vide PT 3917 Attn: MAMO TCV Advocates Wef: 16/11/2006 23/01/2008 Jersey 08543-4000, 23/11/2006 U.S.A. P.O. Box 4000, Route 206 and Province Line Filing Date: 23/11/2006 Bristol-Myers Squibb Company Wef: 23/11/2005 Warrant signed on Heterocyclic CETP Inhibitors Road, Princeton, New Rec: 7917/8 dt Vide PT 3918 Attn: MAMO TCV Advocates Wef: 15/11/2006 23/01/2008 Jersey 08543-4000, 23/11/2006 U.S.A.

126 East Lincoln Filing Date: 23/11/2006 Heterocycle-substituted 3- Merck & Co. Inc. Warrant signed on 3919 Avenue, Rahway, NJ Rec: 7984/5 dt Wef: 28/11/2005 Vide PT 3919 alkyl azetidine Derivatives Attn: CC Advocates 23/01/2008 07065, U.S.A. 27/11/2006

Eckenheimer Merz Pharma GmbH & Co. Filing Date: 23/11/2006 Meramexane Modified Landstrasse 100, 60318 Warrant signed on 3920 KGAA Rec: 7986/7 dt Wef: 30/11/2005 Vide PT 3920 Release Matrix Tablet Frankfurt am Main, 23/01/2008 Attn: CC Advocates 27/11/2006 Germany

Glaxo Wellcome House, Filing Date: 24/11/2006 Wef: 24/11/2005 Glaxo Group Limited Berkeley Avenue, Warrant signed on 3921 Chemical Compounds Rec: 7951/2 dt Wef: 18/05/2006 Vide PT 3921 Attn: SS & Co. Greenford, Middlesex 23/01/2008 24/11/2006 Wef: 11/10/2006 UB6 0NN, Great Britain MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Wef: 24/11/2005 Centre Industriel, 1267 Filing Date: 24/11/2006 Erythropoietin Plypeptides Laboratoires Serono S.A. Wef: 22/12/2005 Warrant signed on 3922 Coinsins, Vaud, Rec: 7989/90 dt Vide PT 3922 and Uses Thereof Attn: CC Advocates Wef: 24/11/2005 23/01/2008 Switzerland 27/11/2006 Wef: 22/12/2005

New Combination Dosage AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 28/11/2006 Wef: 30/11/2005 Warrant signed on 3923 Vide PT 3923 Form Attn: SS & Co. Sweden Rec: 8027/8 dt 28/11/2006 Wef: 06/07/2006 23/01/2008

Ramsgate Road, Pfizer Limited Filing Date: 28/11/2006 Wef: 02/12/2005 Warrant signed on 3924 Spirocyclic Derivatives Sandwich, Kent CT13 Vide PT 3924 Attn: SS & Co. Rec: 8030/1 dt 28/11/2006 Wef: 10/04/2006 03/01/2008 9NJ, England

Formulations of Novartis AG Lichtstrasse 35, 4056 Filing Date: 29/11/2006 Wef: 29/11/2005 Warrant signed on 3925 Vide PT 3925 Quinolinones Attn: SS & Co. Basel, Switzerland Rec: 8050/1 dt 29/11/2006 Wef: 01/12/2005 23/01/2008

126 East Lincoln Merck & Co. Inc. Filing Date: 29/11/2006 Warrant signed on 3926 P38 Kinase Inhibiting Agents Avenue, Rahway, NK Wef: 05/12/2005 Vide PT 3926 Attn: CC Advocates Rec: 8098/9 dt 04/12/2006 03/01/2008 07065, U.S.A.

Use of a compound comprising a camptothecin Menarini International derivative for preparing 1 Avenue de la Gare, Filing Date: 30/11/2006 Warrant signed on 3927 Operations Luxembourg S.A. Wef: 02/12/2005 Vide PT 3927 pharmaceutical formulations 1611 Luxembourg Rec: 8071/2 dt 01/12/2006 03/01/2008 Attn: SS & Co. useful in the treatment of melanoma

Oxazolidinone compounds and their use as AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 30/11/2006 Warrant signed on 3928 Wef: 15/12/2005 Vide PT 3928 metabotropic glutamate Attn: SS & Co. Sweden Rec: 8074/5 dt 01/12/2006 03/01/2008 receptor potentiators

One Amgen Center Uses of Myostatin Amgen Inc. Drive, Thousand Oaks, Filing Date: 01/12/2006 Warrant signed on 3929 Wef: 06/12/2005 Vide PT 3929 Antagonists Attn: MAMO TCV Advocates California 91320-1799, Rec: 8085/6 dt 01/12/2006 11/12/2007 U.S.A.

41 Pinelawn Road, Bicyclic protein kinase OSI Pharmaceticals Inc. Filing Date: 04/12/2006 Warrant signed on 3930 Melville, NY 11747, Wef: 02/12/2005 Vide PT 3930 inhibitors Attn: MAMO TCV Advocates Rec: 8142/3 dt 05/12/2006 11/12/2007 U.S.A.

126 East Lincoln Polymorphs of an Androgen Merck & Co. Inc. Filing Date: 04/12/2006 Warrant signed on 3931 Avenue, Rahway, NK Wef: 07/12/2005 Vide PT 3931 Receptor Modulators Attn: CC Advocates Rec: 8145/6 dt 05/12/2006 11/12/2007 07065, U.S.A.

Novartis AG Lichtstrasse 35, 4056 Filing Date: 05/12/2006 Warrant signed on 3932 Organic Compounds Wef: 09/12/2005 Vide PT 3932 Attn: SS & Co. Basel, Switzerland Rec: 8148/9 dt 05/12/2006 11/12/2007 Novartis AG Lichtstrasse 35, 4056 Filing Date: 05/12/2006 Warrant signed on 3933 Organic Compounds Wef: 08/12/2005 Vide PT 3933 Attn: SS & Co. Basel, Switzerland Rec: 8150/1 dt 05/12/2006 11/12/2007

Novartis AG Lichtstrasse 35, 4056 Filing Date: 05/12/2006 Warrant signed on 3934 Organic Compounds Wef: 08/12/2005 Vide PT 3934 Attn: SS & Co. Basel, Switzerland Rec: 8153/4 dt 05/12/2006 11/12/2007

Salts, Prodrugs and Formulations of 1-[5-(4-amino- Eastern Point Road, 7-isopropyl-7H-pyrrolo[2,3- Pfizer Products Inc. Filing Date: 05/12/2006 Warrant signed on 3935 Groton, Connecticut Wef: 09/12/2005 Vide PT 3935 d]pyrimidine-5-carbonyl)-2- Attn: SS & Co. Rec: 8156/7 dt 05/12/2006 03/01/2008 06340, U.S.A. methoxy-phenyl]-3-(2,3- dichloro-phenyl)-urea

One Amgen Center Polishing Steps used in Multi- Amgen Inc. Drive, Thousand Oaks, Filing Date: 06/12/2006 Warrant signed on 3936 Step Protein Purifiction Wef: 06/12/2005 Vide PT 3936 Attn: MAMO TCV Advocates California 91320-1799, Rec: 8224/5 dt 07/12/2006 03/01/2008 Processes U.S.A.

Novartis AG Lichtstrasse 35, 4056 Filing Date: 07/12/2006 Warrant signed on 3937 Organic Compounds Wef: 09/12/2005 Vide PT 3937 Attn: SS & Co. Basel, Switzerland Rec: 8207/8 dt 07/12/2006 03/01/2008

New Compounds for the AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 07/12/2006 Warrant signed on 3938 Treatment of Cardiac Wef: 15/12/2005 Vide PT 3938 Attn: SS & Co. Sweden Rec: 8221/2 dt 07/12/2006 03/01/2008 Arrhythmias

Wef: 15/12/2005 AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 07/12/2006 Warrant signed on 3939 Novel Compounds Wef: 13/04/2006 Vide PT 3939 Attn: SS & Co. Sweden Rec: 8218/9 dt 07/12/2006 03/01/2008 Wef: 26/07/2006

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 07/12/2006 Warrant signed on 3940 Combinations Wef: 15/12/2005 Vide PT 3940 Attn: SS & Co. Sweden Rec: 8215/6 dt 07/12/2006 03/01/2008

Wef: 13/12/2005 Binding Proteins Specific for AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 07/12/2006 Wef: 14/12/2005 Warrant signed on 3941 Insulin-like Growth Factors Vide PT 3941 Attn: SS & Co. Sweden Rec: 8212/3 dt 07/12/2006 Wef: 17/02/2006 03/01/2008 and uses thereof Wef: 24/05/2006

41 Pinelawn Road, Filing Date: 07/12/2006 Pyrrolopyridine Kinase OSI Pharmaceuticals Inc. Warrant signed on 3942 Melville, NY 11747, Rec: 8209/10 dt Wef: 07/12/2005 Vide PT 3942 Inhibiting Compounds Attn: SS & Co. 03/01/2008 U.S.A. 07/12/2006 Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 07/12/2006 Warrant signed on 3943 Novel Forms Wef: N/A Vide PT 3943 Attn: SS & Co. Greenford, Middlesex Rec: 8205/6 dt 07/12/2006 23/10/2008 UB6 0NN, Great Britain

One Amgen Center Amgen Inc. Improved Host Cells and Drive, Thousand Oaks, Filing Date: 07/12/2006 Warrant signed on 3944 Attn: Bezzina & Mifsud Wef: 08/12/2005 Vide PT 3944 Culture Methods California 91320-1799, Rec: 8237/8 dt 07/12/2006 04/01/2008 Patentbureau U.S.A.

One Amgen Center Improved Production of Amgen Inc. Drive, Thousand Oaks, Filing Date: 07/12/2006 Warrant signed on 3945 Glycoproteins Using Attn: Bezzina & Mifsud Wef: 08/12/2005 Vide PT 3945 California 91320-1799, Rec: 8234/5 dt 07/12/2006 04/01/2008 Manganese Patentbureau U.S.A.

Zone Industrielle de Wef: 09/12/2005 Method for Purifying FSH or a Ares Trading S.A. Filing Date: 07/12/2006 Warrant signed on 3947 l'Ouriettaz, CH-1170 Wef: 09/12/2005 Vide PT 3947 FSH Mutant Attn: CC Advocates Rec: 8243/4 dt 11/12/2006 04/01/2008 Aubonne, Switzerland Wef: 04/08/2006

Quinolone Based One Amgen Center Compounds Exhibiting Prolyl Amgen Inc. Drive, Thousand Oaks, Filing Date: 09/12/2006 Wef: 09/12/2005 Warrant signed on 3948 Hydroxylase Inhibitory Attn: Bezzina & Mifsud Vide PT 3948 California 91320-1799, Rec: 8265/6 dt 11/12/2006 Wef: 24/03/2006 04/01/2008 Activity, and Compositions Patentbureau U.S.A. and Uses thereof

Compounds and Methods for 780 Memorial Drive, Inhibiting the Interaction of Infinity Pharmaceuticals Inc. Filing Date: 11/12/2006 Warrant signed on 3949 Cambridge, MA 02139, Wef: 16/12/2005 Vide PT 3949 BCL Proteins with Binding Attn: CC Advocates Rec: 8268/9 dt 11/12/2006 04/01/2008 U.S.A. Partners

Heterocyclic Derivatives, Sanofi-Aventis 174 Avenue de France, Filing Date: 12/12/2006 Warrant signed on 3950 Preparation thereof and Wef: 12/12/2005 Vide PT 3950 Attn: SS & Co. FR-75013 Paris, France Rec: 8280/1 dt 12/12/2006 04/01/2008 Therapeutic Use Thereof

Diaryltriazolmethylamine Derivatives, Preparation Sanofi-Aventis 174 Avenue de France, Filing Date: 12/12/2006 Warrant signed on 3951 Wef: 12/12/2005 Vide PT 3951 Thereof and Therapeutic Use Attn: SS & Co. FR-75013 Paris, France Rec: 8295/6 dt 12/12/2006 04/01/2008 Thereof

Orodispersible Pharmaceutical Composition 12 Place de la Defense, Les Laboratoires Servier Filing Date: 12/12/2006 Warrant signed on 3952 for Oromucosal or Sublingual F-92415 Courbevoie Wef: 14/12/2005 Vide PT 3952 Attn: SS & Co. Rec: 8292/3 dt 12/12/2006 04/01/2008 Administration of Cedex, France Agomelatine Filing Date: 12/12/2006 AstraZeneca AB SE-151 85 Sodertalje, Warrant signed on 3953 Novel Compounds Rec: 8289/90 dt Wef: 12/12/2005 Vide PT 3953 Attn: SS & Co. Sweden 04/01/2008 12/12/2006

Alkylsulphonamide AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 12/12/2006 Wef: 12/12/2005 Warrant signed on 3954 Vide PT 3954 Quinolines Attn: SS & Co. Sweden Rec: 8286/7 dt 12/12/2006 Wef: 01/08/2006 04/01/2008

Wef: 13/12/2005 GlaxoSmithKline Biologicals Rue de l'Institut 89, B- Filing Date: 12/12/2006 Wef: 18/05/2006 Warrant signed on 3955 Novel Composition s.a. 1330 Rixensart, Vide PT 3955 Rec: 8283/4 dt 12/12/2006 Wef: 12/10/2006 04/01/2008 Attn: SS & Co. Belgium Wef: 12/10/2006

Wef: 12/12/2005 Wef: 12/12/2005 Improved Synthesis and Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 12/12/2006 Wef: 12/12/2005 Warrant signed on 3956 Preparations of Duloxetine 08970 Sant Joan Despí, Vide PT 3956 Attn: SS & Co. Rec: 8324/5 dt 14/12/2006 Wef: 23/06/2006 04/01/2008 Salts Barcelona, Spain Wef: 23/06/2006 Wef: 23/06/2006

