2019 Abstracts
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We are delighted EDITORIAL to welcome the worldwide yeast community in Gothenburg for ICYGMB2019! The “International Yeast Conferences” started in the 1960s with a handful of delegates and since then have become THE most important event in yeast research. Now the yeast meeting to returns to Gothenburg. Many yeast researchers still remember the meeting in 2003 with over 1,100 delegates, a truly memorable event. The Life Sciences are changing, and yeast research remains at their forefront. Advancements in genome sequencing and genome editing just make yeast more exciting as model organism in basic cell biological research, genome evolution and as a tool for synthetic biology and biotechnology. One of the most important reasons for the enormous success of yeast research lies in the unique character of the international yeast research community. No other community employs such a free exchange and access to information and research tools. Nor has any other community had the ability to build – even intercontinental – consortia of critical mass to tackle large‐scale projects, such as in sequencing the first eukaryotic genome or the first comprehensive yeast knockout library. Yeast2019 is the meeting of the international yeast research community where the latest, and even unpublished results are exchanged, and new projects, alliances, and collaborations are founded. A do‐not‐miss‐event. We attempt to incorporate the present excitement in yeast research in the programme of yeast2019. We are confident that this conference will contain important news and information for all yeast researchers. Taken together, yeast2019 will provide an up‐ to‐date overview in yeast research and it will set the scene for years to come. After all, it is one of the most affordable international conferences of such as size and reputation! On behalf of the organising committee, Stefan HOHMANN, chair ICYGMB2019 Gothenburg Committees STEERING COMMITTEE Stefan Hohmann, chairman Terrance G. Cooper, secretary Jiří Hašek , chair of yeast2017 FINANCE AND POLICY COMMITTEE OF THE YEAST RESEARCH COMMUNITY Australia: Ian W. Dawes Mexico: Alejandra Covarrubias Austria: Diethard Mattanovich The Netherlands: Han de Winde Belgium: Johan Thevelein New Zealand: Richard Gardner Brazil: Ana Clara G. Schenberg Norway: Odd S. Gabrielsen Bulgaria: George Miloshev Poland: Teresa Zoladek Canada: Brenda Andrews Portugal: Claudina Rodrigues‐Pousada Czech Republic: Jiří Hašek Russia: Serge G. Inge‐Vechtomov Denmark: Jürgen Wendland Slovakia: Lubomir Tomaska Finland: Matti Korhola Slovenia: Peter Raspor France: Joseph Schacherer South Africa: Florian Bauer Germany: Karl‐Dieter Entian Spain: Andres Aguilera Hungary: Matthias Sipiczki Sweden: Stefan Hohmann Ireland: Ursula Bond Switzerland: Claudio De Virgilio Israel: Martin Kupiec Tunisia: Omrane Belhadj Italy: Duccio Cavalieri Ukraine: Andrei Sibirny Japan: Yoshikazu Ohya United Kingdom: Stephen G. Oliver Lithuania: Kestutis V. Sasnaukas United States: Terrance G. Cooper LOCAL ORGANISING COMMITTEE From Chalmers University of Technology: Stefan Hohmann (Chair) Jens Nielsen, Dina Petranovic, Lisbeth Olsson, Carl Johan Franzén, Cecilia Gejer, Mikael Molin, Florian David, Verena Siewers, Kate Campbell, Christer Larsson, Joakim Norbeck, Thomas Andlid From the University of Gothenburg: Anders Blomberg, Thomas Nyström, Per Sunnerhagen, Claes Gustafsson, Markus Tamás, Beidong Liu, Jonas Warringer, Marija Cvijovic From the Umeå University: Stefan Björklund EXECUTIVE COMMITTEE Stefan HOHMANN (Chair), Mikael MOLIN (secretary), Jonas WARRINGER, Florian DAVID, Verena SIEWERS, Anders BLOMBERG, Per SUNNERHAGEN, Marija CVIJOVIC Practical information ORAL PRESENTATIONS Presentations should be uploaded to the conference computers before the respective session. In each room both PC and MAC computers are available. POSTER PRESENTATIONS Poster numbers are corresponding to your submission number. Please mount your posters on Sunday. Schedule for poster presentations: Monday: even posters Tuesday (lunch): odd poster Tuesday (evening): all posters Wednesday: all posters Three Poster prizes will be announced during the conference dinner SPEAKERS’ CORNER All keynote and plenary speakers are kindly invited to join the speakers´ corner where conference participants will have the possibility to meet them. Each speaker will have a volunteer assigned that will help them find their way. Speakers should be present during the speakers´ corner session that directly follows their presentation: Speakers presenting Sunday or Monday morning: speakers´ corner Monday 14.00‐16.00 Speakers presenting Monday afternoon or Tuesday morning: speakers´ corner Tuesday 14.00‐16.00 Speakers presenting Tuesday afternoon or Wednesday morning: speakers´ corner Wednesday 14.00‐16.00 Speakers presenting Wednesday afternoon or Thursday: speakers´ corner Thursday 13.00‐14.00 WI‐FI network: YEAST2019 Password: YEAST2019 TWITTER Please use #yeast2019 Sponsors Bronze Opening keynote lectures Welcome reception Poster prize Other Program Overview SUNDAY AUGUST 18 Main auditorium F1+F2 F4 F5 12:00 Registration; poster mounting 16:00 Opening ceremony 16:30 Frederick ROTH, Toronto, Canada 17:30 Roger KORNBERG, Stanford, USA 18:30 Welcome reception MONDAY AUGUST 19 08:30 Sensing, signaling and stress responses 10:30 Coffee break 11:00 Stress signalling and (protein) trafficking Modern yeast biotechnology Controlling gene expression 13:00 Lunch, Poster session, Speaker’s corner, SGD Q&A , Exhibitions, Coffee 16:00 Gene expression, RNA processing and regulation 18:00 ICYGMB special lecture: Steve OLIVER TUESDAY AUGUST 20 08:30 Metabolism and metabolic regulation 10:30 Coffee break 11:00 Metabolism and organelles RNA biology Cell growth, division and morphogenesis 13:00 Lunch, Poster session, Speaker’s corner, SGD Q&A, Exhibitions, Coffee Meeting of the Finance and Policy Committee of the International Yeast Community (members ‐ on invitation only): 1300‐1500 room R13 16:00 Biotechnology and synthetic biology 18:00 Poster session and social activities (live music, bar) WEDNESDAY AUGUST 21 08:30 Evolution and population genetics 10:30 Coffee break 11:00 Pathogens and host interaction Ageing and disease models Population, comparative and evolutionary genomics 13:00 Lunch, Poster session, Speaker’s corner, Exhibitions, Coffee, SGD Workshop 16:00 Cell cycle and cell fate 19:00 Conference dinner THURSDAY AUGUST 22 08:30 Quality control, organelles and aging 10:30 Coffee break 11:00 Yeast molecular networks Proteostasis Heterologous gene function and drug discovery 13:00 Lunch, Speaker’s corner, SGD Q&A , Coffee 14:00 DNA replication, mutation and repair 16:00 Susan GASSER, Basel, Switzerland 17:00 Closing ceremony Detailed Program SUNDAY AUGUST 18 Main auditorium F1+F2 F4 F5 12:00 Registration; poster mounting 16:00 Opening ceremony 16:30 Chair: Kenneth Wolfe Frederick ROTH, University of Toronto, Canada Using yeast to map environment‐ dependent protein networks and functional human sequence variation 17:30 Chair: Jean Beggs Roger Kornberg, Stanford University, USA Chromosome Structure and Transcription 18:30 Welcome reception MONDAY AUGUST 19 Main auditorium F1+F2 F4 F5 08:30 Chair: Stephen Oliver Sensing, signaling and stress responses Francesc POSAS, Institute for Research in Biomedicine (IRB Barcelona), Spain 08:30‐09:00 Adaptation to Osmostress by the HOG1 SAPK Symeon SINNIOSSOGLOU, University of Cambridge, UK 09:00‐09:30 Compartmentalized Synthesis of Triacylglycerol Regulates Nuclear Membrane Homeostasis During Stress Peter SWAIN, University of Edinburgh, UK 09:30‐10:00 Cellular decision‐making in changing environments Martha CYERT, Stanford University, USA 10:00‐10:30 Networks for the Calcineurin Phosphatase in Yeast and Humans Reveal Evolution of Signaling 10:30 Coffee break 11:00 Stress signalling and Modern yeast biotechnology Controlling gene (protein) trafficking expression Chairs: Mikael Molin and Claudio Chairs: Florian David and Petri‐Jaan Chairs: Stefan Björklund and De Virgilio Lahtvee David Shore 11.00 Sabine ROSPERT, 11.00 Filipa PEREIRA, EMBL 11.00 Shira URIM, Israel University of Freiburg, Germany Heidelberg, Germany Institute of Technology, Israel The Hsp70 Homolog Ssb: a novel In silico Yeast Chassis Design for “mRNA Imprinting": Component of the TORC1/Sch9 Accelerated Cell Factory Regulation of Gene Signaling Network Development Expression by Co‐ transcriptionally Associating 11.15 Julie PARENTEAU, 11.15 Florian DAVID, Chalmers, Université de Sherbrooke, Canada Sweden Proteins Mechanisms of Intron Mediated Framework for Model Assisted 11.15 Nozomu SAEKI, Nutrients Sensing and Generation of Platform Strains Okayama University, Japan Resistance to Starvation through CRISPR Mediated Fine‐ Systematic Identification of tuning of Central Carbon Genes whose Overexpression 11.30 Riko HATEKEYAMA, Metabolism Université de Fribourg, Switzerland Positively Affect Fitness in Emerging Links Between TORC1 Various Environments Signaling And Intracellular Trafficking 11.45 Silvia SOTO DIAZ, 11.30 Thomas NICOLAÏ, KU 11.30 Asli AZIZOGLU, ETH Université Libre de Bruxelles, Leuven, Belgium Zürich, Switzerland Belgium Production Of Muconic Acid And The Well‐Tempered Characterization of theactivity Protocatechuic Acid From Controller‐846: A Precisely regulation of Mep‐Amt‐Rh Lignocellulosic Feedstock Titratable and Tight ammonium transport proteins Transcriptional Controller in 11.45 Tomas STRUCKO, Danish by TORC1‐Npr1‐Amu1/Par32 in University of Technology, Lyngby, S. cerevisiae Saccharomyces cerevisiae