Wef: 12/12/2005 Wef: 12/12/2005 Improved Synthesis and Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 12/12/2006 Wef: 12/12/2005 Warrant signed on 3957 Preparations of Duloxetine 08970 Sant Joan Despí, Vide PT 3957 Attn: SS & Co. Rec: 8327/8 dt 14/12/2006 Wef: 23/06/2006 04/01/2008 Salts Barcelona, Spain Wef: 23/06/2006 Wef: 23/06/2006

Wef: 12/12/2005 Wef: 12/12/2005 Improved Synthesis and Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 12/12/2006 Wef: 12/12/2005 Warrant signed on 3958 Preparations of Duloxetine 08970 Sant Joan Despí, Vide PT 3958 Attn: SS & Co. Rec: 8330/1 dt 14/12/2006 Wef: 23/06/2006 04/01/2008 Salts Barcelona, Spain Wef: 23/06/2006 Wef: 23/06/2006

Treatment of Psychiatric Wef: 12/12/2005 Patients with Reduced Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 12/12/2006 Warrant signed on 3959 Wef: 20/04/2006 Vide PT 3959 Hepatic Function with Attn: EMD Advocates 2340 Beerse, Belgium Rec: 8321/2 dt 14/12/2006 04/01/2008 Wef: 22/09/2006 Paliperidone

P.O. Box 4000, Route Macrocyclic Factor VIIA 206 and Province Line Bristol-Myers Squibb Company Filing Date: 14/12/2006 Wef: 13/12/2005 Warrant signed on 3960 Inhibitors Useful as Road, Princeton, New Vide PT 3960 Attn: MAMO TCV Advocates Rec: 8352/3 dt 14/12/2006 Wef: 13/11/2006 04/01/2008 Anticoagulatns Jersey 08543-4000, U.S.A. Arylpropionamide, P.O. Box 4000, Route Arylacrylamide, 206 and Province Line Filing Date: 14/12/2006 Wef: 14/12/2005 Bristol-Myers Squibb Company Warrant signed on 3961 Arylpropynamide, or Road, Princeton, New Rec: 8349/50 dt Wef: 02/08/2006 Vide PT 3961 Attn: MAMO TCV Advocates 04/01/2008 Arylmethylurea Analogs as Jersey 08543-4000, 14/12/2006 Wef: 10/11/2006 Factor XIA Inhibitors U.S.A.

P.O. Box 4000, Route Six-Membered Heterocycles 206 and Province Line Bristol-Myers Squibb Company Filing Date: 14/12/2006 Warrant signed on 3962 Useful as Serine Protease Road, Princeton, New Wef: 14/12/2005 Vide PT 3962 Attn: MAMO TCV Advocates Rec: 8346/7 dt 14/12/2006 04/01/2008 Inhibitors Jersey 08543-4000, U.S.A.

Diaza Heterocyclic One Amgen Center Amgen Inc. Filing Date: 14/12/2006 Warrant signed on 3963 Sulfonamide Derivatives and Drive, Thousand Oaks, Wef: 14/12/2005 Vide PT 3963 Attn: SS & Co. Rec: 8355/6 dt 14/12/2006 07/01/2008 Their Use CA 91320-1799, U.S.A.

Centre Industriel, 1267 Laboratoires Serono S.A. Filing Date: 14/12/2006 Wef: 15/12/2005 Warrant signed on 3964 New Chemokine Antagonists Coinsins, Vaud, Vide PT 3964 Attn: CC Advocates Rec: 8376/7 dt 15/12/2006 Wef: 19/12/2005 07/01/2008 Switzerland

Filing Date: 15/12/2006 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 3965 Organic Compounds Rec: 8379/80 dt Wef: 16/12/2005 Vide PT 3965 Attn: SS & Co. Basel, Switzerland 07/01/2008 15/12/2006

235 East 42nd Street, Chromane Substituted Pfizer Inc. Filing Date: 15/12/2006 Wef: 19/12/2005 Warrant signed on 3966 New York, New York Vide PT 3966 Benzimidazole Derivatives Attn: SS & Co. Rec: 8382/3 dt 15/12/2006 Wef: 23/05/2006 07/01/2008 10017, U.S.A.

436 Cambridge Science Astex Therapeutics Ltd. & Park, Milton Road, Filing Date: 15/12/2006 Warrant signed on 3967 New Compounds AstraZeneca AB Cambridge, CB4 0QA, Wef: 19/12/2005 Vide PT 3967 Rec: 8384/5 dt 15/12/2006 07/01/2008 Attn: SS & Co. U.K. & SE-151 85 Sodertalje, Sweden

Compounds and Uses AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 15/12/2006 Wef: 20/12/2005 Warrant signed on 3968 Vide PT 3968 Thereof Attn: SS & Co. Sweden Rec: 8387/8 dt 15/12/2006 Wef: 28/08/2006 07/01/2008

Ramsgate Road, Pfizer Limited Filing Date: 15/12/2006 Warrant signed on 3969 Pyrimidine Derivatives Sandwich, Kent CT13 Wef: 20/12/2005 Vide PT 3969 Attn: SS & Co. Rec: 8390/1 dt 15/12/2006 07/01/2008 9NJ, England Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 15/12/2006 Warrant signed on 3970 Immunoglobulins Wef: 16/12/2005 Vide PT 3970 Attn: SS & Co. Greenford, Middlesex Rec: 8393/4 dt 15/12/2006 07/01/2008 UB6 0NN, Great Britain

Pyrimidine Derivatives for the Eastern Point Road, Pfizer Products Inc. Filing Date: 15/12/2006 Warrant signed on 3971 Treatment of Abnormal Cell Groton, Connecticut Wef: 21/12/2005 Vide PT 3971 Attn: SS & Co. Rec: 8396/7 dt 15/12/2006 07/01/2008 Growth 06340, U.S.A.

Preparation of gamma-amino Eastern Point Road, Filing Date: 15/12/2006 Pfizer Products Inc. Warrant signed on 3972 acids having affinity for the Groton, Connecticut Rec: 8399/400 dt Wef: 21/12/2005 Vide PT 3972 Attn: SS & Co. 07/01/2008 alpha-2-delta protein 06340, U.S.A. 15/12/2006

280 East Grand Wef: 15/12/2005 Certain Chemical Entities, Cytokinetics Inc. Avenue, South San Filing Date: 15/12/2006 Warrant signed on 3973 Wef: 04/01/2006 Vide PT 3973 Compositions and Methods Attn: SS & Co. Francisco, CA 94080, Rec: 8408/9 dt 15/12/2006 07/01/2008 Wef: 29/06/2006 U.S.A.

Use of Benzo-Fused Filing Date: 18/12/2006 Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3974 Rec: P585662 dt Wef: 19/12/2005 Vide PT 3974 Derivatives for the Treatment Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 18/12/2006 of Obesity

Use of Benzo-Fused Heterocycle Sulfamide Filing Date: 18/12/2006 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3975 Derivatives for lowering Rec: P585662 dt Wef: 19/12/2005 Vide PT 3975 Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 lipids and lowering blood 18/12/2006 glucose levels

Use of Benzo-Fused Filing Date: 18/12/2006 Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Wef: 19/12/2005 Warrant signed on 3976 Rec: P585662 dt Vide PT 3976 Derivatives for the Treatment Attn: EMD Advocates 2340 Beerse, Belgium Wef: 15/02/2006 07/01/2008 18/12/2006 of Pain

Use of Benzo-Fused Filing Date: 18/12/2006 Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3977 Rec: P585662 dt Wef: 19/12/2005 Vide PT 3977 Derivatives as Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 18/12/2006 Neuroprotective Agents

Use of Benzo-Fused Filing Date: 18/12/2006 Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3978 Rec: P585662 dt Wef: 19/12/2005 Vide PT 3978 Derivatives for Disease Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 18/12/2006 Modification/Epiliptogenesis Use of Benzo-Fused Heterocycle Sulfamide Filing Date: 18/12/200 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3979 Derivatives for the Treatment Rec: P585662 dt Wef: 19/12/2005 Vide PT 3979 Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 of Substance Abuse and 18/12/2006 Addiction

Use of Benzo-Fused Heterocycle Sulfamide Filing Date: 18/12/2006 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3980 Derivatives for the Treatment Rec: P585662 dt Wef: 19/12/2005 Vide PT 3980 Attn: EMD Advocates 2340 Beerse, Belgium 07/01/2008 of Mania and Bipolar 18/12/2006 Disorder

Use of Benzo-Fused Filing Date: 18/12/2006 Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 3981 Rec: P585662 dt Wef: 19/12/2005 Vide PT 3981 Derivatives for the Treatment Attn: EMD Advocates 2340 Beerse, Belgium 08/01/2008 18/12/2006 of Depression

Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/12/2006 Wef: 20/12/2005 Warrant signed on 3982 Organic Compounds Vide PT 3982 Attn: SS & Co. Basel, Switzerland Rec: 8543/4 dt 19/12/2006 Wef: 11/09/2006 08/01/2008

Sulphonamidoaniline Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/12/2006 Warrant signed on 3983 Derivatives being Janus Wef: 22/12/2005 Vide PT 3983 Attn: SS & Co. Basel, Switzerland Rec: 8541 dt 19/12/2006 08/01/2008 Kinases Inhibitors

Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/12/2006 Warrant signed on 3984 Organic Compounds Wef: 22/12/2005 Vide PT 3984 Attn: SS & Co. Basel, Switzerland Rec: 8538/9 dt 19/12/2006 08/01/2008

Sustained release formulation comprising Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/12/2006 Wef: 22/12/2005 Warrant signed on 3985 octreotide and two or more Vide PT 3985 Attn: SS & Co. Basel, Switzerland Rec: 8535/6 dt 19/12/2006 Wef: 17/08/2006 08/01/2008 polylactide-co-glycolide polymers

One Franklin Plaza, SmithKline Beecham P.O. Box 7929, Filing Date: 19/12/2006 Wef: 22/12/2005 Warrant signed on 3986 Compounds Corporation Vide PT 3986 Philadelphia, PA 19101, Rec: 8532/3 dt 19/12/2006 Wef: 21/04/2006 08/01/2008 Attn: SS & Co. U.S.A.

Glaxo Wellcome House, Filing Date: 19/12/2006 Glaxo Group Limited Berkeley Avenue, Wef: 20/12/2005 Warrant signed on 3987 Compounds Rec: 8529/30 dt Vide PT 3987 Attn: SS & Co. Greenford, Middlesex Wef: 21/11/2006 08/01/2008 19/12/2006 UB6 0NN, Great Britain

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 19/12/2006 Wef: 22/12/2005 Warrant signed on 3988 Compounds Vide PT 3988 Attn: SS & Co. Greenford, Middlesex Rec: 8526/7 dt 19/12/2006 Wef: 22/11/2006 23/01/2008 UB6 0NN, Great Britain New Heterocyclic Oxime Compounds, Process for 12, Place de la their preparation and Les Laboratoires Servier Defense, F-92415 Filing Date: 19/12/2006 Warrant signed on 3989 Wef: 20/12/2005 Vide PT 3989 Pharmaceutical Attn: SS & Co. Courbevoie Cedex, Rec: 8523/4 dt 19/12/2006 08/01/2008 Compositions Containing France Them

Wef: 22/12/2005 Wef: 07/04/2006 Wef: 07/04/2006 GlaxoSmithKline Biologicals rue de l'Institut 89, B- Filing Date: 19/12/2006 Wef: 18/05/2006 Warrant signed on 3990 Vaccine s.a. 1330 Rixensart, Vide PT 3990 Rec: 8520/1 dt 19/12/2006 Wef: 12/10/2006 08/01/2008 Attn: SS & Co. Belgium Wef: 12/10/2006 Wef: 19/10/2006 Wef: 19/10/2006

New Pharmaceutical 12, Place de la Composition based on an Les Laboratoires Servier Defense, F-92415 Filing Date: 19/12/2006 Warrant signed on 3991 Wef: 23/12/2005 Vide PT 3991 essential oil for nasal and/or Attn: SS & Co. Courbevoie Cedex, Rec: 8517/8 dt 19/12/2006 08/01/2008 buccal spraying France

Eastern Point Road, Pfizer Products Inc. Filing Date: 19/12/2006 Wef: 22/12/2005 Warrant signed on 3992 Estrogen Modulators Groton, Connecticut Vide PT 3992 Attn: SS & Co. Rec: 8514/5 dt 19/12/2006 Wef: 20/06/2006 08/01/2008 06340, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 19/12/2006 Warrant signed on 3993 Chemical Compounds Wef: 22/12/2005 Vide PT 3993 Attn: SS & Co. Sweden Rec: 8511/2 dt 19/12/2006 08/01/2008

Eastern Point Road, Pfizer Products Inc. Filing Date: 19/12/2006 Warrant signed on 3994 Antibacterial Agents Groton, Connecticut Wef: 22/12/2005 Vide PT 3994 Attn: SS & Co. Rec: 8508/9 dt 19/12/2006 08/01/2008 06340, U.S.A.

3200 Walnut Street, Array Biopharma Inc. & Boulder, Colorado Filing Date: 19/12/2006 Warrant signed on 3995 Novel Hydrogen Sulfate Salt AstraZeneca AB Wef: 21/12/2005 Vide PT 3995 80301, U.S.A. & SE-151 Rec: 8505/6 dt 19/12/2006 08/01/2008 Attn: SS & Co. 85 Sodertalje, Sweden

Eastern Point Road, Pfizer Products Inc. Filing Date: 19/12/2006 Warrant signed on 3996 Piperidine Derivatives Groton, Connecticut Wef: 20/12/2005 Vide PT 3996 Attn: SS & Co. Rec: 8502/3 dt 19/12/2006 08/01/2008 06340, U.S.A.

P.O. Box 4000, Route 206 and Province Line Bristol-Myers Squibb Company Filing Date: 19/12/2006 Warrant signed on 3997 Stable Protein Formulations Road, Princeton, New Wef: 20/12/2005 Vide PT 3997 Attn: MAMO TCV Advocates Rec: 8564/5 dt 19/12/2006 08/01/2008 Jersey 08543-4000, U.S.A. P.O. Box 4000, Route 206 and Province Line Wef: 20/12/2005 Compositions and Methods Bristol-Myers Squibb Company Filing Date: 19/12/2006 Warrant signed on 3998 Road, Princeton, New Wef: 20/12/2005 Vide PT 3998 for Producing a Composition Attn: MAMO TCV Advocates Rec: 8665/6 dt 22/12/2006 08/01/2008 Jersey 08543-4000, Wef: 05/10/2006 U.S.A.

Wef: 19/12/2005 Wef: 27/12/2005 Wef: 23/01/2006 Wef: 15/02/2006 Wef: 07/03/2006 Compositions and Methods Sicor Inc. 19 Hughes, Irvine, Filing Date: 19/12/2006 Wef: 20/07/2006 Warrant signed on 3999 Vide PT 3999 for Producing a Composition Attn: CC Advocates California 92618, U.S.A. Rec: 8570/1 dt 20/12/2006 Wef: 03/08/2006 08/01/2008 Wef: 03/08/2006 Wef: 07/08/2006 Wef: 10/07/2006 Wef: 12/10/2006 Wef: 18/10/2006

Wef: 19/12/2005 Wef: 27/12/2005 Wef: 23/01/2006 Novel Forms of Tiotroium Sicor Inc. 19 Hughes, Irvine, Filing Date: 19/12/2006 Wef: 15/02/2006 Warrant signed on 4000 Bromide and Processes for Vide PT 4000 Attn: CC Advocates California 92618, U.S.A. Rec: 8567/8 dt 20/12/2006 Wef: 07/03/2006 08/01/2008 Preparation Thereof Wef: 20/07/2006 Wef: 12/10/2006 Wef: 18/10/2006

Wef: 22/12/2005 Wef: 07/04/2006 Wef: 07/04/2006 GlaxoSmithKline Biologicals rue de l'Institut 89, B- Filing Date: 19/12/2006 Wef: 18/05/2006 Warrant signed on 4001 Vaccine s.a. 1330 Rixensart, Rec: 8589/90 dt Vide PT 4001 Wef: 12/10/2006 08/01/2008 Attn: SS & Co. Belgium 20/12/2006 Wef: 12/10/2006 Wef: 19/10/2006 Wef: 19/10/2006

Wef: 22/12/2005 Wef: 07/04/2006 Wef: 07/04/2006 GlaxoSmithKline Biologicals rue de l'Institut 89, B- Filing Date: 19/12/2006 Wef: 18/05/2006 Warrant signed on 4002 Vaccine s.a. 1330 Rixensart, Vide PT 4002 Rec: 8592/3 dt 20/12/2006 Wef: 12/10/2006 08/01/2008 Attn: SS & Co. Belgium Wef: 12/10/2006 Wef: 19/10/2006 Wef: 19/10/2006 Experimental Station, 3- Route 141 & Henry Clay aminocyclopentanecarboxam Incyte Corporation Filing Date: 20/12/2006 Wef: 21/12/2005 Warrant signed on 4003 Road, Building E336, Vide PT 4003 ides as modulators of Attn: SS & Co. Rec: 8573/4 dt 20/12/2006 Wef: 21/12/2005 09/01/2008 Wilmington, Delaware chemokine receptors 19880, U.S.A.

Novel Substituted Pyrazinone Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 20/12/2006 Warrant signed on 4004 Derivatives for Use in MCH-1 Wef: 21/12/2005 Vide PT 4004 Attn: EMD Advocates 2340 Beerse, Belgium Rec: 8576/7 dt 20/12/2006 09/01/2008 Mediated Diseases

Substituted Pyrazinone Filing Date: 20/12/2006 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Warrant signed on 4005 Derivatives for Use as a Rec: 8579/80 dt Wef: 21/12/2005 Vide PT 4005 Attn: EMD Advocates 2340 Beerse, Belgium 09/01/2008 Medicine 20/12/2006

Triazolopyridazines as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 20/12/2006 Warrant signed on 4006 Wef: 21/12/2005 Vide PT 4006 Kinase Modulators Attn: EMD Advocates 2340 Beerse, Belgium Rec: 8582/3 dt 20/12/2006 09/01/2008

Substituted Pyrimidinyl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B- Filing Date: 20/12/2006 Warrant signed on 4007 Wef: 21/12/2005 Vide PT 4007 Oxime Kinase Inhibitors Attn: EMD Advocates 2340 Beerse, Belgium Rec: 8585/6 dt 20/12/2006 08/01/2008

1214 S. University Materials and Methods for The Regents of the University of Avenue, 2nd Floor, Ann Filing Date: 20/12/2006 Warrant signed on 4008 Treating Chronic Fibrotic Michigan Attn: Wef: 23/12/2005 Vide PT 4008 Arbor, Michigan 48104- Rec: 8605/6 dt 20/12/2006 08/01/2008 Disease Bezzina & Mifsud Patentbureau 2592, U.S.A.

New Association of a Sinus Node I Current Inhibitor and 12, Place de la an Angiotensin-Converting Les Laboratoires Servier Defense, F-92415 Filing Date: 21/12/2006 Warrant signed on 4009 Wef: 21/12/2005 Vide PT 4009 Enzyme Inhibitor, and Attn: SS & Co. Courbevoie Cedex, Rec: 8404/5 dt 22/12/2006 08/01/2008 Pharmaceutical France Compositions containing it

New Association of a Sinus 12, Place de la Node I Current Inhibitor and a Les Laboratoires Servier Defense, F-92415 Filing Date: 21/12/2006 Warrant signed on 4010 Calcium Inhibitor, and Wef: 21/12/2005 Vide PT 4010 Attn: SS & Co. Courbevoie Cedex, Rec: 8701/2 dt 22/12/2006 08/01/2008 Pharmaceutical France Compositions Containing It

Imidazole Derivatives for the AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 21/12/2006 Warrant signed on 4011 Treatment of Gastrointestinal Wef: 23/12/2005 Vide PT 4011 Attn: SS & Co. Sweden Rec: 8695/9 dt 22/12/2006 08/01/2008 Disorders P.O. Box 4000, Route Indane Modulators of 206 and Province Line Glucocorticoid Receptor, AP- Bristol-Myers Squibb Company Filing Date: 21/12/2006 Wef: 21/12/2005 Warrant signed on 4012 Road, Princeton, New Vide PT 4012 1, and/or NF-KB Activity and Attn: MAMO TCV Advocates Rec: 8615/6 dt 21/12/2006 Wef: 20/12/2006 23/01/2008 Jersey 08543-4000, Use Thereof U.S.A.

One Franklin Plaza, SmithKline Beecham Filing Date: 22/12/2006 Azaindole Inhibitors of P.O. Box 7929, Warrant signed on 4013 Corporation Rec: 8729/30 dt Wef: 23/12/2005 Vide PT 4013 Aurora Kinases Philadelphia, PA 19101, 09/01/2008 Attn: SS & Co. 26/12/2006 U.S.A.

GABA-B Receptor AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/12/2006 Warrant signed on 4014 Wef: 23/12/2005 Vide PT 4014 Modulators Attn: SS & Co. Sweden Rec: 8732/3 dt 26/12/2006 08/01/2008

Imidazoles as GABA-B AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/12/2006 Warrant signed on 4015 Wef: 23/12/2005 Vide PT 4015 Receptor Modulators Attn: SS & Co. Sweden Rec: 8735/6 dt 26/12/2006 09/01/2008

Heterocyclic GABA-B AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/12/2006 Warrant signed on 4016 Wef: 23/12/2005 Vide PT 4016 Receptor Modulators Attn: SS & Co. Sweden Rec: 8738/9 dt 26/12/2006 09/01/2008

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/12/2006 Warrant signed on 4017 New Compounds III Wef: 23/12/2005 Vide PT 4017 Attn: SS & Co. Sweden Rec: 8741/2 dt 26/12/2006 09/01/2008

Pyrazoles for the treatment of AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 22/12/2006 Warrant signed on 4018 Wef: 23/12/2005 Vide PT 4018 GERD and IBS Attn: SS & Co. Sweden Rec: 8662/3 dt 22/12/2006 09/01/2008

Sulfoximine-substituted pyrimidines, processes for Schering AG Filing Date: 22/12/2006 Wef: 22/12/2005 Warrant signed on 4019 Berlin 13342, Germany Vide PT 4019 production thereof and use Attn: MAMO TCV Advocates Rec: 8685/6 dt 22/12/2006 Wef: 30/06/2006 09/01/2008 thereof as drugs

Diamine Derivatives as Schering Aktiengesellschaft Filing Date: 22/12/2006 Wef: 29/12/2005 Warrant signed on 4020 Inhibitors of Leukotriene A4 Berlin 13342, Germany Vide PT 4020 Attn: MAMO TCV Advocates Rec: 8688/9 dt 22/12/2006 Wef: 04/08/2006 08/01/2008 Hydrolase

Amide Inhibitors of Schering Aktiengesellschaft Filing Date: 22/12/2006 Wef: 29/12/2005 Warrant signed on 4021 Berlin 13342, Germany Vide PT 4021 Leukotriene A4 Hydrolase Attn: MAMO TCV Advocates Rec: 8691/2 dt 22/12/2006 Wef: 04/08/2006 09/01/2008

Nitrogen-containing Bicyclic One Amgen Center Amgen Inc. Filing Date: 22/12/2006 Wef: 23/12/2005 Warrant signed on 4022 Heteroaryl Compounds and Drive, Thousand Oaks, Vide PT 4022 Attn: CC Advocates Rec: 8707 dt 22/12/2006 Wef: 20/12/2006 03/01/2008 Methods of Use CA 91320-1799, U.S.A. MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Improved Synthesis and Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 22/12/2006 Warrant signed on 4023 Preparations of Metroprolol 08970 Sant Joan Despí, Wef: 23/12/2005 Vide PT 4023 Attn: SS & Co. Rec: 8744/5 dt 26/12/2006 23/01/2008 and Its Salts Barcelona, Spain

Crystalline Polymorphic Fructuós Gelabert, 6-8, Filing Date: 22/12/2006 Forms of Olopatadine Medichem S.A. Warrant signed on 4024 08970 Sant Joan Despí, Rec: 8747/53 dt Wef: 22/12/2005 Vide PT 4024 Hydrochloride and Processes Attn: SS & Co. 10/01/2008 Barcelona, Spain 22/12/2006 for their preparation

Processes for Preparing Fructuós Gelabert, 6-8, Intermediate Compounds Medichem S.A. Filing Date: 22/12/2006 Warrant signed on 4025 08970 Sant Joan Despí, Wef: 22/12/2005 Vide PT 4025 Useful for the Preparations of Attn: SS & Co. Rec: 8750/1 dt 26/12/2006 10/01/2008 Barcelona, Spain Ezetimibe

Novartis AG Lichtstrasse 35, 4056 Filing Date: 26/12/2006 Warrant signed on 4026 PDF Inhibitors Wef: 30/12/2005 Vide PT 4026 Attn: SS & Co. Basel, Switzerland Rec: 8723/4 dt 26/12/2006 10/01/2008

3,4-Dihydrobenzoxazine 2-1, Toranomon 2-chome, Filing Date: 27/12/2006 Compounds and Inhibitors of Japan Tobacco Inc. Warrant signed on 4027 Minato-ku, Tokyo 105- Rec: 8769/70 dt Wef: 28/12/2005 Vide PT 4027 Vanilloid Receptor Subty Pe 1 Attn: SS & Co. 03/07/2008 8422, Japan 27/12/2006 (UR1) Activity

Prokineticin 1 Receptor Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 28/12/2006 Warrant signed on 4028 Wef: 29/12/2005 Vide PT 4028 Antagonists Attn: EMD Advocates Beerse, Belgium Rec: 24/25 dt 03/01/2007 10/01/2008

Prokineticin 2 Receptor Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 28/12/2006 Warrant signed on 4029 Wef: 29/12/2005 Vide PT 4029 Antagonists Attn: EMD Advocates Beerse, Belgium Rec: 27/28 dt 03/01/2007 11/12/2007

Wef: 30/12/2005 Novartis AG Lichtstrasse 35, 4056 Filing Date: 29/12/2006 Warrant signed on 4030 Organic Compounds Wef: 02/03/2006 Vide PT 4030 Attn: SS & Co. Basel, Switzerland Rec: 21/22 dt 03/01/2007 11/12/2007 Wef: 08/06/2006

Piperzines and Piperidines as AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 29/12/2006 Warrant signed on 4031 Wef: 17/01/2006 Vide PT 4031 mGluR5 Potentiators Attn: SS & Co. Sweden Rec: 19/20 dt 03/01/2007 14/07/2008

Yeda Research and Weizmann Institute of Inhibition of CXCR4 and/or Filing Date: 29/12/2006 Warrant signed on 4032 Development Co. Ltd. Science, P.O. Box 95, Wef: 29/12/2005 Vide PT 4032 Cell Motility Rec: 07/08 dt 03/01/2007 11/12/2007 Attn: CC Advocates Rehovot 76100, Israel

Bicyclic Heteroaryl Eastern Point Road, Pfizer Products Inc. Filing Date: 02/01/2007 Warrant signed on 4033 Compounds as PDE10 Groton, Connecticut Wef: 05/01/2006 Vide PT 4033 Attn: SS & Co. Rec: 10/11 dt 03/01/2007 01/08/2008 Inhibitors 06340, U.S.A. AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 02/01/2007 Warrant signed on 4034 Compounds Wef: 06/01/2006 Vide PT 4034 Attn: SS & Co. Sweden Rec: 13/14 dt 03/01/2007 01/08/2008

Bunsenstrasse 1, 82152 Martinsried, Germany & Antibodies directed to HER-3 U3 Pharma GmbH & Amgen Inc. Filing Date: 02/01/2007 Warrant signed on 4035 One Amgen Center Drive, Wef: 30/12/2005 Vide PT 4035 and uses thereof Attn: GS Services Ltd. Rec: 100/1 dt 04/01/2007 03/07/2008 Thousand Oaks, CA 91320- 1799, U.S.A.

Methods and Compositions Biomarin Pharmaceutical Inc. 105 Digital Drive, Novato, Filing Date: 02/01/2007 Wef: 03/02/2006 Warrant signed on 4036 for the Treatment of Vascular Attn: Bezzina & Mifsud Vide PT 4036 California 94949, U.S.A. Rec: 16/17 dt 03/01/2007 Wef: 30/06/2006 08/07/2008 Disease Patentbureau

Methods and Systems for Isolating Target Molecules One Amgen Center Drive, from Complex Solutions by Amgen Inc. Filing Date: 05/01/2007 Warrant signed on 4038 Thousand Oaks, CA 91320- Wef: 06/01/2006 Vide PT 4038 Column-Chromatography Attn: MAMO TCV Advocates Rec: 129/30 dt 08/01/2007 01/08/2008 1799, U.S.A. Using Eluants Containing Organic Solvents

P.O. Box 4000, Route 206 Process for the Preparation of Bristol-Myers Squibb Company and Province Line Road, Filing Date: 05/01/2007 Warrant signed on 4039 Wef: 09/01/2006 Vide PT 4039 Substituted Heterocycles Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 158/9 dt 08/01/2007 01/08/2008 08543-4000, U.S.A.

Methods for Preventing and Novartis AG & Xoma Lichtstrasse 35, 4056 Treating Cancer Metastasis Technology Ltd. Basel, Switzerland & 2910 Filing Date: 05/01/2007 Warrant signed on 4040 Wef: 05/01/2006 Vide PT 4040 and Bone Loss Associated Attn: Bezzina & Mifsud Seventh Street, Berkeley, Rec: 176/7 dt 09/01/2007 01/08/2008 with Cancer Metastasis Patenbureau California 94710, U.S.A.

Photostable pharmaceutical composition containing Berlin-Chemie AG Glienicker Weg 125, Berlin, Filing Date: 09/01/2007 Warrant signed on 4041 Wef: N/A Vide PT 4041 brivudine for the treatment of Attn: Dr. Alex Perici Calascione Germany Rec: 170/1 dt 09/01/2007 08/07/2008 herpetic keratitis

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 09/01/2007 Warrant signed on 4043 Immunoglobulins Wef: 11/01/2006 Vide PT 4043 Attn: SS & Co. Greenford, Middlesex UB6 Rec: 187/8 dt 09/01/2007 01/08/2008 0NN, Great Britain

Urotensin II Receptor Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 09/01/2007 Warrant signed on 4044 Wef: 10/01/2006 Vide PT 4044 Antagonists Attn: EMD Advocates Beerse, Belgium Rec: 173/4 dt 09/01/2007 01/08/2008 Human Glucagon-like-peptide- P.O. Box 4000, Route 206 Wef: 11/01/2006 1 Modulators and their use in Bristol-Myers Squibb Company and Province Line Road, Filing Date: 10/01/2007 Wef: 11/01/2006 Warrant signed on 4045 Vide PT 4045 the treatment of diabetes and Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 192/3 dt 10/01/2007 Wef: 11/01/2006 01/08/2008 related conditions 08543-4000, U.S.A. Wef: 11/01/2006

Siva Ubiquitination and/or Yeda Research and Weizmann Institute of Filing Date: 11/01/2007 Warrant signed on 4046 Degradation-related Activity Development Co. Ltd. Science, P.O. Box 95, Wef: 12/01/2006 Vide PT 4046 Rec: 222/3 dt 12/01/2007 01/08/2008 and Modulators thereof Attn: CC Advocates Rehovot 76100, Israel

Methods for Modulating One Amgen Center Drive, Amgen Inc. Filing Date: 11/01/2007 Wef: 23/01/2006 Warrant signed on 4047 Mannose Content of Thousand Oaks, CA 91320- Vide PT 4047 Attn: CC Advocates Rec: 219/20 dt 12/01/2007 Wef: 22/02/2007 01/08/2008 Recombinant Proteins 1799, U.S.A.

One Amgen Center Drive, Thiazole Compounds and Amgen Inc. Filing Date: 11/01/2007 Warrant signed on 4048 Thousand Oaks, CA 91320- Wef: 18/01/2006 Vide PT 4048 Methods of Use Attn: CC Advocates Rec: 215/6 dt 12/01/2007 03/07/2008 1799, U.S.A.

Hurst Holme, 12 Trott Methods and Compositions IRM LLC Filing Date: 12/01/2007 Warrant signed on 4049 Road, Hamilton, Bermuda Wef: 13/01/2006 Vide PT 4049 for Treating Allergic Diseases Attn: SS & Co. Rec: 227/8 dt 12/01/2007 03/07/2008 HM11

Sanofi-Pasteur 2, Avenue Pont Pasteur, F- Filing Date: 12/01/2007 Warrant signed on 4051 Dengue Chimeric Viruses Wef: 13/01/2006 Vide PT 4051 Attn: SS & Co. 69007, Lyon Rec: 233/4 dt 12/01/2007 03/07/2008

Compositions and Methods of Novartis AG Lichtstrasse 35, 4056 Filing Date: 12/01/2007 Warrant signed on 4052 Use for Antibodies of Wef: 13/01/2006 Vide PT 4052 Attn: SS & Co. Basel, Switzerland Rec: 236/7 dt 12/01/2007 03/07/2008 Dickkopf-1

Ronda del General Mitre Phenoxy-Substituted Laboratorios Almirall, S.A. & 151, Barcelona 08022, Filing Date: 15/01/2007 Warrant signed on 4053 Pyrimidines as Adenonsine Neurocrine Biosciences, Inc. Spain & 12790 El Camino Wef: 17/01/2006 Vide PT 4053 Rec: 301/2 dt 16/01/2007 03/07/2008 Receptor Antagonists Attn: MAMO TCV Advocates Real, San Diego, CA 92130, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 16/01/2007 Warrant signed on 4054 Chemical Compounds Wef: 17/01/2006 Vide PT 4054 Attn: SS & Co. Sweden Rec: 337/8 dt 16/01/2007 03/07/2008

6536 Kaiser Drive, Quark Biotech, Inc. & Atugen Fremont, California 94555, Wef: 20/01/2006 Therapeutic Uses of Inhibitors Filing Date: 16/01/2007 Warrant signed on 4055 AG. U.S.A. & Robert Rössle- Wef: 01/05/2006 Vide PT 4055 of RTP801 Rec: 340/2 dt 16/01/2007 03/07/2008 Attn: SS & Co. Str. 10, D-13125 Berlin, Wef: 10/10/2006 Germany

Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/01/2007 Warrant signed on 4058 Organic Compounds Wef: 23/01/2006 Vide PT 4058 Attn: SS & Co. Basel, Switzerland Rec: 440/1 dt 19/01/2007 03/07/2008 Eastgate Village, Eastgate, Long Term Treatment of HIV Tibotec Pharmaceuticals Ltd. Filing Date: 19/01/2007 Warrant signed on 4059 Little Island, Co. Cork, Wef: 20/01/2006 Vide PT 4059 Infection Attn: EMD Advocates Rec: 413/4 dt 19/01/2007 03/07/2008 Ireland

PI-3 Kinase Inhibitors and Novartis AG Lichtstrasse 35, 4056 Filing Date: 19/01/2007 Warrant signed on 4060 Wef: 20/01/2006 Vide PT 4060 Methods of Their Use Attn: CC Advocates Basel, Switzerland Rec: 449/50 dt 22/01/2007 01/08/2008

One Amgen Centre Drive, Ang2 and Vegf Inhibitor Amgen Inc. Filing Date: 19/01/2007 Warrant signed on 4061 Thousand Oaks, CA 91320- Wef: 27/01/2006 Vide PT 4061 Combinations Attn: CC Advocates Rec: 452/3 dt 22/01/2007 01/08/2008 1799, U.S.A.

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 23/01/2007 Warrant signed on 4062 Pyrimidine Derivatives Wef: 26/01/2006 Vide PT 4062 Attn: SS & Co. Sweden Rec: 469/70 dt 23/01/2007 01/08/2008

Novel Heteroaryl Substituted AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 23/01/2007 Warrant signed on 4063 Wef: 27/01/2006 Vide PT 4063 Benzothiazoles Attn: SS & Co. Sweden Rec: 472/3 dt 23/01/2007 01/08/2008

One Amgen Centre Drive, Aurora Kinase Modulators Amgen Inc. Filing Date: 23/01/2007 Wef: 23/01/2006 Warrant signed on 4064 Thousand Oaks, CA 91320- Vide PT 4064 and Method of Use Attn: CC Advocates Rec: 501/2 dt 24/01/2007 Wef: 18/01/2007 01/08/2008 1799, U.S.A.

Centre Industriel, 1267 Thiazole Derivatives and Use Laboratoires Serono SA Filing Date: 23/01/2007 Wef: 23/01/2006 Warrant signed on 4065 Coinsins, Vaud, Vide PT 4065 thereof Attn: CC Advocates Rec: 498/9 dt 24/01/2007 Wef: 27/01/2006 01/08/2008 Switzerland

SmithKline Beecham One Franklin Plaza, P.O. Filing Date: 24/01/2007 Warrant signed on 4066 Chemical Compounds Corporation Box 7929, Philadelphia PA Wef: 25/01/2006 Vide PT 4066 Rec: 495/6 dt 24/01/2007 01/08/2008 Attn: SS & Co. 19101, U.S.A.

P.O. Box 4000, Route 206 CD86 and CD80 Receptor Bristol-Myers Squibb Company and Province Line Road, Filing Date: 24/01/2007 Wef: 24/01/2006 Warrant signed on 4067 Vide PT 4067 Competition Assays Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 492/3 dt 24/01/2007 Wef: 20/07/2006 01/08/2008 08543-4000, U.S.A.

Film-shaped drug forms for Bayer Schering Pharma AG Filing Date: 24/01/2007 Warrant signed on 4068 Berlin 13342, Germany Wef: 24/01/2006 Vide PT 4068 use in the oral cavity (wafers) Attn: MAMO TCV Advocates Rec: 570/1 dt 26/01/2007 01/08/2008

OSI Pharmaceuticals Inc. 41 Pinelawn Road, Filing Date: 25/01/2007 Warrant signed on 4069 Unsaturated mTOR Inhibitors Wef: 25/01/2006 Vide PT 4069 Attn: SS & Co. Melville, NY 11747, U.S.A. Rec: 533/4 dt 25/01/2007 01/08/2008

P.O. Box 4000, Route 206 Piperidinyl Derivatives as Bristol-Myers Squibb Company and Province Line Road, Filing Date: 26/01/2007 Wef: 27/01/2006 Warrant signed on 4070 Modulators of Chemokine Vide PT 4070 Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 567/8 dt 26/01/2007 Wef: 23/01/2007 01/08/2008 Receptor Activity 08543-4000, U.S.A. P.O. Box 4000, Route 206 Piperazinyl Derivatives as Bristol-Myers Squibb Company and Province Line Road, Filing Date: 26/01/2007 Wef: 27/01/2006 Warrant signed on 4071 Modulators of Chemokine Vide PT 4071 Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 564/5 dt 26/01/2007 Wef: 23/01/2007 01/08/2008 Receptor Activity 08543-4000, U.S.A.

Modulation of MDL-1 Activity Bayer Schering Pharma AG Filing Date: 26/01/2007 Warrant signed on 4072 For Treatment of Inflammatory Berlin 13342, Germany Wef: 31/01/2006 Vide PT 4072 Attn: MAMO TCV Advocates Rec: 561/2 dt 26/01/2007 01/08/2008 Disease

Novartis AG Lichtstrasse 35, 4056 Filing Date: 30/01/2007 Warrant signed on 4073 Organic Compounds Wef: 31/01/2006 Vide PT 4073 Attn: SS & Co. Basel, Switzerland Rec: 634/5 dt 31/01/2007 01/08/2008

New Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxy Alkylene- 12, place de La Defense, F- Cyclopropanamine Les Laboratoires Servier Filing Date: 30/01/2007 Warrant signed on 4074 92415 Courbevoie Cedex, Wef: 30/01/2006 Vide PT 4074 Compounds, a Process for Attn: SS & Co. Rec: 636/7 dt 31/01/2007 01/08/2008 France their Preparation and Pharmaceutical Compositions Containing Them

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 30/01/2007 Warrant signed on 4075 A New Salt Wef: 02/02/2006 Vide PT 4075 Attn: SS & Co. Sweden Rec: 639/40 dt 31/01/2007 08/01/2008

SmithKline Beecham One Franklin Plaza, P.O. Filing Date: 30/01/2007 Warrant signed on 4076 Compounds Corporation Box 7929, Philadelphia PA Wef: 01/02/2006 Vide PT 4076 Rec: 642/3 dt 31/01/2007 08/07/2008 Attn: SS & Co. 19101, U.S.A.

Compositions and Methods One Amgen Centre Drive, Amgen Inc. Filing Date: 30/01/2007 Wef: 31/01/2006 4077 related to CD30-ligand Thousand Oaks, CA 91320- WITHDRAWN Vide PT 4077 Attn: SS & Co. Rec: 644/5 dt 31/01/2007 Wef: 13/04/2006 Antibodies 1799, U.S.A.

130 Waverly Street, Vertex Pharmaceuticals Inc. Filing Date: 31/01/2007 Wef: 02/02/2006 4078 Pharmaceutical Compositions Cambridge, Massachusetts WITHDRAWN Vide PT 4078 Attn: EMD Advocates Rec: 682/3 dt 01/02/2007 Wef: 20/03/2006 02139-4242, U.S.A.

Process for preparing Voriconazole, New Medichem S.A. Pol. Ind. Celrá, 17460 Filing Date: 01/02/2007 Wef: 01/02/2006 Warrant signed on 4079 Polymorphic Form of Vide PT 4079 Attn: CC Advocates Celrá, Girona, Spain Rec: 720/1 dt 02/02/2007 Wef: 06/07/2006 08/07/2008 Intermediate Thereof, and Uses thereof

Muenchensteinerstrasse Synthesis of Glucagon-like Lonza AG Filing Date: 01/02/2007 Warrant signed on 4080 38, 4002 Basel, Wef: 08/02/2006 Vide PT 4080 Peptide Attn: CC Advocates Rec: 717/8 dt 02/02/2007 08/07/2008 Switzerland Acid Addition Salts of N-{3-[4- (2-Methoxyphenyl)-1- Raheens East, Recordati Ireland Limited Filing Date: 02/02/2007 Warrant signed on 4081 piperazinyl]-propyl}-7-oxo-5- Ringaskiddy, Co. Cork, Wef: 03/02/2006 Vide PT 4081 Attn: SS & Co. Rec: 724/5 dt 02/02/2007 08/07/2008 trifluoromethyl-7H-thieno[3,2- Ireland b]pyran-3-carboxamide

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 02/02/2007 Wef: 03/02/2006 Warrant signed on 4082 Novel Compounds Vide PT 4082 Attn: SS & Co. Greenford, Middlesex UB6 Rec: 727/8 dt 02/02/2007 Wef: 05/05/2006 08/07/2008 0NN, Great Britain

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 06/02/2007 Warrant signed on 4084 New Compounds II Wef: 07/02/2006 Vide PT 4084 Attn: SS & Co. Sweden Rec: 772/3 dt 06/02/2007 08/07/2008

Production of Cabergoline Wedgwood Way, Resolution Chemicals Limited Filing Date: 06/02/2007 Warrant signed on 4085 and Novel Polymorphic Form Stevenage, Hertfordshire Wef: 08/02/2006 Vide PT 4085 Attn: SS & Co. Rec: 775/6 dt 06/02/2007 08/07/2008 Thereof SG1 4QT, U.K.

New Metabotropic Glutamate AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 06/02/2007 Wef: 16/02/2006 Warrant signed on 4086 Receptor-potentiating Vide PT 4086 Attn: SS & Co. Sweden Rec: 778/9 dt 06/02/2007 Wef: 22/12/2006 08/07/2008 Isoindolones

N-Phenylbenzotriazolyl c-kit OSI Pharmaceuticals Inc. 41 Pinelawn Road, Filing Date: 06/02/2007 Warrant signed on 4087 Wef: 06/02/2006 Vide PT 4087 inhibitors Attn: SS & Co. Melville, NY 11747, U.S.A. Rec: 780/1 dt 06/02/2007 08/07/2008

Therapeutic Agent for Inflammatory Bowel Disease Containing as Active 5 Kanda Surugadai 2- Kyorin Pharmaceutical Co. Ltd. Filing Date: 06/02/2007 Warrant signed on 4088 Ingredient 2-amino-1,3- chome, Chiyoda-ku, Tokyo Wef: 06/02/2006 Vide PT 4088 Attn: MAMO TCV Advocates Rec: 814/5 dt 07/02/2007 08/07/2008 propanediol derivative, or 101-8311, Japan method for treating inflammatory Bowel Disease

P.O. Box 4000, Route 206 Melanin Concentrating Bristol-Myers Squibb Company and Province Line Road, Filing Date: 06/02/2007 Warrant signed on 4089 Hormone Receptor-1 Wef: 06/02/2006 Vide PT 4089 Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 811/2 dt 07/02/2007 08/07/2008 Antagonists 08543-4000, U.S.A.

One Amgen Centre Drive, Amgen Inc. Filing Date: 07/02/2007 Warrant signed on 4091 Antibodies that bind par-2 Thousand Oaks, CA 91320- Wef: 10/02/2006 Vide PT 4091 Attn: CC Advocates Rec: 830/1 dt 08/02/2007 08/07/2008 1799, U.S.A. 8/9 Spire Green Centre, Azole Derivatives and Their Argenta Discovery Ltd Filing Date: 07/02/2007 Warrant signed on 4092 Flex Meadow, Harlow, Wef: N/A Vide PT 4092 Uses Attn: CC Advocates Rec: 827/8 dt 08/02/2007 08/07/2008 Essex CM19 5TR, U.K.

8/9 Spire Green Centre, Bicyclo[2.2.1]hept-7-ylamine Argenta Discovery Ltd Filing Date: 07/02/2007 Warrant signed on 4093 Flex Meadow, Harlow, Wef: N/A Vide PT 4093 derivatives and their use Attn: CC Advocates Rec: 824/5 dt 08/02/2007 08/07/2008 Essex CM19 5TR, U.K.

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 08/02/2007 Warrant signed on 4094 Novel Compound Wef: 10/02/2006 Vide PT 4094 Attn: SS & Co. Greenford, Middlesex UB6 Rec: 8237/9 dt 08/02/2007 08/07/2008 0NN, Great Britain

Piperidine Derivatives as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 08/02/2007 Warrant signed on 4095 Wef: 10/02/2006 Vide PT 4095 CXCR3 Receptor Antagonists Attn: EMD Advocates Beerse, Belgium Rec: 863/4 dt 08/02/2007 08/07/2008

Piperidine Derivatives as Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 08/02/2007 Warrant signed on 4096 Wef: 10/02/2006 Vide PT 4096 CXCR3 Receptor Antagonists Attn: EMD Advocates Beerse, Belgium Rec: 866/7 dt 08/02/2007 08/07/2008

SGX Pharmaceuticals Inc. Pyrrolo-Pyridine Kinase 10505 Roselle Street, San Filing Date: 09/02/2007 Warrant signed on 4097 Attn: Galea Salomone & Wef: 27/02/2006 Vide PT 4097 Modulators Diego, California, U.S.A. Rec: 1812/3 dt 05/04/2007 08/07/2008 Associates

Ramsgate Road, Wef: 17/02/2006 Pfizer Limited Filing Date: 13/02/2007 Warrant signed on 4098 Novel Pharmaceuticals Sandwich, Kent CT13 9NJ, Wef: 17/10/2006 Vide PT 4098 Attn: SS & Co. Rec: 925/7 dt 13/02/2007 08/07/2008 Great Britain Wef: 14/12/2006

AstraZeneca AB SE-151 85 Sodertalje, Filing Date: 13/02/2007 Warrant signed on 4099 Novel Radioligands Wef: 14/02/2006 Vide PT 4099 Attn: SS & Co. Sweden Rec: 929/30 dt 13/02/2007 08/07/2008

Centre Industriel, 1267 Sulfonamide Derivatives and Laboratoires Serono SA Filing Date: 13/02/2007 Wef: 13/02/2006 Warrant signed on 4100 Coinsins, Vaud, Vide PT 4100 Use Thereof Attn: CC Advocates Rec: 944/5 dt 14/02/2007 Wef: 13/02/2006 08/07/2008 Switzerland

PI-3 kinase inhibitors and Novartis AG Lichtstrasse 35, 4056 Filing Date: 13/02/2007 Wef: 14/02/2006 Warrant signed on 4101 Vide PT 4101 methods of their use Attn: CC Advocates Basel, Switzerland Rec: 941/2 dt 14/02/2007 Wef: 22/12/2006 08/07/2008

Use of TPO Peptide Compounds and Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 13/02/2007 Warrant signed on 4102 Wef: 14/02/2006 Vide PT 4102 Pharmaceutical Compositions Attn: EMD Advocates Beerse, Belgium Rec: 935/6 dt 13/02/2007 08/07/2008 in the Treatment of Anemia

2200 North Commerce Kos Life Sciences Inc. Parkway, Suite 300, Filing Date: 14/02/2007 4103 Low Flush Niacin Formulation Wef: 17/02/2006 WITHDRAWN Vide PT 4103 Attn: SS & Co. Weston, Florida 33326, Rec: 953/4 dt 14/02/2007 U.S.A. Use of Benzo-Heteraryl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4104 Sulfamide Derivatives for the Wef: 15/02/2006 Vide PT 4104 Attn: EMD Advocates Beerse, Belgium Rec: 982/3 dt 15/02/2007 08/07/2008 Treatment of Depression

Use of Benzo-Heteraryl Sulfamide Derivatives for Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4105 Wef: 15/02/2006 Vide PT 4105 lowering lipids and lowering Attn: EMD Advocates Beerse, Belgium Rec: 979/80 dt 15/02/2007 08/07/2008 blodd glucose levels

Use of Benzo-Heteraryl Filing Date: 14/02/2007 Sulfamide Derivatives for the Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Warrant signed on 4106 Rec: 977/988 dt Wef: 15/02/2006 Vide PT 4106 Treatment of Disease Attn: EMD Advocates Beerse, Belgium 08/07/2008 15/02/2007 Modification/epileptogenesis

Use of Benzo-Heteraryl Sulfamide Derivatives for the Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4107 Wef: 15/02/2006 Vide PT 4107 Treatment of Mania and Attn: EMD Advocates Beerse, Belgium Rec: 974/5 dt 15/02/2007 08/07/2008 Bipolar Disorder

Use of Benzo-Heteraryl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4108 Sulfamide Derivatives for the Wef: 15/02/2006 Vide PT 4108 Attn: EMD Advocates Beerse, Belgium Rec: 972/3 dt 15/02/2007 08/07/2008 Treatment of Migraine

Use of Benzo-Heteraryl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4109 Sulfamide Derivatives as Wef: 15/02/2006 Vide PT 4109 Attn: EMD Advocates Beerse, Belgium Rec: 969/70 dt 15/02/2007 08/07/2008 Neuroprotective Agents

Use of Benzo-Heteraryl Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4110 Sulfamide Derivatives for the Wef: 15/02/2006 Vide PT 4110 Attn: EMD Advocates Beerse, Belgium Rec: 966/7 dt 15/02/2007 08/07/2008 Treatment of Pain

Use of Benzo-Heteroaryl Sulfamide Derivatives for the Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4111 Wef: 15/02/2006 Vide PT 4111 Treatment of Substance Attn: EMD Advocates Beerse, Belgium Rec: 963 dt 15/02/2007 08/07/2008 Abuse and Addicition

Use of Benzo-Fused Heterocycle Sulfamide Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Filing Date: 14/02/2007 Warrant signed on 4112 Wef: 15/02/2006 Vide PT 4112 Derivatives for the Treatment Attn: EMD Advocates Beerse, Belgium Rec: 965 dt 15/02/2007 08/07/2008 of Migraine

Centre Industriel, 1267 Novel CC-Chemokine Laboratoires Serono SA Filing Date: 15/02/2007 Wef: 16/02/2006 Warrant signed on 4113 Coinsins, Vaud, Vide PT 4113 Antagonists Attn: CC Advocates Rec: 1011/2 dt 16/02/2007 Wef: 16/02/2006 08/07/2008 Switzerland Crystalline Forms of (3R, 4R)- P.O. Box 4000, Route 206 4-Amino-1-[[4-[(3- Bristol-Myers Squibb Company and Province Line Road, Filing Date: 16/02/2007 Warrant signed on 4114 Methoxyphenyl)Amino]Pyrrolo Wef: 16/02/2006 Vide PT 4114 Attn: MAMO TCV Advocates Princeton, New Jersey Rec: 1014/5 dt 16/02/2007 04/07/2008 [2,1-F][1,2,4]Triazin-5- 08543-4000, U.S.A. yl]Methyl]Piperidin-3-ol

Ronda del General Mitre Filing Date: 16/02/2007 New Pyridin-3-Amine Laboratorios Almirall S.A. Warrant signed on 4115 151, 08022 Barcelona, Rec: 1069/70 dt Wef: 20/02/2006 Vide PT 4115 Derivatives Attn: SS & Co. 08/07/2008 Spain 20/02/2007

2200 North Commerce Kos Life Sciences Inc. Parkway, Suite 300, Filing Date: 19/02/2007 4116 Low Flush Niacin Formulation Wef: N/A CANCELLED Vide PT 4116 Attn: SS & Co. Weston, Florida 33326, Rec: 1063/4 dt 20/02/2007 U.S.A. Novartis AG Lichtstrasse 35, 4056 Filing Date: 20/02/2007 Warrant signed on 4117 Organic Compounds Wef: 23/02/2006 Vide PT 4117 Attn: SS & Co. Basel, Switzerland Rec: 1141/2 dt 22/02/2007 04/07/2008

Glaxo Wellcome House, Glaxo Group Limited Berkeley Avenue, Filing Date: 20/02/2007 Warrant signed on 4118 Novel Compound Wef: 22/02/2006 Vide PT 4118 Attn: SS & Co. Greenford, Middlesex UB6 Rec: 1144/5 dt 22/02/2007 04/07/2008 0NN, Great Britain

4-(3-benzoylaminophenyl)-6,7- 6-10, Koishikawa 4-chome, dimethoxy-2- Eisai R&D Management Co. Ltd. Filing Date: 20/02/2007 Warrant signed on 4119 Bunkyo-ku, Tokyo 112- Wef: 21/02/2006 Vide PT 4119 methylaminoquinazolin Attn: SS & Co. Rec: 1146/7 dt 22/02/2007 04/07/2008 8088, Japan derivatives

Dosage Form and Method For 100 Abbott Park Road, Filing Date: 20/02/2007 Abbott Laboratoires Warrant signed on 4120 the Delivery of Drugs of Abbott Park, Illinois 60064- Rec: 1149/50 dt Wef: N/A Vide PT 4120 Attn: SS & Co. 04/07/2008 Abuse 6008, U.S.A. 22/02/2007

Crystalline Forms of N- Filing Date: 21/02/2007 Janssen Pharmaceutica N.V. Turnhoutseweg 30, B-2340 Warrant signed on 4121 (benzo{b}Thien-3-Ylmethyl)- Rec: P585670 dt Wef: 22/02/2006 Vide PT 4121 Attn: EMD Advocates Beerse, Belgium 04/07/2008 Sulfamide 21/02/2007

Methods for Treating Filing Date: 21/02/2007 Univeristy of Zurich Raemistrasse 71, 8006 Wef: 22/02/2006 Warrant signed on 4122 Autoimmune or Demyelinating Rec: 1116/20 dt Vide PT 4122 Attn: CC Advocates Zurich, Switzerland Wef: 18/04/2006 08/07/2008 Diseases 22/02/2007

One Amgen Center Drive, Multi-Cyclic Compounds and Amgen Inc. Filing Date: 21/02/2007 Warrant signed on 4123 Thousand Oaks, CA 91320- Wef: 24/02/2006 Vide PT 4123 Methods of Use Attn: CC Advocates Rec: 1180/1 dt 26/02/2007 04/07/2008 1799, U.S.A. MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Soluble Receptors and Filing Date: 21/02/2007 Methods for Treating Univeristy of Zurich Raemistrasse 71, 8006 Wef: 22/02/2006 Warrant signed on 4124 Rec: 1121/3 dt Vide PT 4124 Autoimmune or Demyelinating Attn: CC Advocates Zurich, Switzerland Wef: 18/04/2006 08/07/2008 22/02/2007 Diseases

Novel Crystalline Forms of Teva Pharmaceutical Industries 5 Basel Street, P.O. Box Filing Date: 21/02/2007 Wef: 21/02/2006 Warrant signed on 4125 Armodafinil and Preparation Ltd 3190, Petah Tiqva 49131, Rec: 1183/4 dt Vide PT 4125 Wef: 13/11/2006 04/07/2008 Thereof Attn: CC Advocates Israel 26/02/2007

One Amgen Center Drive, Amgen Inc. & Memory Cinnoline Derivatives as Thousand Oaks, CA 91320- Filing Date: 21/02/2007 Pharmaceuticals Corporation Wef: 21/02/2006 Warrant signed on 4126 Phosphodiesterase 10 1799, U.S.A. & 100 Philips Rec: 1160/1 dt Vide PT 4126 Attn: Bezzina & Mifsud Wef: 23/02/2006 04/07/2008 Inhibitors Parkway, Montvale, NJ 22/02/2007 Patentbureau 07645, U.S.A.

One Amgen Center Drive, Amgen Inc. & Memory Thousand Oaks, CA 91320- Filing Date: 21/02/2007 Phosphodiesterase 10 Pharmaceuticals Corporation Warrant signed on 4127 1799, U.S.A. & 100 Philips Rec: 1163/4 dt Wef: 21/02/2006 Vide PT 4127 Inhibitors Attn: Bezzina & Mifsud 04/07/2008 Parkway, Montvale, NJ 22/02/2007 Patentbureau 07645, U.S.A.

15 Stanhope Gate, London Process for preparing AstraZeneca UK Liimited & UBE W1K 1LN, United Kingdom Filing Date: 22/02/2007 Warrant signed on 4128 dibenzothiazepine Industries Ltd. & 1978-96 O-Aza Kogushi, Rec: 1152/3 dt Wef: 22/02/2006 Vide PT 4128 04/07/2008 Compounds Attn: SS & Co. Ube-shi, Yamaguchi, 755- 22/02/2007 8633, Japan

Filing Date: 23/02/2007 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 4129 New Salt Rec: 1177/8 dt Wef: 24/02/2006 Vide PT 4129 Attn: SS & Co. Basel, Switzerland 04/07/2008 26/02/2007

8-Azabicyclo[3.2.1]Octane 901 Gateway Boulevard, Filing Date: 27/02/2007 Theravance Inc. Wef: 01/03/2006 Warrant signed on 4130 Compounds as Muopioid South San Francisco, CA Rec: 1213/4 dt Vide PT 4130 Attn: SS & Co. Wef: 30/08/2006 04/09/2008 Receptor Antagonists 94080, U.S.A. 27/02/2007

β crystalline form of the arginine salt of perindopril, a 12 Place de la Defense, F- Filing Date: 27/02/2007 Les Laboratoires Servier Warrant signed on 4131 process for its preparation 92415 Courbevoie Cedex, Rec: 1216/7 dt Wef: 28/02/2006 Vide PT 4131 Attn: SS & Co. 04/07/2008 and pharmaceutical France 27/02/2007 compositions containing it α crystalline form of the arginine salt of perindopril, a 12 Place de la Defense, F- Filing Date: 27/02/2007 Les Laboratoires Servier Warrant signed on 4132 process for its preparation 92415 Courbevoie Cedex, Rec: 1218/9 dt Wef: 28/02/2006 Vide PT 4132 Attn: SS & Co. 04/07/2008 and pharmaceutical France 27/02/2007 compositions containing it

88 Mount Pleasant, Biggin Filing Date: 27/02/2007 Breath Limited Warrant signed on 4133 Nebulizer Formulation Hill, Kent TN16 3TR, Rec: 1221/2 dt Wef: 01/03/2006 Vide PT 4133 Attn: SS & Co. 04/09/2008 United Kingdom 27/02/2007

One Amgen Center Drive, Amgen Inc. & Memory Thousand Oaks, CA 91320- Filing Date: 28/02/2007 Phosphodiesterase 10 Pharmaceuticals Corporation Warrant signed on 4134 1799, U.S.A. & 100 Philips Rec: 1258/9 dt Wef: 28/02/2006 Vide PT 4134 Inhibitors Attn: Bezzina & Mifsud 04/07/2008 Parkway, Montvale, NJ 01/03/2007 Patentbureau 07645, U.S.A.

Pteridine Derivatives as a Silberstein GmbH Limited Filing Date: 01/03/2007 80 Beaconfield Road, 4135 Rinorhizoblum enhancer of Attn: PRT Patent Registration Rec: 2153/4 dt Wef: N/A REFUSED Vide PT 4135 London SE37LQ, U.K. potatoe root respiration Services & Trade Limited 23/04/2007

Kitanomaru Square, 1-13- Filing Date: 01/03/2007 Aza-Substituted Spiro Banyu Pharmaceutical Co. Ltd. Warrant signed on 4136 12, Kudankita, Chiyoda-ku, Rec: 1297/8 dt Wef: 07/03/2006 Vide PT 4136 Derivatives Attn: CC Advocates 04/09/2008 Tokyo 1028667, Japan 02/03/2007

Filing Date: 02/03/2007 Triazoles Useful in the Biolipox AB Berzelius Väg 3, Plan 5, Warrant signed on 4137 Rec: 1303/4 dt Wef: N/A Vide PT 4137 Treament of Inflammation Attn: SS & Co. Solna, SE-171 65, Sweden 12/11/2008 02/03/2007

Eastern Point Road, Filing Date: 06/03/2007 Dibenzyl Amine Compounds Pfizer Products Inc. Wef: 10/03/2006 Warrant signed on 4138 Groton, Connecticut Rec: 1360/1 dt Vide PT 4138 and Derivatives Attn: SS & Co. Wef: 03/01/2007 04/09/2008 06340, U.S.A. 07/03/2007

Eastern Point Road, Filing Date: 06/03/2007 Dibenzyl Amine Compounds Pfizer Products Inc. Wef: 10/03/2006 Warrant signed on 4139 Groton, Connecticut Rec: 1363/4 dt Vide PT 4139 and Derivatives Attn: SS & Co. Wef: 03/01/2007 04/09/2008 06340, U.S.A. 07/03/2007

P.O. Box 4000, Route 206 Pyrrolotriazine Aniline Filing Date: 07/03/2007 Bristol-Myers Squibb Company and Province Line Road, Warrant signed on 4140 Prodrug Compounds Useful Rec: 1366/7 dt Wef: 07/03/2006 Vide PT 4140 Attn: MAMO TCV Advocates Princeton, New Jersey 04/09/2008 as Kinase Inhibitors 07/03/2007 08543-4000, U.S.A. Process for the Preparation of Intermediates of Filing Date: 08/03/2007 Medichem S.A. Pol. Ind. Celrà, 17460 Warrant signed on 4141 Rosiglitazone, Rosiglitazone Rec: 1400/1 dt Wef: 08/03/2006 Vide PT 4141 Attn: CC Advocates Celrà, Girona, Spain 04/09/2008 and New Polymorphic Forms 09/03/2007 Thereof

235 East 42nd Street, New Filing Date: 13/03/2007 Pfizer Inc. Wef: 17/03/2006 Warrant signed on 4143 Chromane Derivatives York, New York 10017, Rec: 1455/6 dt Vide PT 4143 Attn: SS & Co. Wef: 15/06/2006 04/09/2008 U.S.A. 13/03/2007

Ramsgate Road, Filing Date: 16/03/2007 Pfizer Limited Wef: 20/03/2006 Warrant signed on 4144 Amine Derivatives Sandwich, Kent CT13 9NJ, Rec: 1513/4 dt Vide PT 4144 Attn: SS & Co. Wef: 02/06/2006 04/09/2008 U.K. 16/03/2007

4 Maguire Road, Filing Date: 21/03/2007 S1P Receptor Modulating Epix Delaware Inc. Wef: 21/03/2006 Warrant signed on 4145 Lexington, MA 02421, Rec: 1560/1 dt Vide PT 4145 Compounds and Use Thereof Attn: CC Advocates Wef: 24/07/2006 04/09/2008 U.S.A. 23/03/2007

Vertex Pharmaceuticals 130 Waverly Street, Filing Date: 22/03/2007 C-Met Protein Kinase Wef: 22/03/2006 Warrant signed on 4146 Incorporated Cambridge, Massachusetts Rec: 1896/7 dt Vide PT 4146 Inhibitors Wef: 20/12/2006 04/09/2008 Attn: SS & Co. 02139, U.S.A. 12/04/2007

Filing Date: 27/03/2007 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 4147 Benzimidazole Derivatives Rec: 1893/4 dt Wef: 30/03/2006 Vide PT 4147 Attn: SS & Co. Basel, Switzerland 04/09/2008 12/04/2007

Processes for Preparing Fructuós Gelabert, 6-8, Filing Date: 29/03/2007 Ezetimibe and Intermediate Medichem S.A. Warrant signed on 4148 08970 Sant Joan Despí, Rec: 2022/3 dt Wef: 29/03/2006 Vide PT 4148 Compounds Useful for the Attn: SS & Co. 04/09/2008 Barcelona, Spain 16/04/2007 Preparation Thereof

Filing Date: 04/04/2007 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 4149 Chromen-2-one Derivatives Rec: 2424/5 dt Wef: 12/04/2006 Vide PT 4149 Attn: SS & Co. Basel, Switzerland 04/09/2008 08/05/2007

Filing Date: 04/04/2007 Novartis AG Lichtstrasse 35, 4056 Wef: 13/04/2006 Warrant signed on 4150 Organic Compounds Rec: 2426/7 dt Vide PT 4150 Attn: SS & Co. Basel, Switzerland Wef: 23/05/2006 04/09/2008 08/05/2007

Filing Date: 04/04/2007 Novartis AG Lichtstrasse 35, 4056 Wef: 11/04/2006 Warrant signed on 4151 Organic Compounds Rec: 2428/9 dt Vide PT 4151 Attn: SS & Co. Basel, Switzerland Wef: 17/10/2006 04/09/2008 08/05/2007 Filing Date: 17/04/2007 Novartis AG Lichtstrasse 35, 4056 Wef: 21/04/2006 Warrant signed on 4153 Organic Compounds Rec: 2055/6 dt Vide PT 4153 Attn: SS & Co. Basel, Switzerland Wef: 31/01/2007 04/09/2008 17/04/2007

126 East Lincoln Avenue, Merck & Co. Inc. & Merck Sharp Rahway NJ 07065, U.S.A. Filing Date: 17/04/2007 Quinolone M1 Receptor Warrant signed on 4154 & Dohme Limited & Hertford Road, Rec: 2061/2 dt Wef: N/A Vide PT 4154 Positive Allosteric Modulators 12/11/2008 Attn: CC Advocates Hoddeston, Hertfordshire 18/04/2007 EN11 9BU, England

Kitanomaru Square, 1-13- Filing Date: 19/04/2007 Dihydropyrazolopyrimidinone Banyu Pharmaceutical Co. Ltd. Warrant signed on 4155 12, Kudankita, Chiyoda-ku, Rec: 2115/6 dt Wef: 27/04/2006 Vide PT 4155 Derivatives Attn: CC Advocates 04/09/2008 Tokyo 102-8667, Japan 20/04/2007

Filing Date: 20/04/2007 Novartis AG Lichtstrasse 35, 4056 Warrant signed on 4156 Organic Compounds Rec: 2142/3 dt Wef: 21/04/2006 Vide PT 4156 Attn: SS & Co. Basel, Switzerland 04/09/2008 20/04/2007

Dialkylphenyl Compounds having beta2 Adrenergic 901 Gateway Boulevard, Filing Date: 24/04/2007 Theravance Inc. Warrant signed on 4157 Receptor Agonist and South San Francisco, CA Rec: 2197/8 dt Wef: 25/04/2006 Vide PT 4157 Attn: SS & Co. 04/09/2008 Muscarinic Receptor 94080, U.S.A. 25/04/2007 Antagonist Activity

901 Gateway Boulevard, Filing Date: 24/04/2007 Crystalline Forms of a Theravance Inc. Warrant signed on 4158 South San Francisco, CA Rec: 2200/1 dt Wef: 25/04/2006 Vide PT 4158 Dimethylphenyl Compound Attn: SS & Co. 04/09/2008 94080, U.S.A. 25/04/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 04/05/2007 IRM LLC Warrant signed on 4159 Compositions as Hedgehog Road, Hamilton, Bermuda Rec: 2356/7 dt Wef: 05/05/2006 Vide PT 4159 Attn: SS & Co. 07/10/2008 Pathway Modulators HM11 07/05/2007

Combino Pharm S.L. Fructuós Gelabert, 6-8, Filing Date: 07/05/2007 Solid Pharmaceutical Warrant signed on 4160 Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Rec: 2369/70 dt Wef: 08/05/2006 Vide PT 4160 Composition of Gabapentin 07/10/2008 Patentbureau Barcelona, Spain 07/05/2007

Salt Sensitivity and Bayer Schering Pharma Filing Date: 17/05/2007 Müllerstraße 178, Berlin Warrant signed on 4161 Prevention of Hypertension Aktiengesellschaft Rec: 2567/8 dt Wef: 17/05/2006 Vide PT 4161 13353, Germany 07/10/2008 with Drospirenone Attn: MAMO TCV Advocates 18/05/2007 Compounds and Hurst Holme, 12 Trott Filing Date: 23/05/2007 IRM LLC Wef: 23/05/2006 Warrant signed on 4162 Compositions as Channel Road, Hamilton, Bermuda Rec: 2634/5 dt Vide PT 4162 Attn: SS & Co. Wef: 22/11/2006 07/10/2008 Activating Protease Inhibitors HM11 23/05/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 23/05/2007 IRM LLC Wef: 23/05/2006 Warrant signed on 4163 Compositions as Channel Road, Hamilton, Bermuda Rec: 2637/8 dt Vide PT 4163 Attn: SS & Co. Wef: 22/11/2006 07/10/2008 Activating Protease Inhibitors HM11 23/05/2007

Lyophilized Preparations of Fructuós Gelabert, 6-8, Filing Date: 01/06/2007 Combino Pharm S.L. Warrant signed on 4165 Pantoprazole Sodium for 08970 Sant Joan Despí, Rec: 2799/80 dt Wef: 01/06/2006 Vide PT 4165 Attn: SS & Co. 08/10/2008 Injection Barcelona, Spain 01/06/2007

Processes for Preparing Fructuós Gelabert, 6-8, Filing Date: 08/06/2007 Intermediate Compounds Medichem S.A. Warrant signed on 4166 08970 Sant Joan Despí, Rec: 2868/70 dt Wef: 08/06/2006 Vide PT 4166 Useful for the Preparation of Attn: SS & Co. 08/10/2008 Barcelona, Spain 08/06/2007 Cinacalcet

Processes for Preparing Fructuós Gelabert, 6-8, Filing Date: 08/06/2007 Medichem S.A. Warrant signed on 4167 Cinacalcet Hydrochloride and 08970 Sant Joan Despí, Rec: 2872/3 dt Wef: 08/06/2006 Vide PT 4167 Attn: SS & Co. 08/10/2008 Polymorphic Forms Thereof Barcelona, Spain 08/06/2007

Global Intellectual Property, Patents, SE-151 AstraZeneca AB & Argenta 85 Sodertalje, Sweden & Filing Date: 11/06/2007 Cyclic Amine Derivatives and Warrant signed on 4168 Discovery Ltd. 8/9 Spire Green Centre, Rec: 2915/6 dt Wef: N/A Vide PT 4168 their uses 08/10/2008 Attn: CC Advocates Flex Meadow, Harlow, 12/06/2007 Essex CM19 5TR, United Kingdom

Arrow International Limited & 57 St. Christopher Street, Filing Date: 21/06/2007 Crystalline Duloxetine Chongqing Shenghuaxi Valletta VLT 08, Malta & Wef: 23/06/2006 Warrant signed on 4169 Rec: 3031/2 dt Vide PT 4169 Hydrochloride Pharmaceutical Co. Ltd. Renjiawan, Dashiba, Nan- Wef: 16/01/2007 08/10/2008 21/06/2007 Attn: SS & Co. an, Chongqing, China

Arrow International Limited & 57 St. Christopher Street, Filing Date: 21/06/2007 Crystalline Duloxetine Chongqing Shenghuaxi Valletta VLT 08, Malta & Warrant signed on 4170 Rec: 3035/6 dt Wef: 23/06/2006 Vide PT 4170 Hydrochloride Pharmaceutical Co. Ltd. Renjiawan, Dashiba, Nan- 08/10/2008 21/06/2007 Attn: SS & Co. an, Chongqing, China

Arrow International Limited & 57 St. Christopher Street, Filing Date: 21/06/2007 Crystalline Duloxetine Chongqing Shenghuaxi Valletta VLT 08, Malta & Warrant signed on 4171 Rec: 3038/9 dt Wef: 23/06/2006 Vide PT 4171 Hydrochloride Pharmaceutical Co. Ltd. Renjiawan, Dashiba, Nan- 08/10/2008 21/06/2007 Attn: SS & Co. an, Chongqing, China Novel Solid Forms of Fructuós Gelabert, 6-8, Filing Date: 22/06/2007 Rimonabant and Synthetic Medichem S.A. Warrant signed on 4172 08970 Sant Joan Despí, Rec: 3055/9 dt Wef: 22/06/2006 Vide PT 4172 Processes for Their Attn: SS & Co. 08/10/2008 Barcelona, Spain 22/06/2007 Preparation

18-Methyl-19-nor-androst-4-en 17, 17-spiroether (18-Methyl- Filing Date: 27/06/2007 Bayer Schering Pharma AG Warrant signed on 4173 19-nor-20-spirox-4-en-3-one), Berlin 13353, Germany Rec: 3102/3 dt Wef: 29/06/2006 Vide PT 4173 Attn: MAMO TCV Advocates 08/10/2008 sowie diese enthaltende 27/06/2007 pharmazeutische Praparate

Pharmaceutical Composition Bayer Schering Pharma Filing Date: 06/07/2007 Müllerstraße 178, Berlin Warrant signed on 4174 Containing a Tetrahydrofolic Aktiengesellschaft Rec: 3294/5 dt Wef: 06/07/2006 Vide PT 4174 13353, Germany 14/10/2008 Acid Attn: MAMO TCV Advocates 09/07/2007

Pharmaceutical Composition Bayer Schering Pharma Filing Date: 06/07/2007 for Contraception and for Müllerstraße 178, Berlin Wef: 06/07/2006 Warrant signed on 4175 Aktiengesellschaft Rec: 3291/2 dt Vide PT 4175 Reducing the risk of 13353, Germany Wef: 14/08/2006 14/10/2008 Attn: MAMO TCV Advocates 09/07/2007 congenital abnormalities

Filing Date: 09/07/2007 Improved Process for the Medichem S.A. Pol. Ind. Celrá, 17460 Warrant signed on 4177 Rec: 3304/5 dt Wef: 13/07/2006 Vide PT 4177 Preparation of Voriconazole Attn: CC Advocates Celrá, Girona, Spain 14/10/2008 09/07/2007

Improved Processes for Fructuós Gelabert, 6-8, Filing Date: 13/07/2007 Medichem S.A. Warrant signed on 4178 Preparing Venlafaxine Base 08970 Sant Joan Despí, Rec: 3431/3 dt Wef: 14/07/2006 Vide PT 4178 Attn: SS & Co. 14/10/2008 and Salts Thereof Barcelona, Spain 17/07/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 20/07/2007 IRM LLC Wef: 21/07/2006 Warrant signed on 4179 Compositions as ITPKb Road, Hamilton, Bermuda Rec: 3506/7 dt Vide PT 4179 Attn: SS & Co. Wef: 08/03/2007 14/10/2008 Inhibitors HM11 20/07/2007

Filing Date: 24/07/2007 Amino Chemicals Limited A61 Industrial Estate, Warrant signed on 4180 Irbesartan Intermediate Rec: 3552/3 dt Wef: N/A Vide PT 4180 Attn: Dr John Cremona Marsa LQA 06, Malta 14/10/2008 25/07/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 25/07/2007 IRM LLC Wef: 25/07/2006 Warrant signed on 4181 Compositions as Hedgehog Road, Hamilton, Bermuda Rec: 3566/7 dt Vide PT 4181 Attn: SS & Co. Wef: 07/06/2007 14/10/2008 Pathway Modulators HM11 26/07/2007 SmithKline Beecham One Franklin Plaza, P.O. Filing Date: 26/07/2007 Novel Pharmaceutical Wef: 03/05/2006 Warrant signed on 4182 Corporation Box 7929, Philadelphia, PA Rec: 3611/2 dt Vide PT 4182 Composition Wef: 03/07/2007 16/12/2008 Attn: SS & Co. 19101, U.S.A. 26/07/2007

Method for Preparing Fructuós Gelabert, 6-8, Filing Date: 30/07/2007 Medichem S.A. Warrant signed on 4183 Polymorph Form II of 08970 Sant Joan Despí, Rec: 3722/4 dt Wef: N/A Vide PT 4183 Attn: SS & Co. 30/01/2009 Gabapentin Barcelona, Spain 31/07/2007

Fructuós Gelabert, 6-8, Filing Date: 02/08/2007 Improved Method for Medichem S.A. Warrant signed on 4184 08970 Sant Joan Despí, Rec: 3783/4 dt Wef: 02/08/2006 Vide PT 4184 Synthesizing Lamotrigine Attn: SS & Co. 14/10/2008 Barcelona, Spain 02/08/2007

Improved Process for Fructuós Gelabert, 6-8, Filing Date: 03/08/2007 Synthesizing Desvenlafaxine Medichem S.A. Wef: 04/08/2006 Warrant signed on 4185 08970 Sant Joan Despí, Rec: 3846/7 dt Vide PT 4185 Free Base and Salts or Attn: SS & Co. Wef: 06/04/2007 14/10/2008 Barcelona, Spain 06/08/2007 Solvates Thereof

Bayer Schering Pharma Filing Date: 10/08/2007 Peroral Medicament form for Müllerstraße 178, Berlin Warrant signed on 4186 Aktiengesellschaft Rec: 4004/5 dt Wef: 10/08/2006 Vide PT 4186 contraception 13353, Germany 14/10/2008 Attn: MAMO TCV Advocates 13/08/2007

Improved Method for Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 06/09/2007 Wef: 07/09/2006 Warrant signed on 4193 Preparing 1,3-disubstituted Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Rec: 4514/5 dt Vide PT 4193 Wef: 07/05/2007 22/10/2008 Pyrrolidine Compounds Patentbureau Barcelona, Spain 10/09/2007

The Regents of the University of Compounds Having Activity in 1111 Franklin Street, 12th Filing Date: 17/09/2007 California 4196 Correcting Mutant-CFTR Floor, Oakland, California Rec: 4698/9 dt Wef: N/A REFUSED Not Available Attn: Bezzina & Mifsud Processing and Uses Thereof 94607-5200, U.S.A. 18/09/2007 Patentbureau

Hurst Holme, 12 Trott Compounds and Road, Hamilton, Bermuda Filing Date: 27/09/2007 IRM LLC & Novartis AG Warrant signed on 4197 Compositions as Protein HM11 & Lichtstrasse 35, Rec: 4830/1 dt Wef: 02/10/2006 Vide PT 4197 Attn: SS & Co. 23/10/2008 Kinase Inhibitors CH-4056 Basel, 27/09/2007 Switzerland

Ardagh Cottage, Carrowbeg, Newport, Filing Date: 05/10/2007 Prediction Method and Julian Ellison & Yoshi Nishio 4198 County Mayo, Ireland & 25 Rec: 5061/2 dt Wef: 08/10/2006 REFUSED Vide PT 4198 System Attn: SS & Co. Montpelier Square, London 05/10/2007 SW7 1JR, U.K. Improved Process for Fructuós Gelabert, 6-8, Filing Date: 16/10/2007 Preparing Donepezil, Medichem S.A. Wef: 16/10/2006 Warrant signed on 4199 08970 Sant Joan Despí, Rec: 5242/3 dt Vide PT 4199 Hyrochloride Polymorphic Attn: SS & Co. Wef: 18/06/2007 23/10/2008 Barcelona, Spain 16/10/2007 Form I

P-Toluene Sulfonic Acid Salt of 5-amino-3-(2'O-Acetyl- Anadys Pharmaceuticals Inc. 3115 Merryfield Row, San Filing Date: 17/10/2007 Wef: 17/10/2006 3'Deoxy-β-D-Ribofuranosyl)- Warrant signed on 4200 Attn: Bezzina & Mifsud Diego, California 92121, Rec: 5271/2 dt Wef: 05/02/2007 Vide PT 4200 3H-Thiazole[4,5-d]pyrimidine- 23/10/2008 Patentbureau U.S.A. 18/10/2007 Wef: 02/08/2007 2-one and Methods for Preparation

Compositions and Methods Hurst Holme, 12 Trott Filing Date: 18/10/2007 IRM LLC Warrant signed on 4201 for Modulating C-KIT and Road, Hamilton, Bermuda Rec: 5274/5 dt Wef: 20/10/2006 Vide PT 4201 Attn: SS & Co. 23/10/2008 PDGFR Receptors HM11 18/10/2007

Hurst Holme, 12 Trott Filing Date: 09/11/2007 Agonist TRKB Anitbodies and IRM LLC Warrant signed on 4203 Road, Hamilton, Bermuda Rec: 5620/1 dt Wef: 09/11/2006 Vide PT 4203 Uses Thereof Attn: SS & Co. 23/10/2008 HM11 09/11/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 07/12/2007 IRM LLC Warrant signed on 4206 Compositions as Protein Road, Hamilton, Bermuda Rec: 5992/3 dt Wef: 08/12/2006 Vide PT 4206 Attn: SS & Co. 23/10/2008 Kinase Inhibitors HM11 10/12/2007

One Procter & Gamble Filing Date: 14/12/2007 Compositions of Azimilide The Procter & Gamble Company Warrant signed on 4207 Plaza, Cincinnati, OH Rec: 6100/1 dt Wef: 15/12/2006 Vide PT 4207 Dihydrochloride Attn: S S & Co. 23/10/2008 4202, U.S.A. 17/12/2007

Compounds and Hurst Holme, 12 Trott Filing Date: 14/12/2007 Compositions as Inhibitors of IRM LLC Wef: 15/12/2006 Warrant signed on 4208 Road, Hamilton, Bermuda Rec: 6103/4 dt Vide PT 4208 Cannabinoid Receptor 1 Attn: SS & Co. Wef: 02/08/2007 23/10/2008 HM11 17/12/2007 Activity

Fructuós Gelabert, 6-8, Filing Date: 21/12/2007 Crystalline Solid Forms of O- Medichem S.A. Warrant signed on 4210 08970 Sant Joan Despí, Rec: 62191/2 dt Wef: 22/12/2006 Vide PT 4210 Desvenlafaxine Base Attn: SS & Co. 23/10/2008 Barcelona, Spain 26/12/2007

Compounds and Hurst Holme, 12 Trott IRM LLC Filing Date: 10/01/2008 Wef: 10/01/2007 Warrant signed on 4211 Compositions as Channel Road, Hamilton, Bermuda Vide PT 4211 Attn: SS & Co. Rec: 120/1 dt 10/01/2008 Wef: 23/02/2007 12/11/2008 Activating Protease Inhibitors HM11

Medichem S.A. Fructuós Gelabert, 6-8, Process for Preparing Filing Date: 10/01/2008 Warrant signed on 4212 Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 10/01/2007 Vide PT 4212 Vildagliptin Rec: 134/5 dt 10/01/2008 16/12/2008 Patentburea Barcelona, Spain Improved Process for Fructuós Gelabert, 6-8, Synthesizing Desvenlafaxine Medichem S.A. Filing Date: 22/01/2008 Warrant signed on 4213 08970 Sant Joan Despí, Wef: 22/01/2007 Vide PT 4213 Free Base and Salts or Attn: SS & Co. Rec: 354/5 dt 22/01/2008 12/11/2008 Barcelona, Spain Solvates Thereof

Compounds and Hurst Holme, 12 Trott IRM LLC Filing Date: 01/02/2008 Warrant signed on 4214 Compositions as Modulators Road, Hamilton, Bermuda Wef: 02/02/2007 Vide PT 4214 Attn: S S & Co. Rec: 541/2 dt 04/02/2008 12/11/2008 of GPR119 Activity HM11

Improved Process for Hurst Holme, 12 Trott Synthesizing Desvenlafaxine IRM LLC Filing Date: 08/02/2008 Warrant signed on 4215 Road, Hamilton, Bermuda Wef: 09/02/2007 Vide PT 4215 Free Base and Salts or Attn: SS & Co. Rec: 606/7 dt 08/02/2008 12/11/2008 HM11 Solvates Thereof

Fructuós Gelabert, 6-8, Filing Date: 28/03/2008 An Improved Process for the Medichem S.A. Wef: 30/03/2007 Warrant signed on 4216 08970 Sant Joan Despí, Rec: 1587/8 dt Vide PT 4216 Synthesis of Solifenacin Attn: SS & Co. Wef: 08/05/2007 12/11/2008 Barcelona, Spain 28/03/2008

Anadys Pharmaceuticals Inc. 3115 Merryfield Row, San Filing Date: 28/03/2008 5,6-Dihydro-1H-Pyridin-2-One Warrant signed on 4217 Attn: Bezzina & Mifsud Diego, California 92121, Rec: 1584/5 dt Wef: 03/04/2007 Vide PT 4217 Compounds 12/11/2008 Patentbureau U.S.A. 28/03/2008

A Method for Determining Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 13/06/2008 Warrant signed on 4222 Enantiomeric Purity of Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Rec: 2915/6 dt Wef: 15/06/2007 Vide PT 4222 09/01/2009 Darifenacin and Intermediates Patenbureau Barcelona, Spain 17/06/2008

Fructuós Gelabert, 6-8, Filing Date: 18/06/2008 Aqueous Formulations of Combino Pharm S.L. Warrant signed on 4223 08970 Sant Joan Despí, Rec: 2934/5 dt Wef: 18/06/2007 Vide PT 4223 Acetaminophen for Injection Attn: SS & Co. 09/01/2009 Barcelona, Spain 19/06/2008

Fructuós Gelabert, 6-8, Filing Date: 18/06/2008 Aqueous Formulations of Combino Pharm S.L. Warrant signed on 4224 08970 Sant Joan Despí, Rec: 2936/7 dt Wef: 18/06/2007 Vide PT 4224 Acetaminophen for Injection Attn: SS & Co. 09/01/2009 Barcelona, Spain 19/06/2008 MT PT No Patent Title Applicant Name Applicant Address MT Filing Date Priority Date Status Abstract

Oral Delayed-Release Fructuós Gelabert, 6-8, Combino Pharm S.L. Filing Date: 09/07/2008 Warrant signed on 4226 Dulxetine Hydrochloride 08970 Sant Joan Despí, Wef: 09/07/2007 Vide PT 4226 Attn: SS & Co. Rec: 3254/5 dt 09/07/2008 30/01/2009 Pellets Barcelona, Spain

Amorphous Form of Fructuós Gelabert, 6-8, Darifenacin Hydrobromide Medichem S.A. Filing Date: 11/07/2008 Warrant signed on 4227 Sant Joan Despí, Wef: 13/07/2007 Vide PT 4227 and Processes for the Att: B&M Patentbureau Rec: 3443/4 dt 22/07/2008 30/01/2009 Barcelona 08970, Spain Preparation Thereof

Compounds and Hurst Holme, 12 Trott IRM LLC Filing Date: 22/08/2008 Warrant signed on 4228 Compositions as Kinase Road, Hamilton, Bermuda Wef: 22/08/2007 Vide PT 4228 Attn: SS & Co. Rec: 3851/2 dt 22/08/2008 11/03/2009 Inhibitors HM11

Novel Pharmaceutical Fructuós Gelabert, 6-8, Combino Pharm S.L. Filing Date: 05/09/2008 Warrant signed on 4229 Compositions Comprising 08970 Sant Joan Despí, Wef: 06/09/2007 Vide PT 4229 Attn: SS & Co. Rec: 4234/5 dt 22/09/2008 30/03/2009 Lamivudine Barcelona, Spain

Improved Process for Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 18/09/2008 Wef: 18/09/2007 Warrant signed on 4231 Preparing Cinacalcet 08970 Sant Joan Despí, Vide PT 4231 Attn: SS & Co. Rec: 4197/8 dt 18/09/2008 Wef: 10/03/2008 06/05/2009 Hydrochloride Barcelona, Spain

An Improved Process for Fructuós Gelabert, 6-8, Filing Date: 17/10/2008 Medichem S.A. Warrant signed on 4234 Preparing a 2,4- 08970 Sant Joan Despí, Rec: 4649/50 dt Wef: 17/10/2007 Vide PT 4234 Attn: CC Advocates 06/05/2009 Thiazolidinedione Derivative Barcelona, Spain 17/10/2008

Fructuós Gelabert, 6-8, Improved Process for Medichem S.A. Filing Date: 05/11/2008 Warrant signed on 4237 08970 Sant Joan Despí, Wef: 06/11/2007 Vide PT 4237 Preparing Duloxetine Attn: SS & Co. Rec: 5216/7 dt 06/11/2008 08/06/2009 Barcelona, Spain

Improved Processes for the Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 19/11/2008 Warrant signed on 4240 Synthesis of Varenicline L- 08970 Sant Joan Despí, Wef: 20/11/2007 Vide PT 4240 Attn: SS & Co. Rec: 5643/4 dt 19/11/2008 08/06/2009 Tartrate Barcelona, Spain

Processes for Preparing a Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 25/11/2008 Warrant signed on 4241 Substituted Gamma-Amino Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Rec: 5849/80 dt Wef: 30/11/2007 Vide PT 4241 08/06/2009 Acid Patentbureau Barcelona, Spain 27/11/2008

Polymorphic Forms of A 3- Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 12/12/2008 Warrant signed on 4246 Pyrrole Substituted 2- Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 12/12/2007 Vide PT 4246 Rec: 6496/7 dt 18/12/2008 17/07/2009 Indolinone Patentbureau Barcelona, Spain

Method for Determining the Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 23/01/2009 Warrant signed on 4248 Enantiomeric Purity of Indane Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 25/01/2008 Vide PT 4248 Rec: 603/4 dt 28/01/2009 10/08/2009 Derivatives Patentbureau Barcelona, Spain

A New Polymorphic Form of a Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 12/02/2009 Warrant signed on 4249 Pyrazino [2,3-h][3] 08970 Sant Joan Despí, Wef: 15/02/2008 Vide PT 4249 Attn: SS & Co. Rec: 1035/6 dt 12/02/2009 15/09/2009 Benzazepine Derivative Barcelona, Spain Medichem S.A. Fructuós Gelabert, 6-8, Wef: 28/02/2008 Process for Preparing Indane Filing Date: 27/02/2009 Warrant signed on 4251 Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 19/03/2008 Vide PT 4251 Derivatives Rec: 4700 of 18/09/2007 15/09/2009 Patentbureau Barcelona, Spain Wef: 24/09/2008

Fructuós Gelabert, 6-8, Salts of a Pyrazino[2,3- Medichem S.A. Filing Date: 05/03/2009 Wef: 06/03/2008 Warrant signed on 4252 08970 Sant Joan Despí, Vide PT 4252 h][3]benzazepine Derivative Attn: SS & Co. Rec: 1492/3 dt 05/03/2009 Wef: 08/04/2008 22/10/2009 Barcelona, Spain

Polymorphic Form of an Fructuós Gelabert, 6-8, Medichem S.A. Filing Date: 27/03/2009 Warrant signed on 4253 Aminoindan Mesylate 08970 Sant Joan Despí, Wef: 28/03/2008 Vide PT 4253 Attn: SS & Co. Rec: 1895/6 dt 27/03/2009 22/10/2009 Derivative Barcelona, Spain

Process for Controlling the Fructuós Gelabert, 6-8, Particle size of a 3- Medichem S.A. Filing Date: 04/05/2009 Wef: 05/05/2008 Warrant signed on 4254 08970 Sant Joan Despí, Vide PT 4254 (trifluoromethyl)phenyl-1- Attn: SS & Co. Rec: 2495 dt 05/05/2009 Wef: 10/09/2008 22/12/2009 Barcelona, Spain aminopropane Derivative

A New Method for Obtaining Fructuós Gelabert, 6-8, Filing Date: 22/05/2009 Medichem S.A. Warrant signed on 4257 an Aminoindan Mesylate 08970 Sant Joan Despí, Rec: 2739/40 dt Wef: 23/05/2008 Vide PT 4257 Attn: SS & Co. 22/12/2009 Derivative Barcelona, Spain 22/05/2009

Process for Preparing A 3- Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 12/06/2009 Warrant signed on 4258 Pyrrole Substituted 2- Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 13/06/2008 Vide PT 4258 Rec: 3071/2 dt 16/06/2009 09/02/2010 Indolinone Malate Salt Patentbureau Barcelona, Spain

Process for Preparing a Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 12/06/2009 Wef: 13/06/2008 Warrant signed on 4259 Benzoylbenzeneacetamide Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Vide PT 4259 Rec: 3074/6 dt 16/06/2009 Wef: 25/11/2008 09/02/2010 Derivative Patentbureau Barcelona, Spain

Medichem S.A. Fructuós Gelabert, 6-8, Process for Preparing a Filing Date: 19/06/2009 Warrant signed on 4260 Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 19/06/2008 Vide PT 4260 Piperazine Derivative Rec: 3186/7 dt 25/06/2009 09/02/2010 Patentbureau Barcelona, Spain

Process for Preparing 3- Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 19/06/2009 Warrant signed on 4261 Substituted Pyrrolidine Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Rec: 3189/90 dt Wef: 19/06/2008 Vide PT 4261 22/12/2009 Compounds Patentbureau Barcelona, Spain 25/06/2009

Amorphous Form of A 3- Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 26/06/2009 Warrant signed on 4262 Pyrrole Substituted 2- Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 26/06/2008 Vide PT 4262 Rec: 3250/1 dt 01/07/2009 09/02/2010 Indolinone Malate Salt Patentbureau Barcelona, Spain

Novel Pharmaceutical Compositions Comprising Combino Pharm S.L. Fructuós Gelabert, 6-8, Poly(allylamin-Co-N,N'-Diallyl- Filing Date: 03/07/2009 Warrant signed on 4263 Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 26/06/2008 Vide PT 4263 1,3-Diamino-2- Rec: 3340/1 dt 10/07/2009 09/02/2010 Patentbureau Barcelona, Spain Hydroxypropane) Hydrochloride Fructuós Gelabert, 6-8, Filing Date: 16/07/2009 Method of Assaying an Combino Pharm S.L. Warrant signed on 4265 08970 Sant Joan Despí, Rec: 3429/30 dt Wef: 17/07/2008 Vide PT 4265 aminoadamantane Derivative Attn: SS & Co. 09/02/2010 Barcelona, Spain 17/07/2009

Fructuós Gelabert, 6-8, New Salt Forms of an Medichem S.A. Filing Date: 20/07/2009 Warrant signed on 4266 08970 Sant Joan Despí, Wef: 18/07/2008 Vide PT 4266 Aminoindan Derivative Attn: SS & Co. Rec: 3446/7 dt 20/07/2009 09/02/2010 Barcelona, Spain

Crystalline Forms of a 3- Medichem S.A. Fructuós Gelabert, 6-8, Filing Date: 24/07/2009 Warrant signed on 4267 Pyrrole Substituted 2- Attn: Bezzina & Mifsud 08970 Sant Joan Despí, Wef: 24/07/2008 Vide PT 4267 Rec: 3541/2 dt 24/07/2009 09/02/2010 Indolinone Malate Salt Patentbureau Barcelona, Spain

Methods of using Sustained 15 Skyline Drive, Filing Date: 10/09/2009 Accorda Therapeutics Inc. Warrant signed on 4268 release aminopyridine Hawthorne, NY 10532, Rec: 4169/70 dt Wef: 10/09/2008 Vide PT 4268 Attn: SS & Co. 12/04/2010 compositions U.S.A. 14/09/2009